The effect of the H-1152P, a potent rho-associated coiled coil-formed protein kinase inhibitor, in rabbit normal and ocular hypertensive eyes

Current Eye Research

Volumn 34, Issue 4, 2009, Pages 282-286

  Nishio, Masahiro ^a   Fukunaga, Takaki ^b   Sugimoto, Masahiko ^b   Ikesugi, Kengo ^b   Sumi, Kengo ^a   Hidaka, Hiroyoshi ^a   Uji, Yukitaka ^b,c  

^a D Western Therapeutics Institute Inc   (Japan)

^b MIE UNIVERSITY   (Japan)

^c Department of Ophthalmology ^*  (Japan)

Author keywords

H 1152; H 1152P; Intraocular pressure; Ocular hypertension; Rabbit; ROCK

Indexed keywords

H 1152P; PHOSPHATE BUFFERED SALINE; PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG; 1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 2 METHYL 1 ((4 METHYL 5 ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; 2-METHYL-1-((4-METHYL-5-ISOQUINOLINYL)SULFONYL)HOMOPIPERAZINE; DRUG DERIVATIVE; RHO KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CONJUNCTIVA; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; EYE; INTRAOCULAR HYPERTENSION; INTRAOCULAR PRESSURE; NEW ZEALAND; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RABBIT; WATER LOADING; ANIMAL; DRUG ANTAGONISM; PATHOPHYSIOLOGY; TIME; TOPICAL DRUG ADMINISTRATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ADMINISTRATION, TOPICAL; ANIMALS; CONJUNCTIVA; DOSE-RESPONSE RELATIONSHIP, DRUG; INTRAOCULAR PRESSURE; OCULAR HYPERTENSION; PROTEIN KINASE INHIBITORS; RABBITS; RHO-ASSOCIATED KINASES; TIME FACTORS;

EID: 67649644686     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.1080/02713680902783763     Document Type: Article

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