-
2
-
-
77955293560
-
Parkinson's disease and cancer risk: A systematic review and meta-analysis
-
Bajaj A, Driver JA, Schernhammer ES. Parkinson's disease and cancer risk: a systematic review and meta-analysis. Cancer Causes Control. 2010;21:697-707.
-
(2010)
Cancer Causes Control
, vol.21
, pp. 697-707
-
-
Bajaj, A.1
Driver, J.A.2
Schernhammer, E.S.3
-
3
-
-
84892723201
-
Inverse and direct cancer comorbidity in people with central nervous system disorders: A meta-analysis of cancer incidence in 577,013 participants of 50 observational studies
-
Catalá-López F, Suárez-Pinilla M, Suárez-Pinilla P, Valderas JM, Gómez-Beneyto M, Martinez S, et al. Inverse and direct cancer comorbidity in people with central nervous system disorders: a meta-analysis of cancer incidence in 577,013 participants of 50 observational studies. Psychother Psychosom. 2014;83:89-105.
-
(2014)
Psychother Psychosom
, vol.83
, pp. 89-105
-
-
Catalá-López, F.1
Suárez-Pinilla, M.2
Suárez-Pinilla, P.3
Valderas, J.M.4
Gómez-Beneyto, M.5
Martinez, S.6
-
4
-
-
33747147096
-
Malignant melanoma and other types of cancer preceding Parkinson disease
-
Olsen JH, Friis S, Frederiksen K. Malignant melanoma and other types of cancer preceding Parkinson disease. Epidemiology. 2006;17:582-7.
-
(2006)
Epidemiology
, vol.17
, pp. 582-587
-
-
Olsen, J.H.1
Friis, S.2
Frederiksen, K.3
-
5
-
-
84891353678
-
Parkinson's disease and cancer: A register-based family study
-
Wirdefeldt K, Weibull CE, Chen H, Kamel F, Lundholm C, Fang F, et al. Parkinson's disease and cancer: A register-based family study. Am J Epidemiol. 2014;179:85-94.
-
(2014)
Am J Epidemiol
, vol.179
, pp. 85-94
-
-
Wirdefeldt, K.1
Weibull, C.E.2
Chen, H.3
Kamel, F.4
Lundholm, C.5
Fang, F.6
-
6
-
-
85027948510
-
Differential risks of cancer types in people with Parkinson's disease: A national record-linkage study
-
Ong ELH, Goldacre R, Goldacre M. Differential risks of cancer types in people with Parkinson's disease: a national record-linkage study. Eur J Cancer. 2014;50:2456-62.
-
(2014)
Eur J Cancer
, vol.50
, pp. 2456-2462
-
-
Ong, E.L.H.1
Goldacre, R.2
Goldacre, M.3
-
7
-
-
84964693236
-
Association between Parkinson disease and risk of cancer in Taiwan
-
Lin P-Y, Chang S-N, Hsiao T-H, Huang B-T, Lin C-H, Yang P-C. Association Between Parkinson Disease and Risk of Cancer in Taiwan. JAMA Oncol. 2015;1(5):633-40.
-
(2015)
JAMA Oncol
, vol.1
, Issue.5
, pp. 633-640
-
-
Lin, P.-Y.1
Chang, S.-N.2
Hsiao, T.-H.3
Huang, B.-T.4
Lin, C.-H.5
Yang, P.-C.6
-
8
-
-
80053481083
-
Analysis of Parkinson's disease and subsequent cancer risk in Taiwan: A nationwide population-based cohort study
-
Sun L-M, Liang J-A, Chang S-N, Sung F-C, Muo C-H, Kao C-H. Analysis of Parkinson's disease and subsequent cancer risk in Taiwan: a nationwide population-based cohort study. Neuroepidemiology. 2011;37:114-9.
-
(2011)
Neuroepidemiology
, vol.37
, pp. 114-119
-
-
Sun, L.-M.1
Liang, J.-A.2
Chang, S.-N.3
Sung, F.-C.4
Muo, C.-H.5
Kao, C.-H.6
-
9
-
-
13244298209
-
Atypical cancer pattern in patients with Parkinson's disease
-
Olsen JH, Friis S, Frederiksen K, McLaughlin JK, Mellemkjaer L, Møller H. Atypical cancer pattern in patients with Parkinson's disease. Br J Cancer. 2005;92:201-5.
-
(2005)
Br J Cancer
, vol.92
, pp. 201-205
-
-
Olsen, J.H.1
Friis, S.2
Frederiksen, K.3
McLaughlin, J.K.4
Mellemkjaer, L.5
Møller, H.6
-
10
-
-
0029002226
-
Occurrence of different cancers in patients with Parkinson's disease
-
Møller H, Mellemkjaer L, McLaughlin JK, Olsen JH. Occurrence of different cancers in patients with Parkinson's disease. BMJ. 1995;310:1500-1.
-
(1995)
BMJ
, vol.310
, pp. 1500-1501
-
-
Møller, H.1
Mellemkjaer, L.2
McLaughlin, J.K.3
Olsen, J.H.4
-
11
-
-
84871243120
-
Shared predispositions of parkinsonism and cancer: A population-based pedigree-linked study
-
Kareus SA, Figueroa KP, Cannon-Albright LA, Pulst SM. Shared predispositions of parkinsonism and cancer: a population-based pedigree-linked study. Arch Neurol. 2012;69:1572-7.
-
(2012)
Arch Neurol
, vol.69
, pp. 1572-1577
-
-
Kareus, S.A.1
Figueroa, K.P.2
Cannon-Albright, L.A.3
Pulst, S.M.4
-
12
-
-
34250888235
-
A prospective cohort study of cancer incidence following the diagnosis of Parkinson's disease
-
Driver JA, Logroscino G, Buring JE, Gaziano JM, Kurth T. A prospective cohort study of cancer incidence following the diagnosis of Parkinson's disease. Cancer Epidemiol Biomarkers Prev. 2007;16:1260-5.
-
(2007)
Cancer Epidemiol Biomarkers Prev
, vol.16
, pp. 1260-1265
-
-
Driver, J.A.1
Logroscino, G.2
Buring, J.E.3
Gaziano, J.M.4
Kurth, T.5
-
13
-
-
76549102193
-
Cancer in patients with motor neuron disease, multiple sclerosis and Parkinson's disease: Record linkage studies
-
Fois AF, Wotton CJ, Yeates D, Turner MR, Goldacre MJ. Cancer in patients with motor neuron disease, multiple sclerosis and Parkinson's disease: record linkage studies. J Neurol Neurosurg Psychiatry. 2010;81:215-21.
-
(2010)
J Neurol Neurosurg Psychiatry
, vol.81
, pp. 215-221
-
-
Fois, A.F.1
Wotton, C.J.2
Yeates, D.3
Turner, M.R.4
Goldacre, M.J.5
-
14
-
-
72249087540
-
Family history of melanoma and Parkinson disease risk
-
Gao X, Simon KC, Han J, Schwarzschild MA, Ascherio A. Family history of melanoma and Parkinson disease risk. Neurology. 2009;73:1286-91.
-
(2009)
Neurology
, vol.73
, pp. 1286-1291
-
-
Gao, X.1
Simon, K.C.2
Han, J.3
Schwarzschild, M.A.4
Ascherio, A.5
-
15
-
-
84865325214
-
Malignant melanoma, breast cancer and other cancers in patients with Parkinson's disease
-
Rugbjerg K, Kathrine R, Søren F, Lassen CF, Beate R, Olsen JH. Malignant melanoma, breast cancer and other cancers in patients with Parkinson's disease. Int J Cancer. 2012;131:1904-11.
-
(2012)
Int J Cancer
, vol.131
, pp. 1904-1911
-
-
Rugbjerg, K.1
Kathrine, R.2
Søren, F.3
Lassen, C.F.4
Beate, R.5
Olsen, J.H.6
-
16
-
-
79958696375
-
Meta-analysis of the relationship between Parkinson disease and melanoma
-
Liu R, Gao X, Lu Y, Chen H. Meta-analysis of the relationship between Parkinson disease and melanoma. Neurology. 2011;76:2002-9.
-
(2011)
Neurology
, vol.76
, pp. 2002-2009
-
-
Liu, R.1
Gao, X.2
Lu, Y.3
Chen, H.4
-
18
-
-
68349128669
-
Parkinson's disease, levodopa-use and the risk of melanoma
-
Vermeij J-D, Winogrodzka A, Trip J, Weber WEJ. Parkinson's disease, levodopa-use and the risk of melanoma. Parkinsonism Relat Disord. 2009;15:551-3.
-
(2009)
Parkinsonism Relat Disord
, vol.15
, pp. 551-553
-
-
Vermeij, J.-D.1
Winogrodzka, A.2
Trip, J.3
Weber, W.E.J.4
-
19
-
-
33746150380
-
Melanoma, Parkinson's disease and levodopa: Causal or spurious link? A review of the literature
-
Zanetti R, Loria D, Rosso S. Melanoma, Parkinson's disease and levodopa: causal or spurious link? A review of the literature. Melanoma Res. 2006;16:201-6.
-
(2006)
Melanoma Res
, vol.16
, pp. 201-206
-
-
Zanetti, R.1
Loria, D.2
Rosso, S.3
-
20
-
-
79953196889
-
The association between Parkinson's disease and melanoma
-
Pan T, Li X, Jankovic J. The association between Parkinson's disease and melanoma. Int J Cancer. 2011;128:2251-60.
-
(2011)
Int J Cancer
, vol.128
, pp. 2251-2260
-
-
Pan, T.1
Li, X.2
Jankovic, J.3
-
21
-
-
78349276561
-
Common pathogenic pathways in melanoma and Parkinson disease
-
Paisán-Ruiz C, Houlden H. Common pathogenic pathways in melanoma and Parkinson disease. Neurology. 2010;75:1653-5.
-
(2010)
Neurology
, vol.75
, pp. 1653-1655
-
-
Paisán-Ruiz, C.1
Houlden, H.2
-
22
-
-
84901950458
-
Sphingolipid lysosomal storage disorders
-
Platt FM. Sphingolipid lysosomal storage disorders. Nature. 2014;510:68-75.
-
(2014)
Nature
, vol.510
, pp. 68-75
-
-
Platt, F.M.1
-
23
-
-
84878495489
-
Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines
-
Chorfa A, Bétemps D, Morignat E, Lazizzera C, Hogeveen K, Andrieu T, et al. Specific pesticide-dependent increases in α-synuclein levels in human neuroblastoma (SH-SY5Y) and melanoma (SK-MEL-2) cell lines. Toxicol Sci. 2013;133:289-97.
-
(2013)
Toxicol Sci
, vol.133
, pp. 289-297
-
-
Chorfa, A.1
Bétemps, D.2
Morignat, E.3
Lazizzera, C.4
Hogeveen, K.5
Andrieu, T.6
-
24
-
-
84872003490
-
Meta-analysis of early nonmotor features and risk factors for Parkinson disease
-
Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Giovannoni G, Lees AJ, et al. Meta-analysis of early nonmotor features and risk factors for Parkinson disease. Ann Neurol. 2012;72:893-901.
-
(2012)
Ann Neurol
, vol.72
, pp. 893-901
-
-
Noyce, A.J.1
Bestwick, J.P.2
Silveira-Moriyama, L.3
Hawkes, C.H.4
Giovannoni, G.5
Lees, A.J.6
-
25
-
-
0344196900
-
Risk of melanoma in relation to smoking, alcohol intake, and other factors in a large occupational cohort
-
Freedman DM, Michal Freedman D, Alice S, Doody MM, Sowmya Rao R, Linet MS. Risk of melanoma in relation to smoking, alcohol intake, and other factors in a large occupational cohort. Cancer Causes Control. 2003;14:847-57.
-
(2003)
Cancer Causes Control
, vol.14
, pp. 847-857
-
-
Freedman, D.M.1
Michal Freedman, D.2
Alice, S.3
Doody, M.M.4
Sowmya Rao, R.5
Linet, M.S.6
-
26
-
-
79956282532
-
Cigarette smoking and the risk of incident and fatal melanoma in a large prospective cohort study
-
DeLancey JO, Hannan LM, Gapstur SM, Thun MJ. Cigarette smoking and the risk of incident and fatal melanoma in a large prospective cohort study. Cancer Causes Control. 2011;22:937-42.
-
(2011)
Cancer Causes Control
, vol.22
, pp. 937-942
-
-
DeLancey, J.O.1
Hannan, L.M.2
Gapstur, S.M.3
Thun, M.J.4
-
27
-
-
84872157908
-
Smoking and risk of skin cancer: A prospective analysis and a meta-analysis
-
Song F, Qureshi AA, Gao X, Li T, Han J. Smoking and risk of skin cancer: a prospective analysis and a meta-analysis. Int J Epidemiol. 2012;41:1694-705.
