-
1
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, et al. 1999. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257:79-83.
-
(1999)
Biochem Biophys Res Commun
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
Hotta, K.7
Shimomura, I.8
Nakamura, T.9
Miyaoka, K.10
-
2
-
-
0033667705
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
-
Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, Manning BS, Miroux B, Couplan E, Alves-Guerra MC, Goubern M, Surwit R, et al. 2000. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genetics 26:435-39.
-
(2000)
Nat Genetics
, vol.26
, pp. 435-439
-
-
Arsenijevic, D.1
Onuma, H.2
Pecqueur, C.3
Raimbault, S.4
Manning, B.S.5
Miroux, B.6
Couplan, E.7
Alves-Guerra, M.C.8
Goubern, M.9
Surwit, R.10
-
3
-
-
0034881391
-
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
-
Berg AH, Combs TP, Du X, Brownlee M, Scherer PE. 2001. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action. Nat Med 7:947-53.
-
(2001)
Nat Med
, vol.7
, pp. 947-953
-
-
Berg, A.H.1
Combs2
TP, D.X.3
Brownlee, M.4
Scherer, P.E.5
-
4
-
-
1642525769
-
Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages
-
Bosco MC, Puppo M, Pastorino S, Mi Z, Melillo G, Massazza S, Rapisarda A, Varesio L. 2004. Hypoxia selectively inhibits monocyte chemoattractant protein-1 production by macrophages. J Immunol 172:1681-90.
-
(2004)
J Immunol
, vol.172
, pp. 1681-1690
-
-
Bosco, M.C.1
Puppo, M.2
Pastorino, S.3
Mi, Z.4
Melillo, G.5
Massazza, S.6
Rapisarda, A.7
Varesio, L.8
-
5
-
-
34447504549
-
Oxygen, a source of life and stress
-
Brahimi-Horn MC, Pouysségur J. 2007. Oxygen, a source of life and stress. FEBS Lett 581:3582-91.
-
(2007)
FEBS Lett
, vol.581
, pp. 3582-3591
-
-
Brahimi-Horn, M.C.1
Pouysségur, J.2
-
7
-
-
24944454234
-
Release of C-reactive protein in response to inflammatory cytokines by human adipocytes: Linking obesity to vascular inflammation
-
Calabro P, Chang DW, Willerson JT, Yeh ET. 2005. Release of C-reactive protein in response to inflammatory cytokines by human adipocytes: linking obesity to vascular inflammation. J Am Coll Cardiol 46:1112-23.
-
(2005)
J Am Coll Cardiol
, vol.46
, pp. 1112-1123
-
-
Calabro, P.1
Chang, D.W.2
Willerson, J.T.3
Yeh, E.T.4
-
8
-
-
22744443177
-
Leptin: A proliferative factor for breast cancer?: Study on human ductal carcinoma
-
Caldefie-Chezet F, Damez M, de Latour M, Konska G, Mishellani F, Fusillier C, Guerry M, Penault-Llorca F, Guillot J, Vasson M-P. 2005. Leptin: A proliferative factor for breast cancer?: Study on human ductal carcinoma. Biochem Biophys Res Commun 334:737-41.
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 737-741
-
-
Caldefie-Chezet, F.1
Damez, M.2
de Latour, M.3
Konska, G.4
Mishellani, F.5
Fusillier, C.6
Guerry, M.7
Penault-Llorca, F.8
Guillot, J.9
Vasson, M.-P.10
-
9
-
-
4644329647
-
mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: A mechanism for hypoxia-dependent effect
-
Carriere A, Carmona M-C, Fernandez Y, Rigoulet M, Wenger RH, Penicaud L, Casteilla L. 2004. mitochondrial reactive oxygen species control the transcription factor CHOP-10/GADD153 and adipocyte differentiation: a mechanism for hypoxia-dependent effect. J Biol Chem 279:40462-69.
-
(2004)
J Biol Chem
, vol.279
, pp. 40462-40469
-
-
Carriere, A.1
Carmona, M.-C.2
Fernandez, Y.3
Rigoulet, M.4
Wenger, R.H.5
Penicaud, L.6
Casteilla, L.7
-
10
-
-
31444447850
-
Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes
-
Chen B, Lam KSL, Wang Y, Wu D, Lam MC, Shen J, Wong L, Hoo RLC, Zhang J, Xu A. 2006. Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes. Biochem Biophys Res Commun 341:549-56.
-
(2006)
Biochem Biophys Res Commun
, vol.341
, pp. 549-556
-
-
Chen, B.1
Lam, K.S.L.2
Wang, Y.3
Wu, D.4
Lam, M.C.5
Shen, J.6
Wong, L.7
Hoo, R.L.C.8
Zhang, J.9
Xu, A.10
-
11
-
-
33751235259
-
preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes
-
Chung S, LaPoint K, Martinez K, Kennedy A, Boysen Sandberg M, McIntosh MK. 2006. preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes. Endocrinology 147:5340-51.
-
(2006)
Endocrinology
, vol.147
, pp. 5340-5351
-
-
Chung, S.1
LaPoint, K.2
Martinez, K.3
Kennedy, A.4
Boysen Sandberg, M.5
McIntosh, M.K.6
-
12
-
-
0023663615
-
Adipsin: A circulating serine protease homolog secreted by adipose tissue and sciatic nerve
-
Cook KS, Min HY, Johnson D, Chaplinsky RJ, Flier JS, Hunt CR, Spiegelman BM. 1987. Adipsin: a circulating serine protease homolog secreted by adipose tissue and sciatic nerve. Science 237:402-5.
