-
1
-
-
45149117024
-
Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: Mapping the site of binding
-
Abu-Hamad, S., Zaid, H., Israelson, A., Nahon, E., and Shoshan-Barmatz, V. (2008). Hexokinase-I protection against apoptotic cell death is mediated via interaction with the voltage-dependent anion channel-1: Mapping the site of binding. J. Biol. Chem. 283, 13482-13490.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13482-13490
-
-
Abu-Hamad, S.1
Zaid, H.2
Israelson, A.3
Nahon, E.4
Shoshan-Barmatz, V.5
-
2
-
-
0028035447
-
Regulation of cell proliferation under extreme and moderate hypoxia: The role of pyrimidine (deoxy)nucleotides
-
Amellem, O., Löffler, M., and Pettersen, E. O. (1994). Regulation of cell proliferation under extreme and moderate hypoxia: The role of pyrimidine (deoxy)nucleotides. Br. J. Cancer 70, 857-866.
-
(1994)
Br. J. Cancer
, vol.70
, pp. 857-866
-
-
Amellem, O.1
Löffler, M.2
Pettersen, E.O.3
-
3
-
-
0023704192
-
Subcellular distribution of hexokinase in leukemic and stimulated lymphoid cells of mice
-
Arany, I., Ember, I., and Rady, P. (1988). Subcellular distribution of hexokinase in leukemic and stimulated lymphoid cells of mice. Haematologia (Budap.) 21, 109-114.
-
(1988)
Haematologia (Budap.)
, vol.21
, pp. 109-114
-
-
Arany, I.1
Ember, I.2
Rady, P.3
-
4
-
-
0035862197
-
Bcl-2 inhibits apoptosis induced by mitochondrial uncoupling but does not prevent mitochondrial transmembrane depolarization
-
Armstrong, J. S., Steinauer, K. K., French, J., Killoran, P. L., Walleczek, J., Kochanski, J., et al. (2001). Bcl-2 inhibits apoptosis induced by mitochondrial uncoupling but does not prevent mitochondrial transmembrane depolarization. Exp. Cell Res. 262, 170-179.
-
(2001)
Exp. Cell Res.
, vol.262
, pp. 170-179
-
-
Armstrong, J.S.1
Steinauer, K.K.2
French, J.3
Killoran, P.L.4
Walleczek, J.5
Kochanski, J.6
-
5
-
-
80051628334
-
Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR-104
-
doi:10.1371/journal.pone.0023108
-
Benito, J., Shi, Y., Szymanska, B., Carol, H., Boehm, I., Lu, H., et al. (2011). Pronounced hypoxia in models of murine and human leukemia: High efficacy of hypoxia-activated prodrug PR-104. PLoS ONE 6:e23108. doi:10.1371/journal.pone.0023108
-
(2011)
PLoS ONE
, vol.6
-
-
Benito, J.1
Shi, Y.2
Szymanska, B.3
Carol, H.4
Boehm, I.5
Lu, H.6
-
7
-
-
0034656164
-
Indirect inhibition of mitochondrial dihydroorotate dehydrogenase activity by nitric oxide
-
Beuneu, C., Auger, R., Loffler, M., Guissani, A., Lemaire, G., and Lepoivre, M. (2000). Indirect inhibition of mitochondrial dihydroorotate dehydrogenase activity by nitric oxide. Free Radic. Biol. Med. 28, 1206-1213.
-
(2000)
Free Radic. Biol. Med.
, vol.28
, pp. 1206-1213
-
-
Beuneu, C.1
Auger, R.2
Loffler, M.3
Guissani, A.4
Lemaire, G.5
Lepoivre, M.6
-
8
-
-
0346535447
-
Fatty acid oxidation and ketogenesis in transplantable liver tumors
-
Bloch-Frankenthal, L., Langan, J., Morris, H. P., and Weinhouse, S. (1965). Fatty acid oxidation and ketogenesis in transplantable liver tumors. Cancer Res. 25, 732-736.
-
(1965)
Cancer Res.