-
(2012)
Int J Epidemiol
, vol.41
, pp. 1694-1705
-
-
Song, F.1
Qureshi, A.A.2
Gao, X.3
Li, T.4
Han, J.5
-
28
-
-
84929590409
-
Lifestyle, family history, and risk of idiopathic Parkinson disease: A large Danish case-control study
-
Kenborg L, Lassen CF, Ritz B, Andersen KK, Christensen J, Schernhammer ES, et al. Lifestyle, family history, and risk of idiopathic Parkinson disease: a large Danish case-control study. Am J Epidemiol. 2015;181:808-16.
-
(2015)
Am J Epidemiol
, vol.181
, pp. 808-816
-
-
Kenborg, L.1
Lassen, C.F.2
Ritz, B.3
Andersen, K.K.4
Christensen, J.5
Schernhammer, E.S.6
-
29
-
-
84899740082
-
A case-control study of the protective effect of alcohol, coffee, and cigarette consumption on Parkinson disease risk: Time-since-cessation modifies the effect of tobacco smoking
-
Van der Mark M, Nijssen PCG, Vlaanderen J, Huss A, Mulleners WM, Sas AMG, et al. A case-control study of the protective effect of alcohol, coffee, and cigarette consumption on Parkinson disease risk: time-since-cessation modifies the effect of tobacco smoking. PLoS One. 2014;9:e95297.
-
(2014)
PLoS One
, vol.9
-
-
Van Der Mark, M.1
Nijssen, P.C.G.2
Vlaanderen, J.3
Huss, A.4
Mulleners, W.M.5
Sas, A.M.G.6
-
30
-
-
15244339160
-
Neuromelanin in human dopamine neurons: Comparison with peripheral melanins and relevance to Parkinson's disease
-
Fedorow H, Tribl F, Halliday G, Gerlach M, Riederer P, Double KL. Neuromelanin in human dopamine neurons: comparison with peripheral melanins and relevance to Parkinson's disease. Prog Neurobiol. 2005;75:109-24.
-
(2005)
Prog Neurobiol
, vol.75
, pp. 109-124
-
-
Fedorow, H.1
Tribl, F.2
Halliday, G.3
Gerlach, M.4
Riederer, P.5
Double, K.L.6
-
31
-
-
0035851917
-
Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex
-
Sprong H, Degroote S, Claessens T, van Drunen J, Oorschot V, Westerink BH, et al. Glycosphingolipids are required for sorting melanosomal proteins in the Golgi complex. J Cell Biol. 2001;155:369-80.
-
(2001)
J Cell Biol
, vol.155
, pp. 369-380
-
-
Sprong, H.1
Degroote, S.2
Claessens, T.3
Van Drunen, J.4
Oorschot, V.5
Westerink, B.H.6
-
32
-
-
84856964851
-
Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations
-
Paisán-Ruiz C, Li A, Schneider SA, Holton JL, Johnson R, Kidd D, et al. Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations. Neurobiol Aging. 2012;33:814-23.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 814-823
-
-
Paisán-Ruiz, C.1
Li, A.2
Schneider, S.A.3
Holton, J.L.4
Johnson, R.5
Kidd, D.6
-
33
-
-
60849121924
-
Characterization of PLA2G6 as a locus for dystonia-parkinsonism
-
Paisan-Ruiz C, Bhatia KP, Li A, Hernandez D, Davis M, Wood NW, et al. Characterization of PLA2G6 as a locus for dystonia-parkinsonism. Ann Neurol. 2009;65:19-23.
-
(2009)
Ann Neurol
, vol.65
, pp. 19-23
-
-
Paisan-Ruiz, C.1
Bhatia, K.P.2
Li, A.3
Hernandez, D.4
Davis, M.5
Wood, N.W.6
-
34
-
-
68149100807
-
Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi
-
Falchi M, Bataille V, Hayward NK, Duffy DL, Bishop JAN, Pastinen T, et al. Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat Genet. 2009;41:915-9.
-
(2009)
Nat Genet
, vol.41
, pp. 915-919
-
-
Falchi, M.1
Bataille, V.2
Hayward, N.K.3
Duffy, D.L.4
Bishop, J.A.N.5
Pastinen, T.6
-
36
-
-
77955088249
-
Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders
-
Piccinini M, Scandroglio F, Prioni S, Buccinnà B, Loberto N, Aureli M, et al. Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders. Mol Neurobiol. 2010;41:314-40.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 314-340
-
-
Piccinini, M.1
Scandroglio, F.2
Prioni, S.3
Buccinnà, B.4
Loberto, N.5
Aureli, M.6
-
37
-
-
0242285663
-
Neuromelanin of the substantia nigra: A neuronal black hole with protective and toxic characteristics
-
Zecca L, Luigi Z, Zucca FA, Henrik W, David S. Neuromelanin of the substantia nigra: a neuronal black hole with protective and toxic characteristics. Trends Neurosci. 2003;26:578-80.
-
(2003)
Trends Neurosci
, vol.26
, pp. 578-580
-
-
Zecca, L.1
Luigi, Z.2
Zucca, F.A.3
Henrik, W.4
David, S.5
-
38
-
-
33747689949
-
Melanin and nicotine: A review of the literature
-
Yerger VB, Malone RE. Melanin and nicotine: A review of the literature. Nicotine Tob Res. 2006;8:487-98.
-
(2006)
Nicotine Tob Res
, vol.8
, pp. 487-498
-
-
Yerger, V.B.1
Malone, R.E.2
-
40
-
-
84899889312
-
Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo
-
Rockenstein E, Nuber S, Overk CR, Ubhi K, Mante M, Patrick C, et al. Accumulation of oligomer-prone α-synuclein exacerbates synaptic and neuronal degeneration in vivo. Brain. 2014;137(Pt 5):1496-513.
-
(2014)
Brain
, vol.137
, pp. 1496-1513
-
-
Rockenstein, E.1
Nuber, S.2
Overk, C.R.3
Ubhi, K.4
Mante, M.5
Patrick, C.6
-
41
-
-
27544507306
-
Α-Synuclein cooperates with CSPα in preventing neurodegeneration
-
Chandra S, Sreeganga C, Gilbert G, Rafael F-C, Schlüter OM, Südhof TC. α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration. Cell. 2005;123:383-96.
-
(2005)
Cell
, vol.123
, pp. 383-396
-
-
Chandra, S.1
Sreeganga, C.2
Gilbert, G.3
Rafael, F.-C.4
Schlüter, O.M.5
Südhof, T.C.6
-
42
-
-
77957347060
-
Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro
-
Burre J, Sharma M, Tsetsenis T, Buchman V, Etherton MR, Sudhof TC. Alpha-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro. Science. 2010;329:1663-7.
-
(2010)
Science
, vol.329
, pp. 1663-1667
-
-
Burre, J.1
Sharma, M.2
Tsetsenis, T.3
Buchman, V.4
Etherton, M.R.5
Sudhof, T.C.6
-
43
-
-
84919449363
-
Α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation
-
Burré J, Sharma M, Südhof TC. α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation. Proc Natl Acad Sci U S A. 2014;111:E4274-83.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. E4274-E4283
-
-
Burré, J.1
Sharma, M.2
Südhof, T.C.3
-
44
-
-
84929302637
-
Definition of a molecular pathway mediating -synuclein neurotoxicity
-
Burre J, Sharma M, Sudhof TC. Definition of a Molecular Pathway Mediating -Synuclein Neurotoxicity. J Neurosci. 2015;35:5221-32.
-
(2015)
J Neurosci
, vol.35
, pp. 5221-5232
-
-
Burre, J.1
Sharma, M.2
Sudhof, T.C.3
-
45
-
-
84936805775
-
Α-Synuclein interactions with phospholipid model membranes: Key roles for electrostatic interactions and lipid-bilayer structure
-
Pirc K, Ulrih NP. α-Synuclein interactions with phospholipid model membranes: Key roles for electrostatic interactions and lipid-bilayer structure. Biochim Biophys Acta. 2015;1848(10 Pt A):2002-12.
-
(2015)
Biochim Biophys Acta
, vol.1848
, Issue.10
, pp. 2002-2012
-
-
Pirc, K.1
Ulrih, N.P.2
-
46
-
-
77958482255
-
The N-terminus of the intrinsically disordered protein α-synuclein triggers membrane binding and helix folding
-
Bartels T, Tim B, Ahlstrom LS, Avigdor L, Frits K, Christian H, et al. The N-Terminus of the Intrinsically Disordered Protein α-Synuclein Triggers Membrane Binding and Helix Folding. Biophys J. 2010;99:2116-24.
-
(2010)
Biophys J
, vol.99
, pp. 2116-2124
-
-
Bartels, T.1
Tim, B.2
Ahlstrom, L.S.3
Avigdor, L.4
Frits, K.5
Christian, H.6
-
47
-
-
84936846732
-
Inhibition of amyloid-β plaque formation by α-synuclein
-
Bachhuber T, Katzmarski N, McCarter JF, Loreth D, Tahirovic S, Kamp F, et al. Inhibition of amyloid-β plaque formation by α-synuclein. Nat Med. 2015;21:802-7.
-
(2015)
Nat Med
, vol.21
, pp. 802-807
-
-
Bachhuber, T.1
Katzmarski, N.2
McCarter, J.F.3
Loreth, D.4
Tahirovic, S.5
Kamp, F.6
-
48
-
-
0037592405
-
Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas
-
Fung K-M, Rorke LB, Giasson B, Lee VM-Y, Trojanowski JQ. Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas. Acta Neuropathol. 2003;106:167-75.
-
(2003)
Acta Neuropathol
, vol.106
, pp. 167-175
-
-
Fung, K.-M.1
Rorke, L.B.2
Giasson, B.3
Lee, V.M.-Y.4
Trojanowski, J.Q.5
-
49
-
-
0034193239
-
Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary
-
Bruening W, Giasson BI, Klein-Szanto AJ, Lee VM, Trojanowski JQ, Godwin AK. Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary. Cancer. 2000;88:2154-63.
-
(2000)
Cancer
, vol.88
, pp. 2154-2163
-
-
Bruening, W.1
Giasson, B.I.2
Klein-Szanto, A.J.3
Lee, V.M.4
Trojanowski, J.Q.5
Godwin, A.K.6
-
50
-
-
84908191937
-
Analysis of alpha-synuclein in malignant melanoma - Development of a SRM quantification assay
-
Welinder C, Jönsson GB, Ingvar C, Lundgren L, Baldetorp B, Olsson H, et al. Analysis of alpha-synuclein in malignant melanoma - development of a SRM quantification assay. PLoS One. 2014;9:e110804.
-
(2014)
PLoS One
, vol.9
-
-
Welinder, C.1
Jönsson, G.B.2
Ingvar, C.3
Lundgren, L.4
Baldetorp, B.5
Olsson, H.6
-
51
-
-
84899136511
-
Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma
-
Bethge N, Lothe RA, Honne H, Andresen K, Trøen G, Eknæs M, et al. Colorectal cancer DNA methylation marker panel validated with high performance in Non-Hodgkin lymphoma. Epigenetics. 2014;9:428-36.
-
(2014)
Epigenetics
, vol.9
, pp. 428-436
-
-
Bethge, N.1
Lothe, R.A.2
Honne, H.3
Andresen, K.4
Trøen, G.5
Eknæs, M.6
-
52
-
-
33645833848
-
Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson's disease
-
El-Agnaf O, Salem SA, Paleologou KE, Curran MD. Detection of oligomeric forms of α-synuclein protein in human plasma as a potential biomarker for Parkinson's disease. FASEB J. 2006;20(3):419-25.
-
(2006)
FASEB J
, vol.20
, Issue.3
, pp. 419-425
-
-
El-Agnaf, O.1
Salem, S.A.2
Paleologou, K.E.3
Curran, M.D.4
-
53
-
-
84939232612
-
Cerebrospinal fluid alpha-synuclein as a biomarker for Parkinson's disease diagnosis: A systematic review and meta-analysis
-
Gao L, Tang H, Nie K, Wang L, Zhao J, Gan R, et al. Cerebrospinal fluid alpha-synuclein as a biomarker for Parkinson's disease diagnosis: a systematic review and meta-analysis. Int J Neurosci. 2014;125(9):645-54.
-
(2014)
Int J Neurosci
, vol.125
, Issue.9
, pp. 645-654
-
-
Gao, L.1
Tang, H.2
Nie, K.3
Wang, L.4
Zhao, J.5
Gan, R.6
-
54
-
-
84989182833
-
Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson's disease with dementia and dementia with Lewy bodies compared to
-
Hansson O, Hall S, Ohrfelt A, Zetterberg H. Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson's disease with dementia and dementia with Lewy bodies compared to. Alzheimers Res Ther. 2014;6(3):25.
-
(2014)
Alzheimers Res Ther
, vol.6
, Issue.3
, pp. 25
-
-
Hansson, O.1
Hall, S.2
Ohrfelt, A.3
Zetterberg, H.4
-
55
-
-
84876083282
-
Role of Ser129 phosphorylation of α-synuclein in melanoma cells
-
Lee BR, Matsuo Y, Cashikar AG, Kamitani T. Role of Ser129 phosphorylation of α-synuclein in melanoma cells. J Cell Sci. 2013;126(Pt 2):696-704.
