-
1
-
-
78649364332
-
Hypoxia-inducible factors and the response to hypoxic stress
-
10.1016/j.molcel.2010.09.022 20965423
-
Hypoxia-inducible factors and the response to hypoxic stress. Majmundar AJ, Wong WJ, Simon MC, Mol Cell 2010 40 294 309 10.1016/j.molcel.2010.09.022 20965423
-
(2010)
Mol Cell
, vol.40
, pp. 294-309
-
-
Majmundar, A.J.1
Wong, W.J.2
Simon, M.C.3
-
2
-
-
57149142495
-
The impact of O2 availability on human cancer
-
10.1038/nrc2540 18987634
-
The impact of O2 availability on human cancer. Bertout JA, Patel SA, Simon MC, Nat Rev Cancer 2008 8 967 975 10.1038/nrc2540 18987634
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 967-975
-
-
Bertout, J.A.1
Patel, S.A.2
Simon, M.C.3
-
3
-
-
84859445000
-
Hypoxia-inducible factors: Mediators of cancer progression and targets for cancer therapy
-
10.1016/j.tips.2012.01.005 22398146
-
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy. Semenza GL, Trends Pharmacol Sci 2012 33 207 214 10.1016/j.tips.2012.01.005 22398146
-
(2012)
Trends Pharmacol Sci
, vol.33
, pp. 207-214
-
-
Semenza, G.L.1
-
4
-
-
84865575592
-
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells
-
10.1016/j.molmed.2012.08.001 22921864
-
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells. Semenza GL, Trends Mol Med 2012 18 534 543 10.1016/j.molmed.2012.08.001 22921864
-
(2012)
Trends Mol Med
, vol.18
, pp. 534-543
-
-
Semenza, G.L.1
-
5
-
-
78650373860
-
Hypoxia and hypoxia-inducible factors: Master regulators of metastasis
-
Hypoxia and hypoxia-inducible factors: master regulators of metastasis. Lu X, Kang Y, Clin Cancer Res 2011 16 5928 5935
-
(2011)
Clin Cancer Res
, vol.16
, pp. 5928-5935
-
-
Lu, X.1
Kang, Y.2
-
6
-
-
0035910429
-
Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide
-
11056166
-
Identification of hypoxia-inducible factor 1 ancillary sequence and its function in vascular endothelial growth factor gene induction by hypoxia and nitric oxide. Kimura H, Weisz A, Ogura T, Hitomi Y, Kurashima Y, Hashimoto K, D'Acquisto F, Makuuchi M, Esumi H, J Biol Chem 2001 276 2292 2298 11056166
-
(2001)
J Biol Chem
, vol.276
, pp. 2292-2298
-
-
Kimura, H.1
Weisz, A.2
Ogura, T.3
Hitomi, Y.4
Kurashima, Y.5
Hashimoto, K.6
D'Acquisto, F.7
Makuuchi, M.8
Esumi, H.9
-
7
-
-
0037374289
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor-1
-
12615733
-
Regulation of colon carcinoma cell invasion by hypoxia-inducible factor-1. Krishnamachary B, Berg-Dixon S, Kelly B, Agani F, Feldser D, Ferreira G, Iyer N, LaRusch J, Pak B, Taghavi P, Semenza GL, Cancer Res 2003 63 1138 1143 12615733
-
(2003)
Cancer Res
, vol.63
, pp. 1138-1143
-
-
Krishnamachary, B.1
Berg-Dixon, S.2
Kelly, B.3
Agani, F.4
Feldser, D.5
Ferreira, G.6
Iyer, N.7
Larusch, J.8
Pak, B.9
Taghavi, P.10
Semenza, G.L.11
-
8
-
-
17144416530
-
Differential gene up-regulation by hypoxia-inducible factor-1α and hypoxia-inducible factor-2α in HEK293T cells
-
15833863
-
Differential gene up-regulation by hypoxia-inducible factor-1α and hypoxia-inducible factor-2α in HEK293T cells. Wang V, Davis DA, Haque M, Huang LE, Yarchoan R, Cancer Res 2005 65 3299 3306 15833863
-
(2005)
Cancer Res
, vol.65
, pp. 3299-3306
-
-
Wang, V.1
Davis, D.A.2
Haque, M.3
Huang, L.E.4
Yarchoan, R.5
-
9
-
-
72449133970
-
Adaptation of human CD4+ T cells pathophysiological hypoxia: A transcriptome analysis
-
10.3899/jrheum.090255 19884271
-
Adaptation of human CD4+ T cells pathophysiological hypoxia: a transcriptome analysis. Gaber T, Haupl T, Sandig G, Tykwinska K, Fangradt M, Tschirschmann M, Hahne M, Dziuria R, Erekul K, Lautenbach M, Kolar P, Burmester GR, Buttgereit F, J Rheumatol 2009 36 2655 2669 10.3899/jrheum.090255 19884271
-
(2009)
J Rheumatol
, vol.36
, pp. 2655-2669
-
-
Gaber, T.1
Haupl, T.2
Sandig, G.3
Tykwinska, K.4
Fangradt, M.5
Tschirschmann, M.6
Hahne, M.7
Dziuria, R.8
Erekul, K.9
Lautenbach, M.10
Kolar, P.11
Burmester, G.R.12
Buttgereit, F.13
-
10
-
-
69049111041
-
An integrative genomics approach identifies hypoxia-inducible factor-1 (HIF-1)-target genes that form the core response to hypoxia
-
10.1093/nar/gkp425 19491311
-
An integrative genomics approach identifies hypoxia-inducible factor-1 (HIF-1)-target genes that form the core response to hypoxia. Benita Y, Kikuchi H, Smith AD, Zhang MQ, Chung DC, Xavier RJ, Nucleic Acids Res 2009 37 4587 4602 10.1093/nar/gkp425 19491311
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 4587-4602
-
-
Benita, Y.1
Kikuchi, H.2
Smith, A.D.3
Zhang, M.Q.4
Chung, D.C.5
Xavier, R.J.6
-
11
-
-
84655161946
-
HIF1a and HIF2a: Sibling rivalry in hypoxic tumour growth and progression
-
HIF1a and HIF2a: sibling rivalry in hypoxic tumour growth and progression. Keith B, Johnson RS, Simon MC, Nat Rev Cancer 2012 12 9 22
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
12
-
-
33751252276
-
Cancer metastasis: Building a framework
-
10.1016/j.cell.2006.11.001 17110329
-
Cancer metastasis: building a framework. Gupta GP, Massague J, Cell 2006 127 679 695 10.1016/j.cell.2006.11.001 17110329
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
13
-
-
33645090169
-
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B
-
10.1158/0008-5472.CAN-05-3719 16510593
-
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B. Krishnamachary B, Zagzag D, Nagasawa H, Rainey K, Okuyama H, Baek JH, Semenza GL, Cancer Res 2006 66 2725 2731 10.1158/0008-5472.CAN-05-3719 16510593
-
(2006)
Cancer Res
, vol.66
, pp. 2725-2731
-
-
Krishnamachary, B.1
Zagzag, D.2
Nagasawa, H.3
Rainey, K.4
Okuyama, H.5
Baek, J.H.6
Semenza, G.L.7
-
14
-
-
33845724527
-
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and Snail
-
10.1128/MCB.00892-06 17060462
-
VHL promotes E2 box-dependent E-cadherin transcription by HIF-mediated regulation of SIP1 and Snail. Evans AJ, Russell RC, Roche O, Burry NT, Fish JE, Chow VW, Kim WY, Saravanan A, Maynard MA, Gervais ML, Sufan RI, Roberts AM, Wilson LA, Betten M, Vandewalle C, Berx G, Marsden PA, Irwin MS, The BT, Jewett MA, Ohh M, Mol Cell Biol 2007 27 157 169 10.1128/MCB.00892-06 17060462
-
(2007)
Mol Cell Biol
, vol.27
, pp. 157-169
-
-
Evans, A.J.1
Russell, R.C.2
Roche, O.3
Burry, N.T.4
Fish, J.E.5
Chow, V.W.6
Kim, W.Y.7
Saravanan, A.8
Maynard, M.A.9
Gervais, M.L.10
Sufan, R.I.11
Roberts, A.M.12
Wilson, L.A.13
Betten, M.14
Vandewalle, C.15
Berx, G.16
Marsden, P.A.17
Irwin, M.S.18
The, B.T.19
Jewett, M.A.20
Ohh, M.21
more..