, vol.25
, pp. 732-736
-
-
Bloch-Frankenthal, L.1
Langan, J.2
Morris, H.P.3
Weinhouse, S.4
-
9
-
-
33846002728
-
A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
Bonnet, S., Archer, S. L., Allalunis-Turner, J., Haromy, A., Beaulieu, C., Thompson, R., et al. (2007). A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 11, 37-51.
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
Haromy, A.4
Beaulieu, C.5
Thompson, R.6
-
10
-
-
65449119234
-
Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate
-
Chen, Z., Zhang, H., Lu, W., and Huang, P. (2009). Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. Biochim. Biophys. Acta 1787, 553-560.
-
(2009)
Biochim. Biophys. Acta
, vol.1787
, pp. 553-560
-
-
Chen, Z.1
Zhang, H.2
Lu, W.3
Huang, P.4
-
11
-
-
46649106720
-
Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels
-
doi:10.1371/journal.pone.0001852
-
Chiara, F., Castellaro, D., Marin, O., Petronilli, V., Brusilow, W. S., Juhaszova, M., et al. (2008). Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels. PLoS ONE 3:e1852. doi:10.1371/journal.pone.0001852
-
(2008)
PLoS ONE
, vol.3
-
-
Chiara, F.1
Castellaro, D.2
Marin, O.3
Petronilli, V.4
Brusilow, W.S.5
Juhaszova, M.6
-
12
-
-
0032803798
-
Palmitate induces apoptosis via a direct effect on mitochondria
-
de Pablo, M. A., Susin, S. A., Jacotot, E., Larochette, N., Costantini, P., Ravagnan, L., et al. (1999). Palmitate induces apoptosis via a direct effect on mitochondria. Apoptosis 4, 81-87.
-
(1999)
Apoptosis
, vol.4
, pp. 81-87
-
-
de Pablo, M.A.1
Susin, S.A.2
Jacotot, E.3
Larochette, N.4
Costantini, P.5
Ravagnan, L.6
-
13
-
-
80052775587
-
Serine metabolism: Some tumors take the road less traveled
-
DeBerardinis, R. J. (2011). Serine metabolism: Some tumors take the road less traveled. Cell Metab. 14, 285-286.
-
(2011)
Cell Metab.
, vol.14
, pp. 285-286
-
-
DeBerardinis, R.J.1
-
14
-
-
37449034854
-
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
-
DeBerardinis, R. J., Mancuso, A., Daikhin, E., Nissim, I., Yudkoff, M., Wehrli, S., et al. (2007). Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc. Natl. Acad. Sci. U.S.A. 104, 19345-19350.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 19345-19350
-
-
DeBerardinis, R.J.1
Mancuso, A.2
Daikhin, E.3
Nissim, I.4
Yudkoff, M.5
Wehrli, S.6
-
15
-
-
42349088894
-
The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells
-
Derdak, Z., Mark, N. M., Beldi, G., Robson, S. C., Wands, J. R., and Baffy, G. (2008). The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells. Cancer Res. 68, 2813-2819.
-
(2008)
Cancer Res.
, vol.68
, pp. 2813-2819
-
-
Derdak, Z.1
Mark, N.M.2
Beldi, G.3
Robson, S.C.4
Wands, J.R.5
Baffy, G.6
-
16
-
-
4043064372
-
Mammalian pyrimidine biosynthesis: Fresh insights into an ancient pathway
-
Evans, D. R., and Guy, H. I. (2004). Mammalian pyrimidine biosynthesis: Fresh insights into an ancient pathway. J. Biol. Chem. 279, 33035-33038.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33035-33038
-
-
Evans, D.R.1
Guy, H.I.2
-
17
-
-
61849173436
-
CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure
-
Fiegl, M., Samudio, I., Clise-Dwyer, K., Burks, J. K., Mnjoyan, Z., and Andreeff, M. (2009). CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure. Blood 113, 1504-1512.
