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Volumn 188, Issue 2, 2012, Pages 864-873

IL-27 enhances LPS-induced proinflammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 27; INTERLEUKIN 6; JANUS KINASE 2; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84856021914     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101912     Document Type: Article
Times cited : (84)

References (51)
  • 3
    • 77955302693 scopus 로고    scopus 로고
    • Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes
    • Guzzo, C., N. F. Che Mat, and K. Gee. 2010. Interleukin-27 induces a STAT1/3- and NF-kappaB-dependent proinflammatory cytokine profile in human monocytes. J. Biol. Chem. 285: 24404-24411.
    • (2010) J. Biol. Chem. , vol.285 , pp. 24404-24411
    • Guzzo, C.1    Che Mat, N.F.2    Gee, K.3
  • 5
    • 44449140104 scopus 로고    scopus 로고
    • IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38
    • Kalliolias, G. D., and L. B. Ivashkiv. 2008. IL-27 activates human monocytes via STAT1 and suppresses IL-10 production but the inflammatory functions of IL-27 are abrogated by TLRs and p38. J. Immunol. 180: 6325-6333.
    • (2008) J. Immunol. , vol.180 , pp. 6325-6333
    • Kalliolias, G.D.1    Ivashkiv, L.B.2
  • 6
    • 13544251389 scopus 로고    scopus 로고
    • Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: A novel role for the cAMP pathway
    • DOI 10.1182/blood-2004-05-1718
    • Schnurr, M., T. Toy, A. Shin, M. Wagner, J. Cebon, and E. Maraskovsky. 2005. Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway. Blood 105: 1582-1589. (Pubitemid 40223678)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1582-1589
    • Schnurr, M.1    Toy, T.2    Shin, A.3    Wagner, M.4    Cebon, J.5    Maraskovsky, E.6
  • 7
    • 0035911644 scopus 로고    scopus 로고
    • Identification of hTLR10: A novel human Toll-like receptor preferentially expressed in immune cells
    • DOI 10.1016/S0167-4781(00)00289-X, PII S016747810000289X
    • Chuang, T., and R. J. Ulevitch. 2001. Identification of hTLR10: a novel human Toll-like receptor preferentially expressed in immune cells. Biochim. Biophys. Acta 1518: 157-161. (Pubitemid 32232289)
    • (2001) Biochimica et Biophysica Acta - Gene Structure and Expression , vol.1518 , Issue.1-2 , pp. 157-161
    • Chuang, T.-H.1    Ulevitch, R.J.2
  • 8
    • 0034457684 scopus 로고    scopus 로고
    • Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9
    • Chuang, T. H., and R. J. Ulevitch. 2000. Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur. Cytokine Netw. 11: 372-378.
    • (2000) Eur. Cytokine Netw. , vol.11 , pp. 372-378
    • Chuang, T.H.1    Ulevitch, R.J.2
  • 9
    • 0034456693 scopus 로고    scopus 로고
    • Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
    • Du, X., A. Poltorak, Y. Wei, and B. Beutler. 2000. Three novel mammalian toll-like receptors: gene structure, expression, and evolution. Eur. Cytokine Netw. 11: 362-371. (Pubitemid 32268893)
    • (2000) European Cytokine Network , vol.11 , Issue.3 , pp. 362-371
    • Du, X.1    Poltorak, A.2    Wei, Y.3    Beutler, B.4
  • 11
    • 0033614428 scopus 로고    scopus 로고
    • TLR6: A novel member of an expanding Toll-like receptor family
    • DOI 10.1016/S0378-1119(99)00098-0, PII S0378111999000980
    • Takeuchi, O., T. Kawai, H. Sanjo, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, K. Takeda, and S. Akira. 1999. TLR6: A novel member of an expanding toll-like receptor family. Gene 231: 59-65. (Pubitemid 29307773)
    • (1999) Gene , vol.231 , Issue.1-2 , pp. 59-65
    • Takeuchi, O.1    Kawai, T.2    Sanjo, H.3    Copeland, N.G.4    Gilbert, D.J.5    Jenkins, N.A.6    Takeda, K.7    Akira, S.8
  • 12
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember, K. A., and P. J. Godowski. 2002. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J. Immunol. 168: 554-561. (Pubitemid 34049553)
    • (2002) Journal of Immunology , vol.168 , Issue.2 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 13
    • 0033574415 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
    • Chow, J. C., D. W. Young, D. T. Golenbock, W. J. Christ, and F. Gusovsky. 1999. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 274: 10689-10692.
