-
1
-
-
85020881220
-
Hansemann's Ideas of the Nature of Cancer: Description and Analysis, David Paul Von Hansemann: Contributions to Oncology, Birkhäuser, Basel
-
Bignold, L.P., Coghlan, B.L.D., Jersmann, H.P.A., Hansemann's Ideas of the Nature of Cancer: Description and Analysis, David Paul Von Hansemann: Contributions to Oncology, Birkhäuser, Basel. 2007, 75–90.
-
(2007)
, pp. 75-90
-
-
Bignold, L.P.1
Coghlan, B.L.D.2
Jersmann, H.P.A.3
-
2
-
-
0033119762
-
Intratumor heterogeneity of chromosome 1, 7, 17, and 18 aneusomies obtained by FISH and association with flow cytometric DNA index in human colorectal adenocarcinomas
-
Di Vinci, A., Infusini, E., Peveri, C., Sciutto, A., Orecchia, R., Geido, E., Monaco, R., Giaretti, W., Intratumor heterogeneity of chromosome 1, 7, 17, and 18 aneusomies obtained by FISH and association with flow cytometric DNA index in human colorectal adenocarcinomas. Cytometry 35 (1999), 369–375.
-
(1999)
Cytometry
, vol.35
, pp. 369-375
-
-
Di Vinci, A.1
Infusini, E.2
Peveri, C.3
Sciutto, A.4
Orecchia, R.5
Geido, E.6
Monaco, R.7
Giaretti, W.8
-
3
-
-
0028848397
-
HER-2 overexpression, and intratumor heterogeneity in human breast cancer
-
HER-2 overexpression, and intratumor heterogeneity in human breast cancer. Cancer Res. 55 (1995), 5400–5407.
-
(1995)
Cancer Res.
, vol.55
, pp. 5400-5407
-
-
Szollosi, J.1
Balazs, M.2
Feuerstein, B.G.3
Benz, C.C.4
Waldman, F.M.5
-
4
-
-
0035864901
-
Clone heterogeneity in diploid and aneuploid breast carcinomas as detected by FISH
-
Farabegoli, F., Santini, D., Ceccarelli, C., Taffurelli, M., Marrano, D., Baldini, N., Clone heterogeneity in diploid and aneuploid breast carcinomas as detected by FISH. Cytometry 46 (2001), 50–56.
-
(2001)
Cytometry
, vol.46
, pp. 50-56
-
-
Farabegoli, F.1
Santini, D.2
Ceccarelli, C.3
Taffurelli, M.4
Marrano, D.5
Baldini, N.6
-
5
-
-
35348853238
-
DNA microarrays: a powerful genomic tool for biomedical and clinical research
-
Trevino, V., Falciani, F., Barrera-Saldana, H.A., DNA microarrays: a powerful genomic tool for biomedical and clinical research. Mol. Med. 13 (2007), 527–541.
-
(2007)
Mol. Med.
, vol.13
, pp. 527-541
-
-
Trevino, V.1
Falciani, F.2
Barrera-Saldana, H.A.3
-
6
-
-
77956838065
-
Advances in understanding cancer genomes through second-generation sequencing
-
Meyerson, M., Gabriel, S., Getz, G., Advances in understanding cancer genomes through second-generation sequencing. Nat. Rev. Genet. 11 (2010), 685–696.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 685-696
-
-
Meyerson, M.1
Gabriel, S.2
Getz, G.3
-
7
-
-
79951475133
-
A decade's perspective on DNA sequencing technology
-
Mardis, E.R., A decade's perspective on DNA sequencing technology. Nature 470 (2011), 198–203.
-
(2011)
Nature
, vol.470
, pp. 198-203
-
-
Mardis, E.R.1
-
9
-
-
84938799837
-
Toward understanding and exploiting tumor heterogeneity
-
Alizadeh, A.A., Aranda, V., Bardelli, A., Blanpain, C., Bock, C., Borowski, C., Caldas, C., Califano, A., Doherty, M., Elsner, M., Esteller, M., Fitzgerald, R., Korbel, J.O., Lichter, P., Mason, C.E., Navin, N., Pe'er, D., Polyak, K., Roberts, C.W., Siu, L., Snyder, A., Stower, H., Swanton, C., Verhaak, R.G., Zenklusen, J.C., Zuber, J., Zucman-Rossi, J., Toward understanding and exploiting tumor heterogeneity. Nat. Med. 21 (2015), 846–853.
-
(2015)
Nat. Med.
, vol.21
, pp. 846-853
-
-
Alizadeh, A.A.1
Aranda, V.2
Bardelli, A.3
Blanpain, C.4
Bock, C.5
Borowski, C.6
Caldas, C.7
Califano, A.8
Doherty, M.9
Elsner, M.10
Esteller, M.11
Fitzgerald, R.12
Korbel, J.O.13
Lichter, P.14
Mason, C.E.15
Navin, N.16
Pe'er, D.17
Polyak, K.18
Roberts, C.W.19
Siu, L.20
Snyder, A.21
Stower, H.22
Swanton, C.23
Verhaak, R.G.24
Zenklusen, J.C.25
Zuber, J.26
Zucman-Rossi, J.27
more..
-
10
-
-
78649251520
-
The origins and implications of intratumor heterogeneity
-
Michor, F., Polyak, K., The origins and implications of intratumor heterogeneity. Cancer Prev. Res. 3 (2010), 1361–1364.
-
(2010)
Cancer Prev. Res.
, vol.3
, pp. 1361-1364
-
-
Michor, F.1
Polyak, K.2
-
11
-
-
84856013431
-
Clonal evolution in cancer
-
Greaves, M., Maley, C.C., Clonal evolution in cancer. Nature 481 (2012), 306–313.
-
(2012)
Nature
, vol.481
, pp. 306-313
-
-
Greaves, M.1
Maley, C.C.2
-
12
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell, P., The clonal evolution of tumor cell populations. Science 194 (1976), 23–28.
-
(1976)
Science
, vol.194
, pp. 23-28
-
-
Nowell, P.1
-
13
-
-
0018141482
-
Tumor heterogeneity and the biology of cancer invasion and metastasis
-
Fidler, I.J., Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res. 38 (1978), 2651–2660.
-
(1978)
Cancer Res.
, vol.38
, pp. 2651-2660
-
-
Fidler, I.J.1
-
14
-
-
33845243362
-
Cancer as an evolutionary and ecological process
-
Merlo, L.M.F., Pepper, J.W., Reid, B.J., Maley, C.C., Cancer as an evolutionary and ecological process. Nat. Rev. Cancer 6 (2006), 924–935.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 924-935
-
-
Merlo, L.M.F.1
Pepper, J.W.2
Reid, B.J.3
Maley, C.C.4
-
15
-
-
84933178115
-
Concepts in solid tumor evolution
-
Sidow, A., Spies, N., Concepts in solid tumor evolution. Trends Genet. 31 (2015), 208–214.
-
(2015)
Trends Genet.
, vol.31
, pp. 208-214
-
-
Sidow, A.1
Spies, N.2
-
16
-
-
77953870937
-
Tracing the tumor lineage
-
Navin, N.E., Hicks, J., Tracing the tumor lineage. Mol. Oncol. 4 (2010), 267–283.
-
(2010)
Mol. Oncol.
, vol.4
, pp. 267-283
-
-
Navin, N.E.1
Hicks, J.2
-
17
-
-
84861550476
-
The life history of 21 breast cancers
-
Nik-Zainal, S., Van Loo, P., Wedge, D.C., Alexandrov, L.B., Greenman, C.D., Lau, K.W., Raine, K., Jones, D., Marshall, J., Ramakrishna, M., Shlien, A., Cooke, S.L., Hinton, J., Menzies, A., Stebbings, L.A., Leroy, C., Jia, M., Rance, R., Mudie, L.J., Gamble, S.J., Stephens, P.J., McLaren, S., Tarpey, P.S., Papaemmanuil, E., Davies, H.R., Varela, I., McBride, D.J., Bignell, G.R., Leung, K., Butler, A.P., Teague, J.W., Martin, S., Jonsson, G., Mariani, O., Boyault, S., Miron, P., Fatima, A., Langerod, A., Aparicio, S.A., Tutt, A., Sieuwerts, A.M., Borg, A., Thomas, G., Salomon, A.V., Richardson, A.L., Borresen-Dale, A.L., Futreal, P.A., Stratton, M.R., Campbell, P.J., The life history of 21 breast cancers. Cell 149 (2012), 994–1007.
-
(2012)
Cell
, vol.149
, pp. 994-1007
-
-
Nik-Zainal, S.1
Van Loo, P.2
Wedge, D.C.3
Alexandrov, L.B.4
Greenman, C.D.5
Lau, K.W.6
Raine, K.7
Jones, D.8
Marshall, J.9
Ramakrishna, M.10
Shlien, A.11
Cooke, S.L.12
Hinton, J.13
Menzies, A.14
Stebbings, L.A.15
Leroy, C.16
Jia, M.17
Rance, R.18
Mudie, L.J.19
Gamble, S.J.20
Stephens, P.J.21
McLaren, S.22
Tarpey, P.S.23
Papaemmanuil, E.24
Davies, H.R.25
Varela, I.26
McBride, D.J.27
Bignell, G.R.28
Leung, K.29
Butler, A.P.30
Teague, J.W.31
Martin, S.32
Jonsson, G.33
Mariani, O.34
Boyault, S.35
Miron, P.36
Fatima, A.37
Langerod, A.38
Aparicio, S.A.39
Tutt, A.40
Sieuwerts, A.M.41
Borg, A.42
Thomas, G.43
Salomon, A.V.44
Richardson, A.L.45
Borresen-Dale, A.L.46
Futreal, P.A.47
Stratton, M.R.48
Campbell, P.J.49
more..
-
18
-
-
84862526929
-
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
-
Shah, S.P., Roth, A., Goya, R., Oloumi, A., Ha, G., Zhao, Y., Turashvili, G., Ding, J., Tse, K., Haffari, G., Bashashati, A., Prentice, L.M., Khattra, J., Burleigh, A., Yap, D., Bernard, V., McPherson, A., Shumansky, K., Crisan, A., Giuliany, R., Heravi-Moussavi, A., Rosner, J., Lai, D., Birol, I., Varhol, R., Tam, A., Dhalla, N., Zeng, T., Ma, K., Chan, S.K., Griffith, M., Moradian, A., Cheng, S.W., Morin, G.B., Watson, P., Gelmon, K., Chia, S., Chin, S.F., Curtis, C., Rueda, O.M., Pharoah, P.D., Damaraju, S., Mackey, J., Hoon, K., Harkins, T., Tadigotla, V., Sigaroudinia, M., Gascard, P., Tlsty, T., Costello, J.F., Meyer, I.M., Eaves, C.J., Wasserman, W.W., Jones, S., Huntsman, D., Hirst, M., Caldas, C., Marra, M.A., Aparicio, S., The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature 486 (2012), 395–399.
-
(2012)
Nature
, vol.486
, pp. 395-399
-
-
Shah, S.P.1
Roth, A.2
Goya, R.3
Oloumi, A.4
Ha, G.5
Zhao, Y.6
Turashvili, G.7
Ding, J.8
Tse, K.9
Haffari, G.10
Bashashati, A.11
Prentice, L.M.12
Khattra, J.13
Burleigh, A.14
Yap, D.15
Bernard, V.16
McPherson, A.17
Shumansky, K.18
Crisan, A.19
Giuliany, R.20
Heravi-Moussavi, A.21
Rosner, J.22
Lai, D.23
Birol, I.24
Varhol, R.25
Tam, A.26
Dhalla, N.27
Zeng, T.28
Ma, K.29
Chan, S.K.30
Griffith, M.31
Moradian, A.32
Cheng, S.W.33
Morin, G.B.34
Watson, P.35
Gelmon, K.36
Chia, S.37
Chin, S.F.38
Curtis, C.39
Rueda, O.M.40
Pharoah, P.D.41
Damaraju, S.42
Mackey, J.43
Hoon, K.44
Harkins, T.45
Tadigotla, V.46
Sigaroudinia, M.47
Gascard, P.48
Tlsty, T.49
Costello, J.F.50
Meyer, I.M.51
Eaves, C.J.52
Wasserman, W.W.53
Jones, S.54
Huntsman, D.55
Hirst, M.56
Caldas, C.57
Marra, M.A.58
Aparicio, S.59
more..
-
19
-
-
84952310964
-
SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution
-
Miller, C.A., White, B.S., Dees, N.D., Griffith, M., Welch, J.S., Griffith, O.L., Vij, R., Tomasson, M.H., Graubert, T.A., Walter, M.J., Ellis, M.J., Schierding, W., DiPersio, J.F., Ley, T.J., Mardis, E.R., Wilson, R.K., Ding, L., SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution. PLoS Comput. Biol., 10, 2014, e1003665.
-
(2014)
PLoS Comput. Biol.
, vol.10
-
-
Miller, C.A.1
White, B.S.2
Dees, N.D.3
Griffith, M.4
Welch, J.S.5
Griffith, O.L.6
Vij, R.7
Tomasson, M.H.8
Graubert, T.A.9
Walter, M.J.10
Ellis, M.J.11
Schierding, W.12
DiPersio, J.F.13
Ley, T.J.14
Mardis, E.R.15
Wilson, R.K.16
Ding, L.17
-
20
-
-
84897954204
-
PyClone: statistical inference of clonal population structure in cancer
-
Roth, A., Khattra, J., Yap, D., Wan, A., Laks, E., Biele, J., Ha, G., Aparicio, S., Bouchard-Cote, A., Shah, S.P., PyClone: statistical inference of clonal population structure in cancer. Nat. Methods 11 (2014), 396–398.
-
(2014)
Nat. Methods
, vol.11
, pp. 396-398
-
-
Roth, A.1
Khattra, J.2
Yap, D.3
Wan, A.4
Laks, E.5
Biele, J.6
Ha, G.7
Aparicio, S.8
Bouchard-Cote, A.9
Shah, S.P.10
-
21
-
-
84895876130
-
Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
-
Gerlinger, M., Horswell, S., Larkin, J., Rowan, A.J., Salm, M.P., Varela, I., Fisher, R., McGranahan, N., Matthews, N., Santos, C.R., Martinez, P., Phillimore, B., Begum, S., Rabinowitz, A., Spencer-Dene, B., Gulati, S., Bates, P.A., Stamp, G., Pickering, L., Gore, M., Nicol, D.L., Hazell, S., Futreal, P.A., Stewart, A., Swanton, C., Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing. Nat. Genet. 46 (2014), 225–233.
-
(2014)
Nat. Genet.
, vol.46
, pp. 225-233
-
-
Gerlinger, M.1
Horswell, S.2
Larkin, J.3
Rowan, A.J.4
Salm, M.P.5
Varela, I.6
Fisher, R.7
McGranahan, N.8
Matthews, N.9
Santos, C.R.10
Martinez, P.11
Phillimore, B.12
Begum, S.13
Rabinowitz, A.14
Spencer-Dene, B.15
Gulati, S.16
Bates, P.A.17
Stamp, G.18
Pickering, L.19
Gore, M.20
Nicol, D.L.21
Hazell, S.22
Futreal, P.A.23
Stewart, A.24
Swanton, C.25
more..
-
22
-
-
84907808265
-
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
-
Zhang, J., Fujimoto, J., Zhang, J., Wedge, D.C., Song, X., Zhang, J., Seth, S., Chow, C.W., Cao, Y., Gumbs, C., Gold, K.A., Kalhor, N., Little, L., Mahadeshwar, H., Moran, C., Protopopov, A., Sun, H., Tang, J., Wu, X., Ye, Y., William, W.N., Lee, J.J., Heymach, J.V., Hong, W.K., Swisher, S., Wistuba, I.I., Futreal, P.A., Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing. Science 346 (2014), 256–259.
-
(2014)
Science
, vol.346
, pp. 256-259
-
-
Zhang, J.1
Fujimoto, J.2
Zhang, J.3
Wedge, D.C.4
Song, X.5
Zhang, J.6
Seth, S.7
Chow, C.W.8
Cao, Y.9
Gumbs, C.10
Gold, K.A.11
Kalhor, N.12
Little, L.13
Mahadeshwar, H.14
Moran, C.15
Protopopov, A.16
Sun, H.17
Tang, J.18
Wu, X.19
Ye, Y.20
William, W.N.21
Lee, J.J.22
Heymach, J.V.23
Hong, W.K.24
Swisher, S.25
Wistuba, I.I.26
Futreal, P.A.27
more..
