ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 11, 2012, Pages

  Petersen, Andrew J ^a   Rimkus, Stacey A ^a   Wassarman, David A ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; HU ANTIGEN; PEPTIDOGLYCAN RECOGNITION PROTEIN; TRANSCRIPTION FACTOR GAL4;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ATAXIA TELANGIECTASIA; CARBOXY TERMINAL SEQUENCE; CELL CYCLE REGULATION; CELL SURVIVAL; CONTROLLED STUDY; DNA REPAIR; DROSOPHILA; ENZYME ACTIVITY; ENZYME INHIBITION; FEMALE; GENE EXPRESSION; GENE SILENCING; GLIA CELL; IMMOBILIZATION; INNATE IMMUNITY; LONGEVITY; MALE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEMPERATURE SENSITIVITY;

ANIMALS; BRAIN; CELL CYCLE PROTEINS; CELL DEATH; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; GENE KNOCKDOWN TECHNIQUES; IMMUNITY, INNATE; LONGEVITY; NERVE DEGENERATION; NEUROGLIA; NEURONS; PROTEIN-SERINE-THREONINE KINASES; TEMPERATURE; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

ATAXIA TELANGIECTASIA;

EID: 84858264276     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1110470109     Document Type: Article

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