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Volumn 298, Issue 3, 2010, Pages

Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells

Author keywords

Actomyosin; Extracellular signal regulated kinases; Fibronectin; Serum response factor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBRONECTIN; LAMININ; LYSOPHOSPHATIDIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MYOSIN ADENOSINE TRIPHOSPHATASE; MYOSIN LIGHT CHAIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; SERUM RESPONSE FACTOR; SHORT HAIRPIN RNA; TENASCIN; TRANSFORMING GROWTH FACTOR BETA2;

EID: 77749254700     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00317.2009     Document Type: Article
Times cited : (161)

References (65)
  • 1
    • 41049089213 scopus 로고    scopus 로고
    • Extracellular matrix in the trabecular meshwork
    • Acott TS, Kelley MJ. Extracellular matrix in the trabecular meshwork. Exp Eye Res 86: 543-561, 2008.
    • (2008) Exp Eye Res , vol.86 , pp. 543-561
    • Acott, T.S.1    Kelley, M.J.2
  • 3
    • 69149102112 scopus 로고    scopus 로고
    • Role of the actin cytoskeleton in tuning cellular responses to external mechanical stress
    • Asparuhova MB, Gelman L, Chiquet M. Role of the actin cytoskeleton in tuning cellular responses to external mechanical stress. Scand J Med Sci Sports 2009.
    • (2009) Scand J Med Sci Sports
    • Asparuhova, M.B.1    Gelman, L.2    Chiquet, M.3
  • 7
    • 0030994017 scopus 로고    scopus 로고
    • Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages
    • Choquet D, Felsenfeld DP, Sheetz MP. Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages. Cell 88: 39-48, 1997.
    • (1997) Cell , vol.88 , pp. 39-48
    • Choquet, D.1    Felsenfeld, D.P.2    Sheetz, M.P.3
  • 9
    • 0036088773 scopus 로고    scopus 로고
    • Inhibition of ERK attenuates force development by lowering myosin light chain phosphorylation
    • D'Angelo G, Adam LP. Inhibition of ERK attenuates force development by lowering myosin light chain phosphorylation. Am J Physiol Heart Circ Physiol 282: H602-H610, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • D'Angelo, G.1    Adam, L.P.2
  • 10
    • 0027165150 scopus 로고
    • The mitogen-activated protein kinase signal transduction pathway
    • Davis RJ. The mitogen-activated protein kinase signal transduction pathway. J Biol Chem 268: 14553-14556, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 14553-14556
    • Davis, R.J.1
  • 14
    • 0035150402 scopus 로고    scopus 로고
    • Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells
    • Fukata Y, Amano M, Kaibuchi K. Rho-Rho-kinase pathway in smooth muscle contraction and cytoskeletal reorganization of non-muscle cells. Trends Pharmacol Sci 22: 32-39, 2001.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 32-39
    • Fukata, Y.1    Amano, M.2    Kaibuchi, K.3
  • 15
    • 21744456373 scopus 로고    scopus 로고
    • Changes in aqueous humor dynamics with age and glaucoma
    • Gabelt BT, Kaufman PL. Changes in aqueous humor dynamics with age and glaucoma. Prog Retin Eye Res 24: 612-637, 2005.
    • (2005) Prog Retin Eye Res , vol.24 , pp. 612-637
    • Gabelt, B.T.1    Kaufman, P.L.2
  • 17
    • 57549110006 scopus 로고    scopus 로고
    • The role of cellular adaptation to mechanical forces in atherosclerosis
    • Hahn C, Schwartz MA. The role of cellular adaptation to mechanical forces in atherosclerosis. Arterioscler Thromb Vasc Biol 28: 2101-2107, 2008.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 2101-2107
    • Hahn, C.1    Schwartz, M.A.2
  • 18
    • 6944253469 scopus 로고    scopus 로고
    • The involvement of the rho-kinase pathway and its regulation in cytokine-induced collagen gel contraction by hyalocytes
    • Hirayama K, Hata Y, Noda Y, Miura M, Yamanaka I, Shimokawa H, Ishibashi T. The involvement of the rho-kinase pathway and its regulation in cytokine-induced collagen gel contraction by hyalocytes. Invest Ophthalmol Vis Sci 45: 3896-3903, 2004.
    • (2004) Invest Ophthalmol Vis Sci , vol.45 , pp. 3896-3903
    • Hirayama, K.1    Hata, Y.2    Noda, Y.3    Miura, M.4    Yamanaka, I.5    Shimokawa, H.6    Ishibashi, T.7
  • 20
    • 33744488545 scopus 로고    scopus 로고
    • Cellular mechanotransduction: Putting all the pieces together again
    • Ingber DE. Cellular mechanotransduction: putting all the pieces together again. FASEB J 20: 811-827, 2006.