-
(2009)
Blood
, vol.113
, pp. 1504-1512
-
-
Fiegl, M.1
Samudio, I.2
Clise-Dwyer, K.3
Burks, J.K.4
Mnjoyan, Z.5
Andreeff, M.6
-
18
-
-
84868347607
-
Metabolic plasticity in stem cell homeostasis and differentiation
-
Folmes, C. D., Dzeja, P. P., Nelson, T. J., and Terzic, A. (2012). Metabolic plasticity in stem cell homeostasis and differentiation. Cell Stem Cell 11, 596-606.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 596-606
-
-
Folmes, C.D.1
Dzeja, P.P.2
Nelson, T.J.3
Terzic, A.4
-
19
-
-
0016750459
-
Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid
-
Forman, J. H., and Kennedy, J. (1975). Superoxide production and electron transport in mitochondrial oxidation of dihydroorotic acid. J. Biol. Chem. 250, 4322-4326.
-
(1975)
J. Biol. Chem.
, vol.250
, pp. 4322-4326
-
-
Forman, J.H.1
Kennedy, J.2
-
21
-
-
0033711215
-
Improved energy homeostasis of the heart in the metabolic state of exercise
-
Goodwin, G. W., and Taegtmeyer, H. (2000). Improved energy homeostasis of the heart in the metabolic state of exercise. Am. J. Physiol. Heart Circ. Physiol. 279, H1490-1501.
-
(2000)
Am. J. Physiol. Heart Circ. Physiol.
, vol.279
-
-
Goodwin, G.W.1
Taegtmeyer, H.2
-
22
-
-
78650065328
-
Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous keratinocytes
-
Hail, N. Jr., Chen, P., Rower, J., and Bushman, L. R. (2010a). Teriflunomide encourages cytostatic and apoptotic effects in premalignant and malignant cutaneous keratinocytes. Apoptosis 15, 1234-1246.
-
(2010)
Apoptosis
, vol.15
, pp. 1234-1246
-
-
Hail Jr., N.1
Chen, P.2
Rower, J.3
Bushman, L.R.4
-
23
-
-
78650178712
-
The hydroxyl functional group of N-(4-hydroxyphenyl)retinamide mediates cellular uptake and cytotoxicity in premalignant and malignant human epithelial cells
-
Hail, N. Jr., Chen, P., and Wempe, M. F. (2010b). The hydroxyl functional group of N-(4-hydroxyphenyl)retinamide mediates cellular uptake and cytotoxicity in premalignant and malignant human epithelial cells. Free Radic. Biol. Med. 49, 2001-2009.
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 2001-2009
-
-
Hail Jr., N.1
Chen, P.2
Wempe, M.F.3
-
24
-
-
58149340242
-
Cancer chemoprevention and mitochondria: Targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state
-
Hail, N. Jr., and Lotan, R. (2009). Cancer chemoprevention and mitochondria: Targeting apoptosis in transformed cells via the disruption of mitochondrial bioenergetics/redox state. Mol. Nutr. Food Res. 53, 49-67.
-
(2009)
Mol. Nutr. Food Res.
, vol.53
, pp. 49-67
-
-
Hail Jr., N.1
Lotan, R.2
-
25
-
-
0036738149
-
Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins
-
Konopleva, M., Konoplev, S., Hu, W., Zaritskey, A. Y., Afanasiev, B. V., and Andreeff, M. (2002). Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins. Leukemia 16, 1713-1724.
-
(2002)
Leukemia
, vol.16
, pp. 1713-1724
-
-
Konopleva, M.1
Konoplev, S.2
Hu, W.3
Zaritskey, A.Y.4
Afanasiev, B.V.5
Andreeff, M.6
-
26
-
-
0009636918
-
Acetopyruvic acid (alphagamma-diketovaleric acid) as an intermediate metabolite in animal tissues
-
Krebs, H. A., and Johnson, W. A. (1937). Acetopyruvic acid (alphagamma-diketovaleric acid) as an intermediate metabolite in animal tissues. Biochem. J. 31, 772-779.
-
(1937)
Biochem. J.
