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Volumn 63, Issue 11, 2003, Pages 2948-2956

Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CYTOKINE; ENZYME INHIBITOR; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCOPROTEIN GP 130; INTERLEUKIN 6; JANUS KINASE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; STAT3 PROTEIN;

EID: 0038581774     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (250)

References (51)
  • 1
    • 0036233585 scopus 로고    scopus 로고
    • Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
    • O'Shea, J. J., Gadina, M., and Schreiber, R. D. Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell, 109 (Suppl.): S121-131, 2002.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • O'Shea, J.J.1    Gadina, M.2    Schreiber, R.D.3
  • 2
    • 0026770248 scopus 로고
    • Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
    • Schindler, C., Shuai, K., Prezioso, V. R., and Darnell, J. E., Jr. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science (Wash. DC), 257: 809-813, 1992.
    • (1992) Science (Wash. DC) , vol.257 , pp. 809-813
    • Schindler, C.1    Shuai, K.2    Prezioso, V.R.3    Darnell J.E., Jr.4
  • 7
    • 0036731485 scopus 로고    scopus 로고
    • Signalling: Stats: Transcriptional control and biological impact
    • Levy, D. E., and Darnell, J. E. Signalling: Stats: transcriptional control and biological impact. Nat. Rev. Mol. Cell. Biol., 3: 651-662, 2002.
    • (2002) Nat. Rev. Mol. Cell. Biol. , vol.3 , pp. 651-662
    • Levy, D.E.1    Darnell, J.E.2
  • 8
    • 0036256836 scopus 로고    scopus 로고
    • Series introduction. JAK-STAT signaling in human disease
    • Schindler, C. W. Series introduction. JAK-STAT signaling in human disease. J. Clin. Investig., 109: 1133-1137, 2002.
    • (2002) J. Clin. Investig. , vol.109 , pp. 1133-1137
    • Schindler, C.W.1
  • 10
    • 0032523416 scopus 로고    scopus 로고
    • Involvement of SHP-2 in multiple aspects of IL-2 signaling: Evidence for a positive regulatory role
    • Gadina, M. Stancato, L. M., Bacon, C. M., Larner, A. C., and O'Shea, J. J. Involvement of SHP-2 in multiple aspects of IL-2 signaling: evidence for a positive regulatory role. J. Immunol., 160: 4657-4661, 1998.
    • (1998) J. Immunol. , vol.160 , pp. 4657-4661
    • Gadina, M.1    Stancato, L.M.2    Bacon, C.M.3    Larner, A.C.4    O'Shea, J.J.5
  • 11
    • 0030875862 scopus 로고    scopus 로고
    • Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase
    • Zhu, X., Wen, Z., Xu, L. Z., and Darnell, J. E., Jr. Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase. Mol. Cell. Biol., 17: 6618-6623, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6618-6623
    • Zhu, X.1    Wen, Z.2    Xu, L.Z.3    Darnell J.E., Jr.4
  • 12
    • 0030744123 scopus 로고    scopus 로고
    • Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3
    • Wen, Z., and Darnell, J. E., Jr. Mapping of Stat3 serine phosphorylation to a single residue (727) and evidence that serine phosphorylation has no influence on DNA binding of Stat1 and Stat3. Nucleic Acids Res., 25: 2062-2067, 1997.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2062-2067
    • Wen, Z.1    Darnell J.E., Jr.2
  • 13
    • 0033178827 scopus 로고    scopus 로고
    • Extracellular signal-regulated protein kinase (ERK)-dependent and ERK-independent pathways target STAT3 on serine-727 in human neutrophils stimulated by chemotactic factors and cytokines
    • Kuroki, M., and O'Flaherty, J. T. Extracellular signal-regulated protein kinase (ERK)-dependent and ERK- independent pathways target STAT3 on serine-727 in human neutrophils stimulated by chemotactic factors and cytokines. Biochem. J., 341: 691-696, 1999.