-
(2013)
J Cell Sci
, vol.126
, pp. 696-704
-
-
Lee, B.R.1
Matsuo, Y.2
Cashikar, A.G.3
Kamitani, T.4
-
56
-
-
84865307818
-
Exosomal cell-to-cell transmission of alpha synuclein oligomers
-
Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, et al. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Mol Neurodegener. 2012;7:42.
-
(2012)
Mol Neurodegener
, vol.7
, pp. 42
-
-
Danzer, K.M.1
Kranich, L.R.2
Ruf, W.P.3
Cagsal-Getkin, O.4
Winslow, A.R.5
Zhu, L.6
-
57
-
-
78751703517
-
Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity
-
Lachenal G, Pernet-Gallay K, Chivet M, Hemming FJ, Belly A, Bodon G, et al. Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity. Mol Cell Neurosci. 2011;46:409-18.
-
(2011)
Mol Cell Neurosci
, vol.46
, pp. 409-418
-
-
Lachenal, G.1
Pernet-Gallay, K.2
Chivet, M.3
Hemming, F.J.4
Belly, A.5
Bodon, G.6
-
58
-
-
84928825095
-
Striatal blood-brain barrier permeability in Parkinson's disease
-
Gray MT, Woulfe JM. Striatal blood-brain barrier permeability in Parkinson's disease. J Cereb Blood Flow Metab. 2015;35:747-50.
-
(2015)
J Cereb Blood Flow Metab
, vol.35
, pp. 747-750
-
-
Gray, M.T.1
Woulfe, J.M.2
-
59
-
-
84934983329
-
Α-Synuclein strains cause distinct synucleinopathies after local and systemic administration
-
Peelaerts W, Bousset L, Van der Perren A, Moskalyuk A, Pulizzi R, Giugliano M, et al. α-Synuclein strains cause distinct synucleinopathies after local and systemic administration. Nature. 2015;522:340-4.
-
(2015)
Nature
, vol.522
, pp. 340-344
-
-
Peelaerts, W.1
Bousset, L.2
Van Der Perren, A.3
Moskalyuk, A.4
Pulizzi, R.5
Giugliano, M.6
-
60
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, et al. Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science. 2001;293:263-9.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
-
61
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura H, Hattori N, Kubo SI, Mizuno Y, Asakawa S, Minoshima S, et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet. 2000;25:302-5.
-
(2000)
Nat Genet
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.I.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
-
62
-
-
18244412384
-
Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: Evidence for variable homozygous deletions in the Parkin gene in affected individuals
-
Hattori N, Kitada T, Matsumine H, Asakawa S, Yamamura Y, Yoshino H, et al. Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals. Ann Neurol. 1998;44:935-41.
-
(1998)
Ann Neurol
, vol.44
, pp. 935-941
-
-
Hattori, N.1
Kitada, T.2
Matsumine, H.3
Asakawa, S.4
Yamamura, Y.5
Yoshino, H.6
-
63
-
-
84873453232
-
The genetics of Parkinson's disease: Progress and therapeutic implications
-
Singleton AB, Farrer MJ, Bonifati V. The genetics of Parkinson's disease: progress and therapeutic implications. Mov Disord. 2013;28:14-23.
-
(2013)
Mov Disord
, vol.28
, pp. 14-23
-
-
Singleton, A.B.1
Farrer, M.J.2
Bonifati, V.3
-
64
-
-
0342368772
-
Association between early-onset Parkinson's disease and mutations in the parkin gene
-
Lücking CB, Dürr A, Bonifati V, Vaughan J, De Michele G, Gasser T, et al. Association between Early-Onset Parkinson's Disease and Mutations in the Parkin Gene. N Engl J Med. 2000;342:1560-7.
-
(2000)
N Engl J Med
, vol.342
, pp. 1560-1567
-
-
Lücking, C.B.1
Dürr, A.2
Bonifati, V.3
Vaughan, J.4
De Michele, G.5
Gasser, T.6
-
65
-
-
0038754178
-
Parkin mutations and susceptibility alleles in late-onset Parkinson's disease
-
Oliveira SA, Scott WK, Martin ER, Nance MA, Watts RL, Hubble JP, et al. Parkin mutations and susceptibility alleles in late-onset Parkinson's disease. Ann Neurol. 2003;53:624-9.
-
(2003)
Ann Neurol
, vol.53
, pp. 624-629
-
-
Oliveira, S.A.1
Scott, W.K.2
Martin, E.R.3
Nance, M.A.4
Watts, R.L.5
Hubble, J.P.6
-
66
-
-
12244262766
-
Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease
-
Foroud T, Uniacke SK, Liu L, Pankratz N, Rudolph A, Halter C, et al. Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease. Neurology. 2003;60:796-801.
-
(2003)
Neurology
, vol.60
, pp. 796-801
-
-
Foroud, T.1
Uniacke, S.K.2
Liu, L.3
Pankratz, N.4
Rudolph, A.5
Halter, C.6
-
67
-
-
84867233572
-
Lack of association between cancer history and PARKIN genotype: A family based study in PARKIN/ Parkinson's families
-
Alcalay RN, Clark LN, Marder KS, Bradley WEC. Lack of association between cancer history and PARKIN genotype: a family based study in PARKIN/ Parkinson's families. Genes Chromosomes Cancer. 2012;51:1109-13.
-
(2012)
Genes Chromosomes Cancer
, vol.51
, pp. 1109-1113
-
-
Alcalay, R.N.1
Clark, L.N.2
Marder, K.S.3
Bradley, W.E.C.4
-
68
-
-
84931479471
-
PARK2 gene and familial lung cancer: What is the link?
-
Xiong D, Wang Y, You M. PARK2 gene and familial lung cancer: what is the link? Future Oncol. 2015;11:1707-10.
-
(2015)
Future Oncol
, vol.11
, pp. 1707-1710
-
-
Xiong, D.1
Wang, Y.2
You, M.3
-
69
-
-
73349125417
-
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies
-
Veeriah S, Taylor BS, Meng S, Fang F, Yilmaz E, Vivanco I, et al. Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. Nat Genet. 2010;42:77-82.
-
(2010)
Nat Genet
, vol.42
, pp. 77-82
-
-
Veeriah, S.1
Taylor, B.S.2
Meng, S.3
Fang, F.4
Yilmaz, E.5
Vivanco, I.6
-
71
-
-
84901616329
-
Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins
-
Gong Y, Zack TI, Morris LGT, Lin K, Hukkelhoven E, Raheja R, et al. Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins. Nat Genet. 2014;46:588-94.
-
(2014)
Nat Genet
, vol.46
, pp. 588-594
-
-
Gong, Y.1
Zack, T.I.2
Morris, L.G.T.3
Lin, K.4
Hukkelhoven, E.5
Raheja, R.6
-
72
-
-
0028909645
-
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
-
Ohtsubo M, Theodoras AM, Schumacher J, Roberts JM, Pagano M. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol. 1995;15:2612-24.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2612-2624
-
-
Ohtsubo, M.1
Theodoras, A.M.2
Schumacher, J.3
Roberts, J.M.4
Pagano, M.5
-
73
-
-
84942917216
-
Genomic and functional analysis of the E3 ligase PARK2 in glioma
-
Lin D-C, Xu L, Chen Y, Yan H, Hazawa M, Doan N, et al. Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma. Cancer Res. 2015;75:1815-27.
-
(2015)
Cancer Res
, vol.75
, pp. 1815-1827
-
-
Lin, D.-C.1
Xu, L.2
Chen, Y.3
Yan, H.4
Hazawa, M.5
Doan, N.6
-
74
-
-
0037422010
-
Parkin Is a Component of an SCF-like Ubiquitin Ligase Complex and Protects Postmitotic Neurons from Kainate Excitotoxicity
-
Staropoli JF, Caroline M, Cécile M, Brenda S, Elena D, Asa A. Parkin Is a Component of an SCF-like Ubiquitin Ligase Complex and Protects Postmitotic Neurons from Kainate Excitotoxicity. Neuron. 2003;37:735-49.
-
(2003)
Neuron
, vol.37
, pp. 735-749
-
-
Staropoli, J.F.1
Caroline, M.2
Cécile, M.3
Brenda, S.4
Elena, D.5
Asa, A.6
-
75
-
-
0033578816
-
Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1
-
Harbour JW, Luo RX, Dei Santi A, Postigo AA, Dean DC. Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1. Cell. 1999;98:859-69.
-
(1999)
Cell
, vol.98
, pp. 859-869
-
-
Harbour, J.W.1
Luo, R.X.2
Dei Santi, A.3
Postigo, A.A.4
Dean, D.C.5
-
76
-
-
84896875994
-
Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease
-
L'Episcopo F, Tirolo C, Caniglia S, Testa N, Morale MC, Serapide MF, et al. Targeting Wnt signaling at the neuroimmune interface for dopaminergic neuroprotection/repair in Parkinson's disease. J Mol Cell Biol. 2014;6:13-26.
-
(2014)
J Mol Cell Biol
, vol.6
, pp. 13-26
-
-
L'Episcopo, F.1
Tirolo, C.2
Caniglia, S.3
Testa, N.4
Morale, M.C.5
Serapide, M.F.6
-
77
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
-
Fallon L, Bélanger CML, Corera AT, Kontogiannea M, Regan-Klapisz E, Moreau F, et al. A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nat Cell Biol. 2006;8:834-42.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 834-842
-
-
Fallon, L.1
Bélanger, C.M.L.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
-
78
-
-
84930207660
-
LRRK2 pathways leading to neurodegeneration
-
Cookson MR. LRRK2 Pathways Leading to Neurodegeneration. Curr Neurol Neurosci Rep. 2015;15(7):42.
-
(2015)
Curr Neurol Neurosci Rep
, vol.15
, Issue.7
, pp. 42
-
-
Cookson, M.R.1
-
79
-
-
84918565309
-
Genetic movement disorders in patients of Jewish ancestry
-
Inzelberg R, Hassin-Baer S, Jankovic J. Genetic movement disorders in patients of Jewish ancestry. JAMA Neurol. 2014;71:1567-72.
-
(2014)
JAMA Neurol
, vol.71
, pp. 1567-1572
-
-
Inzelberg, R.1
Hassin-Baer, S.2
Jankovic, J.3
-
80
-
-
33746079596
-
A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan
-
Di Fonzo A, Yah-Huei W-C, Chin-Song L, van Doeselaar M, Simons EJ, Rohé CF, et al. A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan. Neurogenetics. 2006;7:133-8.
-
(2006)
Neurogenetics
, vol.7
, pp. 133-138
-
-
Di Fonzo, A.1
Yah-Huei, W.-C.2
Chin-Song, L.3
Van Doeselaar, M.4
Simons, E.J.5
Rohé, C.F.6
-
81
-
-
84901669528
-
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex
-
Cirnaru MD, Marte A, Belluzzi E, Russo I, Gabrielli M, Longo F, et al. LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex. Front Mol Neurosci. 2014;7:49.
-
(2014)
Front Mol Neurosci
, vol.7
, pp. 49
-
-
Cirnaru, M.D.1
Marte, A.2
Belluzzi, E.3
Russo, I.4
Gabrielli, M.5
Longo, F.6
-
82
-
-
79951534656
-
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool
-
Piccoli G, Condliffe SB, Bauer M, Giesert F, Boldt K, De Astis S, et al. LRRK2 Controls Synaptic Vesicle Storage and Mobilization within the Recycling Pool. J Neurosci. 2011;31:2225-37.
-
(2011)
J Neurosci
, vol.31
, pp. 2225-2237
-
-
Piccoli, G.1
Condliffe, S.B.2
Bauer, M.3
Giesert, F.4
Boldt, K.5
De Astis, S.6
-
83
-
-
84876981927
-
Short- and long-term effects of LRRK2 on axon and dendrite growth
-
Sepulveda B, Mesias R, Li X, Yue Z, Benson DL. Short- and long-term effects of LRRK2 on axon and dendrite growth. PLoS One. 2013;8:e61986.
-
(2013)
PLoS One
, vol.8
-
-
Sepulveda, B.1
Mesias, R.2
Li, X.3
Yue, Z.4
Benson, D.L.5
-
84
-
-
0033980068
-
Α-Synuclein is expressed in a variety of brain tumors showing neuronal differentiation
-
Kawashima M, Masatou K, Suzuki SO, Katsumi D-U, Toru I. α-Synuclein is expressed in a variety of brain tumors showing neuronal differentiation. Acta Neuropathol 2000;99:154-160.
-
(2000)
Acta Neuropathol
, vol.99
, pp. 154-160
-
-
Kawashima, M.1
Masatou, K.2
Suzuki, S.O.3
Katsumi, D.-U.4
Toru, I.5
-
85
-
-
77956674229
-
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
-
Nichols RJ, Dzamko N, Morrice NA, Campbell DG, Deak M, Ordureau A, et al. 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization. Biochem J. 2010;430:393-404.
