-
1
-
-
84906329614
-
Newer targets for modulation of intraocular pressure: focus on adenosine receptor signaling pathways
-
Agarwal, R., Agarwal, P., Newer targets for modulation of intraocular pressure: focus on adenosine receptor signaling pathways. Expert Opin. Ther. Targets 18 (2014), 527–539.
-
(2014)
Expert Opin. Ther. Targets
, vol.18
, pp. 527-539
-
-
Agarwal, R.1
Agarwal, P.2
-
2
-
-
0031856621
-
Prostaglandin derivates as ocular hypotensive agents
-
Alm, A., Prostaglandin derivates as ocular hypotensive agents. Prog. Retin Eye Res. 17 (1998), 291–312.
-
(1998)
Prog. Retin Eye Res.
, vol.17
, pp. 291-312
-
-
Alm, A.1
-
3
-
-
0019818602
-
Age-related changes in trabecular meshwork cellularity
-
Alvarado, J., Murphy, C., Polansky, J., Juster, R., Age-related changes in trabecular meshwork cellularity. Investigative Ophthalmol. Vis. Sci. 21 (1981), 714–727.
-
(1981)
Investigative Ophthalmol. Vis. Sci.
, vol.21
, pp. 714-727
-
-
Alvarado, J.1
Murphy, C.2
Polansky, J.3
Juster, R.4
-
4
-
-
84887321623
-
Rho-kinase: regulation, (dys)function, and inhibition
-
Amin, E., Dubey, B.N., Zhang, S.C., Gremer, L., Dvorsky, R., Moll, J.M., Taha, M.S., Nagel-Steger, L., Piekorz, R.P., Somlyo, A.V., Ahmadian, M.R., Rho-kinase: regulation, (dys)function, and inhibition. Biol. Chem. 394 (2013), 1399–1410.
-
(2013)
Biol. Chem.
, vol.394
, pp. 1399-1410
-
-
Amin, E.1
Dubey, B.N.2
Zhang, S.C.3
Gremer, L.4
Dvorsky, R.5
Moll, J.M.6
Taha, M.S.7
Nagel-Steger, L.8
Piekorz, R.P.9
Somlyo, A.V.10
Ahmadian, M.R.11
-
5
-
-
84921539331
-
Double-masked, randomized, dose-response study of AR-13324 versus latanoprost in patients with elevated intraocular pressure
-
Bacharach, J., Dubiner, H.B., Levy, B., Kopczynski, C.C., Novack, G.D., Group, A.-C.S., Double-masked, randomized, dose-response study of AR-13324 versus latanoprost in patients with elevated intraocular pressure. Ophthalmology 122 (2015), 302–307.
-
(2015)
Ophthalmology
, vol.122
, pp. 302-307
-
-
Bacharach, J.1
Dubiner, H.B.2
Levy, B.3
Kopczynski, C.C.4
Novack, G.D.5
Group, A.-C.S.6
-
6
-
-
70350752183
-
Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells
-
Bermel, C., Tonges, L., Planchamp, V., Gillardon, F., Weishaupt, J.H., Dietz, G.P., Bahr, M., Lingor, P., Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells. Mol. Cell Neurosci. 42 (2009), 427–437.
-
(2009)
Mol. Cell Neurosci.
, vol.42
, pp. 427-437
-
-
Bermel, C.1
Tonges, L.2
Planchamp, V.3
Gillardon, F.4
Weishaupt, J.H.5
Dietz, G.P.6
Bahr, M.7
Lingor, P.8
-
7
-
-
33751178359
-
Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists
-
Bertrand, J., Di Polo, A., McKerracher, L., Enhanced survival and regeneration of axotomized retinal neurons by repeated delivery of cell-permeable C3-like Rho antagonists. Neurobiol. Dis. 25 (2007), 65–72.
-
(2007)
Neurobiol. Dis.
, vol.25
, pp. 65-72
-
-
Bertrand, J.1
Di Polo, A.2
McKerracher, L.3
-
8
-
-
13944274451
-
Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats
-
Bertrand, J., Winton, M.J., Rodriguez-Hernandez, N., Campenot, R.B., McKerracher, L., Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats. J. Neurosci. 25 (2005), 1113–1121.
-
(2005)
J. Neurosci.
, vol.25
, pp. 1113-1121
-
-
Bertrand, J.1
Winton, M.J.2
Rodriguez-Hernandez, N.3
Campenot, R.B.4
McKerracher, L.5
-
9
-
-
84856210692
-
The development of a rat in vitro model of spinal cord injury demonstrating the additive effects of Rho and ROCK inhibitors on neurite outgrowth and myelination
-
Boomkamp, S.D., Riehle, M.O., Wood, J., Olson, M.F., Barnett, S.C., The development of a rat in vitro model of spinal cord injury demonstrating the additive effects of Rho and ROCK inhibitors on neurite outgrowth and myelination. Glia 60 (2012), 441–456.
-
(2012)
Glia
, vol.60
, pp. 441-456
-
-
Boomkamp, S.D.1
Riehle, M.O.2
Wood, J.3
Olson, M.F.4
Barnett, S.C.5
-
10
-
-
84922938368
-
Prevention of nocturnal elevation of intraocular pressure by gene transfer of dominant-negative RhoA in rats
-
Borras, T., Buie, L.K., Spiga, M.G., Carabana, J., Prevention of nocturnal elevation of intraocular pressure by gene transfer of dominant-negative RhoA in rats. JAMA Ophthalmol. 133 (2015), 182–190.
-
(2015)
JAMA Ophthalmol.
, vol.133
, pp. 182-190
-
-
Borras, T.1
Buie, L.K.2
Spiga, M.G.3
Carabana, J.4
-
11
-
-
0842281652
-
Rho and Rac take center stage
-
Burridge, K., Wennerberg, K., Rho and Rac take center stage. Cell 116 (2004), 167–179.
-
(2004)
Cell
, vol.116
, pp. 167-179
-
-
Burridge, K.1
Wennerberg, K.2
-
12
-
-
84939825415
-
Regulation of endothelin-1-induced trabecular meshwork cell contractility by latanoprostene bunod
-
Cavet, M.E., Vollmer, T.R., Harrington, K.L., VanDerMeid, K., Richardson, M.E., Regulation of endothelin-1-induced trabecular meshwork cell contractility by latanoprostene bunod. Investigative Ophthalmol. Vis. Sci. 56 (2015), 4108–4116.
-
(2015)
Investigative Ophthalmol. Vis. Sci.
, vol.56
, pp. 4108-4116
-
-
Cavet, M.E.1
Vollmer, T.R.2
Harrington, K.L.3
VanDerMeid, K.4
Richardson, M.E.5
-
13
-
-
18644378279
-
Effects of endothelin-1 on human trabecular meshwork cell contraction. an in vitro cell culture model
-
Cellini, M., Versura, P., Trere, D., Campos, E.C., Effects of endothelin-1 on human trabecular meshwork cell contraction. an in vitro cell culture model. Ophthalmic Res. 37 (2005), 43–49.
-
(2005)
Ophthalmic Res.
, vol.37
, pp. 43-49
-
-
Cellini, M.1
Versura, P.2
Trere, D.3
Campos, E.C.4
-
14
-
-
84874433733
-
Regulation of small GTPases by GEFs, GAPs, and GDIs
-
Cherfils, J., Zeghouf, M., Regulation of small GTPases by GEFs, GAPs, and GDIs. Physiol. Rev. 93 (2013), 269–309.
-
(2013)
Physiol. Rev.
, vol.93
, pp. 269-309
-
-
Cherfils, J.1
Zeghouf, M.2
-
15
-
-
84872051373
-
Correlation of endothelin-1 concentration in aqueous humor with intraocular pressure in primary open angle and pseudoexfoliation glaucoma
-
Choritz, L., Machert, M., Thieme, H., Correlation of endothelin-1 concentration in aqueous humor with intraocular pressure in primary open angle and pseudoexfoliation glaucoma. Investigative Ophthalmol. Vis. Sci. 53 (2012), 7336–7342.
-
(2012)
Investigative Ophthalmol. Vis. Sci.
, vol.53
, pp. 7336-7342
-
-
Choritz, L.1
Machert, M.2
Thieme, H.3
-
16
-
-
33747195035
-
Recent evidence for an involvement of rho-kinase in cerebral vascular disease
-
Chrissobolis, S., Sobey, C.G., Recent evidence for an involvement of rho-kinase in cerebral vascular disease. Stroke 37 (2006), 2174–2180.
-
(2006)
Stroke
, vol.37
, pp. 2174-2180
-
-
Chrissobolis, S.1
Sobey, C.G.2
-
17
-
-
0029995797
-
Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
-
Chrzanowska-Wodnicka, M., Burridge, K., Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 133 (1996), 1403–1415.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 1403-1415
-
-
Chrzanowska-Wodnicka, M.1
Burridge, K.2
-
18
-
-
64249159576
-
The role of steroids in outflow resistance
-
Clark, A.F., Wordinger, R.J., The role of steroids in outflow resistance. Exp. eye Res. 88 (2009), 752–759.
-
(2009)
Exp. eye Res.
, vol.88
, pp. 752-759
-
-
Clark, A.F.1
Wordinger, R.J.2
-
19
-
-
0026518715
-
Localization of smooth muscle and nonmuscle actin isoforms in the human aqueous outflow pathway
-
de Kater, A.W., Shahsafaei, A., Epstein, D.L., Localization of smooth muscle and nonmuscle actin isoforms in the human aqueous outflow pathway. Investigative Ophthalmol. Vis. Sci. 33 (1992), 424–429.
-
(1992)
Investigative Ophthalmol. Vis. Sci.
, vol.33
, pp. 424-429
-
-
de Kater, A.W.1
Shahsafaei, A.2
Epstein, D.L.3
-
20
-
-
84883245283
-
Rho GTPases in neurodegeneration diseases
-
DeGeer, J., Lamarche-Vane, N., Rho GTPases in neurodegeneration diseases. Exp. Cell Res. 319 (2013), 2384–2394.
-
(2013)
Exp. Cell Res.
, vol.319
, pp. 2384-2394
-
-
DeGeer, J.1
Lamarche-Vane, N.2
-
21
-
-
84960350375
-
Investigation of the rho-kinase gene polymorphism in primary open-angle glaucoma
-
Demiryurek, S., Okumus, S., Bozgeyik, I., Oztuzcu, S., Coskun, E., Mat, E., Durucu, E., Tatar, M.G., Erbagci, I., Gurler, B., Demiryurek, A.T., Investigation of the rho-kinase gene polymorphism in primary open-angle glaucoma. Ophthalmic Genet. 37 (2016), 9–13.
-
(2016)
Ophthalmic Genet.
, vol.37
, pp. 9-13
-
-
Demiryurek, S.1
Okumus, S.2
Bozgeyik, I.3
Oztuzcu, S.4
Coskun, E.5
Mat, E.6
Durucu, E.7
Tatar, M.G.8
Erbagci, I.9
Gurler, B.10
Demiryurek, A.T.11
-
22
-
-
84866043681
-
Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of Rho signaling
-
Diskin, S., Chen, W.S., Cao, Z., Gyawali, S., Gong, H., Soza, A., Gonzalez, A., Panjwani, N., Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of Rho signaling. PloS one, 7, 2012, e44400.
