-
1
-
-
84961751156
-
αv Integrins combine with LC3 and atg5 to regulate toll-like receptor signalling in B cells
-
M.Acharya, A.Sokolovska, J.M.Tam, et al. (2016). αv Integrins combine with LC3 and atg5 to regulate toll-like receptor signalling in B cells. Nat Commun 7:10917.
-
(2016)
Nat Commun
, vol.7
, pp. 10917
-
-
Acharya, M.1
Sokolovska, A.2
Tam, J.M.3
-
2
-
-
85069238542
-
Mitochondria as biosynthetic factories for cancer proliferation
-
C.S.Ahn, C.M.Metallo (2015). Mitochondria as biosynthetic factories for cancer proliferation. Cancer Metab 3:1.
-
(2015)
Cancer Metab
, vol.3
, pp. 1
-
-
Ahn, C.S.1
Metallo, C.M.2
-
3
-
-
44049091757
-
Foxo1 directly regulates the transcription of recombination-activating genes during B cell development
-
R.H.Amin, M.S.Schlissel (2008). Foxo1 directly regulates the transcription of recombination-activating genes during B cell development. Nat Immunol 9:613–22.
-
(2008)
Nat Immunol
, vol.9
, pp. 613-622
-
-
Amin, R.H.1
Schlissel, M.S.2
-
4
-
-
0037342166
-
Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function
-
A.N.Anzelon, H.Wu, R.C.Rickert (2003). Pten inactivation alters peripheral B lymphocyte fate and reconstitutes CD19 function. Nat Immunol 4:287–94.
-
(2003)
Nat Immunol
, vol.4
, pp. 287-294
-
-
Anzelon, A.N.1
Wu, H.2
Rickert, R.C.3
-
5
-
-
80052774270
-
The role of mTOR inhibitors for the treatment of B-cell lymphomas
-
P.Argyriou, P.Economopoulou, S.Papageorgiou (2012). The role of mTOR inhibitors for the treatment of B-cell lymphomas. Adv Hematol 2012:435342.
-
(2012)
Adv Hematol
, vol.2012
, pp. 435342
-
-
Argyriou, P.1
Economopoulou, P.2
Papageorgiou, S.3
-
6
-
-
84963978877
-
Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses
-
J.Arnold, D.Murera, F.Arbogast, et al. (2015). Autophagy is dispensable for B-cell development but essential for humoral autoimmune responses. Cell Death Differ 23:853–64.
-
(2015)
Cell Death Differ
, vol.23
, pp. 853-864
-
-
Arnold, J.1
Murera, D.2
Arbogast, F.3
-
7
-
-
84903728178
-
PDK1 regulates B cell differentiation and homeostasis
-
G.V.Baracho, M.H.Cato, Z.Zhu, et al. (2014). PDK1 regulates B cell differentiation and homeostasis. Proc Natl Acad Sci USA 111:9573–8.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 9573-9578
-
-
Baracho, G.V.1
Cato, M.H.2
Zhu, Z.3
-
8
-
-
79953112441
-
Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation
-
G.V.Baracho, A.V.Miletic, S.A.Omori, et al. (2011). Emergence of the PI3-kinase pathway as a central modulator of normal and aberrant B cell differentiation. Curr Opin Immunol 23:178–83.
-
(2011)
Curr Opin Immunol
, vol.23
, pp. 178-183
-
-
Baracho, G.V.1
Miletic, A.V.2
Omori, S.A.3
-
9
-
-
79960724234
-
Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells
-
S.Benhamron, B.Tirosh (2011). Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells. Eur J Immunol 41:2390–6.
-
(2011)
Eur J Immunol
, vol.41
, pp. 2390-2396
-
-
Benhamron, S.1
Tirosh, B.2
-
10
-
-
84859258173
-
On the redox control of B lymphocyte differentiation and function
-
M.Bertolotti, R.Sitia, A.Rubartelli (2012). On the redox control of B lymphocyte differentiation and function. Antioxid Redox Signal 16:1139–49.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 1139-1149
-
-
Bertolotti, M.1
Sitia, R.2
Rubartelli, A.3
-
11
-
-
84863964058
-
Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma
-
A.P.Bhatt, S.R.Jacobs, A.J.Freemerman, et al. (2012). Dysregulation of fatty acid synthesis and glycolysis in non-Hodgkin lymphoma. Proc Natl Acad Sci U S A 109:11818–23.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 11818-11823
-
-
Bhatt, A.P.1
Jacobs, S.R.2
Freemerman, A.J.3
-
12
-
-
77958000904
-
The dual PI3K/mTOR inhibitor, NVP-BEZ235, is efficacious against follicular lymphoma
-
P.M.Bhende, S.I.Park, M.S.Lim, et al. (2010) The dual PI3K/mTOR inhibitor, NVP-BEZ235, is efficacious against follicular lymphoma. Leukemia 24:1781–4.
-
(2010)
Leukemia
, vol.24
, pp. 1781-1784
-
-
Bhende, P.M.1
Park, S.I.2
Lim, M.S.3
-
13
-
-
84867801805
-
Protein kinase Cbeta is critical for the metabolic switch to glycolysis following B-cell antigen receptor engagement
-
D.Blair, F.J.Dufort, T.C.Chiles (2012). Protein kinase Cbeta is critical for the metabolic switch to glycolysis following B-cell antigen receptor engagement. Biochem J 448:165–9.
-
(2012)
Biochem J
, vol.448
, pp. 165-169
-
-
Blair, D.1
Dufort, F.J.2
Chiles, T.C.3
-
14
-
-
0029831167
-
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002
-
G.J.Brunn, J.Williams, C.Sabers, et al. (1996). Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. Embo J 15:5256–67.
-
(1996)
Embo J
, vol.15
, pp. 5256-5267
-
-
Brunn, G.J.1
Williams, J.2
Sabers, C.3
-
15
-
-
34548399767
-
Cell survival under nutrient stress is dependent on metabolic conditions regulated by Akt and not by autophagic vacuoles
-
P.Bruno, A.Calastretti, M.Priulla, et al. (2007). Cell survival under nutrient stress is dependent on metabolic conditions regulated by Akt and not by autophagic vacuoles. Cell Signal 19:2118–26.
-
(2007)
Cell Signal
, vol.19
, pp. 2118-2126
-
-
Bruno, P.1
Calastretti, A.2
Priulla, M.3
-
17
-
-
20544449673
-
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation
-
M.Buzzai, D.E.Bauer, R.G.Jones, et al. (2005). The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation. Oncogene 24:4165–73.
-
(2005)
Oncogene
, vol.24
, pp. 4165-4173
-
-
Buzzai, M.1
Bauer, D.E.2
Jones, R.G.3
-
18
-
-
84867730760
-
The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers
-
D.P.Calado, Y.Sasaki, S.A.Godinho, et al. (2012). The cell-cycle regulator c-Myc is essential for the formation and maintenance of germinal centers. Nat Immunol 13:1092–100.
-
(2012)
Nat Immunol
, vol.13
, pp. 1092-1100
-
-
Calado, D.P.1
Sasaki, Y.2
Godinho, S.A.3
-
19
-
-
76949092900
-
HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species
-
M.Capasso, M.K.Bhamrah, T.Henley, et al. (2010). HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species. Nat Immunol 11:265–72.
-
(2010)
Nat Immunol
, vol.11
, pp. 265-272
-
-
Capasso, M.1
Bhamrah, M.K.2
Henley, T.3
-
20
-
-
84867595989
-
Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma
-
P.Caro, A.U.Kishan, E.Norberg, et al. (2012). Metabolic signatures uncover distinct targets in molecular subsets of diffuse large B cell lymphoma. Cancer Cell 22:547–60.