    • (1999) J. Biol. Chem. , vol.274 , pp. 10689-10692
    • Chow, J.C.1    Young, D.W.2    Golenbock, D.T.3    Christ, W.J.4    Gusovsky, F.5
  • 14
    • 0035104119 scopus 로고    scopus 로고
    • LPS induction of gene expression in human monocytes
    • DOI 10.1016/S0898-6568(00)00149-2, PII S0898656800001492
    • Guha, M., and N. Mackman. 2001. LPS induction of gene expression in human monocytes. Cell. Signal. 13: 85-94. (Pubitemid 32222977)
    • (2001) Cellular Signalling , vol.13 , Issue.2 , pp. 85-94
    • Guha, M.1    Mackman, N.2
  • 15
    • 35348856289 scopus 로고    scopus 로고
    • Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells
    • DOI 10.1007/s12026-007-0069-0
    • Gioannini, T. L., and J. P.Weiss. 2007. Regulation of interactions of Gram-negative bacterial endotoxins with mammalian cells. Immunol. Res. 39: 249-260. (Pubitemid 47574891)
    • (2007) Immunologic Research , vol.39 , Issue.1-3 , pp. 249-260
    • Gioannini, T.L.1    Weiss, J.P.2
  • 16
    • 35048817885 scopus 로고    scopus 로고
    • Kinetics of binding of LPS to recombinant CD14, TLR4, and MD-2 proteins
    • Shin, H. J., H. Lee, J. D. Park, H. C. Hyun, H. O. Sohn, D. W. Lee, and Y. S. Kim. 2007. Kinetics of binding of LPS to recombinant CD14, TLR4, and MD-2 proteins. Mol. Cells 24: 119-124. (Pubitemid 47554799)
    • (2007) Molecules and Cells , vol.24 , Issue.1 , pp. 119-124
    • Shin, H.J.1    Lee, H.2    Park, J.D.3    Hyun, H.C.4    Sohn, H.O.5    Lee, D.W.6    Kim, Y.S.7
  • 17
    • 0035958007 scopus 로고    scopus 로고
    • The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages
    • Ma, W., W. Lim, K. Gee, S. Aucoin, D. Nandan, M. Kozlowski, F. Diaz-Mitoma, and A. Kumar. 2001. The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. J. Biol. Chem. 276: 13664-13674.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13664-13674
    • Ma, W.1    Lim, W.2    Gee, K.3    Aucoin, S.4    Nandan, D.5    Kozlowski, M.6    Diaz-Mitoma, F.7    Kumar, A.8
  • 18
    • 67749093316 scopus 로고    scopus 로고
    • TNF-alpha inhibits toll-like receptor 4 expression on monocytic cells via tristetraprolin during cardiopulmonary bypass
    • Tsai, C. S., D. L. Chen, S. J. Lin, J. C. Tsai, T. C. Lin, C. Y. Lin, Y. H. Chen, G. S. Huang, H. Y. Tsai, F. Y. Lin, and C. Y. Li. 2009. TNF-alpha inhibits toll-like receptor 4 expression on monocytic cells via tristetraprolin during cardiopulmonary bypass. Shock 32: 40-48.
    • (2009) Shock , vol.32 , pp. 40-48
    • Tsai, C.S.1    Chen, D.L.2    Lin, S.J.3    Tsai, J.C.4    Lin, T.C.5    Lin, C.Y.6    Chen, Y.H.7    Huang, G.S.8    Tsai, H.Y.9    Lin, F.Y.10    Li, C.Y.11
  • 19
    • 2342583421 scopus 로고    scopus 로고
    • Modulation of toll-like receptor 4 expression on human monocytes by tumor necrosis factor and interleukin-6: Tumor necrosis factor evokes lipopolysaccharide hyporesponsiveness, whereas interleukin-6 enhances lipopolysaccharide activity
    • Tamandl, D., M. Bahrami, B. Wessner, G. Weigel, M. Ploder, W. Fürst, E. Roth, G. Boltz-Nitulescu, and A. Spittler. 2003. Modulation of toll-like receptor 4 expression on human monocytes by tumor necrosis factor and interleukin-6: tumor necrosis factor evokes lipopolysaccharide hyporesponsiveness, whereas interleukin-6 enhances lipopolysaccharide activity. Shock 20: 224-229.
