-
1
-
-
84941031094
-
Organelle autoregulation–stress responses in the ER, Golgi, mitochondria and lysosome
-
[1] Sasaki, K., Yoshida, H., Organelle autoregulation–stress responses in the ER, Golgi, mitochondria and lysosome. J. Biochem. 157 (2015), 185–195.
-
(2015)
J. Biochem.
, vol.157
, pp. 185-195
-
-
Sasaki, K.1
Yoshida, H.2
-
2
-
-
84863740827
-
The impact of the unfolded protein response on human disease
-
[2] Wang, S., Kaufman, R.J., The impact of the unfolded protein response on human disease. J. Cell Biol. 197 (2012), 857–867.
-
(2012)
J. Cell Biol.
, vol.197
, pp. 857-867
-
-
Wang, S.1
Kaufman, R.J.2
-
3
-
-
84857602019
-
Crosstalk and barriers between the electron carriers of the endoplasmic reticulum
-
[3] Banhegyi, G., Margittai, E., Szarka, A., Mandl, J., Csala, M., Crosstalk and barriers between the electron carriers of the endoplasmic reticulum. Antioxid. Redox Signal. 16 (2012), 772–780.
-
(2012)
Antioxid. Redox Signal.
, vol.16
, pp. 772-780
-
-
Banhegyi, G.1
Margittai, E.2
Szarka, A.3
Mandl, J.4
Csala, M.5
-
4
-
-
84859257455
-
The endoplasmic reticulum as the extracellular space inside the cell: role in protein folding and glycosylation
-
[4] Csala, M., Kereszturi, E., Mandl, J., Banhegyi, G., The endoplasmic reticulum as the extracellular space inside the cell: role in protein folding and glycosylation. Antioxid. Redox Signal. 16 (2012), 1100–1108.
-
(2012)
Antioxid. Redox Signal.
, vol.16
, pp. 1100-1108
-
-
Csala, M.1
Kereszturi, E.2
Mandl, J.3
Banhegyi, G.4
-
5
-
-
0034724520
-
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
-
[5] Travers, K.J., Patil, C.K., Wodicka, L., Lockhart, D.J., Weissman, J.S., Walter, P., Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101 (2000), 249–258.
-
(2000)
Cell
, vol.101
, pp. 249-258
-
-
Travers, K.J.1
Patil, C.K.2
Wodicka, L.3
Lockhart, D.J.4
Weissman, J.S.5
Walter, P.6
-
6
-
-
84874112079
-
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies
-
[6] Luo, B., Lee, A.S., The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies. Oncogene 32 (2013), 805–818.
-
(2013)
Oncogene
, vol.32
, pp. 805-818
-
-
Luo, B.1
Lee, A.S.2
-
7
-
-
0025937289
-
SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane
-
[7] Wada, I., Rindress, D., Cameron, P.H., Ou, W.J., Doherty, J.J. II, Louvard, D., Bell, A.W., Dignard, D., Thomas, D.Y., Bergeron, J.J., SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane. J. Biol. Chem. 266 (1991), 19599–19610.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19599-19610
-
-
Wada, I.1
Rindress, D.2
Cameron, P.H.3
Ou, W.J.4
Doherty, J.J.5
Louvard, D.6
Bell, A.W.7
Dignard, D.8
Thomas, D.Y.9
Bergeron, J.J.10
-
8
-
-
0027156495
-
Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin)
-
[8] David, V., Hochstenbach, F., Rajagopalan, S., Brenner, M.B., Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin). J. Biol. Chem. 268 (1993), 9585–9592.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 9585-9592
-
-
David, V.1
Hochstenbach, F.2
Rajagopalan, S.3
Brenner, M.B.4
-
9
-
-
0027081774
-
Analysis in vivo of GRP78-BiP/substrate interactions and their role in induction of the GRP78-BiP gene
-
[9] Ng, D.T., Watowich, S.S., Lamb, R.A., Analysis in vivo of GRP78-BiP/substrate interactions and their role in induction of the GRP78-BiP gene. Mol. Biol. Cell 3 (1992), 143–155.
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 143-155
-
-
Ng, D.T.1
Watowich, S.S.2
Lamb, R.A.3
-
10
-
-
0033015485
-
The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis
-
[10] Yu, Z., Luo, H., Fu, W., Mattson, M.P., The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp. Neurol. 155 (1999), 302–314.
-
(1999)
Exp. Neurol.
, vol.155
, pp. 302-314
-
-
Yu, Z.1
Luo, H.2
Fu, W.3
Mattson, M.P.4
-
11
-
-
84906712846
-
The impact of the endoplasmic reticulum protein-folding environment on cancer development
-
[11] Wang, M., Kaufman, R.J., The impact of the endoplasmic reticulum protein-folding environment on cancer development. Nat. Rev. Cancer 14 (2014), 581–597.
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 581-597
-
-
Wang, M.1
Kaufman, R.J.2
-
12
-
-
0035872446
-
Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone
-
[12] Ozawa, K., Tsukamoto, Y., Hori, O., Kitao, Y., Yanagi, H., Stern, D.M., Ogawa, S., Regulation of tumor angiogenesis by oxygen-regulated protein 150, an inducible endoplasmic reticulum chaperone. Cancer Res. 61 (2001), 4206–4213.
-
(2001)
Cancer Res.
, vol.61
, pp. 4206-4213
-
-
Ozawa, K.1
Tsukamoto, Y.2
Hori, O.3
Kitao, Y.4
Yanagi, H.5
Stern, D.M.6
Ogawa, S.7
-
13
-
-
0026654505
-
Calcium is required for folding of newly made subunits of the asialoglycoprotein receptor within the endoplasmic reticulum
-
[13] Lodish, H.F., Kong, N., Wikstrom, L., Calcium is required for folding of newly made subunits of the asialoglycoprotein receptor within the endoplasmic reticulum. J. Biol. Chem. 267 (1992), 12753–12760.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 12753-12760
-
-
Lodish, H.F.1
Kong, N.2
Wikstrom, L.3
-
14
-
-
84995680360
-
Ablation of aldehyde reductase aggravates carbon tetrachloride-induced acute hepatic injury involving oxidative stress and endoplasmic reticulum stress
-
[14] Akihara, R., Homma, T., Lee, J., Yamada, K., Miyata, S., Fujii, J., Ablation of aldehyde reductase aggravates carbon tetrachloride-induced acute hepatic injury involving oxidative stress and endoplasmic reticulum stress. Biochem. Biophys. Res. Commun. 478 (2016), 765–771.
-
(2016)
Biochem. Biophys. Res. Commun.
, vol.478
, pp. 765-771
-
-
Akihara, R.1
Homma, T.2
Lee, J.3
Yamada, K.4
Miyata, S.5
Fujii, J.6
-
15
-
-
85009239499
-
Herpes simplex virus 1 UL41 protein suppresses the IRE1/XBP1 signal pathway of the unfolded protein response via its RNase activity
-
[15] Zhang, P., Su, C., Jiang, Z., Zheng, C., Herpes simplex virus 1 UL41 protein suppresses the IRE1/XBP1 signal pathway of the unfolded protein response via its RNase activity. J. Virol., 2016.
-
(2016)
J. Virol.
-
-
Zhang, P.1
Su, C.2
Jiang, Z.3
Zheng, C.4
-
16
-
-
22244446505
-
The mammalian unfolded protein response
-
[16] Schroder, M., Kaufman, R.J., The mammalian unfolded protein response. Annu. Rev. Biochem. 74 (2005), 739–789.
-
(2005)
Annu. Rev. Biochem.
, vol.74
, pp. 739-789
-
-
Schroder, M.1
Kaufman, R.J.2
-
17
-
-
43249109174
-
Endoplasmic reticulum stress responses
-
[17] Schroder, M., Endoplasmic reticulum stress responses. Cell. Mol. Life Sci. 65 (2008), 862–894.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 862-894
-
-
Schroder, M.1
-
18
-
-
84900312241
-
Endoplasmic reticulum stress in malignancy
-
[18] Clarke, H.J., Chambers, J.E., Liniker, E., Marciniak, S.J., Endoplasmic reticulum stress in malignancy. Cancer Cell 25 (2014), 563–573.
-
(2014)
Cancer Cell
, vol.25
, pp. 563-573
-
-
Clarke, H.J.1
Chambers, J.E.2
Liniker, E.3
Marciniak, S.J.4
-
19
-
-
84938198681
-
Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: mechanisms and targets for therapy
-
[19] Tameire, F., Verginadis, I.I., Koumenis, C., Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: mechanisms and targets for therapy. Semin. Cancer Biol. 33 (2015), 3–15.
-
(2015)
Semin. Cancer Biol.
, vol.33
, pp. 3-15
-
-
Tameire, F.1
Verginadis, I.I.2
Koumenis, C.3
-
20
-
-
84876098009
-
Stress induced apoptosis and inflammation in cancer
-
[20] Verfaillie, T., Garg, A.D., Agostinis, P., Targeting, E.R., Stress induced apoptosis and inflammation in cancer. Cancer Lett. 332 (2013), 249–264.
