Microglial p53 activation is detrimental to neuronal synapses during activation-induced inflammation: Implications for neurodegeneration

Neuroscience Letters

Volumn 583, Issue , 2014, Pages 92-97

  Jebelli, Joseph ^a   Hooper, Claudie ^b   Pocock, Jennifer M ^c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Microglia; Neurodegeneration; P53; Synapse

Indexed keywords

CASPASE 3; DREBRIN; INTERLEUKIN 1BETA; PROTEIN P53; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; 2-PHENYLACETYLENESULFONAMIDE; BENZOTHIAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE; PIFITHRIN; SULFONAMIDE; TOLUENE;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL DIVISION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; MICROGLIA; NERVE CELL NECROSIS; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NEUROMODULATION; NEUROPATHY; NONHUMAN; PROTEIN EXPRESSION; RAT; SYNAPSE; TRANSCRIPTION INITIATION; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; BRAIN; CELL CULTURE; GENETIC TRANSCRIPTION; GENETICS; INFLAMMATION; METABOLISM; NERVE CELL; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; BENZOTHIAZOLES; BRAIN; CELLS, CULTURED; INFLAMMATION; LIPOPOLYSACCHARIDES; MICROGLIA; NEURONS; RATS, SPRAGUE-DAWLEY; SULFONAMIDES; SYNAPSES; TOLUENE; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84907707031     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.08.049     Document Type: Article

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