    • (2003) Shock , vol.20 , pp. 224-229
    • Tamandl, D.1    Bahrami, M.2    Wessner, B.3    Weigel, G.4    Ploder, M.5    Fürst, W.6    Roth, E.7    Boltz-Nitulescu, G.8    Spittler, A.9
  • 20
    • 0036565888 scopus 로고    scopus 로고
    • Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: A molecular basis for priming and synergism with bacterial lipopolysaccharide
    • DOI 10.1182/blood.V99.9.3427
    • Bosisio, D., N. Polentarutti, M. Sironi, S. Bernasconi, K. Miyake, G. R. Webb, M. U. Martin, A. Mantovani, and M. Muzio. 2002. Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-gamma: a molecular basis for priming and synergism with bacterial lipopolysaccharide. Blood 99: 3427-3431. (Pubitemid 34525326)
    • (2002) Blood , vol.99 , Issue.9 , pp. 3427-3431
    • Bosisio, D.1    Polentarutti, N.2    Sironi, M.3    Bernasconi, S.4    Miyake, K.5    Webb, G.R.6    Martin, M.U.7    Mantovani, A.8    Muzio, M.9
  • 21
    • 0036533202 scopus 로고    scopus 로고
    • Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4
    • DOI 10.1016/S0165-2478(01)00328-5, PII S0165247801003285
    • Mita, Y., K. Dobashi, K. Endou, T. Kawata, Y. Shimizu, T. Nakazawa, and M. Mori. 2002. Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4. Immunol. Lett. 81: 71-75. (Pubitemid 34159043)
    • (2002) Immunology Letters , vol.81 , Issue.1 , pp. 71-75
    • Mita, Y.1    Dobashi, K.2    Endou, K.3    Kawata, T.4    Shimizu, Y.5    Nakazawa, T.6    Mori, M.7
  • 22
    • 33845310503 scopus 로고    scopus 로고
    • SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation
    • DOI 10.1158/1078-0432.CCR-06-1330
    • Duan, Z., J. E. Bradner, E. Greenberg, R. Levine, R. Foster, J. Mahoney, and M. V. Seiden. 2006. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation. Clin. Cancer Res. 12: 6844-6852. (Pubitemid 44876855)
    • (2006) Clinical Cancer Research , vol.12 , Issue.22 , pp. 6844-6852
    • Duan, Z.1    Bradner, J.E.2    Greenberg, E.3    Levine, R.4    Foster, R.5    Mahoney, J.6    Seiden, M.V.7
  • 24
    • 47049124548 scopus 로고    scopus 로고
    • IL-12, IL-23, and IL-27 enhance human beta-defensin- 2 production in human keratinocytes
    • Kanda, N., and S. Watanabe. 2008. IL-12, IL-23, and IL-27 enhance human beta-defensin- 2 production in human keratinocytes. Eur. J. Immunol. 38: 1287-1296.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1287-1296
    • Kanda, N.1    Watanabe, S.2
  • 25
    • 36749024030 scopus 로고    scopus 로고
    • Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor
    • DOI 10.1073/pnas.0702388104
    • Pradhan, A., Q. T. Lambert, and G. W. Reuther. 2007. Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor. Proc. Natl. Acad. Sci. USA 104: 18502-18507. (Pubitemid 350210726)
    • (2007) Proceedings of the National Academy of Sciences of the United States of America , vol.104 , Issue.47 , pp. 18502-18507
    • Pradhan, A.1    Lambert, Q.T.2    Reuther, G.W.3
  • 26
    • 0035831040 scopus 로고    scopus 로고
    • Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription
    • Mowen, K. A., J. Tang, W. Zhu, B. T. Schurter, K. Shuai, H. R. Herschman, and M. David. 2001. Arginine methylation of STAT1 modulates IFNalpha/beta-induced transcription. Cell 104: 731-741. (Pubitemid 32241023)
