Mechanical responsiveness of the endothelial cell of Schlemm's canal: Scope, variability and its potential role in controlling aqueous humour outflow

Journal of the Royal Society Interface

Volumn 9, Issue 71, 2012, Pages 1144-1155

  Zhou, E H ^a   Krishnan, R ^a,b   Stamer, W D ^c,d   Perkumas, K M ^c   Rajendran, K ^b   Nabhan, J F ^a   Lu, Q ^a   Fredberg, J J ^a   Johnson, M ^e  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^d DUKE UNIVERSITY EYE CENTER   (United States)

^e NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Aqueous humour; Cell mechanics; Mechanobiology; Outflow resistance; Primary open angle glaucoma; Schlemm's canal

Indexed keywords

BODY FLUIDS; CELL CULTURE; ENDOTHELIAL CELLS; HYDRAULIC STRUCTURES; PHOSPHOLIPIDS; STIFFNESS; STRAIN; TRACTION (FRICTION);

AQUEOUS HUMOUR; CELL MECHANICS; MECHANO-BIOLOGY; OUTFLOW RESISTANCE; PRIMARY OPEN-ANGLE GLAUCOMA;

BIOMECHANICS;

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; BETA 2 ADRENERGIC RECEPTOR; ISOPRENALINE; LATRUNCULIN A; LYSOPHOSPHATIDIC ACID; SPHINGOSINE 1 PHOSPHATE; THROMBIN;

AQUEOUS HUMOR; ARTICLE; CYTOMETRY; ENDOTHELIUM CELL; FLOW KINETICS; FORCE; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROSCOPY; OPTICAL MAGNETIC TWISTING CYTOMETRY; PROTEIN EXPRESSION; SCHLEMM CANAL; TRACTION FORCE MICROSCOPY;

EID: 84863577692     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2011.0733     Document Type: Article

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