-
23
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger, M., Rowan, A.J., Horswell, S., Larkin, J., Endesfelder, D., Gronroos, E., Martinez, P., Matthews, N., Stewart, A., Tarpey, P., Varela, I., Phillimore, B., Begum, S., McDonald, N.Q., Butler, A., Jones, D., Raine, K., Latimer, C., Santos, C.R., Nohadani, M., Eklund, A.C., Spencer-Dene, B., Clark, G., Pickering, L., Stamp, G., Gore, M., Szallasi, Z., Downward, J., Futreal, P.A., Swanton, C., Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N. Engl. J. Med. 366 (2012), 883–892.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
Martinez, P.7
Matthews, N.8
Stewart, A.9
Tarpey, P.10
Varela, I.11
Phillimore, B.12
Begum, S.13
McDonald, N.Q.14
Butler, A.15
Jones, D.16
Raine, K.17
Latimer, C.18
Santos, C.R.19
Nohadani, M.20
Eklund, A.C.21
Spencer-Dene, B.22
Clark, G.23
Pickering, L.24
Stamp, G.25
Gore, M.26
Szallasi, Z.27
Downward, J.28
Futreal, P.A.29
Swanton, C.30
more..
-
24
-
-
84968547900
-
Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer
-
McPherson, A., Roth, A., Laks, E., Masud, T., Bashashati, A., Zhang, A.W., Ha, G., Biele, J., Yap, D., Wan, A., Prentice, L.M., Khattra, J., Smith, M.A., Nielsen, C.B., Mullaly, S.C., Kalloger, S., Karnezis, A., Shumansky, K., Siu, C., Rosner, J., Chan, H.L., Ho, J., Melnyk, N., Senz, J., Yang, W., Moore, R., Mungall, A.J., Marra, M.A., Bouchard-Cote, A., Gilks, C.B., Huntsman, D.G., McAlpine, J.N., Aparicio, S., Shah, S.P., Divergent modes of clonal spread and intraperitoneal mixing in high-grade serous ovarian cancer. Nat. Genet., 2016.
-
(2016)
Nat. Genet.
-
-
McPherson, A.1
Roth, A.2
Laks, E.3
Masud, T.4
Bashashati, A.5
Zhang, A.W.6
Ha, G.7
Biele, J.8
Yap, D.9
Wan, A.10
Prentice, L.M.11
Khattra, J.12
Smith, M.A.13
Nielsen, C.B.14
Mullaly, S.C.15
Kalloger, S.16
Karnezis, A.17
Shumansky, K.18
Siu, C.19
Rosner, J.20
Chan, H.L.21
Ho, J.22
Melnyk, N.23
Senz, J.24
Yang, W.25
Moore, R.26
Mungall, A.J.27
Marra, M.A.28
Bouchard-Cote, A.29
Gilks, C.B.30
Huntsman, D.G.31
McAlpine, J.N.32
Aparicio, S.33
Shah, S.P.34
more..
-
25
-
-
79953766940
-
Tumour evolution inferred by single-cell sequencing
-
Navin, N., Kendall, J., Troge, J., Andrews, P., Rodgers, L., McIndoo, J., Cook, K., Stepansky, A., Levy, D., Esposito, D., Muthuswamy, L., Krasnitz, A., McCombie, W.R., Hicks, J., Wigler, M., Tumour evolution inferred by single-cell sequencing. Nature 472 (2011), 90–94.
-
(2011)
Nature
, vol.472
, pp. 90-94
-
-
Navin, N.1
Kendall, J.2
Troge, J.3
Andrews, P.4
Rodgers, L.5
McIndoo, J.6
Cook, K.7
Stepansky, A.8
Levy, D.9
Esposito, D.10
Muthuswamy, L.11
Krasnitz, A.12
McCombie, W.R.13
Hicks, J.14
Wigler, M.15
-
26
-
-
84863230091
-
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor
-
Xu, X., Hou, Y., Yin, X., Bao, L., Tang, A., Song, L., Li, F., Tsang, S., Wu, K., Wu, H., He, W., Zeng, L., Xing, M., Wu, R., Jiang, H., Liu, X., Cao, D., Guo, G., Hu, X., Gui, Y., Li, Z., Xie, W., Sun, X., Shi, M., Cai, Z., Wang, B., Zhong, M., Li, J., Lu, Z., Gu, N., Zhang, X., Goodman, L., Bolund, L., Wang, J., Yang, H., Kristiansen, K., Dean, M., Li, Y., Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor. Cell 148 (2012), 886–895.
-
(2012)
Cell
, vol.148
, pp. 886-895
-
-
Xu, X.1
Hou, Y.2
Yin, X.3
Bao, L.4
Tang, A.5
Song, L.6
Li, F.7
Tsang, S.8
Wu, K.9
Wu, H.10
He, W.11
Zeng, L.12
Xing, M.13
Wu, R.14
Jiang, H.15
Liu, X.16
Cao, D.17
Guo, G.18
Hu, X.19
Gui, Y.20
Li, Z.21
Xie, W.22
Sun, X.23
Shi, M.24
Cai, Z.25
Wang, B.26
Zhong, M.27
Li, J.28
Lu, Z.29
Gu, N.30
Zhang, X.31
Goodman, L.32
Bolund, L.33
Wang, J.34
Yang, H.35
Kristiansen, K.36
Dean, M.37
Li, Y.38
more..
-
27
-
-
84871461434
-
Genome-wide detection of single-nucleotide and copy-number variations of a single human cell
-
Zong, C., Lu, S., Chapman, A.R., Xie, X.S., Genome-wide detection of single-nucleotide and copy-number variations of a single human cell. Science 338 (2012), 1622–1626.
-
(2012)
Science
, vol.338
, pp. 1622-1626
-
-
Zong, C.1
Lu, S.2
Chapman, A.R.3
Xie, X.S.4
-
28
-
-
84906238686
-
Clonal evolution in breast cancer revealed by single nucleus genome sequencing
-
Wang, Y., Waters, J., Leung, M.L., Unruh, A., Roh, W., Shi, X., Chen, K., Scheet, P., Vattathil, S., Liang, H., Multani, A., Zhang, H., Zhao, R., Michor, F., Meric-Bernstam, F., Navin, N.E., Clonal evolution in breast cancer revealed by single nucleus genome sequencing. Nature 512 (2014), 155–160.
-
(2014)
Nature
, vol.512
, pp. 155-160
-
-
Wang, Y.1
Waters, J.2
Leung, M.L.3
Unruh, A.4
Roh, W.5
Shi, X.6
Chen, K.7
Scheet, P.8
Vattathil, S.9
Liang, H.10
Multani, A.11
Zhang, H.12
Zhao, R.13
Michor, F.14
Meric-Bernstam, F.15
Navin, N.E.16
-
29
-
-
84982161462
-
Punctuated copy number evolution and clonal stasis in triple-negative breast cancer
-
Gao, R., Davis, A., McDonald, T.O., Sei, E., Shi, X., Wang, Y., Tsai, P.C., Casasent, A., Waters, J., Zhang, H., Meric-Bernstam, F., Michor, F., Navin, N.E., Punctuated copy number evolution and clonal stasis in triple-negative breast cancer. Nat. Genet., 2016.
-
(2016)
Nat. Genet.
-
-
Gao, R.1
Davis, A.2
McDonald, T.O.3
Sei, E.4
Shi, X.5
Wang, Y.6
Tsai, P.C.7
Casasent, A.8
Waters, J.9
Zhang, H.10
Meric-Bernstam, F.11
Michor, F.12
Navin, N.E.13
-
30
-
-
84929661801
-
Advances and applications of single-cell sequencing technologies
-
Wang, Y., Navin, N.E., Advances and applications of single-cell sequencing technologies. Mol. Cell 58 (2015), 598–609.
-
(2015)
Mol. Cell
, vol.58
, pp. 598-609
-
-
Wang, Y.1
Navin, N.E.2
-
31
-
-
85027920141
-
Cancer genomics: one cell at a time
-
Navin, N.E., Cancer genomics: one cell at a time. Genome Biol., 15, 2014, 452.
-
(2014)
Genome Biol.
, vol.15
, pp. 452
-
-
Navin, N.E.1
-
32
-
-
84884963475
-
TrAp: a tree approach for fingerprinting subclonal tumor composition
-
Strino, F., Parisi, F., Micsinai, M., Kluger, Y., TrAp: a tree approach for fingerprinting subclonal tumor composition. Nucleic Acids Res., 41, 2013, e165.
-
(2013)
Nucleic Acids Res.
, vol.41
-
-
Strino, F.1
Parisi, F.2
Micsinai, M.3
Kluger, Y.4
-
33
-
-
84902455399
-
A combinatorial approach for analyzing intra-tumor heterogeneity from high-throughput sequencing data
-
Hajirasouliha, I., Mahmoody, A., Raphael, B.J., A combinatorial approach for analyzing intra-tumor heterogeneity from high-throughput sequencing data. Bioinformatics 30 (2014), i78–i86.
-
(2014)
Bioinformatics
, vol.30
, pp. i78-i86
-
-
Hajirasouliha, I.1
Mahmoody, A.2
Raphael, B.J.3
-
34
-
-
84931036281
-
Reconstruction of clonal trees and tumor composition from multi-sample sequencing data
-
El-Kebir, M., Oesper, L., Acheson-Field, H., Raphael, B.J., Reconstruction of clonal trees and tumor composition from multi-sample sequencing data. Bioinformatics 31 (2015), i62–i70.
-
(2015)
Bioinformatics
, vol.31
, pp. i62-i70
-
-
El-Kebir, M.1
Oesper, L.2
Acheson-Field, H.3
Raphael, B.J.4
-
35
-
-
84964314164
-
SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization
-
Qiao, Y., Quinlan, A.R., Jazaeri, A.A., Verhaak, R.G., Wheeler, D.A., Marth, G.T., SubcloneSeeker: a computational framework for reconstructing tumor clone structure for cancer variant interpretation and prioritization. Genome Biol., 15, 2014, 443.
-
(2014)
Genome Biol.
, vol.15
, pp. 443
-
-
Qiao, Y.1
Quinlan, A.R.2
Jazaeri, A.A.3
Verhaak, R.G.4
Wheeler, D.A.5
Marth, G.T.6
-
36
-
-
84935825808
-
PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors
-
Deshwar, A.G., Vembu, S., Yung, C.K., Jang, G.H., Stein, L., Morris, Q., PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors. Genome Biol., 16, 2015, 35.
-
(2015)
Genome Biol.
, vol.16
, pp. 35
-
-
Deshwar, A.G.1
Vembu, S.2
Yung, C.K.3
Jang, G.H.4
Stein, L.5
Morris, Q.6
-
37
-
-
84893164721
-
Inferring clonal evolution of tumors from single nucleotide somatic mutations
-
Jiao, W., Vembu, S., Deshwar, A.G., Stein, L., Morris, Q., Inferring clonal evolution of tumors from single nucleotide somatic mutations. BMC Bioinf., 15, 2014, 35.
-
(2014)
BMC Bioinf.
, vol.15
, pp. 35
-
-
Jiao, W.1
Vembu, S.2
Deshwar, A.G.3
Stein, L.4
Morris, Q.5
-
38
-
-
84931025210
-
Clonality inference in multiple tumor samples using phylogeny
-
Malikic, S., McPherson, A.W., Donmez, N., Sahinalp, C.S., Clonality inference in multiple tumor samples using phylogeny. Bioinformatics 31 (2015), 1349–1356.
-
(2015)
Bioinformatics
, vol.31
, pp. 1349-1356
-
-
Malikic, S.1
McPherson, A.W.2
Donmez, N.3
Sahinalp, C.S.4
-
39
-
-
84937046175
-
Fast and scalable inference of multi-sample cancer lineages
-
Popic, V., Salari, R., Hajirasouliha, I., Kashef-Haghighi, D., West, R.B., Batzoglou, S., Fast and scalable inference of multi-sample cancer lineages. Genome Biol., 16, 2015, 91.
-
(2015)
Genome Biol.
, vol.16
, pp. 91
-
-
Popic, V.1
Salari, R.2
Hajirasouliha, I.3
Kashef-Haghighi, D.4
West, R.B.5
Batzoglou, S.6
-
40
-
-
84935892963
-
BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies
-
Yuan, K., Sakoparnig, T., Markowetz, F., Beerenwinkel, N., BitPhylogeny: a probabilistic framework for reconstructing intra-tumor phylogenies. Genome Biol., 16, 2015, 36.
-
(2015)
Genome Biol.
, vol.16
, pp. 36
-
-
Yuan, K.1
Sakoparnig, T.2
Markowetz, F.3
Beerenwinkel, N.4
-
41
-
-
84901318643
-
Phylogenetic quantification of intra-tumour heterogeneity
-
Schwarz, R.F., Trinh, A., Sipos, B., Brenton, J.D., Goldman, N., Markowetz, F., Phylogenetic quantification of intra-tumour heterogeneity. PLoS Comput. Biol., 10, 2014, e1003535.
-
(2014)
PLoS Comput. Biol.
, vol.10
-
-
Schwarz, R.F.1
Trinh, A.2
Sipos, B.3
Brenton, J.D.4
Goldman, N.5
Markowetz, F.6
-
42
-
-
77954772548
-
Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis
-
Letouze, E., Allory, Y., Bollet, M.A., Radvanyi, F., Guyon, F., Analysis of the copy number profiles of several tumor samples from the same patient reveals the successive steps in tumorigenesis. Genome Biol., 11, 2010, R76.
-
(2010)
Genome Biol.
, vol.11
, pp. R76
-
-
Letouze, E.1
Allory, Y.2
Bollet, M.A.3
Radvanyi, F.4
Guyon, F.5
-
43
-
-
84965070761
-
Tree inference for single-cell data
-
Jahn, K., Kuipers, J., Beerenwinkel, N., Tree inference for single-cell data. Genome Biol., 17, 2016, 86.
-
(2016)
Genome Biol.
, vol.17
, pp. 86
-
-
Jahn, K.1
Kuipers, J.2
Beerenwinkel, N.3
-
44
-
-
84968662246
-
Clonal genotype and population structure inference from single-cell tumor sequencing
-
Roth, A., McPherson, A., Laks, E., Biele, J., Yap, D., Wan, A., Smith, M.A., Nielsen, C.B., McAlpine, J.N., Aparicio, S., Bouchard-Cote, A., Shah, S.P., Clonal genotype and population structure inference from single-cell tumor sequencing. Nat. Methods, 2016.
-
(2016)
Nat. Methods
-
-
Roth, A.1
McPherson, A.2
Laks, E.3
Biele, J.4
Yap, D.5
Wan, A.6
Smith, M.A.7
Nielsen, C.B.8
McAlpine, J.N.9
Aparicio, S.10
Bouchard-Cote, A.11
Shah, S.P.12
-
45
-
-
84962900955
-
OncoNEM: inferring tumor evolution from single-cell sequencing data
-
Ross, E.M., Markowetz, F., OncoNEM: inferring tumor evolution from single-cell sequencing data. Genome Biol., 17, 2016, 69.
-
(2016)
Genome Biol.
, vol.17
, pp. 69
-
-
Ross, E.M.1
Markowetz, F.2
-
46
-
-
0014494672
-
The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations
-
Kimura, M., The number of heterozygous nucleotide sites maintained in a finite population due to steady flux of mutations. Genetics 61 (1969), 893–903.
-
(1969)
Genetics
, vol.61
, pp. 893-903
-
-
Kimura, M.1
-
47
-
-
84859125350
-
Intratumor heterogeneity: seeing the wood for the trees
-
(127ps110-127ps110)
-
Yap, T.A., Gerlinger, M., Futreal, P.A., Pusztai, L., Swanton, C., Intratumor heterogeneity: seeing the wood for the trees. Sci. Transl. Med., 4, 2012 (127ps110-127ps110).
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Yap, T.A.1
Gerlinger, M.2
Futreal, P.A.3
Pusztai, L.4
Swanton, C.5
-
48
-
-
0025312728
-
A genetic model for colorectal tumorigenesis
-
Fearon, E., Vogelstein, B., A genetic model for colorectal tumorigenesis. Cell, 1990.
-
(1990)
Cell
-
-
Fearon, E.1
Vogelstein, B.2
-
49
-
-
0001872496
-
Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas
-
Linder, D., Gartler, S.M., Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas. Science 150 (1965), 67–69.