-
(2012)
Cancer Cell
, vol.22
, pp. 547-560
-
-
Caro, P.1
Kishan, A.U.2
Norberg, E.3
-
21
-
-
84898606445
-
Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells
-
A.Caro-Maldonado, R.Wang, A.G.Nichols, et al. (2014). Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol 192:3626–36.
-
(2014)
J Immunol
, vol.192
, pp. 3626-3636
-
-
Caro-Maldonado, A.1
Wang, R.2
Nichols, A.G.3
-
22
-
-
78751688466
-
Cyclin D3 is selectively required for proliferative expansion of germinal center B cells
-
M.H.Cato, S.K.Chintalapati, I.W.Yau, et al. (2011). Cyclin D3 is selectively required for proliferative expansion of germinal center B cells. Mol Cell Biol 31:127–37.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 127-137
-
-
Cato, M.H.1
Chintalapati, S.K.2
Yau, I.W.3
-
23
-
-
84902954600
-
Essential role for autophagy in the maintenance of immunological memory against influenza infection
-
M.Chen, M.J.Hong, H.Sun, et al. (2014). Essential role for autophagy in the maintenance of immunological memory against influenza infection. Nat Med 20:503–10.
-
(2014)
Nat Med
, vol.20
, pp. 503-510
-
-
Chen, M.1
Hong, M.J.2
Sun, H.3
-
24
-
-
84924546608
-
Requirement for autophagy in the long-term persistence but not initial formation of memory B cells
-
M.Chen, S.Kodali, A.Jang, et al. (2015). Requirement for autophagy in the long-term persistence but not initial formation of memory B cells. J Immunol 194:2607–15.
-
(2015)
J Immunol
, vol.194
, pp. 2607-2615
-
-
Chen, M.1
Kodali, S.2
Jang, A.3
-
25
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
C.Chen, Y.Liu, R.Liu, et al. (2008). TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med 205:2397–408.
-
(2008)
J Exp Med
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
-
26
-
-
80053158632
-
Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family
-
S.H.Cho, A.K.Ahn, P.Bhargava, et al. (2011). Glycolytic rate and lymphomagenesis depend on PARP14, an ADP ribosyltransferase of the B aggressive lymphoma (BAL) family. Proc Natl Acad Sci USA 108:15972–7.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 15972-15977
-
-
Cho, S.H.1
Ahn, A.K.2
Bhargava, P.3
-
27
-
-
84856755004
-
Phosphorylation of the insulin receptor by AMP-activated protein kinase (AMPK) promotes ligand-independent activation of the insulin signalling pathway in rodent muscle
-
I.Chopra, H.F.Li, H.Wang, K.A.Webster (2012). Phosphorylation of the insulin receptor by AMP-activated protein kinase (AMPK) promotes ligand-independent activation of the insulin signalling pathway in rodent muscle. Diabetologia 55:783–94.
-
(2012)
Diabetologia
, vol.55
, pp. 783-794
-
-
Chopra, I.1
Li, H.F.2
Wang, H.3
Webster, K.A.4
-
28
-
-
84930647059
-
TSC1 promotes B cell maturation but is dispensable for germinal center formation
-
X.Ci, M.Kuraoka, H.wang, et al. (2015). TSC1 promotes B cell maturation but is dispensable for germinal center formation. PLoS One 10:e0127527.
-
(2015)
PLoS One
, vol.10
, pp. e0127527
-
-
Ci, X.1
Kuraoka, M.2
wang, H.3
-
29
-
-
0037119630
-
A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation
-
E.Clayton, G.Bardi, S.E.Bell, et al. (2002). A crucial role for the p110delta subunit of phosphatidylinositol 3-kinase in B cell development and activation. J Exp Med 196:753–63.
-
(2002)
J Exp Med
, vol.196
, pp. 753-763
-
-
Clayton, E.1
Bardi, G.2
Bell, S.E.3
-
30
-
-
79953157651
-
Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells
-
J.L.Coloff, E.F.Mason, B.J.Altman, et al. (2011). Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells. J Biol Chem 286:5921–33.
-
(2011)
J Biol Chem
, vol.286
, pp. 5921-5933
-
-
Coloff, J.L.1
Mason, E.F.2
Altman, B.J.3
-
31
-
-
84877337315
-
ATG5 regulates plasma cell differentiation
-
K.L.Conway, P.Kuballa, B.Khor, et al. (2013). ATG5 regulates plasma cell differentiation. Autophagy 9:528–37.
-
(2013)
Autophagy
, vol.9
, pp. 528-537
-
-
Conway, K.L.1
Kuballa, P.2
Khor, B.3
-
32
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
D.A.Cross, D.R.Alessi, P.Cohen, et al. (1995). Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785–9.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
-
33
-
-
67651151038
-
Essential function for the GTPase TC21 in homeostatic antigen receptor signaling
-
P.Delgado, B.Cubelos, E.Calleja, et al. (2009). Essential function for the GTPase TC21 in homeostatic antigen receptor signaling. Nat Immunol 10:880–8.
-
(2009)
Nat Immunol
, vol.10
, pp. 880-888
-
-
Delgado, P.1
Cubelos, B.2
Calleja, E.3
-
34
-
-
56349127778
-
Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation
-
H.S.Dengler, G.V.Baracho, S.A.Omori, et al. (2008). Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation. Nat Immunol 9:1388–98.
-
(2008)
Nat Immunol
, vol.9
, pp. 1388-1398
-
-
Dengler, H.S.1
Baracho, G.V.2
Omori, S.A.3
-
35
-
-
67349280350
-
Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation
-
N.Dil, A.J.Marshall (2009). Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation. Mol Immunol 46:1970–8.
-
(2009)
Mol Immunol
, vol.46
, pp. 1970-1978
-
-
Dil, N.1
Marshall, A.J.2
-
36
-
-
0034613169
-
Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress
-
J.Ding, T.Takano, S.Gao, et al. (2000). Syk is required for the activation of Akt survival pathway in B cells exposed to oxidative stress. J Biol Chem 275:30873–7.
-
(2000)
J Biol Chem
, vol.275
, pp. 30873-30877
-
-
Ding, J.1
Takano, T.2
Gao, S.3
-
37
-
-
84963620681
-
The FOXO1 transcription factor instructs the germinal center dark zone program
-
D.Dominguez-Sola, J.Kung, A.B.Holmes, et al. (2015). The FOXO1 transcription factor instructs the germinal center dark zone program. Immunity 43:1064–74.
-
(2015)
Immunity
, vol.43
, pp. 1064-1074
-
-
Dominguez-Sola, D.1
Kung, J.2
Holmes, A.B.3
-
38
-
-
84867709361
-
The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry
-
D.Dominguez-Sola, G.D.Victora, C.Y.Ying, et al. (2012). The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry. Nat Immunol 13:1083–91.
-
(2012)
Nat Immunol
, vol.13
, pp. 1083-1091
-
-
Dominguez-Sola, D.1
Victora, G.D.2
Ying, C.Y.3
-
39
-
-
0038281331
-
Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation
-
A.C.Donahue, D.A.Fruman (2003). Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation. J Immunol 170:5851–60.
-
(2003)
J Immunol
, vol.170
, pp. 5851-5860
-
-
Donahue, A.C.1
Fruman, D.A.2
-
40
-
-
33744462050
-
Antigen receptor-mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth
-
C.A.Doughty, B.F.Bleiman, D.J.Wagner, et al. (2006). Antigen receptor-mediated changes in glucose metabolism in B lymphocytes:role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth. Blood 107:4458–65.
