메뉴 건너뛰기




Volumn 7, Issue 15, 2016, Pages 2346-2359

Obesity and cancer: The role of adipose tissue and adipo-cytokines-induced chronic inflammation

Author keywords

Adipocytes inflammation; Adipocytokine; Cancer; Obesity

Indexed keywords

ADIPOCYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; LEPTIN; TUMOR NECROSIS FACTOR;

EID: 85008154360     PISSN: None     EISSN: 18379664     Source Type: Journal    
DOI: 10.7150/jca.16884     Document Type: Review
Times cited : (237)

References (220)
  • 1
    • 33846422032 scopus 로고    scopus 로고
    • Obesity and diabetes in the developing world-a growing challenge
    • Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world-a growing challenge. N Engl J Med 2007; 356: 213-215.
    • (2007) N Engl J Med , vol.356 , pp. 213-215
    • Hossain, P.1    Kawar, B.2    El Nahas, M.3
  • 2
    • 84940476834 scopus 로고    scopus 로고
    • Insulin resistance, glucose intolerance and diabetes mellitus in obstructive sleep apnoea
    • Kent BD, McNicholas WT, Ryan S. Insulin resistance, glucose intolerance and diabetes mellitus in obstructive sleep apnoea. J Thorac Dis 2015; 7(8): 1343-1357.
    • (2015) J Thorac Dis , vol.7 , Issue.8 , pp. 1343-1357
    • Kent, B.D.1    McNicholas, W.T.2    Ryan, S.3
  • 3
    • 84947940401 scopus 로고    scopus 로고
    • Body mass index in early and middle adult life: prospective associations with myocardial infarction, stroke and diabetes over a 30-year period: the British Regional Heart Study
    • Owen CG, Kapetanakis VV, Rudnicka AR, et al. Body mass index in early and middle adult life: prospective associations with myocardial infarction, stroke and diabetes over a 30-year period: the British Regional Heart Study. BMJ Open 2015; 5(9): e008105. doi: 10.1136/bmjopen-2015-008105.
    • (2015) BMJ Open , vol.5 , Issue.9
    • Owen, C.G.1    Kapetanakis, V.V.2    Rudnicka, A.R.3
  • 5
    • 84856487711 scopus 로고    scopus 로고
    • Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
    • Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 2012; 307: 491-497.
    • (2012) JAMA , vol.307 , pp. 491-497
    • Flegal, K.M.1    Carroll, M.D.2    Kit, B.K.3    Ogden, C.L.4
  • 6
    • 0037464510 scopus 로고    scopus 로고
    • Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S
    • Calle EE, Rodriguez C, Walker-Thurmond K, Thun MJ. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults. N Engl J Med 2003; 348: 1625-1638.
    • (2003) adults. N Engl J Med , vol.348 , pp. 1625-1638
    • Calle, E.E.1    Rodriguez, C.2    Walker-Thurmond, K.3    Thun, M.J.4
  • 7
    • 83255162608 scopus 로고    scopus 로고
    • Prognostic impact of body mass index stratified by smoking status in patients with esophageal adenocarcinoma
    • Yoon HH, Lewis MA, Shi Q, et al. Prognostic impact of body mass index stratified by smoking status in patients with esophageal adenocarcinoma. J Clin Oncol 2011; 29: 4561-4567.
    • (2011) J Clin Oncol , vol.29 , pp. 4561-4567
    • Yoon, H.H.1    Lewis, M.A.2    Shi, Q.3
  • 8
    • 84958890227 scopus 로고    scopus 로고
    • The influence of obesity on survival in early, high-risk breast cancer: results from the randomized SUCCESS A trial
    • Widschwendter P, Friedl TW, Schwentner L, et al. The influence of obesity on survival in early, high-risk breast cancer: results from the randomized SUCCESS A trial. Breast Cancer Res 2015; 17: 129.
    • (2015) Breast Cancer Res , vol.17 , pp. 129
    • Widschwendter, P.1    Friedl, T.W.2    Schwentner, L.3
  • 9
    • 84932196847 scopus 로고    scopus 로고
    • Body mass index and mortality in men with prostate cancer
    • Cantarutti A, Bonn SE, Adami HO, et al. Body mass index and mortality in men with prostate cancer. Prostate 2015; 75(11): 1129-1136.
    • (2015) Prostate , vol.75 , Issue.11 , pp. 1129-1136
    • Cantarutti, A.1    Bonn, S.E.2    Adami, H.O.3
  • 10
    • 84897423681 scopus 로고    scopus 로고
    • Defining an epidemic: the body mass index in British and US obesity research 1960-2000
    • Fletcher I. Defining an epidemic: the body mass index in British and US obesity research 1960-2000. Sociol Health Illn 2014; 36(3): 338-353.
    • (2014) Sociol Health Illn , vol.36 , Issue.3 , pp. 338-353
    • Fletcher, I.1
  • 11
    • 2942650969 scopus 로고    scopus 로고
    • Adipose tissue as an endocrine organ
    • Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metab 2004; 89(6): 2548-2556.
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.6 , pp. 2548-2556
    • Kershaw, E.E.1    Flier, J.S.2
  • 13
    • 77952888280 scopus 로고    scopus 로고
    • The development and endocrine functions of adipose tissue
    • Poulos SP, Hausman DB, Hausman GJ. The development and endocrine functions of adipose tissue. Mol Cell Endocrinol 2010; 323(1): 20-34.
    • (2010) Mol Cell Endocrinol , vol.323 , Issue.1 , pp. 20-34
    • Poulos, S.P.1    Hausman, D.B.2    Hausman, G.J.3
  • 14
    • 81855209246 scopus 로고    scopus 로고
    • Adipose tissue-derived progenitor cells and cancer
    • Zhang Y, Bellows CF, Kolonin MG. Adipose tissue-derived progenitor cells and cancer. World J Stem Cells 2010; 2(5): 103-113.
    • (2010) World J Stem Cells , vol.2 , Issue.5 , pp. 103-113
    • Zhang, Y.1    Bellows, C.F.2    Kolonin, M.G.3
  • 15
    • 80054911514 scopus 로고    scopus 로고
    • Forming functional fat: a growing understanding of adipocyte differentiation
    • Cristancho AG, Lazar MA. Forming functional fat: a growing understanding of adipocyte differentiation. Nat Rev Mol Cell Biol 2011; 12(11): 722-734.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , Issue.11 , pp. 722-734
    • Cristancho, A.G.1    Lazar, M.A.2
  • 17
    • 55249098186 scopus 로고    scopus 로고
    • White adipose tissue as endocrine organ and its role in obesity
    • Vázquez-Vela ME, Torres N, Tovar AR. White adipose tissue as endocrine organ and its role in obesity. Arch Med Res 2008; 39(8): 715-728.
    • (2008) Arch Med Res , vol.39 , Issue.8 , pp. 715-728
    • Vázquez-Vela, M.E.1    Torres, N.2    Tovar, A.R.3
  • 18
    • 84893717340 scopus 로고    scopus 로고
    • Adipose tissue: cell heterogeneity and functional diversity
    • Esteve Ràfols M. Adipose tissue: cell heterogeneity and functional diversity. Endocrinol Nutr 2014; 61(2): 100-112.
    • (2014) Endocrinol Nutr , vol.61 , Issue.2 , pp. 100-112
    • Esteve Ràfols, M.1
  • 20
    • 84936123107 scopus 로고    scopus 로고
    • The use of measures of obesity in childhood for predicting obesity and the development of obesity-related diseases in adulthood: a systematic review and meta-analysis
    • Simmonds M, Burch J, Llewellyn A, et al. The use of measures of obesity in childhood for predicting obesity and the development of obesity-related diseases in adulthood: a systematic review and meta-analysis. Health Technol Assess 2015; 19(43): 1-336.
    • (2015) Health Technol Assess , vol.19 , Issue.43 , pp. 1-336
    • Simmonds, M.1    Burch, J.2    Llewellyn, A.3
  • 21
    • 85008174938 scopus 로고    scopus 로고
    • Adipocyte size as a determinant of metabolic disease and adipose tissue dysfunction
    • Laforest S, Labrecque J, Michaud A, et al. Adipocyte size as a determinant of metabolic disease and adipose tissue dysfunction. Crit Rev Clin Lab Sci 2015; 18: 1-13.
    • (2015) Crit Rev Clin Lab Sci , vol.18 , pp. 1-13
    • Laforest, S.1    Labrecque, J.2    Michaud, A.3
  • 22
    • 84905389366 scopus 로고    scopus 로고
    • Overweight and Obesity before, during and after Pregnancy: Part 1: Pathophysiology, Molecular Biology and Epigenetic Consequences
    • Stupin JH, Arabin B. Overweight and Obesity before, during and after Pregnancy: Part 1: Pathophysiology, Molecular Biology and Epigenetic Consequences. Geburtshilfe Frauenheilkd 2014; 74(7): 639-645.
    • (2014) Geburtshilfe Frauenheilkd , vol.74 , Issue.7 , pp. 639-645
    • Stupin, J.H.1    Arabin, B.2
  • 23
    • 85027941463 scopus 로고    scopus 로고
    • Central obesity as a clinical marker of adiposopathy; increased visceral adiposity as a surrogate marker for global fat dysfunction
    • Bays H. Central obesity as a clinical marker of adiposopathy; increased visceral adiposity as a surrogate marker for global fat dysfunction. Curr Opin Endocrinol Diabetes Obes 2014; 21(5): 345-351.
    • (2014) Curr Opin Endocrinol Diabetes Obes , vol.21 , Issue.5 , pp. 345-351
    • Bays, H.1
  • 25
    • 84886744093 scopus 로고    scopus 로고
    • Hypoxia-mimetic effects in the secretome of human preadipocytes and adipocytes
    • Rosenow A, Noben JP, Bouwman FG, et al. Hypoxia-mimetic effects in the secretome of human preadipocytes and adipocytes. Biochim Biophys Acta 2013; 1834(12): 2761-2771.
    • (2013) Biochim Biophys Acta , vol.1834 , Issue.12 , pp. 2761-2771
    • Rosenow, A.1    Noben, J.P.2    Bouwman, F.G.3
  • 26
    • 42449097289 scopus 로고    scopus 로고
    • Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
    • Guilherme A, Virbasius JV, Puri V, Czech MP. Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol 2008; 9: 367-377.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 367-377
    • Guilherme, A.1    Virbasius, J.V.2    Puri, V.3    Czech, M.P.4
  • 27
    • 84870218548 scopus 로고    scopus 로고
    • Obesity, energy balance, and cancer: new opportunities for prevention
    • Hursting SD, Digiovanni J, Dannenberg AJ, et al. Obesity, energy balance, and cancer: new opportunities for prevention. Cancer Prev Res 2012; 5: 1260-1272.
    • (2012) Cancer Prev Res , vol.5 , pp. 1260-1272
    • Hursting, S.D.1    Digiovanni, J.2    Dannenberg, A.J.3
  • 28
    • 84885186816 scopus 로고    scopus 로고
    • Adipose tissue and adipocytes support tumorigenesis and metastasis
    • Nieman KM, Romero IL, Van Houten B, Lengyel E. Adipose tissue and adipocytes support tumorigenesis and metastasis. Biochim Biophys Acta 2013; 1831(10): 1533-1541.
    • (2013) Biochim Biophys Acta , vol.1831 , Issue.10 , pp. 1533-1541
    • Nieman, K.M.1    Romero, I.L.2    Van Houten, B.3    Lengyel, E.4
  • 29
    • 84926124903 scopus 로고    scopus 로고
    • Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: effect of tumor microenvironment
    • Almendros I, Gileles-Hillel A, Khalyfa A, et al. Adipose tissue macrophage polarization by intermittent hypoxia in a mouse model of OSA: effect of tumor microenvironment. Cancer Lett 2015; 361(2):233-239.
    • (2015) Cancer Lett , vol.361 , Issue.2 , pp. 233-239
    • Almendros, I.1    Gileles-Hillel, A.2    Khalyfa, A.3
  • 30
    • 84873684881 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1a regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes
    • Jiang C, Kim JH, Li F, et al. Hypoxia-inducible factor 1a regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes. J Biol Chem 2013; 288(6): 3844-3857.