-
(1965)
Science
, vol.150
, pp. 67-69
-
-
Linder, D.1
Gartler, S.M.2
-
50
-
-
0016184570
-
The origin and development of human tumors studied with cell markers
-
Fialkow, P.J., The origin and development of human tumors studied with cell markers. N. Engl. J. Med. 291 (1974), 26–35.
-
(1974)
N. Engl. J. Med.
, vol.291
, pp. 26-35
-
-
Fialkow, P.J.1
-
51
-
-
84906644626
-
Human genetic markers as tracers of tumour histogenesis
-
Fialkow, P.J., Human genetic markers as tracers of tumour histogenesis. J. Clin. Pathol. Suppl. (R. Coll. Pathol.) 7 (1974), 11–15.
-
(1974)
J. Clin. Pathol. Suppl. (R. Coll. Pathol.)
, vol.7
, pp. 11-15
-
-
Fialkow, P.J.1
-
52
-
-
0026496738
-
Clonal analysis of human breast cancer by means of the polymerase chain reaction
-
Noguchi, S., Motomura, K., Inaji, H., Imaoka, S., Koyama, H., Clonal analysis of human breast cancer by means of the polymerase chain reaction. Cancer Res. 52 (1992), 6594–6597.
-
(1992)
Cancer Res.
, vol.52
, pp. 6594-6597
-
-
Noguchi, S.1
Motomura, K.2
Inaji, H.3
Imaoka, S.4
Koyama, H.5
-
53
-
-
0028018115
-
Clonal analysis of human gynecologic cancers by means of the polymerase chain reaction
-
Sawada, M., Azuma, C., Hashimoto, K., Noguchi, S., Ozaki, M., Saji, F., Tanizawa, O., Clonal analysis of human gynecologic cancers by means of the polymerase chain reaction. Int. J. Cancer 58 (1994), 492–496.
-
(1994)
Int. J. Cancer
, vol.58
, pp. 492-496
-
-
Sawada, M.1
Azuma, C.2
Hashimoto, K.3
Noguchi, S.4
Ozaki, M.5
Saji, F.6
Tanizawa, O.7
-
54
-
-
84863229772
-
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm
-
Hou, Y., Song, L., Zhu, P., Zhang, B., Tao, Y., Xu, X., Li, F., Wu, K., Liang, J., Shao, D., Wu, H., Ye, X., Ye, C., Wu, R., Jian, M., Chen, Y., Xie, W., Zhang, R., Chen, L., Liu, X., Yao, X., Zheng, H., Yu, C., Li, Q., Gong, Z., Mao, M., Yang, X., Yang, L., Li, J., Wang, W., Lu, Z., Gu, N., Laurie, G., Bolund, L., Kristiansen, K., Wang, J., Yang, H., Li, Y., Zhang, X., Wang, J., Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell 148 (2012), 873–885.
-
(2012)
Cell
, vol.148
, pp. 873-885
-
-
Hou, Y.1
Song, L.2
Zhu, P.3
Zhang, B.4
Tao, Y.5
Xu, X.6
Li, F.7
Wu, K.8
Liang, J.9
Shao, D.10
Wu, H.11
Ye, X.12
Ye, C.13
Wu, R.14
Jian, M.15
Chen, Y.16
Xie, W.17
Zhang, R.18
Chen, L.19
Liu, X.20
Yao, X.21
Zheng, H.22
Yu, C.23
Li, Q.24
Gong, Z.25
Mao, M.26
Yang, X.27
Yang, L.28
Li, J.29
Wang, W.30
Lu, Z.31
Gu, N.32
Laurie, G.33
Bolund, L.34
Kristiansen, K.35
Wang, J.36
Yang, H.37
Li, Y.38
Zhang, X.39
Wang, J.40
more..
-
55
-
-
84887255230
-
Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer
-
Li, Y., Xu, X., Song, L., Hou, Y., Li, Z., Tsang, S., Li, F., Im, K.M., Wu, K., Wu, H., Ye, X., Li, G., Wang, L., Zhang, B., Liang, J., Xie, W., Wu, R., Jiang, H., Liu, X., Yu, C., Zheng, H., Jian, M., Nie, L., Wan, L., Shi, M., Sun, X., Tang, A., Guo, G., Gui, Y., Cai, Z., Li, J., Wang, W., Lu, Z., Zhang, X., Bolund, L., Kristiansen, K., Wang, J., Yang, H., Dean, M., Wang, J., Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer. GigaScience, 1, 2012, 12.
-
(2012)
GigaScience
, vol.1
, pp. 12
-
-
Li, Y.1
Xu, X.2
Song, L.3
Hou, Y.4
Li, Z.5
Tsang, S.6
Li, F.7
Im, K.M.8
Wu, K.9
Wu, H.10
Ye, X.11
Li, G.12
Wang, L.13
Zhang, B.14
Liang, J.15
Xie, W.16
Wu, R.17
Jiang, H.18
Liu, X.19
Yu, C.20
Zheng, H.21
Jian, M.22
Nie, L.23
Wan, L.24
Shi, M.25
Sun, X.26
Tang, A.27
Guo, G.28
Gui, Y.29
Cai, Z.30
Li, J.31
Wang, W.32
Lu, Z.33
Zhang, X.34
Bolund, L.35
Kristiansen, K.36
Wang, J.37
Yang, H.38
Dean, M.39
Wang, J.40
more..
-
56
-
-
84901835055
-
Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing
-
Yu, C., Yu, J., Yao, X., Wu, W.K., Lu, Y., Tang, S., Li, X., Bao, L., Li, X., Hou, Y., Wu, R., Jian, M., Chen, R., Zhang, F., Xu, L., Fan, F., He, J., Liang, Q., Wang, H., Hu, X., He, M., Zhang, X., Zheng, H., Li, Q., Wu, H., Chen, Y., Yang, X., Zhu, S., Xu, X., Yang, H., Wang, J., Zhang, X., Sung, J.J., Li, Y., Wang, J., Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing. Cell Res. 24 (2014), 701–712.
-
(2014)
Cell Res.
, vol.24
, pp. 701-712
-
-
Yu, C.1
Yu, J.2
Yao, X.3
Wu, W.K.4
Lu, Y.5
Tang, S.6
Li, X.7
Bao, L.8
Li, X.9
Hou, Y.10
Wu, R.11
Jian, M.12
Chen, R.13
Zhang, F.14
Xu, L.15
Fan, F.16
He, J.17
Liang, Q.18
Wang, H.19
Hu, X.20
He, M.21
Zhang, X.22
Zheng, H.23
Li, Q.24
Wu, H.25
Chen, Y.26
Yang, X.27
Zhu, S.28
Xu, X.29
Yang, H.30
Wang, J.31
Zhang, X.32
Sung, J.J.33
Li, Y.34
Wang, J.35
more..
-
57
-
-
84919372228
-
Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics
-
Gawad, C., Koh, W., Quake, S.R., Dissecting the clonal origins of childhood acute lymphoblastic leukemia by single-cell genomics. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 17947–17952.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 17947-17952
-
-
Gawad, C.1
Koh, W.2
Quake, S.R.3
-
58
-
-
84944468397
-
Subclonal genomic architectures of primary and metastatic colorectal cancer based on intratumoral genetic heterogeneity
-
Kim, T.M., Jung, S.H., An, C.H., Lee, S.H., Baek, I.P., Kim, M.S., Park, S.W., Rhee, J.K., Lee, S.H., Chung, Y.J., Subclonal genomic architectures of primary and metastatic colorectal cancer based on intratumoral genetic heterogeneity. Clin. Cancer Res. 21 (2015), 4461–4472.
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 4461-4472
-
-
Kim, T.M.1
Jung, S.H.2
An, C.H.3
Lee, S.H.4
Baek, I.P.5
Kim, M.S.6
Park, S.W.7
Rhee, J.K.8
Lee, S.H.9
Chung, Y.J.10
-
59
-
-
84907808265
-
Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing
-
Zhang, J., Fujimoto, J., Zhang, J., Wedge, D.C., Song, X., Zhang, J., Seth, S., Chow, C.-W., Cao, Y., Gumbs, C., Gold, K.A., Kalhor, N., Little, L., Mahadeshwar, H., Moran, C., Protopopov, A., Sun, H., Tang, J., Wu, X., Ye, Y., William, W.N., Lee, J.J., Heymach, J.V., Hong, W.K., Swisher, S., Wistuba, I.I., Futreal, P.A., Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing. Science 346 (2014), 256–259.
-
(2014)
Science
, vol.346
, pp. 256-259
-
-
Zhang, J.1
Fujimoto, J.2
Zhang, J.3
Wedge, D.C.4
Song, X.5
Zhang, J.6
Seth, S.7
Chow, C.-W.8
Cao, Y.9
Gumbs, C.10
Gold, K.A.11
Kalhor, N.12
Little, L.13
Mahadeshwar, H.14
Moran, C.15
Protopopov, A.16
Sun, H.17
Tang, J.18
Wu, X.19
Ye, Y.20
William, W.N.21
Lee, J.J.22
Heymach, J.V.23
Hong, W.K.24
Swisher, S.25
Wistuba, I.I.26
Futreal, P.A.27
more..
-
60
-
-
84907855592
-
Spatial and temporal diversity in genomic instability processes defines lung cancer evolution
-
de Bruin, E.C., McGranahan, N., Mitter, R., Salm, M., Wedge, D.C., Yates, L., Jamal-Hanjani, M., Shafi, S., Murugaesu, N., Rowan, A.J., Gronroos, E., Muhammad, M.A., Horswell, S., Gerlinger, M., Varela, I., Jones, D., Marshall, J., Voet, T., Van Loo, P., Rassl, D.M., Rintoul, R.C., Janes, S.M., Lee, S.-M., Forster, M., Ahmad, T., Lawrence, D., Falzon, M., Capitanio, A., Harkins, T.T., Lee, C.C., Tom, W., Teefe, E., Chen, S.-C., Begum, S., Rabinowitz, A., Phillimore, B., Spencer-Dene, B., Stamp, G., Szallasi, Z., Matthews, N., Stewart, A., Campbell, P., Swanton, C., Spatial and temporal diversity in genomic instability processes defines lung cancer evolution. Science 346 (2014), 251–256.
-
(2014)
Science
, vol.346
, pp. 251-256
-
-
de Bruin, E.C.1
McGranahan, N.2
Mitter, R.3
Salm, M.4
Wedge, D.C.5
Yates, L.6
Jamal-Hanjani, M.7
Shafi, S.8
Murugaesu, N.9
Rowan, A.J.10
Gronroos, E.11
Muhammad, M.A.12
Horswell, S.13
Gerlinger, M.14
Varela, I.15
Jones, D.16
Marshall, J.17
Voet, T.18
Van Loo, P.19
Rassl, D.M.20
Rintoul, R.C.21
Janes, S.M.22
Lee, S.-M.23
Forster, M.24
Ahmad, T.25
Lawrence, D.26
Falzon, M.27
Capitanio, A.28
Harkins, T.T.29
Lee, C.C.30
Tom, W.31
Teefe, E.32
Chen, S.-C.33
Begum, S.34
Rabinowitz, A.35
Phillimore, B.36
Spencer-Dene, B.37
Stamp, G.38
Szallasi, Z.39
Matthews, N.40
Stewart, A.41
Campbell, P.42
Swanton, C.43
more..
-
61
-
-
84936890500
-
Subclonal diversification of primary breast cancer revealed by multiregion sequencing
-
Yates, L.R., Gerstung, M., Knappskog, S., Desmedt, C., Gundem, G., Van Loo, P., Aas, T., Alexandrov, L.B., Larsimont, D., Davies, H., Li, Y., Ju, Y.S., Ramakrishna, M., Haugland, H.K., Lilleng, P.K., Nik-Zainal, S., McLaren, S., Butler, A., Martin, S., Glodzik, D., Menzies, A., Raine, K., Hinton, J., Jones, D., Mudie, L.J., Jiang, B., Vincent, D., Greene-Colozzi, A., Adnet, P.-Y., Fatima, A., Maetens, M., Ignatiadis, M., Stratton, M.R., Sotiriou, C., Richardson, A.L., Lønning, P.E., Wedge, D.C., Campbell, P.J., Subclonal diversification of primary breast cancer revealed by multiregion sequencing. Nat. Med. 21 (2015), 751–759.
-
(2015)
Nat. Med.
, vol.21
, pp. 751-759
-
-
Yates, L.R.1
Gerstung, M.2
Knappskog, S.3
Desmedt, C.4
Gundem, G.5
Van Loo, P.6
Aas, T.7
Alexandrov, L.B.8
Larsimont, D.9
Davies, H.10
Li, Y.11
Ju, Y.S.12
Ramakrishna, M.13
Haugland, H.K.14
Lilleng, P.K.15
Nik-Zainal, S.16
McLaren, S.17
Butler, A.18
Martin, S.19
Glodzik, D.20
Menzies, A.21
Raine, K.22
Hinton, J.23
Jones, D.24
Mudie, L.J.25
Jiang, B.26
Vincent, D.27
Greene-Colozzi, A.28
Adnet, P.-Y.29
Fatima, A.30
Maetens, M.31
Ignatiadis, M.32
Stratton, M.R.33
Sotiriou, C.34
Richardson, A.L.35
Lønning, P.E.36
Wedge, D.C.37
Campbell, P.J.38
more..
-
62
-
-
84931445758
-
From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity
-
Aubry, M., de Tayrac, M., Etcheverry, A., Clavreul, A., Saikali, S., Menei, P., Mosser, J., From the core to beyond the margin: a genomic picture of glioblastoma intratumor heterogeneity. Oncotarget 6 (2015), 12094–12109.
-
(2015)
Oncotarget
, vol.6
, pp. 12094-12109
-
-
Aubry, M.1
de Tayrac, M.2
Etcheverry, A.3
Clavreul, A.4
Saikali, S.5
Menei, P.6
Mosser, J.7
-
63
-
-
85017046717
-
Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
-
Hoffman, L.M., Dewire, M., Ryall, S., Buczkowicz, P., Leach, J., Miles, L., Ramani, A., Brudno, M., Kumar, S.S., Drissi, R., Dexheimer, P., Salloum, R., Chow, L., Hummel, T., Stevenson, C., Lu, Q.R., Jones, B., Witte, D., Aronow, B., Hawkins, C.E., Fouladi, M., Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics. Acta Neuropathol. Commun., 4, 2016, 1.
-
(2016)
Acta Neuropathol. Commun.
, vol.4
, pp. 1
-
-
Hoffman, L.M.1
Dewire, M.2
Ryall, S.3
Buczkowicz, P.4
Leach, J.5
Miles, L.6
Ramani, A.7
Brudno, M.8
Kumar, S.S.9
Drissi, R.10
Dexheimer, P.11
Salloum, R.12
Chow, L.13
Hummel, T.14
Stevenson, C.15
Lu, Q.R.16
Jones, B.17
Witte, D.18
Aronow, B.19
Hawkins, C.E.20
Fouladi, M.21
more..
-
64
-
-
84933277410
-
Spatial genomic heterogeneity within localized, multifocal prostate cancer
-
Boutros, P.C., Fraser, M., Harding, N.J., de Borja, R., Trudel, D., Lalonde, E., Meng, A., Hennings-Yeomans, P.H., McPherson, A., Sabelnykova, V.Y., Zia, A., Fox, N.S., Livingstone, J., Shiah, Y.-J., Wang, J., Beck, T.A., Have, C.L., Chong, T., Sam, M., Johns, J., Timms, L., Buchner, N., Wong, A., Watson, J.D., Simmons, T.T., P'ng, C., Zafarana, G., Nguyen, F., Luo, X., Chu, K.C., Prokopec, S.D., Sykes, J., Dal Pra, A., Berlin, A., Brown, A., Chan-Seng-Yue, M.A., Yousif, F., Denroche, R.E., Chong, L.C., Chen, G.M., Jung, E., Fung, C., Starmans, M.H.W., Chen, H., Govind, S.K., Hawley, J., D'Costa, A., Pintilie, M., Waggott, D., Hach, F., Lambin, P., Muthuswamy, L.B., Cooper, C., Eeles, R., Neal, D., Tetu, B., Sahinalp, C., Stein, L.D., Fleshner, N., Shah, S.P., Collins, C.C., Hudson, T.J., McPherson, J.D., van der Kwast, T., Bristow, R.G., Spatial genomic heterogeneity within localized, multifocal prostate cancer. Nat. Genet. 47 (2015), 1–14.
-
(2015)
Nat. Genet.