-
(2010)
Biochem J
, vol.430
, pp. 393-404
-
-
Nichols, R.J.1
Dzamko, N.2
Morrice, N.A.3
Campbell, D.G.4
Deak, M.5
Ordureau, A.6
-
86
-
-
84975633189
-
LRRK2 promotes tau accumulation, aggregation and release
-
Epub ahead of print
-
Guerreiro PS, Ellen G, da Fonseca TL, Mathias B, Outeiro TF, Katrin E: LRRK2 Promotes Tau Accumulation, Aggregation and Release. Mol Neurobiol 2015. [Epub ahead of print]
-
(2015)
Mol Neurobiol
-
-
Guerreiro, P.S.1
Ellen, G.2
Da Fonseca, T.L.3
Mathias, B.4
Outeiro, T.F.5
Katrin, E.6
-
87
-
-
31344432937
-
LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs
-
Lesage S, Dürr A, Tazir M, Lohmann E, Leutenegger A-L, Janin S, et al. LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N Engl J Med. 2006;354:422-3.
-
(2006)
N Engl J Med
, vol.354
, pp. 422-423
-
-
Lesage, S.1
Dürr, A.2
Tazir, M.3
Lohmann, E.4
Leutenegger, A.-L.5
Janin, S.6
-
88
-
-
31344439221
-
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews
-
Ozelius LJ, Senthil G, Saunders-Pullman R, Ohmann E, Deligtisch A, Tagliati M, et al. LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med. 2006;354:424-5.
-
(2006)
N Engl J Med
, vol.354
, pp. 424-425
-
-
Ozelius, L.J.1
Senthil, G.2
Saunders-Pullman, R.3
Ohmann, E.4
Deligtisch, A.5
Tagliati, M.6
-
89
-
-
84935077167
-
LRRK2 Dephosphorylation increases its ubiquitination
-
Zhao J, Molitor TP, Langston JW, Nichols RJ. LRRK2 Dephosphorylation increases its ubiquitination. Biochem J. 2015;469(1):107-20.
-
(2015)
Biochem J
, vol.469
, Issue.1
, pp. 107-120
-
-
Zhao, J.1
Molitor, T.P.2
Langston, J.W.3
Nichols, R.J.4
-
90
-
-
84907573660
-
Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice
-
Beccano-Kelly DA, Kuhlmann N, Tatarnikov I, Volta M, Munsie LN, Chou P, et al. Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice. Front Cell Neurosci. 2014;8:301.
-
(2014)
Front Cell Neurosci
, vol.8
, pp. 301
-
-
Beccano-Kelly, D.A.1
Kuhlmann, N.2
Tatarnikov, I.3
Volta, M.4
Munsie, L.N.5
Chou, P.6
-
91
-
-
84900796431
-
Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2
-
Caesar M, Felk S, Zach S, Brønstad G, Aasly JO, Gasser T, et al. Changes in matrix metalloprotease activity and progranulin levels may contribute to the pathophysiological function of mutant leucine-rich repeat kinase 2. Glia. 2014;62:1075-92.
-
(2014)
Glia
, vol.62
, pp. 1075-1092
-
-
Caesar, M.1
Felk, S.2
Zach, S.3
Brønstad, G.4
Aasly, J.O.5
Gasser, T.6
-
92
-
-
42049087853
-
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
-
Van Damme P, Van Hoecke A, Lambrechts D, Vanacker P, Bogaert E, van Swieten J, et al. Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival. J Cell Biol. 2008;181:37-41.
-
(2008)
J Cell Biol
, vol.181
, pp. 37-41
-
-
Van Damme, P.1
Van Hoecke, A.2
Lambrechts, D.3
Vanacker, P.4
Bogaert, E.5
Van Swieten, J.6
-
93
-
-
84921415558
-
Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition
-
Hockey LN, Kilpatrick BS, Eden ER, Lin-Moshier Y, Brailoiu GC, Brailoiu E, et al. Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition. J Cell Sci. 2015;128:232-8.
-
(2015)
J Cell Sci
, vol.128
, pp. 232-238
-
-
Hockey, L.N.1
Kilpatrick, B.S.2
Eden, E.R.3
Lin-Moshier, Y.4
Brailoiu, G.C.5
Brailoiu, E.6
-
94
-
-
84936867402
-
Mutations in LRRK2 potentiate age-related impairment of autophagic flux
-
Saha S, Shamol S, Ash PEA, Vivek G, Liqun L, Orian S, et al. Mutations in LRRK2 potentiate age-related impairment of autophagic flux. Mol Neurodegener. 2015;10:26.
-
(2015)
Mol Neurodegener
, vol.10
, pp. 26
-
-
Saha, S.1
Shamol, S.2
Ash, P.E.A.3
Vivek, G.4
Liqun, L.5
Orian, S.6
-
95
-
-
79953758383
-
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2
-
Ramonet D, Daher JPL, Lin BM, Stafa K, Kim J, Banerjee R, et al. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. PLoS One. 2011;6:e18568.
-
(2011)
PLoS One
, vol.6
-
-
Ramonet, D.1
Daher, J.P.L.2
Lin, B.M.3
Stafa, K.4
Kim, J.5
Banerjee, R.6
-
96
-
-
84859929853
-
The LRRK2 G2019S mutation is associated with Parkinson disease and concomitant non-skin cancers
-
Inzelberg R, Cohen OS, Aharon-Peretz J, Schlesinger I, Gershoni-Baruch R, Djaldetti R, et al. The LRRK2 G2019S mutation is associated with Parkinson disease and concomitant non-skin cancers. Neurology. 2012;78:781-6.
-
(2012)
Neurology
, vol.78
, pp. 781-786
-
-
Inzelberg, R.1
Cohen, O.S.2
Aharon-Peretz, J.3
Schlesinger, I.4
Gershoni-Baruch, R.5
Djaldetti, R.6
-
97
-
-
84921044518
-
Higher frequency of certain cancers in LRRK2 G2019S mutation carriers with Parkinson disease: A pooled analysis
-
Agalliu I, San Luciano M, Mirelman A, Giladi N, Waro B, Aasly J, et al. Higher frequency of certain cancers in LRRK2 G2019S mutation carriers with Parkinson disease: a pooled analysis. JAMA Neurol. 2015;72:58-65.
-
(2015)
JAMA Neurol
, vol.72
, pp. 58-65
-
-
Agalliu, I.1
San Luciano, M.2
Mirelman, A.3
Giladi, N.4
Waro, B.5
Aasly, J.6
-
98
-
-
84908483784
-
LRRK2-G2019S mutation is not associated with an increased cancer risk: A kin-cohort study
-
Allegra R, Tunesi S, Cilia R, Pezzoli G, Goldwurm S. LRRK2-G2019S mutation is not associated with an increased cancer risk: A kin-cohort study. Mov Disord. 2014;29:1325-6.
-
(2014)
Mov Disord
, vol.29
, pp. 1325-1326
-
-
Allegra, R.1
Tunesi, S.2
Cilia, R.3
Pezzoli, G.4
Goldwurm, S.5
-
99
-
-
78349246706
-
LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease
-
Saunders-Pullman R, Barrett MJ, Stanley KM, Luciano MS, Shanker V, Severt L, et al. LRRK2 G2019S mutations are associated with an increased cancer risk in Parkinson disease. Mov Disord. 2010;25:2536-41.
-
(2010)
Mov Disord
, vol.25
, pp. 2536-2541
-
-
Saunders-Pullman, R.1
Barrett, M.J.2
Stanley, K.M.3
Luciano, M.S.4
Shanker, V.5
Severt, L.6
-
100
-
-
84899966492
-
Prevalence of cancer in Parkinson's disease related to R1441G and G2019S mutations in LRRK2
-
Ruiz-Martínez J, de la Riva P, Rodríguez-Oroz MC, Mondragón Rezola E, Bergareche A, Gorostidi A, et al. Prevalence of cancer in Parkinson's disease related to R1441G and G2019S mutations in LRRK2. Mov Disord. 2014;29:750-5.
-
(2014)
Mov Disord
, vol.29
, pp. 750-755
-
-
Ruiz-Martínez, J.1
De La Riva, P.2
Rodríguez-Oroz, M.C.3
Mondragón Rezola, E.4
Bergareche, A.5
Gorostidi, A.6
-
101
-
-
79960334171
-
Alpha.-Synuclein aggregation and transmission are enhanced by leucine-rich repeat kinase 2 in human neuroblastoma SH-SY5Y cells
-
Kondo K, Obitsu S, Teshima R. ALPHA.-Synuclein Aggregation and Transmission Are Enhanced by Leucine-Rich Repeat Kinase 2 in Human Neuroblastoma SH-SY5Y Cells. Biol Pharm Bull. 2011;34:1078-83.
-
(2011)
Biol Pharm Bull
, vol.34
, pp. 1078-1083
-
-
Kondo, K.1
Obitsu, S.2
Teshima, R.3
-
102
-
-
79952153682
-
Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas
-
Looyenga BD, Furge KA, Dykema KJ, Koeman J, Swiatek PJ, Giordano TJ, et al. Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas. Proc Natl Acad Sci U S A. 2011;108:1439-44.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1439-1444
-
-
Looyenga, B.D.1
Furge, K.A.2
Dykema, K.J.3
Koeman, J.4
Swiatek, P.J.5
Giordano, T.J.6
-
103
-
-
84872362045
-
The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway
-
Bravo-San Pedro JM, Niso-Santano M, Gómez-Sánchez R, Pizarro-Estrella E, Aiastui-Pujana A, Gorostidi A, et al. The LRRK2 G2019S mutant exacerbates basal autophagy through activation of the MEK/ERK pathway. Cell Mol Life Sci. 2013;70:121-36.
-
(2013)
Cell Mol Life Sci
, vol.70
, pp. 121-136
-
-
Bravo-San Pedro, J.M.1
Niso-Santano, M.2
Gómez-Sánchez, R.3
Pizarro-Estrella, E.4
Aiastui-Pujana, A.5
Gorostidi, A.6
-
104
-
-
0034966837
-
Ataxia telangiectasia: New neurons and ATM
-
McKinnon PJ. Ataxia telangiectasia: new neurons and ATM. Trends Mol Med. 2001;7:233-4.
-
(2001)
Trends Mol Med
, vol.7
, pp. 233-234
-
-
McKinnon, P.J.1
-
105
-
-
34247159940
-
Responding to DNA double strand breaks in the nervous system
-
Lee Y, McKinnon PJ. Responding to DNA double strand breaks in the nervous system. Neuroscience. 2007;145:1365-74.
-
(2007)
Neuroscience
, vol.145
, pp. 1365-1374
-
-
Lee, Y.1
McKinnon, P.J.2
-
106
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
Kastan MB, Zhan Q, El-Deiry WS, Carrier F, Jacks T, Walsh WV, et al. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell. 1992;71:587-97.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, W.V.6
-
107
-
-
0034641724
-
ATM phosphorylates Chk2 in vivo and in vitro
-
Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, Elledge SJ. ATM phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci U S A. 2000;97:10389-94.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10389-10394
-
-
Matsuoka, S.1
Rotman, G.2
Ogawa, A.3
Shiloh, Y.4
Tamai, K.5
Elledge, S.J.6
-
108
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer. 2003;3:155-68.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
109
-
-
18244385198
-
Ionizing Radiation-dependent γ-H2AX Focus Formation Requires Ataxia Telangiectasia Mutated and Ataxia Telangiectasia Mutated and Rad3-related
-
Friesner JD, Liu B, Culligan K, Britt AB. Ionizing Radiation-dependent γ-H2AX Focus Formation Requires Ataxia Telangiectasia Mutated and Ataxia Telangiectasia Mutated and Rad3-related. Mol Biol Cell. 2005;16:2566-76.
-
(2005)
Mol Biol Cell
, vol.16
, pp. 2566-2576
-
-
Friesner, J.D.1
Liu, B.2
Culligan, K.3
Britt, A.B.4
-
110
-
-
33746491583
-
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
-
Renwick A, Thompson D, Seal S, Kelly P, Chagtai T, Ahmed M, et al. ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles. Nat Genet. 2006;38:873-5.
-
(2006)
Nat Genet
, vol.38
, pp. 873-875
-
-
Renwick, A.1
Thompson, D.2
Seal, S.3
Kelly, P.4
Chagtai, T.5
Ahmed, M.6
-
112
-
-
78149467894
-
Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease
-
Camins A, Pizarro JG, Alvira D, Gutierrez-Cuesta J, de la Torre AV, Folch J, et al. Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease. Cell Mol Life Sci. 2010;67:3865-82.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3865-3882
-
-
Camins, A.1
Pizarro, J.G.2
Alvira, D.3
Gutierrez-Cuesta, J.4
De La Torre, A.V.5
Folch, J.6
-
113
-
-
84858264276
-
ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila
-
Petersen AJ, Rimkus SA, Wassarman DA. ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila. Proc Natl Acad Sci U S A. 2012;109:E656-64.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E656-E664
-
-
Petersen, A.J.1
Rimkus, S.A.2
Wassarman, D.A.3
-
114
-
-
84883072266
-
S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease
-
Sunico CR, Nakamura T, Rockenstein E, Mante M, Adame A, Chan SF, et al. S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease. Mol Neurodegener. 2013;8:29.
