-
1
-
-
0030067819
-
A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes
-
Devergne O, Hummel M, Koeppen H, Le Beau MM, Nathanson EC, Kieff E, Birkenbach M. A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes. J Virol. 1996;70(2):1143-53.
-
(1996)
J Virol
, vol.70
, Issue.2
, pp. 1143-1153
-
-
Devergne, O.1
Hummel, M.2
Koeppen, H.3
Le Beau, M.M.4
Nathanson, E.C.5
Kieff, E.6
Birkenbach, M.7
-
2
-
-
0030700003
-
Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin
-
Devergne O, Birkenbach M, Kieff E. Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin. Proc Natl Acad Sci U S A. 1997;94(22):12041-6.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.22
, pp. 12041-12046
-
-
Devergne, O.1
Birkenbach, M.2
Kieff, E.3
-
3
-
-
18444385868
-
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells
-
Pfl anz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, Hibbert L, Churakova T, Travis M, Vaisberg E, et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. Immunity. 2002;16(6):779-90.
-
(2002)
Immunity
, vol.16
, Issue.6
, pp. 779-790
-
-
Pfl Anz, S.1
Timans, J.C.2
Cheung, J.3
Rosales, R.4
Kanzler, H.5
Gilbert, J.6
Hibbert, L.7
Churakova, T.8
Travis, M.9
Vaisberg, E.10
-
4
-
-
33846440515
-
Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways
-
Liu J, Guan X, Ma X. Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways. J Exp Med. 2007;204(1):141-52.
-
(2007)
J Exp Med
, vol.204
, Issue.1
, pp. 141-152
-
-
Liu, J.1
Guan, X.2
Ma, X.3
-
5
-
-
20044378485
-
EBV-induced gene 3 transcription is induced by TLR signaling in primary dendritic cells via NF-kappa B activation
-
Wirtz S, Becker C, Fantini MC, Nieuwenhuis EE, Tubbe I, Galle PR, Schild HJ, Birkenbach M, Blumberg RS, Neurath MF. EBV-induced gene 3 transcription is induced by TLR signaling in primary dendritic cells via NF-kappa B activation. J Immunol. 2005;174(5):2814-24.
-
(2005)
J Immunol
, vol.174
, Issue.5
, pp. 2814-2824
-
-
Wirtz, S.1
Becker, C.2
Fantini, M.C.3
Nieuwenhuis, E.E.4
Tubbe, I.5
Galle, P.R.6
Schild, H.J.7
Birkenbach, M.8
Blumberg, R.S.9
Neurath, M.F.10
-
6
-
-
2942720565
-
Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development
-
Smits HH, van Beelen AJ, Hessle C, Westland R, de Jong E, Soeteman E, Wold A, Wierenga EA, Kapsenberg ML. Commensal Gram-negative bacteria prime human dendritic cells for enhanced IL-23 and IL-27 expression and enhanced Th1 development. Eur J Immunol. 2004;34(5):1371-80.
-
(2004)
Eur J Immunol
, vol.34
, Issue.5
, pp. 1371-1380
-
-
Smits, H.H.1
Van Beelen, A.J.2
Hessle, C.3
Westland, R.4
De Jong, E.5
Soeteman, E.6
Wold, A.7
Wierenga, E.A.8
Kapsenberg, M.L.9
-
7
-
-
2342614855
-
Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1-type cytokines and chemokines in human monocyte-derived dendritic cells
-
Veckman V, Miettinen M, Pirhonen J, Siren J, Matikainen S, Julkunen I. Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1-type cytokines and chemokines in human monocyte-derived dendritic cells. J Leukoc Biol. 2004;75(5):764-71.
-
(2004)
J Leukoc Biol
, vol.75
, Issue.5
, pp. 764-771
-
-
Veckman, V.1
Miettinen, M.2
Pirhonen, J.3
Siren, J.4
Matikainen, S.5
Julkunen, I.6
-
8
-
-
0034665759
-
Identification of genes specifi cally expressed in human activated and mature dendritic cells through serial analysis of gene expression
-
Hashimoto SI, Suzuki T, Nagai S, Yamashita T, Toyoda N, Matsushima K. Identification of genes specifi cally expressed in human activated and mature dendritic cells through serial analysis of gene expression. Blood. 2000;96(6):2206-14.
-
(2000)
Blood
, vol.96
, Issue.6
, pp. 2206-2214
-
-
Hashimoto, S.I.1
Suzuki, T.2
Nagai, S.3
Yamashita, T.4
Toyoda, N.5
Matsushima, K.6
-
9
-
-
77954359269
-
Activation of IL-27 p28 gene transcription by interferon regulatory factor 8 in cooperation with interferon regulatory factor 1
-
Zhang J, Qian X, Ning H, Yang J, Xiong H, Liu J. Activation of IL-27 p28 gene transcription by interferon regulatory factor 8 in cooperation with interferon regulatory factor 1. J Biol Chem. 2010;285(28):21269-81.
-
(2010)
J Biol Chem
, vol.285
, Issue.28
, pp. 21269-21281
-
-
Zhang, J.1
Qian, X.2
Ning, H.3
Yang, J.4
Xiong, H.5
Liu, J.6
-
10
-
-
79956202545
-
Transcriptional suppression of IL-27 production by Mycobacterium tuberculosis-activated p38 MAPK via inhibition of AP-1 binding
-
Zhang J, Qian X, Ning H, Eickhoff CS, Hoft DF, Liu J. Transcriptional suppression of IL-27 production by Mycobacterium tuberculosis-activated p38 MAPK via inhibition of AP-1 binding. J Immunol. 2011;186(10):5885-95.
-
(2011)
J Immunol
, vol.186
, Issue.10
, pp. 5885-5895
-
-
Zhang, J.1
Qian, X.2
Ning, H.3
Eickhoff, C.S.4
Hoft, D.F.5
Liu, J.6
-
11
-
-
84888043763
-
IFN-gamma-induced IL-27 and IL-27p28 expression are differentially regulated through JNK MAPK and PI3K pathways independent of Jak/STAT in human monocytic cells
-
Blahoianu MA, Rahimi AA, Kozlowski M, Angel JB, Kumar A. IFN-gamma-induced IL-27 and IL-27p28 expression are differentially regulated through JNK MAPK and PI3K pathways independent of Jak/STAT in human monocytic cells. Immunobiology. 2014;219(1):1-8.
-
(2014)
Immunobiology
, vol.219
, Issue.1
, pp. 1-8
-
-
Blahoianu, M.A.1
Rahimi, A.A.2
Kozlowski, M.3
Angel, J.B.4
Kumar, A.5
-
12
-
-
34250167871
-
IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3
-
Molle C, Nguyen M, Flamand V, Renneson J, Trottein F, De Wit D, Willems F, Goldman M, Goriely S. IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3. J Immunol. 2007;178(12):7607-15.
-
(2007)
J Immunol
, vol.178
, Issue.12
, pp. 7607-7615
-
-
Molle, C.1
Nguyen, M.2
Flamand, V.3
Renneson, J.4
Trottein, F.5
De Wit, D.6
Willems, F.7
Goldman, M.8
Goriely, S.9
-
13
-
-
77949891800
-
Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process
-
Molle C, Goldman M, Goriely S. Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process. J Immunol. 2010;184(4):1784-92.
-
(2010)
J Immunol
, vol.184
, Issue.4
, pp. 1784-1792
-
-
Molle, C.1
Goldman, M.2
Goriely, S.3
-
14
-
-
37549011741
-
IFN-beta modulates the response to TLR stimulation in human DC: Involvement of IFN regulatory factor-1 (IRF-1) in IL-27 gene expression
-
Remoli ME, Gafa V, Giacomini E, Severa M, Lande R, Coccia EM. IFN-beta modulates the response to TLR stimulation in human DC: involvement of IFN regulatory factor-1 (IRF-1) in IL-27 gene expression. Eur J Immunol. 2007;37(12):3499-508.
-
(2007)
Eur J Immunol
, vol.37
, Issue.12
, pp. 3499-3508
-
-
Remoli, M.E.1
Gafa, V.2
Giacomini, E.3
Severa, M.4
Lande, R.5
Coccia, E.M.6
-
15
-
-
0036890125
-
Interferon-beta differentially regulates expression of the IL-12 family members p35, p40, p19 and EBI3 in activated human dendritic cells
-
van Seventer JM, Nagai T, van Seventer GA. Interferon-beta differentially regulates expression of the IL-12 family members p35, p40, p19 and EBI3 in activated human dendritic cells. J Neuroimmunol. 2002;133(1 2):60-71.
-
(2002)
J Neuroimmunol
, vol.133
, Issue.1-2
, pp. 60-71
-
-
Van Seventer, J.M.1
Nagai, T.2
Van Seventer, G.A.3
-
16
-
-
44449146212
-
Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: Role of intracellular osteopontin
-
Shinohara ML, Kim JH, Garcia VA, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity. 2008;29(1):68-78.
-
(2008)
Immunity
, vol.29
, Issue.1
, pp. 68-78
-
-
Shinohara, M.L.1
Kim, J.H.2
Garcia, V.A.3
Cantor, H.4
-
17
-
-
84877793134
-
Tristetraprolin (TTP): Interactions with mRNA and proteins, and current thoughts on mechanisms of action
-
Brooks SA, Blackshear PJ. Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action. Biochim Biophys Acta. 2013;1829(6 7):666-79.
-
(2013)
Biochim Biophys Acta
, vol.1829
, Issue.6-7
, pp. 666-679
-
-
Brooks, S.A.1
Blackshear, P.J.2
-
18
-
-
0032495990
-
Cloning and characterization of a novel class I cytokine receptor
-
Sprecher CA, Grant FJ, Baumgartner JW, Presnell SR, Schrader SK, Yamagiwa T, Whitmore TE, O’Hara PJ, Foster DF. Cloning and characterization of a novel class I cytokine receptor. Biochem Biophys Res Commun. 1998;246(1):82-90.
-
(1998)
Biochem Biophys Res Commun
, vol.246
, Issue.1
, pp. 82-90
-
-
Sprecher, C.A.1
Grant, F.J.2
Baumgartner, J.W.3
Presnell, S.R.4
Schrader, S.K.5
Yamagiwa, T.6
Whitmore, T.E.7
O’Hara, P.J.8
Foster, D.F.9
-
19
-
-
10744222574
-
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
-
Pfl anz S, Hibbert L, Mattson J, Rosales R, Vaisberg E, Bazan JF, Phillips JH, McClanahan TK, de Waal MR, Kastelein RA. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J Immunol. 2004;172(4):2225-31.