, vol.47
, pp. 1-14
-
-
Boutros, P.C.1
Fraser, M.2
Harding, N.J.3
de Borja, R.4
Trudel, D.5
Lalonde, E.6
Meng, A.7
Hennings-Yeomans, P.H.8
McPherson, A.9
Sabelnykova, V.Y.10
Zia, A.11
Fox, N.S.12
Livingstone, J.13
Shiah, Y.-J.14
Wang, J.15
Beck, T.A.16
Have, C.L.17
Chong, T.18
Sam, M.19
Johns, J.20
Timms, L.21
Buchner, N.22
Wong, A.23
Watson, J.D.24
Simmons, T.T.25
P'ng, C.26
Zafarana, G.27
Nguyen, F.28
Luo, X.29
Chu, K.C.30
Prokopec, S.D.31
Sykes, J.32
Dal Pra, A.33
Berlin, A.34
Brown, A.35
Chan-Seng-Yue, M.A.36
Yousif, F.37
Denroche, R.E.38
Chong, L.C.39
Chen, G.M.40
Jung, E.41
Fung, C.42
Starmans, M.H.W.43
Chen, H.44
Govind, S.K.45
Hawley, J.46
D'Costa, A.47
Pintilie, M.48
Waggott, D.49
Hach, F.50
Lambin, P.51
Muthuswamy, L.B.52
Cooper, C.53
Eeles, R.54
Neal, D.55
Tetu, B.56
Sahinalp, C.57
Stein, L.D.58
Fleshner, N.59
Shah, S.P.60
Collins, C.C.61
Hudson, T.J.62
McPherson, J.D.63
van der Kwast, T.64
Bristow, R.G.65
more..
-
65
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida, S., Jones, S., Bozic, I., Antal, T., Leary, R., Fu, B., Kamiyama, M., Hruban, R.H., Eshleman, J.R., Nowak, M.A., Velculescu, V.E., Kinzler, K.W., Vogelstein, B., Iacobuzio-Donahue, C.A., Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 467 (2010), 1114–1117.
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
Antal, T.4
Leary, R.5
Fu, B.6
Kamiyama, M.7
Hruban, R.H.8
Eshleman, J.R.9
Nowak, M.A.10
Velculescu, V.E.11
Kinzler, K.W.12
Vogelstein, B.13
Iacobuzio-Donahue, C.A.14
-
66
-
-
51349126920
-
Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing
-
Campbell, P.J., Pleasance, E.D., Stephens, P.J., Dicks, E., Rance, R., Goodhead, I., Follows, G.A., Green, A.R., Futreal, P.A., Stratton, M.R., Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing. Proc. Natl. Acad. Sci. U. S. A. 105 (2008), 13081–13086.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 13081-13086
-
-
Campbell, P.J.1
Pleasance, E.D.2
Stephens, P.J.3
Dicks, E.4
Rance, R.5
Goodhead, I.6
Follows, G.A.7
Green, A.R.8
Futreal, P.A.9
Stratton, M.R.10
-
67
-
-
84862776906
-
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing
-
Ding, L., Ley, T.J., Larson, D.E., Miller, C.A., Koboldt, D.C., Welch, J.S., Ritchey, J.K., Young, M.A., Lamprecht, T., McLellan, M.D., McMichael, J.F., Wallis, J.W., Lu, C., Shen, D., Harris, C.C., Dooling, D.J., Fulton, R.S., Fulton, L.L., Chen, K., Schmidt, H., Kalicki-Veizer, J., Magrini, V.J., Cook, L., McGrath, S.D., Vickery, T.L., Wendl, M.C., Heath, S., Watson, M.A., Link, D.C., Tomasson, M.H., Shannon, W.D., Payton, J.E., Kulkarni, S., Westervelt, P., Walter, M.J., Graubert, T.A., Mardis, E.R., Wilson, R.K., DiPersio, J.F., Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature 481 (2012), 506–510.
-
(2012)
Nature
, vol.481
, pp. 506-510
-
-
Ding, L.1
Ley, T.J.2
Larson, D.E.3
Miller, C.A.4
Koboldt, D.C.5
Welch, J.S.6
Ritchey, J.K.7
Young, M.A.8
Lamprecht, T.9
McLellan, M.D.10
McMichael, J.F.11
Wallis, J.W.12
Lu, C.13
Shen, D.14
Harris, C.C.15
Dooling, D.J.16
Fulton, R.S.17
Fulton, L.L.18
Chen, K.19
Schmidt, H.20
Kalicki-Veizer, J.21
Magrini, V.J.22
Cook, L.23
McGrath, S.D.24
Vickery, T.L.25
Wendl, M.C.26
Heath, S.27
Watson, M.A.28
Link, D.C.29
Tomasson, M.H.30
Shannon, W.D.31
Payton, J.E.32
Kulkarni, S.33
Westervelt, P.34
Walter, M.J.35
Graubert, T.A.36
Mardis, E.R.37
Wilson, R.K.38
DiPersio, J.F.39
more..
-
68
-
-
84948428646
-
Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution
-
Ling, S., Hu, Z., Yang, Z., Yang, F., Li, Y., Lin, P., Chen, K., Dong, L., Cao, L., Tao, Y., Hao, L., Chen, Q., Gong, Q., Wu, D., Li, W., Zhao, W., Tian, X., Hao, C., Hungate, E.A., Catenacci, D.V., Hudson, R.R., Li, W.H., Lu, X., Wu, C.I., Extremely high genetic diversity in a single tumor points to prevalence of non-Darwinian cell evolution. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), E6496–E6505.
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, pp. E6496-E6505
-
-
Ling, S.1
Hu, Z.2
Yang, Z.3
Yang, F.4
Li, Y.5
Lin, P.6
Chen, K.7
Dong, L.8
Cao, L.9
Tao, Y.10
Hao, L.11
Chen, Q.12
Gong, Q.13
Wu, D.14
Li, W.15
Zhao, W.16
Tian, X.17
Hao, C.18
Hungate, E.A.19
Catenacci, D.V.20
Hudson, R.R.21
Li, W.H.22
Lu, X.23
Wu, C.I.24
more..
-
69
-
-
84945457918
-
Many private mutations originate from the first few divisions of a human colorectal adenoma
-
Kang, H., Salomon, M.P., Sottoriva, A., Zhao, J., Toy, M., Press, M.F., Curtis, C., Marjoram, P., Siegmund, K., Shibata, D., Many private mutations originate from the first few divisions of a human colorectal adenoma. J. Pathol. 237 (2015), 355–362.
-
(2015)
J. Pathol.
, vol.237
, pp. 355-362
-
-
Kang, H.1
Salomon, M.P.2
Sottoriva, A.3
Zhao, J.4
Toy, M.5
Press, M.F.6
Curtis, C.7
Marjoram, P.8
Siegmund, K.9
Shibata, D.10
-
70
-
-
84923952286
-
A Big Bang model of human colorectal tumor growth
-
Sottoriva, A., Kang, H., Ma, Z., Graham, T.A., Salomon, M.P., Zhao, J., Marjoram, P., Siegmund, K., Press, M.F., Shibata, D., Curtis, C., A Big Bang model of human colorectal tumor growth. Nat. Genet. 47 (2015), 209–216.
-
(2015)
Nat. Genet.
, vol.47
, pp. 209-216
-
-
Sottoriva, A.1
Kang, H.2
Ma, Z.3
Graham, T.A.4
Salomon, M.P.5
Zhao, J.6
Marjoram, P.7
Siegmund, K.8
Press, M.F.9
Shibata, D.10
Curtis, C.11
-
71
-
-
84885092663
-
Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling
-
Bashashati, A., Ha, G., Tone, A., Ding, J., Prentice, L.M., Roth, A., Rosner, J., Shumansky, K., Kalloger, S., Senz, J., Yang, W., McConechy, M., Melnyk, N., Anglesio, M., Luk, M.T.Y., Tse, K., Zeng, T., Moore, R., Zhao, Y., Marra, M.A., Gilks, B., Yip, S., Huntsman, D.G., McAlpine, J.N., Shah, S.P., Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling. J. Pathol. 231 (2013), 21–34.
-
(2013)
J. Pathol.
, vol.231
, pp. 21-34
-
-
Bashashati, A.1
Ha, G.2
Tone, A.3
Ding, J.4
Prentice, L.M.5
Roth, A.6
Rosner, J.7
Shumansky, K.8
Kalloger, S.9
Senz, J.10
Yang, W.11
McConechy, M.12
Melnyk, N.13
Anglesio, M.14
Luk, M.T.Y.15
Tse, K.16
Zeng, T.17
Moore, R.18
Zhao, Y.19
Marra, M.A.20
Gilks, B.21
Yip, S.22
Huntsman, D.G.23
McAlpine, J.N.24
Shah, S.P.25
more..
-
72
-
-
84982179452
-
Multiregion whole-exome sequencing uncovers the genetic evolution and mutational heterogeneity of early-stage metastatic melanoma
-
Harbst, K., Lauss, M., Cirenajwis, H., Isaksson, K., Rosengren, F., Torngren, T., Kvist, A., Johansson, M.C., Vallon-Christersson, J., Baldetorp, B., Borg, A., Olsson, H., Ingvar, C., Carneiro, A., Jonsson, G., Multiregion whole-exome sequencing uncovers the genetic evolution and mutational heterogeneity of early-stage metastatic melanoma. Cancer Res. 76 (2016), 4765–4774.
-
(2016)
Cancer Res.
, vol.76
, pp. 4765-4774
-
-
Harbst, K.1
Lauss, M.2
Cirenajwis, H.3
Isaksson, K.4
Rosengren, F.5
Torngren, T.6
Kvist, A.7
Johansson, M.C.8
Vallon-Christersson, J.9
Baldetorp, B.10
Borg, A.11
Olsson, H.12
Ingvar, C.13
Carneiro, A.14
Jonsson, G.15
-
73
-
-
84874598318
-
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
-
Sottoriva, A., Spiteri, I., Piccirillo, S.G.M., Touloumis, A., Collins, V.P., Marioni, J.C., Curtis, C., Watts, C., Tavaré, S., Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), 4009–4014.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 4009-4014
-
-
Sottoriva, A.1
Spiteri, I.2
Piccirillo, S.G.M.3
Touloumis, A.4
Collins, V.P.5
Marioni, J.C.6
Curtis, C.7
Watts, C.8
Tavaré, S.9
-
74
-
-
84908032167
-
Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity
-
Marusyk, A., Tabassum, D., Altrock, P., Non-cell-autonomous driving of tumour growth supports sub-clonal heterogeneity. Nature 514 (2014), 54–58.
-
(2014)
Nature
, vol.514
, pp. 54-58
-
-
Marusyk, A.1
Tabassum, D.2
Altrock, P.3
-
75
-
-
84897482887
-
Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers
-
Cleary, A.S., Leonard, T.L., Gestl, S.A., Gunther, E.J., Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers. Nature 508 (2014), 113–117.
-
(2014)
Nature
, vol.508
, pp. 113-117
-
-
Cleary, A.S.1
Leonard, T.L.2
Gestl, S.A.3
Gunther, E.J.4
-
76
-
-
77955911497
-
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
-
Inda, M.-D.-M., Bonavia, R., Mukasa, A., Narita, Y., Sah, D.W.Y., Vandenberg, S., Brennan, C., Johns, T.G., Bachoo, R., Hadwiger, P., Tan, P., Depinho, R.A., Cavenee, W., Furnari, F., Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. Genes Dev. 24 (2010), 1731–1745.
-
(2010)
Genes Dev.
, vol.24
, pp. 1731-1745
-
-
Inda, M.-D.-M.1
Bonavia, R.2
Mukasa, A.3
Narita, Y.4
Sah, D.W.Y.5
Vandenberg, S.6
Brennan, C.7
Johns, T.G.8
Bachoo, R.9
Hadwiger, P.10
Tan, P.11
Depinho, R.A.12
Cavenee, W.13
Furnari, F.14
-
77
-
-
84964240053
-
Biological and therapeutic impact of intratumor heterogeneity in cancer evolution
-
McGranahan, N., Swanton, C., Biological and therapeutic impact of intratumor heterogeneity in cancer evolution. Cancer Cell 27 (2015), 15–26.
-
(2015)
Cancer Cell
, vol.27
, pp. 15-26
-
-
McGranahan, N.1
Swanton, C.2
-
78
-
-
0020991680
-
Rare variant alleles in the light of the neutral theory
-
Kimura, M., Rare variant alleles in the light of the neutral theory. Mol. Biol. Evol. 1 (1983), 84–93.
-
(1983)
Mol. Biol. Evol.
, vol.1
, pp. 84-93
-
-
Kimura, M.1
-
79
-
-
0002690901
-
On the evolution of the base composition of DNA
-
Freese, E., On the evolution of the base composition of DNA. J. Theor. Biol. 3 (1962), 82–101.
-
(1962)
J. Theor. Biol.
, vol.3
, pp. 82-101
-
-
Freese, E.1
-
80
-
-
84959524739
-
Identification of neutral tumor evolution across cancer types
-
Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A., Sottoriva, A., Identification of neutral tumor evolution across cancer types. Nat. Genet., 2016.
-
(2016)
Nat. Genet.
-
-
Williams, M.J.1
Werner, B.2
Barnes, C.P.3
Graham, T.A.4
Sottoriva, A.5
-
81
-
-
0027790582
-
Punctuated equilibrium comes of age
-
Gould, S.J., Eldredge, N., Punctuated equilibrium comes of age. Nature 366 (1993), 223–227.
-
(1993)
Nature
, vol.366
, pp. 223-227
-
-
Gould, S.J.1
Eldredge, N.2
-
82
-
-
0002224909
-
Punctuated equilibria: an alternative to phyletic gradualism
-
Eldredge, N., Gould, S.J., Punctuated equilibria: an alternative to phyletic gradualism. Models Paleobiol., 1972, 82–115.
-
(1972)
Models Paleobiol.
, pp. 82-115
-
-
Eldredge, N.1
Gould, S.J.2
-
83
-
-
33746444714
-
High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors
-
Hicks, J., Muthuswamy, L., Krasnitz, A., Navin, N., Riggs, M., Grubor, V., Esposito, D., Alexander, J., Troge, J., Wigler, M., Maner, S., Lundin, P., Zetterberg, A., High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors. Cold Spring Harb. Symp. Quant. Biol. 70 (2005), 51–63.
-
(2005)
Cold Spring Harb. Symp. Quant. Biol.
, vol.70
, pp. 51-63
-
-
Hicks, J.1
Muthuswamy, L.2
Krasnitz, A.3
Navin, N.4
Riggs, M.5
Grubor, V.6
Esposito, D.7
Alexander, J.8
Troge, J.9
Wigler, M.10
Maner, S.11
Lundin, P.12
Zetterberg, A.13
-
84
-
-
33845291140
-
Novel patterns of genome rearrangement and their association with survival in breast cancer
-
Hicks, J., Krasnitz, A., Lakshmi, B., Navin, N.E., Riggs, M., Leibu, E., Esposito, D., Alexander, J., Troge, J., Grubor, V., Yoon, S., Wigler, M., Ye, K., Borresen-Dale, A.L., Naume, B., Schlicting, E., Norton, L., Hagerstrom, T., Skoog, L., Auer, G., Maner, S., Lundin, P., Zetterberg, A., Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res. 16 (2006), 1465–1479.
-
(2006)
Genome Res.
, vol.16
, pp. 1465-1479
-
-
Hicks, J.1
Krasnitz, A.2
Lakshmi, B.3
Navin, N.E.4
Riggs, M.5
Leibu, E.6
Esposito, D.7
Alexander, J.8
Troge, J.9
Grubor, V.10
Yoon, S.11
Wigler, M.12
Ye, K.13
Borresen-Dale, A.L.14
Naume, B.15
Schlicting, E.16
Norton, L.17
Hagerstrom, T.18
Skoog, L.19
Auer, G.20
Maner, S.21
Lundin, P.22
Zetterberg, A.23
more..
-
85
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Stephens, P.J., Greenman, C.D., Fu, B., Yang, F., Bignell, G.R., Mudie, L.J., Pleasance, E.D., Lau, K.W., Beare, D., Stebbings, L.A., McLaren, S., Lin, M.L., McBride, D.J., Varela, I., Nik-Zainal, S., Leroy, C., Jia, M., Menzies, A., Butler, A.P., Teague, J.W., Quail, M.A., Burton, J., Swerdlow, H., Carter, N.P., Morsberger, L.A., Iacobuzio-Donahue, C., Follows, G.A., Green, A.R., Flanagan, A.M., Stratton, M.R., Futreal, P.A., Campbell, P.J., Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 144 (2011), 27–40.