, vol.31
, pp. 772-779
-
-
Krebs, H.A.1
Johnson, W.A.2
-
27
-
-
35948984131
-
The formation of citric and alpha-ketoglutaric acids in the mammalian body
-
Krebs, H. A., Salvin, E., and Johnson, W. A. (1938). The formation of citric and alpha-ketoglutaric acids in the mammalian body. Biochem. J. 32, 113-117.
-
(1938)
Biochem. J.
, vol.32
, pp. 113-117
-
-
Krebs, H.A.1
Salvin, E.2
Johnson, W.A.3
-
28
-
-
67349227911
-
Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway
-
Kui, L., Weiwei, Z., Ling, L., Daikun, H., Guoming, Z., Linuo, Z., et al. (2009). Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway. Regul. Pept. 155, 62-69.
-
(2009)
Regul. Pept.
, vol.155
, pp. 62-69
-
-
Kui, L.1
Weiwei, Z.2
Ling, L.3
Daikun, H.4
Guoming, Z.5
Linuo, Z.6
-
29
-
-
84875143073
-
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells
-
Lagadinou, E. D., Sach, A., Callahan, K., Rossi, R. M., Neering, S. J., Minhajuddin, M., et al. (2013). BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells. Cell Stem Cell 12, 329-341.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 329-341
-
-
Lagadinou, E.D.1
Sach, A.2
Callahan, K.3
Rossi, R.M.4
Neering, S.J.5
Minhajuddin, M.6
-
30
-
-
0026334497
-
Evidence from in vitro studies that dihydroorotate dehydrogenase may be a source of toxic oxygen species
-
Lakaschus, G., Krüger, H., Heese, D., and Löffler, M. (1991). Evidence from in vitro studies that dihydroorotate dehydrogenase may be a source of toxic oxygen species. Adv. Exp. Med. Biol. 309A, 361-364.
-
(1991)
Adv. Exp. Med. Biol.
, vol.309 A
, pp. 361-364
-
-
Lakaschus, G.1
Krüger, H.2
Heese, D.3
Löffler, M.4
-
31
-
-
84855453655
-
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells
-
Le, A., Lane, A. N., Hamaker, M., Bose, S., Gouw, A., Barbi, J., et al. (2012). Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metab. 15, 110-121.
-
(2012)
Cell Metab.
, vol.15
, pp. 110-121
-
-
Le, A.1
Lane, A.N.2
Hamaker, M.3
Bose, S.4
Gouw, A.5
Barbi, J.6
-
32
-
-
0036139856
-
The mitochondrial production of reactive oxygen species: Mechanisms and implications in human pathology
-
Lenaz, G. (2001). The mitochondrial production of reactive oxygen species: Mechanisms and implications in human pathology. IUBMB Life 52, 159-164.
-
(2001)
IUBMB Life
, vol.52
, pp. 159-164
-
-
Lenaz, G.1
-
33
-
-
0024341665
-
The biosynthetic pathway of pyrimidine (deoxy)nucleotides: A sensor of oxygen tension necessary for maintaining cell proliferation?
-
Löffler, M. (1989). The biosynthetic pathway of pyrimidine (deoxy)nucleotides: A sensor of oxygen tension necessary for maintaining cell proliferation? Exp. Cell Res. 182, 637-680.
-
(1989)
Exp. Cell Res.
, vol.182
, pp. 637-680
-
-
Löffler, M.1
-
34
-
-
77954922243
-
Bcl-2 modulates resveratrol-induced ROS production by regulating mitochondrial respiration in tumor cells
-
Low, I. C., Chen, Z. X., and Pervaiz, S. (2010). Bcl-2 modulates resveratrol-induced ROS production by regulating mitochondrial respiration in tumor cells. Antioxid. Redox Signal. 13, 807-819.
-
(2010)
Antioxid. Redox Signal.
