-
1
-
-
2442643730
-
Primary open-angle glaucoma
-
DOI 10.1016/S0140-6736(04)16257-0, PII S0140673604162570
-
Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet 2004;363:1711-1720. (Pubitemid 38670330)
-
(2004)
Lancet
, vol.363
, Issue.9422
, pp. 1711-1720
-
-
Weinreb, R.N.1
Tee Khaw, P.2
-
2
-
-
0028038213
-
Mechanisms of optic nerve damage in primary open angle glaucoma
-
DOI 10.1016/S0039-6257(05)80042-6
-
Fechtner RD, Weinreb RN. Mechanisms of optic nerve damage in primary open angle glaucoma. Surv Ophthalmol 1994;39:23-42. (Pubitemid 24243493)
-
(1994)
Survey of Ophthalmology
, vol.39
, Issue.1
, pp. 23-42
-
-
Fechtner, R.D.1
Weinreb, R.N.2
-
3
-
-
0028433377
-
The vascular concept of glaucoma
-
DOI 10.1016/0039-6257(94)90041-8
-
Flammer J. The vascular concept of glaucoma. Surv Ophthalmol 1994;38 Suppl:S3-S6. (Pubitemid 124017796)
-
(1994)
Survey of Ophthalmology
, vol.38
, Issue.SUPPL. 1
-
-
Flammer, J.1
-
5
-
-
0027973532
-
Factors contributing to the progression of visual field damage in eyes with normal-tension glaucoma
-
Araie M, Sekine M, Suzuki Y, Koseki N. Factors contributing to the progression of visual field damage in eyes with normal-tension glaucoma. Ophthalmology 1994;101:1440-1444. (Pubitemid 24319293)
-
(1994)
Ophthalmology
, vol.101
, Issue.8
, pp. 1440-1444
-
-
Araie, M.1
Sekine, M.2
Suzuki, Y.3
Koseki, N.4
-
6
-
-
0029791373
-
The small GTPase Rho: Cellular functions and signal transduction
-
Narumiya S. The small GTPase Rho: cellular functions and signal transduction. J Biochem 1996;120:215-228. (Pubitemid 26335910)
-
(1996)
Journal of Biochemistry
, vol.120
, Issue.2
, pp. 215-228
-
-
Narumiya, S.1
-
7
-
-
0030612748
-
Rho effecters and reorganization of actin cytoskeleton
-
DOI 10.1016/S0014-5793(97)00317-7, PII S0014579397003177
-
Narumiya S, Ishizaki T, Watanabe N. Rho effectors and reorganization of actin cytoskeleton. FEBS Lett 1997;410: 68-72. (Pubitemid 27283386)
-
(1997)
FEBS Letters
, vol.410
, Issue.1
, pp. 68-72
-
-
Narumiya, S.1
Ishizaki, T.2
Watanabe, N.3
-
8
-
-
0025195876
-
Microinjection of recombinant p21rho induces rapid changes in cell morphology
-
Paterson HF, Self AJ, Garrett MD, Just I, Aktories K, Hall A. Microinjection of recombinant p21rho induces rapid changes in cell morphology. J Cell Biol 1990;111:1001-1007.
-
(1990)
J. Cell Biol.
, vol.111
, pp. 1001-1007
-
-
Paterson, H.F.1
Self, A.J.2
Garrett, M.D.3
Just, I.4
Aktories, K.5
Hall, A.6
-
9
-
-
0027952703
-
Involvement of Rho p21 small GTP-binding protein and its regulator in the HGF-induced cell motility
-
Takaishi K, Sasaki T, Kato M et al. Involvement of Rho p21 small GTP-binding protein and its regulator in the HGFinduced cell motility. Oncogene 1994;9:273-279. (Pubitemid 24020959)
-
(1994)
Oncogene
, vol.9
, Issue.1
, pp. 273-279
-
-
Takaishi, K.1
Sasaki, T.2
Kato, M.3
Yamochi, W.4
Kuroda, S.5
Nakamura, T.6
Takeichi, M.7
Takai, Y.8
-
10
-
-
0027509362
-
Regulation of cytoplasmic division of Xenopus embryo by Rho p21 and its inhibitory GDP/GTP exchange protein Rho GDI
-
Kishi K, Sasaki T, Kuroda S, Itoh T, Takai Y. Regulation of cytoplasmic division of Xenopus embryo by Rho p21 and its inhibitory GDP/GTP exchange protein (Rho GDI).J Cell Biol 1993;120:1187-1195.