-
(2012)
PloS one
, vol.7
, pp. e44400
-
-
Diskin, S.1
Chen, W.S.2
Cao, Z.3
Gyawali, S.4
Gong, H.5
Soza, A.6
Gonzalez, A.7
Panjwani, N.8
-
23
-
-
84958214730
-
Discovery of molecular therapeutics for glaucoma: challenges, successes, and promising directions
-
Donegan, R.K., Lieberman, R.L., Discovery of molecular therapeutics for glaucoma: challenges, successes, and promising directions. J. Med. Chem. 59 (2016), 788–809.
-
(2016)
J. Med. Chem.
, vol.59
, pp. 788-809
-
-
Donegan, R.K.1
Lieberman, R.L.2
-
24
-
-
84902290147
-
Effects of intravitreal injection of a Rho-GTPase inhibitor (BA-210), or CNTF combined with an analogue of cAMP, on the dendritic morphology of regenerating retinal ganglion cells
-
Drummond, E.S., Rodger, J., Penrose, M., Robertson, D., Hu, Y., Harvey, A.R., Effects of intravitreal injection of a Rho-GTPase inhibitor (BA-210), or CNTF combined with an analogue of cAMP, on the dendritic morphology of regenerating retinal ganglion cells. Restor. Neurol. Neurosci. 32 (2014), 391–402.
-
(2014)
Restor. Neurol. Neurosci.
, vol.32
, pp. 391-402
-
-
Drummond, E.S.1
Rodger, J.2
Penrose, M.3
Robertson, D.4
Hu, Y.5
Harvey, A.R.6
-
25
-
-
0032938489
-
Acto-myosin drug effects and aqueous outflow function
-
Epstein, D.L., Rowlette, L.L., Roberts, B.C., Acto-myosin drug effects and aqueous outflow function. Investigative Ophthalmol. Vis. Sci. 40 (1999), 74–81.
-
(1999)
Investigative Ophthalmol. Vis. Sci.
, vol.40
, pp. 74-81
-
-
Epstein, D.L.1
Rowlette, L.L.2
Roberts, B.C.3
-
26
-
-
0026680251
-
Ethacrynic acid induces reversible shape and cytoskeletal changes in cultured cells
-
Erickson-Lamy, K., Schroeder, A., Epstein, D.L., Ethacrynic acid induces reversible shape and cytoskeletal changes in cultured cells. Investigative Ophthalmol. Vis. Sci. 33 (1992), 2631–2640.
-
(1992)
Investigative Ophthalmol. Vis. Sci.
, vol.33
, pp. 2631-2640
-
-
Erickson-Lamy, K.1
Schroeder, A.2
Epstein, D.L.3
-
27
-
-
0037069690
-
Rho GTPases in cell biology
-
Etienne-Manneville, S., Hall, A., Rho GTPases in cell biology. Nature 420 (2002), 629–635.
-
(2002)
Nature
, vol.420
, pp. 629-635
-
-
Etienne-Manneville, S.1
Hall, A.2
-
28
-
-
84896726589
-
Rho kinase inhibitors: a patent review (2012-2013)
-
Feng, Y., LoGrasso, P.V., Rho kinase inhibitors: a patent review (2012-2013). Expert Opin. Ther. Pat. 24 (2014), 295–307.
-
(2014)
Expert Opin. Ther. Pat.
, vol.24
, pp. 295-307
-
-
Feng, Y.1
LoGrasso, P.V.2
-
29
-
-
84962193209
-
Rho kinase (ROCK) inhibitors and their therapeutic potential
-
Feng, Y., LoGrasso, P.V., Defert, O., Li, R., Rho kinase (ROCK) inhibitors and their therapeutic potential. J. Med. Chem. 59 (2015), 2269–2300.
-
(2015)
J. Med. Chem.
, vol.59
, pp. 2269-2300
-
-
Feng, Y.1
LoGrasso, P.V.2
Defert, O.3
Li, R.4
-
30
-
-
84922239821
-
Rho-ROCK inhibition in the treatment of spinal cord injury
-
Forgione, N., Fehlings, M.G., Rho-ROCK inhibition in the treatment of spinal cord injury. World Neurosurg. 82 (2014), e535–539.
-
(2014)
World Neurosurg.
, vol.82
, pp. e535-539
-
-
Forgione, N.1
Fehlings, M.G.2
-
31
-
-
84871871136
-
Involvement of RhoA/Rho-associated kinase signal transduction pathway in dexamethasone-induced alterations in aqueous outflow
-
Fujimoto, T., Inoue, T., Kameda, T., Kasaoka, N., Inoue-Mochita, M., Tsuboi, N., Tanihara, H., Involvement of RhoA/Rho-associated kinase signal transduction pathway in dexamethasone-induced alterations in aqueous outflow. Investigative Ophthalmol. Vis. Sci. 53 (2012), 7097–7108.
-
(2012)
Investigative Ophthalmol. Vis. Sci.
, vol.53
, pp. 7097-7108
-
-
Fujimoto, T.1
Inoue, T.2
Kameda, T.3
Kasaoka, N.4
Inoue-Mochita, M.5
Tsuboi, N.6
Tanihara, H.7
-
32
-
-
84910092956
-
Axon growth inhibition by RhoA/ROCK in the central nervous system
-
Fujita, Y., Yamashita, T., Axon growth inhibition by RhoA/ROCK in the central nervous system. Front. Neurosci., 8, 2014, 338.
-
(2014)
Front. Neurosci.
, vol.8
, pp. 338
-
-
Fujita, Y.1
Yamashita, T.2
-
33
-
-
0035150402
-
Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
-
Fukata, Y., Amano, M., Kaibuchi, K., Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol. Sci. 22 (2001), 32–39.
-
(2001)
Trends Pharmacol. Sci.
, vol.22
, pp. 32-39
-
-
Fukata, Y.1
Amano, M.2
Kaibuchi, K.3
-
34
-
-
0035955345
-
Involvement of phosphorylation of myosin phosphatase by ROCK in trabecular meshwork and ciliary muscle contraction
-
Fukiage, C., Mizutani, K., Kawamoto, Y., Azuma, M., Shearer, T.R., Involvement of phosphorylation of myosin phosphatase by ROCK in trabecular meshwork and ciliary muscle contraction. Biochem. Biophys. Res. Commun. 288 (2001), 296–300.
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.288
, pp. 296-300
-
-
Fukiage, C.1
Mizutani, K.2
Kawamoto, Y.3
Azuma, M.4
Shearer, T.R.5
-
35
-
-
59449100394
-
The effect of the Rho-associated protein kinase inhibitor, HA-1077, in the rabbit ocular hypertension model induced by water loading
-
Fukunaga, T., Ikesugi, K., Nishio, M., Sugimoto, M., Sasoh, M., Hidaka, H., Uji, Y., The effect of the Rho-associated protein kinase inhibitor, HA-1077, in the rabbit ocular hypertension model induced by water loading. Curr. eye Res. 34 (2009), 42–47.
-
(2009)
Curr. eye Res.
, vol.34
, pp. 42-47
-
-
Fukunaga, T.1
Ikesugi, K.2
Nishio, M.3
Sugimoto, M.4
Sasoh, M.5
Hidaka, H.6
Uji, Y.7
-
36
-
-
0024474249
-
Prostaglandin F2 alpha increases uveoscleral outflow in the cynomolgus monkey
-
Gabelt, B.T., Kaufman, P.L., Prostaglandin F2 alpha increases uveoscleral outflow in the cynomolgus monkey. Exp. eye Res. 49 (1989), 389–402.
-
(1989)
Exp. eye Res.
, vol.49
, pp. 389-402
-
-
Gabelt, B.T.1
Kaufman, P.L.2
-
37
-
-
21744456373
-
Changes in aqueous humor dynamics with age and glaucoma
-
Gabelt, B.T., Kaufman, P.L., Changes in aqueous humor dynamics with age and glaucoma. Prog. Retin Eye Res. 24 (2005), 612–637.
-
(2005)
Prog. Retin Eye Res.
, vol.24
, pp. 612-637
-
-
Gabelt, B.T.1
Kaufman, P.L.2
-
38
-
-
84898722360
-
The role of integrins in the trabecular meshwork. Journal of ocular pharmacology and therapeutics
-
Gagen, D., Faralli, J.A., Filla, M.S., Peters, D.M., The role of integrins in the trabecular meshwork. Journal of ocular pharmacology and therapeutics. official J. Assoc. Ocular Pharmacol. Ther. 30 (2014), 110–120.
-
(2014)
official J. Assoc. Ocular Pharmacol. Ther.
, vol.30
, pp. 110-120
-
-
Gagen, D.1
Faralli, J.A.2
Filla, M.S.3
Peters, D.M.4
-
40
-
-
84922102262
-
Ripasudil: first global approval
-
Garnock-Jones, K.P., Ripasudil: first global approval. Drugs 74 (2014), 2211–2215.
-
(2014)
Drugs
, vol.74
, pp. 2211-2215
-
-
Garnock-Jones, K.P.1
-
41
-
-
84867229440
-
Elevated levels of RhoA in the optic nerve head of human eyes with glaucoma
-
Goldhagen, B., Proia, A.D., Epstein, D.L., Rao, P.V., Elevated levels of RhoA in the optic nerve head of human eyes with glaucoma. J. glaucoma 21 (2012), 530–538.
-
(2012)
J. glaucoma
, vol.21
, pp. 530-538
-
-
Goldhagen, B.1
Proia, A.D.2
Epstein, D.L.3
Rao, P.V.4
-
42
-
-
84898732303
-
Morphological and hydrodynamic correlations with increasing outflow facility by rho-kinase inhibitor Y-27632
-
Gong, H., Yang, C.Y., Morphological and hydrodynamic correlations with increasing outflow facility by rho-kinase inhibitor Y-27632. J. Ocul. Pharmacol. Ther. 30 (2014), 143–153.
-
(2014)
J. Ocul. Pharmacol. Ther.
, vol.30
, pp. 143-153
-
-
Gong, H.1
Yang, C.Y.2
-
43
-
-
84898746117
-
Role of microRNAs in the trabecular meshwork
-
Gonzalez, P., Li, G., Qiu, J., Wu, J., Luna, C., Role of microRNAs in the trabecular meshwork. J. Ocul. Pharmacol. Ther. 30 (2014), 128–137.
-
(2014)
J. Ocul. Pharmacol. Ther.
, vol.30
, pp. 128-137
-
-
Gonzalez, P.1
Li, G.2
Qiu, J.3
Wu, J.4
Luna, C.5
-
44
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall, A., Rho GTPases and the actin cytoskeleton. Science 279 (1998), 509–514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
45
-
-
84870209800
-
Rho family GTPases
-
Hall, A., Rho family GTPases. Biochem. Soc. Trans. 40 (2012), 1378–1382.
-
(2012)
Biochem. Soc. Trans.
, vol.40
, pp. 1378-1382
-
-
Hall, A.1
-
46
-
-
77957272673
-
Rho and Ras GTPases in axon growth, guidance, and branching
-
Hall, A., Lalli, G., Rho and Ras GTPases in axon growth, guidance, and branching. Cold Spring Harb. Perspect. Biol., 2, 2010, a001818.
-
(2010)
Cold Spring Harb. Perspect. Biol.
