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Volumn 63, Issue 12, 2014, Pages 3982-3991

Immune cell crosstalk in obesity: A key role for costimulation?

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD137 ANTIGEN; CD137 LIGAND; CD40 ANTIGEN; CD40 LIGAND; CD86 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; T LYMPHOCYTE ANTIGEN; ADIPOCYTOKINE; CYTOKINE; T LYMPHOCYTE RECEPTOR;

EID: 84911891418     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0272     Document Type: Article
Times cited : (90)

References (77)
  • 1
    • 84857985148 scopus 로고    scopus 로고
    • The cellular and signaling networks linking the immune system and metabolism in disease
    • Osborn O, Olefsky JM. The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med 2012;18:363-374
    • (2012) Nat Med , vol.18 , pp. 363-374
    • Osborn, O.1    Olefsky, J.M.2
  • 2
    • 0001660570 scopus 로고
    • Zur therapie des diabetes mellitus, insbesondere über die anwendung des salicylsauren natron bei demsellben
    • in German
    • Ebstein W. Zur therapie des diabetes mellitus, insbesondere über die anwendung des salicylsauren natron bei demsellben. Berliner Klinische Wochenschrift 1876;13:337-340 [in German]
    • (1876) Berliner Klinische Wochenschrift , vol.13 , pp. 337-340
    • Ebstein, W.1
  • 3
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993;259:87-91
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 5
    • 84878785347 scopus 로고    scopus 로고
    • Immunological goings-on in visceral adipose tissue
    • Mathis D. Immunological goings-on in visceral adipose tissue. Cell Metab 2013;17:851-859
    • (2013) Cell Metab , vol.17 , pp. 851-859
    • Mathis, D.1
  • 8
    • 33846026712 scopus 로고    scopus 로고
    • Obesity induces a phenotypic switch in adipose tissue macrophage polarization
    • Lumeng CN, Bodzin JL, Saltiel AR. Obesity induces a phenotypic switch in adipose tissue macrophage polarization. J Clin Invest 2007;117:175-184
    • (2007) J Clin Invest , vol.117 , pp. 175-184
    • Lumeng, C.N.1    Bodzin, J.L.2    Saltiel, A.R.3
  • 9
    • 52749092267 scopus 로고    scopus 로고
    • Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
    • Patsouris D, Li P-P, Thapar D, Chapman J, Olefsky JM, Neels JG. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab 2008;8:301-309
    • (2008) Cell Metab , vol.8 , pp. 301-309
    • Patsouris, D.1    Li, P.-P.2    Thapar, D.3    Chapman, J.4    Olefsky, J.M.5    Neels, J.G.6
  • 10
    • 84885436588 scopus 로고    scopus 로고
    • The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance
    • Phieler J, Chung K-J, Chatzigeorgiou A, et al. The complement anaphylatoxin C5a receptor contributes to obese adipose tissue inflammation and insulin resistance. J Immunol 2013;191:4367-4374
    • (2013) J Immunol , vol.191 , pp. 4367-4374
    • Phieler, J.1    Chung, K.-J.2    Chatzigeorgiou, A.3
  • 11
    • 84868671526 scopus 로고    scopus 로고
    • Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase
    • Talukdar S, Oh Y, Bandyopadhyay G, et al. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med 2012;18:1407-1412
    • (2012) Nat Med , vol.18 , pp. 1407-1412
    • Talukdar, S.1    Oh, Y.2    Bandyopadhyay, G.3
  • 12
    • 79953815551 scopus 로고    scopus 로고
    • Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis
    • Wu D, Molofsky AB, Liang H-E, et al. Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis. Science 2011;332:243-247
    • (2011) Science , vol.332 , pp. 243-247
    • Wu, D.1    Molofsky, A.B.2    Liang, H.-E.3
  • 13
    • 68349160704 scopus 로고    scopus 로고
    • Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice
    • Liu J, Divoux A, Sun J, et al. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat Med 2009;15:940-945
    • (2009) Nat Med , vol.15 , pp. 940-945
    • Liu, J.1    Divoux, A.2    Sun, J.3
  • 14
    • 68349137821 scopus 로고    scopus 로고
    • Normalization of obesity-associated insulin resistance through immunotherapy
    • Winer S, Chan Y, Paltser G, et al. Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 2009;15:921-929
