Controlling the unfolded protein response-mediated life and death decisions in cancer

Seminars in Cancer Biology

Volumn 33, Issue , 2015, Pages 57-66

  Maurel, Marion ^a,c   McGrath, Eoghan P ^a   Mnich, Katarzyna ^a   Healy, Sandra ^a   Chevet, Eric ^b,c   Samali, Afshin ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c Centre de Lutte Contre Le Cancer Eugène Marquis   (France)

Author keywords

Apoptosis; Cancer; Cell death; ER stress; UPR

Indexed keywords

16F 16; ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; APY 29; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GSK 2606414; GSK 2656157; GUANABENZ; IMATINIB; INITIATION FACTOR 2ALPHA; INTEGRATED STRESS RESPONSE INHIBITOR; ISOMERASE INHIBITOR; MESSENGER RNA; MKC 3946; P 1; PACMA 31; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN DISULFIDE ISOMERASE; PROTEIN IRE1; RB 11CA; RIBONUCLEASE INHIBITOR; SALUBRINAL; SERINE PROTEINASE INHIBITOR; STF 083010; SUNITINIB; TOYOCAMYCIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; ADENOSINE TRIPHOSPHATE; ATF6 PROTEIN, HUMAN; ERN1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

APOPTOSIS; BINDING AFFINITY; CANCER INHIBITION; CARCINOGENESIS; CELL ACTIVATION; CELL ONCOGENE; CELL SURVIVAL; CELLULAR STRESS RESPONSE; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TARGETING; ENDOPLASMIC RETICULUM STRESS; HOMEOSTASIS; HUMAN; LIFE; MALIGNANT TRANSFORMATION; MOLECULAR MECHANICS; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; REVIEW; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; TUMOR MICROENVIRONMENT; UNFOLDED PROTEIN RESPONSE; ANIMAL; CELL LINEAGE; CELL TRANSFORMATION; CHEMISTRY; ENDOPLASMIC RETICULUM; METABOLISM; NEOPLASM; PATHOLOGY;

ACTIVATING TRANSCRIPTION FACTOR 6; ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CELL LINEAGE; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; HOMEOSTASIS; HUMANS; NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EID: 84938207247     PISSN: 1044579X     EISSN: 10963650     Source Type: Journal    
DOI: 10.1016/j.semcancer.2015.03.003     Document Type: Review

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