, vol.2
, pp. a001818
-
-
Hall, A.1
Lalli, G.2
-
47
-
-
84920737997
-
Discovery and development of LX7101, a dual LIM-kinase and ROCK inhibitor for the treatment of glaucoma
-
Harrison, B.A., Almstead, Z.Y., Burgoon, H., Gardyan, M., Goodwin, N.C., Healy, J., Liu, Y., Mabon, R., Marinelli, B., Samala, L., Zhang, Y., Stouch, T.R., Whitlock, N.A., Gopinathan, S., McKnight, B., Wang, S., Patel, N., Wilson, A.G., Hamman, B.D., Rice, D.S., Rawlins, D.B., Discovery and development of LX7101, a dual LIM-kinase and ROCK inhibitor for the treatment of glaucoma. ACS Med. Chem. Lett. 6 (2015), 84–88.
-
(2015)
ACS Med. Chem. Lett.
, vol.6
, pp. 84-88
-
-
Harrison, B.A.1
Almstead, Z.Y.2
Burgoon, H.3
Gardyan, M.4
Goodwin, N.C.5
Healy, J.6
Liu, Y.7
Mabon, R.8
Marinelli, B.9
Samala, L.10
Zhang, Y.11
Stouch, T.R.12
Whitlock, N.A.13
Gopinathan, S.14
McKnight, B.15
Wang, S.16
Patel, N.17
Wilson, A.G.18
Hamman, B.D.19
Rice, D.S.20
Rawlins, D.B.21
more..
-
48
-
-
71049125741
-
Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma
-
Harrison, B.A., Whitlock, N.A., Voronkov, M.V., Almstead, Z.Y., Gu, K.J., Mabon, R., Gardyan, M., Hamman, B.D., Allen, J., Gopinathan, S., McKnight, B., Crist, M., Zhang, Y., Liu, Y., Courtney, L.F., Key, B., Zhou, J., Patel, N., Yates, P.W., Liu, Q., Wilson, A.G., Kimball, S.D., Crosson, C.E., Rice, D.S., Rawlins, D.B., Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma. J. Med. Chem. 52 (2009), 6515–6518.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 6515-6518
-
-
Harrison, B.A.1
Whitlock, N.A.2
Voronkov, M.V.3
Almstead, Z.Y.4
Gu, K.J.5
Mabon, R.6
Gardyan, M.7
Hamman, B.D.8
Allen, J.9
Gopinathan, S.10
McKnight, B.11
Crist, M.12
Zhang, Y.13
Liu, Y.14
Courtney, L.F.15
Key, B.16
Zhou, J.17
Patel, N.18
Yates, P.W.19
Liu, Q.20
Wilson, A.G.21
Kimball, S.D.22
Crosson, C.E.23
Rice, D.S.24
Rawlins, D.B.25
more..
-
49
-
-
84949769682
-
The function of rho-associated kinases ROCK1 and ROCK2 in the pathogenesis of cardiovascular disease
-
Hartmann, S., Ridley, A.J., Lutz, S., The function of rho-associated kinases ROCK1 and ROCK2 in the pathogenesis of cardiovascular disease. Front. Pharmacol., 6, 2015, 276.
-
(2015)
Front. Pharmacol.
, vol.6
, pp. 276
-
-
Hartmann, S.1
Ridley, A.J.2
Lutz, S.3
-
50
-
-
2942596469
-
The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals
-
Higginbotham, E.J., Gordon, M.O., Beiser, J.A., Drake, M.V., Bennett, G.R., Wilson, M.R., Kass, M.A., The Ocular Hypertension Treatment Study: topical medication delays or prevents primary open-angle glaucoma in African American individuals. Archives Ophthalmol. 122 (2004), 813–820.
-
(2004)
Archives Ophthalmol.
, vol.122
, pp. 813-820
-
-
Higginbotham, E.J.1
Gordon, M.O.2
Beiser, J.A.3
Drake, M.V.4
Bennett, G.R.5
Wilson, M.R.6
Kass, M.A.7
-
51
-
-
36448964140
-
Y-27632, a Rho-associated protein kinase inhibitor, attenuates neuronal cell death after transient retinal ischemia
-
Hirata, A., Inatani, M., Inomata, Y., Yonemura, N., Kawaji, T., Honjo, M., Tanihara, H., Y-27632, a Rho-associated protein kinase inhibitor, attenuates neuronal cell death after transient retinal ischemia. Graefes Arch. Clin. Exp. Ophthalmol. 246 (2008), 51–59.
-
(2008)
Graefes Arch. Clin. Exp. Ophthalmol.
, vol.246
, pp. 51-59
-
-
Hirata, A.1
Inatani, M.2
Inomata, Y.3
Yonemura, N.4
Kawaji, T.5
Honjo, M.6
Tanihara, H.7
-
52
-
-
0035164065
-
Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility
-
Honjo, M., Tanihara, H., Inatani, M., Kido, N., Sawamura, T., Yue, B.Y., Narumiya, S., Honda, Y., Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Investigative Ophthalmol. Vis. Sci. 42 (2001), 137–144.
-
(2001)
Investigative Ophthalmol. Vis. Sci.
, vol.42
, pp. 137-144
-
-
Honjo, M.1
Tanihara, H.2
Inatani, M.3
Kido, N.4
Sawamura, T.5
Yue, B.Y.6
Narumiya, S.7
Honda, Y.8
-
53
-
-
84924359656
-
Between Rho(k) and a hard place: the relation between vessel wall stiffness, endothelial contractility, and cardiovascular disease
-
Huveneers, S., Daemen, M.J., Hordijk, P.L., Between Rho(k) and a hard place: the relation between vessel wall stiffness, endothelial contractility, and cardiovascular disease. Circ. Res. 116 (2015), 895–908.
-
(2015)
Circ. Res.
, vol.116
, pp. 895-908
-
-
Huveneers, S.1
Daemen, M.J.2
Hordijk, P.L.3
-
54
-
-
84887410136
-
Rho-associated kinase inhibitors: a novel glaucoma therapy
-
Inoue, T., Tanihara, H., Rho-associated kinase inhibitors: a novel glaucoma therapy. Prog. Retin Eye Res. 37 (2013), 1–12.
-
(2013)
Prog. Retin Eye Res.
, vol.37
, pp. 1-12
-
-
Inoue, T.1
Tanihara, H.2
-
55
-
-
84904348321
-
Effects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits
-
Isobe, T., Mizuno, K., Kaneko, Y., Ohta, M., Koide, T., Tanabe, S., Effects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits. Curr. eye Res. 39 (2014), 813–822.
-
(2014)
Curr. eye Res.
, vol.39
, pp. 813-822
-
-
Isobe, T.1
Mizuno, K.2
Kaneko, Y.3
Ohta, M.4
Koide, T.5
Tanabe, S.6
-
56
-
-
84867382575
-
Connective tissue growth factor-mediated upregulation of neuromedin U expression in trabecular meshwork cells and its role in homeostasis of aqueous humor outflow
-
Iyer, P., Maddala, R., Pattabiraman, P.P., Rao, P.V., Connective tissue growth factor-mediated upregulation of neuromedin U expression in trabecular meshwork cells and its role in homeostasis of aqueous humor outflow. Investigative Ophthalmol. Vis. Sci. 53 (2012), 4952–4962.
-
(2012)
Investigative Ophthalmol. Vis. Sci.
, vol.53
, pp. 4952-4962
-
-
Iyer, P.1
Maddala, R.2
Pattabiraman, P.P.3
Rao, P.V.4
-
57
-
-
84922235747
-
Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions
-
Julian, L., Olson, M.F., Rho-associated coiled-coil containing kinases (ROCK): structure, regulation, and functions. Small GTPases, 5, 2014, e29846.
-
(2014)
Small GTPases
, vol.5
, pp. e29846
-
-
Julian, L.1
Olson, M.F.2
-
58
-
-
84861584720
-
Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork
-
Junglas, B., Kuespert, S., Seleem, A.A., Struller, T., Ullmann, S., Bosl, M., Bosserhoff, A., Kostler, J., Wagner, R., Tamm, E.R., Fuchshofer, R., Connective tissue growth factor causes glaucoma by modifying the actin cytoskeleton of the trabecular meshwork. Am. J. Pathol. 180 (2012), 2386–2403.
-
(2012)
Am. J. Pathol.
, vol.180
, pp. 2386-2403
-
-
Junglas, B.1
Kuespert, S.2
Seleem, A.A.3
Struller, T.4
Ullmann, S.5
Bosl, M.6
Bosserhoff, A.7
Kostler, J.8
Wagner, R.9
Tamm, E.R.10
Fuchshofer, R.11
-
59
-
-
84864292323
-
The effect of Rho-associated protein kinase inhibitor on monkey Schlemm's canal endothelial cells
-
Kameda, T., Inoue, T., Inatani, M., Fujimoto, T., Honjo, M., Kasaoka, N., Inoue-Mochita, M., Yoshimura, N., Tanihara, H., The effect of Rho-associated protein kinase inhibitor on monkey Schlemm's canal endothelial cells. Investigative Ophthalmol. Vis. Sci. 53 (2012), 3092–3103.
-
(2012)
Investigative Ophthalmol. Vis. Sci.
, vol.53
, pp. 3092-3103
-
-
Kameda, T.1
Inoue, T.2
Inatani, M.3
Fujimoto, T.4
Honjo, M.5
Kasaoka, N.6
Inoue-Mochita, M.7
Yoshimura, N.8
Tanihara, H.9
-
60
-
-
84955488006
-
Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells
-
Kaneko, Y., Ohta, M., Inoue, T., Mizuno, K., Isobe, T., Tanabe, S., Tanihara, H., Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm's canal endothelial cells. Sci. Rep., 6, 2016, 19640.
-
(2016)
Sci. Rep.
, vol.6
, pp. 19640
-
-
Kaneko, Y.1
Ohta, M.2
Inoue, T.3
Mizuno, K.4
Isobe, T.5
Tanabe, S.6
Tanihara, H.7
-
61
-
-
22844448056
-
Incorporating the results of the ocular hypertension treatment study into clinical practice
-
Kass, M.A., Gordon, M.O., Kymes, S.M., Incorporating the results of the ocular hypertension treatment study into clinical practice. Archives Ophthalmol. 123 (2005), 1021–1022.
-
(2005)
Archives Ophthalmol.
, vol.123
, pp. 1021-1022
-
-
Kass, M.A.1
Gordon, M.O.2
Kymes, S.M.3
-
62
-
-
0017360761
-
Cytochalasin B reversibly increases outflow facility in the eye of the cynomolgus monkey
-
Kaufman, P.L., Barany, E.H., Cytochalasin B reversibly increases outflow facility in the eye of the cynomolgus monkey. Investigative Ophthalmol. Vis. Sci. 16 (1977), 47–53.
-
(1977)
Investigative Ophthalmol. Vis. Sci.
, vol.16
, pp. 47-53
-
-
Kaufman, P.L.1
Barany, E.H.2
-
63
-
-
64249132761
-
Extracellular matrix turnover and outflow resistance
-
Keller, K.E., Aga, M., Bradley, J.M., Kelley, M.J., Acott, T.S., Extracellular matrix turnover and outflow resistance. Exp. eye Res. 88 (2009), 676–682.
-
(2009)
Exp. eye Res.
, vol.88
, pp. 676-682
-
-
Keller, K.E.1
Aga, M.2
Bradley, J.M.3
Kelley, M.J.4
Acott, T.S.5
-
64
-
-
84928166250
-
Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits
-
Kiel, J.W., Kopczynski, C.C., Effect of AR-13324 on episcleral venous pressure in Dutch belted rabbits. J. Ocul. Pharmacol. Ther. 31 (2015), 146–151.