    • (2009) Nat Med , vol.15 , pp. 921-929
    • Winer, S.1    Chan, Y.2    Paltser, G.3
  • 15
    • 68349148211 scopus 로고    scopus 로고
    • Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
    • Feuerer M, Herrero L, Cipolletta D, et al. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 2009;15:930-939
    • (2009) Nat Med , vol.15 , pp. 930-939
    • Feuerer, M.1    Herrero, L.2    Cipolletta, D.3
  • 17
    • 84881452345 scopus 로고    scopus 로고
    • Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance
    • Priceman SJ, Kujawski M, Shen S, et al. Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance. Proc Natl Acad Sci U S A 2013;110:13079-13084
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 13079-13084
    • Priceman, S.J.1    Kujawski, M.2    Shen, S.3
  • 18
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S, Manabe I, Nagasaki M, et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009;15:914-920
    • (2009) Nat Med , vol.15 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3
  • 19
    • 84862986986 scopus 로고    scopus 로고
    • PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
    • Cipolletta D, Feuerer M, Li A, et al. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature 2012;486:549-553
    • (2012) Nature , vol.486 , pp. 549-553
    • Cipolletta, D.1    Feuerer, M.2    Li, A.3
  • 20
    • 84880617814 scopus 로고    scopus 로고
    • Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals
    • Fabbrini E, Cella M, McCartney SA, et al. Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals. Gastroenterology 2013;145:366-374
    • (2013) Gastroenterology , vol.145 , pp. 366-374
    • Fabbrini, E.1    Cella, M.2    McCartney, S.A.3
  • 21
    • 80053324882 scopus 로고    scopus 로고
    • Impact of CD1d deficiency on metabolism
    • Kotas ME, Lee H-Y, Gillum MP, et al. Impact of CD1d deficiency on metabolism. PLoS One 2011;6:e25478
    • (2011) PLoS One , vol.6 , pp. e25478
    • Kotas, M.E.1    Lee, H.-Y.2    Gillum, M.P.3
  • 22
    • 84859997837 scopus 로고    scopus 로고
    • Activation of natural killer T cells promotes M2 macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity
    • Ji Y, Sun S, Xu A, et al. Activation of natural killer T cells promotes M2 macrophage polarization in adipose tissue and improves systemic glucose tolerance via interleukin-4 (IL-4)/STAT6 protein signaling axis in obesity. J Biol Chem 2012;287:13561-13571
    • (2012) J Biol Chem , vol.287 , pp. 13561-13571
    • Ji, Y.1    Sun, S.2    Xu, A.3
  • 23
    • 84865992180 scopus 로고    scopus 로고
    • Natural killer T cells in adipose tissue prevent insulin resistance
    • Schipper HS, Rakhshandehroo M, van de Graaf SFJ, et al. Natural killer T cells in adipose tissue prevent insulin resistance. J Clin Invest 2012;122:3343-3354
    • (2012) J Clin Invest , vol.122 , pp. 3343-3354
    • Schipper, H.S.1    Rakhshandehroo, M.2    Van De Graaf, S.F.J.3
  • 24
    • 84879120134 scopus 로고    scopus 로고
    • Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice
    • Strodthoff D, Lundberg AM, Agardh HE, et al. Lack of invariant natural killer T cells affects lipid metabolism in adipose tissue of diet-induced obese mice. Arterioscler Thromb Vasc Biol 2013;33:1189-1196
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1189-1196
    • Strodthoff, D.1    Lundberg, A.M.2    Agardh, H.E.3
  • 25
    • 84907974271 scopus 로고    scopus 로고
    • Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding
    • Martin-Murphy BV, You Q, Wang H, et al. Mice lacking natural killer T cells are more susceptible to metabolic alterations following high fat diet feeding. PLoS One 2014;9:e80949
    • (2014) PLoS One , vol.9 , pp. e80949
    • Martin-Murphy, B.V.1    You, Q.2    Wang, H.3
  • 26
    • 79958022995 scopus 로고    scopus 로고
    • Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity
    • Mantell BS, Stefanovic-Racic M, Yang X, Dedousis N, Sipula IJ, O'Doherty RM. Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity. PLoS One 2011;6:e19831