-
(2013)
Mol Neurodegener
, vol.8
, pp. 29
-
-
Sunico, C.R.1
Nakamura, T.2
Rockenstein, E.3
Mante, M.4
Adame, A.5
Chan, S.F.6
-
115
-
-
79960715755
-
Transcription factor p53 influences microglial activation phenotype
-
Jayadev S, Nesser NK, Hopkins S, Myers SJ, Case A, Lee RJ, et al. Transcription factor p53 influences microglial activation phenotype. Glia. 2011;59:1402-13.
-
(2011)
Glia
, vol.59
, pp. 1402-1413
-
-
Jayadev, S.1
Nesser, N.K.2
Hopkins, S.3
Myers, S.J.4
Case, A.5
Lee, R.J.6
-
116
-
-
72849131778
-
Inhibiting p53 pathways in microglia attenuates microglial-evoked neurotoxicity following exposure to Alzheimer peptides
-
Davenport CM, Sevastou IG, Hooper C, Pocock JM. Inhibiting p53 pathways in microglia attenuates microglial-evoked neurotoxicity following exposure to Alzheimer peptides. J Neurochem. 2010;112:552-63.
-
(2010)
J Neurochem
, vol.112
, pp. 552-563
-
-
Davenport, C.M.1
Sevastou, I.G.2
Hooper, C.3
Pocock, J.M.4
-
117
-
-
46749090850
-
Inhibition of p53 transcriptional activity: A potential target for future development of therapeutic strategies for primary demyelination
-
Li J, Ghiani CA, Kim JY, Liu A, Sandoval J, DeVellis J, et al. Inhibition of p53 transcriptional activity: a potential target for future development of therapeutic strategies for primary demyelination. J Neurosci. 2008;28:6118-27.
-
(2008)
J Neurosci
, vol.28
, pp. 6118-6127
-
-
Li, J.1
Ghiani, C.A.2
Kim, J.Y.3
Liu, A.4
Sandoval, J.5
DeVellis, J.6
-
118
-
-
84907707031
-
Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration
-
Jebelli J, Hooper C, Pocock JM. Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration. Neurosci Lett. 2014;583:92-7.
-
(2014)
Neurosci Lett
, vol.583
, pp. 92-97
-
-
Jebelli, J.1
Hooper, C.2
Pocock, J.M.3
-
119
-
-
84856694610
-
Emerging roles of p53 in glial cell function in health and disease
-
Jebelli JD, Hooper C, Garden GA, Pocock JM. Emerging roles of p53 in glial cell function in health and disease. Glia. 2012;60:515-25.
-
(2012)
Glia
, vol.60
, pp. 515-525
-
-
Jebelli, J.D.1
Hooper, C.2
Garden, G.A.3
Pocock, J.M.4
-
120
-
-
84866405384
-
Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1
-
Desplats P, Spencer B, Crews L, Pathel P, Morvinski-Friedmann D, Kosberg K, et al. Synuclein Induces Alterations in Adult Neurogenesis in Parkinson Disease Models via p53-mediated Repression of Notch1. J Biol Chem. 2012;287:31691-702.
-
(2012)
J Biol Chem
, vol.287
, pp. 31691-31702
-
-
Desplats, P.1
Spencer, B.2
Crews, L.3
Pathel, P.4
Morvinski-Friedmann, D.5
Kosberg, K.6
-
121
-
-
33745016466
-
The p53 family in nervous system development and disease
-
Jacobs WB, Kaplan DR, Miller FD. The p53 family in nervous system development and disease. J Neurochem. 2006;97:1571-84.
-
(2006)
J Neurochem
, vol.97
, pp. 1571-1584
-
-
Jacobs, W.B.1
Kaplan, D.R.2
Miller, F.D.3
-
122
-
-
84858970616
-
P53 at the crossroads between cancer and neurodegeneration
-
Lanni C, Racchi M, Memo M, Govoni S, Uberti D. p53 at the crossroads between cancer and neurodegeneration. Free Radic Biol Med. 2012;52:1727-33.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 1727-1733
-
-
Lanni, C.1
Racchi, M.2
Memo, M.3
Govoni, S.4
Uberti, D.5
-
123
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem. 1998;273:13375-8.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
124
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science. 1997;275:1943-7.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
-
125
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet. 1997;15:356-62.
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
-
126
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
-
Myers MP, Pass I, Batty IH, Van der Kaay J, Stolarov JP, Hemmings BA, et al. The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A. 1998;95:13513-8.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van Der Kaay, J.4
Stolarov, J.P.5
Hemmings, B.A.6
-
127
-
-
79955975429
-
Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer
-
Carver BS, Chapinski C, Wongvipat J, Hieronymus H, Chen Y, Chandarlapaty S, et al. Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. Cancer Cell. 2011;19:575-86.
-
(2011)
Cancer Cell
, vol.19
, pp. 575-586
-
-
Carver, B.S.1
Chapinski, C.2
Wongvipat, J.3
Hieronymus, H.4
Chen, Y.5
Chandarlapaty, S.6
-
128
-
-
84855985283
-
Lifetime cancer risks in individuals with germline PTEN mutations
-
Tan M-H, Mester JL, Ngeow J, Rybicki LA, Orloff MS, Eng C. Lifetime cancer risks in individuals with germline PTEN mutations. Clin Cancer Res. 2012;18:400-7.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 400-407
-
-
Tan, M.-H.1
Mester, J.L.2
Ngeow, J.3
Rybicki, L.A.4
Orloff, M.S.5
Eng, C.6
-
129
-
-
84860217431
-
The functions and regulation of the PTEN tumour suppressor
-
Song MS, Salmena L, Pandolfi PP. The functions and regulation of the PTEN tumour suppressor. Nat Rev Mol Cell Biol. 2012;13:283-96.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 283-296
-
-
Song, M.S.1
Salmena, L.2
Pandolfi, P.P.3
-
130
-
-
0034652102
-
A role for nuclear PTEN in neuronal differentiation
-
Lachyankar MB, Sultana N, Schonhoff CM, Mitra P, Poluha W, Lambert S, et al. A role for nuclear PTEN in neuronal differentiation. J Neurosci. 2000;20:1404-13.
-
(2000)
J Neurosci
, vol.20
, pp. 1404-1413
-
-
Lachyankar, M.B.1
Sultana, N.2
Schonhoff, C.M.3
Mitra, P.4
Poluha, W.5
Lambert, S.6
-
131
-
-
0033561655
-
Differential expression of MMAC/PTEN in glioblastoma multiforme: Relationship to localization and prognosis
-
Sano T, Lin H, Chen X, Langford LA, Koul D, Bondy ML, et al. Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis. Cancer Res. 1999;59:1820-4.
-
(1999)
Cancer Res
, vol.59
, pp. 1820-1824
-
-
Sano, T.1
Lin, H.2
Chen, X.3
Langford, L.A.4
Koul, D.5
Bondy, M.L.6
-
133
-
-
0035824396
-
Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo
-
Groszer M, Erickson R, Scripture-Adams DD, Lesche R, Trumpp A, Zack JA, et al. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science. 2001;294:2186-9.
-
(2001)
Science
, vol.294
, pp. 2186-2189
-
-
Groszer, M.1
Erickson, R.2
Scripture-Adams, D.D.3
Lesche, R.4
Trumpp, A.5
Zack, J.A.6
-
134
-
-
0035733762
-
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
-
Backman SA, Stambolic V, Suzuki A, Haight J, Elia A, Pretorius J, et al. Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Nat Genet. 2001;29:396-403.
-
(2001)
Nat Genet
, vol.29
, pp. 396-403
-
-
Backman, S.A.1
Stambolic, V.2
Suzuki, A.3
Haight, J.4
Elia, A.5
Pretorius, J.6
-
135
-
-
0035734381
-
Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease
-
Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, et al. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nat Genet. 2001;29:404-11.
-
(2001)
Nat Genet
, vol.29
, pp. 404-411
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Knoop, L.L.4
Tharp, R.5
Smeyne, R.J.6
-
136
-
-
55849108858
-
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway
-
Park KK, Liu K, Hu Y, Smith PD, Wang C, Cai B, et al. Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science. 2008;322:963-6.
-
(2008)
Science
, vol.322
, pp. 963-966
-
-
Park, K.K.1
Liu, K.2
Hu, Y.3
Smith, P.D.4
Wang, C.5
Cai, B.6
-
137
-
-
4344683876
-
Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development
-
Perandones C, Costanzo RV, Kowaljow V, Pivetta OH, Carminatti H, Radrizzani M. Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development. Brain Res Mol Brain Res. 2004;128:8-19.
-
(2004)
Brain Res Mol Brain Res
, vol.128
, pp. 8-19
-
-
Perandones, C.1
Costanzo, R.V.2
Kowaljow, V.3
Pivetta, O.H.4
Carminatti, H.5
Radrizzani, M.6
-
138
-
-
59749091850
-
A complex interplay between Akt, TSC2 and the two mTOR complexes
-
Huang J, Manning BD. A complex interplay between Akt, TSC2 and the two mTOR complexes. Biochem Soc Trans. 2009;37(Pt 1):217-22.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 217-222
-
-
Huang, J.1
Manning, B.D.2
-
139
-
-
75749127850
-
Rapamycin protects against neuron death in in vitro andin vivo models of Parkinson's disease
-
Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, Greene LA. Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease. J Neurosci. 2010;30:1166-75.
-
(2010)
J Neurosci
, vol.30
, pp. 1166-1175
-
-
Malagelada, C.1
Jin, Z.H.2
Jackson-Lewis, V.3
Przedborski, S.4
Greene, L.A.5
-
140
-
-
79960635284
-
Fighting neurodegeneration with rapamycin: Mechanistic insights
-
Bové J, Martínez-Vicente M, Vila M. Fighting neurodegeneration with rapamycin: mechanistic insights. Nat Rev Neurosci. 2011;12:437-52.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 437-452
-
-
Bové, J.1
Martínez-Vicente, M.2
Vila, M.3
-
141
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MMK, Harvey K, Gispert S, et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science. 2004;304:1158-60.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
-
142
-
-
10044275502
-
Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease
-
Rogaeva E, Johnson J, Lang AE, Gulick C, Gwinn-Hardy K, Kawarai T, et al. Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease. Arch Neurol. 2004;61:1898-904.
-
(2004)
Arch Neurol
, vol.61
, pp. 1898-1904
-
-
Rogaeva, E.1
Johnson, J.2
Lang, A.E.3
Gulick, C.4
Gwinn-Hardy, K.5
Kawarai, T.6
-
143
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
-
Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A, et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell. 1997;90:809-19.
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
Bonnet, H.2
Yang, A.3
Creancier, L.4
Biscan, J.C.5
Valent, A.6
-
145
-
-
84918837613
-
Functions and characteristics of PINK1 and Parkin in cancer
-
Matsuda S, Nakanishi A, Minami A, Wada Y, Kitagishi Y. Functions and characteristics of PINK1 and Parkin in cancer. Front Biosci. 2015;20:491-501.
-
(2015)
Front Biosci
, vol.20
, pp. 491-501
-
-
Matsuda, S.1
Nakanishi, A.2
Minami, A.3
Wada, Y.4
Kitagishi, Y.5
-
146
-
-
84896691095
-
The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes
-
O'Flanagan CH, Morais VA, Wurst W, De Strooper B, O'Neill C. The Parkinson's gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes. Oncogene. 2015;34:1363-74.
-
(2015)
Oncogene
, vol.34
, pp. 1363-1374
-
-
O'Flanagan, C.H.1
Morais, V.A.2
Wurst, W.3
De Strooper, B.4
O'Neill, C.5
-
148
-
-
43049148341
-
MC1R variants, melanoma and red hair color phenotype: A meta-analysis
-
Raimondi S, Sera F, Gandini S, Iodice S, Caini S, Maisonneuve P, et al. MC1R variants, melanoma and red hair color phenotype: a meta-analysis. Int J Cancer. 2008;122:2753-60.
-
(2008)
Int J Cancer
, vol.122
, pp. 2753-2760
-
-
Raimondi, S.1
Sera, F.2
Gandini, S.3
Iodice, S.4
Caini, S.5
Maisonneuve, P.6
-
149
-
-
33748920021
-
Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning
-
D'Orazio JA, Nobuhisa T, Cui R, Arya M, Spry M, Wakamatsu K, et al. Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. Nature. 2006;443:340-4.
-
(2006)
Nature
, vol.443
, pp. 340-344
-
-
D'Orazio, J.A.1
Nobuhisa, T.2
Cui, R.3
Arya, M.4
Spry, M.5
Wakamatsu, K.6
-
150
-
-
0002858431
-
A potential mechanism of local anti-inflammatory action of alpha-melanocyte-stimulating hormone within the brain: Modulation of tumor necrosis factor-alpha production by human astrocytic cells
-
Wong KY, Rajora N, Boccoli G, Catania A, Lipton JM. A potential mechanism of local anti-inflammatory action of alpha-melanocyte-stimulating hormone within the brain: modulation of tumor necrosis factor-alpha production by human astrocytic cells. Neuroimmunomodulation. 1997;4:37-41.