-
(2013)
Cancer Lett.
, vol.332
, pp. 249-264
-
-
Verfaillie, T.1
Garg, A.D.2
Agostinis, P.3
Targeting, E.R.4
-
21
-
-
84896499806
-
The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease
-
[21] Jovaisaite, V., Mouchiroud, L., Auwerx, J., The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease. J. Exp. Biol. 217 (2014), 137–143.
-
(2014)
J. Exp. Biol.
, vol.217
, pp. 137-143
-
-
Jovaisaite, V.1
Mouchiroud, L.2
Auwerx, J.3
-
22
-
-
84938207247
-
Controlling the unfolded protein response-mediated life and death decisions in cancer
-
[22] Maurel, M., McGrath, E.P., Mnich, K., Healy, S., Chevet, E., Samali, A., Controlling the unfolded protein response-mediated life and death decisions in cancer. Semin. Cancer Biol. 33 (2015), 57–66.
-
(2015)
Semin. Cancer Biol.
, vol.33
, pp. 57-66
-
-
Maurel, M.1
McGrath, E.P.2
Mnich, K.3
Healy, S.4
Chevet, E.5
Samali, A.6
-
23
-
-
79954426157
-
Signaling cell death from the endoplasmic reticulum stress response
-
[23] Shore, G.C., Papa, F.R., Oakes, S.A., Signaling cell death from the endoplasmic reticulum stress response. Curr. Opin. Cell Biol. 23 (2011), 143–149.
-
(2011)
Curr. Opin. Cell Biol.
, vol.23
, pp. 143-149
-
-
Shore, G.C.1
Papa, F.R.2
Oakes, S.A.3
-
24
-
-
77949911706
-
Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells
-
[24] Armstrong, J.L., Flockhart, R., Veal, G.J., Lovat, P.E., Redfern, C.P., Regulation of endoplasmic reticulum stress-induced cell death by ATF4 in neuroectodermal tumor cells. J. Biol. Chem. 285 (2010), 6091–6100.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6091-6100
-
-
Armstrong, J.L.1
Flockhart, R.2
Veal, G.J.3
Lovat, P.E.4
Redfern, C.P.5
-
25
-
-
78650664053
-
Endoplasmic reticulum stress-mediated apoptosis of EBV-transformed B cells by cross-linking of CD70 is dependent upon generation of reactive oxygen species and activation of p38 MAPK and JNK pathway
-
[25] Park, G.B., Kim, Y.S., Lee, H.K., Song, H., Cho, D.H., Lee, W.J., Hur, D.Y., Endoplasmic reticulum stress-mediated apoptosis of EBV-transformed B cells by cross-linking of CD70 is dependent upon generation of reactive oxygen species and activation of p38 MAPK and JNK pathway. J. Immunol. 185 (2010), 7274–7284.
-
(2010)
J. Immunol.
, vol.185
, pp. 7274-7284
-
-
Park, G.B.1
Kim, Y.S.2
Lee, H.K.3
Song, H.4
Cho, D.H.5
Lee, W.J.6
Hur, D.Y.7
-
26
-
-
58049214863
-
Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis
-
[26] Lei, X., Zhang, S., Bohrer, A., Ramanadham, S., Calcium-independent phospholipase A2 (iPLA2 beta)-mediated ceramide generation plays a key role in the cross-talk between the endoplasmic reticulum (ER) and mitochondria during ER stress-induced insulin-secreting cell apoptosis. J. Biol. Chem. 283 (2008), 34819–34832.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 34819-34832
-
-
Lei, X.1
Zhang, S.2
Bohrer, A.3
Ramanadham, S.4
-
27
-
-
34548037901
-
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
-
[27] Hoyer-Hansen, M., Jaattela, M., Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Differ. 14 (2007), 1576–1582.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1576-1582
-
-
Hoyer-Hansen, M.1
Jaattela, M.2
-
28
-
-
84975796689
-
Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis
-
[28] Chevet, E., Hetz, C., Samali, A., Endoplasmic reticulum stress-activated cell reprogramming in oncogenesis. Cancer Discov. 5 (2015), 586–597.
-
(2015)
Cancer Discov.
, vol.5
, pp. 586-597
-
-
Chevet, E.1
Hetz, C.2
Samali, A.3
-
29
-
-
84864878269
-
Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease
-
[29] Vidal, R.L., Hetz, C., Crosstalk between the UPR and autophagy pathway contributes to handling cellular stress in neurodegenerative disease. Autophagy 8 (2012), 970–972.
-
(2012)
Autophagy
, vol.8
, pp. 970-972
-
-
Vidal, R.L.1
Hetz, C.2
-
30
-
-
33749579383
-
Endoplasmic reticulum stress triggers autophagy
-
[30] Yorimitsu, T., Nair, U., Yang, Z., Klionsky, D.J., Endoplasmic reticulum stress triggers autophagy. J. Biol. Chem. 281 (2006), 30299–30304.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 30299-30304
-
-
Yorimitsu, T.1
Nair, U.2
Yang, Z.3
Klionsky, D.J.4
-
31
-
-
84988044805
-
The energetics of genome complexity
-
[31] Lane, N., Martin, W., The energetics of genome complexity. Nature 467 (2010), 929–934.
-
(2010)
Nature
, vol.467
, pp. 929-934
-
-
Lane, N.1
Martin, W.2
-
32
-
-
73349091842
-
The role of mitochondria in apoptosis
-
[32] Wang, C., Youle, R.J., The role of mitochondria in apoptosis. Annu. Rev. Genet. 43 (2009), 95–118.
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 95-118
-
-
Wang, C.1
Youle, R.J.2
-
34
-
-
84900562472
-
Mitochondrial and postmitochondrial survival signaling in cancer
-
[34] Yadav, N., Chandra, D., Mitochondrial and postmitochondrial survival signaling in cancer. Mitochondrion 16 (2014), 18–25.
-
(2014)
Mitochondrion
, vol.16
, pp. 18-25
-
-
Yadav, N.1
Chandra, D.2
-
35
-
-
34250204271
-
The machines that divide and fuse mitochondria
-
[35] Hoppins, S., Lackner, L., Nunnari, J., The machines that divide and fuse mitochondria. Annu. Rev. Biochem. 76 (2007), 751–780.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 751-780
-
-
Hoppins, S.1
Lackner, L.2
Nunnari, J.3
-
36
-
-
80054844842
-
ER tubules mark sites of mitochondrial division
-
[36] Friedman, J.R., Lackner, L.L., West, M., DiBenedetto, J.R., Nunnari, J., Voeltz, G.K., ER tubules mark sites of mitochondrial division. Science 334 (2011), 358–362.
-
(2011)
Science
, vol.334
, pp. 358-362
-
-
Friedman, J.R.1
Lackner, L.L.2
West, M.3
DiBenedetto, J.R.4
Nunnari, J.5
Voeltz, G.K.6
-
37
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
[37] Suen, D.F., Norris, K.L., Youle, R.J., Mitochondrial dynamics and apoptosis. Genes Dev. 22 (2008), 1577–1590.
-
(2008)
Genes Dev.
, vol.22
, pp. 1577-1590
-
-
Suen, D.F.1
Norris, K.L.2
Youle, R.J.3
-
38
-
-
84865547276
-
Cell Biology. Mitochondrial dynamics and apoptosis–the ER connection
-
[38] Hoppins, S., Nunnari, J., Cell Biology. Mitochondrial dynamics and apoptosis–the ER connection. Science 337 (2012), 1052–1054.
-
(2012)
Science
, vol.337
, pp. 1052-1054
-
-
Hoppins, S.1
Nunnari, J.2
-
39
-
-
34347386472
-
Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis
-
[39] Hom, J.R., Gewandter, J.S., Michael, L., Sheu, S.S., Yoon, Y., Thapsigargin induces biphasic fragmentation of mitochondria through calcium-mediated mitochondrial fission and apoptosis. J. Cell. Physiol. 212 (2007), 498–508.
-
(2007)
J. Cell. Physiol.
, vol.212
, pp. 498-508
-
-
Hom, J.R.1
Gewandter, J.S.2
Michael, L.3
Sheu, S.S.4
Yoon, Y.5
-
40
-
-
84908082447
-
Stress-responsive regulation of mitochondria through the ER unfolded protein response
-
[40] Rainbolt, T.K., Saunders, J.M., Wiseman, R.L., Stress-responsive regulation of mitochondria through the ER unfolded protein response. Trends Endocrinol. Metab. 25 (2014), 528–537.
-
(2014)
Trends Endocrinol. Metab.
, vol.25
, pp. 528-537
-
-
Rainbolt, T.K.1
Saunders, J.M.2
Wiseman, R.L.3
-
41
-
-
33750902737
-
The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control
-
[41] Gorlach, A., Klappa, P., Kietzmann, T., The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control. Antioxid. Redox Signal. 8 (2006), 1391–1418.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, pp. 1391-1418
-
-
Gorlach, A.1
Klappa, P.2
Kietzmann, T.3
-
42
-
-
84923181354
-
Molecular pathways: the PERKs and pitfalls of targeting the unfolded protein response in cancer
-
[42] Maas, N.L., Diehl, J.A., Molecular pathways: the PERKs and pitfalls of targeting the unfolded protein response in cancer. Clin. Cancer Res. 21 (2015), 675–679.