    • (2011) PLoS One , vol.6 , pp. e19831
    • Mantell, B.S.1    Stefanovic-Racic, M.2    Yang, X.3    Dedousis, N.4    Sipula, I.J.5    O'Doherty, R.M.6
  • 27
    • 75149169811 scopus 로고    scopus 로고
    • Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice
    • Ohmura K, Ishimori N, Ohmura Y, et al. Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice. Arterioscler Thromb Vasc Biol 2010;30:193-199
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 193-199
    • Ohmura, K.1    Ishimori, N.2    Ohmura, Y.3
  • 28
    • 84857470273 scopus 로고    scopus 로고
    • Type II NKT cells stimulate dietinduced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance
    • Satoh M, Andoh Y, Clingan CS, et al. Type II NKT cells stimulate dietinduced obesity by mediating adipose tissue inflammation, steatohepatitis and insulin resistance. PLoS One 2012;7:e30568
    • (2012) PLoS One , vol.7 , pp. e30568
    • Satoh, M.1    Andoh, Y.2    Clingan, C.S.3
  • 29
    • 84860794660 scopus 로고    scopus 로고
    • Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice
    • Wu L, Parekh VV, Gabriel CL, et al. Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. Proc Natl Acad Sci U S A 2012;109:E1143-E1152
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. E1143-E1152
    • Wu, L.1    Parekh, V.V.2    Gabriel, C.L.3
  • 30
    • 85027938385 scopus 로고    scopus 로고
    • B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
    • Winer DA, Winer S, Shen L, et al. B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies. Nat Med 2011;17:610-617
    • (2011) Nat Med , vol.17 , pp. 610-617
    • Winer, D.A.1    Winer, S.2    Shen, L.3
  • 31
    • 46249117032 scopus 로고    scopus 로고
    • T-lymphocyte infiltration in visceral adipose tissue: A primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance
    • Kintscher U, Hartge M, Hess K, et al. T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Arterioscler Thromb Vasc Biol 2008;28:1304-1310
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1304-1310
    • Kintscher, U.1    Hartge, M.2    Hess, K.3
  • 32
    • 84875463042 scopus 로고    scopus 로고
    • Molecular mechanisms of T cell co-stimulation and coinhibition
    • Chen L, Flies DB. Molecular mechanisms of T cell co-stimulation and coinhibition. Nat Rev Immunol 2013;13:227-242
    • (2013) Nat Rev Immunol , vol.13 , pp. 227-242
    • Chen, L.1    Flies, D.B.2
  • 33
    • 84865461206 scopus 로고    scopus 로고
    • Identi fication of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 responses in mice and patients
    • Bertola A, Ciucci T, Rousseau D, et al. Identi fication of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 responses in mice and patients. Diabetes 2012;61:2238-2247
    • (2012) Diabetes , vol.61 , pp. 2238-2247
    • Bertola, A.1    Ciucci, T.2    Rousseau, D.3
  • 34
    • 84878800136 scopus 로고    scopus 로고
    • Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice
    • Morris DL, Cho KW, Delproposto JL, et al. Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice. Diabetes 2013;62:2762-2772
    • (2013) Diabetes , vol.62 , pp. 2762-2772
    • Morris, D.L.1    Cho, K.W.2    Delproposto, J.L.3
  • 35
    • 84875280888 scopus 로고    scopus 로고
    • Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation
    • Deng T, Lyon CJ, Minze LJ, et al. Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation. Cell Metab 2013;17:411-422
    • (2013) Cell Metab , vol.17 , pp. 411-422
    • Deng, T.1    Lyon, C.J.2    Minze, L.J.3
  • 36
    • 84896726991 scopus 로고    scopus 로고
    • B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance
    • Winer DA, Winer S, Chng MHY, Shen L, Engleman EG. B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance. Cell Mol Life Sci 2014;71:1033-1043
    • (2014) Cell Mol Life Sci , vol.71 , pp. 1033-1043
    • Winer, D.A.1    Winer, S.2    Chng, M.H.Y.3    Shen, L.4    Engleman, E.G.5
  • 37
    • 80155193132 scopus 로고    scopus 로고
    • Co-stimulatory molecules in and beyond co-stimulation - tipping the balance in atherosclerosis?