    • (2006) FASEB J , vol.20 , pp. 811-827
    • Ingber, D.E.1
  • 21
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: Biochemistry and biology
    • Jaffe AB, Hall A. Rho GTPases: biochemistry and biology. Annu Rev Cell Dev Biol 21: 247-269, 2005.
    • (2005) Annu Rev Cell Dev Biol , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 22
    • 4644363543 scopus 로고    scopus 로고
    • The aqueous outflow system as a mechanical pump: Evidence from examination of tissue and aqueous movement in human and non-human primates
    • Johnstone MA. The aqueous outflow system as a mechanical pump: evidence from examination of tissue and aqueous movement in human and non-human primates. J Glaucoma 13: 421-438, 2004.
    • (2004) J Glaucoma , vol.13 , pp. 421-438
    • Johnstone, M.A.1
  • 23
    • 27644497978 scopus 로고    scopus 로고
    • Cooperative effects of Rho and mechanical stretch on stress fiber organization
    • Kaunas R, Nguyen P, Usami S, Chien S. Cooperative effects of Rho and mechanical stretch on stress fiber organization. Proc Natl Acad Sci USA 102: 15895-15900, 2005.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15895-15900
    • Kaunas, R.1    Nguyen, P.2    Usami, S.3    Chien, S.4
  • 26
    • 16244382549 scopus 로고    scopus 로고
    • Muscle-specific signaling mechanism that links actin dynamics to serum response factor
    • Kuwahara K, Barrientos T, Pipes GC, Li S, Olson EN. Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Mol Cell Biol 25: 3173-3181, 2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 3173-3181
    • Kuwahara, K.1    Barrientos, T.2    Pipes, G.C.3    Li, S.4    Olson, E.N.5
  • 27
    • 20544468453 scopus 로고    scopus 로고
    • Morphological changes in glaucomatous eyes and the role of TGFβ2 for the pathogenesis of the disease
    • Lutjen-Drecoll E. Morphological changes in glaucomatous eyes and the role of TGFβ2 for the pathogenesis of the disease. Exp Eye Res 81: 1-4, 2005.
    • (2005) Exp Eye Res , vol.81 , pp. 1-4
    • Lutjen-Drecoll, E.1
  • 28
    • 0019489839 scopus 로고
    • Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyes
    • Lutjen-Drecoll E, Futa R, Rohen JW. Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyes. Invest Ophthalmol Vis Sci 21: 563-573, 1981.
    • (1981) Invest Ophthalmol Vis Sci , vol.21 , pp. 563-573
    • Lutjen-Drecoll, E.1    Futa, R.2    Rohen, J.W.3
  • 29
    • 31044448209 scopus 로고    scopus 로고
    • What controls aqueous humour outflow resistance?
    • Johnson M. What controls aqueous humour outflow resistance? Exp Eye Res 82: 545-557, 2006.
    • (2006) Exp Eye Res , vol.82 , pp. 545-557
    • Johnson, M.1
  • 30
    • 0035808389 scopus 로고    scopus 로고
    • Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization
    • Mack CP, Somlyo AV, Hautmann M, Somlyo AP, Owens GK. Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. J Biol Chem 276: 341-347, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 341-347
    • Mack, C.P.1    Somlyo, A.V.2    Hautmann, M.3    Somlyo, A.P.4    Owens, G.K.5
  • 31
    • 2442649165 scopus 로고    scopus 로고
    • Enhanced tenascin-C expression and matrix deposition during Ras/TGF-β-induced progression of mammary tumor cells
    • Maschler S, Grunert S, Danielopol A, Beug H, Wirl G. Enhanced tenascin-C expression and matrix deposition during Ras/TGF-β-induced progression of mammary tumor cells. Oncogene 23: 3622-3633, 2004.
    • (2004) Oncogene , vol.23 , pp. 3622-3633
    • Maschler, S.1    Grunert, S.2    Danielopol, A.3    Beug, H.4    Wirl, G.5
  • 32
    • 61849140657 scopus 로고    scopus 로고
    • Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis
    • Medjkane S, Perez-Sanchez C, Gaggioli C, Sahai E, Treisman R. Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis. Nat Cell Biol 11: 257-268, 2009.