    • (2013) J Biol Chem , vol.288 , Issue.6 , pp. 3844-3857
    • Jiang, C.1    Kim, J.H.2    Li, F.3
  • 31
    • 84949008086 scopus 로고    scopus 로고
    • Hypoxia Promotes the Inflammatory Response and Stemness Features in Visceral Fat Stem Cells from Obese Subjects
    • Petrangeli E, Coroniti G, Brini AT, et al. Hypoxia Promotes the Inflammatory Response and Stemness Features in Visceral Fat Stem Cells from Obese Subjects. J Cell Physiol 2016; 231(3): 668-679.
    • (2016) J Cell Physiol , vol.231 , Issue.3 , pp. 668-679
    • Petrangeli, E.1    Coroniti, G.2    Brini, A.T.3
  • 32
    • 85027941463 scopus 로고    scopus 로고
    • Central obesity as a clinical marker of adiposopathy; increased visceral adiposity as a surrogate marker for global fat dysfunction
    • Bays H. Central obesity as a clinical marker of adiposopathy; increased visceral adiposity as a surrogate marker for global fat dysfunction. Curr Opin Endocrinol Diabetes Obes 2014; 21(5): 345-351.
    • (2014) Curr Opin Endocrinol Diabetes Obes , vol.21 , Issue.5 , pp. 345-351
    • Bays, H.1
  • 33
    • 84902075318 scopus 로고    scopus 로고
    • Increased adipocyte O2 consumption triggers HIF-1a, causing inflammation and insulin resistance in obesity
    • Lee YS, Kim JW, Osborne O, et al. Increased adipocyte O2 consumption triggers HIF-1a, causing inflammation and insulin resistance in obesity. Cell 2014; 157(6): 1339-1352.
    • (2014) Cell , vol.157 , Issue.6 , pp. 1339-1352
    • Lee, Y.S.1    Kim, J.W.2    Osborne, O.3
  • 34
    • 84904611773 scopus 로고    scopus 로고
    • Hypoxia and adipocyte physiology: implications for adipose tissue dysfunction in obesity
    • Trayhurn P. Hypoxia and adipocyte physiology: implications for adipose tissue dysfunction in obesity. Annu Rev Nutr 2014; 34: 207-236.
    • (2014) Annu Rev Nutr , vol.34 , pp. 207-236
    • Trayhurn, P.1
  • 36
    • 84928650407 scopus 로고    scopus 로고
    • Adipose tissue dysfunction and its effects on tumor metabolism
    • Diedrich J, Gusky HC, Podgorski I. Adipose tissue dysfunction and its effects on tumor metabolism. Horm Mol Biol Clin Investig 2015; 21(1): 17-41.
    • (2015) Horm Mol Biol Clin Investig , vol.21 , Issue.1 , pp. 17-41
    • Diedrich, J.1    Gusky, H.C.2    Podgorski, I.3
  • 37
    • 84877349617 scopus 로고    scopus 로고
    • Common mechanisms of dysfunctional adipose tissue and obesity-related cancers
    • Matafome P, Santos-Silva D, Sena CM, Seiça R. Common mechanisms of dysfunctional adipose tissue and obesity-related cancers. Diabetes Metab Res Rev 2013; 29(4): 285-295.
    • (2013) Diabetes Metab Res Rev , vol.29 , Issue.4 , pp. 285-295
    • Matafome, P.1    Santos-Silva, D.2    Sena, C.M.3    Seiça, R.4
  • 38
    • 84903278004 scopus 로고    scopus 로고
    • Expressions of hypoxia-inducible factor-1 and epithelial cell adhesion molecule are linked with aggressive local recurrence of hepatocellular carcinoma after radiofrequency ablation therapy
    • Yamada S, Utsunomiya T, Morine Y, et al. Expressions of hypoxia-inducible factor-1 and epithelial cell adhesion molecule are linked with aggressive local recurrence of hepatocellular carcinoma after radiofrequency ablation therapy. Ann Surg Oncol 2014; 21 Suppl 3: S436-442
    • (2014) Ann Surg Oncol , vol.21 , pp. 436-442
    • Yamada, S.1    Utsunomiya, T.2    Morine, Y.3
  • 39
    • 84870941135 scopus 로고    scopus 로고
    • Hypoxia-regulated target genes implicated in tumor metastasis
    • Tsai YP, Wu KJ. Hypoxia-regulated target genes implicated in tumor metastasis. J Biomed Sci 2012; 19: 102.
    • (2012) J Biomed Sci , vol.19 , pp. 102
    • Tsai, Y.P.1    Wu, K.J.2
  • 40
    • 79954995170 scopus 로고    scopus 로고
    • Pathophysiological response to hypoxia -from the molecular mechanisms of malady to drug discovery: hypoxia-inducible factor-1 (HIF-1)-active cells as a target for cancer therapy
    • Kizaka-Kondoh S, Kuchimaru T, Kadonosono T. Pathophysiological response to hypoxia -from the molecular mechanisms of malady to drug discovery: hypoxia-inducible factor-1 (HIF-1)-active cells as a target for cancer therapy. J Pharmacol Sci 2011; 115(4): 440-445.
    • (2011) J Pharmacol Sci , vol.115 , Issue.4 , pp. 440-445
    • Kizaka-Kondoh, S.1    Kuchimaru, T.2    Kadonosono, T.3
  • 41
    • 79954991372 scopus 로고    scopus 로고
    • Pathophysiological response to hypoxia -from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment
    • Nagasawa H. Pathophysiological response to hypoxia -from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment. J Pharmacol Sci 2011; 115(4): 446-452
    • (2011) J Pharmacol Sci , vol.115 , Issue.4 , pp. 446-452
    • Nagasawa, H.1
  • 42
    • 84940953781 scopus 로고    scopus 로고
    • The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation
    • Wensveen FM, Valentic S, Šestan M, et al. The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation. Eur J Immunol 2015; 45(9): 2446-2456.
    • (2015) Eur J Immunol , vol.45 , Issue.9 , pp. 2446-2456
    • Wensveen, F.M.1    Valentic, S.2    Šestan, M.3
  • 43
    • 84901424065 scopus 로고    scopus 로고
    • Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity
    • Huh JY, Park YJ, Ham M, Kim JB. Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity. Mol Cells 2014; 37(5): 365-371.
    • (2014) Mol Cells , vol.37 , Issue.5 , pp. 365-371
    • Huh, J.Y.1    Park, Y.J.2    Ham, M.3    Kim, J.B.4
  • 45
    • 77955404414 scopus 로고    scopus 로고
    • The role of adipose tissue and adipokines in obesity-related inflammatory diseases
    • Balistreri CR, Caruso C, Candore G. The role of adipose tissue and adipokines in obesity-related inflammatory diseases. Mediators Inflamm 2010; 2010:802078. doi: 10.1155/2010/802078.
    • (2010) Mediators Inflamm , vol.2010
    • Balistreri, C.R.1    Caruso, C.2    Candore, G.3
  • 46
    • 79151484704 scopus 로고    scopus 로고
    • Adipokines in inflammation and metabolic disease
    • Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol 2011; 11(2): 85-97.
    • (2011) Nat Rev Immunol , vol.11 , Issue.2 , pp. 85-97
    • Ouchi, N.1    Parker, J.L.2    Lugus, J.J.3    Walsh, K.4
  • 48
    • 84885783040 scopus 로고    scopus 로고
    • Clinical insights from adiponectin analysis in breast cancer patients reveal its anti-inflammatory properties in non-obese women
    • Panis C, Herrera AC, Aranome AM, et al. Clinical insights from adiponectin analysis in breast cancer patients reveal its anti-inflammatory properties in non-obese women. Mol Cell Endocrinol 2014; 382(1): 190-196.
    • (2014) Mol Cell Endocrinol , vol.382 , Issue.1 , pp. 190-196
    • Panis, C.1    Herrera, A.C.2    Aranome, A.M.3
  • 49
    • 0042466384 scopus 로고    scopus 로고
    • Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans
    • Bruun JM, Lihn AS, Verdich C, et al. Regulation of adiponectin by adipose tissue-derived cytokines: in vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab 2003; 285: E527-E533.
    • (2003) Am J Physiol Endocrinol Metab , vol.285 , pp. E527-E533
    • Bruun, J.M.1    Lihn, A.S.2    Verdich, C.3
  • 50
    • 84938925308 scopus 로고    scopus 로고
    • Adipose Tissue as an Endocrine Organ: An Update on Pro-inflammatory and Anti-inflammatory Microenvironment
    • Smitka K, Marešová D. Adipose Tissue as an Endocrine Organ: An Update on Pro-inflammatory and Anti-inflammatory Microenvironment. Prague Med Rep 2015; 116(2): 87-111.
    • (2015) Prague Med Rep , vol.116 , Issue.2 , pp. 87-111
    • Smitka, K.1    Marešová, D.2
  • 51
    • 84867350954 scopus 로고    scopus 로고
    • Obesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issue
    • Hursting SD, Dunlap SM. Obesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issue. Ann NY Acad Sci 2012; 1271: 82-87.
    • (2012) Ann NY Acad Sci , vol.1271 , pp. 82-87
    • Hursting, S.D.1    Dunlap, S.M.2
  • 52
    • 84893722362 scopus 로고    scopus 로고
    • Adipose tissue and adipocyte dysregulation
    • Lafontan M. Adipose tissue and adipocyte dysregulation. Diabetes Metab 2014, 40(1): 16-28.
    • (2014) Diabetes Metab , vol.40 , Issue.1 , pp. 16-28
    • Lafontan, M.1
  • 53
    • 77949329629 scopus 로고    scopus 로고
    • Cellular hypoxia and adipose tissue dysfunction in obesity
    • Wood IS, de Heredia FP, Wang B, Trayhurn P. Cellular hypoxia and adipose tissue dysfunction in obesity. Proc Nutr Soc 2009; 68(4): 370-377.
    • (2009) Proc Nutr Soc , vol.68 , Issue.4 , pp. 370-377
    • Wood, I.S.1    de Heredia, F.P.2    Wang, B.3    Trayhurn, P.4
  • 54
    • 44849116310 scopus 로고    scopus 로고
    • The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences
    • de Ferranti S, Mozaffarian D. The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. Clin Chem 2008; 54(6): 945-955.
    • (2008) Clin Chem , vol.54 , Issue.6 , pp. 945-955
    • de Ferranti, S.1    Mozaffarian, D.2
  • 55
    • 62649122332 scopus 로고    scopus 로고
    • Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells
    • Sommer G, Kralisch S, Stangl V, et al. Secretory products from human adipocytes stimulate proinflammatory cytokine secretion from human endothelial cells. J Cell Biochem 2009; 106(4): 729-737.
    • (2009) J Cell Biochem , vol.106 , Issue.4 , pp. 729-737
    • Sommer, G.1    Kralisch, S.2    Stangl, V.3
  • 56
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha
    • Suganami T, Nishida J, Ogawa Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol 2005; 25(10): 2062-2068.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.10 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 57
    • 84932199132 scopus 로고    scopus 로고
    • Adipokines in health and disease
    • Fasshauer M, Blüher M. Adipokines in health and disease. Trends Pharmacol Sci 2015; 36(7): 461-470.
    • (2015) Trends Pharmacol Sci , vol.36 , Issue.7 , pp. 461-470
    • Fasshauer, M.1    Blüher, M.2
  • 58
    • 84870273698 scopus 로고    scopus 로고
    • Clinical relevance of adipokines
    • Blüher M. Clinical relevance of adipokines. Diabetes Metab J 2012; 36(5): 317-327
    • (2012) Diabetes Metab J , vol.36 , Issue.5 , pp. 317-327
    • Blüher, M.1
  • 59
    • 29244476240 scopus 로고    scopus 로고
    • Adipocytokines: leptin--the classical, resistin--the controversical, adiponectin--the promising, and more to come
    • Koerner A, Kratzsch J, Kiess W. Adipocytokines: leptin--the classical, resistin--the controversical, adiponectin--the promising, and more to come. Best Pract Res Clin Endocrinol Metab 2005; 19(4): 525-546.