-
(1987)
Science
, vol.237
, pp. 402-405
-
-
Cook, K.S.1
Min, H.Y.2
Johnson, D.3
Chaplinsky, R.J.4
Flier, J.S.5
Hunt, C.R.6
Spiegelman, B.M.7
-
13
-
-
0033007024
-
A role for preadipocytes as macrophage-like cells
-
Cousin B, Munoz O, Andre M, Fontanilles AM, Dani C, Cousin JL, Laharrague P, Casteilla L, Penicaud L. 1999. A role for preadipocytes as macrophage-like cells. FASEB J 13:305-12.
-
(1999)
FASEB J
, vol.13
, pp. 305-312
-
-
Cousin, B.1
Munoz, O.2
Andre, M.3
Fontanilles, A.M.4
Dani, C.5
Cousin, J.L.6
Laharrague, P.7
Casteilla, L.8
Penicaud, L.9
-
15
-
-
0038492596
-
Induction of T-type calcium channel gene expression by chronic hypoxia
-
Del Toro R, Levitsky KL, López-Barneo J, Chiara MD. 2003. Induction of T-type calcium channel gene expression by chronic hypoxia. J Biol Chem 278:22316-24.
-
(2003)
J Biol Chem
, vol.278
, pp. 22316-22324
-
-
Del Toro, R.1
Levitsky, K.L.2
López-Barneo, J.3
Chiara, M.D.4
-
16
-
-
0015040364
-
Relationship of adipose tissue blood flow to fat cell size and number
-
Girolamo M, Skinner NS, Jr., Hanley HG, Sachs RG. 1971. Relationship of adipose tissue blood flow to fat cell size and number. Am J Physiol 220:932-7.
-
(1971)
Am J Physiol
, vol.220
, pp. 932-937
-
-
Girolamo, M.1
Skinner Jr., N.S.2
Hanley, H.G.3
Sachs, R.G.4
-
17
-
-
0035988689
-
Metallothionein gene expression in human adipose tissue from lean and obese subjects
-
Do MS, Nam SY, Hong SE, Kim KW, Duncan JS, Beattie JH, Trayhurn P. 2002. Metallothionein gene expression in human adipose tissue from lean and obese subjects. Horm Metab Res 34:348-51.
-
(2002)
Horm Metab Res
, vol.34
, pp. 348-351
-
-
Do, M.S.1
Nam, S.Y.2
Hong, S.E.3
Kim, K.W.4
Duncan, J.S.5
Beattie, J.H.6
Trayhurn, P.7
-
18
-
-
10744220710
-
Human adipocytes secrete mineralocorticoid-releasing factors
-
Ehrhart-Bornstein M, Lamounier-Zepter V, Schraven A, Langenbach J, Willenberg HS, Barthel A, Hauner H, McCann SM, Scherbaum WA, Bornstein SR. 2003. Human adipocytes secrete mineralocorticoid-releasing factors. Proc Natl Acad Sci USA 100:14211-16.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14211-14216
-
-
Ehrhart-Bornstein, M.1
Lamounier-Zepter, V.2
Schraven, A.3
Langenbach, J.4
Willenberg, H.S.5
Barthel, A.6
Hauner, H.7
McCann, S.M.8
Scherbaum, W.A.9
Bornstein, S.R.10
-
19
-
-
0035160270
-
Tissue oxygen tension and brain sensitivity to hypoxia
-
Erecinska M, Silver IA. 2001. Tissue oxygen tension and brain sensitivity to hypoxia. Respir Physiol 128:263-76.
-
(2001)
Respir Physiol
, vol.128
, pp. 263-276
-
-
Erecinska, M.1
Silver, I.A.2
-
20
-
-
2042480671
-
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
-
Fain JN, Madan AK, Hiler ML, Cheema P, Bahouth SW. 2004. Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans. Endocrinology 145:2273-82.
-
(2004)
Endocrinology
, vol.145
, pp. 2273-2282
-
-
Fain, J.N.1
Madan, A.K.2
Hiler, M.L.3
Cheema, P.4
Bahouth, S.W.5
-
21
-
-
33846201363
-
Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells
-
Fain JN. 2006. Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm 74:443-77.
-
(2006)
Vitam Horm
, vol.74
, pp. 443-477
-
-
Fain, J.N.1
-
22
-
-
21344460456
-
Tissue oxygenation in obese and non-obese patients during laparoscopy
-
Fleischmann E, Kurz A, Niedermayr M, Schebesta K, Kimberger O, Sessler DI, Kabon B, Prager G. 2005. Tissue oxygenation in obese and non-obese patients during laparoscopy. Obesity Surg 15:813-19.
-
(2005)
Obesity Surg
, vol.15
, pp. 813-819
-
-
Fleischmann, E.1
Kurz, A.2
Niedermayr, M.3
Schebesta, K.4
Kimberger, O.5
Sessler, D.I.6
Kabon, B.7
Prager, G.8
-
24
-
-
8144228566
-
Why do cancers have high aerobic glycolysis?
-
Gatenby RA, Gillies RJ. 2004. Why do cancers have high aerobic glycolysis? Nat Rev Cancer 4:891-99.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 891-899
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
25
-
-
0035946468
-
Chemokines control fat accumulation and leptin secretion by cultured human adipocytes
-
Gerhardt CC, Romero IA, Cancello R, Camoin L, Strösberg AD. 2001. Chemokines control fat accumulation and leptin secretion by cultured human adipocytes. Mol Cell Endocrinol 175:81-92.