-
(2015)
Clin. Cancer Res.
, vol.21
, pp. 675-679
-
-
Maas, N.L.1
Diehl, J.A.2
-
43
-
-
77958472998
-
Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response
-
[43] Dey, S., Baird, T.D., Zhou, D., Palam, L.R., Spandau, D.F., Wek, R.C., Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response. J. Biol. Chem. 285 (2010), 33165–33174.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 33165-33174
-
-
Dey, S.1
Baird, T.D.2
Zhou, D.3
Palam, L.R.4
Spandau, D.F.5
Wek, R.C.6
-
44
-
-
84866782195
-
Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism
-
[44] Baird, T.D., Wek, R.C., Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism. Adv. Nutr. 3 (2012), 307–321.
-
(2012)
Adv. Nutr.
, vol.3
, pp. 307-321
-
-
Baird, T.D.1
Wek, R.C.2
-
45
-
-
84866783355
-
The transcription factor network associated with the amino acid response in mammalian cells
-
[45] Kilberg, M.S., Balasubramanian, M., Fu, L., Shan, J., The transcription factor network associated with the amino acid response in mammalian cells. Adv. Nutr. 3 (2012), 295–306.
-
(2012)
Adv. Nutr.
, vol.3
, pp. 295-306
-
-
Kilberg, M.S.1
Balasubramanian, M.2
Fu, L.3
Shan, J.4
-
46
-
-
0141621215
-
Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements
-
[46] Luo, S., Baumeister, P., Yang, S., Abcouwer, S.F., Lee, A.S., Induction of Grp78/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF/CRE site independent of the endoplasmic reticulum stress elements. J. Biol. Chem. 278 (2003), 37375–37385.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37375-37385
-
-
Luo, S.1
Baumeister, P.2
Yang, S.3
Abcouwer, S.F.4
Lee, A.S.5
-
47
-
-
33745022822
-
Cadmium induces the expression of Grp78, an endoplasmic reticulum molecular chaperone, in LLC-PK1 renal epithelial cells
-
[47] Liu, F., Inageda, K., Nishitai, G., Matsuoka, M., Cadmium induces the expression of Grp78, an endoplasmic reticulum molecular chaperone, in LLC-PK1 renal epithelial cells. Environ. Health Perspect. 114 (2006), 859–864.
-
(2006)
Environ. Health Perspect.
, vol.114
, pp. 859-864
-
-
Liu, F.1
Inageda, K.2
Nishitai, G.3
Matsuoka, M.4
-
48
-
-
43549125786
-
ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo
-
[48] Lange, P.S., Chavez, J.C., Pinto, J.T., Coppola, G., Sun, C.W., Townes, T.M., Geschwind, D.H., Ratan, R.R., ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo. J. Exp. Med. 205 (2008), 1227–1242.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1227-1242
-
-
Lange, P.S.1
Chavez, J.C.2
Pinto, J.T.3
Coppola, G.4
Sun, C.W.5
Townes, T.M.6
Geschwind, D.H.7
Ratan, R.R.8
-
49
-
-
84953327405
-
KDM4C and ATF4 cooperate in transcriptional control of amino acid metabolism
-
[49] Zhao, E., Ding, J., Xia, Y., Liu, M., Ye, B., Choi, J.H., Yan, C., Dong, Z., Huang, S., Zha, Y., Yang, L., Cui, H., Ding, H.F., KDM4C and ATF4 cooperate in transcriptional control of amino acid metabolism. Cell Rep. 14 (2016), 506–519.
-
(2016)
Cell Rep.
, vol.14
, pp. 506-519
-
-
Zhao, E.1
Ding, J.2
Xia, Y.3
Liu, M.4
Ye, B.5
Choi, J.H.6
Yan, C.7
Dong, Z.8
Huang, S.9
Zha, Y.10
Yang, L.11
Cui, H.12
Ding, H.F.13
-
50
-
-
84887620237
-
ER stress-induced cell death mechanisms
-
[50] Sano, R., Reed, J.C., ER stress-induced cell death mechanisms. Biochim. Biophys. Acta 1833 (2013), 3460–3470.
-
(2013)
Biochim. Biophys. Acta
, vol.1833
, pp. 3460-3470
-
-
Sano, R.1
Reed, J.C.2
-
51
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
[51] Kobayashi, A., Kang, M.I., Okawa, H., Ohtsuji, M., Zenke, Y., Chiba, T., Igarashi, K., Yamamoto, M., Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol. Cell. Biol. 24 (2004), 7130–7139.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
Kang, M.I.2
Okawa, H.3
Ohtsuji, M.4
Zenke, Y.5
Chiba, T.6
Igarashi, K.7
Yamamoto, M.8
-
52
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
[52] Cullinan, S.B., Zhang, D., Hannink, M., Arvisais, E., Kaufman, R.J., Diehl, J.A., Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol. Cell. Biol. 23 (2003), 7198–7209.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
53
-
-
33846013251
-
Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa
-
[53] Fribley, A.M., Evenchik, B., Zeng, Q., Park, B.K., Guan, J.Y., Zhang, H., Hale, T.J., Soengas, M.S., Kaufman, R.J., Wang, C.Y., Proteasome inhibitor PS-341 induces apoptosis in cisplatin-resistant squamous cell carcinoma cells by induction of Noxa. J. Biol. Chem. 281 (2006), 31440–31447.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 31440-31447
-
-
Fribley, A.M.1
Evenchik, B.2
Zeng, Q.3
Park, B.K.4
Guan, J.Y.5
Zhang, H.6
Hale, T.J.7
Soengas, M.S.8
Kaufman, R.J.9
Wang, C.Y.10
-
54
-
-
4444311881
-
Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity
-
[54] Mimnaugh, E.G., Xu, W., Vos, M., Yuan, X., Isaacs, J.S., Bisht, K.S., Gius, D., Neckers, L., Simultaneous inhibition of hsp 90 and the proteasome promotes protein ubiquitination, causes endoplasmic reticulum-derived cytosolic vacuolization, and enhances antitumor activity. Mol. Cancer Ther. 3 (2004), 551–566.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 551-566
-
-
Mimnaugh, E.G.1
Xu, W.2
Vos, M.3
Yuan, X.4
Isaacs, J.S.5
Bisht, K.S.6
Gius, D.7
Neckers, L.8
-
55
-
-
29244454269
-
Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis
-
[55] Nawrocki, S.T., Carew, J.S., Pino, M.S., Highshaw, R.A., Dunner, K. Jr., Huang, P., Abbruzzese, J.L., McConkey, D.J., Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res. 65 (2005), 11658–11666.
-
(2005)
Cancer Res.
, vol.65
, pp. 11658-11666
-
-
Nawrocki, S.T.1
Carew, J.S.2
Pino, M.S.3
Highshaw, R.A.4
Dunner, K.5
Huang, P.6
Abbruzzese, J.L.7
McConkey, D.J.8
-
56
-
-
84906273649
-
The unfolded protein response as a target for cancer therapy
-
[56] Nagelkerke, A., Bussink, J., Sweep, F.C., Span, P.N., The unfolded protein response as a target for cancer therapy. Biochim. Biophys. Acta 1846 (2014), 277–284.
-
(2014)
Biochim. Biophys. Acta
, vol.1846
, pp. 277-284
-
-
Nagelkerke, A.1
Bussink, J.2
Sweep, F.C.3
Span, P.N.4
-
57
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
[57] Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., Yamamoto, M., Nabeshima, Y., An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem. Biophys. Res. Commun. 236 (1997), 313–322.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
Chiba, T.2
Takahashi, S.3
Ishii, T.4
Igarashi, K.5
Katoh, Y.6
Oyake, T.7
Hayashi, N.8
Satoh, K.9
Hatayama, I.10
Yamamoto, M.11
Nabeshima, Y.12
-
58
-
-
33847050801
-
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
-
[58] Kensler, T.W., Wakabayashi, N., Biswal, S., Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 47 (2007), 89–116.
-
(2007)
Annu. Rev. Pharmacol. Toxicol.
, vol.47
, pp. 89-116
-
-
Kensler, T.W.1
Wakabayashi, N.2
Biswal, S.3
-
59
-
-
84858964113
-
Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis
-
[59] Niture, S.K., Jaiswal, A.K., Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis. J. Biol. Chem. 287 (2012), 9873–9886.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 9873-9886
-
-
Niture, S.K.1
Jaiswal, A.K.2
-
60
-
-
84873732409
-
Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance
-
[60] Niture, S.K., Jaiswal, A.K., Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance. Free Radic. Biol. Med. 57 (2013), 119–131.
-
(2013)
Free Radic. Biol. Med.