-
(2015)
J. Ocul. Pharmacol. Ther.
, vol.31
, pp. 146-151
-
-
Kiel, J.W.1
Kopczynski, C.C.2
-
65
-
-
9444242736
-
Regulation of myosin phosphatase by rho and rho-associated kinase (Rho-kinase)
-
Kimura, K., Ito, M., Amano, M., Chihara, K., Fukata, Y., Nakafuku, M., Yamamori, B., Feng, J., Nakano, T., Okawa, K., Iwamatsu, A., Kaibuchi, K., Regulation of myosin phosphatase by rho and rho-associated kinase (Rho-kinase). Science 273 (1996), 245–248.
-
(1996)
Science
, vol.273
, pp. 245-248
-
-
Kimura, K.1
Ito, M.2
Amano, M.3
Chihara, K.4
Fukata, Y.5
Nakafuku, M.6
Yamamori, B.7
Feng, J.8
Nakano, T.9
Okawa, K.10
Iwamatsu, A.11
Kaibuchi, K.12
-
66
-
-
3242655543
-
Involvement of RhoA and possible neuroprotective effect of fasudil, a Rho kinase inhibitor, in NMDA-induced neurotoxicity in the rat retina
-
Kitaoka, Y., Kitaoka, Y., Kumai, T., Lam, T.T., Kuribayashi, K., Isenoumi, K., Munemasa, Y., Motoki, M., Kobayashi, S., Ueno, S., Involvement of RhoA and possible neuroprotective effect of fasudil, a Rho kinase inhibitor, in NMDA-induced neurotoxicity in the rat retina. Brain Res. 1018 (2004), 111–118.
-
(2004)
Brain Res.
, vol.1018
, pp. 111-118
-
-
Kitaoka, Y.1
Kitaoka, Y.2
Kumai, T.3
Lam, T.T.4
Kuribayashi, K.5
Isenoumi, K.6
Munemasa, Y.7
Motoki, M.8
Kobayashi, S.9
Ueno, S.10
-
67
-
-
84916241169
-
The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis
-
Knipe, R.S., Tager, A.M., Liao, J.K., The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis. Pharmacol. Rev. 67 (2015), 103–117.
-
(2015)
Pharmacol. Rev.
, vol.67
, pp. 103-117
-
-
Knipe, R.S.1
Tager, A.M.2
Liao, J.K.3
-
68
-
-
84908346144
-
Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells
-
Koch, J.C., Tonges, L., Michel, U., Bahr, M., Lingor, P., Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells. Front. Cell Neurosci., 8, 2014, 273.
-
(2014)
Front. Cell Neurosci.
, vol.8
, pp. 273
-
-
Koch, J.C.1
Tonges, L.2
Michel, U.3
Bahr, M.4
Lingor, P.5
-
69
-
-
84913540772
-
Rho-kinase as a therapeutic target in vascular diseases: striking nitric oxide signaling
-
Kolluru, G.K., Majumder, S., Chatterjee, S., Rho-kinase as a therapeutic target in vascular diseases: striking nitric oxide signaling. Nitric Oxide 43 (2014), 45–54.
-
(2014)
Nitric Oxide
, vol.43
, pp. 45-54
-
-
Kolluru, G.K.1
Majumder, S.2
Chatterjee, S.3
-
70
-
-
79251604992
-
Rho GTPase-mediated cytoskeletal organization in Schlemm's canal cells play a critical role in the regulation of aqueous humor outflow facility
-
Kumar, J., Epstein, D.L., Rho GTPase-mediated cytoskeletal organization in Schlemm's canal cells play a critical role in the regulation of aqueous humor outflow facility. J. Cell Biochem. 112 (2011), 600–606.
-
(2011)
J. Cell Biochem.
, vol.112
, pp. 600-606
-
-
Kumar, J.1
Epstein, D.L.2
-
71
-
-
62349090894
-
Primary open-angle glaucoma
-
Kwon, Y.H., Fingert, J.H., Kuehn, M.H., Alward, W.L., Primary open-angle glaucoma. N. Engl. J. Med. 360 (2009), 1113–1124.
-
(2009)
N. Engl. J. Med.
, vol.360
, pp. 1113-1124
-
-
Kwon, Y.H.1
Fingert, J.H.2
Kuehn, M.H.3
Alward, W.L.4
-
72
-
-
79952157467
-
Emerging drugs for ocular hypertension
-
Lee, A.J., Goldberg, I., Emerging drugs for ocular hypertension. Expert Opin. Emerg. Drugs 16 (2011), 137–161.
-
(2011)
Expert Opin. Emerg. Drugs
, vol.16
, pp. 137-161
-
-
Lee, A.J.1
Goldberg, I.2
-
73
-
-
84927574746
-
Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers
-
980–985 e981
-
Levy, B., Ramirez, N., Novack, G.D., Kopczynski, C., Ocular hypotensive safety and systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am. J. Ophthalmol., 159, 2015 980–985 e981.
-
(2015)
Am. J. Ophthalmol.
, vol.159
-
-
Levy, B.1
Ramirez, N.2
Novack, G.D.3
Kopczynski, C.4
-
74
-
-
84959519750
-
Fixed-dose combination of AR-13324 and latanoprost: a double-masked, 28-day, randomised, controlled study in patients with open-angle glaucoma or ocular hypertension
-
Lewis, R.A., Levy, B., Ramirez, N., C.K, C., Usner, D.W., Novack, G.D., Group, P.C.S., Fixed-dose combination of AR-13324 and latanoprost: a double-masked, 28-day, randomised, controlled study in patients with open-angle glaucoma or ocular hypertension. Br. J. Ophthalmol. 100 (2016), 339–344.
-
(2016)
Br. J. Ophthalmol.
, vol.100
, pp. 339-344
-
-
Lewis, R.A.1
Levy, B.2
Ramirez, N.3
C.K, C.4
Usner, D.W.5
Novack, G.D.6
Group, P.C.S.7
-
75
-
-
84964649332
-
Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes
-
Li, G., Mukherjee, D., Navarro, I., Ashpole, N.E., Sherwood, J.M., Chang, J., Overby, D.R., Yuan, F., Gonzalez, P., Kopczynski, C.C., Farsiu, S., Stamer, W.D., Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes. Eur. J. Pharmacol., 2016.
-
(2016)
Eur. J. Pharmacol.
-
-
Li, G.1
Mukherjee, D.2
Navarro, I.3
Ashpole, N.E.4
Sherwood, J.M.5
Chang, J.6
Overby, D.R.7
Yuan, F.8
Gonzalez, P.9
Kopczynski, C.C.10
Farsiu, S.11
Stamer, W.D.12
-
76
-
-
84922967715
-
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
-
Liu, F., Lagares, D., Choi, K.M., Stopfer, L., Marinkovic, A., Vrbanac, V., Probst, C.K., Hiemer, S.E., Sisson, T.H., Horowitz, J.C., Rosas, I.O., Fredenburgh, L.E., Feghali-Bostwick, C., Varelas, X., Tager, A.M., Tschumperlin, D.J., Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. Am. J. Physiol. Lung Cell Mol. Physiol. 308 (2015), L344–L357.
-
(2015)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.308
, pp. L344-L357
-
-
Liu, F.1
Lagares, D.2
Choi, K.M.3
Stopfer, L.4
Marinkovic, A.5
Vrbanac, V.6
Probst, C.K.7
Hiemer, S.E.8
Sisson, T.H.9
Horowitz, J.C.10
Rosas, I.O.11
Fredenburgh, L.E.12
Feghali-Bostwick, C.13
Varelas, X.14
Tager, A.M.15
Tschumperlin, D.J.16
-
77
-
-
84866528532
-
siRNA silencing of gene expression in trabecular meshwork: RhoA siRNA reduces IOP in mice
-
Liu, Q., Wu, K., Qiu, X., Yang, Y., Lin, X., Yu, M., siRNA silencing of gene expression in trabecular meshwork: RhoA siRNA reduces IOP in mice. Curr. Mol. Med. 12 (2012), 1015–1027.
-
(2012)
Curr. Mol. Med.
, vol.12
, pp. 1015-1027
-
-
Liu, Q.1
Wu, K.2
Qiu, X.3
Yang, Y.4
Lin, X.5
Yu, M.6
-
78
-
-
29244491953
-
The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes
-
Liu, X., Hu, Y., Filla, M.S., Gabelt, B.T., Peters, D.M., Brandt, C.R., Kaufman, P.L., The effect of C3 transgene expression on actin and cellular adhesions in cultured human trabecular meshwork cells and on outflow facility in organ cultured monkey eyes. Mol. Vis. 11 (2005), 1112–1121.
-
(2005)
Mol. Vis.
, vol.11
, pp. 1112-1121
-
-
Liu, X.1
Hu, Y.2
Filla, M.S.3
Gabelt, B.T.4
Peters, D.M.5
Brandt, C.R.6
Kaufman, P.L.7
-
79
-
-
84942900076
-
Rho kinases in Health and disease: from basic science to translational research
-
Loirand, G., Rho kinases in Health and disease: from basic science to translational research. Pharmacol. Rev. 67 (2015), 1074–1095.
-
(2015)
Pharmacol. Rev.
, vol.67
, pp. 1074-1095
-
-
Loirand, G.1
-
80
-
-
48249089601
-
Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors
-
Lukas, T.J., Miao, H., Chen, L., Riordan, S.M., Li, W., Crabb, A.M., Wise, A., Du, P., Lin, S.M., Hernandez, M.R., Susceptibility to glaucoma: differential comparison of the astrocyte transcriptome from glaucomatous African American and Caucasian American donors. Genome Biol., 9, 2008, R111.
-
(2008)
Genome Biol.
, vol.9
, pp. R111
-
-
Lukas, T.J.1
Miao, H.2
Chen, L.3
Riordan, S.M.4
Li, W.5
Crabb, A.M.6
Wise, A.7
Du, P.8
Lin, S.M.9
Hernandez, M.R.10
-
81
-
-
84871262532
-
Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c
-
Luna, C., Li, G., Huang, J., Qiu, J., Wu, J., Yuan, F., Epstein, D.L., Gonzalez, P., Regulation of trabecular meshwork cell contraction and intraocular pressure by miR-200c. PloS one, 7, 2012, e51688.
-
(2012)
PloS one
, vol.7
, pp. e51688
-
-
Luna, C.1
Li, G.2
Huang, J.3
Qiu, J.4
Wu, J.5
Yuan, F.6
Epstein, D.L.7
Gonzalez, P.8
-
82
-
-
0037900257
-
Functional morphology of the trabecular meshwork in primate eyes
-
Lutjen-Drecoll, E., Functional morphology of the trabecular meshwork in primate eyes. Prog. Retin Eye Res. 18 (1999), 91–119.
-
(1999)
Prog. Retin Eye Res.
, vol.18
, pp. 91-119
-
-
Lutjen-Drecoll, E.1
-
83
-
-
3142688966
-
Role of lysophospholipid growth factors in the modulation of aqueous humor outflow facility
-
Mettu, P.S., Deng, P.F., Misra, U.K., Gawdi, G., Epstein, D.L., Rao, P.V., Role of lysophospholipid growth factors in the modulation of aqueous humor outflow facility. Investigative Ophthalmol. Vis. Sci. 45 (2004), 2263–2271.
