메뉴 건너뛰기




Volumn 63, Issue 2, 2017, Pages 103-117

Genome and Epigenome Editing in Mechanistic Studies of Human Aging and Aging-Related Disease

Author keywords

Aging; Aging related disease; CRISPR; Epigenetics; Epigenome editing; Genetics; Genome editing

Indexed keywords

AGING; AGING RELATED DISEASE; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; EPIGENETICS; GENE EDITING; GENETIC ENGINEERING; GENOME; GERIATRIC DISORDER; HUMAN; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; ANIMAL; CRISPR CAS SYSTEM; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; TRANSLATIONAL RESEARCH; TRENDS;

EID: 85006325497     PISSN: 0304324X     EISSN: 14230003     Source Type: Journal    
DOI: 10.1159/000452972     Document Type: Review
Times cited : (13)

References (60)
  • 1
    • 84879264708 scopus 로고    scopus 로고
    • ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
    • Gaj T, Gersbach CA, Barbas CF 3rd: ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol 2013; 31: 397-405.
    • (2013) Trends Biotechnol , vol.31 , pp. 397-405
    • Gaj, T.1    Gersbach, C.A.2    Barbas, C.F.3
  • 9
    • 84942793975 scopus 로고    scopus 로고
    • Photoactivatable CRISPR-Cas9 for optogenetic genome editing
    • Nihongaki Y, Kawano F, Nakajima T, Sato M: Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol 2015; 33: 755-760.
    • (2015) Nat Biotechnol , vol.33 , pp. 755-760
    • Nihongaki, Y.1    Kawano, F.2    Nakajima, T.3    Sato, M.4
  • 10
    • 84923226022 scopus 로고    scopus 로고
    • Synthesizing and gate genetic circuits based on CRISPR-Cas9 for identification of bladder cancer cells
    • Liu Y, Zeng Y, Liu L, Zhuang C, Fu X, Huang W, Cai Z: Synthesizing and gate genetic circuits based on CRISPR-Cas9 for identification of bladder cancer cells. Nat Commun 2014; 5: 5393.
    • (2014) Nat Commun , vol.5 , pp. 5393
    • Liu, Y.1    Zeng, Y.2    Liu, L.3    Zhuang, C.4    Fu, X.5    Huang, W.6    Cai, Z.7
  • 19
    • 84896929630 scopus 로고    scopus 로고
    • Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
    • Fu Y, Sander JD, Reyon D, Cascio VM, Joung JK: Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nat Biotechnol 2014; 32: 279-284.
    • (2014) Nat Biotechnol , vol.32 , pp. 279-284
    • Fu, Y.1    Sander, J.D.2    Reyon, D.3    Cascio, V.M.4    Joung, J.K.5
  • 20
    • 84960911917 scopus 로고    scopus 로고
    • Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
    • Richardson CD, Ray GJ, DeWitt MA, Curie GL, Corn JE: Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA. Nat Biotechnol 2016; 34: 339-344.
    • (2016) Nat Biotechnol , vol.34 , pp. 339-344
    • Richardson, C.D.1    Ray, G.J.2    DeWitt, M.A.3    Curie, G.L.4    Corn, J.E.5
  • 21
    • 84961334208 scopus 로고    scopus 로고
    • RS-1 enhances CRISPR/Cas9-and TALENmediated knock-in efficiency
    • Song J, Yang D, Xu J, Zhu T, Chen YE, Zhang J: RS-1 enhances CRISPR/Cas9-and TALENmediated knock-in efficiency. Nat Commun 2016; 7: 10548.
    • (2016) Nat Commun , vol.7 , pp. 10548
    • Song, J.1    Yang, D.2    Xu, J.3    Zhu, T.4    Chen, Y.E.5    Zhang, J.6
  • 22
    • 84929166074 scopus 로고    scopus 로고
    • Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
    • Maruyama T, Dougan SK, Truttmann MC, Bilate AM, Ingram JR, Ploegh HL: Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining. Nat Biotechnol 2015; 33: 538-542.
    • (2015) Nat Biotechnol , vol.33 , pp. 538-542
    • Maruyama, T.1    Dougan, S.K.2    Truttmann, M.C.3    Bilate, A.M.4    Ingram, J.R.5    Ploegh, H.L.6
  • 24
    • 84969963103 scopus 로고    scopus 로고
    • Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair
    • He X, Tan C, Wang F, Wang Y, Zhou R, Cui D, You W, Zhao H, Ren J, Feng B: Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair. Nucleic Acids Res 2016; 44:e85.
    • (2016) Nucleic Acids Res , vol.44 , pp. e85
    • He, X.1    Tan, C.2    Wang, F.3    Wang, Y.4    Zhou, R.5    Cui, D.6    You, W.7    Zhao, H.8    Ren, J.9    Feng, B.10
  • 25
    • 84971006562 scopus 로고    scopus 로고
    • Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
    • Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR: Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature 2016; 533: 420-424.
