-
1
-
-
44649120132
-
Chemokine signaling via the CXCR2 receptor reinforces senescence
-
Acosta, J.C., O'loghlen, A., Banito, A., Guijarro, M.V., Augert, A., Raguz, S., Fumagalli, M., Da Costa, M., Brown, C., Popov, N., Takatsu, Y., Melamed, J., D'adda Di Fagagna, F., Bernard, D., Hernando, E., Gil, J., Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell 133 (2008), 1006–1018.
-
(2008)
Cell
, vol.133
, pp. 1006-1018
-
-
Acosta, J.C.1
O'loghlen, A.2
Banito, A.3
Guijarro, M.V.4
Augert, A.5
Raguz, S.6
Fumagalli, M.7
Da Costa, M.8
Brown, C.9
Popov, N.10
Takatsu, Y.11
Melamed, J.12
D'adda Di Fagagna, F.13
Bernard, D.14
Hernando, E.15
Gil, J.16
-
2
-
-
84940404091
-
Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease
-
Ahmad, T., Sundar, I.K., Lerner, C.A., Gerloff, J., Tormos, A.M., Yao, H., Rahman, I., Impaired mitophagy leads to cigarette smoke stress-induced cellular senescence: implications for chronic obstructive pulmonary disease. FASEB J. 29 (2015), 2912–2929.
-
(2015)
FASEB J.
, vol.29
, pp. 2912-2929
-
-
Ahmad, T.1
Sundar, I.K.2
Lerner, C.A.3
Gerloff, J.4
Tormos, A.M.5
Yao, H.6
Rahman, I.7
-
3
-
-
84999766469
-
Senescence of T lymphocytes: implications for enhancing human immunity
-
Akbar, A.N., Henson, S.M., Lanna, A., Senescence of T lymphocytes: implications for enhancing human immunity. Trends Immunol. 37 (2016), 866–876.
-
(2016)
Trends Immunol.
, vol.37
, pp. 866-876
-
-
Akbar, A.N.1
Henson, S.M.2
Lanna, A.3
-
4
-
-
84889100159
-
Loss of iron triggers PINK1/Parkin-independent mitophagy
-
Allen, G.F., Toth, R., James, J., Ganley, I.G., Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep. 14 (2013), 1127–1135.
-
(2013)
EMBO Rep.
, vol.14
, pp. 1127-1135
-
-
Allen, G.F.1
Toth, R.2
James, J.3
Ganley, I.G.4
-
5
-
-
84958093401
-
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan
-
Baker, D.J., Childs, B.G., Durik, M., Wijers, M.E., Sieben, C.J., Zhong, J., Saltness, R.A., Jeganathan, K.B., Verzosa, G.C., Pezeshki, A., Khazaie, K., Miller, J.D., Van Deursen, J.M., Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan. Nature 530 (2016), 184–189.
-
(2016)
Nature
, vol.530
, pp. 184-189
-
-
Baker, D.J.1
Childs, B.G.2
Durik, M.3
Wijers, M.E.4
Sieben, C.J.5
Zhong, J.6
Saltness, R.A.7
Jeganathan, K.B.8
Verzosa, G.C.9
Pezeshki, A.10
Khazaie, K.11
Miller, J.D.12
Van Deursen, J.M.13
-
6
-
-
84914165449
-
Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls
-
Bannister, C.A., Holden, S.E., Jenkins-Jones, S., Morgan, C.L., Halcox, J.P., Schernthaner, G., Mukherjee, J., Currie, C.J., Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls. Diabetes Obes. Metab. 16 (2014), 1165–1173.
-
(2014)
Diabetes Obes. Metab.
, vol.16
, pp. 1165-1173
-
-
Bannister, C.A.1
Holden, S.E.2
Jenkins-Jones, S.3
Morgan, C.L.4
Halcox, J.P.5
Schernthaner, G.6
Mukherjee, J.7
Currie, C.J.8
-
7
-
-
84879655699
-
Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1alpha
-
Bartoletti-Stella, A., Mariani, E., Kurelac, I., Maresca, A., Caratozzolo, M.F., Iommarini, L., Carelli, V., Eusebi, L.H., Guido, A., Cenacchi, G., Fuccio, L., Rugolo, M., Tullo, A., Porcelli, A.M., Gasparre, G., Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1alpha. Cell Death Dis., 4, 2013, e663.
-
(2013)
Cell Death Dis.
, vol.4
-
-
Bartoletti-Stella, A.1
Mariani, E.2
Kurelac, I.3
Maresca, A.4
Caratozzolo, M.F.5
Iommarini, L.6
Carelli, V.7
Eusebi, L.H.8
Guido, A.9
Cenacchi, G.10
Fuccio, L.11
Rugolo, M.12
Tullo, A.13
Porcelli, A.M.14
Gasparre, G.15
-
8
-
-
84964890374
-
Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling
-
Brand, M.D., Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling. Free Radic. Biol. Med. 100 (2016), 14–31.
-
(2016)
Free Radic. Biol. Med.
, vol.100
, pp. 14-31
-
-
Brand, M.D.1
-
9
-
-
0242333997
-
Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin
-
Brennan, M., Bhatti, H., Nerusu, K.C., Bhagavathula, N., Kang, S., Fisher, G.J., Varani, J., Voorhees, J.J., Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin. Photochem. Photobiol. 78 (2003), 43–48.
-
(2003)
Photochem. Photobiol.
, vol.78
, pp. 43-48
-
-
Brennan, M.1
Bhatti, H.2
Nerusu, K.C.3
Bhagavathula, N.4
Kang, S.5
Fisher, G.J.6
Varani, J.7
Voorhees, J.J.8
-
10
-
-
84961290427
-
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
-
Bueno, M., Lai, Y.C., Romero, Y., Brands, J., St Croix, C.M., Kamga, C., Corey, C., Herazo-Maya, J.D., Sembrat, J., Lee, J.S., Duncan, S.R., Rojas, M., Shiva, S., Chu, C.T., Mora, A.L., PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis. J. Clin. Invest. 125 (2015), 521–538.
