메뉴 건너뛰기




Volumn 36, Issue 10, 2011, Pages 964-970

Effects of Y-39983, a selective Rho-associated protein kinase inhibitor, on blood flow in optic nerve head in rabbits and axonal regeneration of retinal ganglion cells in rats

Author keywords

Axonal regeneration; Glaucoma; Ocular blood flow; Retinal ganglion cells; ROCK; Y 39983

Indexed keywords

RHO KINASE INHIBITOR; SODIUM CHLORIDE; UNCLASSIFIED DRUG; Y 39983;

EID: 80053320552     PISSN: 02713683     EISSN: 14602202     Source Type: Journal    
DOI: 10.3109/02713683.2011.599106     Document Type: Article
Times cited : (55)

References (41)
  • 1
    • 2442643730 scopus 로고    scopus 로고
    • Primary open-angle glaucoma
    • DOI 10.1016/S0140-6736(04)16257-0, PII S0140673604162570
    • Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet 2004;363:1711-1720. (Pubitemid 38670330)
    • (2004) Lancet , vol.363 , Issue.9422 , pp. 1711-1720
    • Weinreb, R.N.1    Tee Khaw, P.2
  • 2
    • 0028038213 scopus 로고
    • Mechanisms of optic nerve damage in primary open angle glaucoma
    • DOI 10.1016/S0039-6257(05)80042-6
    • Fechtner RD, Weinreb RN. Mechanisms of optic nerve damage in primary open angle glaucoma. Surv Ophthalmol 1994;39:23-42. (Pubitemid 24243493)
    • (1994) Survey of Ophthalmology , vol.39 , Issue.1 , pp. 23-42
    • Fechtner, R.D.1    Weinreb, R.N.2
  • 3
    • 0028433377 scopus 로고
    • The vascular concept of glaucoma
    • DOI 10.1016/0039-6257(94)90041-8
    • Flammer J. The vascular concept of glaucoma. Surv Ophthalmol 1994;38 Suppl:S3-S6. (Pubitemid 124017796)
    • (1994) Survey of Ophthalmology , vol.38 , Issue.SUPPL. 1
    • Flammer, J.1
  • 5
    • 0027973532 scopus 로고
    • Factors contributing to the progression of visual field damage in eyes with normal-tension glaucoma
    • Araie M, Sekine M, Suzuki Y, Koseki N. Factors contributing to the progression of visual field damage in eyes with normal-tension glaucoma. Ophthalmology 1994;101:1440-1444. (Pubitemid 24319293)
    • (1994) Ophthalmology , vol.101 , Issue.8 , pp. 1440-1444
    • Araie, M.1    Sekine, M.2    Suzuki, Y.3    Koseki, N.4
  • 6
    • 0029791373 scopus 로고    scopus 로고
    • The small GTPase Rho: Cellular functions and signal transduction
    • Narumiya S. The small GTPase Rho: cellular functions and signal transduction. J Biochem 1996;120:215-228. (Pubitemid 26335910)
    • (1996) Journal of Biochemistry , vol.120 , Issue.2 , pp. 215-228
    • Narumiya, S.1
  • 7
    • 0030612748 scopus 로고    scopus 로고
    • Rho effecters and reorganization of actin cytoskeleton
    • DOI 10.1016/S0014-5793(97)00317-7, PII S0014579397003177
    • Narumiya S, Ishizaki T, Watanabe N. Rho effectors and reorganization of actin cytoskeleton. FEBS Lett 1997;410: 68-72. (Pubitemid 27283386)
    • (1997) FEBS Letters , vol.410 , Issue.1 , pp. 68-72
    • Narumiya, S.1    Ishizaki, T.2    Watanabe, N.3
  • 10
    • 0027509362 scopus 로고
    • Regulation of cytoplasmic division of Xenopus embryo by Rho p21 and its inhibitory GDP/GTP exchange protein Rho GDI
    • Kishi K, Sasaki T, Kuroda S, Itoh T, Takai Y. Regulation of cytoplasmic division of Xenopus embryo by Rho p21 and its inhibitory GDP/GTP exchange protein (Rho GDI).J Cell Biol 1993;120:1187-1195.
    • (1993) J. Cell Biol. , vol.120 , pp. 1187-1195
    • Kishi, K.1    Sasaki, T.2    Kuroda, S.3    Itoh, T.4    Takai, Y.5
  • 11
    • 0026806476 scopus 로고
    • Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction
    • Hirata K, Kikuchi A, Sasaki T et al. Involvement of rho p21 in the GTP-enhanced calcium ion sensitivity of smooth muscle contraction. J Biol Chem 1992;267:8719-8722.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8719-8722
    • Hirata, K.1    Kikuchi, A.2    Sasaki, T.3
  • 12
    • 0030071903 scopus 로고    scopus 로고
    • Role of guanine nucleotide- binding proteins-ras-family or trimeric proteins or both-in Ca2+ sensitization of smooth muscle
    • USA
    • Gong MC, Iizuka K, Nixon G et al. Role of guanine nucleotide- binding proteins-ras-family or trimeric proteins or both-in Ca2+ sensitization of smooth muscle. Proc Natl Acad Sci USA 1996;93:1340-1345.
