Hypoxia-inducible factor 1 α regulates a SOCS3-STAT3-adiponectin signal transduction pathway in adipocytes

Journal of Biological Chemistry

Volumn 288, Issue 6, 2013, Pages 3844-3857

  Jiang, Changtao ^a   Kim, Jung Hwan ^a   Li, Fei ^a   Qu, Aijuan ^a   Gavrilova, Oksana ^b   Shah, Yatrik M ^a,c   Gonzalez, Frank J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3T3-L1 ADIPOCYTES; ADIPOCYTES; ADIPONECTIN; ADIPOSE TISSUE; CHROMATIN IMMUNOPRECIPITATION; DIET-INDUCED OBESITY; ENERGY METABOLISM; GENETIC ABLATION; HYPOXIA-INDUCIBLE FACTOR 1; IN-VITRO; IN-VIVO; INSULIN RESISTANCE; LUCIFERASE ASSAYS; MECHANISTIC STUDIES; POTENTIAL UTILITY; RISK FACTORS; SERUM ADIPONECTIN; SIGNAL TRANSDUCTION PATHWAYS; TARGET GENES; TARGET TISSUES; TYPE-2 DIABETES;

GENES; INSULIN; SIGNAL TRANSDUCTION; TISSUE;

NUTRITION;

ACRIFLAVINE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LUCIFERASE; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN 3T3; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ASSAY; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; INSULIN RESISTANCE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SOCS3 GENE;

3T3-L1 CELLS; ACRIFLAVINE; ADIPOCYTES; ADIPONECTIN; ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; DIABETES MELLITUS, TYPE 2; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN RESISTANCE; MICE; MICE, KNOCKOUT; OBESITY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 84873684881     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.426338     Document Type: Article

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