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
Greenman, C.D.2
Fu, B.3
Yang, F.4
Bignell, G.R.5
Mudie, L.J.6
Pleasance, E.D.7
Lau, K.W.8
Beare, D.9
Stebbings, L.A.10
McLaren, S.11
Lin, M.L.12
McBride, D.J.13
Varela, I.14
Nik-Zainal, S.15
Leroy, C.16
Jia, M.17
Menzies, A.18
Butler, A.P.19
Teague, J.W.20
Quail, M.A.21
Burton, J.22
Swerdlow, H.23
Carter, N.P.24
Morsberger, L.A.25
Iacobuzio-Donahue, C.26
Follows, G.A.27
Green, A.R.28
Flanagan, A.M.29
Stratton, M.R.30
Futreal, P.A.31
Campbell, P.J.32
more..
-
86
-
-
84930941966
-
Chromothripsis from DNA damage in micronuclei
-
Zhang, C.-Z., Spektor, A., Cornils, H., Francis, J.M., Jackson, E.K., Liu, S., Meyerson, M., Pellman, D., Chromothripsis from DNA damage in micronuclei. Nature, 2015.
-
(2015)
Nature
-
-
Zhang, C.-Z.1
Spektor, A.2
Cornils, H.3
Francis, J.M.4
Jackson, E.K.5
Liu, S.6
Meyerson, M.7
Pellman, D.8
-
87
-
-
80054698731
-
Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer
-
Kloosterman, W.P., Hoogstraat, M., Paling, O., Tavakoli-Yaraki, M., Renkens, I., Vermaat, J.S., van Roosmalen, M.J., van Lieshout, S., Nijman, I.J., Roessingh, W., van't Slot, R., van de Belt, J., Guryev, V., Koudijs, M., Voest, E., Cuppen, E., Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer. Genome Biol., 12, 2011, R103.
-
(2011)
Genome Biol.
, vol.12
, pp. R103
-
-
Kloosterman, W.P.1
Hoogstraat, M.2
Paling, O.3
Tavakoli-Yaraki, M.4
Renkens, I.5
Vermaat, J.S.6
van Roosmalen, M.J.7
van Lieshout, S.8
Nijman, I.J.9
Roessingh, W.10
van't Slot, R.11
van de Belt, J.12
Guryev, V.13
Koudijs, M.14
Voest, E.15
Cuppen, E.16
-
88
-
-
79951497419
-
The genomic complexity of primary human prostate cancer
-
Berger, M.F., Lawrence, M.S., Demichelis, F., Drier, Y., Cibulskis, K., Sivachenko, A.Y., Sboner, A., Esgueva, R., Pflueger, D., Sougnez, C., Onofrio, R., Carter, S.L., Park, K., Habegger, L., Ambrogio, L., Fennell, T., Parkin, M., Saksena, G., Voet, D., Ramos, A.H., Pugh, T.J., Wilkinson, J., Fisher, S., Winckler, W., Mahan, S., Ardlie, K., Baldwin, J., Simons, J.W., Kitabayashi, N., MacDonald, T.Y., Kantoff, P.W., Chin, L., Gabriel, S.B., Gerstein, M.B., Golub, T.R., Meyerson, M., Tewari, A., Lander, E.S., Getz, G., Rubin, M.A., Garraway, L.A., The genomic complexity of primary human prostate cancer. Nature 470 (2011), 214–220.
-
(2011)
Nature
, vol.470
, pp. 214-220
-
-
Berger, M.F.1
Lawrence, M.S.2
Demichelis, F.3
Drier, Y.4
Cibulskis, K.5
Sivachenko, A.Y.6
Sboner, A.7
Esgueva, R.8
Pflueger, D.9
Sougnez, C.10
Onofrio, R.11
Carter, S.L.12
Park, K.13
Habegger, L.14
Ambrogio, L.15
Fennell, T.16
Parkin, M.17
Saksena, G.18
Voet, D.19
Ramos, A.H.20
Pugh, T.J.21
Wilkinson, J.22
Fisher, S.23
Winckler, W.24
Mahan, S.25
Ardlie, K.26
Baldwin, J.27
Simons, J.W.28
Kitabayashi, N.29
MacDonald, T.Y.30
Kantoff, P.W.31
Chin, L.32
Gabriel, S.B.33
Gerstein, M.B.34
Golub, T.R.35
Meyerson, M.36
Tewari, A.37
Lander, E.S.38
Getz, G.39
Rubin, M.A.40
Garraway, L.A.41
more..
-
89
-
-
84930638395
-
Whole-genome characterization of chemoresistant ovarian cancer
-
Patch, A.M., Christie, E.L., Etemadmoghadam, D., Garsed, D.W., George, J., Fereday, S., Nones, K., Cowin, P., Alsop, K., Bailey, P.J., Kassahn, K.S., Newell, F., Quinn, M.C., Kazakoff, S., Quek, K., Wilhelm-Benartzi, C., Curry, E., Leong, H.S., G. Australian Ovarian Cancer Study, Hamilton, A., Mileshkin, L., Au-Yeung, G., Kennedy, C., Hung, J., Chiew, Y.E., Harnett, P., Friedlander, M., Quinn, M., Pyman, J., Cordner, S., O'Brien, P., Leditschke, J., Young, G., Strachan, K., Waring, P., Azar, W., Mitchell, C., Traficante, N., Hendley, J., Thorne, H., Shackleton, M., Miller, D.K., Arnau, G.M., Tothill, R.W., Holloway, T.P., Semple, T., Harliwong, I., Nourse, C., Nourbakhsh, E., Manning, S., Idrisoglu, S., Bruxner, T.J., Christ, A.N., Poudel, B., Holmes, O., Anderson, M., Leonard, C., Lonie, A., Hall, N., Wood, S., Taylor, D.F., Xu, Q., Fink, J.L., Waddell, N., Drapkin, R., Stronach, E., Gabra, H., Brown, R., Jewell, A., Nagaraj, S.H., Markham, E., Wilson, P.J., Ellul, J., McNally, O., Doyle, M.A., Vedururu, R., Stewart, C., Lengyel, E., Pearson, J.V., Waddell, N., deFazio, A., Grimmond, S.M., Bowtell, D.D., Whole-genome characterization of chemoresistant ovarian cancer. Nature 521 (2015), 489–494.
-
(2015)
Nature
, vol.521
, pp. 489-494
-
-
Patch, A.M.1
Christie, E.L.2
Etemadmoghadam, D.3
Garsed, D.W.4
George, J.5
Fereday, S.6
Nones, K.7
Cowin, P.8
Alsop, K.9
Bailey, P.J.10
Kassahn, K.S.11
Newell, F.12
Quinn, M.C.13
Kazakoff, S.14
Quek, K.15
Wilhelm-Benartzi, C.16
Curry, E.17
Leong, H.S.18
G. Australian Ovarian Cancer Study19
Hamilton, A.20
Mileshkin, L.21
Au-Yeung, G.22
Kennedy, C.23
Hung, J.24
Chiew, Y.E.25
Harnett, P.26
Friedlander, M.27
Quinn, M.28
Pyman, J.29
Cordner, S.30
O'Brien, P.31
Leditschke, J.32
Young, G.33
Strachan, K.34
Waring, P.35
Azar, W.36
Mitchell, C.37
Traficante, N.38
Hendley, J.39
Thorne, H.40
Shackleton, M.41
Miller, D.K.42
Arnau, G.M.43
Tothill, R.W.44
Holloway, T.P.45
Semple, T.46
Harliwong, I.47
Nourse, C.48
Nourbakhsh, E.49
Manning, S.50
Idrisoglu, S.51
Bruxner, T.J.52
Christ, A.N.53
Poudel, B.54
Holmes, O.55
Anderson, M.56
Leonard, C.57
Lonie, A.58
Hall, N.59
Wood, S.60
Taylor, D.F.61
Xu, Q.62
Fink, J.L.63
Waddell, N.64
Drapkin, R.65
Stronach, E.66
Gabra, H.67
Brown, R.68
Jewell, A.69
Nagaraj, S.H.70
Markham, E.71
Wilson, P.J.72
Ellul, J.73
McNally, O.74
Doyle, M.A.75
Vedururu, R.76
Stewart, C.77
Lengyel, E.78
Pearson, J.V.79
Waddell, N.80
deFazio, A.81
Grimmond, S.M.82
Bowtell, D.D.83
more..
-
90
-
-
84888869068
-
Chromothripsis and Beyond: Rapid Genome Evolution From Complex Chromosomal Rearrangements
-
Zhang, C.Z., Leibowitz, M.L., Pellman, D., Chromothripsis and Beyond: Rapid Genome Evolution From Complex Chromosomal Rearrangements. Genes Dev., 2013, 2513–2530.
-
(2013)
Genes Dev.
, pp. 2513-2530
-
-
Zhang, C.Z.1
Leibowitz, M.L.2
Pellman, D.3
-
91
-
-
84948774105
-
Chromothripsis: a new mechanism for rapid karyotype evolution
-
Leibowitz, M.L., Zhang, C.Z., Pellman, D., Chromothripsis: a new mechanism for rapid karyotype evolution. Annu. Rev. Genet. 49 (2015), 183–211.
-
(2015)
Annu. Rev. Genet.
, vol.49
, pp. 183-211
-
-
Leibowitz, M.L.1
Zhang, C.Z.2
Pellman, D.3
-
92
-
-
74949101897
-
Inferring tumor progression from genomic heterogeneity
-
Navin, N., Krasnitz, A., Rodgers, L., Cook, K., Meth, J., Kendall, J., Riggs, M., Eberling, Y., Troge, J., Grubor, V., Levy, D., Lundin, P., Maner, S., Zetterberg, A., Hicks, J., Wigler, M., Inferring tumor progression from genomic heterogeneity. Genome Res. 20 (2010), 68–80.
-
(2010)
Genome Res.
, vol.20
, pp. 68-80
-
-
Navin, N.1
Krasnitz, A.2
Rodgers, L.3
Cook, K.4
Meth, J.5
Kendall, J.6
Riggs, M.7
Eberling, Y.8
Troge, J.9
Grubor, V.10
Levy, D.11
Lundin, P.12
Maner, S.13
Zetterberg, A.14
Hicks, J.15
Wigler, M.16
-
93
-
-
84875757638
-
Punctuated evolution of prostate cancer genomes
-
Baca, S.C., Prandi, D., Lawrence, M.S., Mosquera, J.M., Romanel, A., Drier, Y., Park, K., Kitabayashi, N., MacDonald, T.Y., Ghandi, M., Van Allen, E., Kryukov, G.V., Sboner, A., Theurillat, J.-P., Soong, T.D., Nickerson, E., Auclair, D., Tewari, A., Beltran, H., Onofrio, R.C., Boysen, G., Guiducci, C., Barbieri, C.E., Cibulskis, K., Sivachenko, A., Carter, S.L., Saksena, G., Voet, D., Ramos, A.H., Winckler, W., Cipicchio, M., Ardlie, K., Kantoff, P.W., Berger, M.F., Gabriel, S.B., Golub, T.R., Meyerson, M., Lander, E.S., Elemento, O., Getz, G., Demichelis, F., Rubin, M.A., Garraway, L.A., Punctuated evolution of prostate cancer genomes. Cell 153 (2013), 666–677.
-
(2013)
Cell
, vol.153
, pp. 666-677
-
-
Baca, S.C.1
Prandi, D.2
Lawrence, M.S.3
Mosquera, J.M.4
Romanel, A.5
Drier, Y.6
Park, K.7
Kitabayashi, N.8
MacDonald, T.Y.9
Ghandi, M.10
Van Allen, E.11
Kryukov, G.V.12
Sboner, A.13
Theurillat, J.-P.14
Soong, T.D.15
Nickerson, E.16
Auclair, D.17
Tewari, A.18
Beltran, H.19
Onofrio, R.C.20
Boysen, G.21
Guiducci, C.22
Barbieri, C.E.23
Cibulskis, K.24
Sivachenko, A.25
Carter, S.L.26
Saksena, G.27
Voet, D.28
Ramos, A.H.29
Winckler, W.30
Cipicchio, M.31
Ardlie, K.32
Kantoff, P.W.33
Berger, M.F.34
Gabriel, S.B.35
Golub, T.R.36
Meyerson, M.37
Lander, E.S.38
Elemento, O.39
Getz, G.40
Demichelis, F.41
Rubin, M.A.42
Garraway, L.A.43
more..
-
94
-
-
79953300544
-
Intratumor heterogeneity in evolutionary models of tumor progression
-
Durrett, R., Foo, J., Leder, K., Mayberry, J., Michor, F., Intratumor heterogeneity in evolutionary models of tumor progression. Genetics 188 (2011), 461–477.
-
(2011)
Genetics
, vol.188
, pp. 461-477
-
-
Durrett, R.1
Foo, J.2
Leder, K.3
Mayberry, J.4
Michor, F.5
-
95
-
-
84879629520
-
Population genetics of neutral mutations in exponentially growing cancer cell populations
-
Durrett, R., Population genetics of neutral mutations in exponentially growing cancer cell populations. Ann. Appl. Probab. 23 (2013), 230–250.
-
(2013)
Ann. Appl. Probab.
, vol.23
, pp. 230-250
-
-
Durrett, R.1
-
96
-
-
84946034176
-
A multitype infinite-allele branching process with applications to cancer evolution
-
McDonald, T.O., Kimmel, M., A multitype infinite-allele branching process with applications to cancer evolution. J. Appl. Probab. 52 (2015), 864–876.
-
(2015)
J. Appl. Probab.
, vol.52
, pp. 864-876
-
-
McDonald, T.O.1
Kimmel, M.2
-
97
-
-
84876527052
-
Modeling neutral evolution using an infinite-allele Markov branching process
-
Wu, X., Kimmel, M., Modeling neutral evolution using an infinite-allele Markov branching process. Int. J. Stoch. Anal., 2013.
-
(2013)
Int. J. Stoch. Anal.
-
-
Wu, X.1
Kimmel, M.2
-
99
-
-
0013120177
-
Branching Processes in Biology
-
Springer New York
-
Kimmel, M., Axelrod, D., Branching Processes in Biology. 2015, Springer, New York.
-
(2015)
-
-
Kimmel, M.1
Axelrod, D.2
-
100
-
-
0025375922
-
Mathematical models of gene amplification with applications to cellular drug resistance and tumorigenicity
-
Kimmel, M., Axelrod, D.E., Mathematical models of gene amplification with applications to cellular drug resistance and tumorigenicity. Genetics 125 (1990), 633–644.
-
(1990)
Genetics
, vol.125
, pp. 633-644
-
-
Kimmel, M.1
Axelrod, D.E.2
-
101
-
-
84873884550
-
Cancer modeling: a personal perspective
-
Durrett, R., Cancer modeling: a personal perspective. Notices AMS 60 (2013), 304–309.
-
(2013)
Notices AMS
, vol.60
, pp. 304-309
-
-
Durrett, R.1
-
102
-
-
79951894811
-
Stochastic dynamics of cancer initiation
-
Foo, J., Leder, K., Michor, F., Stochastic dynamics of cancer initiation. Phys. Biol., 8, 2011, 015002.
-
(2011)
Phys. Biol.
, vol.8
, pp. 015002
-
-
Foo, J.1
Leder, K.2
Michor, F.3
-
103
-
-
79953316881
-
Evolutionary dynamics of intratumor heterogeneity
-
Iwasa, Y., Michor, F., Evolutionary dynamics of intratumor heterogeneity. PLoS One, 6, 2011, e17866.
-
(2011)
PLoS One
, vol.6
-
-
Iwasa, Y.1
Michor, F.2
-
104
-
-
0036792092
-
Metapopulation dynamics and spatial heterogeneity in cancer
-
Gonzalez-Garcia, I., Metapopulation dynamics and spatial heterogeneity in cancer. Proc. Natl. Acad. Sci. 99 (2002), 13085–13089.
-
(2002)
Proc. Natl. Acad. Sci.
, vol.99
, pp. 13085-13089
-
-
Gonzalez-Garcia, I.1
-
105
-
-
77953254299
-
Genetic demixing and evolution in linear stepping stone models
-
Korolev, K.S., Avlund, M., Hallatschek, O., Nelson, D.R., Genetic demixing and evolution in linear stepping stone models. Rev. Mod. Phys. 82 (2010), 1691–1718.
