Dexamethasone stiffens trabecular meshwork, trabecular meshwork cells, and matrix

Investigative Ophthalmology and Visual Science

Volumn 56, Issue 8, 2015, Pages 4447-4459

  Raghunathan, Vijay Krishna ^a   Morgan, Joshua T ^a   Park, Shin Ae ^a   Weber, Darren ^b   Phinney, Brett S ^b   Murphy, Christopher J ^a,c   Russell, Paul ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cell and matrix mechanics; Elastic modulus; Extracellular matrix; Proteomics; Steroid induced glaucoma

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; DECORIN; DEXAMETHASONE; F ACTIN; FIBRILLIN; FIBRONECTIN; GELATINASE A; MITOGEN ACTIVATED PROTEIN KINASE; MYOCILIN; NUCLEAR MATRIX PROTEIN; SOMATOMEDIN BINDING PROTEIN 2; ACTIN; GLUCOCORTICOID; SCLEROPROTEIN;

ADULT; ANIMAL EXPERIMENT; AQUEOUS HUMOR OUTFLOW; ARTICLE; ATOMIC FORCE MICROSCOPY; BIOMECHANICS; CELL COMPOSITION; CELL STIFFNESS; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR MATRIX; FEMALE; GENE ONTOLOGY; GLAUCOMA; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTRAOCULAR PRESSURE; MOLECULAR DYNAMICS; NEW ZEALAND WHITE (RABBIT); NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; RADIOIMMUNOPRECIPITATION; TRABECULAR MESHWORK; UPREGULATION; WESTERN BLOTTING; YOUNG MODULUS; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; ELASTICITY; GENE EXPRESSION PROFILING; METABOLISM; PHYSIOLOGY; RABBIT; SIGNAL TRANSDUCTION;

ACTINS; ANIMALS; BIOMECHANICAL PHENOMENA; BLOTTING, WESTERN; CELLS, CULTURED; DEXAMETHASONE; ELASTICITY; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION PROFILING; GLUCOCORTICOIDS; HUMANS; MAP KINASE SIGNALING SYSTEM; PROTEOMICS; RABBITS; TRABECULAR MESHWORK;

EID: 84939856414     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.15-16739     Document Type: Article

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