    • (1999) Biochem. J. , vol.341 , pp. 691-696
    • Kuroki, M.1    O'Flaherty, J.T.2
  • 14
    • 0030772458 scopus 로고    scopus 로고
    • STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation
    • Chung, J., Uchida, E., Grammer, T. C., and Blenis, J. STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation. Mol. Cell. Biol., 17: 6508-6516, 1997.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 6508-6516
    • Chung, J.1    Uchida, E.2    Grammer, T.C.3    Blenis, J.4
  • 15
    • 0029117304 scopus 로고
    • Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
    • Wen, Z., Zhong, Z., and Darnell, J. E., Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell, 82: 241-250, 1995.
    • (1995) Cell , vol.82 , pp. 241-250
    • Wen, Z.1    Zhong, Z.2    Darnell J.E., Jr.3
  • 16
    • 0033968596 scopus 로고    scopus 로고
    • Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR
    • Yokogami, K., Wakisaka, S., Avruch, J., and Reeves, S. A. Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR. Curr. Biol., 10: 47-50, 2000.
    • (2000) Curr. Biol. , vol.10 , pp. 47-50
    • Yokogami, K.1    Wakisaka, S.2    Avruch, J.3    Reeves, S.A.4
  • 17
    • 0028923658 scopus 로고
    • Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts
    • Watson, C. J., and Miller, W. R. Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts. Br. J. Cancer, 71: 840-844, 1995.
    • (1995) Br. J. Cancer , vol.71 , pp. 840-844
    • Watson, C.J.1    Miller, W.R.2
  • 18
    • 0037124102 scopus 로고    scopus 로고
    • Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines
    • Li, L., and Shaw, P. E. Autocrine-mediated activation of STAT3 correlates with cell proliferation in breast carcinoma lines. J. Biol. Chem., 277: 17397-17405, 2002.
    • (2002) J. Biol. Chem. , vol.277 , pp. 17397-17405
    • Li, L.1    Shaw, P.E.2
  • 20
    • 0031573141 scopus 로고    scopus 로고
    • Constitutive activation of JAKs and STATs in BCR-Abl-expressing cell lines and peripheral blood cells derived from leukemic patients
    • Chai, S. K., Nichols, G. L., and Rothman, P. Constitutive activation of JAKs and STATs in BCR-Abl-expressing cell lines and peripheral blood cells derived from leukemic patients. J. Immunol., 159: 4720-4728, 1997.
    • (1997) J. Immunol. , vol.159 , pp. 4720-4728
    • Chai, S.K.1    Nichols, G.L.2    Rothman, P.3
  • 21
    • 0029784886 scopus 로고    scopus 로고
    • Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines
    • Weber-Nordt, R. M., Egen, C., Wehinger, J., Ludwig, W., Gouilleux-Gruart, V., Mertelsmann, R., and Finke, J. Constitutive activation of STAT proteins in primary lymphoid and myeloid leukemia cells and in Epstein-Barr virus (EBV)-related lymphoma cell lines. Blood, 88: 809-816, 1996.
    • (1996) Blood , vol.88 , pp. 809-816
    • Weber-Nordt, R.M.1    Egen, C.2    Wehinger, J.3    Ludwig, W.4    Gouilleux-Gruart, V.5    Mertelsmann, R.6    Finke, J.7
  • 22
    • 0032852374 scopus 로고    scopus 로고
    • ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells
    • Fernandes, A., Hamburger, A. W., and Gerwin, B. I. ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells. Int. J. Cancer, 83: 564-570, 1999.
    • (1999) Int. J. Cancer , vol.83 , pp. 564-570
    • Fernandes, A.1    Hamburger, A.W.2    Gerwin, B.I.3
  • 24
    • 0013689209 scopus 로고    scopus 로고
    • Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro
    • Grandis, J. R., Drenning, S. D., Chakraborty, A., Zhou, M. Y., Zeng, Q., Pitt, A. S., and Tweardy, D. J. Requirement of Stat3 but not Stat1 activation for epidermal growth factor receptor-mediated cell growth in vitro. J. Clin. Investig., 102: 1385-1392, 1998.