, vol.13
, pp. 807-819
-
-
Low, I.C.1
Chen, Z.X.2
Pervaiz, S.3
-
35
-
-
0033991590
-
Cytoarchitecture and physical properties of cytoplasm: Volume, viscosity, diffusion, intracellular surface area
-
Luby-Phelps, K. (2000). Cytoarchitecture and physical properties of cytoplasm: Volume, viscosity, diffusion, intracellular surface area. Int. Rev. Cytol. 192, 189-221.
-
(2000)
Int. Rev. Cytol.
, vol.192
, pp. 189-221
-
-
Luby-Phelps, K.1
-
36
-
-
34250953915
-
Die Rolle der Phosphorsaeure bei Dehydrierungsvorgaengen und ihre biologische Bedeutung
-
Lynen, F. (1951). Die Rolle der Phosphorsaeure bei Dehydrierungsvorgaengen und ihre biologische Bedeutung. Naturwissenschaften 30, 398-406.
-
(1951)
Naturwissenschaften
, vol.30
, pp. 398-406
-
-
Lynen, F.1
-
37
-
-
9744221185
-
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
-
Majewski, N., Nogueira, V., Bhaskar, P., Coy, P. E., Skeen, J. E., Gottlob, K., et al. (2004a). Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Mol. Cell 16, 819-830.
-
(2004)
Mol. Cell
, vol.16
, pp. 819-830
-
-
Majewski, N.1
Nogueira, V.2
Bhaskar, P.3
Coy, P.E.4
Skeen, J.E.5
Gottlob, K.6
-
38
-
-
0347986675
-
Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases
-
Majewski, N., Nogueira, V., Robey, R. B., and Hay, N. (2004b). Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases. Mol. Cell. Biol. 24, 730-740.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 730-740
-
-
Majewski, N.1
Nogueira, V.2
Robey, R.B.3
Hay, N.4
-
39
-
-
77953812468
-
The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies
-
Mathupala, S. P., Ko, Y. H., and Pedersen, P. L. (2010). The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies. Biochim. Biophys. Acta 1797, 1225-1230.
-
(2010)
Biochim. Biophys. Acta
, vol.1797
, pp. 1225-1230
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
40
-
-
84856014884
-
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
-
Metallo, C. M., Gameiro, P. A., Bell, E. L., Mattaini, K. R., Yang, J., Hiller, K., et al. (2012). Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature 481, 380-384.
-
(2012)
Nature
, vol.481
, pp. 380-384
-
-
Metallo, C.M.1
Gameiro, P.A.2
Bell, E.L.3
Mattaini, K.R.4
Yang, J.5
Hiller, K.6
-
41
-
-
40749102909
-
The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells
-
Ringshausen, I., Oelsner, M., Bogner, C., Peschel, C., and Decker, T. (2008). The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells. Leukemia 22, 635-638.
-
(2008)
Leukemia
, vol.22
, pp. 635-638
-
-
Ringshausen, I.1
Oelsner, M.2
Bogner, C.3
Peschel, C.4
Decker, T.5
-
42
-
-
53149115638
-
The effect of dinitrophenol on the metabolism of frog muscle
-
Ronzoni, E., and Ehrenfest, E. (1936). The effect of dinitrophenol on the metabolism of frog muscle. J. Biol. Chem. 15, 749.
-
(1936)
J. Biol. Chem.
, vol.15
, pp. 749
-
-
Ronzoni, E.1
Ehrenfest, E.2
-
43
-
-
0032555586
-
Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans
-
Rückemann, K., Fairbanks, L. D., Carrey, E. A., Hawrylowicz, C. M., Richards, D. F., Kirschbaum, B., et al. (1998). Leflunomide inhibits pyrimidine de novo synthesis in mitogen-stimulated T-lymphocytes from healthy humans. J. Biol. Chem. 273, 21682-21691.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 21682-21691
-
-
Rückemann, K.1
Fairbanks, L.D.2
Carrey, E.A.3
Hawrylowicz, C.M.4
Richards, D.F.5
Kirschbaum, B.6
-
44
-
-
65549123260
-
Mitochondrial uncoupling and the Warburg effect: Molecular basis for the reprogramming of cancer cell metabolism
-
Samudio, I., Fiegl, M., and Andreeff, M. (2009). Mitochondrial uncoupling and the Warburg effect: Molecular basis for the reprogramming of cancer cell metabolism. Cancer Res. 69, 2163-2166.
