PhyloWGS: Reconstructing subclonal composition and evolution from whole-genome sequencing of tumors

Genome Biology

Volumn 16, Issue 1, 2015, Pages

  Deshwar, Amit G ^a   Vembu, Shankar ^a   Yung, Christina K ^b   Jang, Gun Ho ^b   Stein, Lincoln ^a,b   Morris, Quaid ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; AREA UNDER THE CURVE; ARTICLE; BAYES THEOREM; BREAST TUMOR; CANCER CELL; CANCER CELL LINE; CELL LINEAGE; CHRONIC LYMPHATIC LEUKEMIA; CLONAL EVOLUTION; COMPUTER PROGRAM; COPY NUMBER VARIATION; DATA ANALYSIS SOFTWARE; DIPLOIDY; EVOLUTIONARY HOMOLOGY; GENE AMPLIFICATION; GENE CONSTRUCT; GENE DELETION; GENE FREQUENCY; GENE LOCUS; GENE SEQUENCE; GENOME SIZE; GENOTYPE; HOMOZYGOSITY; HUMAN; MONTE CARLO METHOD; PARSIMONY ANALYSIS; PHYLOGENY; PROBABILITY; SOMATIC MUTATION; CELL CLONE; CLUSTER ANALYSIS; COMPUTER SIMULATION; GENETIC HETEROGENEITY; GENETICS; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME; MUTATION; NEOPLASM; PROCEDURES; STANDARD;

ALGORITHMS; CLONE CELLS; CLUSTER ANALYSIS; COMPUTER SIMULATION; DNA COPY NUMBER VARIATIONS; GENE FREQUENCY; GENETIC HETEROGENEITY; GENOME, HUMAN; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MUTATION; NEOPLASMS; PHYLOGENY; REFERENCE STANDARDS;

EID: 84935825808     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0602-8     Document Type: Article

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