-
1
-
-
84892588907
-
LRRK2 phosphorylates noveltau epitopes andpromotestauopathy
-
Bailey, R. M., Covy, J. P., Melrose, H. L., Rousseau, L., Watkinson, R., Knight, J., et al. LRRK2 phosphorylates noveltau epitopes andpromotestauopathy. Acta Neuropathol. 126, 809-827. doi: 10.1007/s00401-013-1188-4
-
Acta Neuropathol
, vol.126
, pp. 809-827
-
-
Bailey, R.M.1
Covy, J.P.2
Melrose, H.L.3
Rousseau, L.4
Watkinson, R.5
Knight, J.6
-
2
-
-
41649083587
-
Dynamic and redundant regulation of LRRK2 and LRRK1 expression
-
Biskup, S., Moore, D. J., Rea, A., Lorenz-Deperieux, B., Coombes, C. E., Dawson, V. L., et al. (2007). Dynamic and redundant regulation of LRRK2 and LRRK1 expression. BMCNeurosci. 8:102. doi: 10.1186/1471-2202-8-102
-
(2007)
BMCNeurosci
, vol.8
, pp. 102
-
-
Biskup, S.1
Moore, D.J.2
Rea, A.3
Lorenz-Deperieux, B.4
Coombes, C.E.5
Dawson, V.L.6
-
3
-
-
84897401085
-
Palmitoylation of delta-catenin by DHHC5 mediates activity- induced synapse plasticity. Nat
-
Brigidi, G. S., Sun, Y., Beccano-Kelly, D., Pitman, K., Mobasser, M., Borgland, S. L., et al. (2014). Palmitoylation of delta-catenin by DHHC5 mediates activity- induced synapse plasticity. Nat. Neurosci. 17, 522-532. doi: 10.1038/nn.3657
-
(2014)
Neurosci
, vol.17
, pp. 522-532
-
-
Brigidi, G.S.1
Sun, Y.2
Beccano-Kelly, D.3
Pitman, K.4
Mobasser, M.5
Borgland, S.L.6
-
4
-
-
79955544006
-
Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2)
-
Chan, D., Citro, A., Cordy, J. M., Shen, G. C., and Wolozin, B. (2011). Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2). J. Biol. Chem. 286, 16140-16149. doi: 10.1074/jbc.M111.234005
-
(2011)
J. Biol. Chem
, vol.286
, pp. 16140-16149
-
-
Chan, D.1
Citro, A.2
Cordy, J.M.3
Shen, G.C.4
Wolozin, B.5
-
5
-
-
66549107350
-
Opposite changes in glutamatergic and GABAergic transmission underlie the diffuse hyperexcitability of synapsin I-deficient cortical networks
-
Chiappalone, M., Casagrande, S., Tedesco, M., Valtorta, F., Baldelli, P., Martinoia, S., et al. (2009). Opposite changes in glutamatergic and GABAergic transmission underlie the diffuse hyperexcitability of synapsin I-deficient cortical networks. Cereb. Cortex 19, 1422-1439. doi: 10.1093/cercor/bhn182
-
(2009)
Cereb. Cortex
, vol.19
, pp. 1422-1439
-
-
Chiappalone, M.1
Casagrande, S.2
Tedesco, M.3
Valtorta, F.4
Baldelli, P.5
Martinoia, S.6
-
6
-
-
84901669528
-
LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex
-
Cirnaru, M. D., Marte, A., Belluzzi, E., Russo, I., Gabrielli, M., Longo, F., et al. LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex. Front. Mol. Neurosci. 7:49. doi: 10.3389/fnmol.2014.00049
-
Front. Mol. Neurosci
, vol.7
, pp. 49
-
-
Cirnaru, M.D.1
Marte, A.2
Belluzzi, E.3
Russo, I.4
Gabrielli, M.5
Longo, F.6
-
7
-
-
78649389313
-
The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
-
Cookson, M. R. (2010). The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease. Nature Rev. 11, 791-797. doi: 10.1038/nrn2935
-