    • (2005) Best Pract Res Clin Endocrinol Metab , vol.19 , Issue.4 , pp. 525-546
    • Koerner, A.1    Kratzsch, J.2    Kiess, W.3
  • 60
    • 84952983645 scopus 로고    scopus 로고
    • The complex immunological and inflammatory network of adipose tissue in obesity
    • Mol Nutr Food Res 2015
    • Apostolopoulos V, de Courten MP, Stojanovska L, et al. The complex immunological and inflammatory network of adipose tissue in obesity. Mol Nutr Food Res 2015; doi: 10.1002/mnfr.201500272
    • Apostolopoulos, V.1    de Courten, M.P.2    Stojanovska, L.3
  • 61
    • 84939776519 scopus 로고    scopus 로고
    • Adipokines influence the inflammatory balance in autoimmunity
    • Hutcheson J. Adipokines influence the inflammatory balance in autoimmunity. Cytokine 2015; 75(2): 272-279.
    • (2015) Cytokine , vol.75 , Issue.2 , pp. 272-279
    • Hutcheson, J.1
  • 62
    • 84924865586 scopus 로고    scopus 로고
    • The pathophysiology of abdominal adipose tissue depots in health and disease
    • Walker GE, Marzullo P, Ricotti R, et al. The pathophysiology of abdominal adipose tissue depots in health and disease. Horm Mol Biol Clin Investig 2014; 19(1): 57-74.
    • (2014) Horm Mol Biol Clin Investig , vol.19 , Issue.1 , pp. 57-74
    • Walker, G.E.1    Marzullo, P.2    Ricotti, R.3
  • 63
    • 84937423157 scopus 로고    scopus 로고
    • Molecular insights into the role of white adipose tissue in metabolically unhealthy normal weight and metabolically healthy obese individuals
    • Badoud F, Perreault M, Zulyniak MA, Mutch DM. Molecular insights into the role of white adipose tissue in metabolically unhealthy normal weight and metabolically healthy obese individuals. FASEB J 2015; 29(3): 748-758.
    • (2015) FASEB J , vol.29 , Issue.3 , pp. 748-758
    • Badoud, F.1    Perreault, M.2    Zulyniak, M.A.3    Mutch, D.M.4
  • 64
    • 84904730042 scopus 로고    scopus 로고
    • Adipose tissue immune response: novel triggers and consequences for chronic inflammatory conditions
    • Ghigliotti G, Barisione C, Garibaldi S, et al. Adipose tissue immune response: novel triggers and consequences for chronic inflammatory conditions. Inflammation 2014; 37(4): 1337-1353.
    • (2014) Inflammation , vol.37 , Issue.4 , pp. 1337-1353
    • Ghigliotti, G.1    Barisione, C.2    Garibaldi, S.3
  • 66
    • 84957843458 scopus 로고    scopus 로고
    • Differential effects of leptin on adiponectin expression with weight gain versus obesity
    • Singh P, Sharma P, Sahakyan KR, et al. Differential effects of leptin on adiponectin expression with weight gain versus obesity. Int J Obes (Lond) 2015; doi: 10.1038/ijo.2015.181.
    • (2015) Int J Obes (Lond)
    • Singh, P.1    Sharma, P.2    Sahakyan, K.R.3
  • 67
    • 60349110068 scopus 로고    scopus 로고
    • Adiponectin, an unlocking adipocytokine
    • Sun Y, Xun K, Wang C, et al. Adiponectin, an unlocking adipocytokine. Cardiovasc Ther 2009; 27(1): 59-75.
    • (2009) Cardiovasc Ther , vol.27 , Issue.1 , pp. 59-75
    • Sun, Y.1    Xun, K.2    Wang, C.3
  • 68
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • Kadowaki T, Yamauchi T, Kubota N, et al. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 2006; 116(7): 1784-1792.
    • (2006) J Clin Invest , vol.116 , Issue.7 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3
  • 69
    • 84866133825 scopus 로고    scopus 로고
    • Adiponectin: mechanistic insights and clinical implications
    • Turer AT, Scherer PE. Adiponectin: mechanistic insights and clinical implications. Diabetologia 2012; 55(9): 2319-2326.
    • (2012) Diabetologia , vol.55 , Issue.9 , pp. 2319-2326
    • Turer, A.T.1    Scherer, P.E.2
  • 70
    • 84904792209 scopus 로고    scopus 로고
    • New insight into adiponectin role in obesity and obesity-related diseases
    • Nigro E, Scudiero O, Monaco ML, et al. New insight into adiponectin role in obesity and obesity-related diseases. Biomed Res Int 2014; 2014:658913.
    • (2014) Biomed Res Int , vol.2014 , pp. 658913
    • Nigro, E.1    Scudiero, O.2    Monaco, M.L.3
  • 71
    • 84939430528 scopus 로고    scopus 로고
    • Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort
    • Riestra P, Gebreab SY, Xu R, et al. Gender-specific associations between ADIPOQ gene polymorphisms and adiponectin levels and obesity in the Jackson Heart Study cohort. BMC Med Genet 2015; 16(1): 65. doi: 10.1186/s12881-015-0214-x
    • (2015) BMC Med Genet , vol.16 , Issue.1 , pp. 65
    • Riestra, P.1    Gebreab, S.Y.2    Xu, R.3
  • 72
    • 84933512408 scopus 로고    scopus 로고
    • Association between the level of circulating adiponectin and prediabetes: A meta-analysis
    • Lai H, Lin N, Xing Z, Weng H, Zhang H. Association between the level of circulating adiponectin and prediabetes: A meta-analysis. J Diabetes Investig 2015; 6(4): 416-429.
    • (2015) J Diabetes Investig , vol.6 , Issue.4 , pp. 416-429
    • Lai, H.1    Lin, N.2    Xing, Z.3    Weng, H.4    Zhang, H.5
  • 73
    • 85047686974 scopus 로고    scopus 로고
    • Clinical use of adiponectin as a marker of metabolic dysregulation
    • Mather KJ, Goldberg RB. Clinical use of adiponectin as a marker of metabolic dysregulation. Best Pract Res Clin Endocrinol Metab 2014; 28(1): 107-117.
    • (2014) Best Pract Res Clin Endocrinol Metab , vol.28 , Issue.1 , pp. 107-117
    • Mather, K.J.1    Goldberg, R.B.2
  • 75
    • 80054987663 scopus 로고    scopus 로고
    • Portal vein and systemic adiponectin concentrations are closely linked with hepatic glucose and lipoprotein kinetics in extremely obese subjects
    • Magkos F, Fabbrini E, Patterson BW, Eagon JC, Klein S. Portal vein and systemic adiponectin concentrations are closely linked with hepatic glucose and lipoprotein kinetics in extremely obese subjects. Metabolism 2011; 60(11): 1641-1648.
    • (2011) Metabolism , vol.60 , Issue.11 , pp. 1641-1648
    • Magkos, F.1    Fabbrini, E.2    Patterson, B.W.3    Eagon, J.C.4    Klein, S.5
  • 76
    • 84936863972 scopus 로고    scopus 로고
    • Impact of Weight Loss on Plasma Leptin and Adiponectin in Overweight-to-Obese Post Menopausal Breast Cancer Survivors
    • Thompson HJ, Sedlacek SM, Wolfe P, et al. Impact of Weight Loss on Plasma Leptin and Adiponectin in Overweight-to-Obese Post Menopausal Breast Cancer Survivors. Nutrients 2015; 7(7): 5156-5176.
    • (2015) Nutrients , vol.7 , Issue.7 , pp. 5156-5176
    • Thompson, H.J.1    Sedlacek, S.M.2    Wolfe, P.3
  • 77
    • 84938067255 scopus 로고    scopus 로고
    • A Prospective Analysis of Plasma Adiponectin and Risk of Incident Cancer: The Dallas Heart Study
    • Beg MS, Saleem S, Turer A, et al. A Prospective Analysis of Plasma Adiponectin and Risk of Incident Cancer: The Dallas Heart Study. J Natl Compr Canc Netw 2015; 13(7):873-878.
    • (2015) J Natl Compr Canc Netw , vol.13 , Issue.7 , pp. 873-878
    • Beg, M.S.1    Saleem, S.2    Turer, A.3
  • 78
    • 84934275177 scopus 로고    scopus 로고
    • Cross-Talk between Adiponectin and IGF-IR in Breast Cancer
    • Mauro L, Naimo GD, Ricchio E, et al. Cross-Talk between Adiponectin and IGF-IR in Breast Cancer. Front Oncol 2015; 5: 157.
    • (2015) Front Oncol , vol.5 , pp. 157
    • Mauro, L.1    Naimo, G.D.2    Ricchio, E.3
  • 79
    • 84888305648 scopus 로고    scopus 로고
    • Role of adipokines and cytokines in obesity-associated breast cancer: therapeutic targets
    • Khan S, Shukla S, Sinha S, Meeran SM. Role of adipokines and cytokines in obesity-associated breast cancer: therapeutic targets. Cytokine Growth Factor Rev 2013; 24(6): 503-513.
    • (2013) Cytokine Growth Factor Rev , vol.24 , Issue.6 , pp. 503-513
    • Khan, S.1    Shukla, S.2    Sinha, S.3    Meeran, S.M.4
  • 80
    • 84875926584 scopus 로고    scopus 로고
    • Adiponectin affects lung epithelial A549 cell viability counteracting TNFa and IL-1ß toxicity through AdipoR1
    • Nigro E, Scudiero O, Sarnataro D, et al. Adiponectin affects lung epithelial A549 cell viability counteracting TNFa and IL-1ß toxicity through AdipoR1. Int J Biochem Cell Biol 2013; 45(6): 1145-1153.
    • (2013) Int J Biochem Cell Biol , vol.45 , Issue.6 , pp. 1145-1153
    • Nigro, E.1    Scudiero, O.2    Sarnataro, D.3
  • 81
    • 56549085580 scopus 로고    scopus 로고
    • Growth-inhibitory effect of adiponectin via adiponectin receptor 1 on human breast cancer cells through inhibition of S-phase entry without inducing apoptosis
    • Nakayama S, Miyoshi Y, Ishihara H, Noguchi S. Growth-inhibitory effect of adiponectin via adiponectin receptor 1 on human breast cancer cells through inhibition of S-phase entry without inducing apoptosis. Breast Cancer Res Treat 2008; 112(3): 405-410.
    • (2008) Breast Cancer Res Treat , vol.112 , Issue.3 , pp. 405-410
    • Nakayama, S.1    Miyoshi, Y.2    Ishihara, H.3    Noguchi, S.4
  • 82
    • 33947520304 scopus 로고    scopus 로고
    • Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies
    • Körner A, Pazaitou-Panayiotou K, Kelesidis T, et al. Total and high-molecular-weight adiponectin in breast cancer: in vitro and in vivo studies. J Clin Endocrinol Metab 2007; 92(3): 1041-1048.
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.3 , pp. 1041-1048
    • Körner, A.1    Pazaitou-Panayiotou, K.2    Kelesidis, T.3
  • 83
    • 30544453791 scopus 로고    scopus 로고
    • Adiponectin as a growth inhibitor in prostate cancer cells
    • Bub JD, Miyazaki T, Iwamoto Y. Adiponectin as a growth inhibitor in prostate cancer cells. Biochem Biophys Res Commun 2006; 340(4): 1158-1166.
    • (2006) Biochem Biophys Res Commun , vol.340 , Issue.4 , pp. 1158-1166
    • Bub, J.D.1    Miyazaki, T.2    Iwamoto, Y.3
  • 84
    • 84871721695 scopus 로고    scopus 로고
    • Hypoadiponectinemia: a useful marker of dyslipidemia in women with polycystic ovary syndrome
    • Chang CY, Chen MJ, Yang WS, et al. Hypoadiponectinemia: a useful marker of dyslipidemia in women with polycystic ovary syndrome. Taiwan J Obstet Gynecol 2012; 51(4): 583-590.
    • (2012) Taiwan J Obstet Gynecol , vol.51 , Issue.4 , pp. 583-590
    • Chang, C.Y.1    Chen, M.J.2    Yang, W.S.3
  • 85
    • 84873698010 scopus 로고    scopus 로고
    • Decreased adiponectin level is associated with aggressive phenotype of tongue squamous cell carcinoma
    • Guo XH, Wang JY, Gao Y, et al. Decreased adiponectin level is associated with aggressive phenotype of tongue squamous cell carcinoma. Cancer Sci 2013; 104(2): 206-213.