-
(2001)
Mol Cell Endocrinol
, vol.175
, pp. 81-92
-
-
Gerhardt, C.C.1
Romero, I.A.2
Cancello, R.3
Camoin, L.4
Strösberg, A.D.5
-
26
-
-
37149011809
-
HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes
-
Glassford AJ, Yue P, Sheikh AY, Chun HJ, Zarafshar S, Chan DA, Reaven GM, Quertermous T, Tsao PS. 2007. HIF-1 regulates hypoxia- and insulin-induced expression of apelin in adipocytes. Am J Physiol Endocrinol Metab 293:E1590-96.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Glassford, A.J.1
Yue, P.2
Sheikh, A.Y.3
Chun, H.J.4
Zarafshar, S.5
Chan, D.A.6
Reaven, G.M.7
Quertermous, T.8
Tsao, P.S.9
-
27
-
-
34948836879
-
Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism
-
Goralski KB, McCarthy TC, Hanniman EA, Zabel BA, Butcher EC, Parlee SD, Muruganandan S, Sinal CJ. 2007. Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism. J Biol Chem 282:28175-88.
-
(2007)
J Biol Chem
, vol.282
, pp. 28175-28188
-
-
Goralski, K.B.1
McCarthy, T.C.2
Hanniman, E.A.3
Zabel, B.A.4
Butcher, E.C.5
Parlee, S.D.6
Muruganandan, S.7
Sinal, C.J.8
-
28
-
-
0347990602
-
Stimulation of lipolysis by tumor necrosis factor-α in 3T3-L1 adipocytes is glucose dependent: Implications for long-term regulation of lipolysis
-
Green A, Rumberger JM, Stuart CA, Ruhoff MS. 2004. Stimulation of lipolysis by tumor necrosis factor-α in 3T3-L1 adipocytes is glucose dependent: implications for long-term regulation of lipolysis. Diabetes 53:74-81.
-
(2004)
Diabetes
, vol.53
, pp. 74-81
-
-
Green, A.1
Rumberger, J.M.2
Stuart, C.A.3
Ruhoff, M.S.4
-
29
-
-
34548419344
-
Adipocyte stress: The endoplasmic reticulum and metabolic disease
-
Gregor MF, Hotamisligil GS. 2007. Adipocyte stress: the endoplasmic reticulum and metabolic disease. J Lipid Res 48:1905-14.
-
(2007)
J Lipid Res
, vol.48
, pp. 1905-1914
-
-
Gregor, M.F.1
Hotamisligil, G.S.2
-
30
-
-
0028356449
-
Glucose transport activity in skeletal muscles from transgenic mice overexpressing GLUT1. Increased basal transport is associated with a defective response to diverse stimuli that activate GLUT4
-
Gulve EA, Ren JM, Marshall BA, Gao J, Hansen PA, Holloszy JO, Mueckler M. 1994. Glucose transport activity in skeletal muscles from transgenic mice overexpressing GLUT1. Increased basal transport is associated with a defective response to diverse stimuli that activate GLUT4. J Biol Chem 269:18366-70.
-
(1994)
J Biol Chem
, vol.269
, pp. 18366-18370
-
-
Gulve, E.A.1
Ren, J.M.2
Marshall, B.A.3
Gao, J.4
Hansen, P.A.5
Holloszy, J.O.6
Mueckler, M.7
-
31
-
-
4744361664
-
Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice
-
Harkins JM, Moustaid-Moussa N, Chung Y-J, Penner KM, Pestka JJ, North CM, Claycombe KJ. 2004. Expression of interleukin-6 is greater in preadipocytes than in adipocytes of 3T3-L1 cells and C57BL/6J and ob/ob mice. J Nutr 134:2673-77.
-
(2004)
J Nutr
, vol.134
, pp. 2673-2677
-
-
Harkins, J.M.1
Moustaid-Moussa, N.2
Chung, Y.-J.3
Penner, K.M.4
Pestka, J.J.5
North, C.M.6
Claycombe, K.J.7
-
32
-
-
0035502460
-
The biology of white adipocyte proliferation
-
Hausman DB, Di Girolamo M, Bartness TJ, Hausman GJ, Martin RJ. 2001. The biology of white adipocyte proliferation. Obesity Rev 2:239-54.
-
(2001)
Obesity Rev
, vol.2
, pp. 239-254
-
-
Hausman, D.B.1
Di Girolamo, M.2
Bartness, T.J.3
Hausman, G.J.4
Martin, R.J.5
-
34
-
-
34047119110
-
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
-
Hosogai N, Fukuhara A, Oshima K, Miyata Y, Tanaka S, Segawa K, Furukawa S, Tochino Y, Komuro R, Matsuda M, et al. 2007. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation. Diabetes 56:901-11.
-
(2007)
Diabetes
, vol.56
, pp. 901-911
-
-
Hosogai, N.1
Fukuhara, A.2
Oshima, K.3
Miyata, Y.4
Tanaka, S.5
Segawa, K.6
Furukawa, S.7
Tochino, Y.8
Komuro, R.9
Matsuda, M.10
-
35
-
-
0027459878
-
Adipose expression of tumor necrosis factor-alpha - direct role in obesity-linked insulin resistance
-
Hotamisligil GS, Shargill NS, Spiegelman BM. 1993. Adipose expression of tumor necrosis factor-alpha - direct role in obesity-linked insulin resistance. Science 259:87-91.
-
(1993)
Science
, vol.259
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
36
-
-
33845866857
-
Inflammation and metabolic disorders
-
Hotamisligil GS. 2006. Inflammation and metabolic disorders. Nature 444:860-67.
-
(2006)
Nature
, vol.444
, pp. 860-867
-
-
Hotamisligil, G.S.1
-
37
-
-
33645860825
-
Reactive oxygen species have a causal role in multiple forms of insulin resistance
-
Houstis N, Rosen ED, Lander ES. 2006. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440:944-48.