(2010)
Nature Rev
, vol.11
, pp. 791-797
-
-
Cookson, M.R.1
-
8
-
-
78649750585
-
A comparative study of Lrrk2 function in primary neuronal cultures
-
Dachsel, J. C., Behrouz, B., Yue, M., Beevers, J. E., Melrose, H. L., and Farrer, M. J. (2010). A comparative study of Lrrk2 function in primary neuronal cultures. Parkinsonism Relat. Disord. 16, 650-655. doi: 10.1016/j.parkreldis.2010.08.018
-
(2010)
Parkinsonism Relat. Disord
, vol.16
, pp. 650-655
-
-
Dachsel, J.C.1
Behrouz, B.2
Yue, M.3
Beevers, J.E.4
Melrose, H.L.5
Farrer, M.J.6
-
9
-
-
81555205691
-
Leucine-rich repeat kinase 2 (LRRK2) cellular biology: A review of recent advances in identifying physiological substrates and cellular functions
-
Drolet, R. E., Sanders, J. M., and Kern, J. T. (2011). Leucine-rich repeat kinase 2 (LRRK2) cellular biology: a review of recent advances in identifying physiological substrates and cellular functions. J. Neurogenet. 25, 140-151. doi: 10.3109/01677063.2011.627072
-
(2011)
J. Neurogenet
, vol.25
, pp. 140-151
-
-
Drolet, R.E.1
Sanders, J.M.2
Kern, J.T.3
-
10
-
-
35448956106
-
Vesicle pools and synapsins: New insights into old enigmas
-
Fdez, E., and Hilfiker, S. (2006). Vesicle pools and synapsins: new insights into old enigmas. Brain CellBiol. 35, 107-115. doi: 10.1007/s11068-007-9013-4
-
(2006)
Brain CellBiol
, vol.35
, pp. 107-115
-
-
Fdez, E.1
Hilfiker, S.2
-
11
-
-
80053968304
-
LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice
-
Herzig, M. C., Kolly, C., Persohn, E., Theil, D., Schweizer, T., Hafner, T., et al. LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice. Hum. Mol. Genet. 20, 4209-4223. doi: 10.1093/hmg/ddr348
-
Hum. Mol. Genet
, vol.20
, pp. 4209-4223
-
-
Herzig, M.C.1
Kolly, C.2
Persohn, E.3
Theil, D.4
Schweizer, T.5
Hafner, T.6
-
12
-
-
0037389665
-
Essential function of alpha-calcium/calmodulin-dependent protein kinase II in neurotransmitter release at a glutamatergic central synapse
-
Hinds, H. L., Goussakov, I., Nakazawa, K., Tonegawa, S., and Bolshakov, V. Y. (2003). Essential function of alpha-calcium/calmodulin-dependent protein kinase II in neurotransmitter release at a glutamatergic central synapse. Proc. Natl. Acad. Sci. U.S.A. 100, 4275-4280. doi: 10.1073/pnas.0530202100
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 4275-4280
-
-
Hinds, H.L.1
Goussakov, I.2
Nakazawa, K.3
Tonegawa, S.4
Bolshakov, V.Y.5
-
13
-
-
84861552733
-
LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors
-
Hinkle, K. M., Yue, M., Behrouz, B., Dachsel, J. C., Lincoln, S. J., Bowles, E. E., et al. (2012). LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors. Mol. Neurodegener. 7:25. doi: 10.1186/1750-1326-7-25
-
(2012)
Mol. Neurodegener
, vol.7
, pp. 25
-
-
Hinkle, K.M.1
Yue, M.2
Behrouz, B.3
Dachsel, J.C.4
Lincoln, S.J.5
Bowles, E.E.6
-
14
-
-
34548314077
-
Kinase activity is not required for alphaCaMKII- dependent presynaptic plasticity at CA3-CA1 synapses
-
