Rho-ROCK inhibition in the treatment of spinal cord injury

World Neurosurgery

Volumn 82, Issue 3, 2014, Pages E535-E539

  Forgione, Nicole ^a   Fehlings, Michael G ^b  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Mechanisms of action; Rho inhibition; Rho ROCK inhibition; Spinal cord injury; Treatment

Indexed keywords

CETHRIN; MYELIN; RHO KINASE INHIBITOR; UNCLASSIFIED DRUG; BOTULINUM TOXIN; ENZYME INHIBITOR; EXOENZYME C3, CLOSTRIDIUM BOTULINUM; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE INHIBITOR; RHO KINASE;

ARTICLE; CLINICAL EVALUATION; DRUG MECHANISM; IN VITRO STUDY; LOCOMOTION; NERVE FIBER REGENERATION; NEUROPROTECTION; NONHUMAN; PATHOPHYSIOLOGY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); RETINA GANGLION CELL; SPINAL CORD INJURY; SPROUTING; THORACIC SPINAL CORD; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; HUMAN; SIGNAL TRANSDUCTION; SPINAL CORD INJURIES;

ADP RIBOSE TRANSFERASES; ANIMALS; BOTULINUM TOXINS; ENZYME INHIBITORS; HUMANS; NEUROPROTECTIVE AGENTS; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION; SPINAL CORD INJURIES;

EID: 84922239821     PISSN: 18788750     EISSN: 18788769     Source Type: Journal    
DOI: 10.1016/j.wneu.2013.01.009     Document Type: Review

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