-
(2004)
J Immunol
, vol.172
, Issue.4
, pp. 2225-2231
-
-
Pfl Anz, S.1
Hibbert, L.2
Mattson, J.3
Rosales, R.4
Vaisberg, E.5
Bazan, J.F.6
Phillips, J.H.7
McClanahan, T.K.8
De Waal, M.R.9
Kastelein, R.A.10
-
20
-
-
0034687402
-
Development of Th1-type immune responses requires the type I cytokine receptor TCCR
-
Chen Q, Ghilardi N, Wang H, Baker T, Xie MH, Gurney A, Grewal IS, de Sauvage FJ. Development of Th1-type immune responses requires the type I cytokine receptor TCCR. Nature. 2000;407(6806):916-20.
-
(2000)
Nature
, vol.407
, Issue.6806
, pp. 916-920
-
-
Chen, Q.1
Ghilardi, N.2
Wang, H.3
Baker, T.4
Xie, M.H.5
Gurney, A.6
Grewal, I.S.7
De Sauvage, F.J.8
-
21
-
-
36749024030
-
Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor
-
Pradhan A, Lambert QT, Reuther GW. Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor. Proc Natl Acad Sci U S A. 2007;104(47):18502-7.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.47
, pp. 18502-18507
-
-
Pradhan, A.1
Lambert, Q.T.2
Reuther, G.W.3
-
22
-
-
67650462706
-
Expression of WSX1 in tumors sensitizes IL-27 signaling-independent natural killer cell surveillance
-
Dibra D, Cutrera JJ, Xia X, Birkenbach MP, Li S. Expression of WSX1 in tumors sensitizes IL-27 signaling-independent natural killer cell surveillance. Cancer Res. 2009;69(13):5505-13.
-
(2009)
Cancer Res
, vol.69
, Issue.13
, pp. 5505-5513
-
-
Dibra, D.1
Cutrera, J.J.2
Xia, X.3
Birkenbach, M.P.4
Li, S.5
-
23
-
-
0038326688
-
Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
-
Takeda A, Hamano S, Yamanaka A, Hanada T, Ishibashi T, Mak TW, Yoshimura A, Yoshida H. Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J Immunol. 2003;170(10):4886-90.
-
(2003)
J Immunol
, vol.170
, Issue.10
, pp. 4886-4890
-
-
Takeda, A.1
Hamano, S.2
Yamanaka, A.3
Hanada, T.4
Ishibashi, T.5
Mak, T.W.6
Yoshimura, A.7
Yoshida, H.8
-
24
-
-
4644225089
-
An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells
-
Kamiya S, Owaki T, Morishima N, Fukai F, Mizuguchi J, Yoshimoto T. An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells. J Immunol. 2004;173(6):3871-7.
-
(2004)
J Immunol
, vol.173
, Issue.6
, pp. 3871-3877
-
-
Kamiya, S.1
Owaki, T.2
Morishima, N.3
Fukai, F.4
Mizuguchi, J.5
Yoshimoto, T.6
-
25
-
-
20444375878
-
Positive and negative regulation of the IL-27 receptor during lymphoid cell activation
-
Villarino AV, Larkin 3rd J, Saris CJ, Caton AJ, Lucas S, Wong T, de Sauvage FJ, Hunter CA. Positive and negative regulation of the IL-27 receptor during lymphoid cell activation. J Immunol. 2005;174(12):7684-91.
-
(2005)
J Immunol
, vol.174
, Issue.12
, pp. 7684-7691
-
-
Villarino, A.V.1
Larkin, J.2
Saris, C.J.3
Caton, A.J.4
Lucas, S.5
Wong, T.6
De Sauvage, F.J.7
Hunter, C.A.8
-
26
-
-
17944377950
-
WSX-1 is required for the initiation of Th1 responses and resistance to L. Major infection
-
Yoshida H, Hamano S, Senaldi G, Covey T, Faggioni R, Mu S, Xia M, Wakeham AC, Nishina H, Potter J, et al. WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection. Immunity. 2001;15(4):569-78.
-
(2001)
Immunity
, vol.15
, Issue.4
, pp. 569-578
-
-
Yoshida, H.1
Hamano, S.2
Senaldi, G.3
Covey, T.4
Faggioni, R.5
Mu, S.6
Xia, M.7
Wakeham, A.C.8
Nishina, H.9
Potter, J.10
-
27
-
-
1842477302
-
Cutting edge: Early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection
-
Artis D, Johnson LM, Joyce K, Saris C, Villarino A, Hunter CA, Scott P. Cutting edge: early IL-4 production governs the requirement for IL-27-WSX-1 signaling in the development of protective Th1 cytokine responses following Leishmania major infection. J Immunol. 2004;172(8):4672-5.
-
(2004)
J Immunol
, vol.172
, Issue.8
, pp. 4672-4675
-
-
Artis, D.1
Johnson, L.M.2
Joyce, K.3
Saris, C.4
Villarino, A.5
Hunter, C.A.6
Scott, P.7
-
28
-
-
33751568890
-
IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways
-
Owaki T, Asakawa M, Fukai F, Mizuguchi J, Yoshimoto T. IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol. 2006;177(11):7579-87.
-
(2006)
J Immunol
, vol.177
, Issue.11
, pp. 7579-7587
-
-
Owaki, T.1
Asakawa, M.2
Fukai, F.3
Mizuguchi, J.4
Yoshimoto, T.5
-
29
-
-
0345570521
-
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
-
Villarino A, Hibbert L, Lieberman L, Wilson E, Mak T, Yoshida H, Kastelein RA, Saris C, Hunter CA. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity. 2003;19(5):645-55.
-
(2003)
Immunity
, vol.19
, Issue.5
, pp. 645-655
-
-
Villarino, A.1
Hibbert, L.2
Lieberman, L.3
Wilson, E.4
Mak, T.5
Yoshida, H.6
Kastelein, R.A.7
Saris, C.8
Hunter, C.A.9
-
30
-
-
10744221849
-
WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinfl ammatory cytokine production
-
Hamano S, Himeno K, Miyazaki Y, Ishii K, Yamanaka A, Takeda A, Zhang M, Hisaeda H, Mak TW, Yoshimura A, et al. WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinfl ammatory cytokine production. Immunity. 2003;19(5):657-67.
-
(2003)
Immunity
, vol.19
, Issue.5
, pp. 657-667
-
-
Hamano, S.1
Himeno, K.2
Miyazaki, Y.3
Ishii, K.4
Yamanaka, A.5
Takeda, A.6
Zhang, M.7
Hisaeda, H.8
Mak, T.W.9
Yoshimura, A.10
-
31
-
-
30344488706
-
Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-defi cient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology
-
Rosas LE, Satoskar AA, Roth KM, Keiser TL, Barbi J, Hunter C, de Sauvage FJ, Satoskar AR. Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-defi cient mice display enhanced resistance to leishmania donovani infection but develop severe liver immunopathology. Am J Pathol. 2006;168(1):158-69.
-
(2006)
Am J Pathol
, vol.168
, Issue.1
, pp. 158-169
-
-
Rosas, L.E.1
Satoskar, A.A.2
Roth, K.M.3
Keiser, T.L.4
Barbi, J.5
Hunter, C.6
De Sauvage, F.J.7
Satoskar, A.R.8
-
32
-
-
77956899787
-
Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection
-
Findlay EG, Greig R, Stumhofer JS, Hafalla JC, de Souza JB, Saris CJ, Hunter CA, Riley EM, Couper KN. Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection. J Immunol. 2010;185(4):2482-92.
-
(2010)
J Immunol
, vol.185
, Issue.4
, pp. 2482-2492
-
-
Findlay, E.G.1
Greig, R.2
Stumhofer, J.S.3
Hafalla, J.C.4
De Souza, J.B.5
Saris, C.J.6
Hunter, C.A.7
Riley, E.M.8
Couper, K.N.9
-
33
-
-
84876793137
-
IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals
-
Villegas-Mendez A, de Souza JB, Lavelle SW, Gwyer Findlay E, Shaw TN, van Rooijen N, Saris CJ, Hunter CA, Riley EM, Couper KN. IL-27 receptor signalling restricts the formation of pathogenic, terminally differentiated Th1 cells during malaria infection by repressing IL-12 dependent signals. PLoS Pathog. 2013;9(4):e1003293.
-
(2013)
Plos Pathog
, vol.9
, Issue.4
-
-
Villegas-Mendez, A.1
De Souza, J.B.2
Lavelle, S.W.3
Gwyer Findlay, E.4
Shaw, T.N.5
Van Rooijen, N.6
Saris, C.J.7
Hunter, C.A.8
Riley, E.M.9
Couper, K.N.10
-
34
-
-
29644443883
-
IL-27 limits IL-2 production during Th1 differentiation
-
Villarino AV, Stumhofer JS, Saris CJ, Kastelein RA, de Sauvage FJ, Hunter CA. IL-27 limits IL-2 production during Th1 differentiation. J Immunol. 2006;176(1):237-47.
-
(2006)
J Immunol
, vol.176
, Issue.1
, pp. 237-247
-
-
Villarino, A.V.1
Stumhofer, J.S.2
Saris, C.J.3
Kastelein, R.A.4
De Sauvage, F.J.5
Hunter, C.A.6
-
35
-
-
33644536099
-
IL-27 suppresses CD28-mediated [correction of medicated] IL-2 production through suppressor of cytokine signaling 3
-
Owaki T, Asakawa M, Kamiya S, Takeda K, Fukai F, Mizuguchi J, Yoshimoto T. IL-27 suppresses CD28-mediated [correction of medicated] IL-2 production through suppressor of cytokine signaling 3. J Immunol. 2006;176(5):2773-80.
-
(2006)
J Immunol
, vol.176
, Issue.5
, pp. 2773-2780
-
-
Owaki, T.1
Asakawa, M.2
Kamiya, S.3
Takeda, K.4
Fukai, F.5
Mizuguchi, J.6
Yoshimoto, T.7
-
36
-
-
36248970702
-
Suppression of autoimmune infl ammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
-
Fitzgerald DC, Zhang GX, El-Behi M, Fonseca-Kelly Z, Li H, Yu S, Saris CJ, Gran B, Ciric B, Rostami A. Suppression of autoimmune infl ammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat Immunol. 2007;8(12):1372-9.