-
(2015)
J. Clin. Invest.
, vol.125
, pp. 521-538
-
-
Bueno, M.1
Lai, Y.C.2
Romero, Y.3
Brands, J.4
St Croix, C.M.5
Kamga, C.6
Corey, C.7
Herazo-Maya, J.D.8
Sembrat, J.9
Lee, J.S.10
Duncan, S.R.11
Rojas, M.12
Shiva, S.13
Chu, C.T.14
Mora, A.L.15
-
11
-
-
84867271418
-
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis
-
Capparelli, C., Chiavarina, B., Whitaker-Menezes, D., Pestell, T.G., Pestell, R.G., Hulit, J., Ando, S., Howell, A., Martinez-Outschoorn, U.E., Sotgia, F., Lisanti, M.P., CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis. Cell Cycle 11 (2012), 3599–3610.
-
(2012)
Cell Cycle
, vol.11
, pp. 3599-3610
-
-
Capparelli, C.1
Chiavarina, B.2
Whitaker-Menezes, D.3
Pestell, T.G.4
Pestell, R.G.5
Hulit, J.6
Ando, S.7
Howell, A.8
Martinez-Outschoorn, U.E.9
Sotgia, F.10
Lisanti, M.P.11
-
12
-
-
33845892109
-
Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
-
Choudhury, A.R., Ju, Z., Djojosubroto, M.W., Schienke, A., Lechel, A., Schaetzlein, S., Jiang, H., Stepczynska, A., Wang, C., Buer, J., Lee, H.W., Von Zglinicki, T., Ganser, A., Schirmacher, P., Nakauchi, H., Rudolph, K.L., Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation. Nat. Genet. 39 (2007), 99–105.
-
(2007)
Nat. Genet.
, vol.39
, pp. 99-105
-
-
Choudhury, A.R.1
Ju, Z.2
Djojosubroto, M.W.3
Schienke, A.4
Lechel, A.5
Schaetzlein, S.6
Jiang, H.7
Stepczynska, A.8
Wang, C.9
Buer, J.10
Lee, H.W.11
Von Zglinicki, T.12
Ganser, A.13
Schirmacher, P.14
Nakauchi, H.15
Rudolph, K.L.16
-
13
-
-
61649101759
-
Control of OXPHOS efficiency by complex I in brain mitochondria
-
Cocco, T., Pacelli, C., Sgobbo, P., Villani, G., Control of OXPHOS efficiency by complex I in brain mitochondria. Neurobiol. Aging 30 (2009), 622–629.
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 622-629
-
-
Cocco, T.1
Pacelli, C.2
Sgobbo, P.3
Villani, G.4
-
14
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe, J.P., Patil, C.K., Rodier, F., Sun, Y., Munoz, D.P., Goldstein, J., Nelson, P.S., Desprez, P.Y., Campisi, J., Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 6 (2008), 2853–2868.
-
(2008)
PLoS Biol.
, vol.6
, pp. 2853-2868
-
-
Coppe, J.P.1
Patil, C.K.2
Rodier, F.3
Sun, Y.4
Munoz, D.P.5
Goldstein, J.6
Nelson, P.S.7
Desprez, P.Y.8
Campisi, J.9
-
15
-
-
84959065037
-
Mitochondria are required for pro-ageing features of the senescent phenotype
-
Correia-Melo, C., Marques, F.D., Anderson, R., Hewitt, G., Hewitt, R., Cole, J., Carroll, B.M., Miwa, S., Birch, J., Merz, A., Rushton, M.D., Charles, M., Jurk, D., Tait, S.W., Czapiewski, R., Greaves, L., Nelson, G., Bohlooly, Y.M., Rodriguez-Cuenca, S., Vidal-Puig, A., Mann, D., Saretzki, G., Quarato, G., Green, D.R., Adams, P.D., Von Zglinicki, T., Korolchuk, V.I., Passos, J.F., Mitochondria are required for pro-ageing features of the senescent phenotype. EMBO J. 35 (2016), 724–742.
-
(2016)
EMBO J.
, vol.35
, pp. 724-742
-
-
Correia-Melo, C.1
Marques, F.D.2
Anderson, R.3
Hewitt, G.4
Hewitt, R.5
Cole, J.6
Carroll, B.M.7
Miwa, S.8
Birch, J.9
Merz, A.10
Rushton, M.D.11
Charles, M.12
Jurk, D.13
Tait, S.W.14
Czapiewski, R.15
Greaves, L.16
Nelson, G.17
Bohlooly, Y.M.18
Rodriguez-Cuenca, S.19
Vidal-Puig, A.20
Mann, D.21
Saretzki, G.22
Quarato, G.23
Green, D.R.24
Adams, P.D.25
Von Zglinicki, T.26
Korolchuk, V.I.27
Passos, J.F.28
more..
-
16
-
-
84926469999
-
Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions
-
Dalle Pezze, P., Nelson, G., Otten, E.G., Korolchuk, V.I., Kirkwood, T.B., Von Zglinicki, T., Shanley, D.P., Dynamic modelling of pathways to cellular senescence reveals strategies for targeted interventions. PLoS Comput. Biol., 10, 2014, e1003728.
-
(2014)
PLoS Comput. Biol.
, vol.10
-
-
Dalle Pezze, P.1
Nelson, G.2
Otten, E.G.3
Korolchuk, V.I.4
Kirkwood, T.B.5
Von Zglinicki, T.6
Shanley, D.P.7
-
17
-
-
79952693640
-
Mitophagy and Parkinson's disease: the PINK1-parkin link
-
Deas, E., Wood, N.W., Plun-Favreau, H., Mitophagy and Parkinson's disease: the PINK1-parkin link. Biochim. Biophys. Acta 1813 (2011), 623–633.