    • (2001) Cell , vol.104 , Issue.5 , pp. 731-741
    • Mowen, K.A.1    Tang, J.2    Zhu, W.3    Schurter, B.T.4    Shuai, K.5    Herschman, H.R.6    David, M.7
  • 27
    • 2142825067 scopus 로고    scopus 로고
    • Progressive dysregulation of transcription factors NF-kappa B and STAT1 in prostate cancer cells causes proangiogenic production of CXC chemokines
    • Shen, H., and A. B. Lentsch. 2004. Progressive dysregulation of transcription factors NF-kappa B and STAT1 in prostate cancer cells causes proangiogenic production of CXC chemokines. Am. J. Physiol. Cell Physiol. 286: C840-C847. (Pubitemid 38543813)
    • (2004) American Journal of Physiology - Cell Physiology , vol.286 , Issue.4
    • Shen, H.1    Lentsch, A.B.2
  • 28
    • 79953246187 scopus 로고    scopus 로고
    • Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus kinase/signal transducer and activation of transcription pathway in human CD4 T cells
    • Che Mat, N. F., X. Zhang, C. Guzzo, and K. Gee. 2011. Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus kinase/signal transducer and activation of transcription pathway in human CD4 T cells. J. Interferon Cytokine Res. 31: 363-371.
    • (2011) J. Interferon Cytokine Res. , vol.31 , pp. 363-371
    • Che Mat, N.F.1    Zhang, X.2    Guzzo, C.3    Gee, K.4
  • 29
    • 47749107900 scopus 로고    scopus 로고
    • Inhibition of the signal transducer and activator of transcription-3 (STAT3) signaling pathway by 4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxylic acid esters
    • DOI 10.1021/jm701271y
    • Xu, J., D. C. Cole, C. P. Chang, R. Ayyad, M. Asselin, W. Hao, J. Gibbons, S. A. Jelinsky, K. A. Saraf, and K. Park. 2008. Inhibition of the signal transducer and activator of transcription-3 (STAT3) signaling pathway by 4-oxo-1-phenyl- 1,4-dihydroquinoline-3-carboxylic acid esters. J. Med. Chem. 51: 4115-4121. (Pubitemid 352032439)
    • (2008) Journal of Medicinal Chemistry , vol.51 , Issue.14 , pp. 4115-4121
    • Xu, J.1    Cole, D.C.2    Chang, C.-P.B.3    Ayyad, R.4    Asselin, M.5    Hao, W.6    Gibbons, J.7    Jelinsky, S.A.8    Saraf, K.A.9    Park, K.10
  • 30
    • 78149455161 scopus 로고    scopus 로고
    • Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: Implication for the pathogenesis of necrotizing enterocolitis
    • Soliman, A., K. S. Michelsen, H. Karahashi, J. Lu, F. J. Meng, X. Qu, T. R. Crother, S. Rabizadeh, S. Chen, M. S. Caplan, et al. 2010. Platelet-activating factor induces TLR4 expression in intestinal epithelial cells: implication for the pathogenesis of necrotizing enterocolitis. PLoS ONE 5: e15044.
    • (2010) PLoS ONE , vol.5
    • Soliman, A.1    Michelsen, K.S.2    Karahashi, H.3    Lu, J.4    Meng, F.J.5    Qu, X.6    Crother, T.R.7    Rabizadeh, S.8    Chen, S.9    Caplan, M.S.10
  • 31
    • 77949983956 scopus 로고    scopus 로고
    • Cyclic stretch enhances the expression of toll-like receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-kappaB pathway
    • Shyu, K. G., B. W. Wang, C. M. Lin, and H. Chang. 2010. Cyclic stretch enhances the expression of toll-like receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-kappaB pathway. J. Biomed. Sci. 17: 15.