    • (2016) Nature , vol.533 , pp. 420-424
    • Komor, A.C.1    Kim, Y.B.2    Packer, M.S.3    Zuris, J.A.4    Liu, D.R.5
  • 26
    • 84923362619 scopus 로고    scopus 로고
    • Integrative analysis of 111 reference human epigenomes
    • Roadmap Epigenomics Consortium
    • Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, et al: Integrative analysis of 111 reference human epigenomes. Nature 2015; 518: 317-330.
    • (2015) Nature , vol.518 , pp. 317-330
    • Kundaje, A.1    Meuleman, W.2    Ernst, J.3    Bilenky, M.4    Yen, A.5    Heravi-Moussavi, A.6
  • 32
    • 84966692476 scopus 로고    scopus 로고
    • High-throughput, high-resolution mapping of protein localization in mammalian brain by in vivo genome editing
    • Mikuni T, Nishiyama J, Sun Y, Kamasawa N, Yasuda R: High-throughput, high-resolution mapping of protein localization in mammalian brain by in vivo genome editing. Cell 2016; 165: 1803-1817.
    • (2016) Cell , vol.165 , pp. 1803-1817
    • Mikuni, T.1    Nishiyama, J.2    Sun, Y.3    Kamasawa, N.4    Yasuda, R.5
  • 33
    • 84981714781 scopus 로고    scopus 로고
    • Live cell imaging reveals the dynamics of telomerase recruitment to telomeres
    • e9
    • Schmidt JC, Zaug AJ, Cech TR: Live cell imaging reveals the dynamics of telomerase recruitment to telomeres. Cell 2016; 166: 1188-1197.e9.
    • (2016) Cell , vol.166 , pp. 1188-1197
    • Schmidt, J.C.1    Zaug, A.J.2    Cech, T.R.3
  • 35
    • 84966908028 scopus 로고    scopus 로고
    • Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow
    • Ma H, Tu LC, Naseri A, Huisman M, Zhang S, Grunwald D, Pederson T: Multiplexed labeling of genomic loci with dCas9 and engineered sgRNAs using CRISPRainbow. Nat Biotechnol 2016; 34: 528-530.
    • (2016) Nat Biotechnol , vol.34 , pp. 528-530
    • Ma, H.1    Tu, L.C.2    Naseri, A.3    Huisman, M.4    Zhang, S.5    Grunwald, D.6    Pederson, T.7
  • 39
    • 84878738557 scopus 로고    scopus 로고
    • Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model
    • Liu B, Wang Z, Zhang L, Ghosh S, Zheng H, Zhou Z: Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model. Nat Commun 2013; 4: 1868.
    • (2013) Nat Commun , vol.4 , pp. 1868
    • Liu, B.1    Wang, Z.2    Zhang, L.3    Ghosh, S.4    Zheng, H.5    Zhou, Z.6
  • 43
    • 84981340960 scopus 로고    scopus 로고
    • Epigenetic mechanisms of longevity and aging
    • Sen P, Shah PP, Nativio R, Berger SL: Epigenetic mechanisms of longevity and aging. Cell 2016; 166: 822-839.
    • (2016) Cell , vol.166 , pp. 822-839
    • Sen, P.1    Shah, P.P.2    Nativio, R.3    Berger, S.L.4
  • 44
    • 84964255612 scopus 로고    scopus 로고
    • Monkeys genetically modified to show autism symptoms
    • Cyranoski D: Monkeys genetically modified to show autism symptoms. Nature 2016; 529: 449.
    • (2016) Nature , vol.529 , pp. 449
    • Cyranoski, D.1
  • 46
    • 84872007491 scopus 로고    scopus 로고
    • Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford progeria and Werner syndrome
    • Heyn H, Moran S, Esteller M: Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford progeria and Werner syndrome. Epigenetics 2013; 8: 28-33.
    • (2013) Epigenetics , vol.8 , pp. 28-33
    • Heyn, H.1    Moran, S.2    Esteller, M.3
  • 48
    • 84982136632 scopus 로고    scopus 로고
    • Chinese scientists to pioneer first human CRISPR trial
    • Cyranoski D: Chinese scientists to pioneer first human CRISPR trial. Nature 2016; 535: 476-477.
    • (2016) Nature , vol.535 , pp. 476-477
    • Cyranoski, D.1
  • 49
    • 85013159608 scopus 로고    scopus 로고
    • First-in-human CRISPR trial
    • First-in-human CRISPR trial. Nat Biotechnol 2016; 34: 796.
    • (2016) Nat Biotechnol , vol.34 , pp. 796
  • 59
    • 85013155314 scopus 로고    scopus 로고
    • A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells
    • Epub ahead of print
    • Chaikind B, Bessen JL, Thompson DB, Hu JH, Liu DR: A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells. Nucleic Acids Res 2016, Epub ahead of print.
    • (2016) Nucleic Acids Res
    • Chaikind, B.1    Bessen, J.L.2    Thompson, D.B.3    Hu, J.H.4    Liu, D.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.