-
(2009)
Cancer Res.
, vol.69
, pp. 2163-2166
-
-
Samudio, I.1
Fiegl, M.2
Andreeff, M.3
-
45
-
-
48549088300
-
The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation
-
Samudio, I., Fiegl, M., McQueen, T., Clise-Dwyer, K., and Andreeff, M. (2008). The Warburg effect in leukemia-stroma cocultures is mediated by mitochondrial uncoupling associated with uncoupling protein 2 activation. Cancer Res. 68, 5198-5205.
-
(2008)
Cancer Res.
, vol.68
, pp. 5198-5205
-
-
Samudio, I.1
Fiegl, M.2
McQueen, T.3
Clise-Dwyer, K.4
Andreeff, M.5
-
46
-
-
74949089659
-
Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
-
Samudio, I., Harmancey, R., Fiegl, M., Kantarjian, H., Konopleva, M., Korchin, B., et al. (2010). Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. J. Clin. Invest. 120, 142-156.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 142-156
-
-
Samudio, I.1
Harmancey, R.2
Fiegl, M.3
Kantarjian, H.4
Konopleva, M.5
Korchin, B.6
-
47
-
-
38449123007
-
Leflunomide inhibits PDK1/Akt pathway and induces apoptosis of human mast cells
-
Sawamukai, N., Saito, K., Yamaoka, K., Nakayamada, S., Ra, C., and Tanaka, Y. (2007). Leflunomide inhibits PDK1/Akt pathway and induces apoptosis of human mast cells. J. Immunol. 179, 6479-6484.
-
(2007)
J. Immunol.
, vol.179
, pp. 6479-6484
-
-
Sawamukai, N.1
Saito, K.2
Yamaoka, K.3
Nakayamada, S.4
Ra, C.5
Tanaka, Y.6
-
48
-
-
82755183511
-
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect
-
Scott, D. A., Richardson, A. D., Filipp, F. V., Knutzen, C. A., Chiang, G. G., Ronai, Z. A., et al. (2011). Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. J. Biol. Chem. 286, 42626-42634.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 42626-42634
-
-
Scott, D.A.1
Richardson, A.D.2
Filipp, F.V.3
Knutzen, C.A.4
Chiang, G.G.5
Ronai, Z.A.6
-
49
-
-
0030811256
-
Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide
-
Shawver, L. K., Schwartz, D. P., Mann, E., Chen, H., Tsai, J., Chu, L., et al. (1997). Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide. Clin. Cancer Res. 3, 1167-1177.
-
(1997)
Clin. Cancer Res.
, vol.3
, pp. 1167-1177
-
-
Shawver, L.K.1
Schwartz, D.P.2
Mann, E.3
Chen, H.4
Tsai, J.5
Chu, L.6
-
50
-
-
42049090589
-
Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice
-
Sheets, A. R., Fulop, P., Derdak, Z., Kassai, A., Sabo, E., Mark, N. M., et al. (2008). Uncoupling protein-2 modulates the lipid metabolic response to fasting in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 294, G1017-G1024.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.294
-
-
Sheets, A.R.1
Fulop, P.2
Derdak, Z.3
Kassai, A.4
Sabo, E.5
Mark, N.M.6
-
51
-
-
84856510610
-
VDAC, a multi-functional mitochondrial protein as a pharmacological target
-
Shoshan-Barmatz, V., and Ben-Hail, D. (2012). VDAC, a multi-functional mitochondrial protein as a pharmacological target. Mitochondrion 12, 24-34.