    • Gerdes N, Zirlik A. Co-stimulatory molecules in and beyond co-stimulation - tipping the balance in atherosclerosis? Thromb Haemost 2011;106:804-813
    • (2011) Thromb Haemost , vol.106 , pp. 804-813
    • Gerdes, N.1    Zirlik, A.2
  • 38
    • 84874051661 scopus 로고    scopus 로고
    • CD40-CD40L: Linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications
    • Seijkens T, Kusters P, Engel D, Lutgens E. CD40-CD40L: linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications. Diab Vasc Dis Res 2013;10:115-122
    • (2013) Diab Vasc Dis Res , vol.10 , pp. 115-122
    • Seijkens, T.1    Kusters, P.2    Engel, D.3    Lutgens, E.4
  • 39
    • 70349157633 scopus 로고    scopus 로고
    • The immunobiology of CD154-CD40- TRAF interactions in atherosclerosis
    • Engel D, Seijkens T, Poggi M, et al. The immunobiology of CD154-CD40- TRAF interactions in atherosclerosis. Semin Immunol 2009;21:308-312
    • (2009) Semin Immunol , vol.21 , pp. 308-312
    • Engel, D.1    Seijkens, T.2    Poggi, M.3
  • 40
    • 65349119978 scopus 로고    scopus 로고
    • CD28 and CTLA-4 coreceptor expression and signal transduction
    • Rudd CE, Taylor A, Schneider H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol Rev 2009;229:12-26
    • (2009) Immunol Rev , vol.229 , pp. 12-26
    • Rudd, C.E.1    Taylor, A.2    Schneider, H.3
  • 41
    • 0035804254 scopus 로고    scopus 로고
    • ICOS co-stimulatory receptor is essential for T-cell activation and function
    • Dong C, Juedes AE, Temann UA, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 2001;409:97-101
    • (2001) Nature , vol.409 , pp. 97-101
    • Dong, C.1    Juedes, A.E.2    Temann, U.A.3
  • 42
    • 33748627960 scopus 로고    scopus 로고
    • Regulation of T:B cell interactions by the inducible costimulator molecule: Does ICOS "induce" disease?
    • Shilling RA, Bandukwala HS, Sperling AI. Regulation of T:B cell interactions by the inducible costimulator molecule: does ICOS "induce" disease? Clin Immunol 2006;121:13-18
    • (2006) Clin Immunol , vol.121 , pp. 13-18
    • Shilling, R.A.1    Bandukwala, H.S.2    Sperling, A.I.3
  • 43
    • 25444507136 scopus 로고    scopus 로고
    • PD-1/PD-L pathway and autoimmunity
    • Okazaki T, Wang J. PD-1/PD-L pathway and autoimmunity. Autoimmunity 2005;38:353-357
    • (2005) Autoimmunity , vol.38 , pp. 353-357
    • Okazaki, T.1    Wang, J.2
  • 44
    • 0030005099 scopus 로고    scopus 로고
    • Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes
    • Agata Y, Kawasaki A, Nishimura H, et al. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes. Int Immunol 1996;8:765-772
    • (1996) Int Immunol , vol.8 , pp. 765-772
    • Agata, Y.1    Kawasaki, A.2    Nishimura, H.3
  • 45
    • 80052971178 scopus 로고    scopus 로고
    • CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice
    • Poggi M, Engel D, Christ A, et al. CD40L deficiency ameliorates adipose tissue inflammation and metabolic manifestations of obesity in mice. Arterioscler Thromb Vasc Biol 2011;31:2251-2260
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2251-2260
    • Poggi, M.1    Engel, D.2    Christ, A.3
  • 46
    • 84894377101 scopus 로고    scopus 로고
    • Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance
    • [published correction appears in Proc Natl Acad Sci U S A 2014;111:4644].