-
(2007)
Nat Immunol
, vol.8
, Issue.12
, pp. 1372-1379
-
-
Fitzgerald, D.C.1
Zhang, G.X.2
El-Behi, M.3
Fonseca-Kelly, Z.4
Li, H.5
Yu, S.6
Saris, C.J.7
Gran, B.8
Ciric, B.9
Rostami, A.10
-
37
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer JS, Silver JS, Laurence A, Porrett PM, Harris TH, Turka LA, Ernst M, Saris CJ, O’Shea JJ, Hunter CA. Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat Immunol. 2007;8(12):1363-71.
-
(2007)
Nat Immunol
, vol.8
, Issue.12
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Harris, T.H.5
Turka, L.A.6
Ernst, M.7
Saris, C.J.8
O’Shea, J.J.9
Hunter, C.A.10
-
38
-
-
79952994082
-
CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs
-
Sun J, Dodd H, Moser EK, Sharma R, Braciale TJ. CD4+ T cell help and innate-derived IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs. Nat Immunol. 2011;12(4):327-34.
-
(2011)
Nat Immunol
, vol.12
, Issue.4
, pp. 327-334
-
-
Sun, J.1
Dodd, H.2
Moser, E.K.3
Sharma, R.4
Braciale, T.J.5
-
39
-
-
49149119535
-
Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells
-
Batten M, Kljavin NM, Li J, Walter MJ, de Sauvage FJ, Ghilardi N. Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells. J Immunol. 2008;180(5):2752-6.
-
(2008)
J Immunol
, vol.180
, Issue.5
, pp. 2752-2756
-
-
Batten, M.1
Kljavin, N.M.2
Li, J.3
Walter, M.J.4
De Sauvage, F.J.5
Ghilardi, N.6
-
40
-
-
84906534462
-
Role of Blimp-1 in programming Th effector cells into IL-10 producers
-
Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi MF, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kuhl AA, et al. Role of Blimp-1 in programming Th effector cells into IL-10 producers. J Exp Med. 2014;211(9):1807-19.
-
(2014)
J Exp Med
, vol.211
, Issue.9
, pp. 1807-1819
-
-
Neumann, C.1
Heinrich, F.2
Neumann, K.3
Junghans, V.4
Mashreghi, M.F.5
Ahlers, J.6
Janke, M.7
Rudolph, C.8
Mockel-Tenbrinck, N.9
Kuhl, A.A.10
-
41
-
-
6344274850
-
The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity
-
Artis D, Villarino A, Silverman M, He W, Thornton EM, Mu S, Summer S, Covey TM, Huang E, Yoshida H, et al. The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. J Immunol. 2004;173(9):5626-34.
-
(2004)
J Immunol
, vol.173
, Issue.9
, pp. 5626-5634
-
-
Artis, D.1
Villarino, A.2
Silverman, M.3
He, W.4
Thornton, E.M.5
Mu, S.6
Summer, S.7
Covey, T.M.8
Huang, E.9
Yoshida, H.10
-
42
-
-
0344304399
-
IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms
-
Lucas S, Ghilardi N, Li J, de Sauvage FJ. IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms. Proc Natl Acad Sci U S A. 2003;100(25):15047-52.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.25
, pp. 15047-15052
-
-
Lucas, S.1
Ghilardi, N.2
Li, J.3
De Sauvage, F.J.4
-
43
-
-
38149045608
-
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: A novel therapeutic way for Th2-mediated allergic infl ammation
-
Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K. IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic infl ammation. J Immunol. 2007;179(7):4415-23.
-
(2007)
J Immunol
, vol.179
, Issue.7
, pp. 4415-4423
-
-
Yoshimoto, T.1
Yoshimoto, T.2
Yasuda, K.3
Mizuguchi, J.4
Nakanishi, K.5
-
44
-
-
79952535373
-
EBI3 deficiency leads to diminished T helper type 1 and increased T helper type 2 mediated airway inflammation
-
Dokmeci E, Xu L, Robinson E, Golubets K, Bottomly K, Herrick CA. EBI3 deficiency leads to diminished T helper type 1 and increased T helper type 2 mediated airway inflammation. Immunology. 2011;132(4):559-66.
-
(2011)
Immunology
, vol.132
, Issue.4
, pp. 559-566
-
-
Dokmeci, E.1
Xu, L.2
Robinson, E.3
Golubets, K.4
Bottomly, K.5
Herrick, C.A.6
-
45
-
-
70350015398
-
Non-redundant role for IL-12 and IL-27 in modulating Th2 polarization of carcinoembryonic antigen specific CD4 T cells from pancreatic cancer patients
-
Tassi E, Braga M, Longhi R, Gavazzi F, Parmiani G, Di Carlo V, Protti MP. Non-redundant role for IL-12 and IL-27 in modulating Th2 polarization of carcinoembryonic antigen specific CD4 T cells from pancreatic cancer patients. PLoS One. 2009;4(10):e7234.
-
(2009)
Plos One
, vol.4
, Issue.10
-
-
Tassi, E.1
Braga, M.2
Longhi, R.3
Gavazzi, F.4
Parmiani, G.5
Di Carlo, V.6
Protti, M.P.7
-
47
-
-
84869806031
-
IFN-gamma limits Th9-mediated autoimmune infl ammation through dendritic cell modulation of IL-27
-
Murugaiyan G, Beynon V, Pires Da Cunha A, Joller N, Weiner HL. IFN-gamma limits Th9-mediated autoimmune infl ammation through dendritic cell modulation of IL-27. J Immunol. 2012;189(11):5277-83.
-
(2012)
J Immunol
, vol.189
, Issue.11
, pp. 5277-5283
-
-
Murugaiyan, G.1
Beynon, V.2
Pires Da Cunha, A.3
Joller, N.4
Weiner, H.L.5
-
48
-
-
39049152572
-
IL-27 inhibits the development of regulatory T cells via STAT3
-
Huber M, Steinwald V, Guralnik A, Brustle A, Kleemann P, Rosenplanter C, Decker T, Lohoff M. IL-27 inhibits the development of regulatory T cells via STAT3. Int Immunol. 2008;20(2):223-34.
-
(2008)
Int Immunol
, vol.20
, Issue.2
, pp. 223-234
-
-
Huber, M.1
Steinwald, V.2
Guralnik, A.3
Brustle, A.4
Kleemann, P.5
Rosenplanter, C.6
Decker, T.7
Lohoff, M.8
-
49
-
-
79960400849
-
A role for IL-27 in limiting T regulatory cell populations
-
Wojno ED, Hosken N, Stumhofer JS, O’Hara AC, Mauldin E, Fang Q, Turka LA, Levin SD, Hunter CA. A role for IL-27 in limiting T regulatory cell populations. J Immunol. 2011;187(1):266-73.
-
(2011)
J Immunol
, vol.187
, Issue.1
, pp. 266-273
-
-
Wojno, E.D.1
Hosken, N.2
Stumhofer, J.S.3
O’Hara, A.C.4
Mauldin, E.5
Fang, Q.6
Turka, L.A.7
Levin, S.D.8
Hunter, C.A.9
-
50
-
-
78651492594
-
IL-27 promotes T cell-dependent colitis through multiple mechanisms
-
Cox JH, Kljavin NM, Ramamoorthi N, Diehl L, Batten M, Ghilardi N. IL-27 promotes T cell-dependent colitis through multiple mechanisms. J Exp Med. 2011;208(1):115-23.
-
(2011)
J Exp Med
, vol.208
, Issue.1
, pp. 115-123
-
-
Cox, J.H.1
Kljavin, N.M.2
Ramamoorthi, N.3
Diehl, L.4
Batten, M.5
Ghilardi, N.6
-
51
-
-
84866483591
-
The cytokines interleukin 27 and interferon-gamma promote distinct Treg cell populations required to limit infection-induced pathology
-
Hall AO, Beiting DP, Tato C, John B, Oldenhove G, Lombana CG, Pritchard GH, Silver JS, Bouladoux N, Stumhofer JS, et al. The cytokines interleukin 27 and interferon-gamma promote distinct Treg cell populations required to limit infection-induced pathology. Immunity. 2012;37(3):511-23.
-
(2012)
Immunity
, vol.37
, Issue.3
, pp. 511-523
-
-
Hall, A.O.1
Beiting, D.P.2
Tato, C.3
John, B.4
Oldenhove, G.5
Lombana, C.G.6
Pritchard, G.H.7
Silver, J.S.8
Bouladoux, N.9
Stumhofer, J.S.10
-
52
-
-
69249083836
-
Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
-
Pot C, Jin H, Awasthi A, Liu SM, Lai CY, Madan R, Sharpe AH, Karp CL, Miaw SC, Ho IC, et al. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J Immunol. 2009;183(2):797-801.
-
(2009)
J Immunol
, vol.183
, Issue.2
, pp. 797-801
-
-
Pot, C.1
Jin, H.2
Awasthi, A.3
Liu, S.M.4
Lai, C.Y.5
Madan, R.6
Sharpe, A.H.7
Karp, C.L.8
Miaw, S.C.9
Ho, I.C.10
-
53
-
-
73249149628
-
C-Maf regulates IL-10 expression during Th17 polarization
-
Xu J, Yang Y, Qiu G, Lal G, Wu Z, Levy DE, Ochando JC, Bromberg JS, Ding Y. c-Maf regulates IL-10 expression during Th17 polarization. J Immunol. 2009;182(10):6226-36.
-
(2009)
J Immunol
, vol.182
, Issue.10
, pp. 6226-6236
-
-
Xu, J.1
Yang, Y.2
Qiu, G.3
Lal, G.4
Wu, Z.5
Levy, D.E.6
Ochando, J.C.7
Bromberg, J.S.8
Ding, Y.9
-
54
-
-
82755160805
-
Induction of regulatory Tr1 cells and inhibition of T(H)17 cells by IL-27
-
Pot C, Apetoh L, Awasthi A, Kuchroo VK. Induction of regulatory Tr1 cells and inhibition of T(H)17 cells by IL-27. Semin Immunol. 2011;23(6):438-45.