    • (1996) Proc. Natl. Acad. Sci. , vol.93 , pp. 1340-1345
    • Gong, M.C.1    Iizuka, K.2    Nixon, G.3
  • 15
    • 0026074852 scopus 로고
    • Morphology of the trabecular meshwork and inner-wall endothelium after cationized ferritin perfusion in the monkey eye
    • Epstein DL, Rohen JW. Morphology of the trabecular meshwork and inner-wall endothelium after cationized ferritin perfusion in the monkey eye. Invest Ophthalmol Vis Sci 1991;32:160-171.
    • (1991) Invest. Ophthalmol. Vis. Sci. , vol.32 , pp. 160-171
    • Epstein, D.L.1    Rohen, J.W.2
  • 19
    • 0035726683 scopus 로고    scopus 로고
    • Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase
    • DOI 10.1076/ceyr.22.6.470.5489
    • Waki M, Yoshida Y, Oka T, Azuma M. Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase. Curr Eye Res 2001;22:470-474. (Pubitemid 34253206)
    • (2001) Current Eye Research , vol.22 , Issue.6 , pp. 470-474
    • Waki, M.1    Yoshida, Y.2    Oka, T.3    Azuma, M.4
  • 22
    • 40849130917 scopus 로고    scopus 로고
    • Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers
    • DOI 10.1001/archophthalmol.2007.76
    • Tanihara H, Inatani M, Honjo M, Tokushige H, Azuma J, Araie M. Intraocular pressure-lowering effects and safety of topical administration of a selective ROCK inhibitor, SNJ-1656, in healthy volunteers. Arch Ophthalmol 2008;126:309-315. (Pubitemid 351398453)
    • (2008) Archives of Ophthalmology , vol.126 , Issue.3 , pp. 309-315
    • Tanihara, H.1    Inatani, M.2    Honjo, M.3    Tokushige, H.4    Azuma, J.5    Araie, M.6
  • 24
    • 0027250451 scopus 로고
    • An application of laser speckle phenomenon for noninvasive two-dimensional evaluation of microcirculation in ocular fundus a preliminary report
    • Tamaki Y, Kawamoto E, Araie M, Eguchi S, Fujii H. An application of laser speckle phenomenon for noninvasive twodimensional evaluation of microcirculation in ocular fundus-a preliminary report. Jpn J Ophthalmol 1993;37:178-186. (Pubitemid 23230300)
    • (1993) Japanese Journal of Ophthalmology , vol.37 , Issue.2 , pp. 178-186
    • Tamaki, Y.1    Kawamoto, E.2    Araie, M.3    Eguchi, S.4    Fujii, H.5
  • 25
    • 0028951869 scopus 로고
    • Non-contact two-dimensional measurement of tissue circulation in choroid and optic nerve head using laser speckle phenomenon
    • Tamaki Y, Araie M, Kawamoto E, Eguchi S, Fujii H. Non-contact, two-dimensional measurement of tissue circulation in choroid and optic nerve head using laser speckle phenomenon. Exp Eye Res 1995;60:373-383.
    • (1995) Exp. Eye Res. , vol.60 , pp. 373-383
    • Tamaki, Y.1    Araie, M.2    Kawamoto, E.3    Eguchi, S.4    Fujii, H.5
  • 26
    • 0024109174 scopus 로고
    • Immunological morphological and electrophysiological variation among retinal ganglion cells purified by panning
    • Barres BA, Silverstein BE, Corey DP, Chun LL. Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning. Neuron 1988;1:791-803.
    • (1988) Neuron , vol.1 , pp. 791-803
    • Barres, B.A.1    Silverstein, B.E.2    Corey, D.P.3    Chun, L.L.4
  • 28
    • 17744397579 scopus 로고    scopus 로고
    • Contribution of ROCK in contraction of trabecular meshwork: Proposed mechanism for regulating aqueous outflow in monkey and human eyes
    • DOI 10.1002/jps.20285
    • Nakajima E, Nakajima T, Minagawa Y, Shearer TR, Azuma M. Contribution of ROCK in contraction of trabecular meshwork: proposed mechanism for regulating aqueous outflow in monkey and human eyes. J Pharm Sci 2005;94:701-708. (Pubitemid 40577304)
    • (2005) Journal of Pharmaceutical Sciences , vol.94 , Issue.4 , pp. 701-708
    • Nakajima, E.1    Nakajima, T.2    Minagawa, Y.3    Shearer, T.R.4    Azuma, M.5
  • 30
    • 0036785777 scopus 로고    scopus 로고
    • Topical nipradilol: Effects on optic nerve head circulation in humans and periocular distribution in monkeys
    • Mizuno K, Koide T, Saito N et al. Topical nipradilol: effects on optic nerve head circulation in humans and periocular distribution in monkeys. Invest Ophthalmol Vis Sci 2002;43:3243-3250.