    • (2010) J. Biomed. Sci. , vol.17 , pp. 15
    • Shyu, K.G.1    Wang, B.W.2    Lin, C.M.3    Chang, H.4
  • 33
    • 0035833541 scopus 로고    scopus 로고
    • Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades
    • DOI 10.1038/35088074
    • Digicaylioglu, M., and S. A. Lipton. 2001. Erythropoietin-mediated neuro-protection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature 412: 641-647. (Pubitemid 32772276)
    • (2001) Nature , vol.412 , Issue.6847 , pp. 641-647
    • Digicaylioglu, M.1    Lipton, S.A.2
  • 34
    • 77549083560 scopus 로고    scopus 로고
    • Dangerous liaisons: STAT3 and NFkappaB collaboration and crosstalk in cancer
    • Grivennikov, S. I., and M. Karin. 2010. Dangerous liaisons: STAT3 and NFkappaB collaboration and crosstalk in cancer. Cytokine Growth Factor Rev. 21: 11-19.
    • (2010) Cytokine Growth Factor Rev. , vol.21 , pp. 11-19
    • Grivennikov, S.I.1    Karin, M.2
  • 36
    • 33847708375 scopus 로고    scopus 로고
    • Specific high affinity interactions of monomeric endotoxin protein complexes with toll-like receptor 4 ectodomain
    • DOI 10.1074/jbc.M609400200
    • Prohinar, P., F. Re, R. Widstrom, D. Zhang, A. Teghanemt, J. P. Weiss, and T. L. Gioannini. 2007. Specific high affinity interactions of monomeric endotoxin. protein complexes with Toll-like receptor 4 ectodomain. J. Biol. Chem. 282: 1010-1017. (Pubitemid 47076551)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.2 , pp. 1010-1017
    • Prohinar, P.1    Re, F.2    Widstrom, R.3    Zhang, D.4    Teghanemt, A.5    Weiss, J.P.6    Gioannini, T.L.7
  • 38
    • 0031684844 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-kappaB p50
    • Baer, M., A. Dillner, R. C. Schwartz, C. Sedon, S. Nedospasov, and P. F. Johnson. 1998. Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-kappaB p50. Mol. Cell. Biol. 18: 5678-5689. (Pubitemid 28450519)
    • (1998) Molecular and Cellular Biology , vol.18 , Issue.10 , pp. 5678-5689
    • Baer, M.1    Dillner, A.2    Schwartz, R.C.3    Sedon, C.4    Nedospasov, S.5    Johnson, P.F.6
  • 39
    • 34547815755 scopus 로고    scopus 로고
    • Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade
    • DOI 10.1126/science.1142953
    • Carmody, R. J., Q. Ruan, S. Palmer, B. Hilliard, and Y. H. Chen. 2007. Negative regulation of toll-like receptor signaling by NF-kappaB p50 ubiquitination blockade. Science 317: 675-678. (Pubitemid 47229968)
    • (2007) Science , vol.317 , Issue.5838 , pp. 675-678
    • Carmody, R.J.1    Ruan, Q.2    Palmer, S.3    Hilliard, B.4    Chen, Y.H.5
  • 40
    • 0347949510 scopus 로고    scopus 로고
    • Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: A role for p50
    • DOI 10.1111/j.1365-2249.2004.02342.x
    • Driessler, F., K. Venstrom, R. Sabat, K. Asadullah, and A. J. Schottelius. 2004. Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50. Clin. Exp. Immunol. 135: 64-73. (Pubitemid 38067929)
    • (2004) Clinical and Experimental Immunology , vol.135 , Issue.1 , pp. 64-73
    • Driessler, F.1    Venstrom, K.2    Sabat, R.3    Asadullah, K.4    Schottelius, A.J.5
  • 41
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • DOI 10.1038/nrm2083, PII NRM2083
    • Perkins, N. D. 2007. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat. Rev. Mol. Cell Biol. 8: 49-62. (Pubitemid 46012014)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.1 , pp. 49-62
    • Perkins, N.D.1
  • 42
    • 55149093640 scopus 로고    scopus 로고
    • Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms
    • Hu, X., S. D. Chakravarty, and L. B. Ivashkiv. 2008. Regulation of interferon and Toll-like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms. Immunol. Rev. 226: 41-56.