, vol.57
, pp. 119-131
-
-
Niture, S.K.1
Jaiswal, A.K.2
-
61
-
-
0028206341
-
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
-
[61] Yin, X.M., Oltvai, Z.N., Korsmeyer, S.J., BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369 (1994), 321–323.
-
(1994)
Nature
, vol.369
, pp. 321-323
-
-
Yin, X.M.1
Oltvai, Z.N.2
Korsmeyer, S.J.3
-
62
-
-
9844257587
-
Inhibition of Bax channel-forming activity by Bcl-2
-
[62] Antonsson, B., Conti, F., Ciavatta, A., Montessuit, S., Lewis, S., Martinou, I., Bernasconi, L., Bernard, A., Mermod, J.J., Mazzei, G., Maundrell, K., Gambale, F., Sadoul, R., Martinou, J.C., Inhibition of Bax channel-forming activity by Bcl-2. Science 277 (1997), 370–372.
-
(1997)
Science
, vol.277
, pp. 370-372
-
-
Antonsson, B.1
Conti, F.2
Ciavatta, A.3
Montessuit, S.4
Lewis, S.5
Martinou, I.6
Bernasconi, L.7
Bernard, A.8
Mermod, J.J.9
Mazzei, G.10
Maundrell, K.11
Gambale, F.12
Sadoul, R.13
Martinou, J.C.14
-
63
-
-
0033593230
-
Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL
-
[63] Finucane, D.M., Bossy-Wetzel, E., Waterhouse, N.J., Cotter, T.G., Green, D.R., Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhibitable by Bcl-xL. J. Biol. Chem. 274 (1999), 2225–2233.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2225-2233
-
-
Finucane, D.M.1
Bossy-Wetzel, E.2
Waterhouse, N.J.3
Cotter, T.G.4
Green, D.R.5
-
64
-
-
0032515874
-
Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
-
[64] Hu, Y., Benedict, M.A., Wu, D., Inohara, N., Nunez, G., Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation. Proc. Natl. Acad. Sci. U. S. A. 95 (1998), 4386–4391.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 4386-4391
-
-
Hu, Y.1
Benedict, M.A.2
Wu, D.3
Inohara, N.4
Nunez, G.5
-
65
-
-
33646373219
-
Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53
-
[65] Li, J., Lee, B., Lee, A.S., Endoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53. J. Biol. Chem. 281 (2006), 7260–7270.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 7260-7270
-
-
Li, J.1
Lee, B.2
Lee, A.S.3
-
66
-
-
84856111924
-
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
-
[66] Hetz, C., The unfolded protein response: controlling cell fate decisions under ER stress and beyond. Nat. Rev. Mol. Cell Biol. 13 (2012), 89–102.
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
67
-
-
67349282556
-
Preventing oxidative stress: a new role for XBP1
-
[67] Liu, Y., Adachi, M., Zhao, S., Hareyama, M., Koong, A.C., Luo, D., Rando, T.A., Imai, K., Shinomura, Y., Preventing oxidative stress: a new role for XBP1. Cell Death Differ. 16 (2009), 847–857.
-
(2009)
Cell Death Differ.
, vol.16
, pp. 847-857
-
-
Liu, Y.1
Adachi, M.2
Zhao, S.3
Hareyama, M.4
Koong, A.C.5
Luo, D.6
Rando, T.A.7
Imai, K.8
Shinomura, Y.9
-
68
-
-
84922211982
-
Phosphoregulation of Ire1 RNase splicing activity
-
[68] Prischi, F., Nowak, P.R., Carrara, M., Ali, M.M., Phosphoregulation of Ire1 RNase splicing activity. Nat. Commun., 5, 2014, 3554.
-
(2014)
Nat. Commun.
, vol.5
, pp. 3554
-
-
Prischi, F.1
Nowak, P.R.2
Carrara, M.3
Ali, M.M.4
-
69
-
-
34548172495
-
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1
-
[69] Yamamoto, K., Sato, T., Matsui, T., Sato, M., Okada, T., Yoshida, H., Harada, A., Mori, K., Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev. Cell 13 (2007), 365–376.
-
(2007)
Dev. Cell
, vol.13
, pp. 365-376
-
-
Yamamoto, K.1
Sato, T.2
Matsui, T.3
Sato, M.4
Okada, T.5
Yoshida, H.6
Harada, A.7
Mori, K.8
-
70
-
-
67650000500
-
ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum
-
[70] Bommiasamy, H., Back, S.H., Fagone, P., Lee, K., Meshinchi, S., Vink, E., Sriburi, R., Frank, M., Jackowski, S., Kaufman, R.J., Brewer, J.W., ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum. J. Cell Sci. 122 (2009), 1626–1636.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 1626-1636
-
-
Bommiasamy, H.1
Back, S.H.2
Fagone, P.3
Lee, K.4
Meshinchi, S.5
Vink, E.6
Sriburi, R.7
Frank, M.8
Jackowski, S.9
Kaufman, R.J.10
Brewer, J.W.11
-
71
-
-
84877578475
-
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
-
[71] Han, J., Back, S.H., Hur, J., Lin, Y.H., Gildersleeve, R., Shan, J., Yuan, C.L., Krokowski, D., Wang, S., Hatzoglou, M., Kilberg, M.S., Sartor, M.A., Kaufman, R.J., ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. Nat. Cell Biol. 15 (2013), 481–490.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 481-490
-
-
Han, J.1
Back, S.H.2
Hur, J.3
Lin, Y.H.4
Gildersleeve, R.5
Shan, J.6
Yuan, C.L.7
Krokowski, D.8
Wang, S.9
Hatzoglou, M.10
Kilberg, M.S.11
Sartor, M.A.12
Kaufman, R.J.13
-
72
-
-
0036314984
-
Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
-
[72] Ma, Y., Brewer, J.W., Diehl, J.A., Hendershot, L.M., Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J. Mol. Biol. 318 (2002), 1351–1365.
-
(2002)
J. Mol. Biol.
, vol.318
, pp. 1351-1365
-
-
Ma, Y.1
Brewer, J.W.2
Diehl, J.A.3
Hendershot, L.M.4
-
73
-
-
33751069967
-
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
-
[73] Rutkowski, D.T., Arnold, S.M., Miller, C.N., Wu, J., Li, J., Gunnison, K.M., Mori, K., Sadighi Akha, A.A., Raden, D., Kaufman, R.J., Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol., 4, 2006, e374.
-
(2006)
PLoS Biol.
, vol.4
, pp. e374
-
-
Rutkowski, D.T.1
Arnold, S.M.2
Miller, C.N.3
Wu, J.4
Li, J.5
Gunnison, K.M.6
Mori, K.7
Sadighi Akha, A.A.8
Raden, D.9
Kaufman, R.J.10
-
74
-
-
1242272070
-
Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation
-
[74] Averous, J., Bruhat, A., Jousse, C., Carraro, V., Thiel, G., Fafournoux, P., Induction of CHOP expression by amino acid limitation requires both ATF4 expression and ATF2 phosphorylation. J. Biol. Chem. 279 (2004), 5288–5297.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 5288-5297
-
-
Averous, J.1
Bruhat, A.2
Jousse, C.3
Carraro, V.4
Thiel, G.5
Fafournoux, P.6
-
75
-
-
58449084895
-
Divergent effects of PERK and IRE1 signaling on cell viability
-
[75] Lin, J.H., Li, H., Zhang, Y., Ron, D., Walter, P., Divergent effects of PERK and IRE1 signaling on cell viability. PLoS One, 4, 2009, e4170.
-
(2009)
PLoS One
, vol.4
, pp. e4170
-
-
Lin, J.H.1
Li, H.2
Zhang, Y.3
Ron, D.4
Walter, P.5
-
76
-
-
84976444942
-
The dual roles of NRF2 in cancer
-
[76] Menegon, S., Columbano, A., Giordano, S., The dual roles of NRF2 in cancer. Trends Mol. Med. 22 (2016), 578–593.
-
(2016)
Trends Mol. Med.
, vol.22
, pp. 578-593
-
-
Menegon, S.1
Columbano, A.2
Giordano, S.3
-
77
-
-
55849096988
-
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
-
[77] Song, B., Scheuner, D., Ron, D., Pennathur, S., Kaufman, R.J., Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J. Clin. Invest. 118 (2008), 3378–3389.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3378-3389
-
-
Song, B.1
Scheuner, D.2
Ron, D.3
Pennathur, S.4
Kaufman, R.J.5
-
78
-
-
66149128392
-
Bcl-2 family on guard at the ER
-
[78] Szegezdi, E., Macdonald, D.C., Ni Chonghaile, T., Gupta, S., Samali, A., Bcl-2 family on guard at the ER. Am. J. Phys. Cell Physiol. 296 (2009), C941–C953.
-
(2009)
Am. J. Phys. Cell Physiol.
, vol.296
, pp. C941-C953
-
-
Szegezdi, E.1
Macdonald, D.C.2
Ni Chonghaile, T.3
Gupta, S.4
Samali, A.5
-
79
-
-
17644371025
-
BAK control multiple initiator caspases
-
[79] Ruiz-Vela, A., Opferman, J.T., Cheng, E.H., Korsmeyer, S.J., Proapoptotic, B.A.X., BAK control multiple initiator caspases. EMBO Rep. 6 (2005), 379–385.