-
(2004)
Investigative Ophthalmol. Vis. Sci.
, vol.45
, pp. 2263-2271
-
-
Mettu, P.S.1
Deng, P.F.2
Misra, U.K.3
Gawdi, G.4
Epstein, D.L.5
Rao, P.V.6
-
84
-
-
33744944072
-
Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism
-
Mimura, F., Yamagishi, S., Arimura, N., Fujitani, M., Kubo, T., Kaibuchi, K., Yamashita, T., Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism. J. Biol. Chem. 281 (2006), 15970–15979.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 15970-15979
-
-
Mimura, F.1
Yamagishi, S.2
Arimura, N.3
Fujitani, M.4
Kubo, T.5
Kaibuchi, K.6
Yamashita, T.7
-
85
-
-
84867182034
-
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
-
Mo, J.S., Yu, F.X., Gong, R., Brown, J.H., Guan, K.L., Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs). Genes Dev. 26 (2012), 2138–2143.
-
(2012)
Genes Dev.
, vol.26
, pp. 2138-2143
-
-
Mo, J.S.1
Yu, F.X.2
Gong, R.3
Brown, J.H.4
Guan, K.L.5
-
86
-
-
1842529005
-
The Rho-ROCK system as a new therapeutic target for preventing interstitial fibrosis
-
Moriyama, T., Nagatoya, K., The Rho-ROCK system as a new therapeutic target for preventing interstitial fibrosis. Drug news Perspect. 17 (2004), 29–34.
-
(2004)
Drug news Perspect.
, vol.17
, pp. 29-34
-
-
Moriyama, T.1
Nagatoya, K.2
-
87
-
-
18944372230
-
Rho kinase, a promising drug target for neurological disorders
-
Mueller, B.K., Mack, H., Teusch, N., Rho kinase, a promising drug target for neurological disorders. Nat. Rev. Drug Discov. 4 (2005), 387–398.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 387-398
-
-
Mueller, B.K.1
Mack, H.2
Teusch, N.3
-
88
-
-
17744397579
-
Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes
-
Nakajima, E., Nakajima, T., Minagawa, Y., Shearer, T.R., Azuma, M., Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes. J. Pharm. Sci. 94 (2005), 701–708.
-
(2005)
J. Pharm. Sci.
, vol.94
, pp. 701-708
-
-
Nakajima, E.1
Nakajima, T.2
Minagawa, Y.3
Shearer, T.R.4
Azuma, M.5
-
89
-
-
0036845687
-
Signaling mechanism of TGF-beta1-induced collagen contraction mediated by bovine trabecular meshwork cells
-
Nakamura, Y., Hirano, S., Suzuki, K., Seki, K., Sagara, T., Nishida, T., Signaling mechanism of TGF-beta1-induced collagen contraction mediated by bovine trabecular meshwork cells. Investigative Ophthalmol. Vis. Sci. 43 (2002), 3465–3472.
-
(2002)
Investigative Ophthalmol. Vis. Sci.
, vol.43
, pp. 3465-3472
-
-
Nakamura, Y.1
Hirano, S.2
Suzuki, K.3
Seki, K.4
Sagara, T.5
Nishida, T.6
-
90
-
-
67649644686
-
The effect of the H-1152P, a potent Rho-associated coiled coil-formed protein kinase inhibitor, in rabbit normal and ocular hypertensive eyes
-
Nishio, M., Fukunaga, T., Sugimoto, M., Ikesugi, K., Sumi, K., Hidaka, H., Uji, Y., The effect of the H-1152P, a potent Rho-associated coiled coil-formed protein kinase inhibitor, in rabbit normal and ocular hypertensive eyes. Curr. eye Res. 34 (2009), 282–286.
-
(2009)
Curr. eye Res.
, vol.34
, pp. 282-286
-
-
Nishio, M.1
Fukunaga, T.2
Sugimoto, M.3
Ikesugi, K.4
Sumi, K.5
Hidaka, H.6
Uji, Y.7
-
91
-
-
0030747132
-
Endothelin-like immunoreactivity in aqueous humor of patients with primary open-angle glaucoma and cataract
-
Noske, W., Hensen, J., Wiederholt, M., Endothelin-like immunoreactivity in aqueous humor of patients with primary open-angle glaucoma and cataract. Graefes Arch. Clin. Exp. Ophthalmol. 235 (1997), 551–552.
-
(1997)
Graefes Arch. Clin. Exp. Ophthalmol.
, vol.235
, pp. 551-552
-
-
Noske, W.1
Hensen, J.2
Wiederholt, M.3
-
92
-
-
84955619852
-
The ocular hypotensive efficacy of topical fasudil, a rho-associated protein kinase inhibitor, in patients with end-stage glaucoma
-
Pakravan, M., Beni, A.N., Ghahari, E., Varshochian, R., Yazdani, S., Esfandiari, H., Ahmadieh, H., The ocular hypotensive efficacy of topical fasudil, a rho-associated protein kinase inhibitor, in patients with end-stage glaucoma. Am. J. Ther., 2016.
-
(2016)
Am. J. Ther.
-
-
Pakravan, M.1
Beni, A.N.2
Ghahari, E.3
Varshochian, R.4
Yazdani, S.5
Esfandiari, H.6
Ahmadieh, H.7
-
93
-
-
84929173785
-
Elevated intraocular pressure induces Rho GTPase mediated contractile signaling in the trabecular meshwork
-
Pattabiraman, P.P., Inoue, T., Rao, P.V., Elevated intraocular pressure induces Rho GTPase mediated contractile signaling in the trabecular meshwork. Exp. eye Res. 136 (2015), 29–33.
-
(2015)
Exp. eye Res.
, vol.136
, pp. 29-33
-
-
Pattabiraman, P.P.1
Inoue, T.2
Rao, P.V.3
-
94
-
-
84896538885
-
Regulation of plasticity and fibrogenic activity of trabecular meshwork cells by Rho GTPase signaling
-
Pattabiraman, P.P., Maddala, R., Rao, P.V., Regulation of plasticity and fibrogenic activity of trabecular meshwork cells by Rho GTPase signaling. J. Cell Physiol. 229 (2014), 927–942.
-
(2014)
J. Cell Physiol.
, vol.229
, pp. 927-942
-
-
Pattabiraman, P.P.1
Maddala, R.2
Rao, P.V.3
-
95
-
-
77749254700
-
Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells
-
Pattabiraman, P.P., Rao, P.V., Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells. Am. J. Physiol. Cell Physiol. 298 (2010), C749–C763.
-
(2010)
Am. J. Physiol. Cell Physiol.
, vol.298
, pp. C749-C763
-
-
Pattabiraman, P.P.1
Rao, P.V.2
-
96
-
-
84922311604
-
RhoA GTPase-induced ocular hypertension in a rodent model is associated with increased fibrogenic activity in the trabecular meshwork
-
Pattabiraman, P.P., Rinkoski, T., Poeschla, E., Proia, A., Challa, P., Rao, P.V., RhoA GTPase-induced ocular hypertension in a rodent model is associated with increased fibrogenic activity in the trabecular meshwork. Am. J. Pathol. 185 (2015), 496–512.
-
(2015)
Am. J. Pathol.
, vol.185
, pp. 496-512
-
-
Pattabiraman, P.P.1
Rinkoski, T.2
Poeschla, E.3
Proia, A.4
Challa, P.5
Rao, P.V.6
-
97
-
-
84953432325
-
Rho GTPase signaling promotes constitutive expression and release of TGF-beta2 by human trabecular meshwork cells
-
Pervan, C.L., Lautz, J.D., Blitzer, A.L., Langert, K.A., Stubbs, E.B. Jr., Rho GTPase signaling promotes constitutive expression and release of TGF-beta2 by human trabecular meshwork cells. Exp. eye Res. 146 (2015), 95–102.
-
(2015)
Exp. eye Res.
, vol.146
, pp. 95-102
-
-
Pervan, C.L.1
Lautz, J.D.2
Blitzer, A.L.3
Langert, K.A.4
Stubbs, E.B.5
-
98
-
-
0032994540
-
Latrunculin-A increases outflow facility in the monkey
-
Peterson, J.A., Tian, B., Bershadsky, A.D., Volberg, T., Gangnon, R.E., Spector, I., Geiger, B., Kaufman, P.L., Latrunculin-A increases outflow facility in the monkey. Investigative Ophthalmol. Vis. Sci. 40 (1999), 931–941.
-
(1999)
Investigative Ophthalmol. Vis. Sci.
, vol.40
, pp. 931-941
-
-
Peterson, J.A.1
Tian, B.2
Bershadsky, A.D.3
Volberg, T.4
Gangnon, R.E.5
Spector, I.6
Geiger, B.7
Kaufman, P.L.8
-
99
-
-
79954621581
-
Glaucoma
-
Quigley, H.A., Glaucoma. Lancet 377 (2011), 1367–1377.
-
(2011)
Lancet
, vol.377
, pp. 1367-1377
-
-
Quigley, H.A.1
-
100
-
-
33644655886
-
The number of people with glaucoma worldwide in 2010 and 2020
-
Quigley, H.A., Broman, A.T., The number of people with glaucoma worldwide in 2010 and 2020. Br. J. Ophthalmol. 90 (2006), 262–267.
-
(2006)
Br. J. Ophthalmol.
, vol.90
, pp. 262-267
-
-
Quigley, H.A.1
Broman, A.T.2
-
101
-
-
84939856414
-
Dexamethasone stiffens trabecular meshwork, trabecular meshwork cells, and matrix
-
Raghunathan, V.K., Morgan, J.T., Park, S.A., Weber, D., Phinney, B.S., Murphy, C.J., Russell, P., Dexamethasone stiffens trabecular meshwork, trabecular meshwork cells, and matrix. Investigative Ophthalmol. Vis. Sci. 56 (2015), 4447–4459.
-
(2015)
Investigative Ophthalmol. Vis. Sci.
, vol.56
, pp. 4447-4459
-
-
Raghunathan, V.K.1
Morgan, J.T.2
Park, S.A.3
Weber, D.4
Phinney, B.S.5
Murphy, C.J.6
Russell, P.7
-
102
-
-
79960729300
-
Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells
-
Ramachandran, C., Patil, R.V., Combrink, K., Sharif, N.A., Srinivas, S.P., Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells. Mol. Vis. 17 (2011), 1877–1890.
-
(2011)
Mol. Vis.
, vol.17
, pp. 1877-1890
-
-
Ramachandran, C.1
Patil, R.V.2
Combrink, K.3
Sharif, N.A.4
Srinivas, S.P.5
-
103
-
-
79955933043
-
Effect of elevated intracellular cAMP levels on actomyosin contraction in bovine trabecular meshwork cells
-
Ramachandran, C., Patil, R.V., Sharif, N.A., Srinivas, S.P., Effect of elevated intracellular cAMP levels on actomyosin contraction in bovine trabecular meshwork cells. Investigative Ophthalmol. Vis. Sci. 52 (2011), 1474–1485.
-
(2011)
Investigative Ophthalmol. Vis. Sci.
, vol.52
, pp. 1474-1485
-
-
Ramachandran, C.1
Patil, R.V.2
Sharif, N.A.3
Srinivas, S.P.4
-
104
-
-
24144445945
-
Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow
-
Rao, P.V., Deng, P., Maddala, R., Epstein, D.L., Li, C.Y., Shimokawa, H., Expression of dominant negative Rho-binding domain of Rho-kinase in organ cultured human eye anterior segments increases aqueous humor outflow. Mol. Vis. 11 (2005), 288–297.