-
(1993)
J. Cell Biol.
, vol.120
, pp. 1187-1195
-
-
Kishi, K.1
Sasaki, T.2
Kuroda, S.3
Itoh, T.4
Takai, Y.5
-
11
-
-
0026806476
-
Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction
-
Hirata K, Kikuchi A, Sasaki T et al. Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem 1992;267:8719-8722.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 8719-8722
-
-
Hirata, K.1
Kikuchi, A.2
Sasaki, T.3
-
12
-
-
0030071903
-
Role of guanine nucleotide- binding proteins-ras-family or trimeric proteins or both-in Ca2+ sensitization of smooth muscle
-
USA
-
Gong MC, Iizuka K, Nixon G et al. Role of guanine nucleotide- binding proteins-ras-family or trimeric proteins or both-in Ca2+ sensitization of smooth muscle. Proc Natl Acad Sci USA 1996;93:1340-1345.
-
(1996)
Proc. Natl. Acad. Sci.
, vol.93
, pp. 1340-1345
-
-
Gong, M.C.1
Iizuka, K.2
Nixon, G.3
-
13
-
-
9244220646
-
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
-
Ishizaki T, Maekawa M, Fujisawa K et al. The small GTPbinding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J 1996;15:1885-1893. (Pubitemid 26119224)
-
(1996)
EMBO Journal
, vol.15
, Issue.8
, pp. 1885-1893
-
-
Ishizaki, T.1
Maekawa, M.2
Fujisawa, K.3
Okawa, K.4
Iwamatsu, A.5
Fujita, A.6
Watanabe, N.7
Saito, Y.8
Kakizuka, A.9
Morii, N.10
Narumiya, S.11
-
15
-
-
0026074852
-
Morphology of the trabecular meshwork and inner-wall endothelium after cationized ferritin perfusion in the monkey eye
-
Epstein DL, Rohen JW. Morphology of the trabecular meshwork and inner-wall endothelium after cationized ferritin perfusion in the monkey eye. Invest Ophthalmol Vis Sci 1991;32:160-171.
-
(1991)
Invest. Ophthalmol. Vis. Sci.
, vol.32
, pp. 160-171
-
-
Epstein, D.L.1
Rohen, J.W.2
-
16
-
-
0034066511
-
Cytoskeletal involvement in the regulation of aqueous humor outflow
-
Tian B, Geiger B, Epstein DL, Kaufman PL. Cytoskeletal involvement in the regulation of aqueous humor outflow. Invest Ophthalmol Vis Sci 2000;41:619-623. (Pubitemid 30158867)
-
(2000)
Investigative Ophthalmology and Visual Science
, vol.41
, Issue.3
, pp. 619-623
-
-
Tian, B.1
Geiger, B.2
Epstein, D.L.3
Kaufman, P.L.4
-
17
-
-
0030656619
-
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
-
DOI 10.1038/40187
-
Uehata M, Ishizaki T, Satoh H et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 1997;389:990-994. (Pubitemid 27485693)
-
(1997)
Nature
, vol.389
, Issue.6654
, pp. 990-994
-
-
Uehata, M.1
Ishizaki, T.2
Satoh, H.3
Ono, T.4
Kawahara, T.5
Morishita, T.6
Tamakawa, H.7
Yamagami, K.8
Inui, J.9
Maekawa, M.10
Narumiya, S.11
-
18
-
-
0035164065
-
Effects of Rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility
-
Honjo M, Tanihara H, Inatani M et al. Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Invest Ophthalmol Vis Sci 2001;42:137-144. (Pubitemid 32059420)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.1
, pp. 137-144
-
-
Honjo, M.1
Tanihara, H.2
Inatani, M.3
Kido, N.4
Sawamura, T.5
Yue, B.Y.J.T.6
Narumiya, S.7
Honda, Y.8
-
19
-
-
0035726683
-
Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase
-
DOI 10.1076/ceyr.22.6.470.5489
-