-
(1997)
Neuroimmunomodulation
, vol.4
, pp. 37-41
-
-
Wong, K.Y.1
Rajora, N.2
Boccoli, G.3
Catania, A.4
Lipton, J.M.5
-
152
-
-
0028885627
-
Expression of melanocortin 1 receptor in periaqueductal gray matter
-
Xia Y, Wikberg JE, Chhajlani V. Expression of melanocortin 1 receptor in periaqueductal gray matter. Neuroreport. 1995;6:2193-6.
-
(1995)
Neuroreport
, vol.6
, pp. 2193-2196
-
-
Xia, Y.1
Wikberg, J.E.2
Chhajlani, V.3
-
153
-
-
84928203520
-
The MC1R melanoma risk variant p. R160W is associated with Parkinson disease
-
Tell-Marti G, Puig-Butille JA, Potrony M, Badenas C, Mila M, Malvehy J, et al. The MC1R melanoma risk variant p. R160W is associated with Parkinson disease. Ann Neurol. 2015;77:889-94.
-
(2015)
Ann Neurol
, vol.77
, pp. 889-894
-
-
Tell-Marti, G.1
Puig-Butille, J.A.2
Potrony, M.3
Badenas, C.4
Mila, M.5
Malvehy, J.6
-
154
-
-
84903363928
-
Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease
-
e5-10
-
Dong J, Gao J, Nalls M, Gao X, Huang X, Han J, et al. Susceptibility loci for pigmentation and melanoma in relation to Parkinson's disease. Neurobiol Aging. 2014;35:1512. e5-10.
-
(2014)
Neurobiol Aging
, vol.35
, pp. 1512
-
-
Dong, J.1
Gao, J.2
Nalls, M.3
Gao, X.4
Huang, X.5
Han, J.6
-
155
-
-
75649129374
-
Cancer linked to Alzheimer disease but not vascular dementia
-
Roe CM, Fitzpatrick AL, Xiong C, Sieh W, Kuller L, Miller JP, et al. Cancer linked to Alzheimer disease but not vascular dementia. Neurology. 2010;74:106-12.
-
(2010)
Neurology
, vol.74
, pp. 106-112
-
-
Roe, C.M.1
Fitzpatrick, A.L.2
Xiong, C.3
Sieh, W.4
Kuller, L.5
Miller, J.P.6
-
156
-
-
84901952155
-
Alzheimer's disease is associated with decreased risk of cancer-specific mortality: A prospective study (NEDICES)
-
Romero JP, Benito-León J, Louis ED, Bermejo-Pareja F. Alzheimer's disease is associated with decreased risk of cancer-specific mortality: a prospective study (NEDICES). J Alzheimers Dis. 2014;40:465-73.
-
(2014)
J Alzheimers Dis
, vol.40
, pp. 465-473
-
-
Romero, J.P.1
Benito-León, J.2
Louis, E.D.3
Bermejo-Pareja, F.4
-
157
-
-
84881295894
-
Inverse occurrence of cancer and Alzheimer disease: A population-based incidence study
-
Musicco M, Adorni F, Di Santo S, Prinelli F, Pettenati C, Caltagirone C, et al. Inverse occurrence of cancer and Alzheimer disease: a population-based incidence study. Neurology. 2013;81:322-8.
-
(2013)
Neurology
, vol.81
, pp. 322-328
-
-
Musicco, M.1
Adorni, F.2
Di Santo, S.3
Prinelli, F.4
Pettenati, C.5
Caltagirone, C.6
-
158
-
-
84863933702
-
Tumor diagnosis preceding Alzheimer's disease onset: Is there a link between cancer and Alzheimer's disease?
-
Realmuto S, Cinturino A, Arnao V, Mazzola MA, Cupidi C, Aridon P, et al. Tumor diagnosis preceding Alzheimer's disease onset: is there a link between cancer and Alzheimer's disease? J Alzheimers Dis. 2012;31:177-82.
-
(2012)
J Alzheimers Dis
, vol.31
, pp. 177-182
-
-
Realmuto, S.1
Cinturino, A.2
Arnao, V.3
Mazzola, M.A.4
Cupidi, C.5
Aridon, P.6
-
159
-
-
84859192682
-
Inverse association between cancer and Alzheimer's disease: Results from the Framingham Heart Study
-
Driver JA, Beiser A, Au R, Kreger BE, Splansky GL, Kurth T, et al. Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study. BMJ. 2012;344:e1442.
-
(2012)
BMJ
, vol.344
-
-
Driver, J.A.1
Beiser, A.2
Au, R.3
Kreger, B.E.4
Splansky, G.L.5
Kurth, T.6
-
160
-
-
84879081909
-
Nonmelanoma skin cancer is associated with reduced Alzheimer disease risk
-
White RS, Lipton RB, Hall CB, Steinerman JR. Nonmelanoma skin cancer is associated with reduced Alzheimer disease risk. Neurology. 2013;80:1966-72.
-
(2013)
Neurology
, vol.80
, pp. 1966-1972
-
-
White, R.S.1
Lipton, R.B.2
Hall, C.B.3
Steinerman, J.R.4
-
161
-
-
84908455564
-
Association of cancer history with Alzheimer's disease onset and structural brain changes
-
Nudelman KNH, Risacher SL, West JD, McDonald BC, Gao S, Saykin AJ, et al. Association of cancer history with Alzheimer's disease onset and structural brain changes. Front Physiol. 2014;5:423.
-
(2014)
Front Physiol
, vol.5
, pp. 423
-
-
Nudelman, K.N.H.1
Risacher, S.L.2
West, J.D.3
McDonald, B.C.4
Gao, S.5
Saykin, A.J.6
-
162
-
-
16244391770
-
Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology
-
Griffin RJ, Moloney A, Kelliher M, Johnston JA, Ravid R, Dockery P, et al. Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology. J Neurochem. 2005;93:105-17.
-
(2005)
J Neurochem
, vol.93
, pp. 105-117
-
-
Griffin, R.J.1
Moloney, A.2
Kelliher, M.3
Johnston, J.A.4
Ravid, R.5
Dockery, P.6
-
163
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
Doble BW, Woodgett JR. GSK-3: tricks of the trade for a multi-tasking kinase. J Cell Sci. 2003;116(Pt 7):1175-86.
-
(2003)
J Cell Sci
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
164
-
-
0036759157
-
Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways
-
Stein TD, Johnson JA. Lack of neurodegeneration in transgenic mice overexpressing mutant amyloid precursor protein is associated with increased levels of transthyretin and the activation of cell survival pathways. J Neurosci. 2002;22:7380-8.
-
(2002)
J Neurosci
, vol.22
, pp. 7380-7388
-
-
Stein, T.D.1
Johnson, J.A.2
-
165
-
-
0037124108
-
Signaling Events in Amyloid β-Peptide-induced Neuronal Death and Insulin-like Growth Factor I Protection
-
Wei W, Wang X, Kusiak JW. Signaling Events in Amyloid β-Peptide-induced Neuronal Death and Insulin-like Growth Factor I Protection. J Biol Chem. 2002;277:17649-56.
-
(2002)
J Biol Chem
, vol.277
, pp. 17649-17656
-
-
Wei, W.1
Wang, X.2
Kusiak, J.W.3
-
166
-
-
77956805341
-
Comorbid cancer in Parkinson's disease
-
Lo RY, Tanner CM, Van Den Eeden SK, Albers KB, Leimpeter AD, Nelson LM. Comorbid cancer in Parkinson's disease. Mov Disord. 2010;25:1809-17.
-
(2010)
Mov Disord
, vol.25
, pp. 1809-1817
-
-
Lo, R.Y.1
Tanner, C.M.2
Van Den Eeden, S.K.3
Albers, K.B.4
Leimpeter, A.D.5
Nelson, L.M.6
-
167
-
-
76849087812
-
Cancer risk in association with Parkinson disease: A population-based study
-
Becker C, Brobert GP, Johansson S, Jick SS, Meier CR. Cancer risk in association with Parkinson disease: a population-based study. Parkinsonism Relat Disord. 2010;16:186-90.
-
(2010)
Parkinsonism Relat Disord
, vol.16
, pp. 186-190
-
-
Becker, C.1
Brobert, G.P.2
Johansson, S.3
Jick, S.S.4
Meier, C.R.5
-
168
-
-
22844448292
-
Risk of cancer after the diagnosis of Parkinson's disease: A historical cohort study
-
Elbaz A, Peterson BJ, Bower JH, Yang P, Maraganore DM, McDonnell SK, et al. Risk of cancer after the diagnosis of Parkinson's disease: a historical cohort study. Mov Disord. 2005;20:719-25.
-
(2005)
Mov Disord
, vol.20
, pp. 719-725
-
-
Elbaz, A.1
Peterson, B.J.2
Bower, J.H.3
Yang, P.4
Maraganore, D.M.5
McDonnell, S.K.6
-
169
-
-
0033933257
-
Mortality and cancer incidence in patients with Parkinson's disease
-
Minami Y, Yamamoto R, Nishikouri M, Fukao A, Hisamichi S. Mortality and cancer incidence in patients with Parkinson's disease. J Neurol. 2000;247:429-34.
-
(2000)
J Neurol
, vol.247
, pp. 429-434
-
-
Minami, Y.1
Yamamoto, R.2
Nishikouri, M.3
Fukao, A.4
Hisamichi, S.5
-
170
-
-
84894280376
-
Malignant melanoma in early-treated Parkinson's disease: The NET-PD trial
-
Constantinescu R, Elm J, Auinger P, Sharma S, Augustine EF, Khadim L, et al. Malignant melanoma in early-treated Parkinson's disease: the NET-PD trial. Mov Disord. 2014;29:263-5.
-
(2014)
Mov Disord
, vol.29
, pp. 263-265
-
-
Constantinescu, R.1
Elm, J.2
Auinger, P.3
Sharma, S.4
Augustine, E.F.5
Khadim, L.6
-
171
-
-
77749330753
-
Increased melanoma risk in Parkinson disease: A prospective clinicopathological study
-
Bertoni JM, Arlette JP, Fernandez HH, Fitzer-Attas C, Frei K, Hassan MN, et al. Increased melanoma risk in Parkinson disease: a prospective clinicopathological study. Arch Neurol. 2010;67:347-52.
-
(2010)
Arch Neurol
, vol.67
, pp. 347-352
-
-
Bertoni, J.M.1
Arlette, J.P.2
Fernandez, H.H.3
Fitzer-Attas, C.4
Frei, K.5
Hassan, M.N.6
-
172
-
-
77956859353
-
Cancer incidence in a trial of an antiapoptotic agent for Parkinson's disease
-
Schwid SR, Janice B, David O, Lynn S, Caroline T, Misser F, et al. Cancer incidence in a trial of an antiapoptotic agent for Parkinson's disease. Mov Disord. 2010;25:1801-8.
-
(2010)
Mov Disord
, vol.25
, pp. 1801-1808
-
-
Schwid, S.R.1
Janice, B.2
David, O.3
Lynn, S.4
Caroline, T.5
Misser, F.6
-
173
-
-
33846864663
-
Mortality due to amyotrophic lateral sclerosis and Parkinson's disease among melanoma patients
-
Baade PD, Fritschi L, Freedman DM. Mortality due to amyotrophic lateral sclerosis and Parkinson's disease among melanoma patients. Neuroepidemiology. 2007;28:16-20.
-
(2007)
Neuroepidemiology
, vol.28
, pp. 16-20
-
-
Baade, P.D.1
Fritschi, L.2
Freedman, D.M.3
-
174
-
-
77956134997
-
The regulation of synaptic function by α-synuclein
-
Bellani S, Sousa VL, Ronzitti G, Valtorta F, Meldolesi J, Chieregatti E. The regulation of synaptic function by α-synuclein. Commun Integr Biol. 2010;3:106-9.
-
(2010)
Commun Integr Biol
, vol.3
, pp. 106-109
-
-
Bellani, S.1
Sousa, V.L.2
Ronzitti, G.3
Valtorta, F.4
Meldolesi, J.5
Chieregatti, E.6
-
175
-
-
84885743813
-
Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model
-
Janezic S, Threlfell S, Dodson PD, Dowie MJ, Taylor TN, Potgieter D, et al. Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. Proc Natl Acad Sci U S A. 2013;110:E4016-25.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. E4016-E4025
-
-
Janezic, S.1
Threlfell, S.2
Dodson, P.D.3
Dowie, M.J.4
Taylor, T.N.5
Potgieter, D.6
-
176
-
-
79955671013
-
AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers
-
Hüls S, Högen T, Vassallo N, Danzer KM, Hengerer B, Giese A, et al. AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers. J Neurochem. 2011;117:868-78.