-
(2006)
Blood
, vol.107
, pp. 4458-4465
-
-
Doughty, C.A.1
Bleiman, B.F.2
Wagner, D.J.3
-
41
-
-
38449099803
-
Cutting edge: IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism
-
F.J.Dufort, B.F.Bleiman, M.R.Gumina, et al. (2007). Cutting edge:IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism. J Immunol 179:4953–7.
-
(2007)
J Immunol
, vol.179
, pp. 4953-4957
-
-
Dufort, F.J.1
Bleiman, B.F.2
Gumina, M.R.3
-
42
-
-
84896785783
-
Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation
-
F.J.Dufort, M.R.Gumina, N.L.Ta, et al. (2014). Glucose-dependent de novo lipogenesis in B lymphocytes:a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation. J Biol Chem 289:7011–24.
-
(2014)
J Biol Chem
, vol.289
, pp. 7011-7024
-
-
Dufort, F.J.1
Gumina, M.R.2
Ta, N.L.3
-
43
-
-
84912528393
-
mTOR and autophagy: a dynamic relationship governed by nutrients and energy
-
E.A.Dunlop, A.R.Tee (2014). mTOR and autophagy:a dynamic relationship governed by nutrients and energy. Semin Cell Dev Biol 36:121–9.
-
(2014)
Semin Cell Dev Biol
, vol.36
, pp. 121-129
-
-
Dunlop, E.A.1
Tee, A.R.2
-
44
-
-
77955483125
-
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
-
K.Duvel, J.L.Yecies, S.Menon, et al. (2010). Activation of a metabolic gene regulatory network downstream of mTOR complex 1. Mol Cell 39:171–83.
-
(2010)
Mol Cell
, vol.39
, pp. 171-183
-
-
Duvel, K.1
Yecies, J.L.2
Menon, S.3
-
45
-
-
84866758055
-
The role of FDG-PET and bone marrow examination in lymphoma staging
-
I.El-Najjar, T.Barwick, N.Avril, S.Montoto (2012). The role of FDG-PET and bone marrow examination in lymphoma staging. Ann Oncol 23:x89–91.
-
(2012)
Ann Oncol
, vol.23
, pp. x89-x91
-
-
El-Najjar, I.1
Barwick, T.2
Avril, N.3
Montoto, S.4
-
46
-
-
2542561169
-
Akt stimulates aerobic glycolysis in cancer cells
-
R.L.Elstrom, D.E.Bauer, M.Buzzai, et al. (2004). Akt stimulates aerobic glycolysis in cancer cells. Cancer Res 64:3892–9.
-
(2004)
Cancer Res
, vol.64
, pp. 3892-3899
-
-
Elstrom, R.L.1
Bauer, D.E.2
Buzzai, M.3
-
47
-
-
12944250922
-
Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A
-
X.Fang, S.X.Yu, Y.Lu, et al. (2000). Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A. Proc Natl Acad Sci USA 97:11960–5.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 11960-11965
-
-
Fang, X.1
Yu, S.X.2
Lu, Y.3
-
48
-
-
84992373341
-
Clinical development of phosphatidylinositol 3-kinase inhibitors for non-Hodgkin lymphoma
-
X.Fang, X.Zhou, X.Wang (2013). Clinical development of phosphatidylinositol 3-kinase inhibitors for non-Hodgkin lymphoma. Biomark Res 1:30.
-
(2013)
Biomark Res
, vol.1
, pp. 30
-
-
Fang, X.1
Zhou, X.2
Wang, X.3
-
49
-
-
84872159532
-
AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo
-
B.Faubert, G.Boily, S.Izreig, et al. (2013). AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo. Cell Metab 17:113–24.
-
(2013)
Cell Metab
, vol.17
, pp. 113-124
-
-
Faubert, B.1
Boily, G.2
Izreig, S.3
-
50
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
K.A.Frauwirth, J.L.Riley, M.H.Harris, et al. (2002). The CD28 signaling pathway regulates glucose metabolism. Immunity 16:769–77.
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
Riley, J.L.2
Harris, M.H.3
-
51
-
-
84857844598
-
PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic
-
D.A.Fruman, C.Rommel (2011). PI3Kδ inhibitors in cancer:rationale and serendipity merge in the clinic. Cancer Discov 1:562–72.
-
(2011)
Cancer Discov
, vol.1
, pp. 562-572
-
-
Fruman, D.A.1
Rommel, C.2
-
52
-
-
84893249799
-
PI3K and cancer: lessons, challenges and opportunities
-
D.A.Fruman, C.Rommel (2014). PI3K and cancer:lessons, challenges and opportunities. Nat Rev Drug Discov 13:140–56.
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 140-156
-
-
Fruman, D.A.1
Rommel, C.2
-
53
-
-
0030763072
-
Disruption of the Bcl6 gene results in an impaired germinal center formation
-
T.Fukuda, T.Yoshida, S.Okada, et al. (1997). Disruption of the Bcl6 gene results in an impaired germinal center formation. J Exp Med 186:439–48.
-
(1997)
J Exp Med
, vol.186
, pp. 439-448
-
-
Fukuda, T.1
Yoshida, T.2
Okada, S.3
-
54
-
-
84893746086
-
Site-specific activation of AKT protects cells from death induced by glucose deprivation
-
M.Gao, J.Liang, Y.Lu, et al. (2014). Site-specific activation of AKT protects cells from death induced by glucose deprivation. Oncogene 33:745–55.
-
(2014)
Oncogene
, vol.33
, pp. 745-755
-
-
Gao, M.1
Liang, J.2
Lu, Y.3
-
56
-
-
84920481006
-
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
-
V.A.Gerriets, R.J.Kishton, A.G.Nichols, et al. (2015). Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation. J Clin Invest 125:194–207.
-
(2015)
J Clin Invest
, vol.125
, pp. 194-207
-
-
Gerriets, V.A.1
Kishton, R.J.2
Nichols, A.G.3
-
57
-
-
84866873298
-
PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1
-
C.K.Goo, H.Y.Lim, Q.S.Ho, et al. (2012). PTEN/Akt signaling controls mitochondrial respiratory capacity through 4E-BP1. PLoS One 7:e45806.
-
(2012)
PLoS One
, vol.7
, pp. e45806
-
-
Goo, C.K.1
Lim, H.Y.2
Ho, Q.S.3
-
58
-
-
84896693794
-
PI3Kdelta inhibition by idelalisib in patients with relapsed indolent lymphoma
-
A.K.Gopal, B.S.Kahl, S.De Vos, et al. (2014). PI3Kdelta inhibition by idelalisib in patients with relapsed indolent lymphoma. N Engl J Med 370:1008–18.
-
(2014)
N Engl J Med
, vol.370
, pp. 1008-1018
-
-
Gopal, A.K.1
Kahl, B.S.2
De Vos, S.3
-
59
-
-
0034983918
-
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
-
K.Gottlob, N.Majewski, S.Kennedy, et al. (2001). Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. Genes Dev 15:1406–18.
-
(2001)
Genes Dev
, vol.15
, pp. 1406-1418
-
-
Gottlob, K.1
Majewski, N.2
Kennedy, S.3
-
60
-
-
84907212907
-
Cell biology. Metabolic control of cell death
-
D.R.Green, L.Galluzzi, G.Kroemer (2014). Cell biology. Metabolic control of cell death. Science 345:1250256.
-
(2014)
Science
, vol.345
, pp. 1250256
-
-
Green, D.R.1
Galluzzi, L.2
Kroemer, G.3
-
61
-
-
0347695988
-
Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization
-
M.A.Gregory, Y.QIY, S.R.Hann (2003). Phosphorylation by glycogen synthase kinase-3 controls c-myc proteolysis and subnuclear localization. J Biol Chem 278:51606–12.