    • (2013) Cancer Sci , vol.104 , Issue.2 , pp. 206-213
    • Guo, X.H.1    Wang, J.Y.2    Gao, Y.3
  • 86
    • 34548249277 scopus 로고    scopus 로고
    • Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model
    • Kamada Y, Matsumoto H, Tamura S, et al. Hypoadiponectinemia accelerates hepatic tumor formation in a nonalcoholic steatohepatitis mouse model. J Hepatol 2007; 47(4): 556-564.
    • (2007) J Hepatol , vol.47 , Issue.4 , pp. 556-564
    • Kamada, Y.1    Matsumoto, H.2    Tamura, S.3
  • 87
    • 84862805884 scopus 로고    scopus 로고
    • Adiponectin inhibits oxidative stress in human prostate carcinoma cells
    • Lu JP, Hou ZF, Duivenvoorden WC, et al. Adiponectin inhibits oxidative stress in human prostate carcinoma cells. Prostate Cancer Prostatic Dis 2012; 15(1): 28-35.
    • (2012) Prostate Cancer Prostatic Dis , vol.15 , Issue.1 , pp. 28-35
    • Lu, J.P.1    Hou, Z.F.2    Duivenvoorden, W.C.3
  • 88
    • 84875038811 scopus 로고    scopus 로고
    • Breast cancer and obesity: in vitro interferences between adipokines and proangiogenic features and/or antitumor therapies?
    • Dubois V, Delort L, Billard H, et al. Breast cancer and obesity: in vitro interferences between adipokines and proangiogenic features and/or antitumor therapies? PLoS One 2013; 8(3): e58541.
    • (2013) PLoS One , vol.8 , Issue.3 , pp. e58541
    • Dubois, V.1    Delort, L.2    Billard, H.3
  • 89
  • 90
    • 84885783040 scopus 로고    scopus 로고
    • Clinical insights from adiponectin analysis in breast cancer patients reveal its anti-inflammatory properties in non-obese women
    • Panis C, Herrera AC, Aranome AM, et al. Clinical insights from adiponectin analysis in breast cancer patients reveal its anti-inflammatory properties in non-obese women. Mol Cell Endocrinol 2014; 382(1): 190-196.
    • (2014) Mol Cell Endocrinol , vol.382 , Issue.1 , pp. 190-196
    • Panis, C.1    Herrera, A.C.2    Aranome, A.M.3
  • 91
    • 84921794842 scopus 로고    scopus 로고
    • PKA/AMPK signaling in relation to adiponectin's antiproliferative effect on multiple myeloma cells
    • Medina EA, Oberheu K, Polusani SR, et al. PKA/AMPK signaling in relation to adiponectin's antiproliferative effect on multiple myeloma cells. Leukemia 2014; 28(10): 2080-2089.
    • (2014) Leukemia , vol.28 , Issue.10 , pp. 2080-2089
    • Medina, E.A.1    Oberheu, K.2    Polusani, S.R.3
  • 93
    • 84959533044 scopus 로고    scopus 로고
    • The multimerization and secretion of adiponectin are regulated by TNF-alpha
    • He Y, Lu L, Wei X, et al. The multimerization and secretion of adiponectin are regulated by TNF-alpha. Endocrine 2015; DOI 10.1007/s12020-015-0741-4, pp 1-13.
    • (2015) Endocrine , pp. 1-13
    • He, Y.1    Lu, L.2    Wei, X.3
  • 94
    • 84926675511 scopus 로고    scopus 로고
    • Role of adiponectin in obesity related gastrointestinal carcinogenesis
    • Nagaraju GP, Aliya S, Alese OB. Role of adiponectin in obesity related gastrointestinal carcinogenesis. Cytokine Growth Factor Rev 2015; 26(1): 83-93.
    • (2015) Cytokine Growth Factor Rev , vol.26 , Issue.1 , pp. 83-93
    • Nagaraju, G.P.1    Aliya, S.2    Alese, O.B.3
  • 95
    • 84904994042 scopus 로고    scopus 로고
    • Association between chemotherapy and plasma adipokines in patients with colorectal cancer
    • Slomian G, Swietochowska E, Malinowska-Borowska J, et al. Association between chemotherapy and plasma adipokines in patients with colorectal cancer. Pharmacol Rep 2014; 66(5): 902-907.
    • (2014) Pharmacol Rep , vol.66 , Issue.5 , pp. 902-907
    • Slomian, G.1    Swietochowska, E.2    Malinowska-Borowska, J.3
  • 96
    • 84864876198 scopus 로고    scopus 로고
    • Associations between adiponectin and two different cancers: breast and colon
    • Gulcelik MA, Colakoglu K, Dincer H, et al. Associations between adiponectin and two different cancers: breast and colon. Asian Pac J Cancer Prev 2012; 13(1): 395-398.
    • (2012) Asian Pac J Cancer Prev , vol.13 , Issue.1 , pp. 395-398
    • Gulcelik, M.A.1    Colakoglu, K.2    Dincer, H.3
  • 97
    • 84937041576 scopus 로고    scopus 로고
    • Associations of Serum Isoflavone, Adiponectin and Insulin Levels with Risk for Epithelial Ovarian Cancer: Results of a Case-control Study
    • Otokozawa S, Tanaka R, Akasaka H, et al. Associations of Serum Isoflavone, Adiponectin and Insulin Levels with Risk for Epithelial Ovarian Cancer: Results of a Case-control Study. Asian Pac J Cancer Prev 2015; 16(12): 4987-4991.
    • (2015) Asian Pac J Cancer Prev , vol.16 , Issue.12 , pp. 4987-4991
    • Otokozawa, S.1    Tanaka, R.2    Akasaka, H.3
  • 98
    • 84933277645 scopus 로고    scopus 로고
    • Adiponectin mediates antiproliferative and apoptotic responses in endometrial carcinoma by the AdipoRs/AMPK pathway
    • Zhang L, Wen K, Han X, et al. Adiponectin mediates antiproliferative and apoptotic responses in endometrial carcinoma by the AdipoRs/AMPK pathway. Gynecol Oncol 2015; 137(2): 311-320.
    • (2015) Gynecol Oncol , vol.137 , Issue.2 , pp. 311-320
    • Zhang, L.1    Wen, K.2    Han, X.3
  • 99
    • 84913609640 scopus 로고    scopus 로고
    • The role of obesity in oesophageal cancer development
    • Long E, Beales IL. The role of obesity in oesophageal cancer development. Therap Adv Gastroenterol 2014; 7(6): 247-268.
    • (2014) Therap Adv Gastroenterol , vol.7 , Issue.6 , pp. 247-268
    • Long, E.1    Beales, I.L.2
  • 100
    • 84940234193 scopus 로고    scopus 로고
    • The influence of nutritional status and disease on adiponectin and TNF-a levels in colorectal cancer patients
    • Abe Vicente M, Donizetti Silva T, Barão K, et al. The influence of nutritional status and disease on adiponectin and TNF-a levels in colorectal cancer patients. Nutr Hosp 2014; 30(1): 140-146.
    • (2014) Nutr Hosp , vol.30 , Issue.1 , pp. 140-146
    • Abe Vicente, M.1    Donizetti Silva, T.2    Barão, K.3
  • 101
    • 84905020159 scopus 로고    scopus 로고
    • Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1a signaling
    • Huang B, Cheng X, Wang D, et al. Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1a signaling. Oncotarget 2014; 5(13): 4732-4745.
    • (2014) Oncotarget , vol.5 , Issue.13 , pp. 4732-4745
    • Huang, B.1    Cheng, X.2    Wang, D.3
  • 102
    • 84891653835 scopus 로고    scopus 로고
    • Adiponectin and leptin molecular actions and clinical significance in breast cancer
    • Nalabolu MR, Palasamudram K, Jamil K. Adiponectin and leptin molecular actions and clinical significance in breast cancer. Int J Hematol Oncol Stem Cell Res 2014; 8(1): 31-40.
    • (2014) Int J Hematol Oncol Stem Cell Res , vol.8 , Issue.1 , pp. 31-40
    • Nalabolu, M.R.1    Palasamudram, K.2    Jamil, K.3
  • 103
    • 84890095895 scopus 로고    scopus 로고
    • Leptin and adiponectin: emerging therapeutic targets in breast cancer
    • Surmacz E. Leptin and adiponectin: emerging therapeutic targets in breast cancer. J Mammary Gland Biol Neoplasia 2013; 18(3-4): 321-332.
    • (2013) J Mammary Gland Biol Neoplasia , vol.18 , Issue.3-4 , pp. 321-332
    • Surmacz, E.1
  • 104
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM,Halaas JL. Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763-770.
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 105
    • 84923606206 scopus 로고    scopus 로고
    • Structure, production and signaling of leptin
    • Münzberg H, Morrison CD. Structure, production and signaling of leptin. Metabolism 2015; 64(1): 13-23.
    • (2015) Metabolism , vol.64 , Issue.1 , pp. 13-23
    • Münzberg, H.1    Morrison, C.D.2
  • 106
    • 84907874989 scopus 로고    scopus 로고
    • 20 years of leptin: human disorders of leptin action
    • Farooqi IS, O'Rahilly S. 20 years of leptin: human disorders of leptin action. J Endocrinol 2014; 223(1): T63-70.
    • (2014) J Endocrinol , vol.223 , Issue.1 , pp. T63-70
    • Farooqi, I.S.1    O'Rahilly, S.2
  • 107
    • 84907867610 scopus 로고    scopus 로고
    • 20 years of leptin: connecting leptin signaling to biological function
    • Allison MB, Myers MG Jr. 20 years of leptin: connecting leptin signaling to biological function. J Endocrinol 2014; 223(1): T25-35.
    • (2014) J Endocrinol , vol.223 , Issue.1 , pp. T25-35
    • Allison, M.B.1    Myers M.G, Jr.2
  • 108
    • 84944512855 scopus 로고    scopus 로고
    • Leptin resistance in obesity: An epigenetic landscape
    • Crujeiras AB, Carreira MC, Cabia B, et al. Leptin resistance in obesity: An epigenetic landscape. Life Sci 2015; pii: S0024-3205(15)00259-3.
    • (2015) Life Sci , Issue.15
    • Crujeiras, A.B.1    Carreira, M.C.2    Cabia, B.3
  • 109
    • 84923898798 scopus 로고    scopus 로고
    • Leptin resistance and diet-induced obesity: central and peripheral actions of leptin
    • Sáinz N, Barrenetxe J, Moreno-Aliaga MJ, Martínez JA. Leptin resistance and diet-induced obesity: central and peripheral actions of leptin. Metabolism 2015; 64(1): 35-46.
    • (2015) Metabolism , vol.64 , Issue.1 , pp. 35-46
    • Sáinz, N.1    Barrenetxe, J.2    Moreno-Aliaga, M.J.3    Martínez, J.A.4
  • 110
    • 84910006155 scopus 로고    scopus 로고
    • Mechanisms behind the link between obesity and gastrointestinal cancers
    • Tilg H, Moschen AR. Mechanisms behind the link between obesity and gastrointestinal cancers. Best Pract Res Clin Gastroenterol 2014; 28(4): 599-610.
    • (2014) Best Pract Res Clin Gastroenterol , vol.28 , Issue.4 , pp. 599-610
    • Tilg, H.1    Moschen, A.R.2
  • 111
    • 84915773887 scopus 로고    scopus 로고
    • The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression
    • Andò S, Barone I, Giordano C, et al. The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression. Front Oncol 2014; 4:340.
    • (2014) Front Oncol , vol.4 , pp. 340
    • Andò, S.1    Barone, I.2    Giordano, C.3
  • 112
    • 84944511750 scopus 로고    scopus 로고
    • Leptin, adipocytes and breast cancer: Focus on inflammation and anti-tumor immunity
    • Delort L, Rossary A, Farges MC, et al. Leptin, adipocytes and breast cancer: Focus on inflammation and anti-tumor immunity. Life Sci 2015; pii: S0024-3205(15)00232-5.