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 623-633
-
-
Deas, E.1
Wood, N.W.2
Plun-Favreau, H.3
-
18
-
-
85011802318
-
Cellular senescence promotes adverse effects of chemotherapy and cancer relapse
-
Demaria, M., O'leary, M.N., Chang, J., Shao, L., Liu, S., Alimirah, F., Koenig, K., Le, C., Mitin, N., Deal, A.M., Alston, S., Academia, E.C., Kilmarx, S., Valdovinos, A., Wang, B., De Bruin, A., Kennedy, B.K., Melov, S., Zhou, D., Sharpless, N.E., Muss, H., Campisi, J., Cellular senescence promotes adverse effects of chemotherapy and cancer relapse. Cancer Discov. 7 (2017), 165–176.
-
(2017)
Cancer Discov.
, vol.7
, pp. 165-176
-
-
Demaria, M.1
O'leary, M.N.2
Chang, J.3
Shao, L.4
Liu, S.5
Alimirah, F.6
Koenig, K.7
Le, C.8
Mitin, N.9
Deal, A.M.10
Alston, S.11
Academia, E.C.12
Kilmarx, S.13
Valdovinos, A.14
Wang, B.15
De Bruin, A.16
Kennedy, B.K.17
Melov, S.18
Zhou, D.19
Sharpless, N.E.20
Muss, H.21
Campisi, J.22
more..
-
19
-
-
50549087736
-
Growth stimulation leads to cellular senescence when the cell cycle is blocked
-
Demidenko, Z.N., Blagosklonny, M.V., Growth stimulation leads to cellular senescence when the cell cycle is blocked. Cell Cycle 7 (2008), 3355–3361.
-
(2008)
Cell Cycle
, vol.7
, pp. 3355-3361
-
-
Demidenko, Z.N.1
Blagosklonny, M.V.2
-
20
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
Dimri, G.P., Lee, X., Basile, G., Acosta, M., Scott, G., Roskelley, C., Medrano, E.E., Linskens, M., Rubelj, I., Pereira-Smith, O., et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc. Natl. Acad. Sci. U. S. A. 92 (1995), 9363–9367.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
21
-
-
85003441787
-
Robust, universal biomarker assay to detect senescent cells in biological specimens
-
Evangelou, K., Lougiakis, N., Rizou, S., Kotsinas, K., Kletsas, D., Muñoz-Espín, D., Kastrinakis, N.G., Pouli, N., Marakos, P., Townsend, P., Serrano, M., Bartek, J., Gorgoulis, V.G., Robust, universal biomarker assay to detect senescent cells in biological specimens. Aging Cell 16 (2017), 192–197.
-
(2017)
Aging Cell
, vol.16
, pp. 192-197
-
-
Evangelou, K.1
Lougiakis, N.2
Rizou, S.3
Kotsinas, K.4
Kletsas, D.5
Muñoz-Espín, D.6
Kastrinakis, N.G.7
Pouli, N.8
Marakos, P.9
Townsend, P.10
Serrano, M.11
Bartek, J.12
Gorgoulis, V.G.13
-
22
-
-
84997216961
-
Identification of senescent cells in the bone microenvironment
-
Farr, J.N., Fraser, D.G., Wang, H., Jaehn, K., Ogrodnik, M.B., Weivoda, M.M., Drake, M.T., Tchkonia, T., Lebrasseur, N.K., Kirkland, J.L., Bonewald, L.F., Pignolo, R.J., Monroe, D.G., Khosla, S., Identification of senescent cells in the bone microenvironment. J. Bone Miner. Res. 31 (2016), 1920–1929.
-
(2016)
J. Bone Miner. Res.
, vol.31
, pp. 1920-1929
-
-
Farr, J.N.1
Fraser, D.G.2
Wang, H.3
Jaehn, K.4
Ogrodnik, M.B.5
Weivoda, M.M.6
Drake, M.T.7
Tchkonia, T.8
Lebrasseur, N.K.9
Kirkland, J.L.10
Bonewald, L.F.11
Pignolo, R.J.12
Monroe, D.G.13
Khosla, S.14
-
23
-
-
84949550661
-
The metabolic regulation of aging
-
Finkel, T., The metabolic regulation of aging. Nat. Med. 21 (2015), 1416–1423.
-
(2015)
Nat. Med.
, vol.21
, pp. 1416-1423
-
-
Finkel, T.1
-
24
-
-
84919615360
-
Metformin: from mechanisms of action to therapies
-
Foretz, M., Guigas, B., Bertrand, L., Pollak, M., Viollet, B., Metformin: from mechanisms of action to therapies. Cell Metab. 20 (2014), 953–966.
-
(2014)
Cell Metab.
, vol.20
, pp. 953-966
-
-
Foretz, M.1
Guigas, B.2
Bertrand, L.3
Pollak, M.4
Viollet, B.5
-
25
-
-
84953872755
-
Autophagy maintains stemness by preventing senescence
-
Garcia-Prat, L., Martinez-Vicente, M., Perdiguero, E., Ortet, L., Rodriguez-Ubreva, J., Rebollo, E., Ruiz-Bonilla, V., Gutarra, S., Ballestar, E., Serrano, A.L., Sandri, M., Munoz-Canoves, P., Autophagy maintains stemness by preventing senescence. Nature 529 (2016), 37–42.