-
(2005)
Mol. Vis.
, vol.11
, pp. 288-297
-
-
Rao, P.V.1
Deng, P.2
Maddala, R.3
Epstein, D.L.4
Li, C.Y.5
Shimokawa, H.6
-
105
-
-
12744252830
-
Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility
-
Rao, P.V., Deng, P., Sasaki, Y., Epstein, D.L., Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility. Exp. eye Res. 80 (2005), 197–206.
-
(2005)
Exp. eye Res.
, vol.80
, pp. 197-206
-
-
Rao, P.V.1
Deng, P.2
Sasaki, Y.3
Epstein, D.L.4
-
106
-
-
0035066006
-
Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632
-
Rao, P.V., Deng, P.F., Kumar, J., Epstein, D.L., Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. Investigative Ophthalmol. Vis. Sci. 42 (2001), 1029–1037.
-
(2001)
Investigative Ophthalmol. Vis. Sci.
, vol.42
, pp. 1029-1037
-
-
Rao, P.V.1
Deng, P.F.2
Kumar, J.3
Epstein, D.L.4
-
107
-
-
47249097461
-
Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork
-
Rao, P.V., Peterson, Y.K., Inoue, T., Casey, P.J., Effects of pharmacologic inhibition of protein geranylgeranyltransferase type I on aqueous humor outflow through the trabecular meshwork. Investigative Ophthalmol. Vis. Sci. 49 (2008), 2464–2471.
-
(2008)
Investigative Ophthalmol. Vis. Sci.
, vol.49
, pp. 2464-2471
-
-
Rao, P.V.1
Peterson, Y.K.2
Inoue, T.3
Casey, P.J.4
-
108
-
-
34249694646
-
Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma
-
Rao, V.P., Epstein, D.L., Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. BioDrugs 21 (2007), 167–177.
-
(2007)
BioDrugs
, vol.21
, pp. 167-177
-
-
Rao, V.P.1
Epstein, D.L.2
-
109
-
-
0035575585
-
Rho family proteins: coordinating cell responses
-
Ridley, A.J., Rho family proteins: coordinating cell responses. Trends Cell Biol. 11 (2001), 471–477.
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 471-477
-
-
Ridley, A.J.1
-
110
-
-
84958568074
-
The outflow pathway: a tissue with morphological and functional unity
-
Sacca, S.C., Gandolfi, S., Bagnis, A., Manni, G., Damonte, G., Traverso, C.E., Izzotti, A., The outflow pathway: a tissue with morphological and functional unity. J. Cell Physiol. 231 (2016), 1876–1893.
-
(2016)
J. Cell Physiol.
, vol.231
, pp. 1876-1893
-
-
Sacca, S.C.1
Gandolfi, S.2
Bagnis, A.3
Manni, G.4
Damonte, G.5
Traverso, C.E.6
Izzotti, A.7
-
111
-
-
34247210251
-
A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats
-
Sagawa, H., Terasaki, H., Nakamura, M., Ichikawa, M., Yata, T., Tokita, Y., Watanabe, M., A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats. Exp. Neurol. 205 (2007), 230–240.
-
(2007)
Exp. Neurol.
, vol.205
, pp. 230-240
-
-
Sagawa, H.1
Terasaki, H.2
Nakamura, M.3
Ichikawa, M.4
Yata, T.5
Tokita, Y.6
Watanabe, M.7
-
112
-
-
84894438924
-
Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis
-
Sawada, N., Liao, J.K., Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis. Antioxid. Redox Signal 20 (2014), 1251–1267.
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 1251-1267
-
-
Sawada, N.1
Liao, J.K.2
-
113
-
-
27744503371
-
Episcleral venous pressure in untreated primary open-angle and normal-tension glaucoma
-
Selbach, J.M., Posielek, K., Steuhl, K.P., Kremmer, S., Episcleral venous pressure in untreated primary open-angle and normal-tension glaucoma. Ophthalmologica 219 (2005), 357–361.
-
(2005)
Ophthalmologica
, vol.219
, pp. 357-361
-
-
Selbach, J.M.1
Posielek, K.2
Steuhl, K.P.3
Kremmer, S.4
-
114
-
-
38049186811
-
Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells
-
Shen, X., Koga, T., Park, B.C., SundarRaj, N., Yue, B.Y., Rho GTPase and cAMP/protein kinase A signaling mediates myocilin-induced alterations in cultured human trabecular meshwork cells. J. Biol. Chem. 283 (2008), 603–612.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 603-612
-
-
Shen, X.1
Koga, T.2
Park, B.C.3
SundarRaj, N.4
Yue, B.Y.5
-
115
-
-
84955262072
-
RhoA/Rho-Kinase in the cardiovascular system
-
Shimokawa, H., Sunamura, S., Satoh, K., RhoA/Rho-Kinase in the cardiovascular system. Circ. Res. 118 (2016), 352–366.
-
(2016)
Circ. Res.
, vol.118
, pp. 352-366
-
-
Shimokawa, H.1
Sunamura, S.2
Satoh, K.3
-
116
-
-
84939611741
-
Viral vector effects on exoenzyme C3 transferase-mediated actin disruption and on outflow facility
-
Slauson, S.R., Peters, D.M., Schwinn, M.K., Kaufman, P.L., Gabelt, B.T., Brandt, C.R., Viral vector effects on exoenzyme C3 transferase-mediated actin disruption and on outflow facility. Investigative Ophthalmol. Vis. Sci. 56 (2015), 2431–2438.
-
(2015)
Investigative Ophthalmol. Vis. Sci.
, vol.56
, pp. 2431-2438
-
-
Slauson, S.R.1
Peters, D.M.2
Schwinn, M.K.3
Kaufman, P.L.4
Gabelt, B.T.5
Brandt, C.R.6
-
117
-
-
84878193974
-
The actin-MRTF-SRF gene regulatory axis and myofibroblast differentiation
-
Small, E.M., The actin-MRTF-SRF gene regulatory axis and myofibroblast differentiation. J. Cardiovasc Transl. Res. 5 (2012), 794–804.
-
(2012)
J. Cardiovasc Transl. Res.
, vol.5
, pp. 794-804
-
-
Small, E.M.1
-
118
-
-
0141751697
-
Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase
-
Somlyo, A.P., Somlyo, A.V., Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol. Rev. 83 (2003), 1325–1358.
-
(2003)
Physiol. Rev.
, vol.83
, pp. 1325-1358
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
119
-
-
23244442946
-
Effects of cholesterol-lowering statins on the aqueous humor outflow pathway
-
Song, J., Deng, P.F., Stinnett, S.S., Epstein, D.L., Rao, P.V., Effects of cholesterol-lowering statins on the aqueous humor outflow pathway. Investigative Ophthalmol. Vis. Sci. 46 (2005), 2424–2432.
-
(2005)
Investigative Ophthalmol. Vis. Sci.
, vol.46
, pp. 2424-2432
-
-
Song, J.1
Deng, P.F.2
Stinnett, S.S.3
Epstein, D.L.4
Rao, P.V.5
-
120
-
-
84897579255
-
Metabolic control of YAP and TAZ by the mevalonate pathway
-
Sorrentino, G., Ruggeri, N., Specchia, V., Cordenonsi, M., Mano, M., Dupont, S., Manfrin, A., Ingallina, E., Sommaggio, R., Piazza, S., Rosato, A., Piccolo, S., Del Sal, G., Metabolic control of YAP and TAZ by the mevalonate pathway. Nat. Cell Biol. 16 (2014), 357–366.
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 357-366
-
-
Sorrentino, G.1
Ruggeri, N.2
Specchia, V.3
Cordenonsi, M.4
Mano, M.5
Dupont, S.6
Manfrin, A.7
Ingallina, E.8
Sommaggio, R.9
Piazza, S.10
Rosato, A.11
Piccolo, S.12
Del Sal, G.13
-
121
-
-
84941992050
-
ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure
-
Springelkamp, H., Iglesias, A.I., Cuellar-Partida, G., Amin, N., Burdon, K.P., van Leeuwen, E.M., Gharahkhani, P., Mishra, A., van der Lee, S.J., Hewitt, A.W., Rivadeneira, F., Viswanathan, A.C., Wolfs, R.C., Martin, N.G., Ramdas, W.D., van Koolwijk, L.M., Pennell, C.E., Vingerling, J.R., Mountain, J.E., Uitterlinden, A.G., Hofman, A., Mitchell, P., Lemij, H.G., Wang, J.J., Klaver, C.C., Mackey, D.A., Craig, J.E., van Duijn, C.M., MacGregor, S., ARHGEF12 influences the risk of glaucoma by increasing intraocular pressure. Hum. Mol. Genet. 24 (2015), 2689–2699.
-
(2015)
Hum. Mol. Genet.
, vol.24
, pp. 2689-2699
-
-
Springelkamp, H.1
Iglesias, A.I.2
Cuellar-Partida, G.3
Amin, N.4
Burdon, K.P.5
van Leeuwen, E.M.6
Gharahkhani, P.7
Mishra, A.8
van der Lee, S.J.9
Hewitt, A.W.10
Rivadeneira, F.11
Viswanathan, A.C.12
Wolfs, R.C.13
Martin, N.G.14
Ramdas, W.D.15
van Koolwijk, L.M.16
Pennell, C.E.17
Vingerling, J.R.18
Mountain, J.E.19
Uitterlinden, A.G.20
Hofman, A.21
Mitchell, P.22
Lemij, H.G.23
Wang, J.J.24
Klaver, C.C.25
Mackey, D.A.26
Craig, J.E.27
van Duijn, C.M.28
MacGregor, S.29
more..
-
122
-
-
84857232483
-
Current understanding of conventional outflow dysfunction in glaucoma
-
Stamer, W.D., Acott, T.S., Current understanding of conventional outflow dysfunction in glaucoma. Curr. Opin. Ophthalmol. 23 (2012), 135–143.
-
(2012)
Curr. Opin. Ophthalmol.
, vol.23
, pp. 135-143
-
-
Stamer, W.D.1
Acott, T.S.2
-
123
-
-
84916198849
-
Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction
-
Stamer, W.D., Braakman, S.T., Zhou, E.H., Ethier, C.R., Fredberg, J.J., Overby, D.R., Johnson, M., Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction. Prog. Retin Eye Res. 44 (2015), 86–98.
-
(2015)
Prog. Retin Eye Res.
, vol.44
, pp. 86-98
-
-
Stamer, W.D.1
Braakman, S.T.2
Zhou, E.H.3
Ethier, C.R.4
Fredberg, J.J.5
Overby, D.R.6
Johnson, M.7
-
124
-
-
70350719236
-
Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes
-
Stamer, W.D., Read, A.T., Sumida, G.M., Ethier, C.R., Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes. Exp. eye Res. 89 (2009), 980–988.
-
(2009)
Exp. eye Res.
, vol.89
, pp. 980-988
-
-
Stamer, W.D.1
Read, A.T.2
Sumida, G.M.3
Ethier, C.R.4
-
125
-
-
14444283397
-
Identification of a gene that causes primary open angle glaucoma
-
Stone, E.M., Fingert, J.H., Alward, W.L., Nguyen, T.D., Polansky, J.R., Sunden, S.L., Nishimura, D., Clark, A.F., Nystuen, A., Nichols, B.E., Mackey, D.A., Ritch, R., Kalenak, J.W., Craven, E.R., Sheffield, V.C., Identification of a gene that causes primary open angle glaucoma. Science 275 (1997), 668–670.