-
(2012)
Mitochondrion
, vol.12
, pp. 24-34
-
-
Shoshan-Barmatz, V.1
Ben-Hail, D.2
-
52
-
-
77952886494
-
VDAC, a multi-functional mitochondrial protein regulating cell life and death
-
Shoshan-Barmatz, V., De Pinto, V., Zweckstetter, M., Raviv, Z., Keinan, N., and Arbel, N. (2010). VDAC, a multi-functional mitochondrial protein regulating cell life and death. Mol. Aspects Med. 31, 227-285.
-
(2010)
Mol. Aspects Med.
, vol.31
, pp. 227-285
-
-
Shoshan-Barmatz, V.1
De Pinto, V.2
Zweckstetter, M.3
Raviv, Z.4
Keinan, N.5
Arbel, N.6
-
53
-
-
79955777637
-
Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism
-
doi:10.1371/journal.pone.0019645
-
Smerc, A., Sodja, E., and Legisa, M. (2011). Posttranslational modification of 6-phosphofructo-1-kinase as an important feature of cancer metabolism. PLoS ONE 6:e19645. doi:10.1371/journal.pone.0019645
-
(2011)
PLoS ONE
, vol.6
-
-
Smerc, A.1
Sodja, E.2
Legisa, M.3
-
54
-
-
0028143584
-
Physiological concentrations of purines and pyrimidines
-
Traut, T. W. (1994). Physiological concentrations of purines and pyrimidines. Mol. Cell. Biochem. 140, 1-22.
-
(1994)
Mol. Cell. Biochem.
, vol.140
, pp. 1-22
-
-
Traut, T.W.1
-
55
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. (1956). On the origin of cancer cells. Science 123, 309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
56
-
-
0000459772
-
über den Stoffwechsel der Tumoren
-
Warburg, O., Posener, K., and Negelein, E. (1924). über den Stoffwechsel der Tumoren. Biochem. Z. 152, 319-344.
-
(1924)
Biochem. Z.
, vol.152
, pp. 319-344
-
-
Warburg, O.1
Posener, K.2
Negelein, E.3
-
57
-
-
0015409718
-
Glycolysis, respiration, and anomalous gene expression in experimental hepatomas: G.H.A
-
Weinhouse, S. (1972). Glycolysis, respiration, and anomalous gene expression in experimental hepatomas: G.H.A. Clowes memorial lecture. Cancer Res. 32, 2007-2016.
-
(1972)
Clowes memorial lecture. Cancer Res.
, vol.32
, pp. 2007-2016
-
-
Weinhouse, S.1
-
58
-
-
84855469557
-
Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione
-
Wilkins, H. M., Marquardt, K., Lash, L. H., and Linseman, D. A. (2012). Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione. Free Radic. Biol. Med. 52, 410-419.
-
(2012)
Free Radic. Biol. Med.
, vol.52
, pp. 410-419
-
-
Wilkins, H.M.1
Marquardt, K.2
Lash, L.H.3
Linseman, D.A.4
-
59
-
-
83755178091
-
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of alpha-ketoglutarate to citrate to support cell growth and viability
-
Wise, D. R., Ward, P. S., Shay, J. E., Cross, J. R., Gruber, J. J., Sachdeva, U. M., et al. (2011). Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of alpha-ketoglutarate to citrate to support cell growth and viability. Proc. Natl. Acad. Sci. U.S.A. 108, 19611-19616.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 19611-19616
-
-
Wise, D.R.1
Ward, P.S.2
Shay, J.E.3
Cross, J.R.4
Gruber, J.J.5
Sachdeva, U.M.6
-
60
-
-
0030014489
-
Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation
-
Xu, X., Williams, J. W., Gong, H., Finnegan, A., and Chong, A. S. (1996). Two activities of the immunosuppressive metabolite of leflunomide, A77 1726. Inhibition of pyrimidine nucleotide synthesis and protein tyrosine phosphorylation. Biochem. Pharmacol. 52, 527-534.
-
(1996)
Biochem. Pharmacol.
, vol.52
, pp. 527-534
-
-
Xu, X.1
Williams, J.W.2
Gong, H.3
Finnegan, A.4
Chong, A.S.5
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