Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

Nature Genetics

Volumn 29, Issue 4, 2001, Pages 396-403

  Backman, Stéphanie A ^a   Stambolic, Vuk ^b   Suzuki, Akira ^c   Haight, Jillian ^b   Elia, Andrew ^b   Pretorius, James ^b   Tsao, Ming Sound ^d   Shannon, Patrick ^e   Bolon, Brad ^b   Ivy, Gwen O ^f   Mak, Tak W ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b AMGEN INC   (United States)

^c OSAKA UNIVERSITY   (Japan)

^d UNIVERSITY HEALTH NETWORK   (Canada)

^e TORONTO WESTERN HOSPITAL   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIA; BRAIN FUNCTION; CELL MUTANT; CEREBELLUM; DENTATE GYRUS; GENE DELETION; GENE MUTATION; HISTOPATHOLOGY; LHERMITTE DUCLOS DISEASE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SEIZURE; TUMOR SUPPRESSOR GENE;

ANIMALS; ATAXIA; BASE SEQUENCE; BRAIN; CELL DEATH; CELL DIVISION; CEREBELLAR DISEASES; DNA PRIMERS; GENE DELETION; GENES, TUMOR SUPPRESSOR; IMMUNOHISTOCHEMISTRY; MICE; MICE, MUTANT STRAINS; NEURONS; PHOSPHORIC MONOESTER HYDROLASES; PTEN PHOSPHOHYDROLASE; SEIZURES; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA; MAMMALIA;

EID: 0035733762     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng782     Document Type: Article

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