-
(2003)
J Biol Chem
, vol.278
, pp. 51606-51612
-
-
Gregory, M.A.1
Qi, Y.2
Hann, S.R.3
-
62
-
-
0036928333
-
B cell growth is controlled by phosphatidylinosotol 3-kinase-dependent induction of Rel/NF-kappaB regulated c-myc transcription
-
R.J.Grumont, A.Strasser, S.Gerondakis (2002). B cell growth is controlled by phosphatidylinosotol 3-kinase-dependent induction of Rel/NF-kappaB regulated c-myc transcription. Mol Cell 10:1283–94.
-
(2002)
Mol Cell
, vol.10
, pp. 1283-1294
-
-
Grumont, R.J.1
Strasser, A.2
Gerondakis, S.3
-
63
-
-
23844456591
-
Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma
-
C.Gulmann, V.Espina, E.PetricoinIII, et al. (2005). Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma. Clin Cancer Res 11:5847–55.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5847-5855
-
-
Gulmann, C.1
Espina, V.2
Petricoin, E.3
-
64
-
-
42949139481
-
AMPK phosphorylation of raptor mediates a metabolic checkpoint
-
D.M.Gwinn, D.B.Shackelford, D.F.Egan, et al. (2008). AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol Cell 30:214–26.
-
(2008)
Mol Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.M.1
Shackelford, D.B.2
Egan, D.F.3
-
65
-
-
84872134358
-
GLUT1 expression patterns in different Hodgkin lymphoma subtypes and progressively transformed germinal centers
-
S.Hartmann, C.Agostinelli, J.Diener, et al. (2012). GLUT1 expression patterns in different Hodgkin lymphoma subtypes and progressively transformed germinal centers. BMC Cancer 12:586.
-
(2012)
BMC Cancer
, vol.12
, pp. 586
-
-
Hartmann, S.1
Agostinelli, C.2
Diener, J.3
-
66
-
-
77951693077
-
High immunohistochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy
-
S.Hasselblom, U.Hansson, M.Olsson, et al. (2010). High immunohistochemical expression of p-AKT predicts inferior survival in patients with diffuse large B-cell lymphoma treated with immunochemotherapy. Br J Haematol 149:560–8.
-
(2010)
Br J Haematol
, vol.149
, pp. 560-568
-
-
Hasselblom, S.1
Hansson, U.2
Olsson, M.3
-
67
-
-
77957201023
-
Phosphatidylinositol 3-kinase-delta inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals
-
S.E.Herman, A.L.Gordon, A.J.Wagner, et al. (2010). Phosphatidylinositol 3-kinase-delta inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals. Blood 116:2078–88.
-
(2010)
Blood
, vol.116
, pp. 2078-2088
-
-
Herman, S.E.1
Gordon, A.L.2
Wagner, A.J.3
-
68
-
-
84905406380
-
The impact of activated p-AKT expression on clinical outcomes in diffuse large B-cell lymphoma: a clinicopathological study of 262 cases
-
J.Y.Hong, M.E.Hong, M.K.Choi, et al. (2014). The impact of activated p-AKT expression on clinical outcomes in diffuse large B-cell lymphoma:a clinicopathological study of 262 cases. Ann Oncol 25:182–8.
-
(2014)
Ann Oncol
, vol.25
, pp. 182-188
-
-
Hong, J.Y.1
Hong, M.E.2
Choi, M.K.3
-
69
-
-
84861833364
-
mTORC1 is essential for leukemia propagation but not stem cell self-renewal
-
T.Hoshii, Y.Tadokoro, K.Naka, et al. (2012). mTORC1 is essential for leukemia propagation but not stem cell self-renewal. J Clin Invest 122:2114–29.
-
(2012)
J Clin Invest
, vol.122
, pp. 2114-2129
-
-
Hoshii, T.1
Tadokoro, Y.2
Naka, K.3
-
70
-
-
0023204258
-
Murine B-cell stimulatory factor 1 (interleukin 4) increases expression of the Fc receptor for IgE on mouse B cells
-
S.A.Hudak, S.O.Gollnick, D.H.Conrad, M.R.Kehry (1987). Murine B-cell stimulatory factor 1 (interleukin 4) increases expression of the Fc receptor for IgE on mouse B cells. Proc Natl Acad Sci USA 84:4606–10.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 4606-4610
-
-
Hudak, S.A.1
Gollnick, S.O.2
Conrad, D.H.3
Kehry, M.R.4
-
71
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
K.Inoki, Y.Li, T.Zhu, et al. (2002). TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4:648–57.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
-
72
-
-
33748153690
-
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
-
K.Inoki, H.Ouyang, T.Zhu, et al. (2006). TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. Cell 126:955–68.
-
(2006)
Cell
, vol.126
, pp. 955-968
-
-
Inoki, K.1
Ouyang, H.2
Zhu, T.3
-
73
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
K.Inoki, T.Zhu, K.L.Guan (2003). TSC2 mediates cellular energy response to control cell growth and survival. Cell 115:577–90.
-
(2003)
Cell
, vol.115
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
74
-
-
84927659377
-
Mitochondrial function provides instructive signals for activation-induced B-cell fates
-
K.J.Jang, H.Mano, K.Aoki, et al. (2015). Mitochondrial function provides instructive signals for activation-induced B-cell fates. Nat Commun 6:6750.
-
(2015)
Nat Commun
, vol.6
, pp. 6750
-
-
Jang, K.J.1
Mano, H.2
Aoki, K.3
-
75
-
-
84888438716
-
Context-specific BAFF-R signaling by the NF-κB and PI3K pathways
-
J.Jellusova, A.V.Miletic, M.CATOMH, et al. (2013). Context-specific BAFF-R signaling by the NF-κB and PI3K pathways. Cell Rep 5:1022–35.
-
(2013)
Cell Rep
, vol.5
, pp. 1022-1035
-
-
Jellusova, J.1
Miletic, A.V.2
Cato, M.3
-
76
-
-
84884676252
-
Nutrient signaling to mTOR and cell growth
-
J.L.Jewell, K.L.Guan (2013). Nutrient signaling to mTOR and cell growth. Trends Biochem Sci 38:233–42.
-
(2013)
Trends Biochem Sci
, vol.38
, pp. 233-242
-
-
Jewell, J.L.1
Guan, K.L.2
-
77
-
-
0037695593
-
Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex
-
S.T.Jou, N.Carpino, Y.Takahashi, et al. (2002). Essential, nonredundant role for the phosphoinositide 3-kinase p110delta in signaling by the B-cell receptor complex. Mol Cell Biol 22:8580–91.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 8580-8591
-
-
Jou, S.T.1
Carpino, N.2
Takahashi, Y.3
-
78
-
-
84887976550
-
The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus
-
R.Keating, T.Hertz, M.Wehenkel, et al. (2013). The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Nat Immunol 14:1266–76.
-
(2013)
Nat Immunol
, vol.14
, pp. 1266-1276
-
-
Keating, R.1
Hertz, T.2
Wehenkel, M.3
-
79
-
-
77955293654
-
Roles of GSK3 in metabolic shift toward abnormal anabolism in cell senescence
-
Y.M.Kim, Y.H.Seo, C.B.Park, et al. (2010). Roles of GSK3 in metabolic shift toward abnormal anabolism in cell senescence. Ann N Y Acad Sci 1201:65–71.