-
(1997)
Science
, vol.275
, pp. 668-670
-
-
Stone, E.M.1
Fingert, J.H.2
Alward, W.L.3
Nguyen, T.D.4
Polansky, J.R.5
Sunden, S.L.6
Nishimura, D.7
Clark, A.F.8
Nystuen, A.9
Nichols, B.E.10
Mackey, D.A.11
Ritch, R.12
Kalenak, J.W.13
Craven, E.R.14
Sheffield, V.C.15
-
126
-
-
84978328533
-
Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma
-
Sturdivant, J.M., Royalty, S.M., Lin, C.W., Moore, L.A., Yingling, J.D., Laethem, C.L., Sherman, B., Heintzelman, G.R., Kopczynski, C.C., deLong, M.A., Discovery of the ROCK inhibitor netarsudil for the treatment of open-angle glaucoma. Bioorg. Med. Chem. Lett. 26 (2016), 2475–2480.
-
(2016)
Bioorg. Med. Chem. Lett.
, vol.26
, pp. 2475-2480
-
-
Sturdivant, J.M.1
Royalty, S.M.2
Lin, C.W.3
Moore, L.A.4
Yingling, J.D.5
Laethem, C.L.6
Sherman, B.7
Heintzelman, G.R.8
Kopczynski, C.C.9
deLong, M.A.10
-
127
-
-
79952230532
-
Effects of fasudil, a Rho-associated protein kinase inhibitor, on optic nerve head blood flow in rabbits
-
Sugiyama, T., Shibata, M., Kajiura, S., Okuno, T., Tonari, M., Oku, H., Ikeda, T., Effects of fasudil, a Rho-associated protein kinase inhibitor, on optic nerve head blood flow in rabbits. Investigative Ophthalmol. Vis. Sci. 52 (2011), 64–69.
-
(2011)
Investigative Ophthalmol. Vis. Sci.
, vol.52
, pp. 64-69
-
-
Sugiyama, T.1
Shibata, M.2
Kajiura, S.3
Okuno, T.4
Tonari, M.5
Oku, H.6
Ikeda, T.7
-
128
-
-
84893689250
-
IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys
-
Sumi, K., Inoue, Y., Nishio, M., Naito, Y., Hosoya, T., Suzuki, M., Hidaka, H., IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys. Bioorg. Med. Chem. Lett. 24 (2014), 831–834.
-
(2014)
Bioorg. Med. Chem. Lett.
, vol.24
, pp. 831-834
-
-
Sumi, K.1
Inoue, Y.2
Nishio, M.3
Naito, Y.4
Hosoya, T.5
Suzuki, M.6
Hidaka, H.7
-
129
-
-
79955561473
-
Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers
-
Sumida, G.M., Stamer, W.D., Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers. Investigative Ophthalmol. Vis. Sci. 51 (2010), 6633–6638.
-
(2010)
Investigative Ophthalmol. Vis. Sci.
, vol.51
, pp. 6633-6638
-
-
Sumida, G.M.1
Stamer, W.D.2
-
130
-
-
84897584374
-
Rho/ROCK pathway and neural regeneration: a potential therapeutic target for central nervous system and optic nerve damage
-
Tan, H.B., Zhong, Y.S., Cheng, Y., Shen, X., Rho/ROCK pathway and neural regeneration: a potential therapeutic target for central nervous system and optic nerve damage. Int. J. Ophthalmol. 4 (2011), 652–657.
-
(2011)
Int. J. Ophthalmol.
, vol.4
, pp. 652-657
-
-
Tan, H.B.1
Zhong, Y.S.2
Cheng, Y.3
Shen, X.4
-
131
-
-
84937721263
-
Additive intraocular pressure-lowering effects of the rho kinase inhibitor ripasudil (K-115) combined with timolol or latanoprost: a report of 2 randomized clinical trials
-
Tanihara, H., Inoue, T., Yamamoto, T., Kuwayama, Y., Abe, H., Suganami, H., Araie, M., Group, K.C.S., Additive intraocular pressure-lowering effects of the rho kinase inhibitor ripasudil (K-115) combined with timolol or latanoprost: a report of 2 randomized clinical trials. JAMA Ophthalmol. 133 (2015), 755–761.
-
(2015)
JAMA Ophthalmol.
, vol.133
, pp. 755-761
-
-
Tanihara, H.1
Inoue, T.2
Yamamoto, T.3
Kuwayama, Y.4
Abe, H.5
Suganami, H.6
Araie, M.7
Group, K.C.S.8
-
132
-
-
84908473395
-
Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis
-
Tham, Y.C., Li, X., Wong, T.Y., Quigley, H.A., Aung, T., Cheng, C.Y., Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 121 (2014), 2081–2090.
-
(2014)
Ophthalmology
, vol.121
, pp. 2081-2090
-
-
Tham, Y.C.1
Li, X.2
Wong, T.Y.3
Quigley, H.A.4
Aung, T.5
Cheng, C.Y.6
-
133
-
-
0033658373
-
Mediation of calcium-independent contraction in trabecular meshwork through protein kinase C and rho-A
-
Thieme, H., Nuskovski, M., Nass, J.U., Pleyer, U., Strauss, O., Wiederholt, M., Mediation of calcium-independent contraction in trabecular meshwork through protein kinase C and rho-A. Investigative Ophthalmol. Vis. Sci. 41 (2000), 4240–4246.
-
(2000)
Investigative Ophthalmol. Vis. Sci.
, vol.41
, pp. 4240-4246
-
-
Thieme, H.1
Nuskovski, M.2
Nass, J.U.3
Pleyer, U.4
Strauss, O.5
Wiederholt, M.6
-
134
-
-
0038450313
-
Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death
-
Thumkeo, D., Keel, J., Ishizaki, T., Hirose, M., Nonomura, K., Oshima, H., Oshima, M., Taketo, M.M., Narumiya, S., Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death. Mol. Cell Biol. 23 (2003), 5043–5055.
-
(2003)
Mol. Cell Biol.
, vol.23
, pp. 5043-5055
-
-
Thumkeo, D.1
Keel, J.2
Ishizaki, T.3
Hirose, M.4
Nonomura, K.5
Oshima, H.6
Oshima, M.7
Taketo, M.M.8
Narumiya, S.9
-
135
-
-
23844442551
-
ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo
-
Thumkeo, D., Shimizu, Y., Sakamoto, S., Yamada, S., Narumiya, S., ROCK-I and ROCK-II cooperatively regulate closure of eyelid and ventral body wall in mouse embryo. Genes Cells 10 (2005), 825–834.
-
(2005)
Genes Cells
, vol.10
, pp. 825-834
-
-
Thumkeo, D.1
Shimizu, Y.2
Sakamoto, S.3
Yamada, S.4
Narumiya, S.5
-
136
-
-
84888437392
-
Physiological roles of Rho and Rho effectors in mammals
-
Thumkeo, D., Watanabe, S., Narumiya, S., Physiological roles of Rho and Rho effectors in mammals. Eur. J. Cell Biol. 92 (2013), 303–315.
-
(2013)
Eur. J. Cell Biol.
, vol.92
, pp. 303-315
-
-
Thumkeo, D.1
Watanabe, S.2
Narumiya, S.3
-
137
-
-
0033025113
-
Effect of staurosporine on outflow facility in monkeys
-
Tian, B., Gabelt, B.T., Kaufman, P.L., Effect of staurosporine on outflow facility in monkeys. Investigative Ophthalmol. Vis. Sci. 40 (1999), 1009–1011.
-
(1999)
Investigative Ophthalmol. Vis. Sci.
, vol.40
, pp. 1009-1011
-
-
Tian, B.1
Gabelt, B.T.2
Kaufman, P.L.3
-
138
-
-
0034066511
-
Cytoskeletal involvement in the regulation of aqueous humor outflow
-
Tian, B., Geiger, B., Epstein, D.L., Kaufman, P.L., Cytoskeletal involvement in the regulation of aqueous humor outflow. Investigative Ophthalmol. Vis. Sci. 41 (2000), 619–623.
-
(2000)
Investigative Ophthalmol. Vis. Sci.
, vol.41
, pp. 619-623
-
-
Tian, B.1
Geiger, B.2
Epstein, D.L.3
Kaufman, P.L.4
-
139
-
-
12744277365
-
Effects of the Rho kinase inhibitor Y-27632 and the phosphatase inhibitor calyculin A on outflow facility in monkeys
-
Tian, B., Kaufman, P.L., Effects of the Rho kinase inhibitor Y-27632 and the phosphatase inhibitor calyculin A on outflow facility in monkeys. Exp. eye Res. 80 (2005), 215–225.
-
(2005)
Exp. eye Res.
, vol.80
, pp. 215-225
-
-
Tian, B.1
Kaufman, P.L.2
-
140
-
-
0031708970
-
H-7 disrupts the actin cytoskeleton and increases outflow facility
-
Tian, B., Kaufman, P.L., Volberg, T., Gabelt, B.T., Geiger, B., H-7 disrupts the actin cytoskeleton and increases outflow facility. Archives Ophthalmol. 116 (1998), 633–643.
-
(1998)
Archives Ophthalmol.
, vol.116
, pp. 633-643
-
-
Tian, B.1
Kaufman, P.L.2
Volberg, T.3
Gabelt, B.T.4
Geiger, B.5
-
141
-
-
84947055095
-
Current perspective of neuroprotection and glaucoma
-
Tian, K., Shibata-Germanos, S., Pahlitzsch, M., Cordeiro, M.F., Current perspective of neuroprotection and glaucoma. Clin. Ophthalmol. 9 (2015), 2109–2118.
-
(2015)
Clin. Ophthalmol.
, vol.9
, pp. 2109-2118
-
-
Tian, K.1
Shibata-Germanos, S.2
Pahlitzsch, M.3
Cordeiro, M.F.4
-
142
-
-
80053320552
-
Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats
-
Tokushige, H., Waki, M., Takayama, Y., Tanihara, H., Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats. Curr. eye Res. 36 (2011), 964–970.
-
(2011)
Curr. eye Res.
, vol.36
, pp. 964-970
-
-
Tokushige, H.1
Waki, M.2
Takayama, Y.3
Tanihara, H.4
-
143
-
-
0032450986
-
Regulation of SRF activity by Rho family GTPases
-
Treisman, R., Alberts, A.S., Sahai, E., Regulation of SRF activity by Rho family GTPases. Cold Spring Harb. Symp. Quant. Biol. 63 (1998), 643–651.
-
(1998)
Cold Spring Harb. Symp. Quant. Biol.
, vol.63
, pp. 643-651
-
-
Treisman, R.1
Alberts, A.S.2
Sahai, E.3
-
144
-
-
0028592628
-
Aqueous humor in glaucomatous eyes contains an increased level of TGF-beta 2
-
Tripathi, R.C., Li, J., Chan, W.F., Tripathi, B.J., Aqueous humor in glaucomatous eyes contains an increased level of TGF-beta 2. Exp. eye Res. 59 (1994), 723–727.
-
(1994)
Exp. eye Res.