Hojjati, M. R., van Woerden, G. M., Tyler, W. J., Giese, K. P., Silva, A. J., Pozzo-Miller, L., et al. (2007). Kinase activity is not required for alphaCaMKII- dependent presynaptic plasticity at CA3-CA1 synapses. Nat. Neurosci. 10, 1125-1127. doi: 10.1038/nn1946
-
(2007)
Nat. Neurosci
, vol.10
, pp. 1125-1127
-
-
Hojjati, M.R.1
Van Woerden, G.M.2
Tyler, W.J.3
Giese, K.P.4
Silva, A.J.5
Pozzo-Miller, L.6
-
15
-
-
0033213603
-
A phospho-switch controls the dynamic association ofsynapsins with synaptic vesicles
-
Hosaka, M., Hammer, R. E., and Sudhof, T. C. (1999). A phospho-switch controls the dynamic association ofsynapsins with synaptic vesicles. Neuron 24, 377-387. doi: 10.1016/S0896-6273(00)80851-X
-
(1999)
Neuron
, vol.24
, pp. 377-387
-
-
Hosaka, M.1
Hammer, R.E.2
Sudhof, T.C.3
-
16
-
-
0035887768
-
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals
-
Jovanovic, J. N., Sihra, T. S., Nairn, A. C., Hemmings, H. C. Jr., Greengard, P., and Czernik, A. J. (2001). Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals. J. Neurosci. 21, 7944-7953.
-
(2001)
J. Neurosci
, vol.21
, pp. 7944-7953
-
-
Jovanovic, J.N.1
Sihra, T.S.2
Nairn, A.C.3
Hemmings, H.C.4
Greengard, P.5
Czernik, A.J.6
-
17
-
-
84863337898
-
Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons
-
Kaufman, A. M., Milnerwood, A. J., Sepers, M. D., Coquinco, A., She, K., Wang, L., et al. (2012). Opposing roles of synaptic and extrasynaptic NMDA receptor signaling in cocultured striatal and cortical neurons. J. Neurosci. 32, 3992-4003. doi: 10.1523/JNEUROSCI.4129-11.2012
-
(2012)
J. Neurosci
, vol.32
, pp. 3992-4003
-
-
Kaufman, A.M.1
Milnerwood, A.J.2
Sepers, M.D.3
Coquinco, A.4
She, K.5
Wang, L.6
-
18
-
-
84856404449
-
LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth
-
Kawakami, F., Yabata, T., Ohta, E., Maekawa, T., Shimada, N., Suzuki, M., et al. LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth. PLoS ONE 7:e30834. doi: 10.1371/journal.pone.0030834
-
PLoS ONE
, vol.7
, pp. 30834
-
-
Kawakami, F.1
Yabata, T.2
Ohta, E.3
Maekawa, T.4
Shimada, N.5
Suzuki, M.6
-
19
-
-
34248574535
-
Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila. Biochem
-
Lee, S. B., Kim, W., Lee, S., and Chung, J. (2007). Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila. Biochem. Biophys. Res. Commun. 358, 534-539. doi: 10.1016/j.bbrc.2007.04.156
-
(2007)
Biophys. Res. Commun
, vol.358
, pp. 534-539
-
-
Lee, S.B.1
Kim, W.2
Lee, S.3
Chung, J.4
-
20
-
-
84866646876
-
The synaptic function of LRRK2
-
Lee, S., Imai, Y., Gehrke, S., Liu, S., and Lu, B. (2012). The synaptic function of LRRK2. Biochem. Soc. Trans. 40, 1047-1051. doi: 10.1042/BST20120113
-
(2012)
Biochem. Soc. Trans
, vol.40
, pp. 1047-1051
-
-
Lee, S.1
Imai, Y.2
Gehrke, S.3
Liu, S.4
Lu, B.5
-
21
-
-
78650389179
-
LRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsy- naptic compartments of the Drosophila neuromuscular junction
-