-
(2010)
Ann N Y Acad Sci
, vol.1201
, pp. 65-71
-
-
Kim, Y.M.1
Seo, Y.H.2
Park, C.B.3
-
80
-
-
84914100302
-
Glycogen synthase kinase 3 inactivation induces cell senescence through sterol regulatory element binding protein 1-mediated lipogenesis in Chang cells
-
Y.M.Kim, I.Song, Y.H.Seo, G.Yoon (2013). Glycogen synthase kinase 3 inactivation induces cell senescence through sterol regulatory element binding protein 1-mediated lipogenesis in Chang cells. Endocrinol Metab (Seoul) 28:297–308.
-
(2013)
Endocrinol Metab (Seoul)
, vol.28
, pp. 297-308
-
-
Kim, Y.M.1
Song, I.2
Seo, Y.H.3
Yoon, G.4
-
81
-
-
73949112134
-
Differentiation stage-specific requirement in hypoxia-inducible factor-1alpha-regulated glycolytic pathway during murine B cell development in bone marrow
-
H.Kojima, A.Kobayashi, D.Sakurai, et al. (2010). Differentiation stage-specific requirement in hypoxia-inducible factor-1alpha-regulated glycolytic pathway during murine B cell development in bone marrow. J Immunol 184:154–63.
-
(2010)
J Immunol
, vol.184
, pp. 154-163
-
-
Kojima, H.1
Kobayashi, A.2
Sakurai, D.3
-
82
-
-
84884568116
-
Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy
-
G.S.Krasnov, A.A.Dmitriev, V.A.Lakunina, et al. (2013). Targeting VDAC-bound hexokinase II:a promising approach for concomitant anti-cancer therapy. Expert Opin Ther Targets 17:1221–33.
-
(2013)
Expert Opin Ther Targets
, vol.17
, pp. 1221-1233
-
-
Krasnov, G.S.1
Dmitriev, A.A.2
Lakunina, V.A.3
-
83
-
-
84859778293
-
mTOR signaling in growth control and disease
-
M.Laplante, D.M.Sabatini (2012). mTOR signaling in growth control and disease. Cell 149:274–93.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
84
-
-
77955488179
-
Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells
-
A.S.Lazorchak, D.Liu, V.Facchinetti, et al. (2010). Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells. Mol Cell 39:433–43.
-
(2010)
Mol Cell
, vol.39
, pp. 433-443
-
-
Lazorchak, A.S.1
Liu, D.2
Facchinetti, V.3
-
85
-
-
84855453655
-
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells
-
A.Le, A.N.Lane, M.Hamaker, et al. (2012). Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metab 15:110–21.
-
(2012)
Cell Metab
, vol.15
, pp. 110-121
-
-
Le, A.1
Lane, A.N.2
Hamaker, M.3
-
86
-
-
84887729393
-
Requirement for Rictor in homeostasis and function of mature B lymphoid cells
-
K.Lee, L.Heffington, J.Jellusova, et al. (2013). Requirement for Rictor in homeostasis and function of mature B lymphoid cells. Blood 122:2369–79.
-
(2013)
Blood
, vol.122
, pp. 2369-2379
-
-
Lee, K.1
Heffington, L.2
Jellusova, J.3
-
87
-
-
84883416378
-
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor alpha (ERRalpha)
-
Y.Li, L.He, N.Zeng, et al. (2013). Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling regulates mitochondrial biogenesis and respiration via estrogen-related receptor alpha (ERRalpha). J Biol Chem 288:25007–24.
-
(2013)
J Biol Chem
, vol.288
, pp. 25007-25024
-
-
Li, Y.1
He, L.2
Zeng, N.3
-
88
-
-
84864296714
-
The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism
-
R.Lill, B.Hoffmann, S.Molik, et al. (2012). The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism. Biochim Biophys Acta 1823:1491–508.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 1491-1508
-
-
Lill, R.1
Hoffmann, B.2
Molik, S.3
-
89
-
-
84873702448
-
Akt and mTOR in B cell activation and differentiation
-
J.J.Limon, D.A.Fruman (2012). Akt and mTOR in B cell activation and differentiation. Front Immunol 3:228.
-
(2012)
Front Immunol
, vol.3
, pp. 228
-
-
Limon, J.J.1
Fruman, D.A.2
-
90
-
-
84913594343
-
mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition
-
J.J.Limon, L.So, S.Jellbauer, et al. (2014). mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition. Proc Natl Acad Sci USA 111:E5076–85.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E5076-E5085
-
-
Limon, J.J.1
So, L.2
Jellbauer, S.3
-
91
-
-
84926369919
-
Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis
-
T.Liu, R.J.Kishton, A.N.Macintyre, et al. (2014). Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis. Cell Death Dis 5:e1470.
-
(2014)
Cell Death Dis
, vol.5
, pp. e1470
-
-
Liu, T.1
Kishton, R.J.2
Macintyre, A.N.3
-
92
-
-
15744362289
-
Constitutive activation of GSK3 down-regulates glycogen synthase abundance and glycogen deposition in rat skeletal muscle cells
-
K.Macaulay, A.S.Blair, E.Hajduch, et al. (2005). Constitutive activation of GSK3 down-regulates glycogen synthase abundance and glycogen deposition in rat skeletal muscle cells. J Biol Chem 280:9509–18.
-
(2005)
J Biol Chem
, vol.280
, pp. 9509-9518
-
-
Macaulay, K.1
Blair, A.S.2
Hajduch, E.3
-
93
-
-
84907096988
-
Inhibition of the PI3K/Akt/mTOR signaling pathway in diffuse large B-cell lymphoma: current knowledge and clinical significance
-
A.Majchrzak, M.Witkowska, P.Smolewski (2014). Inhibition of the PI3K/Akt/mTOR signaling pathway in diffuse large B-cell lymphoma:current knowledge and clinical significance. Molecules 19:14304–15.
-
(2014)
Molecules
, vol.19
, pp. 14304-14315
-
-
Majchrzak, A.1
Witkowska, M.2
Smolewski, P.3
-
94
-
-
44849141880
-
AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function
-
A.Mayer, S.Denanglaire, B.Viollet, et al. (2008). AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function. Eur J Immunol 38:948–56.
-
(2008)
Eur J Immunol
, vol.38
, pp. 948-956
-
-
Mayer, A.1
Denanglaire, S.2
Viollet, B.3
-
95
-
-
84861215287
-
Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy
-
S.K.Mcbrayer, J.C.Cheng, S.Singhal, et al. (2012). Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11:implications for glucose transporter-directed therapy. Blood 119:4686–97.
-
(2012)
Blood
, vol.119
, pp. 4686-4697
-
-
Mcbrayer, S.K.1
Cheng, J.C.2
Singhal, S.3
-
96
-
-
84923070858
-
Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders
-
N.P.Mena, P.J.Urrutia, F.Lourido, et al. (2015). Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders. Mitochondrion 21:92–105.
-
(2015)
Mitochondrion
, vol.21
, pp. 92-105
-
-
Mena, N.P.1
Urrutia, P.J.2
Lourido, F.3
-
97
-
-
79953172571
-
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
R.D.Michalek, V.A.Gerriets, S.R.Jacobs, et al. (2011a). Cutting edge:distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. J Immunol 186:3299–303.