    • (1998) J. Clin. Investig. , vol.102 , pp. 1385-1392
    • Grandis, J.R.1    Drenning, S.D.2    Chakraborty, A.3    Zhou, M.Y.4    Zeng, Q.5    Pitt, A.S.6    Tweardy, D.J.7
  • 25
    • 0035958555 scopus 로고    scopus 로고
    • STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity
    • Ning, Z. Q., Li, J., McGuinness, M., and Arceci, R. J. STAT3 activation is required for Asp(816) mutant c-Kit induced tumorigenicity. Oncogene, 20: 4528-4536, 2001.
    • (2001) Oncogene , vol.20 , pp. 4528-4536
    • Ning, Z.Q.1    Li, J.2    McGuinness, M.3    Arceci, R.J.4
  • 26
    • 0031025240 scopus 로고    scopus 로고
    • Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells
    • Sartor, C. I., Dziubinski, M. L., Yu, C. L., Jove, R., and Ethier, S. P. Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells. Cancer Res., 57: 978-987, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 978-987
    • Sartor, C.I.1    Dziubinski, M.L.2    Yu, C.L.3    Jove, R.4    Ethier, S.P.5
  • 28
    • 0034021563 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-mediated stat3 signaling blocks apoptosis in head and neck cancer
    • Grandis, J. R., Zeng, Q., and Drenning, S. D. Epidermal growth factor receptor-mediated stat3 signaling blocks apoptosis in head and neck cancer. Laryngoscope, 110: 868-874, 2000.
    • (2000) Laryngoscope , vol.110 , pp. 868-874
    • Grandis, J.R.1    Zeng, Q.2    Drenning, S.D.3
  • 29
    • 0030927973 scopus 로고    scopus 로고
    • Epidermal growth factor receptor immuno-reactivity in human laryngeal squamous cell carcinoma
    • Lee, C. S., Redshaw, A., and Boag, G. Epidermal growth factor receptor immuno-reactivity in human laryngeal squamous cell carcinoma. Pathology, 29: 251-254, 1997.
    • (1997) Pathology , vol.29 , pp. 251-254
    • Lee, C.S.1    Redshaw, A.2    Boag, G.3
  • 32
    • 0027524082 scopus 로고
    • Oncogenes in head and neck cancer
    • Irish, J. C., and Bernstein, A. Oncogenes in head and neck cancer. Laryngoscope, 103: 42-52, 1993.
    • (1993) Laryngoscope , vol.103 , pp. 42-52
    • Irish, J.C.1    Bernstein, A.2
  • 33
    • 0026324504 scopus 로고
    • A comparison of epidermal growth factor receptor (EGFR) and c-erbB-2 oncogene expression in head and neck squamous cell carcinomas
    • Kearsley, J. H., Leonard, J. H., Walsh, M. D., and Wright, G. R. A comparison of epidermal growth factor receptor (EGFR) and c-erbB-2 oncogene expression in head and neck squamous cell carcinomas. Pathology, 23: 189-194, 1991.
    • (1991) Pathology , vol.23 , pp. 189-194
    • Kearsley, J.H.1    Leonard, J.H.2    Walsh, M.D.3    Wright, G.R.4
  • 36
    • 0031468604 scopus 로고    scopus 로고
    • Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck
    • Patel, V., Jakus, J., Harris, C. M., Ensley, J. F., Robbins, K. C., and Yeudall, W. A. Altered expression and activity of G1/S cyclins and cyclin-dependent kinases characterize squamous cell carcinomas of the head and neck. Int. J. Cancer, 73: 551-555, 1997.