-
(2016)
Nature
, vol.529
, pp. 37-42
-
-
Garcia-Prat, L.1
Martinez-Vicente, M.2
Perdiguero, E.3
Ortet, L.4
Rodriguez-Ubreva, J.5
Rebollo, E.6
Ruiz-Bonilla, V.7
Gutarra, S.8
Ballestar, E.9
Serrano, A.L.10
Sandri, M.11
Munoz-Canoves, P.12
-
26
-
-
84887581901
-
Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence
-
Hara, H., Araya, J., Ito, S., Kobayashi, K., Takasaka, N., Yoshii, Y., Wakui, H., Kojima, J., Shimizu, K., Numata, T., Kawaishi, M., Kamiya, N., Odaka, M., Morikawa, T., Kaneko, Y., Nakayama, K., Kuwano, K., Mitochondrial fragmentation in cigarette smoke-induced bronchial epithelial cell senescence. Am. J. Phys. Lung Cell. Mol. Phys. 305 (2013), L737–L746.
-
(2013)
Am. J. Phys. Lung Cell. Mol. Phys.
, vol.305
, pp. L737-L746
-
-
Hara, H.1
Araya, J.2
Ito, S.3
Kobayashi, K.4
Takasaka, N.5
Yoshii, Y.6
Wakui, H.7
Kojima, J.8
Shimizu, K.9
Numata, T.10
Kawaishi, M.11
Kamiya, N.12
Odaka, M.13
Morikawa, T.14
Kaneko, Y.15
Nakayama, K.16
Kuwano, K.17
-
27
-
-
85030447786
-
Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex
-
Howell, J.J., Hellberg, K., Turner, M., Talbott, G., Kolar, M.J., Ross, D.S., Hoxhaj, G., Saghatelian, A., Shaw, R.J., Manning, B.D., Metformin inhibits hepatic mTORC1 signaling via dose-dependent mechanisms involving AMPK and the TSC complex. Cell Metab., 2016.
-
(2016)
Cell Metab.
-
-
Howell, J.J.1
Hellberg, K.2
Turner, M.3
Talbott, G.4
Kolar, M.J.5
Ross, D.S.6
Hoxhaj, G.7
Saghatelian, A.8
Shaw, R.J.9
Manning, B.D.10
-
28
-
-
84869186918
-
Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response
-
Jurk, D., Wang, C., Miwa, S., Maddick, M., Korolchuk, V., Tsolou, A., Gonos, E.S., Thrasivoulou, C., Saffrey, M.J., Cameron, K., Von Zglinicki, T., Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response. Aging Cell 11 (2012), 996–1004.
-
(2012)
Aging Cell
, vol.11
, pp. 996-1004
-
-
Jurk, D.1
Wang, C.2
Miwa, S.3
Maddick, M.4
Korolchuk, V.5
Tsolou, A.6
Gonos, E.S.7
Thrasivoulou, C.8
Saffrey, M.J.9
Cameron, K.10
Von Zglinicki, T.11
-
29
-
-
84903485542
-
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
-
Jurk, D., Wilson, C., Passos, J.F., Oakley, F., Correia-Melo, C., Greaves, L., Saretzki, G., Fox, C., Lawless, C., Anderson, R., Hewitt, G., Pender, S.L., Fullard, N., Nelson, G., Mann, J., Van De Sluis, B., Mann, D.A., Von Zglinicki, T., Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat. Commun., 2, 2014, 4172.
-
(2014)
Nat. Commun.
, vol.2
, pp. 4172
-
-
Jurk, D.1
Wilson, C.2
Passos, J.F.3
Oakley, F.4
Correia-Melo, C.5
Greaves, L.6
Saretzki, G.7
Fox, C.8
Lawless, C.9
Anderson, R.10
Hewitt, G.11
Pender, S.L.12
Fullard, N.13
Nelson, G.14
Mann, J.15
Van De Sluis, B.16
Mann, D.A.17
Von Zglinicki, T.18
-
30
-
-
84942456107
-
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
-
Kang, C., Xu, Q., Martin, T.D., Li, M.Z., Demaria, M., Aron, L., Lu, T., Yankner, B.A., Campisi, J., Elledge, S.J., The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4. Science, 349, 2015, aaa 5612.
-
(2015)
Science
, vol.349
-
-
Kang, C.1
Xu, Q.2
Martin, T.D.3
Li, M.Z.4
Demaria, M.5
Aron, L.6
Lu, T.7
Yankner, B.A.8
Campisi, J.9
Elledge, S.J.10
-
31
-
-
79961194820
-
Autophagy impairment induces premature senescence in primary human fibroblasts
-
Kang, H.T., Lee, K.B., Kim, S.Y., Choi, H.R., Park, S.C., Autophagy impairment induces premature senescence in primary human fibroblasts. PLoS One, 6, 2011, e23367.
-
(2011)
PLoS One
, vol.6
-
-
Kang, H.T.1
Lee, K.B.2
Kim, S.Y.3
Choi, H.R.4
Park, S.C.5
-
32
-
-
84878679199
-
A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence
-
Kaplon, J., Zheng, L., Meissl, K., Chaneton, B., Selivanov, V.A., Mackay, G., Van Der Burg, S.H., Verdegaal, E.M., Cascante, M., Shlomi, T., Gottlieb, E., Peeper, D.S., A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence. Nature 498 (2013), 109–112.
-
(2013)
Nature
, vol.498
, pp. 109-112
-
-
Kaplon, J.1
Zheng, L.2
Meissl, K.3
Chaneton, B.4
Selivanov, V.A.5
Mackay, G.6
Van Der Burg, S.H.7
Verdegaal, E.M.8
Cascante, M.9
Shlomi, T.10
Gottlieb, E.11
Peeper, D.S.12
-
33
-
-
84975478637
-
The mechanistic target of rapamycin: the grand ConducTOR of metabolism and aging
-
Kennedy, B.K., Lamming, D.W., The mechanistic target of rapamycin: the grand ConducTOR of metabolism and aging. Cell Metab. 23 (2016), 990–1003.