-
(2011)
J Immunol
, vol.186
, pp. 3299-3303
-
-
Michalek, R.D.1
Gerriets, V.A.2
Jacobs, S.R.3
-
98
-
-
81055126129
-
Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation
-
R.D.Michalek, V.A.Gerriets, A.G.Nichols, et al. (2011b). Estrogen-related receptor-α is a metabolic regulator of effector T-cell activation and differentiation. Proc Natl Acad Sci USA 108:18348–53.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 18348-18353
-
-
Michalek, R.D.1
Gerriets, V.A.2
Nichols, A.G.3
-
99
-
-
41449106674
-
The autophagy gene ATG5 plays an essential role in B lymphocyte development
-
B.C.Miller, Z.Zhao, L.M.Stephenson, et al. (2008). The autophagy gene ATG5 plays an essential role in B lymphocyte development. Autophagy 4:309–14.
-
(2008)
Autophagy
, vol.4
, pp. 309-314
-
-
Miller, B.C.1
Zhao, Z.2
Stephenson, L.M.3
-
101
-
-
70349687405
-
Discovery of Atg5/Atg7-independent alternative macroautophagy
-
Y.Nishida, S.Arakawa, K.Fujitani, et al. (2009). Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature 461:654–8.
-
(2009)
Nature
, vol.461
, pp. 654-658
-
-
Nishida, Y.1
Arakawa, S.2
Fujitani, K.3
-
102
-
-
56849118516
-
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis
-
V.Nogueira, Y.Park, C.C.Chen, et al. (2008). Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. Cancer Cell 14:458–70.
-
(2008)
Cancer Cell
, vol.14
, pp. 458-470
-
-
Nogueira, V.1
Park, Y.2
Chen, C.C.3
-
103
-
-
2342459790
-
DNA damage-induced apoptosis
-
C.J.Norbury, B.Zhivotovsky (2004). DNA damage-induced apoptosis. Oncogene 23:2797–808.
-
(2004)
Oncogene
, vol.23
, pp. 2797-2808
-
-
Norbury, C.J.1
Zhivotovsky, B.2
-
104
-
-
84911132031
-
Bcl-6 directly represses the gene program of the glycolysis pathway
-
K.J.Oestreich, K.A.Read, S.E.Gilbertson, et al. (2014). Bcl-6 directly represses the gene program of the glycolysis pathway. Nat Immunol 15:957–64.
-
(2014)
Nat Immunol
, vol.15
, pp. 957-964
-
-
Oestreich, K.J.1
Read, K.A.2
Gilbertson, S.E.3
-
105
-
-
79960470913
-
mTOR complex 2 signaling and functions
-
W.J.Oh, E.Jacinto (2011). mTOR complex 2 signaling and functions. Cell Cycle 10:2305–16.
-
(2011)
Cell Cycle
, vol.10
, pp. 2305-2316
-
-
Oh, W.J.1
Jacinto, E.2
-
106
-
-
0034507903
-
BCAP: the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation
-
T.Okada, A.Maeda, A.Iwamatsu, et al. (2000). BCAP:the tyrosine kinase substrate that connects B cell receptor to phosphoinositide 3-kinase activation. Immunity 13:817–27.
-
(2000)
Immunity
, vol.13
, pp. 817-827
-
-
Okada, T.1
Maeda, A.2
Iwamatsu, A.3
-
107
-
-
33749685322
-
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling
-
S.A.Omori, M.H.Cato, A.Anzelon-Mills, et al. (2006). Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling. Immunity 25:545–57.
-
(2006)
Immunity
, vol.25
, pp. 545-557
-
-
Omori, S.A.1
Cato, M.H.2
Anzelon-Mills, A.3
-
108
-
-
0035846955
-
Cd19-dependent activation of Akt kinase in B-lymphocytes
-
D.C.Otero, S.A.Omori, R.C.Rickert (2001). Cd19-dependent activation of Akt kinase in B-lymphocytes. J Biol Chem 276:1474–8.
-
(2001)
J Biol Chem
, vol.276
, pp. 1474-1478
-
-
Otero, D.C.1
Omori, S.A.2
Rickert, R.C.3
-
109
-
-
50449086797
-
BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells
-
K.L.Otipoby, Y.Sasaki, M.Schmidt-Supprian, et al. (2008). BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells. Proc Natl Acad Sci USA 105:12435–8.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 12435-12438
-
-
Otipoby, K.L.1
Sasaki, Y.2
Schmidt-Supprian, M.3
-
110
-
-
78650722178
-
Anticancer drugs that target metabolism: is dichloroacetate the new paradigm?
-
I.Papandreou, T.Goliasova, N.C.Denko (2011). Anticancer drugs that target metabolism:is dichloroacetate the new paradigm? Int J Cancer 128:1001–8.
-
(2011)
Int J Cancer
, vol.128
, pp. 1001-1008
-
-
Papandreou, I.1
Goliasova, T.2
Denko, N.C.3
-
111
-
-
84861455990
-
Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development
-
H.Park, K.Staehling, M.Tsang, et al. (2012). Disruption of Fnip1 reveals a metabolic checkpoint controlling B lymphocyte development. Immunity 36:769–81.
-
(2012)
Immunity
, vol.36
, pp. 769-781
-
-
Park, H.1
Staehling, K.2
Tsang, M.3
-
112
-
-
33750524262
-
BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism
-
A.Patke, I.Mecklenbrauker, H.Erdjument-Bromage, et al. (2006). BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism. J Exp Med 203:2551–62.
-
(2006)
J Exp Med
, vol.203
, pp. 2551-2562
-
-
Patke, A.1
Mecklenbrauker, I.2
Erdjument-Bromage, H.3
-
113
-
-
84945566427
-
A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling
-
H.C.Patterson, C.Gerbeth, P.Thiru, et al. (2015). A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling. Proc Natl Acad Sci USA 112:E5679–88.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
, pp. E5679-E5688
-
-
Patterson, H.C.1
Gerbeth, C.2
Thiru, P.3
-
114
-
-
84874196138
-
The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions
-
S.D.Pauls, S.T.Lafarge, I.Landego, et al. (2012). The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells:activation mechanisms, regulation and impact on cellular functions. Front Immunol 3:224.
-
(2012)
Front Immunol
, vol.3
, pp. 224
-
-
Pauls, S.D.1
Lafarge, S.T.2
Landego, I.3
-
115
-
-
67650096912
-
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
-
E.L.Pearce, M.C.Walsh, P.J.Cejas, et al. (2009). Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 460:103–7.
-
(2009)
Nature
, vol.460
, pp. 103-107
-
-
Pearce, E.L.1
Walsh, M.C.2
Cejas, P.J.3
-
116
-
-
84874097064
-
Plasma cells require autophagy for sustainable immunoglobulin production
-
N.Pengo, M.Scolari, L.Oliva, et al. (2013). Plasma cells require autophagy for sustainable immunoglobulin production. Nat Immunol 14:298–305.
-
(2013)
Nat Immunol
, vol.14
, pp. 298-305
-
-
Pengo, N.1
Scolari, M.2
Oliva, L.3
-
117
-
-
84880672380
-
PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma
-
M.Pfeifer, M.Grau, D.Lenze, et al. (2013). PTEN loss defines a PI3K/AKT pathway-dependent germinal center subtype of diffuse large B-cell lymphoma. Proc Natl Acad Sci USA 110:12420–5.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 12420-12425
-
-
Pfeifer, M.1
Grau, M.2
Lenze, D.3
-
118
-
-
0037452972
-
Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt
-
S.Qin, P.B.Chock (2003). Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt. Biochemistry 42:2995–3003.
-
(2003)
Biochemistry
, vol.42
, pp. 2995-3003
-
-
Qin, S.1
Chock, P.B.2
-
119
-
-
77956636063
-
The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development
-
F.Ramadani, D.J.Bolland, F.Garcon, et al. (2010). The PI3K isoforms p110alpha and p110delta are essential for pre-B cell receptor signaling and B cell development. Sci Signal 3:ra60.