    • Chatzigeorgiou A, Seijkens T, Zarzycka B, et al. Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance [published correction appears in Proc Natl Acad Sci U S A 2014;111:4644]. Proc Natl Acad Sci U S A 2014;111:2686-2691
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 2686-2691
    • Chatzigeorgiou, A.1    Seijkens, T.2    Zarzycka, B.3
  • 47
    • 77955965216 scopus 로고    scopus 로고
    • OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology
    • Ishii N, Takahashi T, Soroosh P, Sugamura K. OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology. Adv Immunol 2010;105:63-98
    • (2010) Adv Immunol , vol.105 , pp. 63-98
    • Ishii, N.1    Takahashi, T.2    Soroosh, P.3    Sugamura, K.4
  • 48
    • 84872157416 scopus 로고    scopus 로고
    • 4-1BB/4-1BBL interaction promotes obesity-induced adipose inflammation by triggering bidirectional inflammatory signaling in adipocytes/macrophages
    • Tu TH, Kim CS, Goto T, Kawada T, Kim B-S, Yu R. 4-1BB/4-1BBL interaction promotes obesity-induced adipose inflammation by triggering bidirectional inflammatory signaling in adipocytes/macrophages. Mediators Inflamm 2012;2012:972629
    • (2012) Mediators Inflamm , vol.2012 , pp. 972629
    • Tu, T.H.1    Kim, C.S.2    Goto, T.3    Kawada, T.4    Kim, B.-S.5    Yu, R.6
  • 49
    • 82255164680 scopus 로고    scopus 로고
    • Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders
    • Kim C-S, Kim JG, Lee B-J, et al. Deficiency for costimulatory receptor 4-1BB protects against obesity-induced inflammation and metabolic disorders. Diabetes 2011;60:3159-3168
    • (2011) Diabetes , vol.60 , pp. 3159-3168
    • Kim, C.-S.1    Kim, J.G.2    Lee, B.-J.3
  • 50
    • 79951822440 scopus 로고    scopus 로고
    • Role of CD27/CD70 pathway of activation in immunity and tolerance
    • Denoeud J, Moser M. Role of CD27/CD70 pathway of activation in immunity and tolerance. J Leukoc Biol 2011;89:195-203
    • (2011) J Leukoc Biol , vol.89 , pp. 195-203
    • Denoeud, J.1    Moser, M.2
  • 51
    • 79960345581 scopus 로고    scopus 로고
    • HVEM-deficient mice fed a high-fat diet are protected from adipose tissue inflammation and glucose intolerance
    • Kim H-J, Kim H-M, Kim C-S, et al. HVEM-deficient mice fed a high-fat diet are protected from adipose tissue inflammation and glucose intolerance. FEBS Lett 2011;585:2285-2290
    • (2011) FEBS Lett , vol.585 , pp. 2285-2290
    • Kim, H.-J.1    Kim, H.-M.2    Kim, C.-S.3
  • 52
    • 84927761703 scopus 로고    scopus 로고
    • Dual role of B7 costimulation in obesity-related non-alcoholic steatohepatitis and metabolic dysregulation
    • Chatzigeorgiou A, Chung KJ, Garcia-Martin R, et al. Dual role of B7 costimulation in obesity-related non-alcoholic steatohepatitis and metabolic dysregulation. Hepatology 2014;60:1196-1210
    • (2014) Hepatology , vol.60 , pp. 1196-1210
    • Chatzigeorgiou, A.1    Chung, K.J.2    Garcia-Martin, R.3
  • 53
    • 84897849549 scopus 로고    scopus 로고
    • T-cell costimulation protects obesityinduced adipose inflammation and insulin resistance
    • Zhong J, Rao X, Braunstein Z, et al. T-cell costimulation protects obesityinduced adipose inflammation and insulin resistance. Diabetes 2014;63:1289-1302