-
(2010)
Rev. Mod. Phys.
, vol.82
, pp. 1691-1718
-
-
Korolev, K.S.1
Avlund, M.2
Hallatschek, O.3
Nelson, D.R.4
-
106
-
-
84941201227
-
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
-
Waclaw, B., Bozic, I., Pittman, M.E., Hruban, R.H., Vogelstein, B., Nowak, M.A., A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity. Nature, 2015.
-
(2015)
Nature
-
-
Waclaw, B.1
Bozic, I.2
Pittman, M.E.3
Hruban, R.H.4
Vogelstein, B.5
Nowak, M.A.6
-
107
-
-
81255175660
-
Interfering waves of adaptation promote spatial mixing
-
Martens, E.A., Hallatschek, O., Interfering waves of adaptation promote spatial mixing. Genetics 189 (2011), 1045–1060.
-
(2011)
Genetics
, vol.189
, pp. 1045-1060
-
-
Martens, E.A.1
Hallatschek, O.2
-
108
-
-
84893830795
-
Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity
-
Almendro, V., Cheng, Y.K., Randles, A., Itzkovitz, S., Marusyk, A., Ametller, E., Gonzalez-Farre, X., Munoz, M., Russnes, H.G., Helland, A., Rye, I.H., Borresen-Dale, A.L., Maruyama, R., van Oudenaarden, A., Dowsett, M., Jones, R.L., Reis-Filho, J., Gascon, P., Gonen, M., Michor, F., Polyak, K., Inference of tumor evolution during chemotherapy by computational modeling and in situ analysis of genetic and phenotypic cellular diversity. Cell Rep. 6 (2014), 514–527.
-
(2014)
Cell Rep.
, vol.6
, pp. 514-527
-
-
Almendro, V.1
Cheng, Y.K.2
Randles, A.3
Itzkovitz, S.4
Marusyk, A.5
Ametller, E.6
Gonzalez-Farre, X.7
Munoz, M.8
Russnes, H.G.9
Helland, A.10
Rye, I.H.11
Borresen-Dale, A.L.12
Maruyama, R.13
van Oudenaarden, A.14
Dowsett, M.15
Jones, R.L.16
Reis-Filho, J.17
Gascon, P.18
Gonen, M.19
Michor, F.20
Polyak, K.21
more..
-
109
-
-
55549113888
-
Simulating brain tumor heterogeneity with a multiscale agent-based model: linking molecular signatures, phenotypes and expansion rate
-
Zhang, L., Strouthos, C.G., Wang, Z., Deisboeck, T.S., Simulating brain tumor heterogeneity with a multiscale agent-based model: linking molecular signatures, phenotypes and expansion rate. Math. Comput. Model. 49 (2009), 307–319.
-
(2009)
Math. Comput. Model.
, vol.49
, pp. 307-319
-
-
Zhang, L.1
Strouthos, C.G.2
Wang, Z.3
Deisboeck, T.S.4
-
110
-
-
36949025507
-
Genetic progression and the waiting time to cancer
-
Beerenwinkel, N., Antal, T., Dingli, D., Traulsen, A., Kinzler, K.W., Velculescu, V.E., Vogelstein, B., Nowak, M.A., Genetic progression and the waiting time to cancer. PLoS Comput. Biol. 3 (2007), 2239–2246.
-
(2007)
PLoS Comput. Biol.
, vol.3
, pp. 2239-2246
-
-
Beerenwinkel, N.1
Antal, T.2
Dingli, D.3
Traulsen, A.4
Kinzler, K.W.5
Velculescu, V.E.6
Vogelstein, B.7
Nowak, M.A.8
-
111
-
-
78249261016
-
Accumulation of driver and passenger mutations during tumor progression
-
Bozic, I., Antal, T., Ohtsuki, H., Carter, H., Kim, D., Chen, S., Karchin, R., Kinzler, K.W., Vogelstein, B., Nowak, M.A., Accumulation of driver and passenger mutations during tumor progression. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 18545–18550.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 18545-18550
-
-
Bozic, I.1
Antal, T.2
Ohtsuki, H.3
Carter, H.4
Kim, D.5
Chen, S.6
Karchin, R.7
Kinzler, K.W.8
Vogelstein, B.9
Nowak, M.A.10
-
112
-
-
84959564974
-
Quantifying clonal and subclonal passenger mutations in cancer evolution
-
Bozic, I., Gerold, J.M., Nowak, M.A., Quantifying clonal and subclonal passenger mutations in cancer evolution. PLoS Comput. Biol. 12 (2016), 1–19.
-
(2016)
PLoS Comput. Biol.
, vol.12
, pp. 1-19
-
-
Bozic, I.1
Gerold, J.M.2
Nowak, M.A.3
-
113
-
-
0141566652
-
New explicit expressions for relative frequencies of single-nucleotide polymorphisms with application to statistical inference on population growth
-
Polanski, A., Kimmel, M., New explicit expressions for relative frequencies of single-nucleotide polymorphisms with application to statistical inference on population growth. Genetics 165 (2003), 427–436.
-
(2003)
Genetics
, vol.165
, pp. 427-436
-
-
Polanski, A.1
Kimmel, M.2
-
114
-
-
84890764282
-
Stochastic hypothesis of transition from inborn neutropenia to AML: interactions of cell population dynamics and population genetics
-
Kimmel, M., Corey, S., Stochastic hypothesis of transition from inborn neutropenia to AML: interactions of cell population dynamics and population genetics. Front. Oncol., 3, 2013, 89.
-
(2013)
Front. Oncol.
, vol.3
, pp. 89
-
-
Kimmel, M.1
Corey, S.2
-
115
-
-
84907055561
-
Resistance to chemotherapy: patient variability and cellular heterogeneity
-
Kessler, D.A., Austin, R.H., Levine, H., Resistance to chemotherapy: patient variability and cellular heterogeneity. Cancer Res. 74 (2014), 4663–4670.
-
(2014)
Cancer Res.
, vol.74
, pp. 4663-4670
-
-
Kessler, D.A.1
Austin, R.H.2
Levine, H.3
-
116
-
-
84959524739
-
Identification of neutral tumor evolution across cancer types
-
Williams, M.J., Werner, B., Barnes, C.P., Graham, T.A., Sottoriva, A., Identification of neutral tumor evolution across cancer types. Nat. Genet. 48 (2016), 238–244.
-
(2016)
Nat. Genet.
, vol.48
, pp. 238-244
-
-
Williams, M.J.1
Werner, B.2
Barnes, C.P.3
Graham, T.A.4
Sottoriva, A.5
-
117
-
-
84880056229
-
Genome evolution during progression to breast cancer
-
Newburger, D.E., Kashef-Haghighi, D., Weng, Z., Salari, R., Sweeney, R.T., Brunner, A.L., Zhu, S.X., Guo, X., Varma, S., Troxell, M.L., West, R.B., Batzoglou, S., Sidow, A., Genome evolution during progression to breast cancer. Genome Res. 23 (2013), 1097–1108.
-
(2013)
Genome Res.
, vol.23
, pp. 1097-1108
-
-
Newburger, D.E.1
Kashef-Haghighi, D.2
Weng, Z.3
Salari, R.4
Sweeney, R.T.5
Brunner, A.L.6
Zhu, S.X.7
Guo, X.8
Varma, S.9
Troxell, M.L.10
West, R.B.11
Batzoglou, S.12
Sidow, A.13
-
118
-
-
4444226253
-
Cancer chromosomes in crisis
-
DePinho, R.A., Polyak, K., Cancer chromosomes in crisis. Nat. Genet. 36 (2004), 932–934.
-
(2004)
Nat. Genet.
, vol.36
, pp. 932-934
-
-
DePinho, R.A.1
Polyak, K.2
-
119
-
-
84857192718
-
Causes and consequences of aneuploidy in cancer
-
Gordon, D.J., Resio, B., Pellman, D., Causes and consequences of aneuploidy in cancer. Nat. Rev. Genet. 13 (2012), 189–203.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 189-203
-
-
Gordon, D.J.1
Resio, B.2
Pellman, D.3
-
120
-
-
33847358842
-
Cell biology: aneuploidy and cancer
-
Pellman, D., Cell biology: aneuploidy and cancer. Nature 446 (2007), 38–39.
-
(2007)
Nature
, vol.446
, pp. 38-39
-
-
Pellman, D.1
-
121
-
-
79957501125
-
Human cancers express mutator phenotypes: origin, consequences and targeting
-
Loeb, L.A., Human cancers express mutator phenotypes: origin, consequences and targeting. Nat. Rev. Cancer 11 (2011), 450–457.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 450-457
-
-
Loeb, L.A.1
-
122
-
-
17044411374
-
Mutator phenotype in cancer: timing and perspectives
-
Bielas, J.H., Loeb, L.A., Mutator phenotype in cancer: timing and perspectives. Environ. Mol. Mutagen. 45 (2005), 206–213.
-
(2005)
Environ. Mol. Mutagen.
, vol.45
, pp. 206-213
-
-
Bielas, J.H.1
Loeb, L.A.2
-
123
-
-
50049087526
-
Many different tumor types have polyclonal tumor origin: evidence and implications
-
Parsons, B.L., Many different tumor types have polyclonal tumor origin: evidence and implications. Mutat. Res. 659 (2008), 232–247.
-
(2008)
Mutat. Res.
, vol.659
, pp. 232-247
-
-
Parsons, B.L.1
-
124
-
-
73349132626
-
Field effect in cancer-an update
-
Chai, H., Brown, R.E., Field effect in cancer-an update. Ann. Clin. Lab. Sci. 39 (2009), 331–337.
-
(2009)
Ann. Clin. Lab. Sci.
, vol.39
, pp. 331-337
-
-
Chai, H.1
Brown, R.E.2
-
125
-
-
84929991442
-
High burden and pervasive positive selection of somatic mutations in normal human skin
-
Martincorena, I., Roshan, A., Gerstung, M., Ellis, P., Van Loo, P., McLaren, S., Wedge, D.C., Fullam, A., Alexandrov, L.B., Tubio, J.M., Stebbings, L., Menzies, A., Widaa, S., Stratton, M.R., Jones, P.H., Campbell, P.J., High burden and pervasive positive selection of somatic mutations in normal human skin. Science 348 (2015), 880–886.
-
(2015)
Science
, vol.348
, pp. 880-886
-
-
Martincorena, I.1
Roshan, A.2
Gerstung, M.3
Ellis, P.4
Van Loo, P.5
McLaren, S.6
Wedge, D.C.7
Fullam, A.8
Alexandrov, L.B.9
Tubio, J.M.10
Stebbings, L.11
Menzies, A.12
Widaa, S.13
Stratton, M.R.14
Jones, P.H.15
Campbell, P.J.16
-
126
-
-
84993661482
-
Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting
-
He, J., Abdel-Wahab, O., Nahas, M.K., Wang, K., Rampal, R.K., Intlekofer, A.M., Patel, J., Krivstov, A., Frampton, G.M., Young, L.E., Zhong, S., Bailey, M., White, J.R., Roels, S., Deffenbaugh, J., Fichtenholtz, A., Brennan, T., Rosenzweig, M., Pelak, K., Knapp, K.M., Brennan, K.W., Donahue, A.L., Young, G., Garcia, L., Beckstrom, S.T., Zhao, M., White, E., Banning, V., Buell, J., Iwanik, K., Ross, J.S., Morosini, D., Younes, A., Hanash, A.M., Paietta, E., Roberts, K., Mullighan, C., Dogan, A., Armstrong, S.A., Mughal, T., Vergilio, J.A., Labrecque, E., Erlich, R., Vietz, C., Yelensky, R., Stephens, P.J., Miller, V.A., van den Brink, M.R., Otto, G.A., Lipson, D., Levine, R.L., Integrated genomic DNA/RNA profiling of hematologic malignancies in the clinical setting. Blood 127 (2016), 3004–3014.
-
(2016)
Blood
, vol.127
, pp. 3004-3014
-
-
He, J.1
Abdel-Wahab, O.2
Nahas, M.K.3
Wang, K.4
Rampal, R.K.5
Intlekofer, A.M.6
Patel, J.7
Krivstov, A.8
Frampton, G.M.9
Young, L.E.10
Zhong, S.11
Bailey, M.12
White, J.R.13
Roels, S.14
Deffenbaugh, J.15
Fichtenholtz, A.16
Brennan, T.17
Rosenzweig, M.18
Pelak, K.19
Knapp, K.M.20
Brennan, K.W.21
Donahue, A.L.22
Young, G.23
Garcia, L.24
Beckstrom, S.T.25
Zhao, M.26
White, E.27
Banning, V.28
Buell, J.29
Iwanik, K.30
Ross, J.S.31
Morosini, D.32
Younes, A.33
Hanash, A.M.34
Paietta, E.35
Roberts, K.36
Mullighan, C.37
Dogan, A.38
Armstrong, S.A.39
Mughal, T.40
Vergilio, J.A.41
Labrecque, E.42
Erlich, R.43
Vietz, C.44
Yelensky, R.45
Stephens, P.J.46
Miller, V.A.47
van den Brink, M.R.48
Otto, G.A.49
Lipson, D.50
Levine, R.L.51
more..
-
127
-
-
84964749942
-
Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol
-
Meric-Bernstam, F., Brusco, L., Daniels, M., Wathoo, C., Bailey, A.M., Strong, L., Shaw, K., Lu, K., Qi, Y., Zhao, H., Lara-Guerra, H., Litton, J., Arun, B., Eterovic, A.K., Aytac, U., Routbort, M., Subbiah, V., Janku, F., Davies, M.A., Kopetz, S., Mendelsohn, J., Mills, G.B., Chen, K., Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol. Ann. Oncol. 27 (2016), 795–800.
-
(2016)
Ann. Oncol.
, vol.27
, pp. 795-800
-
-
Meric-Bernstam, F.1
Brusco, L.2
Daniels, M.3
Wathoo, C.4
Bailey, A.M.5
Strong, L.6
Shaw, K.7
Lu, K.8
Qi, Y.9
Zhao, H.10
Lara-Guerra, H.11
Litton, J.12
Arun, B.13
Eterovic, A.K.14
Aytac, U.15
Routbort, M.16
Subbiah, V.17
Janku, F.18
Davies, M.A.19
Kopetz, S.20
Mendelsohn, J.21
Mills, G.B.22
Chen, K.23
more..
-
128
-
-
85010926514
-
Tumor evolutionary principles: how intratumor heterogeneity influences cancer treatment and outcome
-
Venkatesan, S., Swanton, C., Tumor evolutionary principles: how intratumor heterogeneity influences cancer treatment and outcome. Am. Soc. Clin. Oncol. Educ. Book 35 (2016), e141–e149.
-
(2016)
Am. Soc. Clin. Oncol. Educ. Book
, vol.35
, pp. e141-e149
-
-
Venkatesan, S.1
Swanton, C.2
-
129
-
-
84881476503
-
High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma
-
Mroz, E.A., Tward, A.D., Pickering, C.R., Myers, J.N., Ferris, R.L., Rocco, J.W., High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma. Cancer 119 (2013), 3034–3042.
-
(2013)
Cancer
, vol.119
, pp. 3034-3042
-
-
Mroz, E.A.1
Tward, A.D.2
Pickering, C.R.3
Myers, J.N.4
Ferris, R.L.5
Rocco, J.W.6
-
130
-
-
78649248733
-
A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma
-
Merlo, L.M.F., Shah, N.A., Li, X., Blount, P.L., Vaughan, T.L., Reid, B.J., Maley, C.C., A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma. Cancer Prev. Res. 3 (2010), 1388–1397.
-
(2010)
Cancer Prev. Res.
, vol.3
, pp. 1388-1397
-
-
Merlo, L.M.F.1
Shah, N.A.2
Li, X.3
Blount, P.L.4
Vaughan, T.L.5
Reid, B.J.6
Maley, C.C.7
-
131
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman, J.A., Zejnullahu, K., Mitsudomi, T., Song, Y., Hyland, C., Park, J.O., Lindeman, N., Gale, C.M., Zhao, X., Christensen, J., Kosaka, T., Holmes, A.J., Rogers, A.M., Cappuzzo, F., Mok, T., Lee, C., Johnson, B.E., Cantley, L.C., Janne, P.A., MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316 (2007), 1039–1043.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
Park, J.O.6
Lindeman, N.7
Gale, C.M.8
Zhao, X.9
Christensen, J.10
Kosaka, T.11
Holmes, A.J.12
Rogers, A.M.13
Cappuzzo, F.14
Mok, T.15
Lee, C.16
Johnson, B.E.17
Cantley, L.C.18
Janne, P.A.19
-
132
-
-
78650303507
-
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
-
Nazarian, R., Shi, H., Wang, Q., Kong, X., Koya, R.C., Lee, H., Chen, Z., Lee, M.K., Attar, N., Sazegar, H., Chodon, T., Nelson, S.F., McArthur, G., Sosman, J.A., Ribas, A., Lo, R.S., Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. Nature 468 (2010), 973–977.
