Fasudil, a Rho-Associated Protein Kinase Inhibitor, Attenuates Traumatic Retinal Nerve Injury in Rabbits

Journal of Molecular Neuroscience

Volumn 58, Issue 1, 2016, Pages 74-82

  Yu, Jianglong ^a,b   Luan, Xinping ^a   Lan, Shiying ^b   Yan, Baofeng ^a   Maier, Aba ^a  

^a XINJIANG MEDICAL UNIVERSITY   (China)

^b Department of Neurosurgery The People s Hospital of Xinjiang Bazhou Region   (China)

Author keywords

Apoptosis; Retinal ganglion cells; RhoA Rock signaling; Traumatic optic neuropathy

Indexed keywords

CASPASE 3; FASUDIL; PROTEIN BCL 2; RHO KINASE; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; PROTEIN KINASE INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN FILAMENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AXOPLASM; CELL VIABILITY; COLORIMETRY; CONTROLLED STUDY; FLOW CYTOMETRY; HYPOGLYCEMIA; HYPOXIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROENVIRONMENT; MICROTUBULE; MITOCHONDRION; MYELIN SHEATH; NONHUMAN; OPTIC NERVE INJURY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RETINA GANGLION CELL; RETINA INJURY; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; TRAUMATIC RETINAL NERVE INJURY; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; METABOLISM; OPTIC NERVE INJURIES; RABBITS AND HARES;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; APOPTOSIS; CELLS, CULTURED; MALE; OPTIC NERVE INJURIES; PROTEIN KINASE INHIBITORS; RABBITS; RETINAL GANGLION CELLS; RHOA GTP-BINDING PROTEIN;

EID: 84957442477     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-015-0691-6     Document Type: Article

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