Lee, S., Liu, H. P., Lin, W. Y., Guo, H., and Lu, B. (2010). LRRK2 kinase regulates synaptic morphology through distinct substrates at the presynaptic and postsy- naptic compartments of the Drosophila neuromuscular junction. J. Neurosci. 30, 16959-16969. doi: 10.1523/JNEUROSCI.1807-10.2010
-
(2010)
J. Neurosci
, vol.30
, pp. 16959-16969
-
-
Lee, S.1
Liu, H.P.2
Lin, W.Y.3
Guo, H.4
Lu, B.5
-
22
-
-
77957377567
-
LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3ss
-
Lin, C. H., Tsai, P. I., Wu, R. M., and Chien, C. T. (2010). LRRK2 G2019S mutation induces dendrite degeneration through mislocalization and phosphorylation of tau by recruiting autoactivated GSK3ss. J. Neurosci. 30, 13138-13149. doi: 10.1523/JNEUROSCI.1737-10.2010
-
(2010)
J. Neurosci
, vol.30
, pp. 13138-13149
-
-
Lin, C.H.1
Tsai, P.I.2
Wu, R.M.3
Chien, C.T.4
-
23
-
-
84893877488
-
Phosphoproteomic evaluation of pharmacological inhibition of leucine-rich repeat kinase 2 reveals significant off-target effects of LRRK-2-IN- 1
-
Luerman, G. C., Nguyen, C., Samaroo, H., Loos, P., Xi, H., Hurtado-Lorenzo, A., et al. (2014). Phosphoproteomic evaluation of pharmacological inhibition of leucine-rich repeat kinase 2 reveals significant off-target effects of LRRK-2-IN- 1. J. Neurochem. 128, 561-576. doi: 10.1111/jnc.12483
-
(2014)
J. Neurochem
, vol.128
, pp. 561-576
-
-
Luerman, G.C.1
Nguyen, C.2
Samaroo, H.3
Loos, P.4
Xi, H.5
Hurtado-Lorenzo, A.6
-
24
-
-
33751256567
-
The familial Parkinsonism gene LRRK2 regulates neurite process morphology
-
MacLeod, D., Dowman, J., Hammond, R., Leete, T., Inoue, K., and Abeliovich, (2006). The familial Parkinsonism gene LRRK2 regulates neurite process morphology. Neuron 52, 587-593. doi: 10.1016/j.neuron.2006. 10.008
-
(2006)
Neuron
, vol.52
, pp. 587-593
-
-
Macleod, D.1
Dowman, J.2
Hammond, R.3
Leete, T.4
Inoue, K.5
Abeliovich6
-
25
-
-
67650741663
-
Network homeostasis: A matter of coordination
-
Maffei, A., and Fontanini, A. (2009). Network homeostasis: a matter of coordination. Curr. Opin. Neurobiol. 19, 168-173. doi: 10.1016/j.conb.2009. 05.012
-
(2009)
Curr. Opin. Neurobiol
, vol.19
, pp. 168-173
-
-
Maffei, A.1
Fontanini, A.2
-
26
-
-
84866510734
-
LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis
-
Matta, S., Van Kolen, K., da Cunha, R., van den Bogaart, G., Mandemakers, W., Miskiewicz, K., et al. (2012). LRRK2 controls an EndoA phosphorylation cycle in synaptic endocytosis. Neuron 75, 1008-1021. doi: 10.1016/j.neuron.2012.08.022
-
(2012)
Neuron
, vol.75
, pp. 1008-1021
-
-
Matta, S.1
Van Kolen, K.2
Da Cunha, R.3
Van Den Bogaart, G.4
Mandemakers, W.5
Miskiewicz, K.6
-
27
-
-
77957794336
-
Impaired dopaminergic neurotransmission and microtubule- associated protein tau alterations in human LRRK2 transgenic mice
-
Melrose, H. L., Dachsel, J. C., Behrouz, B., Lincoln, S. J., Yue, M., Hinkle, K. M., et al. (2010). Impaired dopaminergic neurotransmission and microtubule- associated protein tau alterations in human LRRK2 transgenic mice. Neurobiol. Dis. 40, 503-517. doi: 10.1016/j.nbd.2010.07.010