-
15
-
-
40249113328
-
Direct regulation of TWIST by HIF-1α promotes metastasis
-
10.1038/ncb1691 18297062
-
Direct regulation of TWIST by HIF-1α promotes metastasis. Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Teng SC, Wu KJ, Nat Cell Biol 2008 10 295 305 10.1038/ncb1691 18297062
-
(2008)
Nat Cell Biol
, vol.10
, pp. 295-305
-
-
Yang, M.H.1
Wu, M.Z.2
Chiou, S.H.3
Chen, P.M.4
Chang, S.Y.5
Teng, S.C.6
Wu, K.J.7
-
16
-
-
34249289041
-
Snail, Zeb and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
10.1038/nrc2131 17508028
-
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Peinado H, Olmeda D, Cano A, Nat Rev Cancer 2007 7 415 428 10.1038/nrc2131 17508028
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
17
-
-
47749131186
-
TWIST activation by hypoxia inducible factor-1 (HIF-1): Implications in metastasis and development
-
10.4161/cc.7.14.6324 18635960
-
TWIST activation by hypoxia inducible factor-1 (HIF-1): implications in metastasis and development. Yang MH, Wu KJ, Cell Cycle 2008 7 2090 2096 10.4161/cc.7.14.6324 18635960
-
(2008)
Cell Cycle
, vol.7
, pp. 2090-2096
-
-
Yang, M.H.1
Wu, K.J.2
-
18
-
-
27144518237
-
A molecular role for lyxyl oxidase-like 2 enzyme in Snail regulation and tumor progression
-
10.1038/sj.emboj.7600781 16096638
-
A molecular role for lyxyl oxidase-like 2 enzyme in Snail regulation and tumor progression. Peinado H, la Cruz MC I-d, Olmeda D, Csiszar K, Fong KSK, Vega S, Nieto MA, Cano A, Portillo F, EMBO J 2005 24 3446 3458 10.1038/sj.emboj.7600781 16096638
-
(2005)
EMBO J
, vol.24
, pp. 3446-3458
-
-
Peinado, H.1
La Cruz Mc, I.-D.2
Olmeda, D.3
Csiszar, K.4
Fong, K.S.K.5
Vega, S.6
Nieto, M.A.7
Cano, A.8
Portillo, F.9
-
19
-
-
77950476293
-
ERβ impedes prostate cancer EMT by destabilizing HIF-1α and inhibiting VEGF-mediated snail nuclear localization: Implication for Gleason grading
-
10.1016/j.ccr.2010.02.030 20385358
-
ERβ impedes prostate cancer EMT by destabilizing HIF-1α and inhibiting VEGF-mediated snail nuclear localization: implication for Gleason grading. Mak P, Leav I, Pursell B, Bae D, Yang X, Taglienti CA, Gouvin LM, Sharma VM, Mercurio AM, Cancer Cell 2010 17 319 332 10.1016/j.ccr.2010.02.030 20385358
-
(2010)
Cancer Cell
, vol.17
, pp. 319-332
-
-
Mak, P.1
Leav, I.2
Pursell, B.3
Bae, D.4
Yang, X.5
Taglienti, C.A.6
Gouvin, L.M.7
Sharma, V.M.8
Mercurio, A.M.9
-
20
-
-
4544361863
-
Induction of ID2 expression by hypoxia-inducible factor-1: A role in dedifferentiation of hypoxic neuroblastoma cells
-
10.1074/jbc.M402904200 15252039
-
Induction of ID2 expression by hypoxia-inducible factor-1: a role in dedifferentiation of hypoxic neuroblastoma cells. Lofstedt T, Jogi A, Sigvardsson M, Gradin K, Poellinger L, Pahlman S, Axelson H, J Biol Chem 2004 279 39223 39231 10.1074/jbc.M402904200 15252039
-
(2004)
J Biol Chem
, vol.279
, pp. 39223-39231
-
-
Lofstedt, T.1
Jogi, A.2
Sigvardsson, M.3
Gradin, K.4
Poellinger, L.5
Pahlman, S.6
Axelson, H.7
-
21
-
-
77952801325
-
Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro
-
10.1158/0008-5472.CAN-09-4333 20442286
-
Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro. Aryee DN, Niedan S, Kauer M, Schwentner R, Bennani-Baiti IM, Ban J, Muehlbacher K, Kreppel M, Walker RL, Meltzer P, Poremba C, Kofler R, Kovar H, Cancer Res 2010 70 4015 4023 10.1158/0008-5472.CAN-09-4333 20442286
-
(2010)
Cancer Res
, vol.70
, pp. 4015-4023
-
-
Aryee, D.N.1
Niedan, S.2
Kauer, M.3
Schwentner, R.4
Bennani-Baiti, I.M.5
Ban, J.6
Muehlbacher, K.7
Kreppel, M.8
Walker, R.L.9
Meltzer, P.10
Poremba, C.11
Kofler, R.12
Kovar, H.13
-
22
-
-
77952324704
-
Activation of β-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis
-
10.1158/1078-0432.CCR-09-2610 20460486
-
Activation of β-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis. Liu L, Zhu XD, Wang WQ, Shen Y, Qin Y, Ren ZG, Sun HC, Tang ZY, Clin Cancer Res 2010 16 2740 2750 10.1158/1078-0432.CCR-09-2610 20460486
-
(2010)
Clin Cancer Res
, vol.16
, pp. 2740-2750
-
-
Liu, L.1
Zhu, X.D.2
Wang, W.Q.3
Shen, Y.4
Qin, Y.5
Ren, Z.G.6
Sun, H.C.7
Tang, Z.Y.8
-
23
-
-
77952964767
-
Hypoxia-inducible factor-1α modulates the down-regulation of the homeodomain protein CDX2 in colorectal cancer
-
20514449
-
Hypoxia-inducible factor-1α modulates the down-regulation of the homeodomain protein CDX2 in colorectal cancer. Zheng J, Sun X, Wang W, Lu S, Oncol Rep 2010 24 97 104 20514449
-
(2010)
Oncol Rep
, vol.24
, pp. 97-104
-
-
Zheng, J.1
Sun, X.2
Wang, W.3
Lu, S.4
-
24
-
-
77955047829
-
Hypoxic conversion of SMAD7 function from an inhibitor into a promoter of cell invasion
-
10.1158/0008-5472.CAN-09-3777 20551054
-
Hypoxic conversion of SMAD7 function from an inhibitor into a promoter of cell invasion. Heikkinen PT, Nummela M, Jokilehto T, Grenman R, Kahari VM, Jaakkola PM, Cancer Res 2010 70 5984 5993 10.1158/0008-5472.CAN-09-3777 20551054
-
(2010)
Cancer Res
, vol.70
, pp. 5984-5993
-
-
Heikkinen, P.T.1
Nummela, M.2
Jokilehto, T.3
Grenman, R.4
Kahari, V.M.5
Jaakkola, P.M.6
-
25
-
-
