Mutator phenotype in cancer: Timing and perspectives

Environmental and Molecular Mutagenesis

Volumn 45, Issue 2-3, 2005, Pages 206-213

  Bielas, Jason H ^a   Loeb, Lawrence A ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cancer treatment; Clonal expansion; DNA repair; Metastasis

Indexed keywords

ANTINEOPLASTIC AGENT; BETA GALACTOSIDASE; HELICASE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; IMMUNOMODULATING AGENT; MUTAGENIC AGENT; NUCLEOTIDE; REACTIVE OXYGEN METABOLITE; TISSUE FACTOR PATHWAY INHIBITOR;

AMINO ACID SUBSTITUTION; BARRETT ESOPHAGUS; BONE MARROW; BREAST CARCINOMA; CALORIC RESTRICTION; CANCER CELL; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER PREVENTION; CARCINOGENESIS; CHROMOSOME ABERRATION; COLON POLYPOSIS; COLORECTAL CANCER; COMPARATIVE GENOMIC HYBRIDIZATION; DNA REPAIR; DNA REPLICATION; DNA SEQUENCE; DNA STRUCTURE; GENE MUTATION; GENE REPLICATION; HETEROZYGOSITY; HETEROZYGOSITY LOSS; HUMAN; IMMUNOTHERAPY; MELANOMA; METASTASIS; MISMATCH REPAIR; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POLYMERASE CHAIN REACTION; REVIEW; SIGNAL TRANSDUCTION; STEM CELL; TRANSGENE; TUMOR GROWTH; TUMOR SUPPRESSOR GENE; ULCERATIVE COLITIS;

DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, GENETIC; MUTATION; NEOPLASM METASTASIS; NEOPLASMS; PHENOTYPE;

EID: 17044411374     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.20111     Document Type: Review

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