-
(2010)
Neurobiol. Dis
, vol.40
, pp. 503-517
-
-
Melrose, H.L.1
Dachsel, J.C.2
Behrouz, B.3
Lincoln, S.J.4
Yue, M.5
Hinkle, K.M.6
-
28
-
-
84863773618
-
Mitigation of augmented extrasynap- tic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington’s disease mice
-
Milnerwood, A. J., Kaufman, A. M., Sepers, M. D., Gladding, C. M., Zhang, L., Wang, L., et al. (2012). Mitigation of augmented extrasynap- tic NMDAR signaling and apoptosis in cortico-striatal co-cultures from Huntington’s disease mice. Neurobiol. Dis. 48, 40-51. doi: 10.1016/j.nbd.2012. 05.013
-
(2012)
Neurobiol. Dis
, vol.48
, pp. 40-51
-
-
Milnerwood, A.J.1
Kaufman, A.M.2
Sepers, M.D.3
Gladding, C.M.4
Zhang, L.5
Wang, L.6
-
29
-
-
84861876938
-
GTPase networks in membrane traffic
-
Mizuno-Yamasaki, E., Rivera-Molina, F., and Novick, P. (2012). GTPase networks in membrane traffic. Annu. Rev. Biochem. 81, 637-659. doi: 10.1146/annurev- biochem-052810-093700
-
(2012)
Annu. Rev. Biochem
, vol.81
, pp. 637-659
-
-
Mizuno-Yamasaki, E.1
Rivera-Molina, F.2
Novick, P.3
-
30
-
-
77956674229
-
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson’s disease-associated mutations and regulates cytoplasmic localization
-
Nichols, R. J., Dzamko, N., Morrice, N. A., Campbell, D. G., Deak, M., Ordureau, et al. (2010). 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson’s disease-associated mutations and regulates cytoplasmic localization. Biochem. J. 430, 393-404. doi: 10.1042/BJ20100483
-
(2010)
Biochem. J
, vol.430
, pp. 393-404
-
-
Nichols, R.J.1
Dzamko, N.2
Morrice, N.A.3
Campbell, D.G.4
Deak, M.5
Ordureau6
-
31
-
-
33750868447
-
Isoelectric focusing technology quantifies protein signaling in 25 cells
-
O’Neill, R. A., Bhamidipati, A., Bi, X., Deb-Basu, D., Cahill, L., Ferrante, J., et al. (2006). Isoelectric focusing technology quantifies protein signaling in 25 cells. Proc. Natl. Acad. Sci. U.S.A. 103, 16153-16158. doi: 10.1073/pnas.06079 73103
-
(2006)
Proc. Natl. Acad. Sci. U.S.A
, vol.103
, pp. 16153-16158
-
-
O’neill, R.A.1
Bhamidipati, A.2
Bi, X.3
Deb-Basu, D.4
Cahill, L.5
Ferrante, J.6
-
32
-
-
70449377127
-
Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis
-
Parisiadou, L., Xie, C., Cho, H. J., Lin, X., Gu, X. L., Long, C. X., et al. (2009). Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. J. Neurosci. 29, 13971-13980. doi: 10.1523/JNEUROSCI.3799-09.2009
-
(2009)
J. Neurosci
, vol.29
, pp. 13971-13980
-
-
Parisiadou, L.1
Xie, C.2
Cho, H.J.3
Lin, X.4
Gu, X.L.5
Long, C.X.6
-
33
-
-
84896736721
-
LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation ofPKA activity
-
Parisiadou, L., Yu, J., Sgobio, C., Xie, C., Liu, G., Sun, L., et al. (2014). LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation ofPKA activity. Nat. Neurosci. 17, 367-376. doi: 10.1038/nn.3636
-
(2014)
Nat. Neurosci
, vol.17
, pp. 367-376
-
-
Parisiadou, L.1
Yu, J.2
Sgobio, C.3
Xie, C.4
Liu, G.5
Sun, L.6
-
34