84865536482
-
HIF-1α-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism
-
10.1093/carcin/bgs217 22745382
-
HIF-1α-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism. Fu L, Chen L, Yang J, Ye T, Chen Y, Fang J, Carcinogenesis 2012 33 1664 1673 10.1093/carcin/bgs217 22745382
-
(2012)
Carcinogenesis
, vol.33
, pp. 1664-1673
-
-
Fu, L.1
Chen, L.2
Yang, J.3
Ye, T.4
Chen, Y.5
Fang, J.6
-
26
-
-
84867747419
-
Histone demethylase JMJD2B-mediated cell proliferation regulated by hypoxia and radiation in gastric cancer cell
-
Histone demethylase JMJD2B-mediated cell proliferation regulated by hypoxia and radiation in gastric cancer cell. Kim JG, Yi JM, Park SJ, Kim JS, Son TG, Yang K, Yoo MA, Heo K, Biochim Biophys Acta 2010 1819 1200 1207
-
(2010)
Biochim Biophys Acta
, vol.1819
, pp. 1200-1207
-
-
Kim, J.G.1
Yi, J.M.2
Park, S.J.3
Kim, J.S.4
Son, T.G.5
Yang, K.6
Yoo, M.A.7
Heo, K.8
-
27
-
-
84870608916
-
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
-
10.1073/pnas.1217394109 23129632
-
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression. Luo W, Chang R, Zhong J, Pandey A, Semenza GL, Proc Natl Acad Sci USA 2012 109 3367 E3376 10.1073/pnas.1217394109 23129632
-
(2012)
Proc Natl Acad Sci USA
, vol.109
-
-
Luo, W.1
Chang, R.2
Zhong, J.3
Pandey, A.4
Semenza, G.L.5
-
28
-
-
84857042390
-
Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential
-
10.1038/cdd.2011.109 21836617
-
Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential. Heddleston JM, Wu Q, Rivera M, Minhas S, Lathia JD, Sloan AE, Iliopoulos O, Hjelmeland AB, Rich JN, Cell Death Differ 2012 19 428 439 10.1038/cdd.2011.109 21836617
-
(2012)
Cell Death Differ
, vol.19
, pp. 428-439
-
-
Heddleston, J.M.1
Wu, Q.2
Rivera, M.3
Minhas, S.4
Lathia, J.D.5
Sloan, A.E.6
Iliopoulos, O.7
Hjelmeland, A.B.8
Rich, J.N.9
-
29
-
-
46949089391
-
Hypoxia-inducible factor-1α regulates matrix metalloprotease-1 activity in human bone marrow-derived mesenchymal stem cells
-
10.1016/j.febslet.2008.06.033 18588890
-
Hypoxia-inducible factor-1α regulates matrix metalloprotease-1 activity in human bone marrow-derived mesenchymal stem cells. Lin JL, Wang MJ, Lee D, Liang CC, Lin S, FEBS Lett 2008 582 2615 2619 10.1016/j.febslet.2008.06. 033 18588890
-
(2008)
FEBS Lett
, vol.582
, pp. 2615-2619
-
-
Lin, J.L.1
Wang, M.J.2
Lee, D.3
Liang, C.C.4
Lin, S.5
-
30
-
-
13944252559
-
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2α in von Hippel-Lindau renal cell carcinoma
-
10.1038/sj.onc.1208305 15592504
-
Identification of membrane type-1 matrix metalloproteinase as a target of hypoxia-inducible factor-2α in von Hippel-Lindau renal cell carcinoma. Petrella BL, Lohi J, Brinckerhoff CE, Oncogene 2005 24 1043 1052 10.1038/sj.onc.1208305 15592504
-
(2005)
Oncogene
, vol.24
, pp. 1043-1052
-
-
Petrella, B.L.1
Lohi, J.2
Brinckerhoff, C.E.3
-
31
-
-
33646365644
-
Lysyl oxidase is essential for hypoxia-induced metastasis
-
10.1038/nature04695 16642001
-
Lysyl oxidase is essential for hypoxia-induced metastasis. Erler JT, Bennewith EL, Nicolau M, Dornhofer N, Kong C, Le QT, Chi JT, Jeffrey SS, Giaccia AJ, Nature 2006 440 1222 1226 10.1038/nature04695 16642001
-
(2006)
Nature
, vol.440
, pp. 1222-1226
-
-
Erler, J.T.1
Bennewith, E.L.2
Nicolau, M.3
Dornhofer, N.4
Kong, C.5
Le, Q.T.6
Chi, J.T.7
Jeffrey, S.S.8
Giaccia, A.J.9
-
32
-
-
57849100048
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche
-
10.1016/j.ccr.2008.11.012 19111879
-
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. Erler JT, Bennewith KL, Cox TR, Lang G, Bird D, Koong A, Le QT, Giaccia AJ, Cancer Cell 2009 15 35 44 10.1016/j.ccr.2008.11.012 19111879
-
(2009)
Cancer Cell
, vol.15
, pp. 35-44
-
-
Erler, J.T.1
Bennewith, K.L.2
Cox, T.R.3
Lang, G.4
Bird, D.5
Koong, A.6
Le, Q.T.7
Giaccia, A.J.8
-
33
-
-
80053645045
-
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
-
10.1073/pnas.1113483108 21911388
-
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. Wong CC, Gilkes DM, Zhang H, Chen J, Wei H, Chaturvedi P, Fraley SI, Wong CM, Khoo US, Ng IO, Wirtz D, Semenza GL, Proc Natl Acad Sci USA 2011 108 16369 16374 10.1073/pnas.1113483108 21911388
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 16369-16374
-
-
Wong, C.C.1
Gilkes, D.M.2
Zhang, H.3
Chen, J.4
Wei, H.5
Chaturvedi, P.6
Fraley, S.I.7
Wong, C.M.8
Khoo, U.S.9
Ng, I.O.10
Wirtz, D.11
Semenza, G.L.12
-
34
-
-
77954535957
-
Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion
-
10.1038/onc.2010.158 20498644
-
Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion. Santhanam AN, Baker AR, Hegamyer G, Kirschmann DA, Colburn NH, Oncogene 2010 29 3921 3932 10.1038/onc.2010.158 20498644
-
(2010)
Oncogene
, vol.29
, pp. 3921-3932
-
-
Santhanam, A.N.1
Baker, A.R.2
Hegamyer, G.3
Kirschmann, D.A.4
Colburn, N.H.5
-
35
-
-
67650242434
-
ADAMTS1 is a unique hypoxic early response gene expressed by endothelial cells
-
10.1074/jbc.M109.001313 19349275
-