    • (2015) Life Sci
    • Delort, L.1    Rossary, A.2    Farges, M.C.3
  • 113
    • 77951212492 scopus 로고    scopus 로고
    • Role of the adiponectin leptin ratio in prostate cancer
    • Grossmann ME, Mizuno NK, Bonorden MJ, et al. Role of the adiponectin leptin ratio in prostate cancer. Oncol Res 2009; 18: 269-277.
    • (2009) Oncol Res , vol.18 , pp. 269-277
    • Grossmann, M.E.1    Mizuno, N.K.2    Bonorden, M.J.3
  • 114
    • 76149142449 scopus 로고    scopus 로고
    • Leptin and Adiponectin: new players in the field of tumor cell and leukocyte migration
    • Lang K, Ratke J. Leptin and Adiponectin: new players in the field of tumor cell and leukocyte migration. Cell Commun Signal 2009; 7: 27.
    • (2009) Cell Commun Signal , vol.7 , pp. 27
    • Lang, K.1    Ratke, J.2
  • 115
    • 84891653835 scopus 로고    scopus 로고
    • Adiponectin and leptin molecular actions and clinical significance in breast cancer
    • Nalabolu MR, Palasamudram K, Jamil K. Adiponectin and leptin molecular actions and clinical significance in breast cancer. Int J Hematol Oncol Stem Cell Res 2014; 8(1): 31-40.
    • (2014) Int J Hematol Oncol Stem Cell Res , vol.8 , Issue.1 , pp. 31-40
    • Nalabolu, M.R.1    Palasamudram, K.2    Jamil, K.3
  • 116
    • 33745108419 scopus 로고    scopus 로고
    • Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways
    • Sharma D, Saxena NK, Vertino PM, Anania FA. Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways. Endocr Relat Cancer 2006; 13: 629-640.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 629-640
    • Sharma, D.1    Saxena, N.K.2    Vertino, P.M.3    Anania, F.A.4
  • 117
    • 12244271468 scopus 로고    scopus 로고
    • Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells
    • Choi JH, Park SH, Leung PC, Choi KC. Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells. J Clin Endocrinol Metab 2005; 90: 207-210.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 207-210
    • Choi, J.H.1    Park, S.H.2    Leung, P.C.3    Choi, K.C.4
  • 118
    • 77951918926 scopus 로고    scopus 로고
    • Macrophages, inflammation, and insulin resistance
    • Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol 2010; 72: 219-246.
    • (2010) Annu Rev Physiol , vol.72 , pp. 219-246
    • Olefsky, J.M.1    Glass, C.K.2
  • 119
    • 84928649587 scopus 로고    scopus 로고
    • Adipose tissue, obesity and adipokines: role in cancer promotion
    • Booth A, Magnuson A, Fouts J, Foster M. Adipose tissue, obesity and adipokines: role in cancer promotion. Horm Mol Biol Clin Investig 2015; 21(1): 57-74.
    • (2015) Horm Mol Biol Clin Investig , vol.21 , Issue.1 , pp. 57-74
    • Booth, A.1    Magnuson, A.2    Fouts, J.3    Foster, M.4
  • 120
    • 84900394642 scopus 로고    scopus 로고
    • Obesity and colorectal cancer: role of adipokines in tumor initiation and progression
    • Riondino S, Roselli M, Palmirotta R, et al. Obesity and colorectal cancer: role of adipokines in tumor initiation and progression. World J Gastroenterol 2014; 20(18): 5177-5190.
    • (2014) World J Gastroenterol , vol.20 , Issue.18 , pp. 5177-5190
    • Riondino, S.1    Roselli, M.2    Palmirotta, R.3
  • 121
    • 84885392560 scopus 로고    scopus 로고
    • Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer
    • Howe LR, Subbaramaiah K, Hudis CA, Dannenberg AJ. Molecular pathways: adipose inflammation as a mediator of obesity-associated cancer. Clin Cancer Res 2013; 19(22): 6074-6083.
    • (2013) Clin Cancer Res , vol.19 , Issue.22 , pp. 6074-6083
    • Howe, L.R.1    Subbaramaiah, K.2    Hudis, C.A.3    Dannenberg, A.J.4
  • 123
    • 84921345437 scopus 로고    scopus 로고
    • Obesity and cancer: local and systemic mechanisms
    • Iyengar NM, Hudis CA, Dannenberg AJ. Obesity and cancer: local and systemic mechanisms. Annu Rev Med 2015; 66: 297-309.
    • (2015) Annu Rev Med , vol.66 , pp. 297-309
    • Iyengar, N.M.1    Hudis, C.A.2    Dannenberg, A.J.3
  • 124
    • 84892645010 scopus 로고    scopus 로고
    • Interacting inflammatory and growth factor signals underlie the obesity-cancer link
    • Lashinger LM, Ford NA, Hursting SD. Interacting inflammatory and growth factor signals underlie the obesity-cancer link. J Nutr 2014; 144(2): 109-113.
    • (2014) J Nutr , vol.144 , Issue.2 , pp. 109-113
    • Lashinger, L.M.1    Ford, N.A.2    Hursting, S.D.3
  • 125
    • 70349484670 scopus 로고    scopus 로고
    • Mechanisms of obesity and related pathologies: the macro-and microcirculation of adipose tissue
    • Rutkowski JM, Davis KE, Scherer PE. Mechanisms of obesity and related pathologies: the macro-and microcirculation of adipose tissue. FEBS J 2009; 276(20): 5738-5746.
    • (2009) FEBS J , vol.276 , Issue.20 , pp. 5738-5746
    • Rutkowski, J.M.1    Davis, K.E.2    Scherer, P.E.3
  • 126
    • 84877349617 scopus 로고    scopus 로고
    • Common mechanisms of dysfunctional adipose tissue and obesity-related cancers
    • Matafome P, Santos-Silva D, Sena CM, Seiça R. Common mechanisms of dysfunctional adipose tissue and obesity-related cancers. Diabetes Metab Res Rev 2013; 29(4):285-295.
    • (2013) Diabetes Metab Res Rev , vol.29 , Issue.4 , pp. 285-295
    • Matafome, P.1    Santos-Silva, D.2    Sena, C.M.3    Seiça, R.4
  • 127
    • 84952983645 scopus 로고    scopus 로고
    • The complex immunological and inflammatory network of adipose tissue in obesity
    • Apostolopoulos V, de Courten MP, Stojanovska L, et al. The complex immunological and inflammatory network of adipose tissue in obesity. Mol Nutr Food Res 2015; doi: 10.1002/mnfr.201500272.
    • (2015) Mol Nutr Food Res
    • Apostolopoulos, V.1    de Courten, M.P.2    Stojanovska, L.3
  • 128
    • 84940953781 scopus 로고    scopus 로고
    • The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation
    • Wensveen FM, Valentic S, Šestan M, et al. The "Big Bang" in obese fat: Events initiating obesity-induced adipose tissue inflammation. Eur J Immunol 2015; 45(9): 2446-2456. doi: 10.1002/eji.201545502.
    • (2015) Eur J Immunol , vol.45 , Issue.9 , pp. 2446-2456
    • Wensveen, F.M.1    Valentic, S.2    Šestan, M.3
  • 129
    • 84893663418 scopus 로고    scopus 로고
    • Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance
    • Lee BC, Lee J. Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance. Biochim Biophys Acta 2014; 1842(3): 446-462.
    • (2014) Biochim Biophys Acta , vol.1842 , Issue.3 , pp. 446-462
    • Lee, B.C.1    Lee, J.2
  • 130
    • 84901424065 scopus 로고    scopus 로고
    • Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity
    • Huh JY, Park YJ, Ham M, Kim JB. Crosstalk between adipocytes and immune cells in adipose tissue inflammation and metabolic dysregulation in obesity. Mol Cells 2014; 37(5): 365-371.
    • (2014) Mol Cells , vol.37 , Issue.5 , pp. 365-371
    • Huh, J.Y.1    Park, Y.J.2    Ham, M.3    Kim, J.B.4
  • 131
    • 84911891418 scopus 로고    scopus 로고
    • Immune cell crosstalk in obesity: a key role for costimulation?
    • Seijkens T, Kusters P, Chatzigeorgiou A, et al. Immune cell crosstalk in obesity: a key role for costimulation? Diabetes 2014; 63(12): 3982-3991.
    • (2014) Diabetes , vol.63 , Issue.12 , pp. 3982-3991
    • Seijkens, T.1    Kusters, P.2    Chatzigeorgiou, A.3
  • 132
    • 84904722547 scopus 로고    scopus 로고
    • Obesity and cancer-mechanisms underlying tumour progression and recurrence
    • Park J, Morley TS, Kim M, et al. Obesity and cancer-mechanisms underlying tumour progression and recurrence. Nat Rev Endocrinol 2014; 10(8): 455-465.
    • (2014) Nat Rev Endocrinol , vol.10 , Issue.8 , pp. 455-465
    • Park, J.1    Morley, T.S.2    Kim, M.3
  • 133
    • 84901500556 scopus 로고    scopus 로고
    • The microbiome and obesity-an established risk for certain types of cancer
    • Rogers CJ, Prabhu KS, Vijay-Kumar M. The microbiome and obesity-an established risk for certain types of cancer. Cancer J 2014; 20(3): 176-180.
    • (2014) Cancer J , vol.20 , Issue.3 , pp. 176-180
    • Rogers, C.J.1    Prabhu, K.S.2    Vijay-Kumar, M.3
  • 134
    • 84892645010 scopus 로고    scopus 로고
    • Interacting inflammatory and growth factor signals underlie the obesity-cancer link
    • Lashinger LM, Ford NA, Hursting SD. Interacting inflammatory and growth factor signals underlie the obesity-cancer link. J Nutr 2014; 144(2): 109-113.
    • (2014) J Nutr , vol.144 , Issue.2 , pp. 109-113
    • Lashinger, L.M.1    Ford, N.A.2    Hursting, S.D.3
  • 135
    • 84884221010 scopus 로고    scopus 로고
    • Obesity as a major risk factor for cancer
    • De Pergola G, Silvestris F. Obesity as a major risk factor for cancer. J Obes 2013; 2013:291546.
    • (2013) J Obes , vol.2013 , pp. 291546
    • De Pergola, G.1    Silvestris, F.2
  • 136
    • 33748105839 scopus 로고    scopus 로고
    • The contribution of Rudolf Virchow to the concept of inflammation: what is still of importance?
    • Heidland A, Klassen A, Rutkowski P, Bahner U. The contribution of Rudolf Virchow to the concept of inflammation: what is still of importance? J Nephrol 2006; 19 Suppl 10:S102-S109.
    • (2006) J Nephrol , vol.19 , pp. S102-S109
    • Heidland, A.1    Klassen, A.2    Rutkowski, P.3    Bahner, U.4
  • 137
    • 33746069082 scopus 로고    scopus 로고
    • In memoriam of Rudolf Virchow: a historical retrospective including aspects of inflammation, infection and neoplasia
    • Schmidt A, Weber OF. In memoriam of Rudolf Virchow: a historical retrospective including aspects of inflammation, infection and neoplasia. Contrib Microbiol 2006; 13: 1-15.
    • (2006) Contrib Microbiol , vol.13 , pp. 1-15
    • Schmidt, A.1    Weber, O.F.2
  • 138
    • 84943159909 scopus 로고    scopus 로고
    • Hematopoietic stem cell-derived cancer-associated fibroblasts are novel contributors to the pro-tumorigenic microenvironment
    • McDonald LT, Russell DL, Kelly RR, et al. Hematopoietic stem cell-derived cancer-associated fibroblasts are novel contributors to the pro-tumorigenic microenvironment. Neoplasia 2015; 17(5):434-48.
    • (2015) Neoplasia , vol.17 , Issue.5 , pp. 434-448
    • McDonald, L.T.1    Russell, D.L.2    Kelly, R.R.3
  • 139
    • 84875908512 scopus 로고    scopus 로고
    • Adipocytes as a critical component of the tumor microenvironment
    • Vona-Davis L, Gibson LF. Adipocytes as a critical component of the tumor microenvironment. Leuk Res 2013; 37(5): 483-484.
