Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres

Cell

Volumn 166, Issue 5, 2016, Pages 1188-1197.e9

  Schmidt, Jens C ^a   Zaug, Arthur J ^a   Cech, Thomas R ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

CRISPR Cas9; diffusion constant; dynamics; genome editing; Halo tag; live cell imaging; telomerase recruitment; telomeres; TERT; TPP1

Indexed keywords

REPETITIVE DNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; BACTERIAL PROTEIN; CAS9 ENDONUCLEASE STREPTOCOCCUS PYOGENES; ENDONUCLEASE; PTOP PROTEIN, HUMAN; TELOMERE BINDING PROTEIN; TERT PROTEIN, HUMAN;

ARTICLE; CELL CYCLE S PHASE; CELL MIGRATION; CHROMOSOME; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; COILED BODY; CONTROLLED STUDY; DIFFUSION; DNA SEQUENCE; FLUORESCENCE IMAGING; GENOME; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; TELOMERE; TELOMERE HOMEOSTASIS; WESTERN BLOTTING; CELL LINE; CELL NUCLEUS; CHEMISTRY; ENZYMOLOGY; GENE EDITING; GENETICS; HELA CELL LINE; HUMAN GENOME; METABOLISM; NUCLEOCYTOPLASMIC TRANSPORT; PROTEIN DOMAIN; SACCHAROMYCES CEREVISIAE; THREE DIMENSIONAL IMAGING;

ACTIVE TRANSPORT, CELL NUCLEUS; BACTERIAL PROTEINS; CELL LINE; CELL NUCLEUS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; COILED BODIES; ENDONUCLEASES; GENE EDITING; GENOME, HUMAN; HELA CELLS; HUMANS; IMAGING, THREE-DIMENSIONAL; PROTEIN DOMAINS; S PHASE; SACCHAROMYCES CEREVISIAE; TELOMERASE; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE-BINDING PROTEINS;

EID: 84981714781     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.07.033     Document Type: Article

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