    • (2009) Nat Cell Biol , vol.11 , pp. 257-268
    • Medjkane, S.1    Perez-Sanchez, C.2    Gaggioli, C.3    Sahai, E.4    Treisman, R.5
  • 34
    • 33846301667 scopus 로고    scopus 로고
    • Serum response factor: Master regulator of the actin cytoskeleton and contractile apparatus
    • Miano JM, Long X, Fujiwara K. Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus. Am J Physiol Cell Physiol 292: C70-C81, 2007.
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Miano, J.M.1    Long, X.2    Fujiwara, K.3
  • 35
    • 0038737042 scopus 로고    scopus 로고
    • Actin dynamics control SRF activity by regulation of its coactivator MAL
    • Miralles F, Posern G, Zaromytidou AI, Treisman R. Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell 113: 329-342, 2003.
    • (2003) Cell , vol.113 , pp. 329-342
    • Miralles, F.1    Posern, G.2    Zaromytidou, A.I.3    Treisman, R.4
  • 37
    • 0036845687 scopus 로고    scopus 로고
    • Signaling mechanism of TGF-β1-induced collagen contraction mediated by bovine trabecular meshwork cells
    • Nakamura Y, Hirano S, Suzuki K, Seki K, Sagara T, Nishida T. Signaling mechanism of TGF-β1-induced collagen contraction mediated by bovine trabecular meshwork cells. Invest Ophthalmol Vis Sci 43: 3465-3472, 2002.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3465-3472
    • Nakamura, Y.1    Hirano, S.2    Suzuki, K.3    Seki, K.4    Sagara, T.5    Nishida, T.6
  • 39
    • 12744252830 scopus 로고    scopus 로고
    • Regulation of myosin light chain phosphorylation in the trabecular meshwork: Role in aqueous humour outflow facility
    • Rao PV, Deng P, Sasaki Y, Epstein DL. Regulation of myosin light chain phosphorylation in the trabecular meshwork: role in aqueous humour outflow facility. Exp Eye Res 80: 197-206, 2005.
    • (2005) Exp Eye Res , vol.80 , pp. 197-206
    • Rao, P.V.1    Deng, P.2    Sasaki, Y.3    Epstein, D.L.4
  • 40
    • 0035066006 scopus 로고    scopus 로고
    • Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632
    • Rao PV, Deng PF, Kumar J, Epstein DL. Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. Invest Ophthalmol Vis Sci 42: 1029-1037, 2001.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 1029-1037
    • Rao, P.V.1    Deng, P.F.2    Kumar, J.3    Epstein, D.L.4
  • 41
    • 34249694646 scopus 로고    scopus 로고
    • Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma
    • Rao VP, Epstein DL. Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. BioDrugs 21: 167-177, 2007.
    • (2007) BioDrugs , vol.21 , pp. 167-177
    • Rao, V.P.1    Epstein, D.L.2
  • 42
    • 22744448697 scopus 로고    scopus 로고
    • Mechanical signals regulating extracellular matrix gene expression in fibroblasts
    • Sarasa-Renedo A, Chiquet M. Mechanical signals regulating extracellular matrix gene expression in fibroblasts. Scand J Med Sci Sports 15: 223-230, 2005.
    • (2005) Scand J Med Sci Sports , vol.15 , pp. 223-230
    • Sarasa-Renedo, A.1    Chiquet, M.2
  • 43
    • 33646058254 scopus 로고    scopus 로고
    • Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain
    • Sarasa-Renedo A, Tunc-Civelek V, Chiquet M. Role of RhoA/ROCK-dependent actin contractility in the induction of tenascin-C by cyclic tensile strain. Exp Cell Res 312: 1361-1370, 2006.
    • (2006) Exp Cell Res , vol.312 , pp. 1361-1370
    • Sarasa-Renedo, A.1    Tunc-Civelek, V.2    Chiquet, M.3
  • 44
    • 7944230118 scopus 로고    scopus 로고
    • Lysophosphatidic acid inhibits TGF-β-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts
    • Sato M, Shegogue D, Hatamochi A, Yamazaki S, Trojanowska M. Lysophosphatidic acid inhibits TGF-β-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts. Matrix Biol 23: 353-361, 2004.
    • (2004) Matrix Biol , vol.23 , pp. 353-361
    • Sato, M.1    Shegogue, D.2    Hatamochi, A.3    Yamazaki, S.4    Trojanowska, M.5
  • 45
    • 39549084168 scopus 로고    scopus 로고
    • Substrate rigidity modulates cell matrix interactions and protein expression in human trabecular meshwork cells
    • Schlunck G, Han H, Wecker T, Kampik D, Meyer-ter-Vehn T, Grehn F. Substrate rigidity modulates cell matrix interactions and protein expression in human trabecular meshwork cells. Invest Ophthalmol Vis Sci 49: 262-269, 2008.