-
(2016)
Cell Metab.
, vol.23
, pp. 990-1003
-
-
Kennedy, B.K.1
Lamming, D.W.2
-
34
-
-
68849095377
-
Role of mitochondria in photoaging of human skin: the defective powerhouse model
-
Krutmann, J., Schroeder, P., Role of mitochondria in photoaging of human skin: the defective powerhouse model. J. Investig. Dermatol. Symp. Proc. 14 (2009), 44–49.
-
(2009)
J. Investig. Dermatol. Symp. Proc.
, vol.14
, pp. 44-49
-
-
Krutmann, J.1
Schroeder, P.2
-
35
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
Kuilman, T., Michaloglou, C., Vredeveld, L.C., Douma, S., Van Doorn, R., Desmet, C.J., Aarden, L.A., Mooi, W.J., Peeper, D.S., Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell 133 (2008), 1019–1031.
-
(2008)
Cell
, vol.133
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
Douma, S.4
Van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
36
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin, C., Blasco, M.A., Partridge, L., Serrano, M., Kroemer, G., The hallmarks of aging. Cell 153 (2013), 1194–1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
37
-
-
77951199668
-
Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1
-
Mai, S., Klinkenberg, M., Auburger, G., Bereiter-Hahn, J., Jendrach, M., Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1. J. Cell Sci. 123 (2010), 917–926.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 917-926
-
-
Mai, S.1
Klinkenberg, M.2
Auburger, G.3
Bereiter-Hahn, J.4
Jendrach, M.5
-
38
-
-
84856492243
-
Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan
-
Mai, S., Muster, B., Bereiter-Hahn, J., Jendrach, M., Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan. Autophagy 8 (2012), 47–62.
-
(2012)
Autophagy
, vol.8
, pp. 47-62
-
-
Mai, S.1
Muster, B.2
Bereiter-Hahn, J.3
Jendrach, M.4
-
39
-
-
32244448364
-
Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging
-
Mansouri, A., Muller, F.L., Liu, Y., Ng, R., Faulkner, J., Hamilton, M., Richardson, A., Huang, T.T., Epstein, C.J., Van Remmen, H., Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging. Mech. Ageing Dev. 127 (2006), 298–306.
-
(2006)
Mech. Ageing Dev.
, vol.127
, pp. 298-306
-
-
Mansouri, A.1
Muller, F.L.2
Liu, Y.3
Ng, R.4
Faulkner, J.5
Hamilton, M.6
Richardson, A.7
Huang, T.T.8
Epstein, C.J.9
Van Remmen, H.10
-
40
-
-
84900447983
-
Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice
-
Miwa, S., Jow, H., Baty, K., Johnson, A., Czapiewski, R., Saretzki, G., Treumann, A., Von Zglinicki, T., Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice. Nat. Commun., 5, 2014, 3837.
-
(2014)
Nat. Commun.
, vol.5
, pp. 3837
-
-
Miwa, S.1
Jow, H.2
Baty, K.3
Johnson, A.4
Czapiewski, R.5
Saretzki, G.6
Treumann, A.7
Von Zglinicki, T.8
-
41
-
-
68949096538
-
Mitochondrial dysfunction contributes to oncogene-induced senescence
-
Moiseeva, O., Bourdeau, V., Roux, A., Deschenes-Simard, X., Ferbeyre, G., Mitochondrial dysfunction contributes to oncogene-induced senescence. Mol. Cell. Biol. 29 (2009), 4495–4507.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 4495-4507
-
-
Moiseeva, O.1
Bourdeau, V.2
Roux, A.3
Deschenes-Simard, X.4
Ferbeyre, G.5
-
42
-
-
84877822086
-
Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-kappaB activation
-
Moiseeva, O., Deschenes-Simard, X., St-Germain, E., Igelmann, S., Huot, G., Cadar, A.E., Bourdeau, V., Pollak, M.N., Ferbeyre, G., Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-kappaB activation. Aging Cell 12 (2013), 489–498.
-
(2013)
Aging Cell
, vol.12
, pp. 489-498
-
-
Moiseeva, O.1
Deschenes-Simard, X.2
St-Germain, E.3
Igelmann, S.4
Huot, G.5
Cadar, A.E.6
Bourdeau, V.7
Pollak, M.N.8
Ferbeyre, G.9
-
43
-
-
84952838177
-
Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate
-
Mookerjee, S.A., Brand, M.D., Measurement and Analysis of Extracellular Acid Production to Determine Glycolytic Rate. J. Vis. Exp., 2015, e53464.
-
(2015)
J. Vis. Exp.
-
-
Mookerjee, S.A.1
Brand, M.D.2
-
44
-
-
79951642032
-
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
-
Nakahira, K., Haspel, J.A., Rathinam, V.A., Lee, S.J., Dolinay, T., Lam, H.C., Englert, J.A., Rabinovitch, M., Cernadas, M., Kim, H.P., Fitzgerald, K.A., Ryter, S.W., Choi, A.M., Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome. Nat. Immunol. 12 (2011), 222–230.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 222-230
-
-
Nakahira, K.1
Haspel, J.A.2
Rathinam, V.A.3
Lee, S.J.4
Dolinay, T.5
Lam, H.C.6
Englert, J.A.7
Rabinovitch, M.8
Cernadas, M.9
Kim, H.P.10
Fitzgerald, K.A.11
Ryter, S.W.12
Choi, A.M.13
-
45
-
-
79956325949
-
Spatial coupling of mTOR and autophagy augments secretory phenotypes
-
Narita, M., Young, A.R., Arakawa, S., Samarajiwa, S.A., Nakashima, T., Yoshida, S., Hong, S., Berry, L.S., Reichelt, S., Ferreira, M., Tavare, S., Inoki, K., Shimizu, S., Narita, M., Spatial coupling of mTOR and autophagy augments secretory phenotypes. Science 332 (2011), 966–970.
