A respiratory chain controlled signal transduction cascade in the mitochondrial intermembrane space mediates hydrogen peroxide signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 42, 2015, Pages E5679-E5688

  Patterson, Heide Christine ^a,b,c,d   Gerbeth, Carolin ^e   Thiru, Prathapan ^a   Vögtle, Nora F ^e   Knoll, Marko ^a   Shahsafaei, Aliakbar ^b   Samocha, Kaitlin E ^f,g   Huang, Cher X ^a   Harden, Mark Michael ^a   Song, Rui ^a   Chen, Cynthia ^a   Kao, Jennifer ^a   Shi, Jiahai ^a   Salmon, Wendy ^a   Shaul, Yoav D ^a   Stokes, Matthew P ^h   Silva, Jeffrey C ^h   Bell, George W ^a   MacArthur, Daniel G ^f,g   Ruland, Jürgen ^d   Meisinger, Chris ^e   Lodish, Harvey F ^a,i   more..

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c LABORATORY FOR MOLECULAR MEDICINE   (United States)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF FREIBURG   (Germany)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^h CELL SIGNALING TECHNOLOGY   (United States)

ⁱ MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Btk; Dasatinib; Fostamatinib; PTPN6; Rotenone

Indexed keywords

DASATINIB; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; OLIGOMYCIN; PHOSPHOLIPASE C GAMMA2; PROTEIN KINASE B; PROTEIN KINASE LYN; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; ROTENONE; STRESS ACTIVATED PROTEIN KINASE; TYROSINE PROTEIN KINASE BTK; UNCLASSIFIED DRUG; VANADATE SODIUM; REACTIVE OXYGEN METABOLITE; SIGNAL PEPTIDE; SYK PROTEIN, HUMAN; SYK PROTEIN, MOUSE; TYROSINE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; B LYMPHOCYTE; CALCIUM TRANSPORT; CANCER INHIBITION; CELL CYCLE REGULATION; CELL DEATH; CONFERENCE PAPER; EMBRYO; ENZYME PHOSPHORYLATION; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; RESPIRATORY CHAIN; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CHICKEN; ELECTRON TRANSPORT; ENZYME ACTIVATION; METABOLISM; PHOSPHORYLATION;

ANIMALS; CELLS, CULTURED; CHICKENS; ELECTRON TRANSPORT; ENZYME ACTIVATION; HYDROGEN PEROXIDE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MITOCHONDRIAL MEMBRANES; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SYK KINASE; TYROSINE;

EID: 84945566427     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1517932112     Document Type: Article

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