-
(2011)
Semin Immunol
, vol.23
, Issue.6
, pp. 438-445
-
-
Pot, C.1
Apetoh, L.2
Awasthi, A.3
Kuchroo, V.K.4
-
55
-
-
79955064497
-
Treatment with IL-27 attenuates experimental colitis through the suppression of the development of IL-17-producing T helper cells
-
Sasaoka T, Ito M, Yamashita J, Nakajima K, Tanaka I, Narita M, Hara Y, Hada K, Takahashi M, Ohno Y, et al. Treatment with IL-27 attenuates experimental colitis through the suppression of the development of IL-17-producing T helper cells. Am J Physiol Gastrointest Liver Physiol. 2011;300(4):G568-76.
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
, Issue.4
, pp. G568-G576
-
-
Sasaoka, T.1
Ito, M.2
Yamashita, J.3
Nakajima, K.4
Tanaka, I.5
Narita, M.6
Hara, Y.7
Hada, K.8
Takahashi, M.9
Ohno, Y.10
-
56
-
-
78650671831
-
STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and-independent mechanisms
-
Villarino AV, Gallo E, Abbas AK. STAT1-activating cytokines limit Th17 responses through both T-bet-dependent and-independent mechanisms. J Immunol. 2010;185(11):6461-71.
-
(2010)
J Immunol
, vol.185
, Issue.11
, pp. 6461-6471
-
-
Villarino, A.V.1
Gallo, E.2
Abbas, A.K.3
-
57
-
-
70149105112
-
IL-27 is a key regulator of IL-10 and IL-17 production by human CD4+ T cells
-
Murugaiyan G, Mittal A, Lopez-Diego R, Maier LM, Anderson DE, Weiner HL. IL-27 is a key regulator of IL-10 and IL-17 production by human CD4+ T cells. J Immunol. 2009;183(4):2435-43.
-
(2009)
J Immunol
, vol.183
, Issue.4
, pp. 2435-2443
-
-
Murugaiyan, G.1
Mittal, A.2
Lopez-Diego, R.3
Maier, L.M.4
Erson, D.E.5
Weiner, H.L.6
-
58
-
-
33749515631
-
Two-sided roles of IL-27: Induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinfl ammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism
-
Yoshimura T, Takeda A, Hamano S, Miyazaki Y, Kinjyo I, Ishibashi T, Yoshimura A, Yoshida H. Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinfl ammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism. J Immunol. 2006;177(8):5377-85.
-
(2006)
J Immunol
, vol.177
, Issue.8
, pp. 5377-5385
-
-
Yoshimura, T.1
Takeda, A.2
Hamano, S.3
Miyazaki, Y.4
Kinjyo, I.5
Ishibashi, T.6
Yoshimura, A.7
Yoshida, H.8
-
59
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
-
Batten M, Li J, Yi S, Kljavin NM, Danilenko DM, Lucas S, Lee J, de Sauvage FJ, Ghilardi N. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Immunol. 2006;7(9):929-36.
-
(2006)
Nat Immunol
, vol.7
, Issue.9
, pp. 929-936
-
-
Batten, M.1
Li, J.2
Yi, S.3
Kljavin, N.M.4
Danilenko, D.M.5
Lucas, S.6
Lee, J.7
De Sauvage, F.J.8
Ghilardi, N.9
-
60
-
-
78650357814
-
IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells
-
Batten M, Ramamoorthi N, Kljavin NM, Ma CS, Cox JH, Dengler HS, Danilenko DM, Caplazi P, Wong M, Fulcher DA, et al. IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells. J Exp Med. 2010;207(13):2895-906.
-
(2010)
J Exp Med
, vol.207
, Issue.13
, pp. 2895-2906
-
-
Batten, M.1
Ramamoorthi, N.2
Kljavin, N.M.3
Ma, C.S.4
Cox, J.H.5
Dengler, H.S.6
Danilenko, D.M.7
Caplazi, P.8
Wong, M.9
Fulcher, D.A.10
-
61
-
-
84863297929
-
Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells
-
Liu L, Meng J, Zhang C, Duan Y, Zhao L, Wang S, Shan B. Effects on apoptosis and cell cycle arrest contribute to the antitumor responses of interleukin-27 mediated by retrovirus in human pancreatic carcinoma cells. Oncol Rep. 2012;27(5):1497-503.
-
(2012)
Oncol Rep
, vol.27
, Issue.5
, pp. 1497-1503
-
-
Liu, L.1
Meng, J.2
Zhang, C.3
Duan, Y.4
Zhao, L.5
Wang, S.6
Shan, B.7
-
62
-
-
84924049544
-
IL-27 alleviates the bleomycin-induced pulmonary fi brosis by regulating the Th17 cell differentiation
-
Dong Z, Lu X, Yang Y, Zhang T, Li Y, Chai Y, Lei W, Li C, Ai L, Tai W. IL-27 alleviates the bleomycin-induced pulmonary fi brosis by regulating the Th17 cell differentiation. BMC Pulm Med. 2015;15:13.
-
(2015)
BMC Pulm Med
, vol.15
, pp. 13
-
-
Dong, Z.1
Lu, X.2
Yang, Y.3
Zhang, T.4
Li, Y.5
Chai, Y.6
Lei, W.7
Li, C.8
Ai, L.9
Tai, W.10
-
63
-
-
84865412454
-
Cutting edge: Suppression of GM-CSF expression in murine and human T cells by IL-27
-
Young A, Linehan E, Hams E, O’Hara Hall AC, McClurg A, Johnston JA, Hunter CA, Fallon PG, Fitzgerald DC. Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27. J Immunol. 2012;189(5):2079-83.
-
(2012)
J Immunol
, vol.189
, Issue.5
, pp. 2079-2083
-
-
Young, A.1
Linehan, E.2
Hams, E.3
O’Hara Hall, A.C.4
McClurg, A.5
Johnston, J.A.6
Hunter, C.A.7
Fallon, P.G.8
Fitzgerald, D.C.9
-
64
-
-
84877045985
-
IL-27 inhibits HIV-1 infection in human macrophages by downregulating host factor SPTBN1 during monocyte to macrophage differentiation
-
Dai L, Lidie KB, Chen Q, Adelsberger JW, Zheng X, Huang D, Yang J, Lempicki RA, Rehman T, Dewar RL, et al. IL-27 inhibits HIV-1 infection in human macrophages by downregulating host factor SPTBN1 during monocyte to macrophage differentiation. J Exp Med. 2013;210(3):517-34.
-
(2013)
J Exp Med
, vol.210
, Issue.3
, pp. 517-534
-
-
Dai, L.1
Lidie, K.B.2
Chen, Q.3
Adelsberger, J.W.4
Zheng, X.5
Huang, D.6
Yang, J.7
Lempicki, R.A.8
Rehman, T.9
Dewar, R.L.10
-
65
-
-
77953023296
-
Differential effect of IL-27 on developing versus committed Th17 cells
-
El-behi M, Ciric B, Yu S, Zhang GX, Fitzgerald DC, Rostami A. Differential effect of IL-27 on developing versus committed Th17 cells. J Immunol. 2009;183(8):4957-67.
-
(2009)
J Immunol
, vol.183
, Issue.8
, pp. 4957-4967
-
-
El-Behi, M.1
Ciric, B.2
Yu, S.3
Zhang, G.X.4
Fitzgerald, D.C.5
Rostami, A.6
-
66
-
-
3142724732
-
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
-
Bettelli E, Sullivan B, Szabo SJ, Sobel RA, Glimcher LH, Kuchroo VK. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J Exp Med. 2004;200(1):79-87.
-
(2004)
J Exp Med
, vol.200
, Issue.1
, pp. 79-87
-
-
Bettelli, E.1
Sullivan, B.2
Szabo, S.J.3
Sobel, R.A.4
Glimcher, L.H.5
Kuchroo, V.K.6
-
67
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005;6(11):1123-32.
-
(2005)
Nat Immunol
, vol.6
, Issue.11
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
68
-
-
84862981070
-
Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1
-
Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciume G, Hall AO, Dupont CD, Francisco LM, et al. Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1. Immunity. 2012;36(6):1017-30.
-
(2012)
Immunity
, vol.36
, Issue.6
, pp. 1017-1030
-
-
Hirahara, K.1
Ghoreschi, K.2
Yang, X.P.3
Takahashi, H.4
Laurence, A.5
Vahedi, G.6
Sciume, G.7
Hall, A.O.8
Dupont, C.D.9
Francisco, L.M.10
-
69
-
-
46749151286
-
Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
-
Nurieva RI, Chung Y, Hwang D, Yang XO, Kang HS, Ma L, Wang YH, Watowich SS, Jetten AM, Tian Q, et al. Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages. Immunity. 2008;29(1):138-49.
-
(2008)
Immunity.
, vol.29
, Issue.1
, pp. 138-149
-
-
Nurieva, R.I.1
Chung, Y.2
Hwang, D.3
Yang, X.O.4
Kang, H.S.5
Ma, L.6
Wang, Y.H.7
Watowich, S.S.8
Jetten, A.M.9
Tian, Q.10
-
70
-
-
69249101229
-
Bcl6 mediates the development of T follicular helper cells
-
Nurieva RI, Chung Y, Martinez GJ, Yang XO, Tanaka S, Matskevitch TD, Wang YH, Dong C. Bcl6 mediates the development of T follicular helper cells. Science. 2009;325(5943):1001-5.
-
(2009)
Science
, vol.325
, Issue.5943
, pp. 1001-1005
-
-
Nurieva, R.I.1
Chung, Y.2
Martinez, G.J.3
Yang, X.O.4
Tanaka, S.5
Matskevitch, T.D.6
Wang, Y.H.7
Dong, C.8
-
71
-
-
84921900452
-
Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production
-
Gringhuis SI, Kaptein TM, Wevers BA, van der Vlist M, Klaver EJ, van Die I, Vriend LE, de Jong MA, Geijtenbeek TB. Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production. Nat Commun. 2014;5:5074.
-
(2014)
Nat Commun
, vol.5
, pp. 5074
-
-
Gringhuis, S.I.1
Kaptein, T.M.2
Wevers, B.A.3
Van Der Vlist, M.4
Klaver, E.J.5
Van Die, I.6
Vriend, L.E.7
De Jong, M.A.8
Geijtenbeek, T.B.9
-
72
-
-
22544433708
-
Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27
-
Morishima N, Owaki T, Asakawa M, Kamiya S, Mizuguchi J, Yoshimoto T. Augmentation of effector CD8+ T cell generation with enhanced granzyme B expression by IL-27. J Immunol. 2005;175(3):1686-93.
