Low abundance of the matrix arm of complex I in mitochondria predicts longevity in mice

Nature Communications

Volumn 5, Issue , 2014, Pages

  Miwa, Satomi ^a   Jow, Howsun ^b   Baty, Karen ^b   Johnson, Amy ^a   Czapiewski, Rafal ^a   Saretzki, Gabriele ^a   Treumann, Achim ^b   Von Zglinicki, Thomas ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROHIBITIN; PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE; NDUFB9 PROTEIN, HUMAN; NDUFS3 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REPRESSOR PROTEIN; SMALL INTERFERING RNA;

AGING; CATALYSIS; LONGEVITY; MITOCHONDRION; OXYGEN CONSUMPTION; PROTEIN; RODENT; SUBSTRATE;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN MITOCHONDRION; CELL AGING; CELL FUNCTION; CELL GROWTH; CONTROLLED STUDY; LIVER MITOCHONDRION; LONGEVITY; MALE; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PROTEOMICS; RESPIRATION CONTROL; RESPIRATORY CHAIN; SENESCENCE; SIGNAL TRANSDUCTION; AGING; ANIMAL; C57BL MOUSE; CELL LINE; GENETICS; HELA CELL LINE; HUMAN; LIVER; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHYSIOLOGY; PREMATURE AGING; RNA INTERFERENCE; TRANSGENIC MOUSE;

AGING; AGING, PREMATURE; ANIMALS; CELL LINE; ELECTRON TRANSPORT COMPLEX I; HELA CELLS; HUMANS; LIVER; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; NADH DEHYDROGENASE; OXIDATION-REDUCTION; OXIDATIVE STRESS; PROTEOMICS; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84900447983     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms4837     Document Type: Article

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