-
-
79951534656
-
LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool
-
Piccoli, G., Condliffe, S. B., Bauer, M., Giesert, F., Boldt, K., De Astis, S., et al. LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J. Neurosci. 31, 2225-2237. doi: 10.1523/JNEUROSCI.3730- 10.2011
-
J. Neurosci
, vol.31
, pp. 2225-2237
-
-
Piccoli, G.1
Condliffe, S.B.2
Bauer, M.3
Giesert, F.4
Boldt, K.5
De Astis, S.6
-
35
-
-
84901320074
-
Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated byits C-terminal WD40 domain
-
Piccoli, G., Onofri, F., Cirnaru, M. D., Kaiser, C. J., Jagtap, P., Kastenmuller, A., et al. (2014). Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated byits C-terminal WD40 domain. Mol. Cell. Biol. 34, 2147-2161. doi: 10.1128/MCB.00914-13
-
(2014)
Mol. Cell. Biol
, vol.34
, pp. 2147-2161
-
-
Piccoli, G.1
Onofri, F.2
Cirnaru, M.D.3
Kaiser, C.J.4
Jagtap, P.5
Kastenmuller, A.6
-
36
-
-
0029054397
-
Distinct pools ofsynapticvesicles in neurotransmitter release
-
Pieribone, V. A., Shupliakov, O., Brodin, L., Hilfiker-Rothenfluh, S., Czernik, A. J., and Greengard, P. (1995). Distinct pools ofsynapticvesicles in neurotransmitter release. Nature 375, 493-497. doi: 10.1038/375493a0
-
(1995)
Nature
, vol.375
, pp. 493-497
-
-
Pieribone, V.A.1
Shupliakov, O.2
Brodin, L.3
Hilfiker-Rothenfluh, S.4
Czernik, A.J.5
Greengard, P.6
-
37
-
-
39549117093
-
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
-
Plowey, E. D., Cherra, S. J. 3rd., Liu, Y. J., and Chu, C. T. (2008). Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J. Neurochem. 105, 1048-1056. doi: 10.1111/j.1471-4159.2008. 05217.x
-
(2008)
J. Neurochem
, vol.105
, pp. 1048-1056
-
-
Plowey, E.D.1
Cherra, S.J.2
Liu, Y.J.3
Chu, C.T.4
-
38
-
-
79953758383
-
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2
-
Ramonet, D., Daher, J. P., Lin, B. M., Stafa, K., Kim, J., Banerjee, R., et al. (2011). Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. PLoS ONE 6:e18568. doi: 10.1371/journal.pone.0018568
-
(2011)
PLoS ONE
, vol.6
, pp. 18568
-
-
Ramonet, D.1
Daher, J.P.2
Lin, B.M.3
Stafa, K.4
Kim, J.5
Banerjee, R.6
-
39
-
-
77956704554
-
14-3-3 proteins are promising LRRK2 interactors
-
Rudenko, I. N., and Cookson, M. R. (2010). 14-3-3 proteins are promising LRRK2 interactors. Biochem. J. 430, e5-e6. doi: 10.1042/BJ20101200
-
(2010)
Biochem. J
, vol.430
, pp. e5-e6
-
-
Rudenko, I.N.1
Cookson, M.R.2
-
40
-
-
73649120624
-
Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization
-
Sen, S., Webber, P. J., and West, A. B. (2009). Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization. J. Biol. Chem. 284, 36346-36356. doi: 10.1074/jbc.M109.025437
-
(2009)
J. Biol. Chem
, vol.284
, pp. 36346-36356
-
-
Sen, S.1
Webber, P.J.2
West, A.B.3
-
41
-
-
84876981927
-
Short- andlong- term effects of LRRK2 on axon and dendrite growth
-
Sepulveda, B., Mesias, R., Li, X., Yue, Z., and Benson, D. L. (2013). Short- andlong- term effects of LRRK2 on axon and dendrite growth. PLoS ONE 8:e61986. doi: 10.1371/journal.pone.0061986