    • (2013) Leuk Res , vol.37 , Issue.5 , pp. 483-484
    • Vona-Davis, L.1    Gibson, L.F.2
  • 140
    • 0034880752 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and adipose tissue
    • Proc Nutr Soc 2001 Aug
    • Coppack SW. Pro-inflammatory cytokines and adipose tissue. Proc Nutr Soc 2001 Aug; 60(3): 349-56.
    • , vol.60 , Issue.3 , pp. 349-356
    • Coppack, S.W.1
  • 141
    • 33846201363 scopus 로고    scopus 로고
    • Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells
    • Fain JN. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm 2006; 74: 443-477.
    • (2006) Vitam Horm , vol.74 , pp. 443-477
    • Fain, J.N.1
  • 142
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: inflammation and the pleiotropic role of white adipose tissue
    • Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004; 92(3): 347-55.
    • (2004) Br J Nutr , vol.92 , Issue.3 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 143
    • 54349124582 scopus 로고    scopus 로고
    • Hypoxia and the endocrine and signalling role of white adipose tissue
    • Trayhurn P, Wang B, Wood IS. Hypoxia and the endocrine and signalling role of white adipose tissue. Arch Physiol Biochem 2008; 114(4): 267-276.
    • (2008) Arch Physiol Biochem , vol.114 , Issue.4 , pp. 267-276
    • Trayhurn, P.1    Wang, B.2    Wood, I.S.3
  • 145
    • 55149097289 scopus 로고    scopus 로고
    • Tumor necrosis factor and cancer, buddies or foes?
    • Wang X, Lin Y. Tumor necrosis factor and cancer, buddies or foes? Acta Pharmacologica Sinica 2008; 29(11): 1275-1288.
    • (2008) Acta Pharmacologica Sinica , vol.29 , Issue.11 , pp. 1275-1288
    • Wang, X.1    Lin, Y.2
  • 147
    • 77956646676 scopus 로고    scopus 로고
    • Elevated expression of tumor necrosis factor-alpha signaling molecules in colonic tumors of Zucker obese (fa/fa) rats
    • Jain SS, Bird RP. Elevated expression of tumor necrosis factor-alpha signaling molecules in colonic tumors of Zucker obese (fa/fa) rats. Int J Cancer 2010; 127: 2042-2050.
    • (2010) Int J Cancer , vol.127 , pp. 2042-2050
    • Jain, S.S.1    Bird, R.P.2
  • 148
    • 84876009557 scopus 로고    scopus 로고
    • Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-a, Caspase-8, Caspase-3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro
    • Chen YL, Yan MY, Chien SY, et al. Sann-Joong-Kuey-Jian-Tang inhibits hepatocellular carcinoma Hep-G2 cell proliferation by increasing TNF-a, Caspase-8, Caspase-3 and Bax but by decreasing TCTP and Mcl-1 expression in vitro. Mol Med Rep 2013; 7(5): 1487-1493.
    • (2013) Mol Med Rep , vol.7 , Issue.5 , pp. 1487-1493
    • Chen, Y.L.1    Yan, M.Y.2    Chien, S.Y.3
  • 149
    • 53649108526 scopus 로고    scopus 로고
    • Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon
    • Lukasiak S, Schiller C, Oehlschlaeger P, et al. Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon. Oncogene 2008; 27(46): 6068-6074.
    • (2008) Oncogene , vol.27 , Issue.46 , pp. 6068-6074
    • Lukasiak, S.1    Schiller, C.2    Oehlschlaeger, P.3
  • 150
    • 84904670754 scopus 로고    scopus 로고
    • Putative role of adipose tissue in growth and metabolism of colon cancer cells
    • Schwartz B, Yehuda-Shnaidman E. Putative role of adipose tissue in growth and metabolism of colon cancer cells. Front Oncol 2014; 4:164.
    • (2014) Front Oncol , vol.4 , pp. 164
    • Schwartz, B.1    Yehuda-Shnaidman, E.2
  • 152
    • 0035023128 scopus 로고    scopus 로고
    • Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance
    • Kern PA, Ranganathan S, Li C, et al. Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance. Am J Physiol Endocrinol Metab 2001; 280: E745-751.
    • (2001) Am J Physiol Endocrinol Metab , vol.280 , pp. E745-751
    • Kern, P.A.1    Ranganathan, S.2    Li, C.3
  • 154
    • 20444480549 scopus 로고    scopus 로고
    • Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-a and IL-6
    • Park HS, Park JY, Yu R. Relationship of obesity and visceral adiposity with serum concentrations of CRP, TNF-a and IL-6. Diabetes Research and Clinical Practice 2005; 69(1): 29-35.
    • (2005) Diabetes Research and Clinical Practice , vol.69 , Issue.1 , pp. 29-35
    • Park, H.S.1    Park, J.Y.2    Yu, R.3
  • 155
    • 0037123348 scopus 로고    scopus 로고
    • Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells
    • Syed V, Ulinski G, Mok SC, Ho SM. Reproductive hormone-induced, STAT3-mediated interleukin 6 action in normal and malignant human ovarian surface epithelial cells. Journal of the National Cancer Institute 2002; 94(8): 617-629.
    • (2002) Journal of the National Cancer Institute , vol.94 , Issue.8 , pp. 617-629
    • Syed, V.1    Ulinski, G.2    Mok, S.C.3    Ho, S.M.4
  • 156
    • 0038581774 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system
    • Sriuranpong V, Park JI, Amornphimoltham P, et al. Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system. Cancer Research 2003; 63(11): 2948-2956.
    • (2003) Cancer Research , vol.63 , Issue.11 , pp. 2948-2956
    • Sriuranpong, V.1    Park, J.I.2    Amornphimoltham, P.3
  • 157
    • 0035180451 scopus 로고    scopus 로고
    • Interleukin-6 is an autocrine growth factor in human prostate cancer
    • Giri D, Ozen M, Ittmann M. Interleukin-6 is an autocrine growth factor in human prostate cancer. American Journal of Pathology 2001; 159(6): 2159-2165.
    • (2001) American Journal of Pathology , vol.159 , Issue.6 , pp. 2159-2165
    • Giri, D.1    Ozen, M.2    Ittmann, M.3
  • 158
    • 61549142050 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) released by macrophages induces IL-6 secretion in the human colon cancer HT-29 cell line
    • Li YY, Hsieh LL, Tang RP, et al. Interleukin-6 (IL-6) released by macrophages induces IL-6 secretion in the human colon cancer HT-29 cell line. Human Immunology 2009; 70(3): 151-158.
    • (2009) Human Immunology , vol.70 , Issue.3 , pp. 151-158
    • Li, Y.Y.1    Hsieh, L.L.2    Tang, R.P.3
  • 159
    • 84908243244 scopus 로고    scopus 로고
    • Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer
    • Pei BX, Sun BS, Zhang ZF, et al. Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer. J Thorac Cardiovasc Surg 2014; 148(4): 1208-1216.e2.
    • (2014) J Thorac Cardiovasc Surg , vol.148 , Issue.4 , pp. 1208-1216.e2
    • Pei, B.X.1    Sun, B.S.2    Zhang, Z.F.3
  • 160
    • 84925335444 scopus 로고    scopus 로고
    • Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer
    • Chen ZY, Raghav K, Lieu CH, et al. Cytokine profile and prognostic significance of high neutrophil-lymphocyte ratio in colorectal cancer. Br J Cancer 2015; 112(6): 1088-1097.
    • (2015) Br J Cancer , vol.112 , Issue.6 , pp. 1088-1097
    • Chen, Z.Y.1    Raghav, K.2    Lieu, C.H.3
  • 161
    • 84893156426 scopus 로고    scopus 로고
    • Coexpression of IL-6 and TNF-a: prognostic significance on breast cancer outcome
    • Tripsianis G, Papadopoulou E, Anagnostopoulos K, et al. Coexpression of IL-6 and TNF-a: prognostic significance on breast cancer outcome. Neoplasma 2014; 61(2): 205-212.
    • (2014) Neoplasma , vol.61 , Issue.2 , pp. 205-212
    • Tripsianis, G.1    Papadopoulou, E.2    Anagnostopoulos, K.3
  • 162
    • 84880886185 scopus 로고    scopus 로고
    • Salivary levels of TNF-a and IL-6 in patients with oral premalignant and malignant lesions
    • Juretic M, Cerovic R, Belušic-Gobic M, et al. Salivary levels of TNF-a and IL-6 in patients with oral premalignant and malignant lesions. Folia Biol (Praha) 2013; 59(2): 99-102.
    • (2013) Folia Biol (Praha) , vol.59 , Issue.2 , pp. 99-102
    • Juretic, M.1    Cerovic, R.2    Belušic-Gobic, M.3
  • 163
    • 0034742512 scopus 로고    scopus 로고
    • IL (interleukin)-1 alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas
    • Wolf JS, Chen Z, Dong G, et al. IL (interleukin)-1 alpha promotes nuclear factor-kappaB and AP-1-induced IL-8 expression, cell survival, and proliferation in head and neck squamous cell carcinomas. Clin Cancer Res 2001; 7(6): 1812-1820.
    • (2001) Clin Cancer Res , vol.7 , Issue.6 , pp. 1812-1820
    • Wolf, J.S.1    Chen, Z.2    Dong, G.3
  • 164
    • 0347334750 scopus 로고    scopus 로고
    • IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis
    • Jung YJ, Isaacs JS, Lee S, et al. IL-1beta-mediated up-regulation of HIF-1alpha via an NFkappaB/COX-2 pathway identifies HIF-1 as a critical link between inflammation and oncogenesis. FASEB J 2003; 17(14): 2115-2117.
    • (2003) FASEB J , vol.17 , Issue.14 , pp. 2115-2117
    • Jung, Y.J.1    Isaacs, J.S.2    Lee, S.3
  • 165
    • 80053130721 scopus 로고    scopus 로고
    • Adipose tissue dysfunction and hypertriglyceridemia: mechanisms and management
    • van de Woestijne AP, Monajemi H, Kalkhoven E, Visseren FL. Adipose tissue dysfunction and hypertriglyceridemia: mechanisms and management. Obes Rev 2011; 12(10): 829-840.
    • (2011) Obes Rev , vol.12 , Issue.10 , pp. 829-840
    • van de Woestijne, A.P.1    Monajemi, H.2    Kalkhoven, E.3    Visseren, F.L.4
  • 166
    • 0034880752 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and adipose tissue
    • Coppack SW. Pro-inflammatory cytokines and adipose tissue. Proc Nutr Soc 2001; 60(3): 349-356.
    • (2001) Proc Nutr Soc , vol.60 , Issue.3 , pp. 349-356
    • Coppack, S.W.1
  • 167
    • 70449498069 scopus 로고    scopus 로고
    • Lipid modification in type 2 diabetes: the role of LDL and HDL
    • Vergès B. Lipid modification in type 2 diabetes: the role of LDL and HDL. Fundam Clin Pharmacol 2009; 23(6): 681-685.
    • (2009) Fundam Clin Pharmacol , vol.23 , Issue.6 , pp. 681-685
    • Vergès, B.1
  • 168
    • 84878019587 scopus 로고    scopus 로고
    • Gluten-free diet reduces adiposity, inflammation and insulin resistance associated with the induction of PPAR-alpha and PPAR-gamma expression
    • Soares FL, de Oliveira Matoso R, Teixeira LG, et al. Gluten-free diet reduces adiposity, inflammation and insulin resistance associated with the induction of PPAR-alpha and PPAR-gamma expression. J Nutr Biochem 2013; 24(6): 1105-1111.
    • (2013) J Nutr Biochem , vol.24 , Issue.6 , pp. 1105-1111
    • Soares, F.L.1    de Oliveira Matoso, R.2    Teixeira, L.G.3
  • 169
    • 40749100682 scopus 로고    scopus 로고
    • In vivo arterial lipoprotein lipase expression augments inflammatory responses and impairs vascular dilatation
    • Takahashi M, Hiyama Y, Yokoyama M, et al. In vivo arterial lipoprotein lipase expression augments inflammatory responses and impairs vascular dilatation. Arterioscler Thromb Vasc Biol 2008; 28(3): 455-462.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.3 , pp. 455-462
    • Takahashi, M.1    Hiyama, Y.2    Yokoyama, M.3
  • 170
    • 64749100482 scopus 로고    scopus 로고
    • Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation
    • Wang L, Gill R, Pedersen TL, et al. Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation. J Lipid Res 2009; 50(2): 204-213.