ADAMTS1 is a unique hypoxic early response gene expressed by endothelial cells. Hatipoglu OF, Hirohata S, Cilek MZ, Ogawa H, Miyoshi T, Obika M, Demircan K, Shinohata R, Kusachi S, Nonomiya Y, J Biol Chem 2009 284 16325 16333 10.1074/jbc.M109.001313 19349275
-
(2009)
J Biol Chem
, vol.284
, pp. 16325-16333
-
-
Hatipoglu, O.F.1
Hirohata, S.2
Cilek, M.Z.3
Ogawa, H.4
Miyoshi, T.5
Obika, M.6
Demircan, K.7
Shinohata, R.8
Kusachi, S.9
Nonomiya, Y.10
-
36
-
-
70349774464
-
Role of HIF-1α in the regulation of ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells
-
10.1152/ajplung.90415.2008
-
Role of HIF-1α in the regulation of ACE and ACE2 expression in hypoxic human pulmonary artery smooth muscle cells. Zhang R, Wu Y, Zhao M, Liu C, Zhou L, Shen S, Liao S, Yang K, Li Q, Wan H, Am J Physiol Lung Cell Mo Physiol 2009 297 631 L640 10.1152/ajplung.90415.2008
-
(2009)
Am J Physiol Lung Cell Mo Physiol
, vol.297
-
-
Zhang, R.1
Wu, Y.2
Zhao, M.3
Liu, C.4
Zhou, L.5
Shen, S.6
Liao, S.7
Yang, K.8
Li, Q.9
Wan, H.10
-
37
-
-
79952742302
-
HSulf-1 modulates GFG2- and hypoxia-mediated migration and invasion of breast cancer cells
-
10.1158/0008-5472.CAN-10-3059 21266348
-
HSulf-1 modulates GFG2- and hypoxia-mediated migration and invasion of breast cancer cells. Khurana A, Liu P, Mellone P, Lorenzon L, Vincenzi B, Datta K, Yang B, Linhardt RJ, Lingle W, Chien J, Baldi A, Shridhar V, Cancer Res 2011 71 2152 2161 10.1158/0008-5472.CAN-10-3059 21266348
-
(2011)
Cancer Res
, vol.71
, pp. 2152-2161
-
-
Khurana, A.1
Liu, P.2
Mellone, P.3
Lorenzon, L.4
Vincenzi, B.5
Datta, K.6
Yang, B.7
Linhardt, R.J.8
Lingle, W.9
Chien, J.10
Baldi, A.11
Shridhar, V.12
-
38
-
-
83755178091
-
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
-
10.1073/pnas.1117773108 22106302
-
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Wise DR, Ward PS, Shay JE, Cross JR, Gruber JJ, Sachdeva UM, Platt JM, Dematteo RG, Simon MC, Thompson CB, Proc Natl Acad Sci USA 2011 108 19611 19616 10.1073/pnas.1117773108 22106302
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 19611-19616
-
-
Wise, D.R.1
Ward, P.S.2
Shay, J.E.3
Cross, J.R.4
Gruber, J.J.5
Sachdeva, U.M.6
Platt, J.M.7
Dematteo, R.G.8
Simon, M.C.9
Thompson, C.B.10
-
39
-
-
84864294365
-
HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer
-
10.1093/carcin/bgs142 22467238
-
HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer. Liu Y, Bernauer AM, Yingling CM, Belinsky SA, Carcinogenesis 2012 33 1187 1192 10.1093/carcin/bgs142 22467238
-
(2012)
Carcinogenesis
, vol.33
, pp. 1187-1192
-
-
Liu, Y.1
Bernauer, A.M.2
Yingling, C.M.3
Belinsky, S.A.4
-
40
-
-
0141828145
-
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumor suppressor pVHL
-
10.1038/nature01874 13679920
-
Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumor suppressor pVHL. Staller P, Sulitkova J, Lisztwan J, Moch H, Oakeley EJ, Krek W, Nature 2003 425 307 311 10.1038/nature01874 13679920
-
(2003)
Nature
, vol.425
, pp. 307-311
-
-
Staller, P.1
Sulitkova, J.2
Lisztwan, J.3
Moch, H.4
Oakeley, E.J.5
Krek, W.6
-
41
-
-
84867811185
-
Hypoxia increases CX3CR1 expression via HIF-1 and NF-kB in androgen-independent prostate cancer cells
-
22941344
-
Hypoxia increases CX3CR1 expression via HIF-1 and NF-kB in androgen-independent prostate cancer cells. Xiao LJ, Chen YY, Lin P, Zou HF, Lin F, Zhao LN, Li D, Guo L, Tang JB, Zheng XL, Yu XG, Int J Oncol 2012 41 1827 1836 22941344
-
(2012)
Int J Oncol
, vol.41
, pp. 1827-1836
-
-
Xiao, L.J.1
Chen, Y.Y.2
Lin, P.3
Zou, H.F.4
Lin, F.5
Zhao, L.N.6
Li, D.7
Guo, L.8
Tang, J.B.9
Zheng, X.L.10
Yu, X.G.11
-
42
-
-
84865415804
-
Hypoxia-inducible factor-1α regulates chemotactic migration of pancreatic ductal adenocarcinoma cells through directly transactivating the CX3CR1 gene
-
10.1371/journal.pone.0043399 22952674
-
Hypoxia-inducible factor-1α regulates chemotactic migration of pancreatic ductal adenocarcinoma cells through directly transactivating the CX3CR1 gene. Zhao T, Gao S, Wang X, Liu J, Duan Y, Yuan Z, Sheng J, Li S, Wang F, Yu M, Ren H, Hao J, PLoS One 2012 7 43399 10.1371/journal.pone.0043399 22952674
-
(2012)
PLoS One
, vol.7
, pp. 543399
-
-
Zhao, T.1
Gao, S.2
Wang, X.3
Liu, J.4
Duan, Y.5
Yuan, Z.6
Sheng, J.7
Li, S.8
Wang, F.9
Yu, M.10
Ren, H.11
Hao, J.12
-
43
-
-
44049090235
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
-
10.1073/pnas.0802047105 18427106
-
Notch signaling mediates hypoxia-induced tumor cell migration and invasion. Sahlgren C, Gustafsson MV, Jin S, Poellinger L, Lendahl U, Proc Natl Acad Sci USA 2008 105 6392 6397 10.1073/pnas.0802047105 18427106
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 6392-6397
-
-
Sahlgren, C.1
Gustafsson, M.V.2
Jin, S.3
Poellinger, L.4
Lendahl, U.5
-
44
-
-
61349164240
-
Transcriptional regulation of urokinase-type plasminogen activator receptor by hypoxia-inducible factor 1 is crucial for invasion of pancreatic and liver cancer
-
Transcriptional regulation of urokinase-type plasminogen activator receptor by hypoxia-inducible factor 1 is crucial for invasion of pancreatic and liver cancer. Buchler P, Reber HA, Tomlinson JS, Hankinson O, Kallifatidis G, Friess H, Herr I, Hines OJ, Neoplasia 2009 11 1196 1206