-
(2010)
Sci Signal
, vol.3
, pp. ra60
-
-
Ramadani, F.1
Bolland, D.J.2
Garcon, F.3
-
120
-
-
0141863388
-
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival
-
J.C.Rathmell, C.J.Fox, D.R.Plas, et al. (2003). Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol Cell Biol 23:7315–28.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7315-7328
-
-
Rathmell, J.C.1
Fox, C.J.2
Plas, D.R.3
-
121
-
-
84944681622
-
The interleukin-2-mTORc1 kinase axis defines the signaling, differentiation, and metabolism of T Helper 1 and follicular B helper T cells
-
J.P.Ray, M.M.Staron, J.A.Shyer, et al. (2015). The interleukin-2-mTORc1 kinase axis defines the signaling, differentiation, and metabolism of T Helper 1 and follicular B helper T cells. Immunity 43:690–702.
-
(2015)
Immunity
, vol.43
, pp. 690-702
-
-
Ray, J.P.1
Staron, M.M.2
Shyer, J.A.3
-
122
-
-
4043082729
-
Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing
-
K.Reif, K.Okkenhaug, T.Sasaki, et al. (2004). Cutting edge:differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing. J Immunol 173:2236–40.
-
(2004)
J Immunol
, vol.173
, pp. 2236-2240
-
-
Reif, K.1
Okkenhaug, K.2
Sasaki, T.3
-
123
-
-
0036911138
-
Hydrogen peroxide as second messenger in lymphocyte activation
-
M.Reth (2002). Hydrogen peroxide as second messenger in lymphocyte activation. Nat Immunol 3:1129–34.
-
(2002)
Nat Immunol
, vol.3
, pp. 1129-1134
-
-
Reth, M.1
-
124
-
-
73249139454
-
BCR-induced superoxide negatively regulates B-cell proliferation and T-cell-independent type 2 Ab responses
-
S.M.Richards, E.A.Clark (2009). BCR-induced superoxide negatively regulates B-cell proliferation and T-cell-independent type 2 Ab responses. Eur J Immunol 39:3395–403.
-
(2009)
Eur J Immunol
, vol.39
, pp. 3395-3403
-
-
Richards, S.M.1
Clark, E.A.2
-
125
-
-
84880880724
-
New insights into pre-BCR and BCR signalling with relevance to B cell malignancies
-
R.C.Rickert (2013). New insights into pre-BCR and BCR signalling with relevance to B cell malignancies. Nat Rev Immunol 13:578–91.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 578-591
-
-
Rickert, R.C.1
-
126
-
-
0029064680
-
Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice
-
R.C.Rickert, K.Rajewsky, J.Roes (1995). Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice. Nature 376:352–5.
-
(1995)
Nature
, vol.376
, pp. 352-355
-
-
Rickert, R.C.1
Rajewsky, K.2
Roes, J.3
-
127
-
-
84882321254
-
Akt phosphorylates HK-II at Thr-473 and increases mitochondrial HK-II association to protect cardiomyocytes
-
D.J.Roberts, V.P.Tan-Sah, J.M.Smith, S.Miyamoto (2013). Akt phosphorylates HK-II at Thr-473 and increases mitochondrial HK-II association to protect cardiomyocytes. J Biol Chem 288:23798–806.
-
(2013)
J Biol Chem
, vol.288
, pp. 23798-23806
-
-
Roberts, D.J.1
Tan-Sah, V.P.2
Smith, J.M.3
Miyamoto, S.4
-
128
-
-
84963625936
-
PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones
-
S.Sander, V.T.Chu, T.Yasuda, et al. (2015). PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones. Immunity 43:1075–86.
-
(2015)
Immunity
, vol.43
, pp. 1075-1086
-
-
Sander, S.1
Chu, V.T.2
Yasuda, T.3
-
129
-
-
17444377916
-
The strength of receptor signaling is centrally controlled through a cooperative loop between Ca2+ and an oxidant signal
-
D.K.Singh, D.Kumar, Z.Siddiqui, et al. (2005). The strength of receptor signaling is centrally controlled through a cooperative loop between Ca2+ and an oxidant signal. Cell 121:281–93.
-
(2005)
Cell
, vol.121
, pp. 281-293
-
-
Singh, D.K.1
Kumar, D.2
Siddiqui, Z.3
-
130
-
-
82655176963
-
IKKbeta and NF-kappaB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1
-
T.G.Sommermann, K.O'Neill, D.R.Plas, E.Cahir-McFarland (2011). IKKbeta and NF-kappaB transcription govern lymphoma cell survival through AKT-induced plasma membrane trafficking of GLUT1. Cancer Res 71:7291–300.
-
(2011)
Cancer Res
, vol.71
, pp. 7291-7300
-
-
Sommermann, T.G.1
O'Neill, K.2
Plas, D.R.3
Cahir-McFarland, E.4
-
131
-
-
70350304558
-
PI3 kinase signals BCR-dependent mature B cell survival
-
L.Srinivasan, Y.Sasaki, D.P.Calado, et al. (2009). PI3 kinase signals BCR-dependent mature B cell survival. Cell 139:573–86.
-
(2009)
Cell
, vol.139
, pp. 573-586
-
-
Srinivasan, L.1
Sasaki, Y.2
Calado, D.P.3
-
132
-
-
84885055994
-
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
-
M.Sukumar, J.Liu, Y.Ji, et al. (2013). Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function. J Clin Invest 123:4479–88.
-
(2013)
J Clin Invest
, vol.123
, pp. 4479-4488
-
-
Sukumar, M.1
Liu, J.2
Ji, Y.3
-
133
-
-
33947316888
-
Glycogen synthase kinase-3 phosphorylates and regulates the stability of p27kip1 protein
-
M.Surjit, S.K.Lal (2007). Glycogen synthase kinase-3 phosphorylates and regulates the stability of p27kip1 protein. Cell Cycle 6:580–8.
-
(2007)
Cell Cycle
, vol.6
, pp. 580-588
-
-
Surjit, M.1
Lal, S.K.2
-
134
-
-
0027515127
-
Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling
-
C.Sutherland, I.A.Leighton, P.Cohen (1993). Inactivation of glycogen synthase kinase-3 beta by phosphorylation:new kinase connections in insulin and growth-factor signalling. Biochem J 296:15–9.
-
(1993)
Biochem J
, vol.296
, pp. 15-19
-
-
Sutherland, C.1
Leighton, I.A.2
Cohen, P.3
-
135
-
-
0037416216
-
Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination
-
A.Suzuki, T.Kaisho, M.Ohishi, et al. (2003a). Critical roles of Pten in B cell homeostasis and immunoglobulin class switch recombination. J Exp Med 197:657–67.
-
(2003)
J Exp Med
, vol.197
, pp. 657-667
-
-
Suzuki, A.1
Kaisho, T.2
Ohishi, M.3
-
136
-
-
0037414761
-
Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein
-
A.Suzuki, G.Kusakai, A.Kishimoto, et al. (2003b). Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein. J Biol Chem 278:48–53.
-
(2003)
J Biol Chem
, vol.278
, pp. 48-53
-
-
Suzuki, A.1
Kusakai, G.2
Kishimoto, A.3
-
137
-
-
84951852496
-
Glycogen synthase kinase 3 in Wnt signaling pathway and cancer
-
N.Tejeda-Munoz, M.Robles-Flores (2015). Glycogen synthase kinase 3 in Wnt signaling pathway and cancer. IUBMB Life 67:914–22.