-
(2011)
J Neurochem
, vol.117
, pp. 868-878
-
-
Hüls, S.1
Högen, T.2
Vassallo, N.3
Danzer, K.M.4
Hengerer, B.5
Giese, A.6
-
177
-
-
33746533924
-
Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
Cooper AA. Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models. Science. 2006;313:324-8.
-
(2006)
Science
, vol.313
, pp. 324-328
-
-
Cooper, A.A.1
-
178
-
-
84865202477
-
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation
-
Diógenes MJ, Dias RB, Rombo DM, Vicente Miranda H, Maiolino F, Guerreiro P, et al. Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation. J Neurosci. 2012;32:11750-62.
-
(2012)
J Neurosci
, vol.32
, pp. 11750-11762
-
-
Diógenes, M.J.1
Dias, R.B.2
Rombo, D.M.3
Vicente Miranda, H.4
Maiolino, F.5
Guerreiro, P.6
-
179
-
-
84933538780
-
Glia and alpha-synuclein in neurodegeneration: A complex interaction
-
Epub ahead of print
-
Brück D, Wenning GK, Stefanova N, Fellner L: Glia and alpha-synuclein in neurodegeneration: A complex interaction. Neurobiol Dis 2015. [Epub ahead of print]
-
(2015)
Neurobiol Dis
-
-
Brück, D.1
Wenning, G.K.2
Stefanova, N.3
Fellner, L.4
-
180
-
-
84867280590
-
SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy
-
Sampaio-Marques B, Felgueiras C, Silva A, Rodrigues M, Tenreiro S, Franssens V, et al. SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy. 2012;8:1494-509.
-
(2012)
Autophagy
, vol.8
, pp. 1494-1509
-
-
Sampaio-Marques, B.1
Felgueiras, C.2
Silva, A.3
Rodrigues, M.4
Tenreiro, S.5
Franssens, V.6
-
181
-
-
84919339038
-
Identification of featured biomarkers in different types of lung cancer with DNA microarray
-
Zhou C, Chen H, Han L, Wang A, Chen L-A. Identification of featured biomarkers in different types of lung cancer with DNA microarray. Mol Biol Rep. 2014;41:6357-63.
-
(2014)
Mol Biol Rep
, vol.41
, pp. 6357-6363
-
-
Zhou, C.1
Chen, H.2
Han, L.3
Wang, A.4
Chen, L.-A.5
-
182
-
-
84924559742
-
Detection of SNCA and FBN1 methylation in the stool as a biomarker for colorectal cancer
-
Li W-H, Zhang H, Guo Q, Wu X-D, Xu Z-S, Dang C-X, et al. Detection of SNCA and FBN1 methylation in the stool as a biomarker for colorectal cancer. Dis Markers. 2015;2015:657570.
-
(2015)
Dis Markers
, vol.2015
, pp. 657570
-
-
Li, W.-H.1
Zhang, H.2
Guo, Q.3
Wu, X.-D.4
Xu, Z.-S.5
Dang, C.-X.6
-
183
-
-
0037592405
-
Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas
-
Fung K-M, Kar-Ming F, Rorke LB, Benoit G, Lee VM-Y, Trojanowski JQ. Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas. Acta Neuropathol. 2003;106:167-75.
-
(2003)
Acta Neuropathol
, vol.106
, pp. 167-175
-
-
Fung, K.-M.1
Kar-Ming, F.2
Rorke, L.B.3
Benoit, G.4
Lee, V.M.-Y.5
Trojanowski, J.Q.6
-
185
-
-
84905902711
-
MiR-34a is an intracellular and exosomal predictive biomarker for response to docetaxel with clinical relevance to prostate cancer progression
-
Corcoran C, Rani S, O'Driscoll L. miR-34a is an intracellular and exosomal predictive biomarker for response to docetaxel with clinical relevance to prostate cancer progression. Prostate. 2014;74:1320-34.
-
(2014)
Prostate
, vol.74
, pp. 1320-1334
-
-
Corcoran, C.1
Rani, S.2
O'Driscoll, L.3
-
186
-
-
84901669528
-
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex
-
Cirnaru MD, Marte A, Belluzzi E, Russo I, Gabrielli M, Longo F, et al. LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex. Front Mol Neurosci. 2014;7:49.
-
(2014)
Front Mol Neurosci
, vol.7
, pp. 49
-
-
Cirnaru, M.D.1
Marte, A.2
Belluzzi, E.3
Russo, I.4
Gabrielli, M.5
Longo, F.6
-
187
-
-
84875640261
-
Interplay of LRRK2 with chaperone-mediated autophagy
-
Orenstein SJ, Kuo S-H, Tasset I, Arias E, Koga H, Fernandez-Carasa I, et al. Interplay of LRRK2 with chaperone-mediated autophagy. Nat Neurosci. 2013;16:394-406.
-
(2013)
Nat Neurosci
, vol.16
, pp. 394-406
-
-
Orenstein, S.J.1
Kuo, S.-H.2
Tasset, I.3
Arias, E.4
Koga, H.5
Fernandez-Carasa, I.6
-
188
-
-
84883416205
-
The Parkinson's disease-associated LRRK2 mutation R1441G inhibits neuronal differentiation of neural stem cells
-
Bahnassawy L, Nicklas S, Palm T, Menzl I, Birzele F, Gillardon F, et al. The parkinson's disease-associated LRRK2 mutation R1441G inhibits neuronal differentiation of neural stem cells. Stem Cells Dev. 2013;22:2487-96.
-
(2013)
Stem Cells Dev
, vol.22
, pp. 2487-2496
-
-
Bahnassawy, L.1
Nicklas, S.2
Palm, T.3
Menzl, I.4
Birzele, F.5
Gillardon, F.6
-
189
-
-
59649089328
-
The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration
-
Ho CC-Y, Rideout HJ, Ribe E, Troy CM, Dauer WT. The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration. J Neurosci. 2009;29:1011-6.
-
(2009)
J Neurosci
, vol.29
, pp. 1011-1016
-
-
Ho, C.C.-Y.1
Rideout, H.J.2
Ribe, E.3
Troy, C.M.4
Dauer, W.T.5
-
190
-
-
84859259002
-
LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1
-
Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, et al. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet. 2012;21:1931-44.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 1931-1944
-
-
Wang, X.1
Yan, M.H.2
Fujioka, H.3
Liu, J.4
Wilson-Delfosse, A.5
Chen, S.G.6
-
191
-
-
84925884090
-
The role of the LRRK2 gene in Parkinsonism
-
Li J-Q, Tan L, Yu J-T. The role of the LRRK2 gene in Parkinsonism. Mol Neurodegener. 2014;9:47.
-
(2014)
Mol Neurodegener
, vol.9
, pp. 47
-
-
Li, J.-Q.1
Tan, L.2
Yu, J.-T.3
-
192
-
-
70449377127
-
Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis
-
Parisiadou L, Xie C, Cho HJ, Lin X, Gu X-L, Long C-X, et al. Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. J Neurosci. 2009;29:13971-80.
-
(2009)
J Neurosci
, vol.29
, pp. 13971-13980
-
-
Parisiadou, L.1
Xie, C.2
Cho, H.J.3
Lin, X.4
Gu, X.-L.5
Long, C.-X.6
-
193
-
-
84929353300
-
The role of α-synuclein and LRRK2 in tau phosphorylation
-
Kawakami F, Ichikawa T. The Role of α-Synuclein and LRRK2 in Tau Phosphorylation. Parkinsons Dis. 2015;2015:734746.
-
(2015)
Parkinsons Dis
, vol.2015
, pp. 734746
-
-
Kawakami, F.1
Ichikawa, T.2
-
194
-
-
77953090478
-
Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice
-
Tong Y, Yamaguchi H, Giaime E, Boyle S, Kopan R, Kelleher RJ, et al. Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of α-synuclein, and apoptotic cell death in aged mice. Proc Natl Acad Sci. 2010;107:9879-84.
-
(2010)
Proc Natl Acad Sci
, vol.107
, pp. 9879-9884
-
-
Tong, Y.1
Yamaguchi, H.2
Giaime, E.3
Boyle, S.4
Kopan, R.5
Kelleher, R.J.6
-
195
-
-
79151473945
-
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
-
Winner B, Melrose HL, Zhao C, Hinkle KM, Yue M, Kent C, et al. Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol Dis. 2011;41:706-16.
-
(2011)
Neurobiol Dis
, vol.41
, pp. 706-716
-
-
Winner, B.1
Melrose, H.L.2
Zhao, C.3
Hinkle, K.M.4
Yue, M.5
Kent, C.6
-
196
-
-
58049209715
-
Pruning and loss of excitatory synapses by the parkin ubiquitin ligase
-
Helton TD, Otsuka T, Lee M-C, Mu Y, Ehlers MD. Pruning and loss of excitatory synapses by the parkin ubiquitin ligase. Proc Natl Acad Sci U S A. 2008;105:19492-7.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19492-19497
-
-
Helton, T.D.1
Otsuka, T.2
Lee, M.-C.3
Mu, Y.4
Ehlers, M.D.5
-
197
-
-
0034700158
-
Parkin functions as an E2-dependent ubiquitin- Protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1
-
Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM. Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1. Proc Natl Acad Sci U S A. 2000;97:13354-9.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 13354-13359
-
-
Zhang, Y.1
Gao, J.2
Chung, K.K.3
Huang, H.4
Dawson, V.L.5
Dawson, T.M.6
-
198
-
-
84921369563
-
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease
-
Pickrell AM, Youle RJ. The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease. Neuron. 2015;85:257-73.
-
(2015)
Neuron
, vol.85
, pp. 257-273
-
-
Pickrell, A.M.1
Youle, R.J.2
-
199
-
-
0038732456
-
Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27
-
Cesari R, Martin ES, Calin GA, Pentimalli F, Bichi R, McAdams H, et al. Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27. Proc Natl Acad Sci U S A. 2003;100:5956-61.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5956-5961
-
-
Cesari, R.1
Martin, E.S.2
Calin, G.A.3
Pentimalli, F.4
Bichi, R.5
McAdams, H.6
-
200
-
-
84933575880
-
The organization of mitochondrial quality control and life cycle in the nervous system in vivo in the absence of PINK1
-
Devireddy S, Liu A, Lampe T, Hollenbeck PJ. The Organization of Mitochondrial Quality Control and Life Cycle in the Nervous System In Vivo in the Absence of PINK1. J Neurosci. 2015;35:9391-401.
-
(2015)
J Neurosci
, vol.35
, pp. 9391-9401
-
-
Devireddy, S.1
Liu, A.2
Lampe, T.3
Hollenbeck, P.J.4
-
201
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/ fusion machinery
-
Yang Y, Ouyang Y, Yang L, Beal MF, McQuibban A, Vogel H, et al. Pink1 regulates mitochondrial dynamics through interaction with the fission/ fusion machinery. Proc Natl Acad Sci U S A. 2008;105:7070-5.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 7070-7075
-
-
Yang, Y.1
Ouyang, Y.2
Yang, L.3
Beal, M.F.4
McQuibban, A.5
Vogel, H.6
-
202
-
-
34547489872
-
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice
-
Kitada T, Pisani A, Porter DR, Yamaguchi H, Tscherter A, Martella G, et al. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc Natl Acad Sci U S A. 2007;104:11441-6.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 11441-11446
-
-
Kitada, T.1
Pisani, A.2
Porter, D.R.3
Yamaguchi, H.4
Tscherter, A.5
Martella, G.6
-
203
-
-
84930194480
-
Parkinson's disease-associated PINK1 G309D mutation increases abnormal phosphorylation of Tau
-
Ye M, Zhou D, Zhou Y, Sun C. Parkinson's disease-associated PINK1 G309D mutation increases abnormal phosphorylation of Tau. IUBMB Life. 2015;67:286-90.
-
(2015)
IUBMB Life
, vol.67
, pp. 286-290
-
-
Ye, M.1
Zhou, D.2
Zhou, Y.3
Sun, C.4
-
204
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J, Lee SB, Lee S, Kim Y, Song S, Kim S, et al. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature. 2006;441:1157-61.
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
-
205
-
-
84861204926
-
PINK1- and Parkin-mediated mitophagy at a glance
-
Jin SM, Youle RJ. PINK1- and Parkin-mediated mitophagy at a glance. J Cell Sci. 2012;125(Pt 4):795-9.
-
(2012)
J Cell Sci
, vol.125
, pp. 795-799
-
-
Jin, S.M.1
Youle, R.J.2
-
206
-
-
78650006375
-
PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells☆
-
Berthier A, Arnaud B, Samuel N, Judit J-S, Isabel R, Francisca R, et al. PINK1 displays tissue-specific subcellular location and regulates apoptosis and cell growth in breast cancer cells☆. Hum Pathol. 2011;42:75-87.
-
(2011)
Hum Pathol
, vol.42
, pp. 75-87
-
-
Berthier, A.1
Arnaud, B.2
Samuel, N.3
Judit, J.-S.4
Isabel, R.5
Francisca, R.6
-
208
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
-
Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, Pownall S, et al. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc Natl Acad Sci U S A. 2005;102:5215-20.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
-
209
-
-
13944267769
-
DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation
-
Shendelman S, Jonason A, Martinat C, Leete T, Abeliovich A. DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation. PLoS Biol. 2004;2:e362.