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 262-269
    • Schlunck, G.1    Han, H.2    Wecker, T.3    Kampik, D.4    Meyer-ter-Vehn, T.5    Grehn, F.6
  • 46
    • 13544264582 scopus 로고    scopus 로고
    • Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells
    • Shikata Y, Rios A, Kawkitinarong K, DePaola N, Garcia JG, Birukov KG. Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells. Exp Cell Res 304: 40-49, 2005.
    • (2005) Exp Cell Res , vol.304 , pp. 40-49
    • Shikata, Y.1    Rios, A.2    Kawkitinarong, K.3    DePaola, N.4    Garcia, J.G.5    Birukov, K.G.6
  • 47
    • 0141751697 scopus 로고    scopus 로고
    • 2+ sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
    • 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83: 1325-1358, 2003.
    • (2003) Physiol Rev , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 48
    • 64249131959 scopus 로고    scopus 로고
    • The trabecular meshwork outflow pathways: Structural and functional aspects
    • Tamm ER. The trabecular meshwork outflow pathways: structural and functional aspects. Exp Eye Res 88: 648-655, 2009.
    • (2009) Exp Eye Res , vol.88 , pp. 648-655
    • Tamm, E.R.1
  • 49
    • 35848942149 scopus 로고    scopus 로고
    • What increases outflow resistance in primary open-angle glaucoma?
    • Tamm ER, Fuchshofer R. What increases outflow resistance in primary open-angle glaucoma? Surv Ophthalmol 52, Suppl 2: S101-S104, 2007.
    • (2007) Surv Ophthalmol , vol.52 , Issue.SUPPL. 2
    • Tamm, E.R.1    Fuchshofer, R.2
  • 50
    • 71749116071 scopus 로고    scopus 로고
    • Phosphorylation of myocardin by extracellular signal regulated protein kinase
    • Taurin S, Sandbo N, Yau DM, Sethakorn N, Kach J, Dulin NO. Phosphorylation of myocardin by extracellular signal regulated protein kinase. J Biol Chem 284: 33789-33794, 2009.
    • (2009) J Biol Chem , vol.284 , pp. 33789-33794
    • Taurin, S.1    Sandbo, N.2    Yau, D.M.3    Sethakorn, N.4    Kach, J.5    Dulin, N.O.6
  • 51
    • 64249129112 scopus 로고    scopus 로고
    • The role of the actomyosin system in regulating trabecular fluid outflow
    • Tian B, Gabelt BT, Geiger B, Kaufman PL. The role of the actomyosin system in regulating trabecular fluid outflow. Exp Eye Res 88: 713-717, 2009.
    • (2009) Exp Eye Res , vol.88 , pp. 713-717
    • Tian, B.1    Gabelt, B.T.2    Geiger, B.3    Kaufman, P.L.4
  • 52
    • 33644866797 scopus 로고    scopus 로고
    • Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response
    • Tzima E. Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response. Circ Res 98: 176-185, 2006.
    • (2006) Circ Res , vol.98 , pp. 176-185
    • Tzima, E.1
  • 53
    • 33645773666 scopus 로고    scopus 로고
    • Local force and geometry sensing regulate cell functions
    • Vogel V, Sheetz M. Local force and geometry sensing regulate cell functions. Nat Rev Mol Cell Biol 7: 265-275, 2006.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 265-275
    • Vogel, V.1    Sheetz, M.2
  • 54
    • 5444235587 scopus 로고    scopus 로고
    • Control of smooth muscle development by the myocardin family of transcriptional coactivators
    • Wang DZ, Olson EN. Control of smooth muscle development by the myocardin family of transcriptional coactivators. Curr Opin Genet Dev 14: 558-566, 2004.
    • (2004) Curr Opin Genet Dev , vol.14 , pp. 558-566
    • Wang, D.Z.1    Olson, E.N.2
  • 55
    • 29144478386 scopus 로고    scopus 로고
    • Multiple roles of α-smooth muscle actin in mechanotransduction
    • Wang J, Zohar R, McCulloch CA. Multiple roles of α-smooth muscle actin in mechanotransduction. Exp Cell Res 312: 205-214, 2006.
    • (2006) Exp Cell Res , vol.312 , pp. 205-214
    • Wang, J.1    Zohar, R.2    McCulloch, C.A.3
  • 56
    • 2442643730 scopus 로고    scopus 로고
    • Primary open-angle glaucoma
    • Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet 363: 1711-1720, 2004.