-
(2009)
Neoplasia
, vol.11
, pp. 1196-1206
-
-
Buchler, P.1
Reber, H.A.2
Tomlinson, J.S.3
Hankinson, O.4
Kallifatidis, G.5
Friess, H.6
Herr, I.7
Hines, O.J.8
-
45
-
-
33847373884
-
Molecular regulation of the PAI-1 gene by hypoxia: Contributions of Egr-1, HIF-1α, and C/EBPα
-
10.1096/fj.06-6285com 17197388
-
Molecular regulation of the PAI-1 gene by hypoxia: contributions of Egr-1, HIF-1α, and C/EBPα Liao H, Hyman MC, Lawrence DA, Pinsky DJ, FASEB J 2007 21 935 949 10.1096/fj.06-6285com 17197388
-
(2007)
FASEB J
, vol.21
, pp. 935-949
-
-
Liao, H.1
Hyman, M.C.2
Lawrence, D.A.3
Pinsky, D.J.4
-
46
-
-
77954645380
-
Hypoxia promotes metastasis in human gastric cancer by up-regulating the 67-kDa laminin receptor
-
Hypoxia promotes metastasis in human gastric cancer by up-regulating the 67-kDa laminin receptor. Liu L, Sun L, Zhao P, Yao L, Jin H, Liang S, Wang Y, Zhang D, Pang Y, Shi Y, Chai N, Zhang H, Zhang H, Cancer Sci 2010 10 1653 1660
-
(2010)
Cancer Sci
, vol.10
, pp. 1653-1660
-
-
Liu, L.1
Sun, L.2
Zhao, P.3
Yao, L.4
Jin, H.5
Liang, S.6
Wang, Y.7
Zhang, D.8
Pang, Y.9
Shi, Y.10
Chai, N.11
Zhang, H.12
Zhang, H.13
-
47
-
-
84862815577
-
Hypoxia-inducible factor-1 up-regulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions
-
22487528
-
Hypoxia-inducible factor-1 up-regulates the expression of Toll-like receptor 4 in pancreatic cancer cells under hypoxic conditions. Fan P, Zhang JJ, Wang B, Wu HQ, Zhou SX, Wang CY, Zhang JH, Tian Y, Wu HS, Pancreatology 2012 12 170 178 22487528
-
(2012)
Pancreatology
, vol.12
, pp. 170-178
-
-
Fan, P.1
Zhang, J.J.2
Wang, B.3
Wu, H.Q.4
Zhou, S.X.5
Wang, C.Y.6
Zhang, J.H.7
Tian, Y.8
Wu, H.S.9
-
48
-
-
34250340883
-
Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration.
-
10.1002/ijc.22679 17372907
-
Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration. Eckerich C, Zapf S, Fillbrandt R, Loges S, Westphal M, Lamszus K, Int J Cancer 2007 121 276 283 10.1002/ijc.22679 17372907
-
(2007)
Int J Cancer
, vol.121
, pp. 276-283
-
-
Eckerich, C.1
Zapf, S.2
Fillbrandt, R.3
Loges, S.4
Westphal, M.5
Lamszus, K.6
-
49
-
-
26844481561
-
Up-regulation of c-met protooncogene product expression through hypoxia-inducible factor-1α is involved in trophoblast invasion under low-oxygen tension.
-
10.1210/en.2005-0416 16099863
-
Up-regulation of c-met protooncogene product expression through hypoxia-inducible factor-1α is involved in trophoblast invasion under low-oxygen tension. Hayashi M, Sakata M, Takeda T, Tahara M, Yamamoto T, Okamoto Y, Minekawa R, Isobe A, Ohmichi M, Tasaka K, Murata Y, Endocrinology 2005 146 4682 4689 10.1210/en.2005-0416 16099863
-
(2005)
Endocrinology
, vol.146
, pp. 4682-4689
-
-
Hayashi, M.1
Sakata, M.2
Takeda, T.3
Tahara, M.4
Yamamoto, T.5
Okamoto, Y.6
Minekawa, R.7
Isobe, A.8
Ohmichi, M.9
Tasaka, K.10
Murata, Y.11
-
50
-
-
84855912001
-
Pericyte depletion results in hypoxia-associated epithelial-to- mesenchymal transition and metastasis mediated by Met signaling pathway
-
10.1016/j.ccr.2011.11.024 22264789
-
Pericyte depletion results in hypoxia-associated epithelial-to- mesenchymal transition and metastasis mediated by Met signaling pathway. Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R, Cancer Cell 2012 21 66 81 10.1016/j.ccr.2011.11.024 22264789
-
(2012)
Cancer Cell
, vol.21
, pp. 66-81
-
-
Cooke, V.G.1
Lebleu, V.S.2
Keskin, D.3
Khan, Z.4
O'Connell, J.T.5
Teng, Y.6
Duncan, M.B.7
Xie, L.8
Maeda, G.9
Vong, S.10
Sugimoto, H.11
Rocha, R.M.12
Damascena, A.13
Brentani, R.R.14
Kalluri, R.15
-
51
-
-
41949087400
-
RON tyrosine kinase is a direct target of HIF-1α mediated invasion of breast carcinoma cells
-
RON tyrosine kinase is a direct target of HIF-1α mediated invasion of breast carcinoma cells. Thangasamy A, Rogge J, Ammanamanchi S, J Biol Chem 2009 283 5335 5343
-
(2009)
J Biol Chem
, vol.283
, pp. 5335-5343
-
-
Thangasamy, A.1
Rogge, J.2
Ammanamanchi, S.3
-
52
-
-
68349144691
-
Nitric oxide causes macrophage migration via HIF-1-stimulated small GTPases Cdc42/Rac1
-
10.1016/j.freeradbiomed.2009.06.006 19523512
-
Nitric oxide causes macrophage migration via HIF-1-stimulated small GTPases Cdc42/Rac1. Zhou J, Dehne N, Brune B, Free Radic Biol Med 2009 47 741 749 10.1016/j.freeradbiomed.2009.06.006 19523512
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 741-749
-
-
Zhou, J.1
Dehne, N.2
Brune, B.3
-
53
-
-
84855887513
-
Transcriptional up-regulation of RhoE by hypoxia-inducible epithelial to mesenchymal transition of gastric cancer cells
-
10.1016/j.bbrc.2011.10.065 22037464
-
Transcriptional up-regulation of RhoE by hypoxia-inducible epithelial to mesenchymal transition of gastric cancer cells. Zhou J, Li K, Gu Y, Feng B, Ren G, Zhang L, Wang Y, Nie Y, Fan D, Biochem Biophys Res Commun 2011 415 348 354 10.1016/j.bbrc.2011.10.065 22037464
-
(2011)
Biochem Biophys Res Commun
, vol.415
, pp. 348-354
-
-
Zhou, J.1
