Subclonal diversification of primary breast cancer revealed by multiregion sequencing

Nature Medicine

Volumn 21, Issue 7, 2015, Pages 751-759

  Yates, Lucy R ^a,b   Gerstung, Moritz ^a   Knappskog, Stian ^c,d   Desmedt, Christine ^e   Gundem, Gunes ^a   Van Loo, Peter ^a,f   Aas, Turid ^d   Alexandrov, Ludmil B ^a,g   Larsimont, Denis ^e   Davies, Helen ^a   Li, Yilong ^a   Ju, Young Seok ^a   Ramakrishna, Manasa ^a   Haugland, Hans Kristian ^d   Lilleng, Peer Kaare ^c,d   Nik Zainal, Serena ^a   McLaren, Stuart ^a   Butler, Adam ^a   Martin, Sancha ^a   Glodzik, Dominic ^a   Menzies, Andrew ^a   Raine, Keiran ^a   Hinton, Jonathan ^a   Jones, David ^a   Mudie, Laura J ^a   Jiang, Bing ^h   Vincent, Delphine ^e   Greene Colozzi, April ^h   Adnet, Pierre Yves ^e   Fatima, Aquila ^h   Maetens, Marion ^e   Ignatiadis, Michail ^e   Stratton, Michael R ^a   Sotiriou, Christos ^e   Richardson, Andrea L ^h,i   Lønning, Per Eystein ^c,d   Wedge, David C ^a   Campbell, Peter J ^a   more..

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITY OF BERGEN   (Norway)

^d HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^e JULES BORDET INSTITUTE   (Belgium)

^f UNIVERSITY OF LEUVEN   (Belgium)

^g LOS ALAMOS NATIONAL LABORATORY   (United States)

^h DANA FARBER CANCER INSTITUTE   (United States)

ⁱ BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; BRCA2 PROTEIN; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN P53;

ADJUVANT THERAPY; ADULT; AGED; ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER GROWTH; CLINICAL ARTICLE; DISEASE COURSE; FEMALE; GENE MUTATION; GENE SEQUENCE; GENETIC HETEROGENEITY; HUMAN; METASTASIS; MULTIPLE CANCER; PRIMARY TUMOR; PRIORITY JOURNAL; BREAST NEOPLASMS; CELL CLONE; CELL PROLIFERATION; COHORT ANALYSIS; COPY NUMBER VARIATION; GENETIC VARIATION; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; MIDDLE AGED; MUTATION; PATHOLOGY; PROCEDURES; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL PROLIFERATION; CLONE CELLS; COHORT STUDIES; DNA COPY NUMBER VARIATIONS; FEMALE; GENETIC VARIATION; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MIDDLE AGED; MUTATION;

EID: 84936890500     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.3886     Document Type: Article

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