    • (2009) J Lipid Res , vol.50 , Issue.2 , pp. 204-213
    • Wang, L.1    Gill, R.2    Pedersen, T.L.3
  • 171
    • 0036138579 scopus 로고    scopus 로고
    • Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study
    • Goodwin PJ, Ennis M, Pritchard KI, et al. Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study. J Clin Oncol 2002; 20: 42-51.
    • (2002) J Clin Oncol , vol.20 , pp. 42-51
    • Goodwin, P.J.1    Ennis, M.2    Pritchard, K.I.3
  • 172
    • 54349083481 scopus 로고    scopus 로고
    • Prediagnostic body-mass index, plasma C-peptide concentration and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis
    • Ma J, Li H, Giovannucci E, et al. Prediagnostic body-mass index, plasma C-peptide concentration and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis. Lancet Oncol 2008; 9: 1039-1047.
    • (2008) Lancet Oncol , vol.9 , pp. 1039-1047
    • Ma, J.1    Li, H.2    Giovannucci, E.3
  • 173
    • 58049192725 scopus 로고    scopus 로고
    • Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis
    • Barone BB, Yeh HC, Snyder CF, et al. Long-term all-cause mortality in cancer patients with preexisting diabetes mellitus: a systematic review and meta-analysis. JAMA 2008; 300: 2754-2764.
    • (2008) JAMA , vol.300 , pp. 2754-2764
    • Barone, B.B.1    Yeh, H.C.2    Snyder, C.F.3
  • 174
    • 77949329629 scopus 로고    scopus 로고
    • Cellular hypoxia and adipose tissue dysfunction in obesity
    • Wood IS, de Heredia FP, Wang B, Trayhurn P. Cellular hypoxia and adipose tissue dysfunction in obesity. Proc Nutr Soc 2009; 68(4): 370-377.
    • (2009) Proc Nutr Soc , vol.68 , Issue.4 , pp. 370-377
    • Wood, I.S.1    de Heredia, F.P.2    Wang, B.3    Trayhurn, P.4
  • 175
    • 26244448904 scopus 로고    scopus 로고
    • A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha
    • Suganami T, Nishida J, Ogawa Y. A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol 2005; 25(10): 2062-2068.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , Issue.10 , pp. 2062-2068
    • Suganami, T.1    Nishida, J.2    Ogawa, Y.3
  • 176
    • 84941961424 scopus 로고    scopus 로고
    • Adipose Tissue Inflammation in the Pathogenesis of Type2 Diabetes
    • Kohlgruber A, Lynch L. Adipose Tissue Inflammation in the Pathogenesis of Type2 Diabetes. Curr Diab Rep 2015; 15(11): 92.
    • (2015) Curr Diab Rep , vol.15 , Issue.11 , pp. 92
    • Kohlgruber, A.1    Lynch, L.2
  • 177
    • 84943328566 scopus 로고    scopus 로고
    • Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity
    • Subramanian M, Ozcan L, Ghorpade DS, et al. Suppression of Adaptive Immune Cell Activation Does Not Alter Innate Immune Adipose Inflammation or Insulin Resistance in Obesity. PLoS One 2015; 10(8):e0135842.
    • (2015) PLoS One , vol.10 , Issue.8 , pp. e0135842
    • Subramanian, M.1    Ozcan, L.2    Ghorpade, D.S.3
  • 178
    • 84983203439 scopus 로고    scopus 로고
    • Inflammation-induced microvascular insulin resistance is an early event in diet-induced obesity
    • Zhao L, Fu Z, Wu J, et al. Inflammation-induced microvascular insulin resistance is an early event in diet-induced obesity. Clin Sci (Lond) 2015; 129(12): 1025-1036.
    • (2015) Clin Sci (Lond) , vol.129 , Issue.12 , pp. 1025-1036
    • Zhao, L.1    Fu, Z.2    Wu, J.3
  • 179
    • 84931576188 scopus 로고    scopus 로고
    • A major role of insulin in promoting obesity-associated adipose tissue inflammation
    • Pedersen DJ, Guilherme A, Danai LV et al. A major role of insulin in promoting obesity-associated adipose tissue inflammation. Mol Metab 2015; 4(7): 507-518.
    • (2015) Mol Metab , vol.4 , Issue.7 , pp. 507-518
    • Pedersen, D.J.1    Guilherme, A.2    Danai, L.V3
  • 180
    • 84934343239 scopus 로고    scopus 로고
    • Mechanisms Linking Inflammation to Insulin Resistance
    • Chen L, Chen R, Wang H, Liang F. Mechanisms Linking Inflammation to Insulin Resistance. Int J Endocrinol 2015; 2015:508409. doi: 10.1155/2015/508409.
    • (2015) Int J Endocrinol , vol.2015 , pp. 508409
    • Chen, L.1    Chen, R.2    Wang, H.3    Liang, F.4
  • 181
    • 84879459608 scopus 로고    scopus 로고
    • Inflammation, cytokines and insulin resistance: a clinical perspective
    • Wieser V, Moschen AR, Tilg H. Inflammation, cytokines and insulin resistance: a clinical perspective. Arch Immunol Ther Exp (Warsz) 2013; 61(2): 119-125.
    • (2013) Arch Immunol Ther Exp (Warsz) , vol.61 , Issue.2 , pp. 119-125
    • Wieser, V.1    Moschen, A.R.2    Tilg, H.3
  • 182
    • 84868122221 scopus 로고    scopus 로고
    • Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation
    • Barbarroja N, Lopez-Pedrera C, Garrido-Sanchez L, et al. Progression from high insulin resistance to type 2 diabetes does not entail additional visceral adipose tissue inflammation. PLoS One 2012; 7(10): e48155.
    • (2012) PLoS One , vol.7 , Issue.10 , pp. e48155
    • Barbarroja, N.1    Lopez-Pedrera, C.2    Garrido-Sanchez, L.3
  • 183
    • 77955494890 scopus 로고    scopus 로고
    • The obese healthy paradox: is inflammation the answer?
    • Barbarroja N, López-Pedrera R, Mayas MD, et al. The obese healthy paradox: is inflammation the answer? Biochem J 2010; 430(1): 141-149.
    • (2010) Biochem J , vol.430 , Issue.1 , pp. 141-149
    • Barbarroja, N.1    López-Pedrera, R.2    Mayas, M.D.3
  • 184
    • 84936743673 scopus 로고    scopus 로고
    • Evaluation of miR-29c inhibits endotheliocyte migration and angiogenesis of human endothelial cells by suppressing the insulin like growth factor 1
    • Hu Y, Deng F, Song J, et al. Evaluation of miR-29c inhibits endotheliocyte migration and angiogenesis of human endothelial cells by suppressing the insulin like growth factor 1. Am J Transl Res 2015; 7(5): 866-877.
    • (2015) Am J Transl Res , vol.7 , Issue.5 , pp. 866-877
    • Hu, Y.1    Deng, F.2    Song, J.3
  • 185
    • 84926442274 scopus 로고    scopus 로고
    • Insulin-like growth factor system in cancer: novel targeted therapies
    • Brahmkhatri VP, Prasanna C, Atreya HS. Insulin-like growth factor system in cancer: novel targeted therapies. Biomed Res Int 2015; 2015:538019.
    • (2015) Biomed Res Int , vol.2015 , pp. 538019
    • Brahmkhatri, V.P.1    Prasanna, C.2    Atreya, H.S.3
  • 186
    • 84921787825 scopus 로고    scopus 로고
    • Effect of hypoxia on hypoxia inducible factor-1a, insulin-like growth factor I and vascular endothelial growth factor expression in hepatocellular carcinoma HepG2 cells
    • Liu Q, Xu Z, Mao S, et al. Effect of hypoxia on hypoxia inducible factor-1a, insulin-like growth factor I and vascular endothelial growth factor expression in hepatocellular carcinoma HepG2 cells. Oncol Lett 2015; 9(3): 1142-1148.
    • (2015) Oncol Lett , vol.9 , Issue.3 , pp. 1142-1148
    • Liu, Q.1    Xu, Z.2    Mao, S.3
  • 187
    • 84923068390 scopus 로고    scopus 로고
    • Assessment of insulin-like growth factor 1 receptor as an oncogene in esophageal squamous cell carcinoma and its potential implication in chemotherapy
    • Ma W, Zhang T, Pan J, et al. Assessment of insulin-like growth factor 1 receptor as an oncogene in esophageal squamous cell carcinoma and its potential implication in chemotherapy. Oncol Rep 2014; 32(4): 1601-1609.
    • (2014) Oncol Rep , vol.32 , Issue.4 , pp. 1601-1609
    • Ma, W.1    Zhang, T.2    Pan, J.3
  • 188
    • 77949329629 scopus 로고    scopus 로고
    • Cellular hypoxia and adipose tissue dysfunction in obesity
    • Wood IS, de Heredia FP, Wang B, Trayhurn P. Cellular hypoxia and adipose tissue dysfunction in obesity. Proc Nutr Soc 2009; 68(4): 370-377.
    • (2009) Proc Nutr Soc , vol.68 , Issue.4 , pp. 370-377
    • Wood, I.S.1    de Heredia, F.P.2    Wang, B.3    Trayhurn, P.4
  • 189
    • 47849121225 scopus 로고    scopus 로고
    • Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity?
    • Trayhurn P, Wang B, Wood IS. Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br J Nutr 2008; 100(2): 227-235.
    • (2008) Br J Nutr , vol.100 , Issue.2 , pp. 227-235
    • Trayhurn, P.1    Wang, B.2    Wood, I.S.3
  • 190
    • 84905658394 scopus 로고    scopus 로고
    • Obesity associated hypertension: new insights into mechanism
    • Kang YS. Obesity associated hypertension: new insights into mechanism. Electrolyte Blood Press 2013; 11(2): 46-52.
    • (2013) Electrolyte Blood Press , vol.11 , Issue.2 , pp. 46-52
    • Kang, Y.S.1
  • 191
    • 84893722362 scopus 로고    scopus 로고
    • Adipose tissue and adipocyte dysregulation
    • Lafontan M. Adipose tissue and adipocyte dysregulation. Diabetes Metab 2014; 40(1): 16-28.
    • (2014) Diabetes Metab , vol.40 , Issue.1 , pp. 16-28
    • Lafontan, M.1
  • 192
    • 84875849127 scopus 로고    scopus 로고
    • White and brown adipose stem cells: from signaling to clinical implications
    • Algire C, Medrikova D, Herzig S. White and brown adipose stem cells: from signaling to clinical implications. Biochim Biophys Acta 2013; 1831(5): 896-904.
    • (2013) Biochim Biophys Acta , vol.1831 , Issue.5 , pp. 896-904
    • Algire, C.1    Medrikova, D.2    Herzig, S.3
  • 193
    • 84874118190 scopus 로고    scopus 로고
    • Oxidative stress and lipid peroxidation by-products at the crossroad between adipose organ dysregulation and obesity-linked insulin resistance
    • Murdolo G, Piroddi M, Luchetti F, et al. Oxidative stress and lipid peroxidation by-products at the crossroad between adipose organ dysregulation and obesity-linked insulin resistance. Biochimie 2013; 95(3): 585-594.
    • (2013) Biochimie , vol.95 , Issue.3 , pp. 585-594
    • Murdolo, G.1    Piroddi, M.2    Luchetti, F.3
  • 194
    • 84867743194 scopus 로고    scopus 로고
    • Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype
    • Sansbury BE, Cummins TD, Tang Y, et al. Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype. Circ Res 2012; 111(9): 1176-1189.
    • (2012) Circ Res , vol.111 , Issue.9 , pp. 1176-1189
    • Sansbury, B.E.1    Cummins, T.D.2    Tang, Y.3
  • 195
    • 26844567233 scopus 로고    scopus 로고
    • Cold-induced expression of the VEGF gene in brown adipose tissue is independent of thermogenic oxygen consumption
    • Fredriksson JM, Nikami H, Nedergaard J. Cold-induced expression of the VEGF gene in brown adipose tissue is independent of thermogenic oxygen consumption. FEBS Lett 2005; 579(25): 5680-5684
    • (2005) FEBS Lett , vol.579 , Issue.25 , pp. 5680-5684
    • Fredriksson, J.M.1    Nikami, H.2    Nedergaard, J.3
  • 196
    • 84899755491 scopus 로고    scopus 로고
    • Vascular rarefaction mediates whitening of brown fat in obesity
    • Shimizu I, Aprahamian T, Kikuchi R, et al. Vascular rarefaction mediates whitening of brown fat in obesity. J Clin Invest 2014; 124(5): 2099-2112.