Waki M, Yoshida Y, Oka T, Azuma M. Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase. Curr Eye Res 2001;22:470-474. (Pubitemid 34253206)
-
(2001)
Current Eye Research
, vol.22
, Issue.6
, pp. 470-474
-
-
Waki, M.1
Yoshida, Y.2
Oka, T.3
Azuma, M.4
-
20
-
-
0035066006
-
Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632
-
Rao PV, Deng PF, Kumar J, Epstein DL. Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. Invest Ophthalmol Vis Sci 2001;42: 1029-1037. (Pubitemid 32289800)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.5
, pp. 1029-1037
-
-
Vasantha Rao, P.1
Deng, P.-F.2
Kumar, J.3
Epstein, D.L.4
-
21
-
-
34548073671
-
Effects of topical administration of Y-39983, a selective Rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys
-
DOI 10.1167/iovs.05-1617
-
Tokushige H, Inatani M, Nemoto S et al. Effects of topical administration of Y-39983, a selective Rho-associated protein kinase inhibitor, on ocular tissues in rabbits and monkeys. Invest Ophthalmol Vis Sci 2007;48:3216-3222. (Pubitemid 351261166)
-
(2007)
Investigative Ophthalmology and Visual Science
, vol.48
, Issue.7
, pp. 3216-3222
-
-
Tokushige, H.1
Inatani, M.2
Nemoto, S.3
Sakaki, H.4
Katayama, K.5
Uehata, M.6
Tanihara, H.7
-
22
-
-
40849130917
-
Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers
-
DOI 10.1001/archophthalmol.2007.76
-
Tanihara H, Inatani M, Honjo M, Tokushige H, Azuma J, Araie M. Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers. Arch Ophthalmol 2008;126:309-315. (Pubitemid 351398453)
-
(2008)
Archives of Ophthalmology
, vol.126
, Issue.3
, pp. 309-315
-
-
Tanihara, H.1
Inatani, M.2
Honjo, M.3
Tokushige, H.4
Azuma, J.5
Araie, M.6
-
23
-
-
14444288533
-
Molecular dissection of the Rho-associated protein kinase (p160ROCK)- regulated neurite remodeling in neuroblastoma N1E-115 cells
-
DOI 10.1083/jcb.141.7.1625
-
Hirose M, Ishizaki T, Watanabe N et al. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling in neuroblastoma N1E-115 cells. J Cell Biol 1998;141:1625-1636. (Pubitemid 28309176)
-
(1998)
Journal of Cell Biology
, vol.141
, Issue.7
, pp. 1625-1636
-
-
Hirose, M.1
Ishizaki, T.2
Watanabe, N.3
Uehata, M.4
Kranenburg, O.5
Moolenaar, W.H.6
Matsumura, F.7
Maekawa, M.8
Bito, H.9
Narumiya, S.10
-
24
-
-
0027250451
-
An application of laser speckle phenomenon for noninvasive two-dimensional evaluation of microcirculation in ocular fundus a preliminary report
-
Tamaki Y, Kawamoto E, Araie M, Eguchi S, Fujii H. An application of laser speckle phenomenon for noninvasive twodimensional evaluation of microcirculation in ocular fundus-a preliminary report. Jpn J Ophthalmol 1993;37:178-186. (Pubitemid 23230300)
-
(1993)
Japanese Journal of Ophthalmology
, vol.37
, Issue.2
, pp. 178-186
-
-
Tamaki, Y.1
Kawamoto, E.2
Araie, M.3
Eguchi, S.4
Fujii, H.5
-
25
-
-
0028951869
-
Non-contact two-dimensional measurement of tissue circulation in choroid and optic nerve head using laser speckle phenomenon
-
Tamaki Y, Araie M, Kawamoto E, Eguchi S, Fujii H. Non-contact, two-dimensional measurement of tissue circulation in choroid and optic nerve head using laser speckle phenomenon. Exp Eye Res 1995;60:373-383.
-
(1995)
Exp. Eye Res.