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 3243-3250
    • Mizuno, K.1    Koide, T.2    Saito, N.3
  • 32
    • 18244383304 scopus 로고    scopus 로고
    • Time course of changes in optic nerve head circulation after acute reduction in intraocular pressure
    • DOI 10.1167/iovs.04-1082
    • Takayama J, Tomidokoro A, Tamaki Y, Araie M. Time course of changes in optic nerve head circulation after acute reduction in intraocular pressure. Invest Ophthalmol Vis Sci 2005;46:1409-1419. (Pubitemid 41685883)
    • (2005) Investigative Ophthalmology and Visual Science , vol.46 , Issue.4 , pp. 1409-1419
    • Takayama, J.1    Tomidokoro, A.2    Tamaki, Y.3    Araie, M.4
  • 33
    • 0034809474 scopus 로고    scopus 로고
    • A hypothesis to explain ganglion cell death caused by vascular insults at the optic nerve head: Possible implication for the treatment of glaucoma
    • DOI 10.1136/bjo.85.10.1252
    • Osborne NN, Melena J, Chidlow G, Wood JP. A hypothesis to explain ganglion cell death caused by vascular insults at the optic nerve head: possible implication for the treatment of glaucoma. Br J Ophthalmol 2001;85:1252-1259. (Pubitemid 32929554)
    • (2001) British Journal of Ophthalmology , vol.85 , Issue.10 , pp. 1252-1259
    • Osborne, N.N.1    Melena, J.2    Chidlow, G.3    Wood, J.P.M.4
  • 35
    • 79952230532 scopus 로고    scopus 로고
    • Effects of fasudil a Rho-associated protein kinase inhibitor on optic nerve head blood flow in rabbits
    • Sugiyama T, Shibata M, Kajiura S et al. Effects of fasudil, a Rho-associated protein kinase inhibitor, on optic nerve head blood flow in rabbits. Invest Ophthalmol Vis Sci 2011;52:64-69.
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 64-69
    • Sugiyama, T.1    Shibata, M.2    Kajiura, S.3
  • 36
    • 34249694646 scopus 로고    scopus 로고
    • Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma
    • DOI 10.2165/00063030-200721030-00004
    • Rao VP, Epstein DL. Rho GTPase/Rho kinase inhibition as a novel target for the treatment of glaucoma. BioDrugs 2007;21:167-177. (Pubitemid 46827850)
    • (2007) BioDrugs , vol.21 , Issue.3 , pp. 167-177
    • Rao, V.P.1    Epstein, D.L.2
  • 37
    • 0037408391 scopus 로고    scopus 로고
    • The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI
    • Yamashita T, Tohyama M. The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI. Nat Neurosci 2003;6:461-467. (Pubitemid 36514693)
    • (2003) Nature Neuroscience , vol.6 , Issue.5 , pp. 461-467
    • Yamashita, T.1    Tohyama, M.2
  • 38
    • 2442693021 scopus 로고    scopus 로고
    • Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: Expression, receptor signaling, and correlation with axon regeneration
    • DOI 10.1002/glia.10315
    • Sandvig A, Berry M, Barrett LB, Butt A, Logan A. Myelin-, reactive glia-, and scar-derived CNS axon growth inhibitors: expression, receptor signaling, and correlation with axon regeneration. Glia 2004;46:225-251. (Pubitemid 38679204)
    • (2004) GLIA , vol.46 , Issue.3 , pp. 225-251
    • Sandvig, A.1    Berry, M.2    Barrett, L.B.3    Butt, A.4    Logan, A.5
  • 39
    • 18944372230 scopus 로고    scopus 로고
    • Rho kinase, a promising drug target for neurological disorders
    • DOI 10.1038/nrd1719
    • Mueller BK, Mack H, Teusch N. Rho kinase, a promising drug target for neurological disorders. Nat Rev Drug Discov 2005;4:387-398. (Pubitemid 40704122)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.5 , pp. 387-398
    • Mueller, B.K.1    Mack, H.2    Teusch, N.3
  • 41
    • 34247210251 scopus 로고    scopus 로고
    • A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats
    • DOI 10.1016/j.expneurol.2007.02.002, PII S0014488607000611
    • Sagawa H, Terasaki H, Nakamura M et al. A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats. Exp Neurol 2007;205:230-240. (Pubitemid 46617509)
    • (2007) Experimental Neurology , vol.205 , Issue.1 , pp. 230-240
    • Sagawa, H.1    Terasaki, H.2    Nakamura, M.3    Ichikawa, M.4    Yata, T.5    Tokita, Y.6    Watanabe, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.