    • (2014) Diabetes , vol.63 , pp. 1289-1302
    • Zhong, J.1    Rao, X.2    Braunstein, Z.3
  • 54
    • 57549108516 scopus 로고    scopus 로고
    • B7-1 and B7-2 differentially control peripheral homeostasis of CD4(+)CD25(+)Foxp3(+) regulatory T cells
    • Zeng M, Guinet E, Nouri-Shirazi M. B7-1 and B7-2 differentially control peripheral homeostasis of CD4(+)CD25(+)Foxp3(+) regulatory T cells. Transpl Immunol 2009;20:171-179
    • (2009) Transpl Immunol , vol.20 , pp. 171-179
    • Zeng, M.1    Guinet, E.2    Nouri-Shirazi, M.3
  • 55
    • 84881543795 scopus 로고    scopus 로고
    • CTLA-4Ig immunotherapy of obesityinduced insulin resistance by manipulation of macrophage polarization in adipose tissues
    • Fujii M, Inoguchi T, Batchuluun B, et al. CTLA-4Ig immunotherapy of obesityinduced insulin resistance by manipulation of macrophage polarization in adipose tissues. Biochem Biophys Res Commun 2013;438:103-109
    • (2013) Biochem Biophys Res Commun , vol.438 , pp. 103-109
    • Fujii, M.1    Inoguchi, T.2    Batchuluun, B.3
  • 56
    • 84888302854 scopus 로고    scopus 로고
    • Lymphocytic tumor necrosis factor receptor superfamily co-stimulatory molecules in the pathogenesis of atherosclerosis
    • Smeets E, Meiler S, Lutgens E. Lymphocytic tumor necrosis factor receptor superfamily co-stimulatory molecules in the pathogenesis of atherosclerosis. Curr Opin Lipidol 2013;24:518-524
    • (2013) Curr Opin Lipidol , vol.24 , pp. 518-524
    • Smeets, E.1    Meiler, S.2    Lutgens, E.3
  • 57
    • 67349103904 scopus 로고    scopus 로고
    • The inflammatory receptor CD40 is expressed on human adipocytes: Contribution to crosstalk between lymphocytes and adipocytes
    • Poggi M, Jager J, Paulmyer-Lacroix O, et al. The inflammatory receptor CD40 is expressed on human adipocytes: contribution to crosstalk between lymphocytes and adipocytes. Diabetologia 2009;52:1152-1163
    • (2009) Diabetologia , vol.52 , pp. 1152-1163
    • Poggi, M.1    Jager, J.2    Paulmyer-Lacroix, O.3
  • 58
    • 84874226366 scopus 로고    scopus 로고
    • Soluble CD40 ligand in morbidly obese patients: Effect of body mass index on recovery to normal levels after gastric bypass surgery
    • Baena-Fustegueras JA, Pardina E, Balada E, et al. Soluble CD40 ligand in morbidly obese patients: effect of body mass index on recovery to normal levels after gastric bypass surgery. JAMA Surg 2013;148:151-156
    • (2013) JAMA Surg , vol.148 , pp. 151-156
    • Baena-Fustegueras, J.A.1    Pardina, E.2    Balada, E.3
  • 60
    • 77952013973 scopus 로고    scopus 로고
    • CD40L induces inflammation and adipogenesis in adipose cells - A potential link between metabolic and cardiovascular disease
    • Missiou A, Wolf D, Platzer I, et al. CD40L induces inflammation and adipogenesis in adipose cells - a potential link between metabolic and cardiovascular disease. Thromb Haemost 2010;103:788-796
    • (2010) Thromb Haemost , vol.103 , pp. 788-796
    • Missiou, A.1    Wolf, D.2    Platzer, I.3
  • 61
    • 84857804227 scopus 로고    scopus 로고
    • CD40L deficiency attenuates dietinduced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies [published correction appears in PLoS One 2012;7: Doi:10.1371/annotation/84102aae-770a-41ae-9c15-4736ed129c17]