, vol.60
, pp. 373-383
-
-
Tamaki, Y.1
Araie, M.2
Kawamoto, E.3
Eguchi, S.4
Fujii, H.5
-
26
-
-
0024109174
-
Immunological morphological and electrophysiological variation among retinal ganglion cells purified by panning
-
Barres BA, Silverstein BE, Corey DP, Chun LL. Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning. Neuron 1988;1:791-803.
-
(1988)
Neuron
, vol.1
, pp. 791-803
-
-
Barres, B.A.1
Silverstein, B.E.2
Corey, D.P.3
Chun, L.L.4
-
28
-
-
17744397579
-
Contribution of ROCK in contraction of trabecular meshwork: Proposed mechanism for regulating aqueous outflow in monkey and human eyes
-
DOI 10.1002/jps.20285
-
Nakajima E, Nakajima T, Minagawa Y, Shearer TR, Azuma M. Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes. J Pharm Sci 2005;94:701-708. (Pubitemid 40577304)
-
(2005)
Journal of Pharmaceutical Sciences
, vol.94
, Issue.4
, pp. 701-708
-
-
Nakajima, E.1
Nakajima, T.2
Minagawa, Y.3
Shearer, T.R.4
Azuma, M.5
-
29
-
-
0032822666
-
Survival of axotomized retinal ganglion cells in peripheral nerve- grafted ferrets
-
Quan MZ, Kosaka J, Watanabe M, Wakabayashi T, Fukuda Y. Survival of axotomized retinal ganglion cells in peripheral nerve-grafted ferrets. Invest Ophthalmol Vis Sci 1999;40:2360-2366. (Pubitemid 29418392)
-
(1999)
Investigative Ophthalmology and Visual Science
, vol.40
, Issue.10
, pp. 2360-2366
-
-
Quan, M.-Z.1
Kosaka, J.2
Watanabe, M.3
Wakabayashi, T.4
Fukuda, Y.5
-
30
-
-
0036785777
-
Topical nipradilol: Effects on optic nerve head circulation in humans and periocular distribution in monkeys
-
Mizuno K, Koide T, Saito N et al. Topical nipradilol: effects on optic nerve head circulation in humans and periocular distribution in monkeys. Invest Ophthalmol Vis Sci 2002;43:3243-3250.
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 3243-3250
-
-
Mizuno, K.1
Koide, T.2
Saito, N.3
-
31
-
-
66849127757
-
Route of penetration of topically instilled nipradilol into the ipsilateral posterior retina
-
Mizuno K, Koide T, Shimada S, Mori J, Sawanobori K, Araie M. Route of penetration of topically instilled nipradilol into the ipsilateral posterior retina. Invest Ophthalmol Vis Sci 2009;50:2839-2847.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 2839-2847
-
-
Mizuno, K.1
Koide, T.2
Shimada, S.3
Mori, J.4
Sawanobori, K.5
Araie, M.6
-
32
-
-
18244383304
-
Time course of changes in optic nerve head circulation after acute reduction in intraocular pressure
-
DOI 10.1167/iovs.04-1082
-
Takayama J, Tomidokoro A, Tamaki Y, Araie M. Time course of changes in optic nerve head circulation after acute reduction in intraocular pressure. Invest Ophthalmol Vis Sci 2005;46:1409-1419. (Pubitemid 41685883)
-
(2005)
Investigative Ophthalmology and Visual Science
, vol.46
, Issue.4
, pp. 1409-1419
-
-
Takayama, J.1
Tomidokoro, A.2
Tamaki, Y.3
Araie, M.4
-
33
-
-
0034809474
-
A hypothesis to explain ganglion cell death caused by vascular insults at the optic nerve head: Possible implication for the treatment of glaucoma
-
DOI 10.1136/bjo.85.10.1252
-
Osborne NN, Melena J, Chidlow G, Wood JP. A hypothesis to explain ganglion cell death caused by vascular insults at the optic nerve head: possible implication for the treatment of glaucoma. Br J Ophthalmol 2001;85:1252-1259. (Pubitemid 32929554)
-
(2001)
British Journal of Ophthalmology
, vol.85
, Issue.10
, pp. 1252-1259
-
-
Osborne, N.N.1
Melena, J.2
Chidlow, G.3
Wood, J.P.M.4
-
34
-
-
0032787582
-
Neuroprotection in relation to retinal ischemia and relevance to glaucoma
-
DOI 10.1016/S0039-6257(99)00044-2, PII S0039625799000442
-
Osborne NN, Ugarte M, Chao M et al. Neuroprotection in relation to retinal ischemia and relevance to glaucoma. Surv Ophthalmol 1999;43 Suppl 1:S102-S128. (Pubitemid 29328586)
-
(1999)
Survey of Ophthalmology
, vol.43
, Issue.6 SUPPL.