-
(2015)
IUBMB Life
, vol.67
, pp. 914-922
-
-
Tejeda-Munoz, N.1
Robles-Flores, M.2
-
138
-
-
84866976187
-
Inhibition of fatty acid metabolism reduces human myeloma cells proliferation
-
J.M.Tirado-Velez, I.Joumady, A.Saez-Benito, et al. (2012). Inhibition of fatty acid metabolism reduces human myeloma cells proliferation. PLoS One 7:e46484.
-
(2012)
PLoS One
, vol.7
, pp. e46484
-
-
Tirado-Velez, J.M.1
Joumady, I.2
Saez-Benito, A.3
-
139
-
-
20444400257
-
Redox redux: revisiting PTPs and the control of cell signaling
-
N.K.Tonks (2005). Redox redux:revisiting PTPs and the control of cell signaling. Cell 121:667–70.
-
(2005)
Cell
, vol.121
, pp. 667-670
-
-
Tonks, N.K.1
-
140
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Z.Tothova, R.Kollipara, B.J.Huntly, et al. (2007). FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128:325–39.
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
-
141
-
-
0027169534
-
CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase
-
D.A.Tuveson, R.H.Carter, S.P.Soltoff, D.T.Fearon (1993). CD19 of B cells as a surrogate kinase insert region to bind phosphatidylinositol 3-kinase. Science 260:986–9.
-
(1993)
Science
, vol.260
, pp. 986-989
-
-
Tuveson, D.A.1
Carter, R.H.2
Soltoff, S.P.3
Fearon, D.T.4
-
142
-
-
84856183120
-
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
-
G.J.Van Der Windt, B.Everts, C.H.Chang, et al. (2012). Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. Immunity 36:68–78.
-
(2012)
Immunity
, vol.36
, pp. 68-78
-
-
Van Der Windt, G.J.1
Everts, B.2
Chang, C.H.3
-
143
-
-
84890701538
-
Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells
-
J.Velez, N.HailJr., M.Konopleva, et al. (2013). Mitochondrial uncoupling and the reprograming of intermediary metabolism in leukemia cells. Front Oncol 3:67.
-
(2013)
Front Oncol
, vol.3
, pp. 67
-
-
Velez, J.1
Hail, N.2
Konopleva, M.3
-
144
-
-
77956300467
-
Redox remodeling allows and controls B-cell activation and differentiation
-
R.Vene, L.Delfino, P.Castellani, et al. (2010). Redox remodeling allows and controls B-cell activation and differentiation. Antioxid Redox Signal 13:1145–55.
-
(2010)
Antioxid Redox Signal
, vol.13
, pp. 1145-1155
-
-
Vene, R.1
Delfino, L.2
Castellani, P.3
-
145
-
-
84875960670
-
PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development
-
R.K.Venigalla, V.A.McGuire, R.Clarke, et al. (2013). PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development. Embo J 32:1008–22.
-
(2013)
Embo J
, vol.32
, pp. 1008-1022
-
-
Venigalla, R.K.1
McGuire, V.A.2
Clarke, R.3
-
146
-
-
78149477766
-
Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter
-
G.D.Victora, T.A.Schwickert, D.R.Fooksman, et al. (2010). Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter. Cell 143:592–605.
-
(2010)
Cell
, vol.143
, pp. 592-605
-
-
Victora, G.D.1
Schwickert, T.A.2
Fooksman, D.R.3
-
148
-
-
84869147050
-
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
-
R.C.Wang, Y.Wei, Z.An, et al. (2012). Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation. Science 338:956–9.
-
(2012)
Science
, vol.338
, pp. 956-959
-
-
Wang, R.C.1
Wei, Y.2
An, Z.3
-
149
-
-
79956292375
-
Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2
-
M.Watanabe-Matsui, A.Muto, T.Matsui, et al. (2011). Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2. Blood 117:5438–48.
-
(2011)
Blood
, vol.117
, pp. 5438-5448
-
-
Watanabe-Matsui, M.1
Muto, A.2
Matsui, T.3
-
150
-
-
77955876805
-
Role of PI3K in the generation and survival of B cells
-
M.Werner, E.Hobeika, H.Jumaa (2010). Role of PI3K in the generation and survival of B cells. Immunol Rev 237:55–71.
-
(2010)
Immunol Rev
, vol.237
, pp. 55-71
-
-
Werner, M.1
Hobeika, E.2
Jumaa, H.3
-
151
-
-
84867916343
-
Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation
-
M.L.Wheeler, A.L.Defranco (2012). Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation. J Immunol 189:4405–16.
-
(2012)
J Immunol
, vol.189
, pp. 4405-4416
-
-
Wheeler, M.L.1
Defranco, A.L.2
-
152
-
-
0025132636
-
Suppression of B cell activation by cyclosporin A, FK506 and rapamycin
-
L.S.Wicker, R.C.BoltzJr, V.Matt, et al. (1990). Suppression of B cell activation by cyclosporin A, FK506 and rapamycin. Eur J Immunol 20:2277–83.
-
(1990)
Eur J Immunol
, vol.20
, pp. 2277-2283
-
-
Wicker, L.S.1
Boltz, R.C.2
Matt, V.3
-
153
-
-
38349158386
-
Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival
-
R.T.Woodland, C.J.Fox, M.R.Schmidt, et al. (2008). Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival. Blood 111:750–60.
-
(2008)
Blood
, vol.111
, pp. 750-760
-
-
Woodland, R.T.1
Fox, C.J.2
Schmidt, M.R.3
-
154
-
-
84873469666
-
Nutrient sensing, metabolism, and cell growth control
-
H.X.Yuan, Y.Xiong, K.L.Guan (2013). Nutrient sensing, metabolism, and cell growth control. Mol Cell 49:379–87.
-
(2013)
Mol Cell
, vol.49
, pp. 379-387
-
-
Yuan, H.X.1
Xiong, Y.2
Guan, K.L.3
-
155
-
-
1542608799
-
Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray
-
H.Zha, M.Raffeld, L.Charboneau, et al. (2004). Similarities of prosurvival signals in Bcl-2-positive and Bcl-2-negative follicular lymphomas identified by reverse phase protein microarray. Lab Invest 84:235–44.
-
(2004)
Lab Invest
, vol.84
, pp. 235-244
-
-
Zha, H.1
Raffeld, M.2
Charboneau, L.3
-
156
-
-
84905384484
-
Rictor is required for early B cell development in bone marrow
-
Y.Zhang, T.Hu, C.Hua, et al. (2014). Rictor is required for early B cell development in bone marrow. PLoS One 9:e103970.
-
(2014)
PLoS One
, vol.9
, pp. e103970
-
-
Zhang, Y.1
Hu, T.2
Hua, C.3
-
157
-
-
84881399035
-
B cell-specific deficiencies in mTOR limit humoral immune responses
-
S.Zhang, M.Pruitt, D.Tran, et al. (2013). B cell-specific deficiencies in mTOR limit humoral immune responses. J Immunol 191:1692–703.
-
(2013)
J Immunol
, vol.191
, pp. 1692-1703
-
-
Zhang, S.1
Pruitt, M.2
Tran, D.3
-
158
-
-
79251569252
-
Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production
-
S.Zhang, J.A.Readinger, W.Dubois, et al. (2011). Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production. Blood 117:1228–38.
-
(2011)
Blood
, vol.117
, pp. 1228-1238
-
-
Zhang, S.1
Readinger, J.A.2
Dubois, W.3
-
159
-
-
34250179471
-
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1
-
Y.Zhao, B.J.Altman, J.L.Coloff, et al. (2007). Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Mol Cell Biol 27:4328–39.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 4328-4339
-
-
Zhao, Y.1
Altman, B.J.2
Coloff, J.L.3
|