    • Wolf D, Jehle F, Ortiz Rodriguez A, et al. CD40L deficiency attenuates dietinduced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies [published correction appears in PLoS One 2012;7: doi:10.1371/annotation/84102aae-770a-41ae-9c15-4736ed129c17]. PLoS One 2012;7:e33026
    • (2012) PLoS One , vol.7 , pp. e33026
    • Wolf, D.1    Jehle, F.2    Ortiz Rodriguez, A.3
  • 62
    • 84902241067 scopus 로고    scopus 로고
    • Coinhibitory suppression of T cell activation by CD40 protects from obesity and adipose tissue inflammation in mice
    • Wolf D, Jehle F, Michel NA, et al. Coinhibitory suppression of T cell activation by CD40 protects from obesity and adipose tissue inflammation in mice. Circulation 2014;129:2414-2425
    • (2014) Circulation , vol.129 , pp. 2414-2425
    • Wolf, D.1    Jehle, F.2    Michel, N.A.3
  • 63
    • 84878565127 scopus 로고    scopus 로고
    • CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance
    • Guo C-A, Kogan S, Amano SU, et al. CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance. Am J Physiol Endocrinol Metab 2013;304:E951-E963
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , pp. E951-E963
    • Guo, C.-A.1    Kogan, S.2    Amano, S.U.3
  • 64
    • 79952585405 scopus 로고    scopus 로고
    • Ligation of CD46 to CD40 inhibits CD40 signaling in B cells
    • Jabara HH, Angelini F, Brodeur SR, Geha RS. Ligation of CD46 to CD40 inhibits CD40 signaling in B cells. Int Immunol 2011;23:215-221
    • (2011) Int Immunol , vol.23 , pp. 215-221
    • Jabara, H.H.1    Angelini, F.2    Brodeur, S.R.3    Geha, R.S.4
  • 65
    • 0032374052 scopus 로고    scopus 로고
    • Role of 4-1BB in immune responses
    • Vinay DS, Kwon BS. Role of 4-1BB in immune responses. Semin Immunol 1998;10:481-489
    • (1998) Semin Immunol , vol.10 , pp. 481-489
    • Vinay, D.S.1    Kwon, B.S.2
  • 66
    • 84905640163 scopus 로고    scopus 로고
    • Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters
    • Tu TH, Kim CS, Kang JH, et al. Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters. Int J Obes (Lond) 2014;38:1075-1082
    • (2014) Int J Obes (Lond) , vol.38 , pp. 1075-1082
    • Tu, T.H.1    Kim, C.S.2    Kang, J.H.3
  • 67
    • 77957272882 scopus 로고    scopus 로고
    • The immune signaling molecule 4-1BB stimulation reduces adiposity, insulin resistance, and hepatosteatosis in obese mice
    • Kim C-S, Tu TH, Kawada T, Kim B-S, Yu R. The immune signaling molecule 4-1BB stimulation reduces adiposity, insulin resistance, and hepatosteatosis in obese mice. Endocrinology 2010;151:4725-4735
    • (2010) Endocrinology , vol.151 , pp. 4725-4735
    • Kim, C.-S.1    Tu, T.H.2    Kawada, T.3    Kim, B.-S.4    Yu, R.5
  • 68
    • 74249099513 scopus 로고    scopus 로고
    • LIGHT is associated with hypertriglyceridemia in obese subjects and increased cytokine secretion from cultured human adipocytes
    • Bassols J, Moreno-Navarrete JM, Ortega F, Ricart W, Fernandez-Real JM. LIGHT is associated with hypertriglyceridemia in obese subjects and increased cytokine secretion from cultured human adipocytes. Int J Obes (Lond) 2010;34:146-156
    • (2010) Int J Obes (Lond) , vol.34 , pp. 146-156
    • Bassols, J.1    Moreno-Navarrete, J.M.2    Ortega, F.3    Ricart, W.4    Fernandez-Real, J.M.5