-
(2011)
Science
, vol.332
, pp. 966-970
-
-
Narita, M.1
Young, A.R.2
Arakawa, S.3
Samarajiwa, S.A.4
Nakashima, T.5
Yoshida, S.6
Hong, S.7
Berry, L.S.8
Reichelt, S.9
Ferreira, M.10
Tavare, S.11
Inoki, K.12
Shimizu, S.13
Narita, M.14
-
46
-
-
84862794254
-
A senescent cell bystander effect: senescence-induced senescence
-
Nelson, G., Wordsworth, J., Wang, C., Jurk, D., Lawless, C., Martin-Ruiz, C., Von Zglinicki, T., A senescent cell bystander effect: senescence-induced senescence. Aging Cell 11 (2012), 345–349.
-
(2012)
Aging Cell
, vol.11
, pp. 345-349
-
-
Nelson, G.1
Wordsworth, J.2
Wang, C.3
Jurk, D.4
Lawless, C.5
Martin-Ruiz, C.6
Von Zglinicki, T.7
-
47
-
-
77149164811
-
Feedback between p21 and reactive oxygen production is necessary for cell senescence
-
Passos, J.F., Nelson, G., Wang, C., Richter, T., Simillion, C., Proctor, C.J., Miwa, S., Olijslagers, S., Hallinan, J., Wipat, A., Saretzki, G., Rudolph, K.L., Kirkwood, T.B., Von Zglinicki, T., Feedback between p21 and reactive oxygen production is necessary for cell senescence. Mol. Syst. Biol., 6, 2010, 347.
-
(2010)
Mol. Syst. Biol.
, vol.6
, pp. 347
-
-
Passos, J.F.1
Nelson, G.2
Wang, C.3
Richter, T.4
Simillion, C.5
Proctor, C.J.6
Miwa, S.7
Olijslagers, S.8
Hallinan, J.9
Wipat, A.10
Saretzki, G.11
Rudolph, K.L.12
Kirkwood, T.B.13
Von Zglinicki, T.14
-
48
-
-
34249028642
-
Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence
-
Passos, J.F., Saretzki, G., Ahmed, S., Nelson, G., Richter, T., Peters, H., Wappler, I., Birket, M.J., Harold, G., Schaeuble, K., Birch-Machin, M.A., Kirkwood, T.B., Von Zglinicki, T., Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol., 5, 2007, e110.
-
(2007)
PLoS Biol.
, vol.5
-
-
Passos, J.F.1
Saretzki, G.2
Ahmed, S.3
Nelson, G.4
Richter, T.5
Peters, H.6
Wappler, I.7
Birket, M.J.8
Harold, G.9
Schaeuble, K.10
Birch-Machin, M.A.11
Kirkwood, T.B.12
Von Zglinicki, T.13
-
49
-
-
57449084690
-
Mitochondrial complex I dysfunction in rat heart with aging: critical role of reactive oxygen species and cardiolipin
-
Petrosillo, G., Matera, M., Moro, N., Ruggiero, F.M., Paradies, G., Mitochondrial complex I dysfunction in rat heart with aging: critical role of reactive oxygen species and cardiolipin. Free Radic. Biol. Med. 46 (2009), 88–94.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 88-94
-
-
Petrosillo, G.1
Matera, M.2
Moro, N.3
Ruggiero, F.M.4
Paradies, G.5
-
50
-
-
84938560215
-
Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle
-
Porter, C., Hurren, N.M., Cotter, M.V., Bhattarai, N., Reidy, P.T., Dillon, E.L., Durham, W.J., Tuvdendorj, D., Sheffield-Moore, M., Volpi, E., Sidossis, L.S., Rasmussen, B.B., Borsheim, E., Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 309 (2015), E224–E232.
-
(2015)
Am. J. Physiol. Endocrinol. Metab.
, vol.309
, pp. E224-E232
-
-
Porter, C.1
Hurren, N.M.2
Cotter, M.V.3
Bhattarai, N.4
Reidy, P.T.5
Dillon, E.L.6
Durham, W.J.7
Tuvdendorj, D.8
Sheffield-Moore, M.9
Volpi, E.10
Sidossis, L.S.11
Rasmussen, B.B.12
Borsheim, E.13
-
51
-
-
79955957226
-
Collagen fragments inhibit hyaluronan synthesis in skin fibroblasts in response to ultraviolet B (UVB): new insights into mechanisms of matrix remodeling
-
Rock, K., Grandoch, M., Majora, M., Krutmann, J., Fischer, J.W., Collagen fragments inhibit hyaluronan synthesis in skin fibroblasts in response to ultraviolet B (UVB): new insights into mechanisms of matrix remodeling. J. Biol. Chem. 286 (2011), 18268–18276.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 18268-18276
-
-
Rock, K.1
Grandoch, M.2
Majora, M.3
Krutmann, J.4
Fischer, J.W.5
-
52
-
-
80052303130
-
Autophagy and aging
-
Rubinsztein, D.C., Marino, G., Kroemer, G., Autophagy and aging. Cell 146 (2011), 682–695.
-
(2011)
Cell
, vol.146
, pp. 682-695
-
-
Rubinsztein, D.C.1
Marino, G.2
Kroemer, G.3
-
53
-
-
79951812916
-
Telomere dysfunction induces metabolic and mitochondrial compromise
-
Sahin, E., Colla, S., Liesa, M., Moslehi, J., Muller, F.L., Guo, M., Cooper, M., Kotton, D., Fabian, A.J., Walkey, C., Maser, R.S., Tonon, G., Foerster, F., Xiong, R., Wang, Y.A., Shukla, S.A., Jaskelioff, M., Martin, E.S., Heffernan, T.P., Protopopov, A., Ivanova, E., Mahoney, J.E., Kost-Alimova, M., Perry, S.R., Bronson, R., Liao, R., Mulligan, R., Shirihai, O.S., Chin, L., Depinho, R.A., Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 470 (2011), 359–365.