Li, K.2
Gu, Y.3
Feng, B.4
Ren, G.5
Zhang, L.6
Wang, Y.7
Nie, Y.8
Fan, D.9
-
54
-
-
71549146268
-
Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion
-
10.1158/0008-5472.CAN-09-1152 19920186
-
Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion. Mardilovich K, Shaw LM, Cancer Res 2009 69 8894 8901 10.1158/0008-5472.CAN-09-1152 19920186
-
(2009)
Cancer Res
, vol.69
, pp. 8894-8901
-
-
Mardilovich, K.1
Shaw, L.M.2
-
55
-
-
0034900493
-
Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix
-
11309343
-
Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix. Airley R, Loncaster J, Davidson S, Bromley M, Roberts S, Patterson A, Hunger R, Stratford I, West C, Clin Cancer Res 2001 7 928 934 11309343
-
(2001)
Clin Cancer Res
, vol.7
, pp. 928-934
-
-
Airley, R.1
Loncaster, J.2
Davidson, S.3
Bromley, M.4
Roberts, S.5
Patterson, A.6
Hunger, R.7
Stratford, I.8
West, C.9
-
56
-
-
0037096732
-
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene
-
12067980
-
Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene. Comerford KM, Wallace TJ, Karhausen J, Louis NA, Montalto MC, Colgan SP, Cancer Res 2002 62 3387 3394 12067980
-
(2002)
Cancer Res
, vol.62
, pp. 3387-3394
-
-
Comerford, K.M.1
Wallace, T.J.2
Karhausen, J.3
Louis, N.A.4
Montalto, M.C.5
Colgan, S.P.6
-
57
-
-
84860212465
-
Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance
-
10.1158/0008-5472.CAN-11-3940 22389449
-
Expression of a truncated active form of VDAC1 in lung cancer associates with hypoxic cell survival and correlates with progression to chemotherapy resistance. Brahimi-Horn MC, Ben-Hall D, Ilie M, Gounon P, Rouleau M, Hofman V, Doyen J, Mari B, Shoshan-Barmatz V, Hofman P, Poussegur J, Mazure NM, Cancer Res 2012 72 2140 2150 10.1158/0008-5472.CAN-11-3940 22389449
-
(2012)
Cancer Res
, vol.72
, pp. 2140-2150
-
-
Brahimi-Horn, M.C.1
Ben-Hall, D.2
Ilie, M.3
Gounon, P.4
Rouleau, M.5
Hofman, V.6
Doyen, J.7
Mari, B.8
Shoshan-Barmatz, V.9
Hofman, P.10
Poussegur, J.11
Mazure, N.M.12
-
58
-
-
84860389759
-
HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
-
21860410
-
HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs. Zhang H, Wong CC, Wei H, Gilkes DM, Korangath P, Chaturvedi P, Schito L, Chen J, Krishnamachary B, Winnard PT Jr, Raman V, Zhen L, Mitzner WA, Sukumar S, Semenza GL, Oncogene 2011 31 1757 1770 21860410
-
(2011)
Oncogene
, vol.31
, pp. 1757-1770
-
-
Zhang, H.1
Wong, C.C.2
Wei, H.3
Gilkes, D.M.4
Korangath, P.5
Chaturvedi, P.6
Schito, L.7
Chen, J.8
Krishnamachary, B.9
Winnard Jr., P.T.10
Raman, V.11
Zhen, L.12
Mitzner, W.A.13
Sukumar, S.14
Semenza, G.L.15
-
59
-
-
57749105319
-
Hypoxia-inducible factor 1α mediated anoikis resistance via suppression α5 integrin
-
10.1158/0008-5472.CAN-08-1839 19074877
-
Hypoxia-inducible factor 1α mediated anoikis resistance via suppression α5 integrin. Rohwer N, Weizel M, Daskalow K, Pfander D, Wiedenmann B, Detjen K, Cramer T, Cancer Res 2008 68 10113 10120 10.1158/0008-5472.CAN-08-1839 19074877
-
(2008)
Cancer Res
, vol.68
, pp. 10113-10120
-
-
Rohwer, N.1
Weizel, M.2
Daskalow, K.3
Pfander, D.4
Wiedenmann, B.5
Detjen, K.6
Cramer, T.7
-
60
-
-
58149332687
-
Regulation of CD151 by hypoxia controls cell adhesion and metastasis in colorectal cancer
-
10.1158/1078-0432.CCR-08-1651 19073968
-
Regulation of CD151 by hypoxia controls cell adhesion and metastasis in colorectal cancer. Chien CW, Lin SC, Lai YY, Lin BW, Lin SC, Lee JC, Tsai SJ, Clin Cancer Res 2008 14 8043 8051 10.1158/1078-0432.CCR-08-1651 19073968
-
(2008)
Clin Cancer Res
, vol.14
, pp. 8043-8051
-
-
Chien, C.W.1
Lin, S.C.2
Lai, Y.Y.3
Lin, B.W.4
Lin, S.C.5
Lee, J.C.6
Tsai, S.J.7
-
61
-
-
84868257627
-
CD24 is an effector of HIF-1 driven primary tumor growth and metastasis
-
10.1158/0008-5472.CAN-11-3666 22926560
-
CD24 is an effector of HIF-1 driven primary tumor growth and metastasis. Thomas S, Harding M, Smith SC, Overdevest JB, Nitz MD, Frierson HF Jr, Tomlins SA, Kristiansen G, Theodorescu D, Cancer Res 2012 72 5600 5612 10.1158/0008-5472.CAN-11-3666 22926560
-
(2012)
Cancer Res
, vol.72
, pp. 5600-5612
-
-
Thomas, S.1
Harding, M.2
Smith, S.C.3
Overdevest, J.B.4
Nitz, M.D.5
Frierson Jr., H.F.6
Tomlins, S.A.7
Kristiansen, G.8
Theodorescu, D.9
-
62
-
-
84865333867
-
Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epithelial solid tumors
-
10.1093/carcin/bgs196 22678117
-
Hypoxia upregulates CD147 through a combined effect of HIF-1α and Sp1 to promote glycolysis and tumor progression in epithelial solid tumors. Ke X, Fei F, Chen Y, Xu L, Zhang Z, Huang Q, Zhang H, Yang H, Chen Z, Xing J, Carcinogenesis 2012 33 1598 1607 10.1093/carcin/bgs196 22678117
-
(2012)
Carcinogenesis
, vol.33
, pp. 1598-1607
-
-
Ke, X.1
Fei, F.2
Chen, Y.3
Xu, L.4
Zhang, Z.5
Huang, Q.6
Zhang, H.7
Yang, H.8
Chen, Z.9
Xing, J.10
-
63
-
-
77955387572
-
Hypoxia inducible factor-1 mediates expression of galectin-1: The potential role in migration/invasion of colorectal cancer cells
-
10.1093/carcin/bgq116 20525878
-