-
(2006)
Nature
, vol.440
, pp. 944-948
-
-
Houstis, N.1
Rosen, E.D.2
Lander, E.S.3
-
38
-
-
34247356154
-
Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity
-
Iiyori N, Alonso LC, Li J, Sanders MH, Garcia-Ocana A, O'Doherty RM, Polotsky VY, O'Donnell CP. 2007. Intermittent hypoxia causes insulin resistance in lean mice independent of autonomic activity. Am J Respir Crit Care Med 175:851-57.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 851-857
-
-
Iiyori, N.1
Alonso, L.C.2
Li, J.3
Sanders, M.H.4
Garcia-Ocana, A.5
O'Doherty, R.M.6
Polotsky, V.Y.7
O'Donnell, C.P.8
-
39
-
-
0036499482
-
Obstructive sleep apnea is independently associated with insulin resistance
-
Ip MS, Lam B, Ng MM, Lam WK, Tsang KW, Lam KS. 2002. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med 165:670-76.
-
(2002)
Am J Respir Crit Care Med
, vol.165
, pp. 670-676
-
-
Ip, M.S.1
Lam, B.2
Ng, M.M.3
Lam, W.K.4
Tsang, K.W.5
Lam, K.S.6
-
40
-
-
0035917313
-
HIFα targeted for VHL-mediated destruction by proline hydroxylation: Implications for O2 sensing
-
Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, Salic A, Asara JM, Lane WS, Kaelin Jr WG. 2001. HIFα targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science 292:464-68.
-
(2001)
Science
, vol.292
, pp. 464-468
-
-
Ivan, M.1
Kondo, K.2
Yang, H.3
Kim, W.4
Valiando, J.5
Ohh, M.6
Salic, A.7
Asara, J.M.8
Lane, W.S.9
Kaelin Jr, W.G.10
-
41
-
-
0035917808
-
2-regulated prolyl hydroxylation
-
2-regulated prolyl hydroxylation. Science 292:468-72.
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
Mole, D.R.2
Tian, Y.M.3
Wilson, M.I.4
Gielbert, J.5
Gaskell, S.J.6
Kriegsheim, A.7
Hebestreit, H.F.8
Mukherji, M.9
Schofield, C.J.10
Maxwell, P.H.11
Pugh, C.W.12
Ratcliffe, P.J.13
-
42
-
-
1642499314
-
Obesity decreases perioperative tissue oxygenation
-
Kabon B, Nagele A, Reddy D, Eagon C, Fleshman JW, Sessler DI, Kurz A. 2004. Obesity decreases perioperative tissue oxygenation. Anesthesiol 100:274-80.
-
(2004)
Anesthesiol
, vol.100
, pp. 274-280
-
-
Kabon, B.1
Nagele, A.2
Reddy, D.3
Eagon, C.4
Fleshman, J.W.5
Sessler, D.I.6
Kurz, A.7
-
43
-
-
37549040190
-
The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS
-
Kadowaki T, Yamauchi T, Kubota N. 2008. The physiological and pathophysiological role of adiponectin and adiponectin receptors in the peripheral tissues and CNS. FEBS Lett 582:74-80.
-
(2008)
FEBS Lett
, vol.582
, pp. 74-80
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
-
44
-
-
0036320410
-
Impaired Postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity
-
Karpe F, Fielding BA, Ilic V, Macdonald IA, Summers LKM, Frayn KN. 2002. Impaired Postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity. Diabetes 51:2467-73.
-
(2002)
Diabetes
, vol.51
, pp. 2467-2473
-
-
Karpe, F.1
Fielding, B.A.2
Ilic, V.3
Macdonald, I.A.4
Summers, L.K.M.5
Frayn, K.N.6
-
46
-
-
21344442127
-
Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner
-
Kim KH, Song MJ, Chung J, Park H, Kim JB. 2005. Hypoxia inhibits adipocyte differentiation in a HDAC-independent manner. Biochem Biophys Res Commun 333:1178-84.
-
(2005)
Biochem Biophys Res Commun
, vol.333
, pp. 1178-1184
-
-
Kim, K.H.1
Song, M.J.2
Chung, J.3
Park, H.4
Kim, J.B.5
-
47
-
-
0034611791
-
Obesity as a medical problem
-
Kopelman PG. 2000. Obesity as a medical problem. Nature 404:635-43.
-
(2000)
Nature
, vol.404
, pp. 635-643
-
-
Kopelman, P.G.1
-
48
-
-
0036837864
-
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α
-
Koumenis C, Naczki C, Koritzinsky M, Rastani S, Diehl A, Sonenberg N, Koromilas A, Wouters BG. 2002. Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2α. Mol Cell Biol 22:7405-16.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7405-7416
-
-
Koumenis, C.1
Naczki, C.2
Koritzinsky, M.3
Rastani, S.4
Diehl, A.5
Sonenberg, N.6
Koromilas, A.7
Wouters, B.G.8
-
49
-
-
0033405817
-
Macrophage responses to hypoxia: Relevance to disease mechanisms
-
Lewis JS, Lee JA, Underwood JC, Harris AL, Lewis CE. 1999. Macrophage responses to hypoxia: relevance to disease mechanisms. J Leukoc Biol 66:889-900.
-
(1999)
J Leukoc Biol
, vol.66
, pp. 889-900
-
-
Lewis, J.S.1
Lee, J.A.2
Underwood, J.C.3
Harris, A.L.4
Lewis, C.E.5
-
50
-
-
33750038847
-
Differentiation arrest by hypoxia
-
Lin Q, Lee Y-J, Yun Z. 2006. Differentiation arrest by hypoxia. J Biol Chem 281:30678-83.