-
(2005)
J Immunol
, vol.175
, Issue.3
, pp. 1686-1693
-
-
Morishima, N.1
Owaki, T.2
Asakawa, M.3
Kamiya, S.4
Mizuguchi, J.5
Yoshimoto, T.6
-
73
-
-
84866366930
-
IL-27 induction of IL-21 from human CD8+ T cells induces granzyme B in an autocrine manner
-
Mittal A, Murugaiyan G, Beynon V, Hu D, Weiner HL. IL-27 induction of IL-21 from human CD8+ T cells induces granzyme B in an autocrine manner. Immunol Cell Biol. 2012;90(8):831-5.
-
(2012)
Immunol Cell Biol
, vol.90
, Issue.8
, pp. 831-835
-
-
Mittal, A.1
Murugaiyan, G.2
Beynon, V.3
Hu, D.4
Weiner, H.L.5
-
74
-
-
78650338317
-
IL-27 increases the proliferation and effector functions of human naive CD8+ T lymphocytes and promotes their development into Tc1 cells
-
Schneider R, Yaneva T, Beauseigle D, El-Khoury L, Arbour N. IL-27 increases the proliferation and effector functions of human naive CD8+ T lymphocytes and promotes their development into Tc1 cells. Eur J Immunol. 2011;41(1):47-59.
-
(2011)
Eur J Immunol
, vol.41
, Issue.1
, pp. 47-59
-
-
Schneider, R.1
Yaneva, T.2
Beauseigle, D.3
El-Khoury, L.4
Arbour, N.5
-
75
-
-
4143098128
-
Adjuvant activities of novel cytokines, interleukin-23 (IL-23) and IL-27, for induction of hepatitis C virus-specifi c cytotoxic T lymphocytes in HLA-A*0201 transgenic mice
-
Matsui M, Moriya O, Belladonna ML, Kamiya S, Lemonnier FA, Yoshimoto T, Akatsuka T. Adjuvant activities of novel cytokines, interleukin-23 (IL-23) and IL-27, for induction of hepatitis C virus-specifi c cytotoxic T lymphocytes in HLA-A*0201 transgenic mice. J Virol. 2004;78(17):9093-104.
-
(2004)
J Virol
, vol.78
, Issue.17
, pp. 9093-9104
-
-
Matsui, M.1
Moriya, O.2
Belladonna, M.L.3
Kamiya, S.4
Lemonnier, F.A.5
Yoshimoto, T.6
Akatsuka, T.7
-
76
-
-
84912077479
-
IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization
-
Pennock ND, Gapin L, Kedl RM. IL-27 is required for shaping the magnitude, affinity distribution, and memory of T cells responding to subunit immunization. Proc Natl Acad Sci U S A. 2014;111(46):16472-7.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, Issue.46
, pp. 16472-16477
-
-
Pennock, N.D.1
Gapin, L.2
Kedl, R.M.3
-
77
-
-
0842347431
-
Potent antitumor activity of interleukin-27
-
Hisada M, Kamiya S, Fujita K, Belladonna ML, Aoki T, Koyanagi Y, Mizuguchi J, Yoshimoto T. Potent antitumor activity of interleukin-27. Cancer Res. 2004;64(3):1152-6.
-
(2004)
Cancer Res
, vol.64
, Issue.3
, pp. 1152-1156
-
-
Hisada, M.1
Kamiya, S.2
Fujita, K.3
Belladonna, M.L.4
Aoki, T.5
Koyanagi, Y.6
Mizuguchi, J.7
Yoshimoto, T.8
-
78
-
-
18644381517
-
Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals
-
Chiyo M, Shimozato O, Yu L, Kawamura K, Iizasa T, Fujisawa T, Tagawa M. Expression of IL-27 in murine carcinoma cells produces antitumor effects and induces protective immunity in inoculated host animals. Int J Cancer. 2005;115(3):437-42.
-
(2005)
Int J Cancer
, vol.115
, Issue.3
, pp. 437-442
-
-
Chiyo, M.1
Shimozato, O.2
Yu, L.3
Kawamura, K.4
Iizasa, T.5
Fujisawa, T.6
Tagawa, M.7
-
79
-
-
10344228778
-
IL-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors: Role for CD8+ T cells
-
Salcedo R, Stauffer JK, Lincoln E, Back TC, Hixon JA, Hahn C, Shafer-Weaver K, Malyguine A, Kastelein R, Wigginton JM. IL-27 mediates complete regression of orthotopic primary and metastatic murine neuroblastoma tumors: role for CD8+ T cells. J Immunol. 2004;173(12):7170-82.
-
(2004)
J Immunol
, vol.173
, Issue.12
, pp. 7170-7182
-
-
Salcedo, R.1
Stauffer, J.K.2
Lincoln, E.3
Back, T.C.4
Hixon, J.A.5
Hahn, C.6
Shafer-Weaver, K.7
Malyguine, A.8
Kastelein, R.9
Wigginton, J.M.10
-
80
-
-
4043122529
-
Induction of IgG2a class switching in B cells by IL-27
-
Yoshimoto T, Okada K, Morishima N, Kamiya S, Owaki T, Asakawa M, Iwakura Y, Fukai F, Mizuguchi J. Induction of IgG2a class switching in B cells by IL-27. J Immunol. 2004;173(4):2479-85.
-
(2004)
J Immunol
, vol.173
, Issue.4
, pp. 2479-2485
-
-
Yoshimoto, T.1
Okada, K.2
Morishima, N.3
Kamiya, S.4
Owaki, T.5
Asakawa, M.6
Iwakura, Y.7
Fukai, F.8
Mizuguchi, J.9
-
81
-
-
33646467806
-
Differential effects of IL-27 on human B cell subsets
-
Larousserie F, Charlot P, Bardel E, Froger J, Kastelein RA, Devergne O. Differential effects of IL-27 on human B cell subsets. J Immunol. 2006;176(10):5890-7.
-
(2006)
J Immunol
, vol.176
, Issue.10
, pp. 5890-5897
-
-
Larousserie, F.1
Charlot, P.2
Bardel, E.3
Froger, J.4
Kastelein, R.A.5
Devergne, O.6
-
82
-
-
84862020826
-
Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo
-
Cocco C, Di Carlo E, Zupo S, Canale S, Zorzoli A, Ribatti D, Morandi F, Ognio E, Airoldi I. Complementary IL-23 and IL-27 anti-tumor activities cause strong inhibition of human follicular and diffuse large B-cell lymphoma growth in vivo. Leukemia. 2012;26(6):1365-74.
-
(2012)
Leukemia
, vol.26
, Issue.6
, pp. 1365-1374
-
-
Cocco, C.1
Di Carlo, E.2
Zupo, S.3
Canale, S.4
Zorzoli, A.5
Ribatti, D.6
Morandi, F.7
Ognio, E.8
Airoldi, I.9
-
83
-
-
38449098843
-
Augmentation of antigen-presenting and Th1- promoting functions of dendritic cells by WSX-1(IL-27R) deficiency
-
Wang S, Miyazaki Y, Shinozaki Y, Yoshida H. Augmentation of antigen-presenting and Th1- promoting functions of dendritic cells by WSX-1(IL-27R) deficiency. J Immunol. 2007;179(10):6421-8.
-
(2007)
J Immunol
, vol.179
, Issue.10
, pp. 6421-6428
-
-
Wang, S.1
Miyazaki, Y.2
Shinozaki, Y.3
Yoshida, H.4
-
84
-
-
84886728752
-
IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39
-
Mascanfroni ID, Yeste A, Vieira SM, Burns EJ, Patel B, Sloma I, Wu Y, Mayo L, Ben-Hamo R, Efroni S, et al. IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol. 2013;14(10):1054-63.
-
(2013)
Nat Immunol
, vol.14
, Issue.10
, pp. 1054-1063
-
-
Mascanfroni, I.D.1
Yeste, A.2
Vieira, S.M.3
Burns, E.J.4
Patel, B.5
Sloma, I.6
Wu, Y.7
Mayo, L.8
Ben-Hamo, R.9
Efroni, S.10
-
85
-
-
79957851081
-
IL-27 renders DC immunosuppressive by induction of B7-H1
-
Karakhanova S, Bedke T, Enk AH, Mahnke K. IL-27 renders DC immunosuppressive by induction of B7-H1. J Leukoc Biol. 2011;89(6):837-45.
-
(2011)
J Leukoc Biol
, vol.89
, Issue.6
, pp. 837-845
-
-
Karakhanova, S.1
Bedke, T.2
Enk, A.H.3
Mahnke, K.4
-
86
-
-
84897564889
-
IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation
-
Morandi F, Di Carlo E, Ferrone S, Petretto A, Pistoia V, Airoldi I. IL-27 in human secondary lymphoid organs attracts myeloid dendritic cells and impairs HLA class I-restricted antigen presentation. J Immunol. 2014;192(6):2634-42.
-
(2014)
J Immunol
, vol.192
, Issue.6
, pp. 2634-2642
-
-
Morandi, F.1
Di Carlo, E.2
Ferrone, S.3
Petretto, A.4
Pistoia, V.5
Airoldi, I.6
-
87
-
-
84900519238
-
IL-27 improves migrational and antiviral potential of CB dendritic cells
-
Birkholz J, Doganci A, Darstein C, Gehring S, Zepp F, Meyer CU. IL-27 improves migrational and antiviral potential of CB dendritic cells. Hum Immunol. 2014;75(6):584-91.
-
(2014)
Hum Immunol
, vol.75
, Issue.6
, pp. 584-591
-
-
Birkholz, J.1
Doganci, A.2
Darstein, C.3
Gehring, S.4
Zepp, F.5
Meyer, C.U.6
-
88
-
-
44449140104
-
IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38
-
Kalliolias GD, Ivashkiv LB. IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38. J Immunol. 2008;180(9):6325-33.
-
(2008)
J Immunol
, vol.180
, Issue.9
, pp. 6325-6333
-
-
Kalliolias, G.D.1
Ivashkiv, L.B.2
-
89
-
-
84856021914
-
IL-27 enhances LPS-induced proinfl ammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes
-
Guzzo C, Ayer A, Basta S, Banfi eld BW, Gee K. IL-27 enhances LPS-induced proinfl ammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes. J Immunol. 2012;188(2):864-73.
