Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats

Journal of Neuroscience

Volumn 25, Issue 5, 2005, Pages 1113-1121

  Bertrand, Johanne ^a   Winton, Matthew J ^a   Rodriguez Hernandez, Nieves ^c   Campenot, Robert B ^b   McKerracher, Lisa ^a,c  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF ALBERTA   (Canada)

^c BioAxone Thérapeutique   (Canada)

Author keywords

Axon regeneration; Compartmented culture; Optic nerve injury; RGC survival; Slow axonal transport; Sympathetic neuron

Indexed keywords

CYTOSKELETON PROTEIN; MYELIN ASSOCIATED GLYCOPROTEIN; PROTEIN INHIBITOR; RHO ANTAGONIST C3-05; RHO ANTAGONIST C3-07; RHO FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL REGENERATION; CONTROLLED STUDY; FEMALE; GROWTH INHIBITION; NERVE CELL; NERVE CELL CULTURE; NERVE FIBER; NERVE FIBER GROWTH; NERVE FIBER TRANSECTION; NERVE FIBER TRANSPORT; NEUROPROTECTION; NONHUMAN; OPTIC NERVE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL;

ADP RIBOSE TRANSFERASES; ANIMALS; AXONS; CELL SURVIVAL; CELLS, CULTURED; CICATRIX; CULTURE MEDIA; CYTOSKELETAL PROTEINS; FEMALE; INJECTIONS; MICROSURGERY; MYELIN-ASSOCIATED GLYCOPROTEIN; NERVE CRUSH; NERVE REGENERATION; NERVE TISSUE PROTEINS; NEURITES; NEUROPROTECTIVE AGENTS; OPTIC NERVE; OPTIC NERVE INJURIES; RATS; RATS, SPRAGUE-DAWLEY; RETINAL GANGLION CELLS; RHO GTP-BINDING PROTEINS; SUPERIOR CERVICAL GANGLION; VITREOUS BODY;

EID: 13944274451     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3931-04.2005     Document Type: Article

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