, vol.59
, pp. 723-727
-
-
Tripathi, R.C.1
Li, J.2
Chan, W.F.3
Tripathi, B.J.4
-
145
-
-
84903648153
-
Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription
-
Tsou, P.S., Haak, A.J., Khanna, D., Neubig, R.R., Cellular mechanisms of tissue fibrosis. 8. Current and future drug targets in fibrosis: focus on Rho GTPase-regulated gene transcription. Am. J. Physiol. Cell Physiol. 307 (2014), C2–C13.
-
(2014)
Am. J. Physiol. Cell Physiol.
, vol.307
, pp. C2-C13
-
-
Tsou, P.S.1
Haak, A.J.2
Khanna, D.3
Neubig, R.R.4
-
146
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
Uehata, M., Ishizaki, T., Satoh, H., Ono, T., Kawahara, T., Morishita, T., Tamakawa, H., Yamagami, K., Inui, J., Maekawa, M., Narumiya, S., Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389 (1997), 990–994.
-
(1997)
Nature
, vol.389
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
Tamakawa, H.7
Yamagami, K.8
Inui, J.9
Maekawa, M.10
Narumiya, S.11
-
147
-
-
84938209755
-
Towards axonal regeneration and neuroprotection in glaucoma: rho kinase inhibitors as promising therapeutics
-
Van de Velde, S., De Groef, L., Stalmans, I., Moons, L., Van Hove, I., Towards axonal regeneration and neuroprotection in glaucoma: rho kinase inhibitors as promising therapeutics. Prog. Neurobiol. 131 (2015), 105–119.
-
(2015)
Prog. Neurobiol.
, vol.131
, pp. 105-119
-
-
Van de Velde, S.1
De Groef, L.2
Stalmans, I.3
Moons, L.4
Van Hove, I.5
-
148
-
-
84894099557
-
AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia
-
Van de Velde, S., Van Bergen, T., Sijnave, D., Hollanders, K., Castermans, K., Defert, O., Leysen, D., Vandewalle, E., Moons, L., Stalmans, I., AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia. Investigative Ophthalmol. Vis. Sci. 55 (2014), 1006–1016.
-
(2014)
Investigative Ophthalmol. Vis. Sci.
, vol.55
, pp. 1006-1016
-
-
Van de Velde, S.1
Van Bergen, T.2
Sijnave, D.3
Hollanders, K.4
Castermans, K.5
Defert, O.6
Leysen, D.7
Vandewalle, E.8
Moons, L.9
Stalmans, I.10
-
149
-
-
78549276562
-
Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway
-
Varma, H., Yamamoto, A., Sarantos, M.R., Hughes, R.E., Stockwell, B.R., Mutant huntingtin alters cell fate in response to microtubule depolymerization via the GEF-H1-RhoA-ERK pathway. J. Biol. Chem. 285 (2010), 37445–37457.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 37445-37457
-
-
Varma, H.1
Yamamoto, A.2
Sarantos, M.R.3
Hughes, R.E.4
Stockwell, B.R.5
-
150
-
-
0036974434
-
Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures
-
Vittitow, J.L., Garg, R., Rowlette, L.L., Epstein, D.L., O'Brien, E.T., Borras, T., Gene transfer of dominant-negative RhoA increases outflow facility in perfused human anterior segment cultures. Mol. Vis. 8 (2002), 32–44.
-
(2002)
Mol. Vis.
, vol.8
, pp. 32-44
-
-
Vittitow, J.L.1
Garg, R.2
Rowlette, L.L.3
Epstein, D.L.4
O'Brien, E.T.5
Borras, T.6
-
151
-
-
66849091262
-
Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin
-
Von Zee, C.L., Richards, M.P., Bu, P., Perlman, J.I., Stubbs, E.B. Jr., Increased RhoA and RhoB protein accumulation in cultured human trabecular meshwork cells by lovastatin. Investigative Ophthalmol. Vis. Sci. 50 (2009), 2816–2823.
-
(2009)
Investigative Ophthalmol. Vis. Sci.
, vol.50
, pp. 2816-2823
-
-
Von Zee, C.L.1
Richards, M.P.2
Bu, P.3
Perlman, J.I.4
Stubbs, E.B.5
-
152
-
-
0035726683
-
Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase
-
Waki, M., Yoshida, Y., Oka, T., Azuma, M., Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase. Curr. eye Res. 22 (2001), 470–474.
-
(2001)
Curr. eye Res.
, vol.22
, pp. 470-474
-
-
Waki, M.1
Yoshida, Y.2
Oka, T.3
Azuma, M.4
-
153
-
-
84924931005
-
Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes
-
Wang, R.F., Williamson, J.E., Kopczynski, C., Serle, J.B., Effect of 0.04% AR-13324, a ROCK, and norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J. glaucoma 24 (2015), 51–54.
-
(2015)
J. glaucoma
, vol.24
, pp. 51-54
-
-
Wang, R.F.1
Williamson, J.E.2
Kopczynski, C.3
Serle, J.B.4
-
154
-
-
2442643730
-
Primary open-angle glaucoma
-
Weinreb, R.N., Khaw, P.T., Primary open-angle glaucoma. Lancet 363 (2004), 1711–1720.
-
(2004)
Lancet
, vol.363
, pp. 1711-1720
-
-
Weinreb, R.N.1
Khaw, P.T.2
-
155
-
-
66249123108
-
Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK
-
Whitlock, N.A., Harrison, B., Mixon, T., Yu, X.Q., Wilson, A., Gerhardt, B., Eberhart, D.E., Abuin, A., Rice, D.S., Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK. J. Ocul. Pharmacol. Ther. 25 (2009), 187–194.
-
(2009)
J. Ocul. Pharmacol. Ther.
, vol.25
, pp. 187-194
-
-
Whitlock, N.A.1
Harrison, B.2
Mixon, T.3
Yu, X.Q.4
Wilson, A.5
Gerhardt, B.6
Eberhart, D.E.7
Abuin, A.8
Rice, D.S.9
-
156
-
-
0034002380
-
The regulation of trabecular meshwork and ciliary muscle contractility
-
Wiederholt, M., Thieme, H., Stumpff, F., The regulation of trabecular meshwork and ciliary muscle contractility. Prog. Retin Eye Res. 19 (2000), 271–295.
-
(2000)
Prog. Retin Eye Res.
, vol.19
, pp. 271-295
-
-
Wiederholt, M.1
Thieme, H.2
Stumpff, F.3
-
157
-
-
84936928505
-
Upregulation of Gem relates to retinal ganglion cells apoptosis after optic nerve crush in adult rats
-
Xu, F., Huang, H., Wu, Y., Lu, L., Jiang, L., Chen, L., Zeng, S., Li, L., Li, M., Upregulation of Gem relates to retinal ganglion cells apoptosis after optic nerve crush in adult rats. J. Mol. Histol. 45 (2014), 565–571.
-
(2014)
J. Mol. Histol.
, vol.45
, pp. 565-571
-
-
Xu, F.1
Huang, H.2
Wu, Y.3
Lu, L.4
Jiang, L.5
Chen, L.6
Zeng, S.7
Li, L.8
Li, M.9
-
158
-
-
84922103622
-
The novel Rho kinase (ROCK) inhibitor K-115: a new candidate drug for neuroprotective treatment in glaucoma
-
Yamamoto, K., Maruyama, K., Himori, N., Omodaka, K., Yokoyama, Y., Shiga, Y., Morin, R., Nakazawa, T., The novel Rho kinase (ROCK) inhibitor K-115: a new candidate drug for neuroprotective treatment in glaucoma. Investigative Ophthalmol. Vis. Sci. 55 (2014), 7126–7136.
-
(2014)
Investigative Ophthalmol. Vis. Sci.
, vol.55
, pp. 7126-7136
-
-
Yamamoto, K.1
Maruyama, K.2
Himori, N.3
Omodaka, K.4
Yokoyama, Y.5
Shiga, Y.6
Morin, R.7
Nakazawa, T.8
-
159
-
-
84943613368
-
Fasudil alleviates traumatic optic neuropathy by inhibiting Rho signaling pathway
-
Yu, J., Lan, S., Wang, R., Maier, A., Luan, X., Fasudil alleviates traumatic optic neuropathy by inhibiting Rho signaling pathway. Int. J. Clin. Exp. Med. 8 (2015), 13377–13382.
-
(2015)
Int. J. Clin. Exp. Med.
, vol.8
, pp. 13377-13382
-
-
Yu, J.1
Lan, S.2
Wang, R.3
Maier, A.4
Luan, X.5
-
160
-
-
84957442477
-
Fasudil, a rho-associated protein kinase inhibitor, attenuates traumatic retinal nerve injury in rabbits
-
Yu, J., Luan, X., Lan, S., Yan, B., Maier, A., Fasudil, a rho-associated protein kinase inhibitor, attenuates traumatic retinal nerve injury in rabbits. J. Mol. Neurosci. 58 (2016), 74–82.
-
(2016)
J. Mol. Neurosci.
, vol.58
, pp. 74-82
-
-
Yu, J.1
Luan, X.2
Lan, S.3
Yan, B.4
Maier, A.5
-
161
-
-
77952304751
-
Protein expression in human trabecular meshwork: downregulation of RhoGDI by dexamethasone in vitro
-
Yu, M., Sun, J., Peng, W., Chen, Z., Lin, X., Liu, X., Li, M., Wu, K., Protein expression in human trabecular meshwork: downregulation of RhoGDI by dexamethasone in vitro. Mol. Vis. 16 (2010), 213–223.
-
(2010)
Mol. Vis.
, vol.16
, pp. 213-223
-
-
Yu, M.1
Sun, J.2
Peng, W.3
Chen, Z.4
Lin, X.5
Liu, X.6
Li, M.7
Wu, K.8
-
162
-
-
84885079333
-
Dexamethasone induces cross-linked actin networks in trabecular meshwork cells through noncanonical wnt signaling
-
Yuan, Y., Call, M.K., Yuan, Y., Zhang, Y., Fischesser, K., Liu, C.Y., Kao, W.W., Dexamethasone induces cross-linked actin networks in trabecular meshwork cells through noncanonical wnt signaling. Investigative Ophthalmol. Vis. Sci. 54 (2013), 6502–6509.
-
(2013)
Investigative Ophthalmol. Vis. Sci.
, vol.54
, pp. 6502-6509
-
-
Yuan, Y.1
Call, M.K.2
Yuan, Y.3
Zhang, Y.4
Fischesser, K.5
Liu, C.Y.6
Kao, W.W.7
-
163
-
-
57349186040
-
Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork
-
Zhang, M., Maddala, R., Rao, P.V., Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork. Am. J. Physiol. Cell Physiol. 295 (2008), C1057–C1070.
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.295
, pp. C1057-C1070
-
-
Zhang, M.1
Maddala, R.2
Rao, P.V.3
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164
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84863577692
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Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow
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Zhou, E.H., Krishnan, R., Stamer, W.D., Perkumas, K.M., Rajendran, K., Nabhan, J.F., Lu, Q., Fredberg, J.J., Johnson, M., Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow. J. R. Soc. Interface 9 (2012), 1144–1155.
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(2012)
J. R. Soc. Interface
, vol.9
, pp. 1144-1155
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Zhou, E.H.1
Krishnan, R.2
Stamer, W.D.3
Perkumas, K.M.4
Rajendran, K.5
Nabhan, J.F.6
Lu, Q.7
Fredberg, J.J.8
Johnson, M.9
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