-
(2006)
J Biol Chem
, vol.281
, pp. 30678-30683
-
-
Lin, Q.1
Lee, Y.-J.2
Yun, Z.3
-
51
-
-
0142057126
-
-
Lolmède K, Durand de Saint Front V, Galitzky J, Lafontan M, Bouloumié A. 2003. Effects of hypoxia on the expression of proangiogenic factors in differentiated 3T3-F442A adipocytes. Int J Obesity 27:1187-95.
-
Lolmède K, Durand de Saint Front V, Galitzky J, Lafontan M, Bouloumié A. 2003. Effects of hypoxia on the expression of proangiogenic factors in differentiated 3T3-F442A adipocytes. Int J Obesity 27:1187-95.
-
-
-
-
52
-
-
1342283030
-
Regulation of oxygen sensing by ion channels
-
López-Barneo J, del Toro R, Levitsky KL, Chiara MD, Ortega-Sáenz P. 2004. Regulation of oxygen sensing by ion channels. J Appl Physiol 96:1187-95.
-
(2004)
J Appl Physiol
, vol.96
, pp. 1187-1195
-
-
López-Barneo, J.1
del Toro, R.2
Levitsky, K.L.3
Chiara, M.D.4
Ortega-Sáenz, P.5
-
53
-
-
35148901589
-
Inflammation may modulate IL-6 and C-reactive protein gene expression in the adipose tissue: The role of IL-6 cell membrane receptor
-
Memoli B, Procino A, Calabro P, Esposito P, Grandaliano G, Pertosa G, Prete MD, Andreucci M, Lillo SD, Ferulano G, et al. 2007. Inflammation may modulate IL-6 and C-reactive protein gene expression in the adipose tissue: the role of IL-6 cell membrane receptor. Am J Physiol Endocrinol Metab 293:E1030-35.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Memoli, B.1
Procino, A.2
Calabro, P.3
Esposito, P.4
Grandaliano, G.5
Pertosa, G.6
Prete, M.D.7
Andreucci, M.8
Lillo, S.D.9
Ferulano, G.10
-
54
-
-
35248884457
-
Cellular mechanisms associated with intermittent hypoxia
-
Nanduri N, Prabhakar NR. 2007. Cellular mechanisms associated with intermittent hypoxia. Essays Biochem 43:91-104.
-
(2007)
Essays Biochem
, vol.43
, pp. 91-104
-
-
Nanduri, N.1
Prabhakar, N.R.2
-
55
-
-
34948813665
-
Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice
-
Nomiyama T, Perez-Tilve D, Ogawa D, Gizard F, Zhao Y, Heywood EB, Jones KL, Kawamori R, Cassis LA, Tschöp MH, et al. 2007. Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice. J Clin Invest 117:2877-88.
-
(2007)
J Clin Invest
, vol.117
, pp. 2877-2888
-
-
Nomiyama, T.1
Perez-Tilve, D.2
Ogawa, D.3
Gizard, F.4
Zhao, Y.5
Heywood, E.B.6
Jones, K.L.7
Kawamori, R.8
Cassis, L.A.9
Tschöp, M.H.10
-
56
-
-
33745686086
-
Activation of hypoxia-inducible factor 1 during macrophage differentiation
-
Oda T, Hirota K, Nishi K, Takabuchi S, Oda S, Yamada H, Arai T, Fukuda K, Kita T, Adachi T, et al. 2006. Activation of hypoxia-inducible factor 1 during macrophage differentiation. Am J Physiol Cell Physiol 291:C104-13.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
-
-
Oda, T.1
Hirota, K.2
Nishi, K.3
Takabuchi, S.4
Oda, S.5
Yamada, H.6
Arai, T.7
Fukuda, K.8
Kita, T.9
Adachi, T.10
-
57
-
-
0033613545
-
Novel modulator for endothelial adhesion molecules - Adipocyte-derived plasma protein adiponectin
-
Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, Hotta K, Nishida M, Takahashi M, Nakamura T, et al. 1999. Novel modulator for endothelial adhesion molecules - Adipocyte-derived plasma protein adiponectin. Circulation 100:2473-76.
-
(1999)
Circulation
, vol.100
, pp. 2473-2476
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
Maeda, K.4
Kuriyama, H.5
Okamoto, Y.6
Hotta, K.7
Nishida, M.8
Takahashi, M.9
Nakamura, T.10
-
58
-
-
0034641647
-
Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-KB signaling through a cAMP-dependent pathway
-
Ouchi N, Kihara S, Arita Y, Okamoto Y, Maeda K, Kuriyama H, Hotta K, Nishida M, Takahashi M, Muraguchi M, et al. 2000. Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-KB signaling through a cAMP-dependent pathway. Circulation 102:1296-301.
-
(2000)
Circulation
, vol.102
, pp. 1296-1301
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
Okamoto, Y.4
Maeda, K.5
Kuriyama, H.6
Hotta, K.7
Nishida, M.8
Takahashi, M.9
Muraguchi, M.10
-
59
-
-
0037432152
-
Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue
-
Ouchi N, Kihara S, Funahashi T, Nakamura T, Nishida M, Kumada M, Okamoto Y, Ohashi K, Nagaretani H, Kishida K, et al. 2003. Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue. Circulation 107:67167-74.
-
(2003)
Circulation
, vol.107
, pp. 67167-67174
-
-
Ouchi, N.1
Kihara, S.2
Funahashi, T.3
Nakamura, T.4
Nishida, M.5
Kumada, M.6
Okamoto, Y.7
Ohashi, K.8
Nagaretani, H.9
Kishida, K.10
-
60
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, Tuncman G, Gorgun C, Glimcher LH, Hotamisligil GS. 2004. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306:457-61.