-
(2005)
EMBO Rep.
, vol.6
, pp. 379-385
-
-
Ruiz-Vela, A.1
Opferman, J.T.2
Cheng, E.H.3
Korsmeyer, S.J.4
Proapoptotic, B.A.X.5
-
80
-
-
33947394480
-
Bax and the mitochondrial permeability transition cooperate in the release of cytochrome c during endoplasmic reticulum-stress-induced apoptosis
-
[80] Zhang, D., Armstrong, J.S., Bax and the mitochondrial permeability transition cooperate in the release of cytochrome c during endoplasmic reticulum-stress-induced apoptosis. Cell Death Differ. 14 (2007), 703–715.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 703-715
-
-
Zhang, D.1
Armstrong, J.S.2
-
81
-
-
84905170020
-
New insights into the roles of CHOP-induced apoptosis in ER stress
-
[81] Li, Y., Guo, Y., Tang, J., Jiang, J., Chen, Z., New insights into the roles of CHOP-induced apoptosis in ER stress. Acta Biochim. Biophys. Sin. 46 (2014), 629–640.
-
(2014)
Acta Biochim. Biophys. Sin.
, vol.46
, pp. 629-640
-
-
Li, Y.1
Guo, Y.2
Tang, J.3
Jiang, J.4
Chen, Z.5
-
82
-
-
84948428212
-
CCAAT-enhancer-binding protein homologous protein deficiency attenuates oxidative stress and renal ischemia-reperfusion injury
-
[82] Chen, B.L., Sheu, M.L., Tsai, K.S., Lan, K.C., Guan, S.S., Wu, C.T., Chen, L.P., Hung, K.Y., Huang, J.W., Chiang, C.K., Liu, S.H., CCAAT-enhancer-binding protein homologous protein deficiency attenuates oxidative stress and renal ischemia-reperfusion injury. Antioxid. Redox Signal. 23 (2015), 1233–1245.
-
(2015)
Antioxid. Redox Signal.
, vol.23
, pp. 1233-1245
-
-
Chen, B.L.1
Sheu, M.L.2
Tsai, K.S.3
Lan, K.C.4
Guan, S.S.5
Wu, C.T.6
Chen, L.P.7
Hung, K.Y.8
Huang, J.W.9
Chiang, C.K.10
Liu, S.H.11
-
83
-
-
77956288847
-
Activation of PERK signaling attenuates Abeta-mediated ER stress
-
[83] Lee, D.Y., Lee, K.S., Lee, H.J., Kim do, H., Noh, Y.H., Yu, K., Jung, H.Y., Lee, S.H., Lee, J.Y., Youn, Y.C., Jeong, Y., Kim, D.K., Lee, W.B., Kim, S.S., Activation of PERK signaling attenuates Abeta-mediated ER stress. PLoS One, 5, 2010, e10489.
-
(2010)
PLoS One
, vol.5
, pp. e10489
-
-
Lee, D.Y.1
Lee, K.S.2
Lee, H.J.3
Kim do, H.4
Noh, Y.H.5
Yu, K.6
Jung, H.Y.7
Lee, S.H.8
Lee, J.Y.9
Youn, Y.C.10
Jeong, Y.11
Kim, D.K.12
Lee, W.B.13
Kim, S.S.14
-
84
-
-
79956220325
-
Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum
-
[84] Takemoto, K., Miyata, S., Takamura, H., Katayama, T., Tohyama, M., Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum. Neurochem. Int. 58 (2011), 880–887.
-
(2011)
Neurochem. Int.
, vol.58
, pp. 880-887
-
-
Takemoto, K.1
Miyata, S.2
Takamura, H.3
Katayama, T.4
Tohyama, M.5
-
85
-
-
84862808855
-
Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31
-
[85] Heath-Engel, H., Wang, B., Shore, G., Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31. Biochim. Biophys. Acta 1823 (2012), 335–347.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 335-347
-
-
Heath-Engel, H.1
Wang, B.2
Shore, G.3
-
86
-
-
35948946873
-
Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells
-
[86] Nieto-Miguel, T., Fonteriz, R.I., Vay, L., Gajate, C., Lopez-Hernandez, S., Mollinedo, F., Endoplasmic reticulum stress in the proapoptotic action of edelfosine in solid tumor cells. Cancer Res. 67 (2007), 10368–10378.
-
(2007)
Cancer Res.
, vol.67
, pp. 10368-10378
-
-
Nieto-Miguel, T.1
Fonteriz, R.I.2
Vay, L.3
Gajate, C.4
Lopez-Hernandez, S.5
Mollinedo, F.6
-
87
-
-
62049085194
-
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
-
[87] Panaretakis, T., Kepp, O., Brockmeier, U., Tesniere, A., Bjorklund, A.C., Chapman, D.C., Durchschlag, M., Joza, N., Pierron, G., van Endert, P., Yuan, J., Zitvogel, L., Madeo, F., Williams, D.B., Kroemer, G., Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J. 28 (2009), 578–590.
-
(2009)
EMBO J.
, vol.28
, pp. 578-590
-
-
Panaretakis, T.1
Kepp, O.2
Brockmeier, U.3
Tesniere, A.4
Bjorklund, A.C.5
Chapman, D.C.6
Durchschlag, M.7
Joza, N.8
Pierron, G.9
van Endert, P.10
Yuan, J.11
Zitvogel, L.12
Madeo, F.13
Williams, D.B.14
Kroemer, G.15
-
88
-
-
72549095406
-
Regulation mechanisms and signaling pathways of autophagy
-
[88] He, C., Klionsky, D.J., Regulation mechanisms and signaling pathways of autophagy. Annu. Rev. Genet. 43 (2009), 67–93.
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 67-93
-
-
He, C.1
Klionsky, D.J.2
-
89
-
-
33846211417
-
ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation
-
[89] Kouroku, Y., Fujita, E., Tanida, I., Ueno, T., Isoai, A., Kumagai, H., Ogawa, S., Kaufman, R.J., Kominami, E., Momoi, T., ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. Cell Death Differ. 14 (2007), 230–239.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 230-239
-
-
Kouroku, Y.1
Fujita, E.2
Tanida, I.3
Ueno, T.4
Isoai, A.5
Kumagai, H.6
Ogawa, S.7
Kaufman, R.J.8
Kominami, E.9
Momoi, T.10
-
90
-
-
33846189759
-
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2
-
[90] Hoyer-Hansen, M., Bastholm, L., Szyniarowski, P., Campanella, M., Szabadkai, G., Farkas, T., Bianchi, K., Fehrenbacher, N., Elling, F., Rizzuto, R., Mathiasen, I.S., Jaattela, M., Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. Mol. Cell 25 (2007), 193–205.
-
(2007)
Mol. Cell
, vol.25
, pp. 193-205
-
-
Hoyer-Hansen, M.1
Bastholm, L.2
Szyniarowski, P.3
Campanella, M.4
Szabadkai, G.5
Farkas, T.6
Bianchi, K.7
Fehrenbacher, N.8
Elling, F.9
Rizzuto, R.10
Mathiasen, I.S.11
Jaattela, M.12
-
91
-
-
50249187551
-
Regulation of ER stress-induced macroautophagy by protein kinase C
-
[91] Sakaki, K., Kaufman, R.J., Regulation of ER stress-induced macroautophagy by protein kinase C. Autophagy 4 (2008), 841–843.
-
(2008)
Autophagy
, vol.4
, pp. 841-843
-
-
Sakaki, K.1
Kaufman, R.J.2
-
92
-
-
56349138968
-
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death
-
[92] Gozuacik, D., Bialik, S., Raveh, T., Mitou, G., Shohat, G., Sabanay, H., Mizushima, N., Yoshimori, T., Kimchi, A., DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death Differ. 15 (2008), 1875–1886.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 1875-1886
-
-
Gozuacik, D.1
Bialik, S.2
Raveh, T.3
Mitou, G.4
Shohat, G.5
Sabanay, H.6
Mizushima, N.7
Yoshimori, T.8
Kimchi, A.9
-
93
-
-
77955947900
-
Linking ER stress to autophagy: potential implications for cancer therapy
-
[93] Verfaillie, T., Salazar, M., Velasco, G., Agostinis, P., Linking ER stress to autophagy: potential implications for cancer therapy. Int. J. Cell Biol., 2010, 2010, 930509.
-
(2010)
Int. J. Cell Biol.
, vol.2010
, pp. 930509
-
-
Verfaillie, T.1
Salazar, M.2
Velasco, G.3
Agostinis, P.4
-
94
-
-
34247380330
-
Regulation of autophagy by the inositol trisphosphate receptor
-
[94] Criollo, A., Maiuri, M.C., Tasdemir, E., Vitale, I., Fiebig, A.A., Andrews, D., Molgo, J., Diaz, J., Lavandero, S., Harper, F., Pierron, G., di Stefano, D., Rizzuto, R., Szabadkai, G., Kroemer, G., Regulation of autophagy by the inositol trisphosphate receptor. Cell Death Differ. 14 (2007), 1029–1039.
