Latrunculin-A increases outflow facility in the monkey

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 5, 1999, Pages 931-941

  Peterson, Jennifer A ^a   Tian, Baohe ^a   Bershadsky, Alexander D ^b   Volberg, Tova ^b   Gangnon, Ronald E ^c   Spector, Ilan ^d   Geiger, Benjamin ^b   Kaufman, Paul L ^a,e  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d STONY BROOK UNIVERSITY   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGLAUCOMA AGENT; DIMETHYL SULFOXIDE; DRUG VEHICLE; EYE DROPS; G ACTIN; LATRUNCULIN A; MACROLIDE; UNCLASSIFIED DRUG; VINCULIN;

ACTIN FILAMENT; ANIMAL EXPERIMENT; ANTERIOR EYE CHAMBER; AQUEOUS HUMOR OUTFLOW; ARTICLE; CATTLE; CELL ADHESION; CELL LOSS; CONTROLLED STUDY; CYTOSKELETON; DOSE TIME EFFECT RELATION; DRUG EFFECT; ENDOTHELIUM CELL; INTRACAMERAL DRUG ADMINISTRATION; INTRAOCULAR PRESSURE; INTRAVENOUS DRUG ADMINISTRATION; MONKEY; NONHUMAN; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION; TRABECULAR MESHWORK;

ACTINS; ANIMALS; ANTERIOR CHAMBER; AQUEOUS HUMOR; BICYCLO COMPOUNDS, HETEROCYCLIC; CADHERINS; CATTLE; CELL ADHESION; CELL SIZE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; MACACA FASCICULARIS; MACACA MULATTA; MARINE TOXINS; OPHTHALMIC SOLUTIONS; PORIFERA; THIAZOLES; THIAZOLIDINES; TIME FACTORS; TRABECULAR MESHWORK; VINCULIN;