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
61
-
-
33750319951
-
12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes
-
12-PGJ2) prostaglandins stimulate IL-6 and MCP-1, but inhibit leptin, expression and secretion by 3T3-L1 adipocytes. Pflügers Archiv Eur J Physiol 453:177-87.
-
(2006)
Pflügers Archiv Eur J Physiol
, vol.453
, pp. 177-187
-
-
Peeraully, M.R.1
Sievert, H.2
Bulló, M.3
Wang, B.4
Trayhurn, P.5
-
62
-
-
0142062048
-
Intermittent hypoxia increases insulin resistance in genetically obese mice
-
Polotsky VY, Li J, Punjabi NM, Rubin AE, Smith PL, Schwartz AR, O'Donnell CP. 2003. Intermittent hypoxia increases insulin resistance in genetically obese mice. J Physiol 552:253-64.
-
(2003)
J Physiol
, vol.552
, pp. 253-264
-
-
Polotsky, V.Y.1
Li, J.2
Punjabi, N.M.3
Rubin, A.E.4
Smith, P.L.5
Schwartz, A.R.6
O'Donnell, C.P.7
-
63
-
-
0030779809
-
Tumor necrosis factor-α induces apoptosis of human adipose cells
-
Prins JB, Niesler CU, Winterford CM, Bright NA, Siddle K, O'Rahilly S, Walker NI, Cameron DP. 1997. Tumor necrosis factor-α induces apoptosis of human adipose cells. Diabetes 46:1939-44.
-
(1997)
Diabetes
, vol.46
, pp. 1939-1944
-
-
Prins, J.B.1
Niesler, C.U.2
Winterford, C.M.3
Bright, N.A.4
Siddle, K.5
O'Rahilly, S.6
Walker, N.I.7
Cameron, D.P.8
-
64
-
-
4544347749
-
Sleep-disordered breathing, glucose intolerance, and insulin resistance: The Sleep Heart Health Study
-
Punjabi NM, Shahar E, Redline S, Gottlieb DJ, Givelber R, Resnick HE. 2004. Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study. Am J Epidemiol 160:521-30.
-
(2004)
Am J Epidemiol
, vol.160
, pp. 521-530
-
-
Punjabi, N.M.1
Shahar, E.2
Redline, S.3
Gottlieb, D.J.4
Givelber, R.5
Resnick, H.E.6
-
65
-
-
0042330251
-
The adipocyte - at the crossroads of energy homeostasis, inflammation, and atherosclerosis
-
Rajala MW, Scherer PE. 2003. The adipocyte - at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 144:3765-73.
-
(2003)
Endocrinology
, vol.144
, pp. 3765-3773
-
-
Rajala, M.W.1
Scherer, P.E.2
-
66
-
-
38149142633
-
Obesity in C57BL/6J mice is characterised by adipose tissue hypoxia and cytotoxic T-cell infiltration
-
Rausch ME, Weisberg SP, Vardhana P, Tortorielllo DV. 2008. Obesity in C57BL/6J mice is characterised by adipose tissue hypoxia and cytotoxic T-cell infiltration. Int J Obesity 32:451-63.
-
(2008)
Int J Obesity
, vol.32
, pp. 451-463
-
-
Rausch, M.E.1
Weisberg, S.P.2
Vardhana, P.3
Tortorielllo, D.V.4
-
67
-
-
34547153223
-
Gene regulation under low oxygen: Holding your breath for transcription
-
Rocha S. 2007. Gene regulation under low oxygen: holding your breath for transcription. Trends Biochem Sci 32:389-97.
-
(2007)
Trends Biochem Sci
, vol.32
, pp. 389-397
-
-
Rocha, S.1
-
68
-
-
33845864967
-
Adipocytes as regulators of energy balance and glucose homeostasis
-
Rosen ED, Spiegelman BM. 2006. Adipocytes as regulators of energy balance and glucose homeostasis. Nature 444:847-53.
-
(2006)
Nature
, vol.444
, pp. 847-853
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
69
-
-
27444448072
-
Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome
-
Ryan S, Taylor CT, McNicholas WT. 2005. Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation 112:2660-67.
-
(2005)
Circulation
, vol.112
, pp. 2660-2667
-
-
Ryan, S.1
Taylor, C.T.2
McNicholas, W.T.3
-
70
-
-
33847267684
-
A critical role for p38 MAP kinase in NF-KB signaling during intermittent hypoxia/reoxygenation
-
Ryan S, McNicholas WT, Taylor CT. 2007. A critical role for p38 MAP kinase in NF-KB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun 355:728-33.
-
(2007)
Biochem Biophys Res Commun
, vol.355
, pp. 728-733
-
-
Ryan, S.1
McNicholas, W.T.2
Taylor, C.T.3
-
71
-
-
1942424955
-
Targets for TNF-α-induced lipolysis in human adipocytes
-
Ryden M, Arvidsson E, Blomqvist L, Perbeck L, Dicker A, Arner P. 2004. Targets for TNF-α-induced lipolysis in human adipocytes. Biochem Biophys Res Commun 318:168-75.
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 168-175
-
-
Ryden, M.1
Arvidsson, E.2
Blomqvist, L.3
Perbeck, L.4
Dicker, A.5
Arner, P.6
-
72
-
-
34250315764
-
Leptininduced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to cyclin D1 promoter via activation of STAT3
-
Saxena NK, Vertino PM, Anania FA, Sharma D. 2007. Leptininduced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to cyclin D1 promoter via activation of STAT3. J Biol Chem 282:13316-25.