-
(2012)
J Immunol
, vol.188
, Issue.2
, pp. 864-873
-
-
Guzzo, C.1
Ayer, A.2
Basta, S.3
Banfi Eld, B.W.4
Gee, K.5
-
90
-
-
84897557081
-
IL-27 driven upregulation of surface HLA-E expression on monocytes inhibits IFN-gamma release by autologous NK cells
-
Morandi F, Airoldi I, Pistoia V. IL-27 driven upregulation of surface HLA-E expression on monocytes inhibits IFN-gamma release by autologous NK cells. J Immunol Res. 2014;2014:938561.
-
(2014)
J Immunol Res
, vol.2014
-
-
Morandi, F.1
Airoldi, I.2
Pistoia, V.3
-
91
-
-
78650663329
-
Suppression of TNF-alpha and IL-1 signaling identifi es a mechanism of homeostatic regulation of macrophages by IL-27
-
Kalliolias GD, Gordon RA, Ivashkiv LB. Suppression of TNF-alpha and IL-1 signaling identifi es a mechanism of homeostatic regulation of macrophages by IL-27. J Immunol. 2010;185(11):7047-56.
-
(2010)
J Immunol
, vol.185
, Issue.11
, pp. 7047-7056
-
-
Kalliolias, G.D.1
Gordon, R.A.2
Ivashkiv, L.B.3
-
92
-
-
65549088112
-
Interleukin-27 activates natural killer cells and suppresses NK-resistant head and neck squamous cell carcinoma through inducing antibody-dependent cellular cytotoxicity
-
Matsui M, Kishida T, Nakano H, Yoshimoto K, Shin-Ya M, Shimada T, Nakai S, Imanishi J, Yoshimoto T, Hisa Y, et al. Interleukin-27 activates natural killer cells and suppresses NK-resistant head and neck squamous cell carcinoma through inducing antibody-dependent cellular cytotoxicity. Cancer Res. 2009;69(6):2523-30.
-
(2009)
Cancer Res
, vol.69
, Issue.6
, pp. 2523-2530
-
-
Matsui, M.1
Kishida, T.2
Nakano, H.3
Yoshimoto, K.4
Shin-Ya, M.5
Shimada, T.6
Nakai, S.7
Imanishi, J.8
Yoshimoto, T.9
Hisa, Y.10
-
93
-
-
84879620473
-
Critical role of dendritic cell-derived IL-27 in antitumor immunity through regulating the recruitment and activation of NK and NKT cells
-
Wei J, Xia S, Sun H, Zhang S, Wang J, Zhao H, Wu X, Chen X, Hao J, Zhou X, et al. Critical role of dendritic cell-derived IL-27 in antitumor immunity through regulating the recruitment and activation of NK and NKT cells. J Immunol. 2013;191(1):500-8.
-
(2013)
J Immunol
, vol.191
, Issue.1
, pp. 500-508
-
-
Wei, J.1
Xia, S.2
Sun, H.3
Zhang, S.4
Wang, J.5
Zhao, H.6
Wu, X.7
Chen, X.8
Hao, J.9
Zhou, X.10
-
94
-
-
84921021371
-
IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness
-
Ziblat A, Domaica CI, Spallanzani RG, Iraolagoitia XL, Rossi LE, Avila DE, Torres NI, Fuertes MB, Zwirner NW. IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness. Eur J Immunol. 2015;45(1):192-202.
-
(2015)
Eur J Immunol
, vol.45
, Issue.1
, pp. 192-202
-
-
Ziblat, A.1
Domaica, C.I.2
Spallanzani, R.G.3
Iraolagoitia, X.L.4
Rossi, L.E.5
Avila, D.E.6
Torres, N.I.7
Fuertes, M.B.8
Zwirner, N.W.9
-
95
-
-
80054782482
-
IL-27 imparts immunoregulatory function to human NK cell subsets
-
Laroni A, Gandhi R, Beynon V, Weiner HL. IL-27 imparts immunoregulatory function to human NK cell subsets. PLoS One. 2011;6(10):e26173.
-
(2011)
Plos One
, vol.6
, Issue.10
-
-
Laroni, A.1
Gandhi, R.2
Beynon, V.3
Weiner, H.L.4
-
96
-
-
84872197655
-
Increased synovial expression of IL-27 by IL-17 in rheumatoid arthritis
-
Baek SH, Lee SG, Park YE, Kim GT, Kim CD, Park SY. Increased synovial expression of IL-27 by IL-17 in rheumatoid arthritis. Infl amm Res. 2012;61(12):1339-45.
-
(2012)
Infl Amm Res
, vol.61
, Issue.12
, pp. 1339-1345
-
-
Baek, S.H.1
Lee, S.G.2
Park, Y.E.3
Kim, G.T.4
Kim, C.D.5
Park, S.Y.6
-
97
-
-
79959547499
-
IL-27-producing CD14(+) cells infi ltrate inflamed joints of rheumatoid arthritis and regulate infl ammation and chemotactic migration
-
Tanida S, Yoshitomi H, Ishikawa M, Kasahara T, Murata K, Shibuya H, Ito H, Nakamura T. IL-27-producing CD14(+) cells infi ltrate inflamed joints of rheumatoid arthritis and regulate infl ammation and chemotactic migration. Cytokine. 2011;55(2):237-44.
-
(2011)
Cytokine
, vol.55
, Issue.2
, pp. 237-244
-
-
Tanida, S.1
Yoshitomi, H.2
Ishikawa, M.3
Kasahara, T.4
Murata, K.5
Shibuya, H.6
Ito, H.7
Nakamura, T.8
-
98
-
-
3142719733
-
Suppression of ongoing adjuvantinduced arthritis by neutralizing the function of the p28 subunit of IL-27
-
Goldberg R, Wildbaum G, Zohar Y, Maor G, Karin N. Suppression of ongoing adjuvantinduced arthritis by neutralizing the function of the p28 subunit of IL-27. J Immunol. 2004;173(2):1171-8.
-
(2004)
J Immunol
, vol.173
, Issue.2
, pp. 1171-1178
-
-
Goldberg, R.1
Wildbaum, G.2
Zohar, Y.3
Maor, G.4
Karin, N.5
-
99
-
-
40449100736
-
IL-27 induces a Th1 immune response and susceptibility to experimental arthritis
-
Cao Y, Doodes PD, Glant TT, Finnegan A. IL-27 induces a Th1 immune response and susceptibility to experimental arthritis. J Immunol. 2008;180(2):922-30.
-
(2008)
J Immunol
, vol.180
, Issue.2
, pp. 922-930
-
-
Cao, Y.1
Doodes, P.D.2
Glant, T.T.3
Finnegan, A.4
-
100
-
-
70649113728
-
Common variants at five new loci associated with early-onset inflammatory bowel disease
-
Imielinski M, Baldassano RN, Griffi ths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfi eld JP, Walters TD, Sleiman P, et al. Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet. 2009;41(12):1335-40.
-
(2009)
Nat Genet
, vol.41
, Issue.12
, pp. 1335-1340
-
-
Imielinski, M.1
Baldassano, R.N.2
Griffi Ths, A.3
Russell, R.K.4
Annese, V.5
Dubinsky, M.6
Kugathasan, S.7
Bradfi Eld, J.P.8
Walters, T.D.9
Sleiman, P.10
-
101
-
-
13944281011
-
Expression of interleukin-12-related cytokine transcripts in infl ammatory bowel disease: Elevated interleukin-23p19 and interleukin-27p28 in Crohn’s disease but not in ulcerative colitis
-
Schmidt C, Giese T, Ludwig B, Mueller-Molaian I, Marth T, Zeuzem S, Meuer SC, Stallmach A. Expression of interleukin-12-related cytokine transcripts in infl ammatory bowel disease: elevated interleukin-23p19 and interleukin-27p28 in Crohn’s disease but not in ulcerative colitis. Infl amm Bowel Dis. 2005;11(1):16-23.
-
(2005)
Infl Amm Bowel Dis
, vol.11
, Issue.1
, pp. 16-23
-
-
Schmidt, C.1
Giese, T.2
Ludwig, B.3
Mueller-Molaian, I.4
Marth, T.5
Zeuzem, S.6
Meuer, S.C.7
Stallmach, A.8
-
102
-
-
84855272274
-
A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-infl ammatory proteins
-
Diegelmann J, Olszak T, Goke B, Blumberg RS, Brand S. A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-infl ammatory proteins. J Biol Chem. 2011;287(1):286-98.
-
(2011)
J Biol Chem
, vol.287
, Issue.1
, pp. 286-298
-
-
Diegelmann, J.1
Olszak, T.2
Goke, B.3
Blumberg, R.S.4
Brand, S.5
-
103
-
-
68149163187
-
IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis
-
Troy AE, Zaph C, Du Y, Taylor BC, Guild KJ, Hunter CA, Saris CJ, Artis D. IL-27 regulates homeostasis of the intestinal CD4+ effector T cell pool and limits intestinal inflammation in a murine model of colitis. J Immunol. 2009;183(3):2037-44.
-
(2009)
J Immunol
, vol.183
, Issue.3
, pp. 2037-2044
-
-
Troy, A.E.1
Zaph, C.2
Du, Y.3
Taylor, B.C.4
Guild, K.J.5
Hunter, C.A.6
Saris, C.J.7
Artis, D.8
-
104
-
-
27944495565
-
T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis
-
Honda K, Nakamura K, Matsui N, Takahashi M, Kitamura Y, Mizutani T, Harada N, Nawata H, Hamano S, Yoshida H. T helper 1-inducing property of IL-27/WSX-1 signaling is required for the induction of experimental colitis. Inflamm Bowel Dis. 2005;11(12):1044-52.
-
(2005)
Inflamm Bowel Dis
, vol.11
, Issue.12
, pp. 1044-1052
-
-
Honda, K.1
Nakamura, K.2
Matsui, N.3
Takahashi, M.4
Kitamura, Y.5
Mizutani, T.6
Harada, N.7
Nawata, H.8
Hamano, S.9
Yoshida, H.10
-
105
-
-
44849096815
-
IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD
-
Villarino AV, Artis D, Bezbradica JS, Miller O, Saris CJ, Joyce S, Hunter CA. IL-27R defi - ciency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD. Int Immunol. 2008;20(6):739-52.