Hypoxia inducible factor-1 mediates expression of galectin-1: the potential role in migration/invasion of colorectal cancer cells. Zhao XY, Chen TT, Xia L, Guo M, Xu Y, Yue F, Jiang Y, Chen GQ, Zhao KW, Carcinogenesis 2010 31 1367 1375 10.1093/carcin/bgq116 20525878
-
(2010)
Carcinogenesis
, vol.31
, pp. 1367-1375
-
-
Zhao, X.Y.1
Chen, T.T.2
Xia, L.3
Guo, M.4
Xu, Y.5
Yue, F.6
Jiang, Y.7
Chen, G.Q.8
Zhao, K.W.9
-
64
-
-
67650999815
-
MUC1, a new hypoxia inducible factor target gene, is an actor in clear renal cell carcinoma tumor progression
-
10.1158/0008-5472.CAN-08-4905 19549898
-
MUC1, a new hypoxia inducible factor target gene, is an actor in clear renal cell carcinoma tumor progression. Aubert S, Fauquette V, Hemon B, Lepoivre R, Briez N, Bernard D, Van Seuningen T, Leroy X, Perrais M, Cancer Res 2009 69 5707 5715 10.1158/0008-5472.CAN-08-4905 19549898
-
(2009)
Cancer Res
, vol.69
, pp. 5707-5715
-
-
Aubert, S.1
Fauquette, V.2
Hemon, B.3
Lepoivre, R.4
Briez, N.5
Bernard, D.6
Van Seuningen, T.7
Leroy, X.8
Perrais, M.9
-
65
-
-
70450263243
-
Hypoxia inducible factor-1-mediated regulation of semaphorin 4D affects tumor growth and vascularity
-
10.1074/jbc.M109.057166 19762474
-
Hypoxia inducible factor-1-mediated regulation of semaphorin 4D affects tumor growth and vascularity. Sun Q, Zhou H, Binmadi NO, Basile JR, J Biol Chem 2009 284 32066 32074 10.1074/jbc.M109.057166 19762474
-
(2009)
J Biol Chem
, vol.284
, pp. 32066-32074
-
-
Sun, Q.1
Zhou, H.2
Binmadi, N.O.3
Basile, J.R.4
-
66
-
-
84859454686
-
Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1
-
10.1073/pnas.1112129109 22411794
-
Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1. Wang Y, Roche O, Xu C, Moriyama EH, Heir P, Chung J, Roos FC, Chen Y, Finak G, Milosevic M, Wilson BC, Teh BT, Park M, Irwin MS, Ohh M, Proc Natl Acad Sci USA 2012 109 4892 4897 10.1073/pnas.1112129109 22411794
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 4892-4897
-
-
Wang, Y.1
Roche, O.2
Xu, C.3
Moriyama, E.H.4
Heir, P.5
Chung, J.6
Roos, F.C.7
Chen, Y.8
Finak, G.9
Milosevic, M.10
Wilson, B.C.11
Teh, B.T.12
Park, M.13
Irwin, M.S.14
Ohh, M.15
-
67
-
-
77952863907
-
Human enhancer of filamentation 1 is a mediator of hypoxia-inducible factor-1α-mediated migration in colorectal carcinoma cells
-
10.1158/0008-5472.CAN-09-2110 20442290
-
Human enhancer of filamentation 1 is a mediator of hypoxia-inducible factor-1α-mediated migration in colorectal carcinoma cells. Kim SH, Xia D, Kim SW, Holla V, Menter DG, Dubois RN, Cancer Res 2010 70 4054 4063 10.1158/0008-5472.CAN-09-2110 20442290
-
(2010)
Cancer Res
, vol.70
, pp. 4054-4063
-
-
Kim, S.H.1
Xia, D.2
Kim, S.W.3
Holla, V.4
Menter, D.G.5
Dubois, R.N.6
-
68
-
-
77956877419
-
Liprin-α4 is a new hypoxia inducible target gene required for maintenance of cell-cell contacts
-
10.1016/j.yexcr.2010.06.022 20599943
-
Liprin-α4 is a new hypoxia inducible target gene required for maintenance of cell-cell contacts. Mattauch S, Sachs M, Behrens J, Exp Cell Res 2010 316 2883 2892 10.1016/j.yexcr.2010.06.022 20599943
-
(2010)
Exp Cell Res
, vol.316
, pp. 2883-2892
-
-
Mattauch, S.1
Sachs, M.2
Behrens, J.3
-
69
-
-
77954516498
-
Regulation of the matricellular proteins CYR61 (CCN1) and NOV (CCN3) by hypoxia-inducible factor-1α and transforming-growth factor-β3 in the human trophoblast
-
10.1210/en.2009-1195 20237132
-
Regulation of the matricellular proteins CYR61 (CCN1) and NOV (CCN3) by hypoxia-inducible factor-1α and transforming-growth factor-β3 in the human trophoblast. Wolf N, Yang W, Dunk CE, Gashaw I, Lye SJ, Ring T, Schmidt M, Winterhager E, Gelihaus A, Endocrinology 2010 151 2835 2845 10.1210/en.2009-1195 20237132
-
(2010)
Endocrinology
, vol.151
, pp. 2835-2845
-
-
Wolf, N.1
Yang, W.2
Dunk, C.E.3
Gashaw, I.4
Lye, S.J.5
Ring, T.6
Schmidt, M.7
Winterhager, E.8
Gelihaus, A.9
-
70
-
-
34248169327
-
Androgen-dependent gene expression of prostate-specific antigen is enhanced synergistically by hypoxia in human prostate cancer cells
-
10.1158/1541-7786.MCR-06-0226 17426252
-
Androgen-dependent gene expression of prostate-specific antigen is enhanced synergistically by hypoxia in human prostate cancer cells. Horii K, Suzuki Y, Kond Y, Akimoto M, Nishimura T, Yamabe Y, Sakaue M, Sano T, Kitagawa T, Himeno S, Imura N, Hara S, Mol Cancer Res 2007 5 383 391 10.1158/1541-7786. MCR-06-0226 17426252
-
(2007)
Mol Cancer Res
, vol.5
, pp. 383-391
-
-
Horii, K.1
Suzuki, Y.2
Kond, Y.3
Akimoto, M.4
Nishimura, T.5
Yamabe, Y.6
Sakaue, M.7
Sano, T.8
Kitagawa, T.9
Himeno, S.10
Imura, N.11
Hara, S.12
-
71
-
-
68549136915
-
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells
-
10.1002/pmic.200800922 19637235
-
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells. Liao SH, Zhao XY, Han YH, Zhang J, Wang LS, Xia L, Zhao KW, Zheng Y, Guo M, Chen GQ, Proteomics 2009 9 3901 3912 10.1002/pmic.200800922 19637235
-
(2009)
Proteomics
, vol.9
, pp. 3901-3912
-
-
Liao, S.H.1
Zhao, X.Y.2
Han, Y.H.3
Zhang, J.4
Wang, L.S.5
Xia, L.6
Zhao, K.W.7
Zheng, Y.8