-
(2007)
J Biol Chem
, vol.282
, pp. 13316-13325
-
-
Saxena, N.K.1
Vertino, P.M.2
Anania, F.A.3
Sharma, D.4
-
73
-
-
33748596091
-
Visfatin in adipocytes is upregulated by hypoxia through HIF1α-dependent mechanism
-
Segawa K, Fukuhara A, Hosogai N, Morita K, Okuno Y, Tanaka M, Nakagawa Y, Kihara S, Funahashi T, Komuro R. 2006. Visfatin in adipocytes is upregulated by hypoxia through HIF1α-dependent mechanism. Biochem Biophys Res Commun 349:875-82.
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 875-882
-
-
Segawa, K.1
Fukuhara, A.2
Hosogai, N.3
Morita, K.4
Okuno, Y.5
Tanaka, M.6
Nakagawa, Y.7
Kihara, S.8
Funahashi, T.9
Komuro, R.10
-
75
-
-
33645888426
-
Monocyte chemotactic protein-1 is a potential player in the negative crosstalk between adipose tissue and skeletal muscle
-
Sell H, Dietze-Schroeder D, Kaiser U, Eckel J. 2006b. Monocyte chemotactic protein-1 is a potential player in the negative crosstalk between adipose tissue and skeletal muscle. Endocrinology 147:2458-67.
-
(2006)
Endocrinology
, vol.147
, pp. 2458-2467
-
-
Sell, H.1
Dietze-Schroeder, D.2
Kaiser, U.3
Eckel, J.4
-
76
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
Semenza GL. 2001. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 13:167-71.
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 167-171
-
-
Semenza, G.L.1
-
77
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. 2003. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3:721-32.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
78
-
-
27644465299
-
Cytokine-mediated modulation of leptin and adiponectin secretion during in vitro adipogenesis: Evidence that tumor necrosis factor-α- and interleukin-1β-treated human preadipocytes are potent leptin producers
-
Simons PJ, van den Pangaart PS, van Roomen CP, Aerts JM, Boon L. 2005. Cytokine-mediated modulation of leptin and adiponectin secretion during in vitro adipogenesis: Evidence that tumor necrosis factor-α- and interleukin-1β-treated human preadipocytes are potent leptin producers. Cytokine 32:94-103.
-
(2005)
Cytokine
, vol.32
, pp. 94-103
-
-
Simons, P.J.1
van den Pangaart, P.S.2
van Roomen, C.P.3
Aerts, J.M.4
Boon, L.5
-
80
-
-
0038066517
-
Expression of metallothionein-III induced by hypoxia attenuates hypoxia-induced cell death in vitro
-
Tanji K, Irie Y, Uchida Y, Mori F, Satoh K, Mizushima Y, Wakabayashi K. 2003. Expression of metallothionein-III induced by hypoxia attenuates hypoxia-induced cell death in vitro. Brain Res 976:125-29.
-
(2003)
Brain Res
, vol.976
, pp. 125-129
-
-
Tanji, K.1
Irie, Y.2
Uchida, Y.3
Mori, F.4
Satoh, K.5
Mizushima, Y.6
Wakabayashi, K.7
-
81
-
-
22844437863
-
Endocrine and signalling role of adipose tissue: New perspectives on fat
-
Trayhurn P. 2005a. Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiol Scand 184:285-93.
-
(2005)
Acta Physiol Scand
, vol.184
, pp. 285-293
-
-
Trayhurn, P.1
-
82
-
-
18844409597
-
The biology of obesity
-
Trayhurn P. 2005b. The biology of obesity. Proc Nutr Soc 64:31-38.
-
(2005)
Proc Nutr Soc
, vol.64
, pp. 31-38
-
-
Trayhurn, P.1
-
83
-
-
0034890103
-
Physiological role of adipose tissue: White adipose tissue as an endocrine and secretory organ
-
Trayhurn P, Beattie JH. 2001. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc 60:329-39.
-
(2001)
Proc Nutr Soc
, vol.60
, pp. 329-339
-
-
Trayhurn, P.1
Beattie, J.H.2
-
84
-
-
6944237757
-
Adipokines: Inflammation and the pleiotropic role of white adipose tissue
-
Trayhurn P, Wood IS. 2004. Adipokines: Inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 92:347-55.
-
(2004)
Br J Nutr
, vol.92
, pp. 347-355
-
-
Trayhurn, P.1
Wood, I.S.2
-
85
-
-
27844545767
-
Signalling role of adipose tissue: Adipokines and inflammation in obesity
-
Trayhurn P, Wood IS. 2005. Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem Soc Trans 33:1078-81.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 1078-1081
-
-
Trayhurn, P.1
Wood, I.S.2
-
86
-
-
47849121225
-
Hypoxia in adipose tissue: A basis for the dysregulation of tissue function in obesity?
-
Trayhurn P, Wang B, Wood IS. 2008. Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br J Nutr 100:227-35.
-
(2008)
Br J Nutr
, vol.100
, pp. 227-235
-
-
Trayhurn, P.1
Wang, B.2
Wood, I.S.3
-
88
-
-
18544368076
-
Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans
-
Virtanen KA, Lonnroth P, Parkkola R, Peltoniemi P, Asola M, Viljanen T, Tolvanen T, Knuuti J, Ronnemaa T, Huupponen R, et al. 2002. Glucose uptake and perfusion in subcutaneous and visceral adipose tissue during insulin stimulation in nonobese and obese humans. J Clin Endocrinol Metab 87:3902-10.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3902-3910
-
-
Virtanen, K.A.1
Lonnroth, P.2
Parkkola, R.3
Peltoniemi, P.4
Asola, M.5
Viljanen, T.6
Tolvanen, T.7
Knuuti, J.8
Ronnemaa, T.9
Huupponen, R.10
-
89
-
-
15444367036
-
Expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture: Integrated response to TNF-α
-
Wang B, Jenkins JR, Trayhurn P. 2005. Expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture: Integrated response to TNF-α. Am J Physiol Endocrinol Metab 288:E731-40.