    • (2014) J Clin Invest , vol.124 , Issue.5 , pp. 2099-2112
    • Shimizu, I.1    Aprahamian, T.2    Kikuchi, R.3
  • 197
    • 84937760401 scopus 로고    scopus 로고
    • Hypoxia potentiates tumor necrosis factor-a induced expression of inducible nitric oxide synthase and cyclooxygenase-2 in white and brown adipocytes
    • May 29
    • Bhattacharya I, Domínguez AP, Drägert K, et al. Hypoxia potentiates tumor necrosis factor-a induced expression of inducible nitric oxide synthase and cyclooxygenase-2 in white and brown adipocytes. Biochem Biophys Res Commun. 2015 May 29;461(2):287-92.
    • (2015) Biochem Biophys Res Commun , vol.461 , Issue.2 , pp. 287-292
    • Bhattacharya, I.1    Domínguez, A.P.2    Drägert, K.3
  • 198
    • 84907693957 scopus 로고    scopus 로고
    • Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications
    • Vernochet C, Damilano F, Mourier A, et al. Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications. FASEB J 2014; 28(10): 4408-4419.
    • (2014) FASEB J , vol.28 , Issue.10 , pp. 4408-4419
    • Vernochet, C.1    Damilano, F.2    Mourier, A.3
  • 199
    • 84926672363 scopus 로고    scopus 로고
    • Oxygen deprivation and the cellular response to hypoxia in adipocytes -perspectives on white and brown adipose tissues in obesity
    • eCollection 2015
    • Trayhurn P, Alomar SY. Oxygen deprivation and the cellular response to hypoxia in adipocytes -perspectives on white and brown adipose tissues in obesity. Front Endocrinol (Lausanne) 2015; 6:19. doi: 10.3389/fendo.2015.00019. eCollection 2015.
    • (2015) Front Endocrinol (Lausanne) , vol.6 , pp. 19
    • Trayhurn, P.1    Alomar, S.Y.2
  • 200
    • 84904611773 scopus 로고    scopus 로고
    • Hypoxia and adipocyte physiology: implications for adipose tissue dysfunction in obesity
    • Trayhurn P. Hypoxia and adipocyte physiology: implications for adipose tissue dysfunction in obesity. Annu Rev Nutr 2014; 34: 207-236.
    • (2014) Annu Rev Nutr , vol.34 , pp. 207-236
    • Trayhurn, P.1
  • 201
    • 85012036928 scopus 로고    scopus 로고
    • Hypoxia, Oxidative Stress and Fat
    • Netzer N, Gatterer H, Faulhaber M, et al. Hypoxia, Oxidative Stress and Fat. Biomolecules 2015; 5(2): 1143-1150.
    • (2015) Biomolecules , vol.5 , Issue.2 , pp. 1143-1150
    • Netzer, N.1    Gatterer, H.2    Faulhaber, M.3
  • 202
    • 3042670643 scopus 로고    scopus 로고
    • Oxygen free radicals and the systemic inflammatory response
    • Closa D, Folch-Puy E. Oxygen free radicals and the systemic inflammatory response. IUBMB Life 2004; 56(4): 185-191.
    • (2004) IUBMB Life , vol.56 , Issue.4 , pp. 185-191
    • Closa, D.1    Folch-Puy, E.2
  • 203
    • 84939176172 scopus 로고    scopus 로고
    • MicroRNA-193b Controls Adiponectin Production in Human White Adipose Tissue
    • Belarbi Y, Mejhert N, Lorente-Cebrián S, et al. MicroRNA-193b Controls Adiponectin Production in Human White Adipose Tissue. J Clin Endocrinol Metab 2015; 100(8): E1084-1088.
    • (2015) J Clin Endocrinol Metab , vol.100 , Issue.8 , pp. E1084-1088
    • Belarbi, Y.1    Mejhert, N.2    Lorente-Cebrián, S.3
  • 204
    • 84918791470 scopus 로고    scopus 로고
    • Novel intracellular mediator of adiponectin secretion from adipocytes
    • Omatsu-Kanbe M, Matsuura H. Novel intracellular mediator of adiponectin secretion from adipocytes. J Physiol 2014; 592(Pt 23): 5141.
    • (2014) J Physiol , vol.592 , Issue.23 , pp. 5141
    • Omatsu-Kanbe, M.1    Matsuura, H.2
  • 205
    • 84885190209 scopus 로고    scopus 로고
    • Angiogenesis and vascular functions in modulation of obesity, adipose metabolism, and insulin sensitivity
    • Cao Y. Angiogenesis and vascular functions in modulation of obesity, adipose metabolism, and insulin sensitivity. Cell Metab 2013; 18(4): 478-489.
    • (2013) Cell Metab , vol.18 , Issue.4 , pp. 478-489
    • Cao, Y.1
  • 206
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis 2000; 21(3): 361-370.
    • (2000) Carcinogenesis , vol.21 , Issue.3 , pp. 361-370
    • Marnett, L.J.1
  • 207
    • 77950023207 scopus 로고    scopus 로고
    • Oxidative stress and oxidative damage in carcinogenesis
    • Klaunig JE, Kamendulis LM, Hocevar BA. Oxidative stress and oxidative damage in carcinogenesis. Toxicol Pathol 2010; 38(1): 96-109.
    • (2010) Toxicol Pathol , vol.38 , Issue.1 , pp. 96-109
    • Klaunig, J.E.1    Kamendulis, L.M.2    Hocevar, B.A.3
  • 208
    • 33847281886 scopus 로고    scopus 로고
    • DNA damage, a biomarker of carcinogenesis: its measurement and modulation by diet and environment
    • Hwang ES, Bowen PE. DNA damage, a biomarker of carcinogenesis: its measurement and modulation by diet and environment. Crit Rev Food Sci Nutr 2007; 47(1): 27-50.
    • (2007) Crit Rev Food Sci Nutr , vol.47 , Issue.1 , pp. 27-50
    • Hwang, E.S.1    Bowen, P.E.2
  • 209
    • 84942418028 scopus 로고    scopus 로고
    • The role of fatty acids in insulin resistance
    • Sears B, Perry M. The role of fatty acids in insulin resistance. Lipids Health Dis 2015; 14(1): 121. doi: 10.1186/s12944-015-0123-1
    • (2015) Lipids Health Dis , vol.14 , Issue.1 , pp. 121
    • Sears, B.1    Perry, M.2
  • 210
    • 84880310742 scopus 로고    scopus 로고
    • Adipocytokine levels in obese and non-obese subjects: an observational study
    • Derosa G, Fogari E, D'Angelo A, et al. Adipocytokine levels in obese and non-obese subjects: an observational study. Inflammation 2013; 36(4): 914-920.
    • (2013) Inflammation , vol.36 , Issue.4 , pp. 914-920
    • Derosa, G.1    Fogari, E.2    D'Angelo, A.3
  • 211
    • 84877349617 scopus 로고    scopus 로고
    • Common mechanisms of dysfunctional adipose tissue and obesity-related cancers
    • Matafome P, Santos-Silva D, Sena CM, Seiça R. Common mechanisms of dysfunctional adipose tissue and obesity-related cancers. Diabetes Metab Res Rev 2013; 29(4): 285-295.
    • (2013) Diabetes Metab Res Rev , vol.29 , Issue.4 , pp. 285-295
    • Matafome, P.1    Santos-Silva, D.2    Sena, C.M.3    Seiça, R.4
  • 212
    • 34250710450 scopus 로고    scopus 로고
    • Adipose tissue function and plasticity orchestrate nutritional adaptation
    • Sethi JK, Vidal-Piug AJ. Adipose tissue function and plasticity orchestrate nutritional adaptation. J Lipid Res 2007; 48: 1253-1262.
    • (2007) J Lipid Res , vol.48 , pp. 1253-1262
    • Sethi, J.K.1    Vidal-Piug, A.J.2
  • 213
    • 0031821520 scopus 로고    scopus 로고
    • Understanding adipocyte differentiation
    • Gregoire FM, Smas CM, Sul HS. Understanding adipocyte differentiation. Physiol Rev 1998; 78: 783-809.
    • (1998) Physiol Rev , vol.78 , pp. 783-809
    • Gregoire, F.M.1    Smas, C.M.2    Sul, H.S.3
  • 214
    • 0346220288 scopus 로고    scopus 로고
    • Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes
    • Ruan H, Zarnowski MJ, Cushman SW, Lodish HF. Standard isolation of primary adipose cells from mouse epididymal fat pads induces inflammatory mediators and down-regulates adipocyte genes. J Biol Chem 2003; 278 (48): 47585-47593.
    • (2003) J Biol Chem , vol.278 , Issue.48 , pp. 47585-47593
    • Ruan, H.1    Zarnowski, M.J.2    Cushman, S.W.3    Lodish, H.F.4
  • 215
    • 84904670754 scopus 로고    scopus 로고
    • Putative role of adipose tissue in growth and metabolism of colon cancer cells
    • Schwartz B, Yehuda-Shnaidman E. Putative role of adipose tissue in growth and metabolism of colon cancer cells. Front Oncol 2014; 4: 164.
    • (2014) Front Oncol , vol.4 , pp. 164
    • Schwartz, B.1    Yehuda-Shnaidman, E.2
  • 216
    • 81255157465 scopus 로고    scopus 로고
    • Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth
    • Nieman KM, Kenny HA, Penicka CV, et al. Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Nat Med 2011; 17(11): 1498-1503.
    • (2011) Nat Med , vol.17 , Issue.11 , pp. 1498-1503
    • Nieman, K.M.1    Kenny, H.A.2    Penicka, C.V.3
  • 217
    • 84943339748 scopus 로고    scopus 로고
    • Stromal Cells Derived from Visceral and Obese Adipose Tissue Promote Growth of Ovarian Cancers
    • Zhang Y, Nowicka A, Solley TN, et al. Stromal Cells Derived from Visceral and Obese Adipose Tissue Promote Growth of Ovarian Cancers. PLoS One 2015; 10(8): e0136361.
    • (2015) PLoS One , vol.10 , Issue.8
    • Zhang, Y.1    Nowicka, A.2    Solley, T.N.3
  • 218
    • 84949088183 scopus 로고    scopus 로고
    • Expression of cancer-associated fibroblast-related proteins in adipose stroma of breast cancer
    • Jung YY, Lee YK, Koo JS. Expression of cancer-associated fibroblast-related proteins in adipose stroma of breast cancer. Tumour Biol 2015; 36(11): 8685-95.
    • (2015) Tumour Biol , vol.36 , Issue.11 , pp. 8685-8695
    • Jung, Y.Y.1    Lee, Y.K.2    Koo, J.S.3
  • 219
    • 84928649587 scopus 로고    scopus 로고
    • Adipose tissue, obesity and adipokines: role in cancer promotion
    • Booth A, Magnuson A, Fouts J, Foster M. Adipose tissue, obesity and adipokines: role in cancer promotion. Horm Mol Biol Clin Investig 2015; 21(1): 57-74.
    • (2015) Horm Mol Biol Clin Investig , vol.21 , Issue.1 , pp. 57-74
    • Booth, A.1    Magnuson, A.2    Fouts, J.3    Foster, M.4
  • 220
    • 74549167737 scopus 로고    scopus 로고
    • Dietary and genetic obesity promote liver inflammation and tumor genesis by enhancing IL-6 and TNF expression
    • Park EJ, Lee JH, Yu GY, et al. Dietary and genetic obesity promote liver inflammation and tumor genesis by enhancing IL-6 and TNF expression. Cell 2010; 140(2): 197-208.
    • (2010) Cell , vol.140 , Issue.2 , pp. 197-208
    • Park, E.J.1    Lee, J.H.2    Yu, G.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.