EID: 0032994540     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Birrell GB, Hedberg KK, Habliston DL, Griffith OH. Protein kinase C inhibitor H-7 alters the actin cytoskeleton of cultured cells. J Cell Physiol. 1989;141:74-84.
2. Volberg T, Geiger B, Citi S, Bershadsky AD. Effect of protein kinase inhibitor H-7 on the contractility, integrity, and membrane anchorage of the microfilament system. Cell Motil Cytoskeleton. 1994;29: 321-338.
3. Cooper JA. Effects of cytochalasins and phalloidin on actin. J Cell Biol. 1987;105:1473-1478.
4. Sampath P, Pollard TD. Effects of cytochalasin, phalloidin, and pH on the elongation of actin filaments. Biochemistry. 1991;30:1973-1980.
5. Polansky JR, Bloom E, Konami D, Weinreb RN, Alvarado JA. Cultured human trabecular cells: evaluation of hormonal and pharmacological responses in vitro. In: Ticho U, David R, eds. Recent Advances in Glaucoma. Amsterdam: Elsevier; 1984:201-206.
6. Perkins TW, Alvarado JA, Polansky JR, Stilwell L, Maglio M, Luster R. Trabecular meshwork cells grown on filters: conductivity and cytochalasin effects. Invest Ophthalmol Vis Sci. 1988;29:1836-1846.
7. Kaufman PL, Bárány EH. Cytochalasin B reversibly increases outflow facility in the eye of the cynomolgus monkey. Invest Ophthalmol Vis Sci. 1977;16:47-53.
8. Kaufman PL, Bill A, Bárány EH. Effect of cytochalasin B on conventional drainage of aqueous humor in the cynomolgus monkey. In: Bito LZ, Davson H, Fenstermacher JD, eds. The Ocular and Cerebrospinal Fluids. Exp Eye Res. 1977;25(suppl):411-414.
9. Kaufman PL, Erickson KA. Cytochalasin B and D dose-outflow facility response relationships in the cynomolgus monkey. Invest Ophthalmol Vis Sci. 1982;23:646-650.
10. Svedbergh B, Lütjen-Drecoll E, Ober M, Kaufman PL. Cytochalasin B-induced structural changes in the anterior ocular segment of the cynomolgus monkey. Invest Ophthalmol Vis Sci. 1978;17:718-734.
11. Johnstone M, Tanner D, Chau B, Kopecky K. Concentration-dependent morphologic effects of cytochalasin B in the aqueous outflow system. Invest Ophthalmol Vis Sci. 1980;19:835-841.
12. Coué M, Brenner SL, Spector I, Korn ED. Inhibition of actin polymerization by latrunculin A. FEBS Lett. 1987;213:316-318.
13. Spector I, Shochet NR, Blasberger D, Kashman Y. Latrunculinsnovel marine macrolides that disrupt microfilament organization and affect cell growth: comparison with cytochalasin D. Cell Motil Cytoskeleton. 1989;13:127-144.
14. Geiger B, Volberg T, Ginsberg D, Bitzur S, Sabanay I, Hynes RO. Broad spectrum pan-cadherin antibodies, reactive with the C-terminal 24 amino acid residues of N-cadherin. J Cell Sci. 1990;97: 607-614.
15. Bárány EH. Simultaneous measurement of changing intraocular pressure and outflow facility in the vervet monkey by constant pressure infusion. Invest Ophthalmol. 1964;3:135-143.
16. Erickson-Lamy KA, Kaufman PL, McDermott ML, France NK. Comparative anesthetic effects of aqueous humor dynamics in the cynomolgus monkey. Arch Ophthalmol. 1984;102:1815-1820.
17. Kaufman PL, Lütjen-Drecoll E. Total iridectomy in the primate in vivo: surgical technique and postoperative anatomy. Invest Ophthalmol. 1975;14:766-771.
18. Kaufman PL, Bárány EH. Loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey. Invest Ophthalmol. 1976;15:793-807.
19. 14-labeled atropine into the eye: a comparison of methods of application. Arch Ophthalmol. 1959;62:69-74.
20. Harris JE. Problems in drug penetration. In: Leopold IH, ed. Symposium on Ocular Therapy. St. Louis: CV Mosby: 1968;3:96-105.
21. Asseff CF, Weisman RL, Podos SM, Becker B. Ocular penetration of pilocarpine in primates. Am J Ophthalmol. 1973;75:212-215.
22. Snedecor GW, Cochran WG. Statistical Methods. 8th ed Ames, IA: Iowa State University Press; 1989:96-98.
23. SAS/STAT (R) User's Guide. Revision 6, 4th ed. Cary, NC: SAS Institute Inc.
24. SAS (R) Procedure's Guide. Revision 6, 3rd ed. Cary, NC: SAS Institute Inc.
25. Kiland JA, Peterson JA, Gabelt BT, Kaufman PL. Effect of DMSO and exchange volume on outflow resistance washout and response to pilocarpine during anterior chamber perfusion in monkeys. Curr Eye Res. 1997;16:1215-1220.
26. Jacob SW, Herschler R. Pharmacology of DMSO. Cryobiol. 1986; 23:14-27.
27. Peterson JA, Tian B, Geiger B, Kaufman PL. Latrunculin A causes mydriasis and cycloplegia in the cynomolgus monkey. Invest Ophthalmol Vis Sci. 1999;40:631-638.
28. Peterson JA, Tian B, Gabelt BT, Geiger G, Kaufman PL. Actin disrupting agents and their effects on anterior segment permeability in monkeys (XIII ICER Abstract). Exp Eye Res. 1998;67(suppl 1):S176.
29. Inomata H, Bill A, Smelser GK. Aqueous humor pathways through the trabecular meshwork and into Schlemm's canal in the cynomolgus monkey (Macaca irus): an electron microscopic study. Am J Ophthalmol. 1972;73:760-789.
30. Grierson I, Lee WR. Pressure-induced changes in the ultrastructure of the endothelium lining Schlemm's canal. Am J Ophthalmol. 1975;80:863-884.
31. Gipson IK, Anderson RA. Actin filaments in cells of human trabecular meshwork and Schlemm's canal. Invest Ophthalmol Vis Sci. 1979;18:547-561.
32. Epstein DL, Rohen JW. Morphology of the trabecular meshwork and inner-wall endothelium after catonized ferritin perfusion in the monkey eye. Invest Ophthalmol Vis Sci. 1991;32:160-171.
33. Tian B, Kaufman PL, Volberg T, Gabelt BT, Geiger B. H-7 disrupts the actin cytoskeleton and increases outflow facility. Arch Ophthalmol. 1998;116:633-643.
34. Croft MA, Hubbard WC, Kaufman PL. Effect of ethacrynic acid on aqueous outflow dynamics in monkeys. Invest Ophthalmol Vis Sci. 1994;35:1167-1175.
35. Croft MA, Kaufman PL. Effect of daily topical ethacrynic acid on aqueous humor dynamics in monkeys. Curr Eye Res. 1995;14:777-781.
36. Erickson-Lamy K, Schroeder A, Epstein DL. Ethacrynic acid induces reversible shape and cytoskeletal changes in cultured cells. Invest Ophthalmol Vis Sci. 1992;33:2631-2640.
37. Robinson JC, Kaufman PL. Cytochalasin B potentiates epinephrine's outflow facility increasing effect. Invest Ophthalmol Vis Sci. 1991;32:1614-1618.
38. Robinson JC, Kaufman PL. Phalloidin inhibits epinephrine's and cytochalsin B's facilitation of aqueous outflow. Arch Ophthalmol. 1994;112:1610-1613.
39. Tian B, Gabelt BT, Kaufman PL. Effect of staurosporine on outflow facility in monkeys. Invest Ophthalmol Vis Sci. 1999; 40:1009-1011.
40. Peterson JA, Tian B, Geiger B, Spector I, Kaufman PL. In cynomolgus monkeys latrunculin (LAT)-A, LAT-B increase outflow facility, LAT-A decreases intraocular pressure and initially increases aqueous humor formation [ARVO Abstract]. Invest Ophthalmol Vis Sci. 1997;38(4):S243. Abstract nr 1128.
41. Bill A, Lütjen-Drecoll E, Svedbergh B. Effects on intracameral Na2EDTA and EGTA on aqueous outflow routes in the monkey eye. Invest Ophthalmol Vis Sci. 1980;19:492-504.
42. Svedbergh B, Lütjen-Drecoll E, Ober M, Kaufman PL. Cytochalasin B-induced structural changes in the anterior ocular segment of the cynomolgus monkey. Invest Ophthalmol Vis Sci. 1978;17:718-734.