-
(2004)
PLoS Biol
, vol.2
-
-
Shendelman, S.1
Jonason, A.2
Martinat, C.3
Leete, T.4
Abeliovich, A.5
-
210
-
-
84878709844
-
Neuroprotective function of DJ-1 in Parkinson's disease
-
Ariga H, Takahashi-Niki K, Kato I, Maita H, Niki T, Iguchi-Ariga SMM. Neuroprotective Function of DJ-1 in Parkinson's Disease. Oxid Med Cell Longev. 2013;2013:683920.
-
(2013)
Oxid Med Cell Longev
, vol.2013
, pp. 683920
-
-
Ariga, H.1
Takahashi-Niki, K.2
Kato, I.3
Maita, H.4
Niki, T.5
Iguchi-Ariga, S.M.M.6
-
211
-
-
59049105937
-
DJ-1/ PARK7 is an important mediator of hypoxia-induced cellular responses
-
Vasseur S, Afzal S, Tardivel-Lacombe J, Park DS, Iovanna JL, Mak TW. DJ-1/ PARK7 is an important mediator of hypoxia-induced cellular responses. Proc Natl Acad Sci U S A. 2009;106:1111-6.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 1111-1116
-
-
Vasseur, S.1
Afzal, S.2
Tardivel-Lacombe, J.3
Park, D.S.4
Iovanna, J.L.5
Mak, T.W.6
-
212
-
-
79955701611
-
DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
-
McCoy MK, Cookson MR. DJ-1 regulation of mitochondrial function and autophagy through oxidative stress. Autophagy. 2011;7:531-2.
-
(2011)
Autophagy
, vol.7
, pp. 531-532
-
-
McCoy, M.K.1
Cookson, M.R.2
-
213
-
-
13944279784
-
Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: An ES- Derived cell model of primary Parkinsonism
-
Martinat C, Shendelman S, Jonason A, Leete T, Beal MF, Yang L, et al. Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism. PLoS Biol. 2004;2, e327.
-
(2004)
PLoS Biol
, vol.2
-
-
Martinat, C.1
Shendelman, S.2
Jonason, A.3
Leete, T.4
Beal, M.F.5
Yang, L.6
-
214
-
-
70449729372
-
DJ-1 binds to mitochondrial complex I and maintains its activity
-
Hayashi T, Ishimori C, Takahashi-Niki K, Taira T, Kim Y-C, Maita H, et al. DJ-1 binds to mitochondrial complex I and maintains its activity. Biochem Biophys Res Commun. 2009;390:667-72.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 667-672
-
-
Hayashi, T.1
Ishimori, C.2
Takahashi-Niki, K.3
Taira, T.4
Kim, Y.-C.5
Maita, H.6
-
215
-
-
84885947482
-
Parkinson's disease-associated DJ-1 mutations increase abnormal phosphorylation of tau protein through Akt/GSK-3β pathways
-
Wang Y, Liu W, He X, Zhou F. Parkinson's disease-associated DJ-1 mutations increase abnormal phosphorylation of tau protein through Akt/GSK-3β pathways. J Mol Neurosci. 2013;51:911-8.
-
(2013)
J Mol Neurosci
, vol.51
, pp. 911-918
-
-
Wang, Y.1
Liu, W.2
He, X.3
Zhou, F.4
-
216
-
-
84877581963
-
DJ-1 protein expression as a predictor of pathological complete remission after neoadjuvant chemotherapy in breast cancer patients
-
Kawate T, Iwaya K, Kikuchi R, Kaise H, Oda M, Sato E, et al. DJ-1 protein expression as a predictor of pathological complete remission after neoadjuvant chemotherapy in breast cancer patients. Breast Cancer Res Treat. 2013;139:51-9.
-
(2013)
Breast Cancer Res Treat
, vol.139
, pp. 51-59
-
-
Kawate, T.1
Iwaya, K.2
Kikuchi, R.3
Kaise, H.4
Oda, M.5
Sato, E.6
-
217
-
-
79959748950
-
Proteomic analysis identified DJ-1 as a cisplatin resistant marker in non-small cell lung cancer
-
Zeng H-Z, Qu Y-Q, Zhang W-J, Xiu B, Deng A-M, Liang A-B. Proteomic analysis identified DJ-1 as a cisplatin resistant marker in non-small cell lung cancer. Int J Mol Sci. 2011;12:3489-99.
-
(2011)
Int J Mol Sci
, vol.12
, pp. 3489-3499
-
-
Zeng, H.-Z.1
Qu, Y.-Q.2
Zhang, W.-J.3
Xiu, B.4
Deng, A.-M.5
Liang, A.-B.6
-
218
-
-
79952691516
-
Serum DJ-1 as a diagnostic marker and prognostic factor for pancreatic cancer
-
He XY, Liu BY, Yao WY, Zhao XJ, Zheng Z, Li JF, et al. Serum DJ-1 as a diagnostic marker and prognostic factor for pancreatic cancer. J Dig Dis. 2011;12:131-7.
-
(2011)
J Dig Dis
, vol.12
, pp. 131-137
-
-
He, X.Y.1
Liu, B.Y.2
Yao, W.Y.3
Zhao, X.J.4
Zheng, Z.5
Li, J.F.6
-
219
-
-
84884567714
-
High-expression of DJ-1 and loss of PTEN associated with tumor metastasis and correlated with poor prognosis of gastric carcinoma
-
Li Y, Cui J, Zhang C-H, Yang D-J, Chen J-H, Zan W-H, et al. High-expression of DJ-1 and loss of PTEN associated with tumor metastasis and correlated with poor prognosis of gastric carcinoma. Int J Med Sci. 2013;10:1689-97.
-
(2013)
Int J Med Sci
, vol.10
, pp. 1689-1697
-
-
Li, Y.1
Cui, J.2
Zhang, C.-H.3
Yang, D.-J.4
Chen, J.-H.5
Zan, W.-H.6
-
220
-
-
16644381913
-
Differential control of apoptosis by DJ-1 in prostate benign and cancer cells
-
Hod Y. Differential control of apoptosis by DJ-1 in prostate benign and cancer cells. J Cell Biochem. 2004;92:1221-33.
-
(2004)
J Cell Biochem
, vol.92
, pp. 1221-1233
-
-
Hod, Y.1
-
221
-
-
0027058857
-
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau
-
Drechsel DN, Hyman AA, Cobb MH, Kirschner MW. Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau. Mol Biol Cell. 1992;3:1141-54.
-
(1992)
Mol Biol Cell
, vol.3
, pp. 1141-1154
-
-
Drechsel, D.N.1
Hyman, A.A.2
Cobb, M.H.3
Kirschner, M.W.4
-
222
-
-
84896472443
-
Tau protein modifications and interactions: Their role in function and dysfunction
-
Mietelska-Porowska A, Wasik U, Goras M, Filipek A, Niewiadomska G. Tau protein modifications and interactions: their role in function and dysfunction. Int J Mol Sci. 2014;15:4671-713.
-
(2014)
Int J Mol Sci
, vol.15
, pp. 4671-4713
-
-
Mietelska-Porowska, A.1
Wasik, U.2
Goras, M.3
Filipek, A.4
Niewiadomska, G.5
-
223
-
-
84886509822
-
A role for tau at the synapse in Alzheimer's disease pathogenesis
-
Pooler AM, Noble W, Hanger DP. A role for tau at the synapse in Alzheimer's disease pathogenesis. Neuropharmacology. 2014;76:Pt A:1-8.
-
(2014)
Neuropharmacology
, vol.76
, pp. 1-8
-
-
Pooler, A.M.1
Noble, W.2
Hanger, D.P.3
-
224
-
-
78650914558
-
Tubulin-independent tau in Alzheimer's disease and cancer: Implications for disease pathogenesis and treatment
-
Souter S, Lee G. Tubulin-independent tau in Alzheimer's disease and cancer: implications for disease pathogenesis and treatment. Curr Alzheimer Res. 2010;7:697-707.
-
(2010)
Curr Alzheimer Res
, vol.7
, pp. 697-707
-
-
Souter, S.1
Lee, G.2
-
225
-
-
20444388706
-
Microtubule-associated protein tau: A marker of paclitaxel sensitivity in breast cancer
-
Rouzier R, Rajan R, Wagner P, Hess KR, Gold DL, Stec J, et al. Microtubule-associated protein tau: a marker of paclitaxel sensitivity in breast cancer. Proc Natl Acad Sci U S A. 2005;102:8315-20.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8315-8320
-
-
Rouzier, R.1
Rajan, R.2
Wagner, P.3
Hess, K.R.4
Gold, D.L.5
Stec, J.6
-
226
-
-
84876786400
-
Tau protein as a potential predictive marker in epithelial ovarian cancer patients treated with paclitaxel/platinum first-line chemotherapy
-
Smoter M, Bodnar L, Grala B, Stec R, Zieniuk K, Kozlowski W, et al. Tau protein as a potential predictive marker in epithelial ovarian cancer patients treated with paclitaxel/platinum first-line chemotherapy. J Exp Clin Cancer Res. 2013;32:25.
-
(2013)
J Exp Clin Cancer Res
, vol.32
, pp. 25
-
-
Smoter, M.1
Bodnar, L.2
Grala, B.3
Stec, R.4
Zieniuk, K.5
Kozlowski, W.6
-
227
-
-
33746233383
-
Synapse formation and function is modulated by the amyloid precursor protein
-
Priller C, Bauer T, Mitteregger G, Krebs B, Kretzschmar HA, Herms J. Synapse formation and function is modulated by the amyloid precursor protein. J Neurosci. 2006;26:7212-21.
-
(2006)
J Neurosci
, vol.26
, pp. 7212-7221
-
-
Priller, C.1
Bauer, T.2
Mitteregger, G.3
Krebs, B.4
Kretzschmar, H.A.5
Herms, J.6
-
228
-
-
57649221135
-
Amyloid precursor protein trafficking, processing, and function
-
Thinakaran G, Koo EH. Amyloid Precursor Protein Trafficking, Processing, and Function. J Biol Chem. 2008;283:29615-9.
-
(2008)
J Biol Chem
, vol.283
, pp. 29615-29619
-
-
Thinakaran, G.1
Koo, E.H.2
-
230
-
-
12144290701
-
Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes
-
Baldus CD, Liyanarachchi S, Mrózek K, Auer H, Tanner SM, Guimond M, et al. Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes. Proc Natl Acad Sci U S A. 2004;101:3915-20.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3915-3920
-
-
Baldus, C.D.1
Liyanarachchi, S.2
Mrózek, K.3
Auer, H.4
Tanner, S.M.5
Guimond, M.6
-
231
-
-
84877591381
-
Clinical significance of amyloid precursor protein in patients with testicular germ cell tumor
-
Yamada Y, Fujimura T, Takahashi S, Takayama K, Urano T, Murata T, et al. Clinical significance of amyloid precursor protein in patients with testicular germ cell tumor. Adv Urol. 2013;2013:348438.
-
(2013)
Adv Urol
, vol.2013
, pp. 348438
-
-
Yamada, Y.1
Fujimura, T.2
Takahashi, S.3
Takayama, K.4
Urano, T.5
Murata, T.6
-
233
-
-
17644409069
-
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
-
Lee J-H, Paull TT. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science. 2005;308:551-4.
-
(2005)
Science
, vol.308
, pp. 551-554
-
-
Lee, J.-H.1
Paull, T.T.2
-
234
-
-
20544474516
-
Cancer risks and mortality in heterozygous ATM mutation carriers
-
Thompson D, Duedal S, Kirner J, McGuffog L, Last J, Reiman A, et al. Cancer risks and mortality in heterozygous ATM mutation carriers. J Natl Cancer Inst. 2005;97:813-22.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 813-822
-
-
Thompson, D.1
Duedal, S.2
Kirner, J.3
McGuffog, L.4
Last, J.5
Reiman, A.6
-
235
-
-
34447536853
-
The role of ATM in breast cancer development
-
Prokopcova J, Jana P, Zdenek K, Banwell CM, Petr P. The role of ATM in breast cancer development. Breast Cancer Res Treat. 2006;104:121-8.
-
(2006)
Breast Cancer Res Treat
, vol.104
, pp. 121-128
-
-
Prokopcova, J.1
Jana, P.2
Zdenek, K.3
Banwell, C.M.4
Petr, P.5
-
236
-
-
68149179663
-
Genome-wide association study identifies three loci associated with melanoma risk
-
Bishop DT, Demenais F, Iles MM, Harland M, Taylor JC, Corda E, et al. Genome-wide association study identifies three loci associated with melanoma risk. Nat Genet. 2009;41:920-5.
-
(2009)
Nat Genet
, vol.41
, pp. 920-925
-
-
Bishop, D.T.1
Demenais, F.2
Iles, M.M.3
Harland, M.4
Taylor, J.C.5
Corda, E.6
|