-
(2011)
Nature
, vol.470
, pp. 359-365
-
-
Sahin, E.1
Colla, S.2
Liesa, M.3
Moslehi, J.4
Muller, F.L.5
Guo, M.6
Cooper, M.7
Kotton, D.8
Fabian, A.J.9
Walkey, C.10
Maser, R.S.11
Tonon, G.12
Foerster, F.13
Xiong, R.14
Wang, Y.A.15
Shukla, S.A.16
Jaskelioff, M.17
Martin, E.S.18
Heffernan, T.P.19
Protopopov, A.20
Ivanova, E.21
Mahoney, J.E.22
Kost-Alimova, M.23
Perry, S.R.24
Bronson, R.25
Liao, R.26
Mulligan, R.27
Shirihai, O.S.28
Chin, L.29
Depinho, R.A.30
more..
-
54
-
-
84942115958
-
Metformin and inflammation: its potential beyond glucose-lowering effect
-
Saisho, Y., Metformin and inflammation: its potential beyond glucose-lowering effect. Endocr Metab Immune Disord Drug Targets 15 (2015), 196–205.
-
(2015)
Endocr Metab Immune Disord Drug Targets
, vol.15
, pp. 196-205
-
-
Saisho, Y.1
-
55
-
-
84863329778
-
Inflammaging: disturbed interplay between autophagy and inflammasomes
-
Salminen, A., Kaarniranta, K., Kauppinen, A., Inflammaging: disturbed interplay between autophagy and inflammasomes. Aging (Albany NY) 4 (2012), 166–175.
-
(2012)
Aging (Albany NY)
, vol.4
, pp. 166-175
-
-
Salminen, A.1
Kaarniranta, K.2
Kauppinen, A.3
-
56
-
-
84969872759
-
Exercise prevents diet-induced cellular senescence in adipose tissue
-
Schafer, M.J., White, T.A., Evans, G., Tonne, J.M., Verzosa, G.C., Stout, M.B., Mazula, D.L., Palmer, A.K., Baker, D.J., Jensen, M.D., Torbenson, M.S., Miller, J.D., Ikeda, Y., Tchkonia, T., Van Deursen, J.M., Kirkland, J.L., Lebrasseur, N.K., Exercise prevents diet-induced cellular senescence in adipose tissue. Diabetes 65 (2016), 1606–1615.
-
(2016)
Diabetes
, vol.65
, pp. 1606-1615
-
-
Schafer, M.J.1
White, T.A.2
Evans, G.3
Tonne, J.M.4
Verzosa, G.C.5
Stout, M.B.6
Mazula, D.L.7
Palmer, A.K.8
Baker, D.J.9
Jensen, M.D.10
Torbenson, M.S.11
Miller, J.D.12
Ikeda, Y.13
Tchkonia, T.14
Van Deursen, J.M.15
Kirkland, J.L.16
Lebrasseur, N.K.17
-
57
-
-
84857289515
-
Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress
-
Singh, K., Matsuyama, S., Drazba, J.A., Almasan, A., Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress. Autophagy 8 (2012), 236–251.
-
(2012)
Autophagy
, vol.8
, pp. 236-251
-
-
Singh, K.1
Matsuyama, S.2
Drazba, J.A.3
Almasan, A.4
-
58
-
-
0035092972
-
Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress
-
Sitte, N., Merker, K., Grune, T., Von Zglinicki, T., Lipofuscin accumulation in proliferating fibroblasts in vitro: an indicator of oxidative stress. Exp. Gerontol. 36 (2001), 475–486.
-
(2001)
Exp. Gerontol.
, vol.36
, pp. 475-486
-
-
Sitte, N.1
Merker, K.2
Grune, T.3
Von Zglinicki, T.4
-
59
-
-
84921911209
-
The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro
-
Spilsbury, A., Miwa, S., Attems, J., Saretzki, G., The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro. J. Neurosci. 35 (2015), 1659–1674.
-
(2015)
J. Neurosci.
, vol.35
, pp. 1659-1674
-
-
Spilsbury, A.1
Miwa, S.2
Attems, J.3
Saretzki, G.4
-
60
-
-
85005978336
-
Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty
-
Stout, M.B., Justice, J.N., Nicklas, B.J., Kirkland, J.L., Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty. Physiology (Bethesda) 32 (2017), 9–19.
-
(2017)
Physiology (Bethesda)
, vol.32
, pp. 9-19
-
-
Stout, M.B.1
Justice, J.N.2
Nicklas, B.J.3
Kirkland, J.L.4
-
61
-
-
84996598519
-
Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence
-
Tai, H., Wang, Z., Gong, H., Han, X., Zhou, J., Wang, X., Wei, X., Ding, Y., Huang, N., Qin, J., Zhang, J., Wang, S., Gao, F., Chrzanowska-Lightowlers, Z.M., Xiang, R., Xiao, H., Autophagy impairment with lysosomal and mitochondrial dysfunction is an important characteristic of oxidative stress-induced senescence. Autophagy 13 (2017), 99–113.
-
(2017)
Autophagy
, vol.13
, pp. 99-113
-
-
Tai, H.1
Wang, Z.2
Gong, H.3
Han, X.4
Zhou, J.5
Wang, X.6
Wei, X.7
Ding, Y.8
Huang, N.9
Qin, J.10
Zhang, J.11
Wang, S.12
Gao, F.13
Chrzanowska-Lightowlers, Z.M.14
Xiang, R.15
Xiao, H.16
-
62
-
-
84880508209
-
High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat
-
Tian, X., Azpurua, J., Hine, C., Vaidya, A., Myakishev-Rempel, M., Ablaeva, J., Mao, Z., Nevo, E., Gorbunova, V., Seluanov, A., High-molecular-mass hyaluronan mediates the cancer resistance of the naked mole rat. Nature 499 (2013), 346–349.