    • (2008) Immunol. Rev. , vol.226 , pp. 41-56
    • Hu, X.1    Chakravarty, S.D.2    Ivashkiv, L.B.3
  • 43
    • 78650647259 scopus 로고    scopus 로고
    • Lipopolysaccharide-mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages
    • Iyer, S. S., A. A. Ghaffari, and G. Cheng. 2010. Lipopolysaccharide- mediated IL-10 transcriptional regulation requires sequential induction of type I IFNs and IL-27 in macrophages. J. Immunol. 185: 6599-6607.
    • (2010) J. Immunol. , vol.185 , pp. 6599-6607
    • Iyer, S.S.1    Ghaffari, A.A.2    Cheng, G.3
  • 44
    • 33846440515 scopus 로고    scopus 로고
    • Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways
    • DOI 10.1084/jem.20061440
    • Liu, J., X. Guan, and X. Ma. 2007. Regulation of IL-27 p28 gene expression in macrophages through MyD88- and interferon-gamma-mediated pathways. J. Exp. Med. 204: 141-152. (Pubitemid 46148764)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.1 , pp. 141-152
    • Liu, J.1    Guan, X.2    Ma, X.3
  • 45
    • 36249017932 scopus 로고    scopus 로고
    • IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages
    • DOI 10.1189/jlb.0307157
    • Pirhonen, J., J. Sirén, I. Julkunen, and S. Matikainen. 2007. IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages. J. Leukoc. Biol. 82: 1185-1192. (Pubitemid 350133516)
    • (2007) Journal of Leukocyte Biology , vol.82 , Issue.5 , pp. 1185-1192
    • Pirhonen, J.1    Siren, J.2    Julkunen, I.3    Matikainen, S.4
  • 46
  • 47
    • 12344288451 scopus 로고    scopus 로고
    • Biology of recently discovered cytokines: Discerning the pro- and anti-inflammatory properties of interleukin-27
    • DOI 10.1186/ar1227
    • Villarino, A. V., and C. A. Hunter. 2004. Biology of recently discovered cytokines: discerning the pro- and anti-inflammatory properties of interleukin-27. Arthritis Res. Ther. 6: 225-233. (Pubitemid 40124374)
    • (2004) Arthritis Research and Therapy , vol.6 , Issue.5 , pp. 225-233
    • Villarino, A.V.1    Hunter, C.A.2
  • 49
    • 14844355133 scopus 로고    scopus 로고
    • The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis
    • Hölscher, C., A. Hölscher, D. Rückerl, T. Yoshimoto, H. Yoshida, T. Mak, C. Saris, and S. Ehlers. 2005. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J. Immunol. 174: 3534-3544. (Pubitemid 40354062)
    • (2005) Journal of Immunology , vol.174 , Issue.6 , pp. 3534-3544
    • Holscher, C.1    Holscher, A.2    Ruckerl, D.3    Yoshimoto, T.4    Yoshida, H.5    Mak, T.6    Saris, C.7    Ehlers, S.8
  • 50
    • 33747344010 scopus 로고    scopus 로고
    • Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1
    • Rückerl, D., M. Hessmann, T. Yoshimoto, S. Ehlers, and C. Hölscher. 2006. Alternatively activated macrophages express the IL-27 receptor alpha chain WSX-1. Immunobiology 211: 427-436.
    • (2006) Immunobiology , vol.211 , pp. 427-436
    • Rückerl, D.1    Hessmann, M.2    Yoshimoto, T.3    Ehlers, S.4    Hölscher, C.5
  • 51
    • 38449098843 scopus 로고    scopus 로고
    • Augmentation of antigen-presenting and Th1-promoting functions of dendritic cells by WSX-1 (IL-27R) deficiency
    • Wang, S., Y. Miyazaki, Y. Shinozaki, and H. Yoshida. 2007. Augmentation of antigen-presenting and Th1-promoting functions of dendritic cells by WSX-1 (IL-27R) deficiency. J. Immunol. 179: 6421-6428.
    • (2007) J. Immunol. , vol.179 , pp. 6421-6428
    • Wang, S.1    Miyazaki, Y.2    Shinozaki, Y.3    Yoshida, H.4


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