-
(2010)
Nature
, vol.468
, pp. 973-977
-
-
Nazarian, R.1
Shi, H.2
Wang, Q.3
Kong, X.4
Koya, R.C.5
Lee, H.6
Chen, Z.7
Lee, M.K.8
Attar, N.9
Sazegar, H.10
Chodon, T.11
Nelson, S.F.12
McArthur, G.13
Sosman, J.A.14
Ribas, A.15
Lo, R.S.16
-
133
-
-
78751569531
-
Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer
-
Cooke, S.L., Temple, J., Macarthur, S., Zahra, M.A., Tan, L.T., Crawford, R.A., Ng, C.K., Jimenez-Linan, M., Sala, E., Brenton, J.D., Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer. Br. J. Cancer 104 (2011), 361–368.
-
(2011)
Br. J. Cancer
, vol.104
, pp. 361-368
-
-
Cooke, S.L.1
Temple, J.2
Macarthur, S.3
Zahra, M.A.4
Tan, L.T.5
Crawford, R.A.6
Ng, C.K.7
Jimenez-Linan, M.8
Sala, E.9
Brenton, J.D.10
-
134
-
-
84875211731
-
Cancer heterogeneity: implications for targeted therapeutics
-
Fisher, R., Pusztai, L., Swanton, C., Cancer heterogeneity: implications for targeted therapeutics. Br. J. Cancer 108 (2013), 479–485.
-
(2013)
Br. J. Cancer
, vol.108
, pp. 479-485
-
-
Fisher, R.1
Pusztai, L.2
Swanton, C.3
-
135
-
-
84905370049
-
Tracking genomic cancer evolution for precision medicine: the lung TRACERx study
-
Jamal-Hanjani, M., Hackshaw, A., Ngai, Y., Shaw, J., Dive, C., Quezada, S., Middleton, G., de Bruin, E., Le Quesne, J., Shafi, S., Falzon, M., Horswell, S., Blackhall, F., Khan, I., Janes, S., Nicolson, M., Lawrence, D., Forster, M., Fennell, D., Lee, S.M., Lester, J., Kerr, K., Muller, S., Iles, N., Smith, S., Murugaesu, N., Mitter, R., Salm, M., Stuart, A., Matthews, N., Adams, H., Ahmad, T., Attanoos, R., Bennett, J., Birkbak, N.J., Booton, R., Brady, G., Buchan, K., Capitano, A., Chetty, M., Cobbold, M., Crosbie, P., Davies, H., Denison, A., Djearman, M., Goldman, J., Haswell, T., Joseph, L., Kornaszewska, M., Krebs, M., Langman, G., MacKenzie, M., Millar, J., Morgan, B., Naidu, B., Nonaka, D., Peggs, K., Pritchard, C., Remmen, H., Rowan, A., Shah, R., Smith, E., Summers, Y., Taylor, M., Veeriah, S., Waller, D., Wilcox, B., Wilcox, M., Woolhouse, I., McGranahan, N., Swanton, C., Tracking genomic cancer evolution for precision medicine: the lung TRACERx study. PLoS Biol., 12, 2014, e1001906.
-
(2014)
PLoS Biol.
, vol.12
-
-
Jamal-Hanjani, M.1
Hackshaw, A.2
Ngai, Y.3
Shaw, J.4
Dive, C.5
Quezada, S.6
Middleton, G.7
de Bruin, E.8
Le Quesne, J.9
Shafi, S.10
Falzon, M.11
Horswell, S.12
Blackhall, F.13
Khan, I.14
Janes, S.15
Nicolson, M.16
Lawrence, D.17
Forster, M.18
Fennell, D.19
Lee, S.M.20
Lester, J.21
Kerr, K.22
Muller, S.23
Iles, N.24
Smith, S.25
Murugaesu, N.26
Mitter, R.27
Salm, M.28
Stuart, A.29
Matthews, N.30
Adams, H.31
Ahmad, T.32
Attanoos, R.33
Bennett, J.34
Birkbak, N.J.35
Booton, R.36
Brady, G.37
Buchan, K.38
Capitano, A.39
Chetty, M.40
Cobbold, M.41
Crosbie, P.42
Davies, H.43
Denison, A.44
Djearman, M.45
Goldman, J.46
Haswell, T.47
Joseph, L.48
Kornaszewska, M.49
Krebs, M.50
Langman, G.51
MacKenzie, M.52
Millar, J.53
Morgan, B.54
Naidu, B.55
Nonaka, D.56
Peggs, K.57
Pritchard, C.58
Remmen, H.59
Rowan, A.60
Shah, R.61
Smith, E.62
Summers, Y.63
Taylor, M.64
Veeriah, S.65
Waller, D.66
Wilcox, B.67
Wilcox, M.68
Woolhouse, I.69
McGranahan, N.70
Swanton, C.71
more..
-
136
-
-
85020872557
-
Re-evaluating clonal dominance in cancer evolution
-
Burrell, R.A., Swanton, C., Re-evaluating clonal dominance in cancer evolution. Trends Cancer 64 (2016), 1–14.
-
(2016)
Trends Cancer
, vol.64
, pp. 1-14
-
-
Burrell, R.A.1
Swanton, C.2
-
137
-
-
84928823799
-
Can oncology recapitulate paleontology? Lessons from species extinctions
-
Walther, V., Hiley, C.T., Shibata, D., Swanton, C., Turner, P.E., Maley, C.C., Can oncology recapitulate paleontology? Lessons from species extinctions. Nat. Rev. Clin. Oncol. 12 (2015), 273–285.
-
(2015)
Nat. Rev. Clin. Oncol.
, vol.12
, pp. 273-285
-
-
Walther, V.1
Hiley, C.T.2
Shibata, D.3
Swanton, C.4
Turner, P.E.5
Maley, C.C.6
-
138
-
-
82955169663
-
Evolutionary dynamics in cancer therapy
-
Cunningham, J.J., Gatenby, R.A., Brown, J.S., Evolutionary dynamics in cancer therapy. Mol. Pharm. 8 (2011), 2094–2100.
-
(2011)
Mol. Pharm.
, vol.8
, pp. 2094-2100
-
-
Cunningham, J.J.1
Gatenby, R.A.2
Brown, J.S.3
-
139
-
-
32944468708
-
Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer
-
Antonia, S.J., Mirza, N., Fricke, I., Chiappori, A., Thompson, P., Williams, N., Bepler, G., Simon, G., Janssen, W., Lee, J.H., Menander, K., Chada, S., Gabrilovich, D.I., Combination of p53 cancer vaccine with chemotherapy in patients with extensive stage small cell lung cancer. Clin. Cancer Res. 12 (2006), 878–887.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 878-887
-
-
Antonia, S.J.1
Mirza, N.2
Fricke, I.3
Chiappori, A.4
Thompson, P.5
Williams, N.6
Bepler, G.7
Simon, G.8
Janssen, W.9
Lee, J.H.10
Menander, K.11
Chada, S.12
Gabrilovich, D.I.13
-
140
-
-
0035404535
-
Evolving responsively: adaptive mutation
-
Rosenberg, S.M., Evolving responsively: adaptive mutation. Nat. Rev. Genet. 2 (2001), 504–515.
-
(2001)
Nat. Rev. Genet.
, vol.2
, pp. 504-515
-
-
Rosenberg, S.M.1
-
141
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden, M.G., Cantley, L.C., Thompson, C.B., Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324 (2009), 1029–1033.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
142
-
-
84863661689
-
Therapeutic targets in cancer cell metabolism and autophagy
-
Cheong, H., Lu, C., Lindsten, T., Thompson, C.B., Therapeutic targets in cancer cell metabolism and autophagy. Nat. Biotechnol. 30 (2012), 671–678.
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 671-678
-
-
Cheong, H.1
Lu, C.2
Lindsten, T.3
Thompson, C.B.4
-
143
-
-
34447094919
-
Glycolysis in cancer: a potential target for therapy
-
Gatenby, R.A., Gillies, R.J., Glycolysis in cancer: a potential target for therapy. Int. J. Biochem. Cell Biol. 39 (2007), 1358–1366.
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 1358-1366
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
144
-
-
84955465654
-
Application of evolutionary principles to cancer therapy
-
Enriquez-Navas, P.M., Wojtkowiak, J.W., Gatenby, R.A., Application of evolutionary principles to cancer therapy. Cancer Res. 75 (2015), 4675–4680.
-
(2015)
Cancer Res.
, vol.75
, pp. 4675-4680
-
-
Enriquez-Navas, P.M.1
Wojtkowiak, J.W.2
Gatenby, R.A.3
-
145
-
-
66349121917
-
Adaptive therapy
-
Gatenby, R.A., Silva, A.S., Gillies, R.J., Frieden, B.R., Adaptive therapy. Cancer Res. 69 (2009), 4894–4903.
-
(2009)
Cancer Res.
, vol.69
, pp. 4894-4903
-
-
Gatenby, R.A.1
Silva, A.S.2
Gillies, R.J.3
Frieden, B.R.4
-
146
-
-
84907479178
-
Evolutionary strategy for systemic therapy of metastatic breast cancer: balancing response with suppression of resistance
-
Kam, Y., Das, T., Minton, S., Gatenby, R.A., Evolutionary strategy for systemic therapy of metastatic breast cancer: balancing response with suppression of resistance. Women Health 10 (2014), 423–430.
-
(2014)
Women Health
, vol.10
, pp. 423-430
-
-
Kam, Y.1
Das, T.2
Minton, S.3
Gatenby, R.A.4
-
147
-
-
84959450201
-
Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer
-
Enriquez-Navas, P.M., Kam, Y., Das, T., Hassan, S., Silva, A., Foroutan, P., Ruiz, E., Martinez, G., Minton, S., Gillies, R.J., Gatenby, R.A., Exploiting evolutionary principles to prolong tumor control in preclinical models of breast cancer. Sci. Transl. Med., 8, 2016, 327-324.
-
(2016)
Sci. Transl. Med.
, vol.8
, pp. 327-324
-
-
Enriquez-Navas, P.M.1
Kam, Y.2
Das, T.3
Hassan, S.4
Silva, A.5
Foroutan, P.6
Ruiz, E.7
Martinez, G.8
Minton, S.9
Gillies, R.J.10
Gatenby, R.A.11
-
148
-
-
68949180445
-
Metronomic chemotherapy: changing the paradigm that more is better
-
Scharovsky, O.G., Mainetti, L.E., Rozados, V.R., Metronomic chemotherapy: changing the paradigm that more is better. Curr. Oncol. 16 (2009), 7–15.
-
(2009)
Curr. Oncol.
, vol.16
, pp. 7-15
-
-
Scharovsky, O.G.1
Mainetti, L.E.2
Rozados, V.R.3
-
149
-
-
2942615257
-
The anti-angiogenic basis of metronomic chemotherapy
-
Kerbel, R.S., Kamen, B.A., The anti-angiogenic basis of metronomic chemotherapy. Nat. Rev. Cancer 4 (2004), 423–436.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
-
150
-
-
84901001797
-
Metronomics as maintenance treatment in oncology: time for chemo-switch
-
Malik, P.S., Raina, V., Andre, N., Metronomics as maintenance treatment in oncology: time for chemo-switch. Front. Oncol., 4, 2014, 76.
-
(2014)
Front. Oncol.
, vol.4
, pp. 76
-
-
Malik, P.S.1
Raina, V.2
Andre, N.3
-
151
-
-
67149143399
-
Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive, K.P., Jacobetz, M.A., Davidson, C.J., Gopinathan, A., McIntyre, D., Honess, D., Madhu, B., Goldgraben, M.A., Caldwell, M.E., Allard, D., Frese, K.K., Denicola, G., Feig, C., Combs, C., Winter, S.P., Ireland-Zecchini, H., Reichelt, S., Howat, W.J., Chang, A., Dhara, M., Wang, L., Ruckert, F., Grutzmann, R., Pilarsky, C., Izeradjene, K., Hingorani, S.R., Huang, P., Davies, S.E., Plunkett, W., Egorin, M., Hruban, R.H., Whitebread, N., McGovern, K., Adams, J., Iacobuzio-Donahue, C., Griffiths, J., Tuveson, D.A., Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324 (2009), 1457–1461.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
Frese, K.K.11
Denicola, G.12
Feig, C.13
Combs, C.14
Winter, S.P.15
Ireland-Zecchini, H.16
Reichelt, S.17
Howat, W.J.18
Chang, A.19
Dhara, M.20
Wang, L.21
Ruckert, F.22
Grutzmann, R.23
Pilarsky, C.24
Izeradjene, K.25
Hingorani, S.R.26
Huang, P.27
Davies, S.E.28
Plunkett, W.29
Egorin, M.30
Hruban, R.H.31
Whitebread, N.32
McGovern, K.33
Adams, J.34
Iacobuzio-Donahue, C.35
Griffiths, J.36
Tuveson, D.A.37
more..
-
152
-
-
0037192458
-
Matrix metalloproteinase inhibitors and cancer: trials and tribulations
-
Coussens, L.M., Fingleton, B., Matrisian, L.M., Matrix metalloproteinase inhibitors and cancer: trials and tribulations. Science 295 (2002), 2387–2392.
-
(2002)
Science
, vol.295
, pp. 2387-2392
-
-
Coussens, L.M.1
Fingleton, B.2
Matrisian, L.M.3
-
153
-
-
84923952286
-
A Big Bang model of human colorectal tumor growth
-
Sottoriva, A., Kang, H., Ma, Z., Graham, T.A., Salomon, M.P., Zhao, J., Marjoram, P., Siegmund, K., Press, M.F., Shibata, D., Curtis, C., A Big Bang model of human colorectal tumor growth. Nat. Genet. 47 (2015), 209–216.
-
(2015)
Nat. Genet.
, vol.47
, pp. 209-216
-
-
Sottoriva, A.1
Kang, H.2
Ma, Z.3
Graham, T.A.4
Salomon, M.P.5
Zhao, J.6
Marjoram, P.7
Siegmund, K.8
Press, M.F.9
Shibata, D.10
Curtis, C.11
-
154
-
-
84866950018
-
The promise of patient-derived xenografts: the best laid plans of mice and men
-
Kopetz, S., Lemos, R., Powis, G., The promise of patient-derived xenografts: the best laid plans of mice and men. Clin. Cancer Res. 18 (2012), 5160–5162.
-
(2012)
Clin. Cancer Res.
, vol.18
, pp. 5160-5162
-
-
Kopetz, S.1
Lemos, R.2
Powis, G.3
-
155
-
-
84891354380
-
Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients
-
Ni, X., Zhuo, M., Su, Z., Duan, J., Gao, Y., Wang, Z., Zong, C., Bai, H., Chapman, A.R., Zhao, J., Xu, L., An, T., Ma, Q., Wang, Y., Wu, M., Sun, Y., Wang, S., Li, Z., Yang, X., Yong, J., Su, X.D., Lu, Y., Bai, F., Xie, X.S., Wang, J., Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), 21083–21088.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 21083-21088
-
-
Ni, X.1
Zhuo, M.2
Su, Z.3
Duan, J.4
Gao, Y.5
Wang, Z.6
Zong, C.7
Bai, H.8
Chapman, A.R.9
Zhao, J.10
Xu, L.11
An, T.12
Ma, Q.13
Wang, Y.14
Wu, M.15
Sun, Y.16
Wang, S.17
Li, Z.18
Yang, X.19
Yong, J.20
Su, X.D.21
Lu, Y.22
Bai, F.23
Xie, X.S.24
Wang, J.25
more..