  • 69
    • 79551503527 scopus 로고    scopus 로고
    • LIGHT/TNFSF14 enhances adipose tissue inflammatory responses through its interaction with HVEM
    • Kim H-M, Jeong C-S, Choi H-S, Kawada T, Yu R. LIGHT/TNFSF14 enhances adipose tissue inflammatory responses through its interaction with HVEM. FEBS Lett 2011;585:579-584
    • (2011) FEBS Lett , vol.585 , pp. 579-584
    • Kim, H.-M.1    Jeong, C.-S.2    Choi, H.-S.3    Kawada, T.4    Yu, R.5
  • 70
    • 34247371874 scopus 로고    scopus 로고
    • Lymphotoxin beta receptor-dependent control of lipid homeostasis
    • Lo JC, Wang Y, Tumanov AV, et al. Lymphotoxin beta receptor-dependent control of lipid homeostasis. Science 2007;316:285-288
    • (2007) Science , vol.316 , pp. 285-288
    • Lo, J.C.1    Wang, Y.2    Tumanov, A.V.3
  • 71
  • 72
    • 0033965079 scopus 로고    scopus 로고
    • Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand
    • Kawai T, Andrews D, Colvin R, Sachs D, Cosimi A. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat Med 2000;6:114
    • (2000) Nat Med , vol.6 , pp. 114
    • Kawai, T.1    Andrews, D.2    Colvin, R.3    Sachs, D.4    Cosimi, A.5
  • 73
    • 22844449094 scopus 로고    scopus 로고
    • Safety and tolerability of antagonist antihuman CD40 Mab ch5D12 in patients with moderate to severe Crohn's disease
    • Kasran A, Boon L, Wortel CH, et al. Safety and tolerability of antagonist antihuman CD40 Mab ch5D12 in patients with moderate to severe Crohn's disease. Aliment Pharmacol Ther 2005;22:111-122
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 111-122
    • Kasran, A.1    Boon, L.2    Wortel, C.H.3
  • 75
    • 84901720853 scopus 로고    scopus 로고
    • Longterm safety, efficacy, and inhibition of structural damage progression over 5 years of treatment with abatacept in patients with rheumatoid arthritis in the abatacept in inadequate responders to methotrexate trial
    • Kremer JM, Peterfy C, Russell AS, et al. Longterm safety, efficacy, and inhibition of structural damage progression over 5 years of treatment with abatacept in patients with rheumatoid arthritis in the abatacept in inadequate responders to methotrexate trial. J Rheumatol 2014;41:1077-1087
    • (2014) J Rheumatol , vol.41 , pp. 1077-1087
    • Kremer, J.M.1    Peterfy, C.2    Russell, A.S.3
  • 76
    • 84899007255 scopus 로고    scopus 로고
    • Kidney transplant recipients treated with belatacept exhibit increased naïve and transitional B cells
    • Leibler C, Matignon M, Pilon C, et al. Kidney transplant recipients treated with belatacept exhibit increased naïve and transitional B cells. Am J Transplant 2014;14:1173-1182
    • (2014) Am J Transplant , vol.14 , pp. 1173-1182
    • Leibler, C.1    Matignon, M.2    Pilon, C.3
  • 77
    • 77958566322 scopus 로고    scopus 로고
    • Co-stimulation blockade as a new strategy in kidney transplantation: Benefits and limits
    • Snanoudj R, Zuber J, Legendre C. Co-stimulation blockade as a new strategy in kidney transplantation: benefits and limits. Drugs 2010;70:2121-2131
    • (2010) Drugs , vol.70 , pp. 2121-2131
    • Snanoudj, R.1    Zuber, J.2    Legendre, C.3


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