Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype

Circulation Research

Volumn 111, Issue 9, 2012, Pages 1176-1189

  Sansbury, Brian E ^a,b   Cummins, Timothy D ^a,b   Tang, Yunan ^b   Hellmann, Jason ^a,b   Holden, Candice R ^a,b   Harbeson, Matthew A ^b   Chen, Yang ^d   Patel, Rakesh P ^e   Spite, Matthew ^a,b   Bhatnagar, Aruni ^a,b,c   Hil, Bradford G ^a,b,c  

^a University of Louisville School of Medicine   (United States)

^b Diabetes and Obesity Center   (United States)

^c UNIVERSITY OF LOUISVILLE   (United States)

^d METABOLON INC   (United States)

^e UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

adipose tissue; cardiovascular disease; diabetes; endothelial nitric oxide synthase; metabolism; mitochondria; obesity

Indexed keywords

CHOLESTEROL; ENDOTHELIAL NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TRIACYLGLYCEROL;

ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; FATTY ACID OXIDATION; GENE EXPRESSION; GLUCOSE INTOLERANCE; HYPERINSULINEMIA; INSULIN RESISTANCE; MALE; METABOLIC RATE; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOCYTES; AMINO ACIDS; ANIMALS; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; HYPERTROPHY; INSULIN RESISTANCE; LIPID METABOLISM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRIC OXIDE SYNTHASE TYPE III; OBESITY; PHENOTYPE; PPAR ALPHA; PPAR GAMMA;

EID: 84867743194     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.112.266395     Document Type: Article

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