-
156
-
-
84900333051
-
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
-
Lohr, J.G., Adalsteinsson, V.A., Cibulskis, K., Choudhury, A.D., Rosenberg, M., Cruz-Gordillo, P., Francis, J.M., Zhang, C.Z., Shalek, A.K., Satija, R., Trombetta, J.J., Lu, D., Tallapragada, N., Tahirova, N., Kim, S., Blumenstiel, B., Sougnez, C., Lowe, A., Wong, B., Auclair, D., Van Allen, E.M., Nakabayashi, M., Lis, R.T., Lee, G.S., Li, T., Chabot, M.S., Ly, A., Taplin, M.E., Clancy, T.E., Loda, M., Regev, A., Meyerson, M., Hahn, W.C., Kantoff, P.W., Golub, T.R., Getz, G., Boehm, J.S., Love, J.C., Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer. Nat. Biotechnol. 32 (2014), 479–484.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 479-484
-
-
Lohr, J.G.1
Adalsteinsson, V.A.2
Cibulskis, K.3
Choudhury, A.D.4
Rosenberg, M.5
Cruz-Gordillo, P.6
Francis, J.M.7
Zhang, C.Z.8
Shalek, A.K.9
Satija, R.10
Trombetta, J.J.11
Lu, D.12
Tallapragada, N.13
Tahirova, N.14
Kim, S.15
Blumenstiel, B.16
Sougnez, C.17
Lowe, A.18
Wong, B.19
Auclair, D.20
Van Allen, E.M.21
Nakabayashi, M.22
Lis, R.T.23
Lee, G.S.24
Li, T.25
Chabot, M.S.26
Ly, A.27
Taplin, M.E.28
Clancy, T.E.29
Loda, M.30
Regev, A.31
Meyerson, M.32
Hahn, W.C.33
Kantoff, P.W.34
Golub, T.R.35
Getz, G.36
Boehm, J.S.37
Love, J.C.38
more..
-
157
-
-
84907342688
-
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis
-
Aceto, N., Bardia, A., Miyamoto, D.T., Donaldson, M.C., Wittner, B.S., Spencer, J.A., Yu, M., Pely, A., Engstrom, A., Zhu, H., Brannigan, B.W., Kapur, R., Stott, S.L., Shioda, T., Ramaswamy, S., Ting, D.T., Lin, C.P., Toner, M., Haber, D.A., Maheswaran, S., Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell 158 (2014), 1110–1122.
-
(2014)
Cell
, vol.158
, pp. 1110-1122
-
-
Aceto, N.1
Bardia, A.2
Miyamoto, D.T.3
Donaldson, M.C.4
Wittner, B.S.5
Spencer, J.A.6
Yu, M.7
Pely, A.8
Engstrom, A.9
Zhu, H.10
Brannigan, B.W.11
Kapur, R.12
Stott, S.L.13
Shioda, T.14
Ramaswamy, S.15
Ting, D.T.16
Lin, C.P.17
Toner, M.18
Haber, D.A.19
Maheswaran, S.20
more..
-
158
-
-
84896371874
-
Detection of circulating tumor DNA in early- and late-stage human malignancies
-
(224ra224-224ra224)
-
Bettegowda, C., Sausen, M., Leary, R.J., Kinde, I., Wang, Y., Agrawal, N., Bartlett, B.R., Wang, H., Luber, B., Alani, R.M., Antonarakis, E.S., Azad, N.S., Bardelli, A., Brem, H., Cameron, J.L., Lee, C.C., Fecher, L.A., Gallia, G.L., Gibbs, P., Le, D., Giuntoli, R.L., Goggins, M., Hogarty, M.D., Holdhoff, M., Hong, S.-M., Jiao, Y., Juhl, H.H., Kim, J.J., Siravegna, G., Laheru, D.A., Lauricella, C., Lim, M., Lipson, E.J., Marie, S.K.N., Netto, G.J., Oliner, K.S., Olivi, A., Olsson, L., Riggins, G.J., Sartore-Bianchi, A., Schmidt, K., Shih, L.-M., Oba-Shinjo, S.M., Siena, S., Theodorescu, D., Tie, J., Harkins, T.T., Veronese, S., Wang, T.-L., Weingart, J.D., Wolfgang, C.L., Wood, L.D., Xing, D., Hruban, R.H., Wu, J., Allen, P.J., Schmidt, C.M., Choti, M.A., Velculescu, V.E., Kinzler, K.W., Vogelstein, B., Papadopoulos, N., Diaz, L.A., Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci. Transl. Med., 6, 2014 (224ra224-224ra224).
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Bettegowda, C.1
Sausen, M.2
Leary, R.J.3
Kinde, I.4
Wang, Y.5
Agrawal, N.6
Bartlett, B.R.7
Wang, H.8
Luber, B.9
Alani, R.M.10
Antonarakis, E.S.11
Azad, N.S.12
Bardelli, A.13
Brem, H.14
Cameron, J.L.15
Lee, C.C.16
Fecher, L.A.17
Gallia, G.L.18
Gibbs, P.19
Le, D.20
Giuntoli, R.L.21
Goggins, M.22
Hogarty, M.D.23
Holdhoff, M.24
Hong, S.-M.25
Jiao, Y.26
Juhl, H.H.27
Kim, J.J.28
Siravegna, G.29
Laheru, D.A.30
Lauricella, C.31
Lim, M.32
Lipson, E.J.33
Marie, S.K.N.34
Netto, G.J.35
Oliner, K.S.36
Olivi, A.37
Olsson, L.38
Riggins, G.J.39
Sartore-Bianchi, A.40
Schmidt, K.41
Shih, L.-M.42
Oba-Shinjo, S.M.43
Siena, S.44
Theodorescu, D.45
Tie, J.46
Harkins, T.T.47
Veronese, S.48
Wang, T.-L.49
Weingart, J.D.50
Wolfgang, C.L.51
Wood, L.D.52
Xing, D.53
Hruban, R.H.54
Wu, J.55
Allen, P.J.56
Schmidt, C.M.57
Choti, M.A.58
Velculescu, V.E.59
Kinzler, K.W.60
Vogelstein, B.61
Papadopoulos, N.62
Diaz, L.A.63
more..
-
159
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
Dawson, S.J., Tsui, D.W., Murtaza, M., Biggs, H., Rueda, O.M., Chin, S.F., Dunning, M.J., Gale, D., Forshew, T., Mahler-Araujo, B., Rajan, S., Humphray, S., Becq, J., Halsall, D., Wallis, M., Bentley, D., Caldas, C., Rosenfeld, N., Analysis of circulating tumor DNA to monitor metastatic breast cancer. N. Engl. J. Med. 368 (2013), 1199–1209.
-
(2013)
N. Engl. J. Med.
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
Tsui, D.W.2
Murtaza, M.3
Biggs, H.4
Rueda, O.M.5
Chin, S.F.6
Dunning, M.J.7
Gale, D.8
Forshew, T.9
Mahler-Araujo, B.10
Rajan, S.11
Humphray, S.12
Becq, J.13
Halsall, D.14
Wallis, M.15
Bentley, D.16
Caldas, C.17
Rosenfeld, N.18
-
160
-
-
84903218109
-
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
-
Newman, A.M., Bratman, S.V., J. To, Wynne, J.F., Eclov, N.C., Modlin, L.A., Liu, C.L., Neal, J.W., Wakelee, H.A., Merritt, R.E., Shrager, J.B., Loo, B.W. Jr., Alizadeh, A.A., Diehn, M., An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage. Nat. Med. 20 (2014), 548–554.
-
(2014)
Nat. Med.
, vol.20
, pp. 548-554
-
-
Newman, A.M.1
Bratman, S.V.2
To, J.3
Wynne, J.F.4
Eclov, N.C.5
Modlin, L.A.6
Liu, C.L.7
Neal, J.W.8
Wakelee, H.A.9
Merritt, R.E.10
Shrager, J.B.11
Loo, B.W.12
Alizadeh, A.A.13
Diehn, M.14
-
161
-
-
84949009842
-
Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA
-
Lanman, R.B., Mortimer, S.A., Zill, O.A., Sebisanovic, D., Lopez, R., Blau, S., Collisson, E.A., Divers, S.G., Hoon, D.S., Kopetz, E.S., Lee, J., Nikolinakos, P.G., Baca, A.M., Kermani, B.G., Eltoukhy, H., Talasaz, A., Analytical and clinical validation of a digital sequencing panel for quantitative, highly accurate evaluation of cell-free circulating tumor DNA. PLoS One, 10, 2015, e0140712.
-
(2015)
PLoS One
, vol.10
-
-
Lanman, R.B.1
Mortimer, S.A.2
Zill, O.A.3
Sebisanovic, D.4
Lopez, R.5
Blau, S.6
Collisson, E.A.7
Divers, S.G.8
Hoon, D.S.9
Kopetz, E.S.10
Lee, J.11
Nikolinakos, P.G.12
Baca, A.M.13
Kermani, B.G.14
Eltoukhy, H.15
Talasaz, A.16
-
162
-
-
84946559772
-
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer
-
Murtaza, M., Dawson, S.J., Pogrebniak, K., Rueda, O.M., Provenzano, E., Grant, J., Chin, S.F., Tsui, D.W., Marass, F., Gale, D., Ali, H.R., Shah, P., Contente-Cuomo, T., Farahani, H., Shumansky, K., Kingsbury, Z., Humphray, S., Bentley, D., Shah, S.P., Wallis, M., Rosenfeld, N., Caldas, C., Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer. Nat. Commun., 6, 2015, 8760.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8760
-
-
Murtaza, M.1
Dawson, S.J.2
Pogrebniak, K.3
Rueda, O.M.4
Provenzano, E.5
Grant, J.6
Chin, S.F.7
Tsui, D.W.8
Marass, F.9
Gale, D.10
Ali, H.R.11
Shah, P.12
Contente-Cuomo, T.13
Farahani, H.14
Shumansky, K.15
Kingsbury, Z.16
Humphray, S.17
Bentley, D.18
Shah, S.P.19
Wallis, M.20
Rosenfeld, N.21
Caldas, C.22
more..
-
163
-
-
84943328606
-
Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease
-
Butler, T.M., Johnson-Camacho, K., Peto, M., Wang, N.J., Macey, T.A., Korkola, J.E., Koppie, T.M., Corless, C.L., Gray, J.W., Spellman, P.T., Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease. PLoS One, 10, 2015, e0136407.
-
(2015)
PLoS One
, vol.10
-
-
Butler, T.M.1
Johnson-Camacho, K.2
Peto, M.3
Wang, N.J.4
Macey, T.A.5
Korkola, J.E.6
Koppie, T.M.7
Corless, C.L.8
Gray, J.W.9
Spellman, P.T.10
-
164
-
-
77951139631
-
Genome remodelling in a basal-like breast cancer metastasis and xenograft
-
Ding, L., Ellis, M.J., Li, S., Larson, D.E., Chen, K., Wallis, J.W., Harris, C.C., McLellan, M.D., Fulton, R.S., Fulton, L.L., Abbott, R.M., Hoog, J., Dooling, D.J., Koboldt, D.C., Schmidt, H., Kalicki, J., Zhang, Q., Chen, L., Lin, L., Wendl, M.C., McMichael, J.F., Magrini, V.J., Cook, L., McGrath, S.D., Vickery, T.L., Appelbaum, E., Deschryver, K., Davies, S., Guintoli, T., Crowder, R., Tao, Y., Snider, J.E., Smith, S.M., Dukes, A.F., Sanderson, G.E., Pohl, C.S., Delehaunty, K.D., Fronick, C.C., Pape, K.A., Reed, J.S., Robinson, J.S., Hodges, J.S., Schierding, W., Dees, N.D., Shen, D., Locke, D.P., Wiechert, M.E., Eldred, J.M., Peck, J.B., Oberkfell, B.J., Lolofie, J.T., Du, F., Hawkins, A.E., O'Laughlin, M.D., Bernard, K.E., Cunningham, M., Elliott, G., Mason, M.D., Thompson, D.M. Jr., Ivanovich, J.L., Goodfellow, P.J., Perou, C.M., Weinstock, G.M., Aft, R., Watson, M., Ley, T.J., Wilson, R.K., Mardis, E.R., Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464 (2010), 999–1005.
-
(2010)
Nature
, vol.464
, pp. 999-1005
-
-
Ding, L.1
Ellis, M.J.2
Li, S.3
Larson, D.E.4
Chen, K.5
Wallis, J.W.6
Harris, C.C.7
McLellan, M.D.8
Fulton, R.S.9
Fulton, L.L.10
Abbott, R.M.11
Hoog, J.12
Dooling, D.J.13
Koboldt, D.C.14
Schmidt, H.15
Kalicki, J.16
Zhang, Q.17
Chen, L.18
Lin, L.19
Wendl, M.C.20
McMichael, J.F.21
Magrini, V.J.22
Cook, L.23
McGrath, S.D.24
Vickery, T.L.25
Appelbaum, E.26
Deschryver, K.27
Davies, S.28
Guintoli, T.29
Crowder, R.30
Tao, Y.31
Snider, J.E.32
Smith, S.M.33
Dukes, A.F.34
Sanderson, G.E.35
Pohl, C.S.36
Delehaunty, K.D.37
Fronick, C.C.38
Pape, K.A.39
Reed, J.S.40
Robinson, J.S.41
Hodges, J.S.42
Schierding, W.43
Dees, N.D.44
Shen, D.45
Locke, D.P.46
Wiechert, M.E.47
Eldred, J.M.48
Peck, J.B.49
Oberkfell, B.J.50
Lolofie, J.T.51
Du, F.52
Hawkins, A.E.53
O'Laughlin, M.D.54
Bernard, K.E.55
Cunningham, M.56
Elliott, G.57
Mason, M.D.58
Thompson, D.M.59
Ivanovich, J.L.60
Goodfellow, P.J.61
Perou, C.M.62
Weinstock, G.M.63
Aft, R.64
Watson, M.65
Ley, T.J.66
Wilson, R.K.67
Mardis, E.R.68
more..
-
165
-
-
77950592442
-
Establishment and genomic characterization of mouse xenografts of human primary prostate tumors
-
Priolo, C., Agostini, M., Vena, N., Ligon, A.H., Fiorentino, M., Shin, E., Farsetti, A., Pontecorvi, A., Sicinska, E., Loda, M., Establishment and genomic characterization of mouse xenografts of human primary prostate tumors. Am. J. Pathol. 176 (2010), 1901–1913.
-
(2010)
Am. J. Pathol.
, vol.176
, pp. 1901-1913
-
-
Priolo, C.1
Agostini, M.2
Vena, N.3
Ligon, A.H.4
Fiorentino, M.5
Shin, E.6
Farsetti, A.7
Pontecorvi, A.8
Sicinska, E.9
Loda, M.10
-
166
-
-
84884597613
-
Next-generation sequence analysis of cancer xenograft models
-
Rossello, F.J., Tothill, R.W., Britt, K., Marini, K.D., Falzon, J., Thomas, D.M., Peacock, C.D., Marchionni, L., Li, J., Bennett, S., Tantoso, E., Brown, T., Chan, P., Martelotto, L.G., Watkins, D.N., Next-generation sequence analysis of cancer xenograft models. PLoS One, 8, 2013, e74432.
-
(2013)
PLoS One
, vol.8
-
-
Rossello, F.J.1
Tothill, R.W.2
Britt, K.3
Marini, K.D.4
Falzon, J.5
Thomas, D.M.6
Peacock, C.D.7
Marchionni, L.8
Li, J.9
Bennett, S.10
Tantoso, E.11
Brown, T.12
Chan, P.13
Martelotto, L.G.14
Watkins, D.N.15
-
167
-
-
84943151088
-
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
-
Eirew, P., Steif, A., Khattra, J., Ha, G., Yap, D., Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution. Nature, 2014.
-
(2014)
Nature
-
-
Eirew, P.1
Steif, A.2
Khattra, J.3
Ha, G.4
Yap, D.5
-
168
-
-
84906895091
-
Patient-derived xenograft models: an emerging platform for translational cancer research
-
Hidalgo, M., Amant, F., Biankin, A.V., Budinska, E., Byrne, A.T., Caldas, C., Clarke, R.B., de Jong, S., Jonkers, J., Maelandsmo, G.M., Roman-Roman, S., Seoane, J., Trusolino, L., Villanueva, A., Patient-derived xenograft models: an emerging platform for translational cancer research. Cancer Discov. 4 (2014), 998–1013.
-
(2014)
Cancer Discov.
, vol.4
, pp. 998-1013
-
-
Hidalgo, M.1
Amant, F.2
Biankin, A.V.3
Budinska, E.4
Byrne, A.T.5
Caldas, C.6
Clarke, R.B.7
de Jong, S.8
Jonkers, J.9
Maelandsmo, G.M.10
Roman-Roman, S.11
Seoane, J.12
Trusolino, L.13
Villanueva, A.14
|