Guo, M.9
Chen, G.Q.10
-
72
-
-
79953748872
-
Invited review: Decoding the microRNA response to hypoxia
-
10.1007/s00424-010-0910-5 23293481
-
Invited review: decoding the microRNA response to hypoxia. Pocock R, Plfugers Arch-Eur J Physiol 2011 461 307 315 10.1007/s00424-010-0910-5 23293481
-
(2011)
Plfugers Arch - Eur J Physiol
, vol.461
, pp. 307-315
-
-
Pocock, R.1
-
73
-
-
70349168446
-
Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation
-
10.1016/j.molcel.2009.09.006 19782034
-
Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation. Huang X, Ding L, Bennewith KL, Tong RT, Welford SM, Ang KK, Story M, Le QT, Giaccia AJ, Mol Cell 2009 35 856 867 10.1016/j.molcel.2009.09. 006 19782034
-
(2009)
Mol Cell
, vol.35
, pp. 856-867
-
-
Huang, X.1
Ding, L.2
Bennewith, K.L.3
Tong, R.T.4
Welford, S.M.5
Ang, K.K.6
Story, M.7
Le, Q.T.8
Giaccia, A.J.9
-
74
-
-
82455162648
-
Hypoxia-inducible microRNA210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma
-
10.1002/hep.24614 22144109
-
Hypoxia-inducible microRNA210 augments the metastatic potential of tumor cells by targeting vacuole membrane protein 1 in hepatocellular carcinoma. Ying Q, Liang L, Guo W, Zha R, Tian Q, Huang S, Yao J, Ding J, Bao M, Ge C, Yao M, Li J, He X, Hepatology 2011 54 2064 2075 10.1002/hep.24614 22144109
-
(2011)
Hepatology
, vol.54
, pp. 2064-2075
-
-
Ying, Q.1
Liang, L.2
Guo, W.3
Zha, R.4
Tian, Q.5
Huang, S.6
Yao, J.7
Ding, J.8
Bao, M.9
Ge, C.10
Yao, M.11
Li, J.12
He, X.13
-
75
-
-
77952111459
-
MiR-210-micromanager of the hypoxia pathway
-
10.1016/j.molmed.2010.03.004 20434954
-
MiR-210-micromanager of the hypoxia pathway. Huang X, Le QT, Giaccia AJ, Trends Mol Med 2010 16 230 237 10.1016/j.molmed.2010.03.004 20434954
-
(2010)
Trends Mol Med
, vol.16
, pp. 230-237
-
-
Huang, X.1
Le, Q.T.2
Giaccia, A.J.3
-
76
-
-
77952243714
-
Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs
-
10.1038/onc.2010.23 20154725
-
Hypoxia and RAS-signaling pathways converge on, and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs. Loayza-Puch F, Yoshida Y, Matsuzaki T, Takahashi C, Kitayama H, Noda M, Oncogene 2010 29 2638 2648 10.1038/onc.2010.23 20154725
-
(2010)
Oncogene
, vol.29
, pp. 2638-2648
-
-
Loayza-Puch, F.1
Yoshida, Y.2
Matsuzaki, T.3
Takahashi, C.4
Kitayama, H.5
Noda, M.6
-
77
-
-
84857147817
-
Hypoxia-induced down-regulation of microRNA-34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells
-
10.1371/journal.pone.0030771 22363487
-
Hypoxia-induced down-regulation of microRNA-34a promotes EMT by targeting the Notch signaling pathway in tubular epithelial cells. Du R, Sun W, Xia L, Zhao A, Yu Y, Zhao L, Wang H, Huang C, Sun S, PLoS One 2012 7 30771 10.1371/journal.pone.0030771 22363487
-
(2012)
PLoS One
, vol.7
, pp. 530771
-
-
Du, R.1
Sun, W.2
Xia, L.3
Zhao, A.4
Yu, Y.5
Zhao, L.6
Wang, H.7
Huang, C.8
Sun, S.9
-
78
-
-
84873715596
-
HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: A role in myeloid leukemic cell differentiation
-
10.1038/cdd.2012.130
-
HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation. He M, Wang QY, Yin QQ, Tang J, Lu Y, Zhou CX, Duan CW, Hong DL, Tanaka T, Chen GQ, Zhao Q, Cell Death Differ 2012 10.1038/cdd.2012.130
-
(2012)
Cell Death Differ
-
-
He, M.1
Wang, Q.Y.2
Yin, Q.Q.3
Tang, J.4
Lu, Y.5
Zhou, C.X.6
Duan, C.W.7
Hong, D.L.8
Tanaka, T.9
Chen, G.Q.10
Zhao, Q.11
-
79
-
-
84863891322
-
MiR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4
-
10.1158/0008-5472.CAN-12-0667 22593189
-
miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4. Chen HY, Lin YM, Chung HC, Lang YD, Lin CJ, Huang J, Wang WC, Lin FM, Chen Z, Huang HD, Shyy JY, Liang JT, Chen RH, Cancer Res 2012 72 3631 3641 10.1158/0008-5472.CAN-12-0667 22593189
-
(2012)
Cancer Res
, vol.72
, pp. 3631-3641
-
-
Chen, H.Y.1
Lin, Y.M.2
Chung, H.C.3
Lang, Y.D.4
Lin, C.J.5
Huang, J.6
Wang, W.C.7
Lin, F.M.8
Chen, Z.9
Huang, H.D.10
Shyy, J.Y.11
Liang, J.T.12
Chen, R.H.13
-
80
-
-
77950905821
-
P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis
-
10.1073/pnas.0911082107 20308559
-
p53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis. Yamakuchi M, Lotterman CD, Bao C, Hruban RH, Karim B, Mendell JT, Huso D, Lowenstein CJ, Proc Natl Acad Sci USA 2010 107 6334 6339 10.1073/pnas.0911082107 20308559
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 6334-6339
-
-
Yamakuchi, M.1
Lotterman, C.D.2
Bao, C.3
Hruban, R.H.4
Karim, B.5
Mendell, J.T.6
Huso, D.7
Lowenstein, C.J.8
-
81
-
-
84857420013
-
Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs
-
10.1261/rna.027615.111 22282338
-
Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. Voellenkle C, Rooij JV, Guffanti A, Brini E, Fasanaro P, Isaia E, Croft L, David M, Capogrossi MC, Moles A, Felsani A, Martelli F, RNA 2012 18 472 484 10.1261/rna.027615.111 22282338
-
(2012)
RNA
, vol.18
, pp. 472-484
-
-
Voellenkle, C.1
Rooij, J.V.2
Guffanti, A.3
Brini, E.4
Fasanaro, P.5
Isaia, E.6
Croft, L.7
David, M.8
Capogrossi, M.C.9
Moles, A.10
Felsani, A.11
Martelli, F.12
|