    • (2004) Lancet , vol.363 , pp. 1711-1720
    • Weinreb, R.N.1    Khaw, P.T.2
  • 57
    • 0029046597 scopus 로고
    • Regulation of outflow rate and resistance in the perfused anterior segment of the bovine eye
    • Wiederholt M, Bielka S, Schweig F, Lutjen-Drecoll E, Lepple-Wienhues A. Regulation of outflow rate and resistance in the perfused anterior segment of the bovine eye. Exp Eye Res 61: 223-234, 1995.
    • (1995) Exp Eye Res , vol.61 , pp. 223-234
    • Wiederholt, M.1    Bielka, S.2    Schweig, F.3    Lutjen-Drecoll, E.4    Lepple-Wienhues, A.5
  • 58
    • 0034002380 scopus 로고    scopus 로고
    • The regulation of trabecular meshwork and ciliary muscle contractility
    • Wiederholt M, Thieme H, Stumpff F. The regulation of trabecular meshwork and ciliary muscle contractility. Prog Retin Eye Res 19: 271-295, 2000.
    • (2000) Prog Retin Eye Res , vol.19 , pp. 271-295
    • Wiederholt, M.1    Thieme, H.2    Stumpff, F.3
  • 59
    • 27644435720 scopus 로고    scopus 로고
    • RAS and TGF-β exert antagonistic effects on extracellular matrix gene expression and fibroblast transformation
    • Wisdom R, Huynh L, Hsia D, Kim S. RAS and TGF-β exert antagonistic effects on extracellular matrix gene expression and fibroblast transformation. Oncogene 24: 7043-7054, 2005.
    • (2005) Oncogene , vol.24 , pp. 7043-7054
    • Wisdom, R.1    Huynh, L.2    Hsia, D.3    Kim, S.4
  • 60
    • 64249118693 scopus 로고    scopus 로고
    • Mechanobiology of trabecular meshwork cells
    • WuDunn D. Mechanobiology of trabecular meshwork cells. Exp Eye Res 88: 718-723, 2009.
    • (2009) Exp Eye Res , vol.88 , pp. 718-723
    • WuDunn, D.1
  • 61
    • 0036086110 scopus 로고    scopus 로고
    • ERK MAP kinases regulate smooth muscle contraction in ovine uterine artery: Effect of pregnancy
    • Xiao D, Zhang L. ERK MAP kinases regulate smooth muscle contraction in ovine uterine artery: effect of pregnancy. Am J Physiol Heart Circ Physiol 282: H292-H300, 2002.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Xiao, D.1    Zhang, L.2
  • 62
    • 0029980533 scopus 로고    scopus 로고
    • The extracellular matrix and its modulation in the trabecular meshwork
    • Yue BY. The extracellular matrix and its modulation in the trabecular meshwork. Surv Ophthalmol 40: 379-390, 1996.
    • (1996) Surv Ophthalmol , vol.40 , pp. 379-390
    • Yue, B.Y.1
  • 63
    • 57349186040 scopus 로고    scopus 로고
    • Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork
    • Zhang M, Maddala R, Rao PV. Novel molecular insights into RhoA GTPase-induced resistance to aqueous humor outflow through the trabecular meshwork. Am J Physiol Cell Physiol 295: C1057-C1070, 2008.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Zhang, M.1    Maddala, R.2    Rao, P.V.3
  • 64
    • 33644679414 scopus 로고    scopus 로고
    • Zhang M, Rao PV. Blebbistatin, a novel inhibitor of myosin II ATPase activity, increases aqueous humor outflow facility in perfused enucleated porcine eyes. Invest Ophthalmol Vis Sci 46: 4130-4138, 2005.
    • Zhang M, Rao PV. Blebbistatin, a novel inhibitor of myosin II ATPase activity, increases aqueous humor outflow facility in perfused enucleated porcine eyes. Invest Ophthalmol Vis Sci 46: 4130-4138, 2005.
  • 65
    • 0032550177 scopus 로고    scopus 로고
    • Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly
    • Zhong C, Chrzanowska-Wodnicka M, Brown J, Shaub A, Belkin AM, Burridge K. Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly. J Cell Biol 141: 539-551, 1998.
    • (1998) J Cell Biol , vol.141 , pp. 539-551
    • Zhong, C.1    Chrzanowska-Wodnicka, M.2    Brown, J.3    Shaub, A.4    Belkin, A.M.5    Burridge, K.6


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