-
-
Osborne, N.N.1
Ugarte, M.2
Chao, M.3
Chidlow, G.4
Bae, J.H.5
Wood, J.P.M.6
Nash, M.S.7
-
35
-
-
79952230532
-
Effects of fasudil a Rho-associated protein kinase inhibitor on optic nerve head blood flow in rabbits
-
Sugiyama T, Shibata M, Kajiura S et al. Effects of fasudil, a Rho-associated protein kinase inhibitor, on optic nerve head blood flow in rabbits. Invest Ophthalmol Vis Sci 2011;52:64-69.
-
(2011)
Invest. Ophthalmol. Vis. Sci.
, vol.52
, pp. 64-69
-
-
Sugiyama, T.1
Shibata, M.2
Kajiura, S.3
-
36
-
-
34249694646
-
Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma
-
DOI 10.2165/00063030-200721030-00004
-
Rao VP, Epstein DL. Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. BioDrugs 2007;21:167-177. (Pubitemid 46827850)
-
(2007)
BioDrugs
, vol.21
, Issue.3
, pp. 167-177
-
-
Rao, V.P.1
Epstein, D.L.2
-
37
-
-
0037408391
-
The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI
-
Yamashita T, Tohyama M. The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci 2003;6:461-467. (Pubitemid 36514693)
-
(2003)
Nature Neuroscience
, vol.6
, Issue.5
, pp. 461-467
-
-
Yamashita, T.1
Tohyama, M.2
-
38
-
-
2442693021
-
Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: Expression, receptor signaling, and correlation with axon regeneration
-
DOI 10.1002/glia.10315
-
Sandvig A, Berry M, Barrett LB, Butt A, Logan A. Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration. Glia 2004;46:225-251. (Pubitemid 38679204)
-
(2004)
GLIA
, vol.46
, Issue.3
, pp. 225-251
-
-
Sandvig, A.1
Berry, M.2
Barrett, L.B.3
Butt, A.4
Logan, A.5
-
39
-
-
18944372230
-
Rho kinase, a promising drug target for neurological disorders
-
DOI 10.1038/nrd1719
-
Mueller BK, Mack H, Teusch N. Rho kinase, a promising drug target for neurological disorders. Nat Rev Drug Discov 2005;4:387-398. (Pubitemid 40704122)
-
(2005)
Nature Reviews Drug Discovery
, vol.4
, Issue.5
, pp. 387-398
-
-
Mueller, B.K.1
Mack, H.2
Teusch, N.3
-
40
-
-
58249084150
-
Efficacy of Rho-kinase inhibition in promoting cell survival and reducing reactive gliosis in the rodent retina
-
Tura A, Schuettauf F, Monnier PP, Bartz-Schmidt KU, Henke-Fahle S. Efficacy of Rho-kinase inhibition in promoting cell survival and reducing reactive gliosis in the rodent retina. Invest Ophthalmol Vis Sci 2009;50:452-461.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 452-461
-
-
Tura, A.1
Schuettauf, F.2
Monnier, P.P.3
Bartz-Schmidt, K.U.4
Henke-Fahle, S.5
-
41
-
-
34247210251
-
A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats
-
DOI 10.1016/j.expneurol.2007.02.002, PII S0014488607000611
-
Sagawa H, Terasaki H, Nakamura M et al. A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats. Exp Neurol 2007;205:230-240. (Pubitemid 46617509)
-
(2007)
Experimental Neurology
, vol.205
, Issue.1
, pp. 230-240
-
-
Sagawa, H.1
Terasaki, H.2
Nakamura, M.3
Ichikawa, M.4
Yata, T.5
Tokita, Y.6
Watanabe, M.7
|