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1029-1039
-
-
Criollo, A.1
Maiuri, M.C.2
Tasdemir, E.3
Vitale, I.4
Fiebig, A.A.5
Andrews, D.6
Molgo, J.7
Diaz, J.8
Lavandero, S.9
Harper, F.10
Pierron, G.11
di Stefano, D.12
Rizzuto, R.13
Szabadkai, G.14
Kroemer, G.15
-
95
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
[95] Salazar, M., Carracedo, A., Salanueva, I.J., Hernandez-Tiedra, S., Lorente, M., Egia, A., Vazquez, P., Blazquez, C., Torres, S., Garcia, S., Nowak, J., Fimia, G.M., Piacentini, M., Cecconi, F., Pandolfi, P.P., Gonzalez-Feria, L., Iovanna, J.L., Guzman, M., Boya, P., Velasco, G., Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. J. Clin. Invest. 119 (2009), 1359–1372.
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernandez-Tiedra, S.4
Lorente, M.5
Egia, A.6
Vazquez, P.7
Blazquez, C.8
Torres, S.9
Garcia, S.10
Nowak, J.11
Fimia, G.M.12
Piacentini, M.13
Cecconi, F.14
Pandolfi, P.P.15
Gonzalez-Feria, L.16
Iovanna, J.L.17
Guzman, M.18
Boya, P.19
Velasco, G.20
more..
-
96
-
-
33947497050
-
Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival
-
[96] Ding, W.X., Ni, H.M., Gao, W., Hou, Y.F., Melan, M.A., Chen, X., Stolz, D.B., Shao, Z.M., Yin, X.M., Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival. J. Biol. Chem. 282 (2007), 4702–4710.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 4702-4710
-
-
Ding, W.X.1
Ni, H.M.2
Gao, W.3
Hou, Y.F.4
Melan, M.A.5
Chen, X.6
Stolz, D.B.7
Shao, Z.M.8
Yin, X.M.9
-
97
-
-
34250758642
-
ER stress triggers apoptosis by activating BH3-only protein Bim
-
[97] Puthalakath, H., O'Reilly, L.A., Gunn, P., Lee, L., Kelly, P.N., Huntington, N.D., Hughes, P.D., Michalak, E.M., McKimm-Breschkin, J., Motoyama, N., Gotoh, T., Akira, S., Bouillet, P., Strasser, A., ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 129 (2007), 1337–1349.
-
(2007)
Cell
, vol.129
, pp. 1337-1349
-
-
Puthalakath, H.1
O'Reilly, L.A.2
Gunn, P.3
Lee, L.4
Kelly, P.N.5
Huntington, N.D.6
Hughes, P.D.7
Michalak, E.M.8
McKimm-Breschkin, J.9
Motoyama, N.10
Gotoh, T.11
Akira, S.12
Bouillet, P.13
Strasser, A.14
-
98
-
-
0035144493
-
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
-
[98] McCullough, K.D., Martindale, J.L., Klotz, L.O., Aw, T.Y., Holbrook, N.J., Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol. Cell. Biol. 21 (2001), 1249–1259.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1249-1259
-
-
McCullough, K.D.1
Martindale, J.L.2
Klotz, L.O.3
Aw, T.Y.4
Holbrook, N.J.5
-
99
-
-
33748789479
-
Mediators of endoplasmic reticulum stress-induced apoptosis
-
[99] Szegezdi, E., Logue, S.E., Gorman, A.M., Samali, A., Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep. 7 (2006), 880–885.
-
(2006)
EMBO Rep.
, vol.7
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
100
-
-
84926024405
-
ER stress and ER stress-mediated apoptosis are involved in manganese-induced neurotoxicity in the rat striatum in vivo
-
[100] Wang, T., Li, X., Yang, D., Zhang, H., Zhao, P., Fu, J., Yao, B., Zhou, Z., ER stress and ER stress-mediated apoptosis are involved in manganese-induced neurotoxicity in the rat striatum in vivo. Neurotoxicology 48 (2015), 109–119.
-
(2015)
Neurotoxicology
, vol.48
, pp. 109-119
-
-
Wang, T.1
Li, X.2
Yang, D.3
Zhang, H.4
Zhao, P.5
Fu, J.6
Yao, B.7
Zhou, Z.8
-
101
-
-
84964294550
-
CHOP contributes to, but is not the only mediator of, IAPP induced beta-cell apoptosis
-
[101] Gurlo, T., Rivera, J.F., Butler, A.E., Cory, M., Hoang, J., Costes, S., Butler, P.C., CHOP contributes to, but is not the only mediator of, IAPP induced beta-cell apoptosis. Mol. Endocrinol. 30 (2016), 446–454.
-
(2016)
Mol. Endocrinol.
, vol.30
, pp. 446-454
-
-
Gurlo, T.1
Rivera, J.F.2
Butler, A.E.3
Cory, M.4
Hoang, J.5
Costes, S.6
Butler, P.C.7
-
102
-
-
60549109872
-
ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells
-
[102] Wang, Q., Mora-Jensen, H., Weniger, M.A., Perez-Galan, P., Wolford, C., Hai, T., Ron, D., Chen, W., Trenkle, W., Wiestner, A., Ye, Y., ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 2200–2205.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 2200-2205
-
-
Wang, Q.1
Mora-Jensen, H.2
Weniger, M.A.3
Perez-Galan, P.4
Wolford, C.5
Hai, T.6
Ron, D.7
Chen, W.8
Trenkle, W.9
Wiestner, A.10
Ye, Y.11
-
103
-
-
84976502335
-
Modulation of oxidative stress and subsequent induction of apoptosis and endoplasmic reticulum stress allows citral to decrease cancer cell proliferation
-
[103] Kapur, A., Felder, M., Fass, L., Kaur, J., Czarnecki, A., Rathi, K., Zeng, S., Osowski, K.K., Howell, C., Xiong, M.P., Whelan, R.J., Patankar, M.S., Modulation of oxidative stress and subsequent induction of apoptosis and endoplasmic reticulum stress allows citral to decrease cancer cell proliferation. Sci. Rep., 6, 2016, 27530.
-
(2016)
Sci. Rep.
, vol.6
, pp. 27530
-
-
Kapur, A.1
Felder, M.2
Fass, L.3
Kaur, J.4
Czarnecki, A.5
Rathi, K.6
Zeng, S.7
Osowski, K.K.8
Howell, C.9
Xiong, M.P.10
Whelan, R.J.11
Patankar, M.S.12
-
104
-
-
84925397246
-
Downregulation of E2F1 during ER stress is required to induce apoptosis
-
[104] Pagliarini, V., Giglio, P., Bernardoni, P., De Zio, D., Fimia, G.M., Piacentini, M., Corazzari, M., Downregulation of E2F1 during ER stress is required to induce apoptosis. J. Cell Sci. 128 (2015), 1166–1179.
-
(2015)
J. Cell Sci.
, vol.128
, pp. 1166-1179
-
-
Pagliarini, V.1
Giglio, P.2
Bernardoni, P.3
De Zio, D.4
Fimia, G.M.5
Piacentini, M.6
Corazzari, M.7
-
105
-
-
67649547153
-
Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak
-
[105] Klee, M., Pallauf, K., Alcala, S., Fleischer, A., Pimentel-Muinos, F.X., Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak. EMBO J. 28 (2009), 1757–1768.
-
(2009)
EMBO J.
, vol.28
, pp. 1757-1768
-
-
Klee, M.1
Pallauf, K.2
Alcala, S.3
Fleischer, A.4
Pimentel-Muinos, F.X.5
-
106
-
-
77950861972
-
Involvement of JNK in the regulation of autophagic cell death
-
[106] Shimizu, S., Konishi, A., Nishida, Y., Mizuta, T., Nishina, H., Yamamoto, A., Tsujimoto, Y., Involvement of JNK in the regulation of autophagic cell death. Oncogene 29 (2010), 2070–2082.
-
(2010)
Oncogene
, vol.29
, pp. 2070-2082
-
-
Shimizu, S.1
Konishi, A.2
Nishida, Y.3
Mizuta, T.4
Nishina, H.5
Yamamoto, A.6
Tsujimoto, Y.7
-
107
-
-
84883387793
-
Targeting the unfolded protein response in disease
-
[107] Hetz, C., Chevet, E., Harding, H.P., Targeting the unfolded protein response in disease. Nat. Rev. Drug Discov. 12 (2013), 703–719.
-
(2013)
Nat. Rev. Drug Discov.
, vol.12
, pp. 703-719
-
-
Hetz, C.1
Chevet, E.2
Harding, H.P.3
-
108
-
-
70349930116
-
Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion
-
[108] DeVay, R.M., Dominguez-Ramirez, L., Lackner, L.L., Hoppins, S., Stahlberg, H., Nunnari, J., Coassembly of Mgm1 isoforms requires cardiolipin and mediates mitochondrial inner membrane fusion. J. Cell Biol. 186 (2009), 793–803.