    • (1997) Int. J. Cancer , vol.73 , pp. 551-555
    • Patel, V.1    Jakus, J.2    Harris, C.M.3    Ensley, J.F.4    Robbins, K.C.5    Yeudall, W.A.6
  • 39
    • 0028245609 scopus 로고
    • Cytokines that associate with the signal transducer gp130 activate the interferon-induced transcription factor p91 by tyrosine phosphorylation
    • Feldman, G. M., Petricoin, E. F., III, David, M., Larner, A. C., and Finbloom, D. S. Cytokines that associate with the signal transducer gp130 activate the interferon-induced transcription factor p91 by tyrosine phosphorylation. J. Biol. Chem., 269: 10747-10752, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10747-10752
    • Feldman, G.M.1    Petricoin E.F. III2    David, M.3    Larner, A.C.4    Finbloom, D.S.5
  • 40
    • 85047698100 scopus 로고    scopus 로고
    • Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells
    • Burke, W. M., Jin, X., Lin, H. J., Huang, M., Liu, R., Reynolds, R. K., and Lin, J. Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells. Oncogene, 20: 7925-7934, 2001.
    • (2001) Oncogene , vol.20 , pp. 7925-7934
    • Burke, W.M.1    Jin, X.2    Lin, H.J.3    Huang, M.4    Liu, R.5    Reynolds, R.K.6    Lin, J.7
  • 44
    • 0034658499 scopus 로고    scopus 로고
    • STAT signaling in head and neck cancer
    • Song, J. I., and Grandis, J. R. STAT signaling in head and neck cancer. Oncogene, 19: 2489-2495, 2000.
    • (2000) Oncogene , vol.19 , pp. 2489-2495
    • Song, J.I.1    Grandis, J.R.2
  • 45
    • 0006603039 scopus 로고    scopus 로고
    • Serine phosphorylation and negative regulation of Stat3 by JNK
    • Lim, C. P., and Cao, X. Serine phosphorylation and negative regulation of Stat3 by JNK. J. Biol. Chem., 274: 31055-31061, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 31055-31061
    • Lim, C.P.1    Cao, X.2
  • 47
    • 0027034108 scopus 로고
    • Cytokine expression by head and neck squamous cell carcinomas
    • Mann, E. A., Spiro, J. D., Chen, L. L., and Kreutzer, D. L. Cytokine expression by head and neck squamous cell carcinomas. Am. J. Surg., 164: 567-573, 1992.
    • (1992) Am. J. Surg. , vol.164 , pp. 567-573
    • Mann, E.A.1    Spiro, J.D.2    Chen, L.L.3    Kreutzer, D.L.4
  • 48
    • 0032527621 scopus 로고    scopus 로고
    • Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens
    • Woods, K. V., El-Naggar, A., Clayman, G. L., and Grimm, E. A. Variable expression of cytokines in human head and neck squamous cell carcinoma cell lines and consistent expression in surgical specimens. Cancer Res., 58: 3132-3141, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 3132-3141
    • Woods, K.V.1    El-Naggar, A.2    Clayman, G.L.3    Grimm, E.A.4
  • 49
    • 0032168152 scopus 로고    scopus 로고
    • Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
    • Heinrich, P. C., Behrmann, I., Muller-Newen, G., Schaper, F., and Graeve, L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J., 334 (Pt. 2): 297-314, 1998.
    • (1998) Biochem. J. , vol.334 , Issue.PART 2 , pp. 297-314
    • Heinrich, P.C.1    Behrmann, I.2    Muller-Newen, G.3    Schaper, F.4    Graeve, L.5
  • 50
    • 0035026164 scopus 로고    scopus 로고
    • Targeting growth factor receptors: Integration of novel therapeutics in the management of head and neck cancer
    • Lango, M. N., Shin, D. M., and Grandis, J. R. Targeting growth factor receptors: integration of novel therapeutics in the management of head and neck cancer. Curr. Opin. Oncol., 13: 168-175, 2001.
    • (2001) Curr. Opin. Oncol. , vol.13 , pp. 168-175
    • Lango, M.N.1    Shin, D.M.2    Grandis, J.R.3
  • 51
    • 0036500831 scopus 로고    scopus 로고
    • Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: A new paradigm for cancer therapy
    • Herbst, R. S., and Shin, D. M. Monoclonal antibodies to target epidermal growth factor receptor-positive tumors: a new paradigm for cancer therapy. Cancer, 94: 1593-1611, 2002.
    • (2002) Cancer , vol.94 , pp. 1593-1611
    • Herbst, R.S.1    Shin, D.M.2


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