Downregulation of E2F1 during ER stress is required to induce apoptosis

Journal of Cell Science

Volumn 128, Issue 6, 2015, Pages 1166-1179

  Pagliarini, Vittoria ^a,b,e   Giglio, Paola ^a   Bernardoni, Paolo ^a   Zio, Daniela De ^b,c   Fimia, Gian Maria ^a,d   Piacentini, Mauro ^a,b   Corazzari, Marco ^a,b  

^a NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^b UNIVERSITY OF ROME TOR VERGATA   (Italy)

^c DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

^d UNIVERSITY OF SALENTO   (Italy)

^e IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

Apoptosis; ATF6; E2F; ER stress; UPR

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; BH3 PROTEIN; PROTEIN IRE1; PROTEIN NOXA; PUMA PROTEIN; THAPSIGARGIN; TRANSCRIPTION FACTOR E2F1; TRANSCRIPTION FACTOR E2F7; TUNICAMYCIN; X BOX BINDING PROTEIN 1; APOPTOSIS REGULATORY PROTEIN; ATF6 PROTEIN, HUMAN; BBC3 PROTEIN, HUMAN; E2F1 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; MESSENGER RNA; ONCOPROTEIN; PMAIP1 PROTEIN, HUMAN; PROTEIN BCL 2; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL POPULATION; CELL SURVIVAL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENDOPLASMIC RETICULUM MEMBRANE; ENDOPLASMIC RETICULUM STRESS; FIBROSARCOMA CELL LINE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RNA INTERFERENCE; SAOS 2 CELL LINE; TRANSCRIPTION INITIATION SITE; TRANSIENT TRANSFECTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; BONE TUMOR; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; ENZYME IMMUNOASSAY; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; MELANOMA; METABOLISM; OSTEOSARCOMA; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ACTIVATING TRANSCRIPTION FACTOR 6; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BLOTTING, WESTERN; BONE NEOPLASMS; CELL PROLIFERATION; CELLS, CULTURED; E2F1 TRANSCRIPTION FACTOR; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FIBROBLASTS; GENE EXPRESSION REGULATION; HUMANS; IMMUNOENZYME TECHNIQUES; MELANOMA; OSTEOSARCOMA; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84925397246     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.164103     Document Type: Article

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