-
(2009)
J. Cell Biol.
, vol.186
, pp. 793-803
-
-
DeVay, R.M.1
Dominguez-Ramirez, L.2
Lackner, L.L.3
Hoppins, S.4
Stahlberg, H.5
Nunnari, J.6
-
109
-
-
84865544952
-
Mitochondrial fission, fusion, and stress
-
[109] Youle, R.J., van der Bliek, A.M., Mitochondrial fission, fusion, and stress. Science 337 (2012), 1062–1065.
-
(2012)
Science
, vol.337
, pp. 1062-1065
-
-
Youle, R.J.1
van der Bliek, A.M.2
-
110
-
-
49349112331
-
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization
-
[110] Yamaguchi, R., Lartigue, L., Perkins, G., Scott, R.T., Dixit, A., Kushnareva, Y., Kuwana, T., Ellisman, M.H., Newmeyer, D.D., Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization. Mol. Cell 31 (2008), 557–569.
-
(2008)
Mol. Cell
, vol.31
, pp. 557-569
-
-
Yamaguchi, R.1
Lartigue, L.2
Perkins, G.3
Scott, R.T.4
Dixit, A.5
Kushnareva, Y.6
Kuwana, T.7
Ellisman, M.H.8
Newmeyer, D.D.9
-
111
-
-
67649389595
-
Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1
-
[111] Yamaguchi, R., Perkins, G., Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1. Biochim. Biophys. Acta 1787 (2009), 963–972.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 963-972
-
-
Yamaguchi, R.1
Perkins, G.2
-
112
-
-
0037164813
-
Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis
-
[112] Karbowski, M., Lee, Y.J., Gaume, B., Jeong, S.Y., Frank, S., Nechushtan, A., Santel, A., Fuller, M., Smith, C.L., Youle, R.J., Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J. Cell Biol. 159 (2002), 931–938.
-
(2002)
J. Cell Biol.
, vol.159
, pp. 931-938
-
-
Karbowski, M.1
Lee, Y.J.2
Gaume, B.3
Jeong, S.Y.4
Frank, S.5
Nechushtan, A.6
Santel, A.7
Fuller, M.8
Smith, C.L.9
Youle, R.J.10
-
113
-
-
84941254697
-
Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis
-
[113] Wang, P., Wang, P., Liu, B., Zhao, J., Pang, Q., Agrawal, S.G., Jia, L., Liu, F.T., Dynamin-related protein Drp1 is required for Bax translocation to mitochondria in response to irradiation-induced apoptosis. Oncotarget 6 (2015), 22598–22612.
-
(2015)
Oncotarget
, vol.6
, pp. 22598-22612
-
-
Wang, P.1
Wang, P.2
Liu, B.3
Zhao, J.4
Pang, Q.5
Agrawal, S.G.6
Jia, L.7
Liu, F.T.8
-
114
-
-
84958604397
-
Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis
-
[114] Grosse, L., Wurm, C.A., Bruser, C., Neumann, D., Jans, D.C., Jakobs, S., Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis. EMBO J. 35 (2016), 402–413.
-
(2016)
EMBO J.
, vol.35
, pp. 402-413
-
-
Grosse, L.1
Wurm, C.A.2
Bruser, C.3
Neumann, D.4
Jans, D.C.5
Jakobs, S.6
-
115
-
-
84973449037
-
Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation-induced apoptosis
-
[115] Zhang, Z., Liu, L., Wu, S., Xing, D., Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation-induced apoptosis. FASEB J. 30 (2016), 466–476.
-
(2016)
FASEB J.
, vol.30
, pp. 466-476
-
-
Zhang, Z.1
Liu, L.2
Wu, S.3
Xing, D.4
-
116
-
-
84961900214
-
DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress
-
[116] Oettinghaus, B., D'Alonzo, D., Barbieri, E., Restelli, L.M., Savoia, C., Licci, M., Tolnay, M., Frank, S., Scorrano, L., DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress. Biochim. Biophys. Acta 1857 (2016), 1267–1276.
-
(2016)
Biochim. Biophys. Acta
, vol.1857
, pp. 1267-1276
-
-
Oettinghaus, B.1
D'Alonzo, D.2
Barbieri, E.3
Restelli, L.M.4
Savoia, C.5
Licci, M.6
Tolnay, M.7
Frank, S.8
Scorrano, L.9
-
117
-
-
78651302188
-
Bcl-2 family interaction with the mitochondrial morphogenesis machinery
-
[117] Cleland, M.M., Norris, K.L., Karbowski, M., Wang, C., Suen, D.F., Jiao, S., George, N.M., Luo, X., Li, Z., Youle, R.J., Bcl-2 family interaction with the mitochondrial morphogenesis machinery. Cell Death Differ. 18 (2011), 235–247.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 235-247
-
-
Cleland, M.M.1
Norris, K.L.2
Karbowski, M.3
Wang, C.4
Suen, D.F.5
Jiao, S.6
George, N.M.7
Luo, X.8
Li, Z.9
Youle, R.J.10
-
118
-
-
84913582205
-
Novel roles for actin in mitochondrial fission
-
[118] Hatch, A.L., Gurel, P.S., Higgs, H.N., Novel roles for actin in mitochondrial fission. J. Cell Sci. 127 (2014), 4549–4560.
-
(2014)
J. Cell Sci.
, vol.127
, pp. 4549-4560
-
-
Hatch, A.L.1
Gurel, P.S.2
Higgs, H.N.3
-
119
-
-
84857873334
-
Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis
-
[119] Chipuk, J.E., McStay, G.P., Bharti, A., Kuwana, T., Clarke, C.J., Siskind, L.J., Obeid, L.M., Green, D.R., Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis. Cell 148 (2012), 988–1000.
-
(2012)
Cell
, vol.148
, pp. 988-1000
-
-
Chipuk, J.E.1
McStay, G.P.2
Bharti, A.3
Kuwana, T.4
Clarke, C.J.5
Siskind, L.J.6
Obeid, L.M.7
Green, D.R.8
-
120
-
-
79959305691
-
Mitochondria: the next (neurode)generation
-
[120] Schon, E.A., Przedborski, S., Mitochondria: the next (neurode)generation. Neuron 70 (2011), 1033–1053.
-
(2011)
Neuron
, vol.70
, pp. 1033-1053
-
-
Schon, E.A.1
Przedborski, S.2
-
121
-
-
57349100367
-
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
-
[121] de Brito, O.M., Scorrano, L., Mitofusin 2 tethers endoplasmic reticulum to mitochondria. Nature 456 (2008), 605–610.
-
(2008)
Nature
, vol.456
, pp. 605-610
-
-
de Brito, O.M.1
Scorrano, L.2
-
122
-
-
79551600416
-
Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction
-
[122] Iwasawa, R., Mahul-Mellier, A.L., Datler, C., Pazarentzos, E., Grimm, S., Fis1 and Bap31 bridge the mitochondria-ER interface to establish a platform for apoptosis induction. EMBO J. 30 (2011), 556–568.
-
(2011)
EMBO J.
, vol.30
, pp. 556-568
-
-
Iwasawa, R.1
Mahul-Mellier, A.L.2
Datler, C.3
Pazarentzos, E.4
Grimm, S.5
-
123
-
-
84963819006
-
Combination therapy induces unfolded protein response and cytoskeletal rearrangement leading to mitochondrial apoptosis in prostate cancer
-
[123] Kumar, S., Chaudhary, A.K., Kumar, R., O'Malley, J., Dubrovska, A., Wang, X., Yadav, N., Goodrich, D.W., Chandra, D., Combination therapy induces unfolded protein response and cytoskeletal rearrangement leading to mitochondrial apoptosis in prostate cancer. Mol. Oncol. 10 (2016), 949–965.
-
(2016)
Mol. Oncol.
, vol.10
, pp. 949-965
-
-
Kumar, S.1
Chaudhary, A.K.2
Kumar, R.3
O'Malley, J.4
Dubrovska, A.5
Wang, X.6
Yadav, N.7
Goodrich, D.W.8
Chandra, D.9
-
124
-
-
84967261775
-
Mitochondrial dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in African-American men with prostate cancer
-
[124] Chaudhary, A.K., Bhat, T.A., Kumar, S., Kumar, A., Kumar, R., Underwood, W., Koochekpour, S., Shourideh, M., Yadav, N., Dhar, S., Chandra, D., Mitochondrial dysfunction-mediated apoptosis resistance associates with defective heat shock protein response in African-American men with prostate cancer. Br. J. Cancer 114 (2016), 1090–1100.