-
(2008)
Int Immunol
, vol.20
, Issue.6
, pp. 739-752
-
-
Villarino, A.V.1
Artis, D.2
Bezbradica, J.S.3
Miller, O.4
Saris, C.J.5
Joyce, S.6
Hunter, C.A.7
-
106
-
-
84899495625
-
IL-27, targeting antigen-presenting cells, promotes Th17 differentiation and colitis in mice
-
Visperas A, Do JS, Bulek K, Li X, Min B. IL-27, targeting antigen-presenting cells, promotes Th17 differentiation and colitis in mice. Mucosal Immunol. 2013;7(3):625-33.
-
(2013)
Mucosal Immunol
, vol.7
, Issue.3
, pp. 625-633
-
-
Visperas, A.1
Do, J.S.2
Bulek, K.3
Li, X.4
Min, B.5
-
107
-
-
84873543730
-
A novel role for IL-27 in mediating the survival of activated mouse CD4 T lymphocytes
-
Kim G, Shinnakasu R, Saris CJ, Cheroutre H, Kronenberg M. A novel role for IL-27 in mediating the survival of activated mouse CD4 T lymphocytes. J Immunol. 2013;190(4):1510-8.
-
(2013)
J Immunol
, vol.190
, Issue.4
, pp. 1510-1518
-
-
Kim, G.1
Shinnakasu, R.2
Saris, C.J.3
Cheroutre, H.4
Kronenberg, M.5
-
108
-
-
78651492594
-
IL-27 promotes T cell-dependent colitis through multiple mechanisms
-
Cox JH, Kljavin NM, Ramamoorthi N, Diehl L, Batten M, Ghilardi N. IL-27 promotes T cell-dependent colitis through multiple mechanisms. J Exp Med. 2010;208(1):115-23.
-
(2010)
J Exp Med
, vol.208
, Issue.1
, pp. 115-123
-
-
Cox, J.H.1
Kljavin, N.M.2
Ramamoorthi, N.3
Diehl, L.4
Batten, M.5
Ghilardi, N.6
-
109
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer JS, Laurence A, Wilson EH, Huang E, Tato CM, Johnson LM, Villarino AV, Huang Q, Yoshimura A, Sehy D, et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol. 2006;7(9):937-45.
-
(2006)
Nat Immunol
, vol.7
, Issue.9
, pp. 937-945
-
-
Stumhofer, J.S.1
Laurence, A.2
Wilson, E.H.3
Huang, E.4
Tato, C.M.5
Johnson, L.M.6
Villarino, A.V.7
Huang, Q.8
Yoshimura, A.9
Sehy, D.10
-
110
-
-
47049114262
-
Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t
-
Yang J, Yang M, Htut TM, Ouyang X, Hanidu A, Li X, Sellati R, Jiang H, Zhang S, Li H, et al. Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t. Eur J Immunol. 2008;38(5):1204-14.
-
(2008)
Eur J Immunol
, vol.38
, Issue.5
, pp. 1204-1214
-
-
Yang, J.1
Yang, M.2
Htut, T.M.3
Ouyang, X.4
Hanidu, A.5
Li, X.6
Sellati, R.7
Jiang, H.8
Zhang, S.9
Li, H.10
-
111
-
-
58149400796
-
Early pulmonary cytokine and chemokine responses in mice immunized with three different vaccines against Mycobacterium tuberculosis determined by PCR array
-
Lim J, Derrick SC, Kolibab K, Yang AL, Porcelli S, Jacobs WR, Morris SL. Early pulmonary cytokine and chemokine responses in mice immunized with three different vaccines against Mycobacterium tuberculosis determined by PCR array. Clin Vaccine Immunol: CVI. 2009;16(1):122-6.
-
(2009)
Clin Vaccine Immunol: CVI
, vol.16
, Issue.1
, pp. 122-126
-
-
Lim, J.1
Derrick, S.C.2
Kolibab, K.3
Yang, A.L.4
Porcelli, S.5
Jacobs, W.R.6
Morris, S.L.7
-
112
-
-
34447261677
-
Unique gene expression profiles in infants vaccinated with different strains of Mycobacterium bovis bacille Calmette-Guerin
-
Wu B, Huang C, Garcia L, Ponce De Leon A, Osornio JS, Bobadilla-del-Valle M, Ferreira L, Canizales S, Small P, Kato-Maeda M, et al. Unique gene expression profiles in infants vaccinated with different strains of Mycobacterium bovis bacille Calmette-Guerin. Infect Immun. 2007;75(7):3658-64.
-
(2007)
Infect Immun
, vol.75
, Issue.7
, pp. 3658-3664
-
-
Wu, B.1
Huang, C.2
Garcia, L.3
Ponce De Leon, A.4
Osornio, J.S.5
Bobadilla-Del-Valle, M.6
Ferreira, L.7
Canizales, S.8
Small, P.9
Kato-Maeda, M.10
-
113
-
-
1142311547
-
Expression of IL-27 in human Th1-associated granulomatous diseases
-
Larousserie F, Pfl anz S, Coulomb-L’Hermine A, Brousse N, Kastelein R, Devergne O. Expression of IL-27 in human Th1-associated granulomatous diseases. J Pathol. 2004;202(2):164-71.
-
(2004)
J Pathol
, vol.202
, Issue.2
, pp. 164-171
-
-
Larousserie, F.1
Pfl Anz, S.2
Coulomb-L’hermine, A.3
Brousse, N.4
Kastelein, R.5
Devergne, O.6
-
114
-
-
84957442285
-
Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection
-
Torrado E, Fountain JJ, Liao M, Tighe M, Reiley WW, Lai RP, Meintjes G, Pearl JE, Chen X, Zak DE, et al. Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection. J Exp Med. 2015;212(9):1449-63.
-
(2015)
J Exp Med
, vol.212
, Issue.9
, pp. 1449-1463
-
-
Torrado, E.1
Fountain, J.J.2
Liao, M.3
Tighe, M.4
Reiley, W.W.5
Lai, R.P.6
Meintjes, G.7
Pearl, J.E.8
Chen, X.9
Zak, D.E.10
-
115
-
-
33847419393
-
Noninfectious papilloma virus-like particles inhibit HIV-1 replication: Implications for immune control of HIV-1 infection by IL-27
-
Fakruddin JM, Lempicki RA, Gorelick RJ, Yang J, Adelsberger JW, Garcia-Pineres AJ, Pinto LA, Lane HC, Imamichi T. Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27. Blood. 2007;109(5):1841-9.
-
(2007)
Blood
, vol.109
, Issue.5
, pp. 1841-1849
-
-
Fakruddin, J.M.1
Lempicki, R.A.2
Gorelick, R.J.3
Yang, J.4
Adelsberger, J.W.5
Garcia-Pineres, A.J.6
Pinto, L.A.7
Lane, H.C.8
Imamichi, T.9
-
116
-
-
84888307863
-
Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection
-
Swaminathan S, Dai L, Lane HC, Imamichi T. Evaluating the potential of IL-27 as a novel therapeutic agent in HIV-1 infection. Cytokine Growth Factor Rev. 2013;24(6):571-7.
-
(2013)
Cytokine Growth Factor Rev
, vol.24
, Issue.6
, pp. 571-577
-
-
Swaminathan, S.1
Dai, L.2
Lane, H.C.3
Imamichi, T.4
-
117
-
-
84859485114
-
Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling
-
Liu L, Cao Z, Chen J, Li R, Cao Y, Zhu C, Wu K, Wu J, Liu F, Zhu Y. Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling. J Biol Chem. 2012;287(15):11899-910.
-
(2012)
J Biol Chem
, vol.287
, Issue.15
, pp. 11899-11910
-
-
Liu, L.1
Cao, Z.2
Chen, J.3
Li, R.4
Cao, Y.5
Zhu, C.6
Wu, K.7
Wu, J.8
Liu, F.9
Zhu, Y.10
-
118
-
-
84873104887
-
Maintenance of CMV-specific CD8+ T cell responses and the relationship of IL-27 to IFN-gamma levels with aging
-
Shin MS, Lee JS, Lee N, Lee WW, Kim SH, Kang I. Maintenance of CMV-specific CD8+ T cell responses and the relationship of IL-27 to IFN-gamma levels with aging. Cytokine. 2013;61(2):485-90.
-
(2013)
Cytokine
, vol.61
, Issue.2
, pp. 485-490
-
-
Shin, M.S.1
Lee, J.S.2
Lee, N.3
Lee, W.W.4
Kim, S.H.5
Kang, I.6
-
119
-
-
63249115116
-
Hepatitis B virus enhances interleukin-27 expression both in vivo and in vitro
-
Zhu C, Zhang R, Liu L, Rasool ST, Mu Y, Sun W, Hao Q, Liu F, Zhu Y, Wu J. Hepatitis B virus enhances interleukin-27 expression both in vivo and in vitro. Clin Immunol. 2009;131(1):92-7.
-
(2009)
Clin Immunol
, vol.131
, Issue.1
, pp. 92-97
-
-
Zhu, C.1
Zhang, R.2
Liu, L.3
Rasool, S.T.4
Mu, Y.5
Sun, W.6
Hao, Q.7
Liu, F.8
Zhu, Y.9
Wu, J.10
-
120
-
-
84863708860
-
The correlation between hepatitis B virus infection and IL-27
-
Wang HL, Zhang HY, Zhai ZL, Zhou X. The correlation between hepatitis B virus infection and IL-27. Biomed Mater Eng. 2012;22(1-3):187-93.
-
(2012)
Biomed Mater Eng
, vol.22
, Issue.1-3
, pp. 187-193
-
-
Wang, H.L.1
Zhang, H.Y.2
Zhai, Z.L.3
Zhou, X.4
-
121
-
-
84877080684
-
Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties
-
Swaminathan S, Hu X, Zheng X, Kriga Y, Shetty J, Zhao Y, Stephens R, Tran B, Baseler MW, Yang J, et al. Interleukin-27 treated human macrophages induce the expression of novel microRNAs which may mediate anti-viral properties. Biochem Biophys Res Commun. 2013;434(2):228-34.
-
(2013)
Biochem Biophys Res Commun
, vol.434
, Issue.2
, pp. 228-234
-
-
Swaminathan, S.1
Hu, X.2
Zheng, X.3
Kriga, Y.4
Shetty, J.5
Zhao, Y.6
Stephens, R.7
Tran, B.8
Baseler, M.W.9
Yang, J.10
-
122
-
-
64249118418
-
Immunologic and therapeutic synergy of IL-27 and IL-2: Enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow
-
Salcedo R, Hixon JA, Stauffer JK, Jalah R, Brooks AD, Khan T, Dai RM, Scheetz L, Lincoln E, Back TC, et al. Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow. J Immunol. 2009;182(7):4328-38.