-
(2005)
Am J Physiol Endocrinol Metab
, vol.288
-
-
Wang, B.1
Jenkins, J.R.2
Trayhurn, P.3
-
90
-
-
33745511212
-
Acute and prolonged effects of TNF-α on the expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture
-
Wang B, Trayhurn P. 2006. Acute and prolonged effects of TNF-α on the expression and secretion of inflammation-related adipokines by human adipocytes differentiated in culture. Pflügers Archiv Eur J Physiol 452:418-27.
-
(2006)
Pflügers Archiv Eur J Physiol
, vol.452
, pp. 418-427
-
-
Wang, B.1
Trayhurn, P.2
-
91
-
-
35448934913
-
Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes
-
Wang B, Wood IS, Trayhurn P. 2007. Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes. Pflügers Archiv Eur J Physiol 455:479-92.
-
(2007)
Pflügers Archiv Eur J Physiol
, vol.455
, pp. 479-492
-
-
Wang, B.1
Wood, I.S.2
Trayhurn, P.3
-
92
-
-
39149112487
-
PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes
-
Wang B, Wood IS, Trayhurn P. 2008. PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes. Biochem Biophys Res Commun 368:88-93.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 88-93
-
-
Wang, B.1
Wood, I.S.2
Trayhurn, P.3
-
93
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW, Jr. 2003. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112:1796-808.
-
(2003)
J Clin Invest
, vol.112
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
95
-
-
34248595689
-
Obstructive sleep apnea, cardiovascular disease, and inflammation - is NF-KB the key?
-
Williams A, Scharf SM. 2007. Obstructive sleep apnea, cardiovascular disease, and inflammation - is NF-KB the key? Sleep Breathing 11:69-76.
-
(2007)
Sleep Breathing
, vol.11
, pp. 69-76
-
-
Williams, A.1
Scharf, S.M.2
-
96
-
-
34547583651
-
Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-D-glucose uptake in human adipocytes
-
Wood IS, Wang B, Lorente-Cebriaαn S, Trayhurn P. 2007. Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-D-glucose uptake in human adipocytes. Biochem Biophys Res Commun 361:468-73.
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 468-473
-
-
Wood, I.S.1
Wang, B.2
Lorente-Cebriaαn, S.3
Trayhurn, P.4
-
97
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, et al. 2003. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest 112:1821-30.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
-
98
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, et al. 2001. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7:941-46.
-
(2001)
Nat Med
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hara, K.6
Mori, Y.7
Ide, T.8
Murakami, K.9
Tsuboyama-Kasaoka, N.10
-
99
-
-
35148854599
-
Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice
-
Ye J, Gao Z, Yin J, He Q. 2007. Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. Am J Physiol Endocrinol Metab 293:E1118-28.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
-
-
Ye, J.1
Gao, Z.2
Yin, J.3
He, Q.4
-
100
-
-
14244256421
-
Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia
-
Yuan G, Nanduri J, Bhasker CR, Semenza GL, Prabhakar NR. 2005. Ca2+/calmodulin kinase-dependent activation of hypoxia inducible factor 1 transcriptional activity in cells subjected to intermittent hypoxia. J Biol Chem 280:4321-28.
-
(2005)
J Biol Chem
, vol.280
, pp. 4321-4328
-
-
Yuan, G.1
Nanduri, J.2
Bhasker, C.R.3
Semenza, G.L.4
Prabhakar, N.R.5
-
101
-
-
0346250163
-
Adipose tissue, insulin action and vascular disease: Inflammatory signals
-
Yudkin JS. 2003. Adipose tissue, insulin action and vascular disease: inflammatory signals. Int J Obesity 27 Suppl 3:S25-28.
-
(2003)
Int J Obesity
, vol.27
, Issue.SUPPL. 3
-
-
Yudkin, J.S.1
-
102
-
-
0036198010
-
Inhibition of PPARγ2 gene expression by the HIF-1-regulated gene DEC1/ Stra13: A mechanism for regulation of adipogenesis by hypoxia
-
Yun Z, Maecker HL, Johnson RS, Giaccia AJ. 2002. Inhibition of PPARγ2 gene expression by the HIF-1-regulated gene DEC1/ Stra13: a mechanism for regulation of adipogenesis by hypoxia. Dev Cell 2:331-41.
-
(2002)
Dev Cell
, vol.2
, pp. 331-341
-
-
Yun, Z.1
Maecker, H.L.2
Johnson, R.S.3
Giaccia, A.J.4
-
103
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homolog
-
Zhang YY, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. 1994. Positional cloning of the mouse obese gene and its human homolog. Nature 372:425-32.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
104
-
-
34548124842
-
Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes
-
Zhou L, Sell H, Eckardt K, Yang Z, Eckel J. 2007. Conditioned medium obtained from in vitro differentiated adipocytes and resistin induce insulin resistance in human hepatocytes. FEBS Lett 581:4303-08.
-
(2007)
FEBS Lett
, vol.581
, pp. 4303-4308
-
-
Zhou, L.1
Sell, H.2
Eckardt, K.3
Yang, Z.4
Eckel, J.5
-
105
-
-
20744449945
-
Hypoxia Inhibition of Adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-β/ Smad3 signaling
-
Zhou S, Lechpammer S, Greenberger JS, Glowacki J. 2005. Hypoxia Inhibition of Adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-β/ Smad3 signaling. J Biol Chem 280:22688-96.
-
(2005)
J Biol Chem
, vol.280
, pp. 22688-22696
-
-
Zhou, S.1
Lechpammer, S.2
Greenberger, J.S.3
Glowacki, J.4
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