-
(2013)
PLoS ONE
, vol.8
, pp. 61986
-
-
Sepulveda, B.1
Mesias, R.2
Li, X.3
Yue, Z.4
Benson, D.L.5
-
42
-
-
33750503402
-
Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors
-
Shepherd, J. D., Rumbaugh, G., Wu, J., Chowdhury, S., Plath, N., Kuhl, D., et al. (2006). Arc/Arg3.1 mediates homeostatic synaptic scaling of AMPA receptors. Neuron 52, 475-484. doi: 10.1016/j.neuron.2006.08.034
-
(2006)
Neuron
, vol.52
, pp. 475-484
-
-
Shepherd, J.D.1
Rumbaugh, G.2
Wu, J.3
Chowdhury, S.4
Plath, N.5
Kuhl, D.6
-
43
-
-
0026637195
-
Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice
-
Silva, A. J., Stevens, C. F., Tonegawa, S., and Wang, Y. (1992). Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science 257, 201-206. doi: 10.1126/science.1378648
-
(1992)
Science
, vol.257
, pp. 201-206
-
-
Silva, A.J.1
Stevens, C.F.2
Tonegawa, S.3
Wang, Y.4
-
44
-
-
84897586124
-
Functional interaction of Parkinson’s disease-associated LRRK2 with members of the dynamin GTPase superfamily
-
Stafa, K., Tsika, E., Moser, R., Musso, A., Glauser, L., Jones, A., et al. (2014). Functional interaction of Parkinson’s disease-associated LRRK2 with members of the dynamin GTPase superfamily. Hum. Mol. Genet. 23, 2055-2077. doi: 10.1093/hmg/ddt600
-
(2014)
Hum. Mol. Genet
, vol.23
, pp. 2055-2077
-
-
Stafa, K.1
Tsika, E.2
Moser, R.3
Musso, A.4
Glauser, L.5
Jones, A.6
-
45
-
-
2942556680
-
The synaptic vesicle cycle
-
Sudhof, T. C. (2004). The synaptic vesicle cycle. Annu. Rev. Neurosci. 27, 509-547. doi: 10.1146/annurev.neuro.26.041002.131412
-
(2004)
Annu. Rev. Neurosci
, vol.27
, pp. 509-547
-
-
Sudhof, T.C.1
-
46
-
-
79961232361
-
Progranulin deficiency decreases gross neural connectivitybutenhances transmission at individual synapses
-
Tapia, L., Milnerwood, A., Guo, A., Mills, F., Yoshida, E., Vasuta, C., et al. Progranulin deficiency decreases gross neural connectivitybutenhances transmission at individual synapses. J. Neurosci. 31, 11126-11132. doi: 10.1523/JNEUROSCI.6244-10.2011
-
J. Neurosci
, vol.31
, pp. 11126-11132
-
-
Tapia, L.1
Milnerwood, A.2
Guo, A.3
Mills, F.4
Yoshida, E.5
Vasuta, C.6
-
47
-
-
0025098982
-
Redistribution of synaptophysin and synapsin I during alpha- latrotoxin-induced release of neurotransmitter at the neuromuscular junction
-
Torri-Tarelli, F., Villa, A., Valtorta, F., De Camilli, P., Greengard, P., and Ceccarelli, (1990). Redistribution of synaptophysin and synapsin I during alpha- latrotoxin-induced release of neurotransmitter at the neuromuscular junction. J. CellBiol. 110, 449-459. doi: 10.1083/jcb.110.2.449
-
(1990)
J. CellBiol
, vol.110
, pp. 449-459
-
-
Torri-Tarelli, F.1
Villa, A.2
Valtorta, F.3
De Camilli, P.4
Greengard, P.5
Ceccarelli6
-
48
-
-
84867649477
-
Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations
-