-
(2013)
Nature
, vol.499
, pp. 346-349
-
-
Tian, X.1
Azpurua, J.2
Hine, C.3
Vaidya, A.4
Myakishev-Rempel, M.5
Ablaeva, J.6
Mao, Z.7
Nevo, E.8
Gorbunova, V.9
Seluanov, A.10
-
63
-
-
66149167336
-
DNA damage response and cellular senescence in tissues of aging mice
-
Wang, C., Jurk, D., Maddick, M., Nelson, G., Martin-Ruiz, C., Von Zglinicki, T., DNA damage response and cellular senescence in tissues of aging mice. Aging Cell 8 (2009), 311–323.
-
(2009)
Aging Cell
, vol.8
, pp. 311-323
-
-
Wang, C.1
Jurk, D.2
Maddick, M.3
Nelson, G.4
Martin-Ruiz, C.5
Von Zglinicki, T.6
-
64
-
-
79952118049
-
Adult-onset, short-term dietary restriction reduces cell senescence in mice
-
Wang, C., Maddick, M., Miwa, S., Jurk, D., Czapiewski, R., Saretzki, G., Langie, S.A., Godschalk, R.W., Cameron, K., Von Zglinicki, T., Adult-onset, short-term dietary restriction reduces cell senescence in mice. Aging (Albany NY) 2 (2010), 555–566.
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 555-566
-
-
Wang, C.1
Maddick, M.2
Miwa, S.3
Jurk, D.4
Czapiewski, R.5
Saretzki, G.6
Langie, S.A.7
Godschalk, R.W.8
Cameron, K.9
Von Zglinicki, T.10
-
65
-
-
84948953210
-
Mitochondrial dysfunction and longevity in animals: untangling the knot
-
Wang, Y., Hekimi, S., Mitochondrial dysfunction and longevity in animals: untangling the knot. Science 350 (2015), 1204–1207.
-
(2015)
Science
, vol.350
, pp. 1204-1207
-
-
Wang, Y.1
Hekimi, S.2
-
66
-
-
84865191462
-
Autophagic activity dictates the cellular response to oncogenic RAS
-
Wang, Y., Wang, X.D., Lapi, E., Sullivan, A., Jia, W., He, Y.W., Ratnayaka, I., Zhong, S., Goldin, R.D., Goemans, C.G., Tolkovsky, A.M., Lu, X., Autophagic activity dictates the cellular response to oncogenic RAS. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 13325–13330.
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 13325-13330
-
-
Wang, Y.1
Wang, X.D.2
Lapi, E.3
Sullivan, A.4
Jia, W.5
He, Y.W.6
Ratnayaka, I.7
Zhong, S.8
Goldin, R.D.9
Goemans, C.G.10
Tolkovsky, A.M.11
Lu, X.12
-
67
-
-
84957952429
-
Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
-
Wiley, C.D., Velarde, M.C., Lecot, P., Liu, S., Sarnoski, E.A., Freund, A., Shirakawa, K., Lim, H.W., Davis, S.S., Ramanathan, A., Gerencser, A.A., Verdin, E., Campisi, J., Mitochondrial dysfunction induces senescence with a distinct secretory phenotype. Cell Metab. 23 (2016), 303–314.
-
(2016)
Cell Metab.
, vol.23
, pp. 303-314
-
-
Wiley, C.D.1
Velarde, M.C.2
Lecot, P.3
Liu, S.4
Sarnoski, E.A.5
Freund, A.6
Shirakawa, K.7
Lim, H.W.8
Davis, S.S.9
Ramanathan, A.10
Gerencser, A.A.11
Verdin, E.12
Campisi, J.13
-
68
-
-
84988603034
-
Targeting senescent cells enhances adipogenesis and metabolic function in old age
-
Xu, M., Palmer, A.K., Ding, H., Weivoda, M.M., Pirtskhalava, T., White, T.A., Sepe, A., Johnson, K.O., Stout, M.B., Giorgadze, N., Jensen, M.D., Lebrasseur, N.K., Tchkonia, T., Kirkland, J.L., Targeting senescent cells enhances adipogenesis and metabolic function in old age. elife, 4, 2015, e12997.
-
(2015)
elife
, vol.4
-
-
Xu, M.1
Palmer, A.K.2
Ding, H.3
Weivoda, M.M.4
Pirtskhalava, T.5
White, T.A.6
Sepe, A.7
Johnson, K.O.8
Stout, M.B.9
Giorgadze, N.10
Jensen, M.D.11
Lebrasseur, N.K.12
Tchkonia, T.13
Kirkland, J.L.14
-
69
-
-
64349123107
-
Autophagy mediates the mitotic senescence transition
-
Young, A.R., Narita, M., Ferreira, M., Kirschner, K., Sadaie, M., Darot, J.F., Tavare, S., Arakawa, S., Shimizu, S., Watt, F.M., Narita, M., Autophagy mediates the mitotic senescence transition. Genes Dev. 23 (2009), 798–803.
-
(2009)
Genes Dev.
, vol.23
, pp. 798-803
-
-
Young, A.R.1
Narita, M.2
Ferreira, M.3
Kirschner, K.4
Sadaie, M.5
Darot, J.F.6
Tavare, S.7
Arakawa, S.8
Shimizu, S.9
Watt, F.M.10
Narita, M.11
-
70
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou, R., Yazdi, A.S., Menu, P., Tschopp, J., A role for mitochondria in NLRP3 inflammasome activation. Nature 469 (2011), 221–225.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
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