-
(2009)
J Immunol
, vol.182
, Issue.7
, pp. 4328-4338
-
-
Salcedo, R.1
Hixon, J.A.2
Stauffer, J.K.3
Jalah, R.4
Brooks, A.D.5
Khan, T.6
Dai, R.M.7
Scheetz, L.8
Lincoln, E.9
Back, T.C.10
-
123
-
-
77951923924
-
IL-12 and IL-27 sequential gene therapy via intramuscular electroporation delivery for eliminating distal aggressive tumors
-
Zhu S, Lee DA, Li S. IL-12 and IL-27 sequential gene therapy via intramuscular electroporation delivery for eliminating distal aggressive tumors. J Immunol. 2010;184(5):2348-54.
-
(2010)
J Immunol
, vol.184
, Issue.5
, pp. 2348-2354
-
-
Zhu, S.1
Lee, D.A.2
Li, S.3
-
124
-
-
84868521662
-
Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response
-
Perona-Wright G, Kohlmeier JE, Bassity E, Freitas TC, Mohrs K, Cookenham T, Situ H, Pearce EJ, Woodland DL, Mohrs M. Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response. Proc Natl Acad Sci U S A. 2012;109(45):18535-40.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.45
, pp. 18535-18540
-
-
Perona-Wright, G.1
Kohlmeier, J.E.2
Bassity, E.3
Freitas, T.C.4
Mohrs, K.5
Cookenham, T.6
Situ, H.7
Pearce, E.J.8
Woodland, D.L.9
Mohrs, M.10
-
125
-
-
84873745745
-
IL-27 enhances the survival of tumor antigen- specific CD8+ T cells and programs them into IL-10-producing, memory precursorlike effector cells
-
Liu Z, Liu JQ, Talebian F, Wu LC, Li S, Bai XF. IL-27 enhances the survival of tumor antigen- specific CD8+ T cells and programs them into IL-10-producing, memory precursorlike effector cells. Eur J Immunol. 2012;43(2):468-79.
-
(2012)
Eur J Immunol
, vol.43
, Issue.2
, pp. 468-479
-
-
Liu, Z.1
Liu, J.Q.2
Talebian, F.3
Wu, L.C.4
Li, S.5
Bai, X.F.6
-
126
-
-
79955777815
-
WSX1 expression in tumors induces immune tolerance via suppression of effector immune cells
-
Dibra D, Cutrera J, Xia X, Li S. WSX1 expression in tumors induces immune tolerance via suppression of effector immune cells. PLoS One. 2011;6(4):e19072.
-
(2011)
Plos One
, vol.6
, Issue.4
-
-
Dibra, D.1
Cutrera, J.2
Xia, X.3
Li, S.4
-
127
-
-
45549106117
-
Antiproliferative activity of IL-27 on melanoma
-
Yoshimoto T, Morishima N, Mizoguchi I, Shimizu M, Nagai H, Oniki S, Oka M, Nishigori C, Mizuguchi J. Antiproliferative activity of IL-27 on melanoma. J Immunol. 2008;180(10):6527-35.
-
(2008)
J Immunol
, vol.180
, Issue.10
, pp. 6527-6535
-
-
Yoshimoto, T.1
Morishima, N.2
Mizoguchi, I.3
Shimizu, M.4
Nagai, H.5
Oniki, S.6
Oka, M.7
Nishigori, C.8
Mizuguchi, J.9
-
128
-
-
33744909098
-
Antiangiogenic and antitumor activities of IL-27
-
Shimizu M, Shimamura M, Owaki T, Asakawa M, Fujita K, Kudo M, Iwakura Y, Takeda Y, Luster AD, Mizuguchi J, et al. Antiangiogenic and antitumor activities of IL-27. J Immunol. 2006;176(12):7317-24.
-
(2006)
J Immunol
, vol.176
, Issue.12
, pp. 7317-7324
-
-
Shimizu, M.1
Shimamura, M.2
Owaki, T.3
Asakawa, M.4
Fujita, K.5
Kudo, M.6
Iwakura, Y.7
Takeda, Y.8
Luster, A.D.9
Mizuguchi, J.10
-
129
-
-
83555165176
-
Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model
-
Canale S, Cocco C, Frasson C, Seganfreddo E, Di Carlo E, Ognio E, Sorrentino C, Ribatti D, Zorzoli A, Basso G, et al. Interleukin-27 inhibits pediatric B-acute lymphoblastic leukemia cell spreading in a preclinical model. Leukemia. 2011;25(12):1815-24.
-
(2011)
Leukemia
, vol.25
, Issue.12
, pp. 1815-1824
-
-
Canale, S.1
Cocco, C.2
Frasson, C.3
Seganfreddo, E.4
Di Carlo, E.5
Ognio, E.6
Sorrentino, C.7
Ribatti, D.8
Zorzoli, A.9
Basso, G.10
-
130
-
-
84858233334
-
Interleukin-27 inhibits the growth of pediatric acute myeloid leukemia in NOD/SCID/Il2rg-/- mice
-
Zorzoli A, Di Carlo E, Cocco C, Ognio E, Ribatti D, Ferretti E, Dufour C, Locatelli F, Montagna D, Airoldi I. Interleukin-27 inhibits the growth of pediatric acute myeloid leukemia in NOD/SCID/Il2rg-/- mice. Clin Cancer Res. 2012;18(6):1630-40.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.6
, pp. 1630-1640
-
-
Zorzoli, A.1
Di Carlo, E.2
Cocco, C.3
Ognio, E.4
Ribatti, D.5
Ferretti, E.6
Dufour, C.7
Locatelli, F.8
Montagna, D.9
Airoldi, I.10
-
131
-
-
77955720345
-
Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma
-
Cocco C, Giuliani N, Di Carlo E, Ognio E, Storti P, Abeltino M, Sorrentino C, Ponzoni M, Ribatti D, Airoldi I. Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma. Clin Cancer Res. 2010;16(16):4188-97.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.16
, pp. 4188-4197
-
-
Cocco, C.1
Giuliani, N.2
Di Carlo, E.3
Ognio, E.4
Storti, P.5
Abeltino, M.6
Sorrentino, C.7
Ponzoni, M.8
Ribatti, D.9
Airoldi, I.10
-
132
-
-
84864914763
-
Anti-leukemic properties of IL-12, IL-23 and IL-27: Differences and similarities in the control of pediatric B acute lymphoblastic leukemia
-
Cocco C, Pistoia V, Airoldi I. Anti-leukemic properties of IL-12, IL-23 and IL-27: differences and similarities in the control of pediatric B acute lymphoblastic leukemia. Crit Rev Oncol Hematol. 2012;83(3):310-8.
-
(2012)
Crit Rev Oncol Hematol
, vol.83
, Issue.3
, pp. 310-318
-
-
Cocco, C.1
Pistoia, V.2
Airoldi, I.3
-
133
-
-
84923088133
-
An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction
-
Zhu C, Sakuishi K, Xiao S, Sun Z, Zaghouani S, Gu G, Wang C, Tan DJ, Wu C, Rangachari M, et al. An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. Nat Commun. 2015;6:6072.
-
(2015)
Nat Commun
, vol.6
, pp. 6072
-
-
Zhu, C.1
Sakuishi, K.2
Xiao, S.3
Sun, Z.4
Zaghouani, S.5
Gu, G.6
Wang, C.7
Tan, D.J.8
Wu, C.9
Rangachari, M.10
-
134
-
-
84929254530
-
Resident bacteria-stimulated IL-10-secreting B cells ameliorate T cell-mediated colitis by inducing Tr-1 cells that require IL-27-signaling
-
Mishima Y, Liu B, Hansen JJ, Sartor RB. Resident bacteria-stimulated IL-10-secreting B cells ameliorate T cell-mediated colitis by inducing Tr-1 cells that require IL-27-signaling. Cell Mol Gastroenterol Hepatol. 2015;1(3):295-310.
-
(2015)
Cell Mol Gastroenterol Hepatol
, vol.1
, Issue.3
, pp. 295-310
-
-
Mishima, Y.1
Liu, B.2
Hansen, J.J.3
Sartor, R.B.4
-
135
-
-
79955000536
-
IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis
-
Ansari NA, Kumar R, Gautam S, Nylen S, Singh OP, Sundar S, Sacks D. IL-27 and IL-21 are associated with T cell IL-10 responses in human visceral leishmaniasis. J Immunol. 2011;186(7):3977-85.
-
(2011)
J Immunol
, vol.186
, Issue.7
, pp. 3977-3985
-
-
Ansari, N.A.1
Kumar, R.2
Gautam, S.3
Nylen, S.4
Singh, O.P.5
Sundar, S.6
Sacks, D.7
-
136
-
-
84939266609
-
The paradoxical role of IL-10 in immunity and cancer
-
Mannino MH, Zhu Z, Xiao H, Bai Q, Wakefi eld MR, Fang Y. The paradoxical role of IL-10 in immunity and cancer. Cancer Lett. 2015;367(2):103-7.
-
(2015)
Cancer Lett
, vol.367
, Issue.2
, pp. 103-107
-
-
Mannino, M.H.1
Zhu, Z.2
Xiao, H.3
Bai, Q.4
Wakefi Eld, M.R.5
Fang, Y.6
-
137
-
-
84929342210
-
Antagonists of PD-1 and PD-L1 in cancer treatment
-
Lipson EJ, Forde PM, Hammers HJ, Emens LA, Taube JM, Topalian SL. Antagonists of PD-1 and PD-L1 in cancer treatment. Semin Oncol. 2015;42(4):587-600.
-
(2015)
Semin Oncol
, vol.42
, Issue.4
, pp. 587-600
-
-
Lipson, E.J.1
Forde, P.M.2
Hammers, H.J.3
Emens, L.A.4
Taube, J.M.5
Topalian, S.L.6
-
138
-
-
20844456664
-
GM-CSF gene-transduced tumor vaccines
-
Eager R, Nemunaitis J. GM-CSF gene-transduced tumor vaccines. Mol Ther. 2005;12(1):18-27.
-
(2005)
Mol Ther
, vol.12
, Issue.1
, pp. 18-27
-
-
Eager, R.1
Nemunaitis, J.2
|