Trancikova, A., Mamais, A., Webber, P. J., Stafa, K., Tsika, E., Glauser, L., et al. Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations. PLoS ONE 7:e47784. doi: 10.1371/journal.pone.0047784
-
PLoS ONE
, vol.7
, pp. 47784
-
-
Trancikova, A.1
Mamais, A.2
Webber, P.J.3
Stafa, K.4
Tsika, E.5
Glauser, L.6
-
49
-
-
84860123187
-
Site-specific synapsin I phosphorylation participates in the expression of post-tetanic potentiation and its enhancement by BDNF
-
Valente, P., Casagrande, S., Nieus, T., Verstegen, A. M., Valtorta, F., Benfenati, F., et al. (2012). Site-specific synapsin I phosphorylation participates in the expression of post-tetanic potentiation and its enhancement by BDNF. J. Neurosci. 32, 5868-5879. doi: 10.1523/JNEUROSCI.5275-11.2012
-
(2012)
J. Neurosci
, vol.32
, pp. 5868-5879
-
-
Valente, P.1
Casagrande, S.2
Nieus, T.3
Verstegen, A.M.4
Valtorta, F.5
Benfenati, F.6
-
50
-
-
84901019188
-
Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses
-
Verstegen, A. M., Tagliatti, E., Lignani, G., Marte, A., Stolero, T., Atias, M., et al. (2014). Phosphorylation of synapsin I by cyclin-dependent kinase-5 sets the ratio between the resting and recycling pools of synaptic vesicles at hippocampal synapses. J. Neurosci. 34, 7266-7280. doi: 10.1523/JNEUROSCI.3973- 13.2014
-
(2014)
J. Neurosci
, vol.34
, pp. 7266-7280
-
-
Verstegen, A.M.1
Tagliatti, E.2
Lignani, G.3
Marte, A.4
Stolero, T.5
Atias, M.6
-
51
-
-
84892706803
-
Inhibitoryplasticitydictates the sign ofplasticityat excitatory synapses
-
Wang, L., and Maffei, A. (2014). Inhibitoryplasticitydictates the sign ofplasticityat excitatory synapses. J. Neurosci. 34, 1083-1093. doi: 10.1523/JNEUROSCI.4711- 13.2014
-
(2014)
J. Neurosci
, vol.34
, pp. 1083-1093
-
-
Wang, L.1
Maffei, A.2
-
52
-
-
84860389765
-
Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities
-
Webber, P. J., Smith, A. D., Sen, S., Renfrow, M. B., Mobley, J. A., and West, A. (2011). Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities. J. Mol. Biol. 412, 94-110. doi: 10.1016/j.jmb.2011.07.033
-
(2011)
J. Mol. Biol
, vol.412
, pp. 94-110
-
-
Webber, P.J.1
Smith, A.D.2
Sen, S.3
Renfrow, M.B.4
Mobley, J.A.5
West, A.6
-
53
-
-
28044460070
-
Parkinson’s disease-associated mutations in leucine-rich repeat kinase augment kinase activity
-
West, A. B., Moore, D. J., Biskup, S., Bugayenko, A., Smith, W. W., Ross, C. A., et al. (2005). Parkinson’s disease-associated mutations in leucine-rich repeat kinase augment kinase activity. Proc. Natl. Acad. Sci. U.S.A. 102, 16842-16847. doi: 10.1073/pnas.0507360102
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
Ross, C.A.6
-
54
-
-
79151473945
-
Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice
-
Winner, B., Melrose, H. L., Zhao, C., Hinkle, K. M., Yue, M., Kent, C., et al. (2011). Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice. Neurobiol. Dis. 41, 706-716. doi: 10.1016/j.nbd.2010.12.008
-
(2011)
Neurobiol. Dis
, vol.41
, pp. 706-716
-
-
Winner, B.1
Melrose, H.L.2
Zhao, C.3
Hinkle, K.M.4
Yue, M.5
Kent, C.6
|