-
(2016)
Br. J. Cancer
, vol.114
, pp. 1090-1100
-
-
Chaudhary, A.K.1
Bhat, T.A.2
Kumar, S.3
Kumar, A.4
Kumar, R.5
Underwood, W.6
Koochekpour, S.7
Shourideh, M.8
Yadav, N.9
Dhar, S.10
Chandra, D.11
-
125
-
-
79952042622
-
Endoplasmic reticulum stress mediates withaferin A-induced apoptosis in human renal carcinoma cells
-
[125] Choi, M.J., Park, E.J., Min, K.J., Park, J.W., Kwon, T.K., Endoplasmic reticulum stress mediates withaferin A-induced apoptosis in human renal carcinoma cells. Toxicol. in Vitro 25 (2011), 692–698.
-
(2011)
Toxicol. in Vitro
, vol.25
, pp. 692-698
-
-
Choi, M.J.1
Park, E.J.2
Min, K.J.3
Park, J.W.4
Kwon, T.K.5
-
126
-
-
84978513118
-
Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells
-
[126] Li, X., Zhu, F., Jiang, J., Sun, C., Zhong, Q., Shen, M., Wang, X., Tian, R., Shi, C., Xu, M., Peng, F., Guo, X., Hu, J., Ye, D., Wang, M., Qin, R., Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells. Autophagy 12 (2016), 1521–1537.
-
(2016)
Autophagy
, vol.12
, pp. 1521-1537
-
-
Li, X.1
Zhu, F.2
Jiang, J.3
Sun, C.4
Zhong, Q.5
Shen, M.6
Wang, X.7
Tian, R.8
Shi, C.9
Xu, M.10
Peng, F.11
Guo, X.12
Hu, J.13
Ye, D.14
Wang, M.15
Qin, R.16
-
127
-
-
84940101852
-
ROS accumulation by PEITC selectively kills ovarian cancer cells via UPR-mediated apoptosis
-
[127] Hong, Y.H., Uddin, M.H., Jo, U., Kim, B., Song, J., Suh, D.H., Kim, H.S., Song, Y.S., ROS accumulation by PEITC selectively kills ovarian cancer cells via UPR-mediated apoptosis. Front. Oncol., 5, 2015, 167.
-
(2015)
Front. Oncol.
, vol.5
, pp. 167
-
-
Hong, Y.H.1
Uddin, M.H.2
Jo, U.3
Kim, B.4
Song, J.5
Suh, D.H.6
Kim, H.S.7
Song, Y.S.8
-
128
-
-
84978200057
-
Silibinin induces mitochondrial NOX4-mediated endoplasmic reticulum stress response and its subsequent apoptosis
-
[128] Kim, S.H., Kim, K.Y., Yu, S.N., Seo, Y.K., Chun, S.S., Yu, H.S., Ahn, S.C., Silibinin induces mitochondrial NOX4-mediated endoplasmic reticulum stress response and its subsequent apoptosis. BMC Cancer, 16, 2016, 452.
-
(2016)
BMC Cancer
, vol.16
, pp. 452
-
-
Kim, S.H.1
Kim, K.Y.2
Yu, S.N.3
Seo, Y.K.4
Chun, S.S.5
Yu, H.S.6
Ahn, S.C.7
-
129
-
-
84942533985
-
Resveratrol activates autophagic cell death in prostate cancer cells via downregulation of STIM1 and the mTOR pathway
-
[129] Selvaraj, S., Sun, Y., Sukumaran, P., Singh, B.B., Resveratrol activates autophagic cell death in prostate cancer cells via downregulation of STIM1 and the mTOR pathway. Mol. Carcinog. 55 (2016), 818–831.
-
(2016)
Mol. Carcinog.
, vol.55
, pp. 818-831
-
-
Selvaraj, S.1
Sun, Y.2
Sukumaran, P.3
Singh, B.B.4
-
130
-
-
84944686104
-
ER-stress-induced differentiation sensitizes colon cancer stem cells to chemotherapy
-
[130] Wielenga, M.C., Colak, S., Heijmans, J., van Lidth de Jeude, J.F., Rodermond, H.M., Paton, J.C., Paton, A.W., Vermeulen, L., Medema, J.P., van den Brink, G.R., ER-stress-induced differentiation sensitizes colon cancer stem cells to chemotherapy. Cell Rep. 13 (2015), 490–494.
-
(2015)
Cell Rep.
, vol.13
, pp. 490-494
-
-
Wielenga, M.C.1
Colak, S.2
Heijmans, J.3
van Lidth de Jeude, J.F.4
Rodermond, H.M.5
Paton, J.C.6
Paton, A.W.7
Vermeulen, L.8
Medema, J.P.9
van den Brink, G.R.10
-
131
-
-
21244461140
-
Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species
-
[131] Singh, S.V., Srivastava, S.K., Choi, S., Lew, K.L., Antosiewicz, J., Xiao, D., Zeng, Y., Watkins, S.C., Johnson, C.S., Trump, D.L., Lee, Y.J., Xiao, H., Herman-Antosiewicz, A., Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species. J. Biol. Chem. 280 (2005), 19911–19924.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 19911-19924
-
-
Singh, S.V.1
Srivastava, S.K.2
Choi, S.3
Lew, K.L.4
Antosiewicz, J.5
Xiao, D.6
Zeng, Y.7
Watkins, S.C.8
Johnson, C.S.9
Trump, D.L.10
Lee, Y.J.11
Xiao, H.12
Herman-Antosiewicz, A.13
-
132
-
-
84902585373
-
Cantharidin induces apoptosis of H460 human lung cancer cells through mitochondria-dependent pathways
-
[132] Hsia, T.C., Yu, C.C., Hsu, S.C., Tang, N.Y., Lu, H.F., Huang, Y.P., Wu, S.H., Lin, J.G., Chung, J.G., Cantharidin induces apoptosis of H460 human lung cancer cells through mitochondria-dependent pathways. Int. J. Oncol. 45 (2014), 245–254.
-
(2014)
Int. J. Oncol.
, vol.45
, pp. 245-254
-
-
Hsia, T.C.1
Yu, C.C.2
Hsu, S.C.3
Tang, N.Y.4
Lu, H.F.5
Huang, Y.P.6
Wu, S.H.7
Lin, J.G.8
Chung, J.G.9
-
133
-
-
84882735039
-
Perturbation of proteasome function by bortezomib leading to ER stress-induced apoptotic cell death in cholangiocarcinoma
-
[133] Vaeteewoottacharn, K., Kariya, R., Matsuda, K., Taura, M., Wongkham, C., Wongkham, S., Okada, S., Perturbation of proteasome function by bortezomib leading to ER stress-induced apoptotic cell death in cholangiocarcinoma. J. Cancer Res. Clin. Oncol. 139 (2013), 1551–1562.
-
(2013)
J. Cancer Res. Clin. Oncol.
, vol.139
, pp. 1551-1562
-
-
Vaeteewoottacharn, K.1
Kariya, R.2
Matsuda, K.3
Taura, M.4
Wongkham, C.5
Wongkham, S.6
Okada, S.7
-
134
-
-
84875235453
-
Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity
-
[134] Atkins, C., Liu, Q., Minthorn, E., Zhang, S.Y., Figueroa, D.J., Moss, K., Stanley, T.B., Sanders, B., Goetz, A., Gaul, N., Choudhry, A.E., Alsaid, H., Jucker, B.M., Axten, J.M., Kumar, R., Characterization of a novel PERK kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res. 73 (2013), 1993–2002.
-
(2013)
Cancer Res.
, vol.73
, pp. 1993-2002
-
-
Atkins, C.1
Liu, Q.2
Minthorn, E.3
Zhang, S.Y.4
Figueroa, D.J.5
Moss, K.6
Stanley, T.B.7
Sanders, B.8
Goetz, A.9
Gaul, N.10
Choudhry, A.E.11
Alsaid, H.12
Jucker, B.M.13
Axten, J.M.14
Kumar, R.15
-
135
-
-
4444302042
-
Effect on tumor cells of blocking survival response to glucose deprivation
-
[135] Park, H.R., Tomida, A., Sato, S., Tsukumo, Y., Yun, J., Yamori, T., Hayakawa, Y., Tsuruo, T., Shin-ya, K., Effect on tumor cells of blocking survival response to glucose deprivation. J. Natl. Cancer Inst. 96 (2004), 1300–1310.
-
(2004)
J. Natl. Cancer Inst.
, vol.96
, pp. 1300-1310
-
-
Park, H.R.1
Tomida, A.2
Sato, S.3
Tsukumo, Y.4
Yun, J.5
Yamori, T.6
Hayakawa, Y.7
Tsuruo, T.8
Shin-ya, K.9
-
136
-
-
84977561257
-
Tunicamycin-induced endoplasmic reticulum stress reduces in vitro subpopulation and invasion of CD44 +/CD24 − phenotype breast cancer stem cells
-
[136] Nami, B., Donmez, H., Kocak, N., Tunicamycin-induced endoplasmic reticulum stress reduces in vitro subpopulation and invasion of CD44 +/CD24 − phenotype breast cancer stem cells. Exp. Toxicol. Pathol. 68 (2016), 419–426.
-
(2016)
Exp. Toxicol. Pathol.
, vol.68
, pp. 419-426
-
-
Nami, B.1
Donmez, H.2
Kocak, N.3
|