Persistent loss of IL-27 responsiveness in CD8+ memory T cells abrogates IL-10 expression in a recall response

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 45, 2012, Pages 18535-18540

  Perona Wright, Georgia ^a,b   Kohlmeier, Jacob E ^a,c   Bassity, Elizabeth ^a   Freitas, Tori C ^a,d   Mohrs, Katja ^a   Cookenham, Tres ^a   Situ, Haozhong ^b   Pearce, Edward J ^a,e   Woodland, David L ^a,f   Mohrs, Markus ^a  

^a TRUDEAU INSTITUTE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d Myriad RBM   (United States)

^e WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f Keystone Symposia   (United States)

Author keywords

IL 10 reporter mice; Immune regulation; Influenza; Sendai virus; T cell differentiation

Indexed keywords

GAMMA INTERFERON; GLYCOPROTEIN GP 130; INTERLEUKIN 10; INTERLEUKIN 27; RETROVIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; HUMAN; HUMAN CELL; MEMORY CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINE RECEPTOR GP130; DOWN-REGULATION; HUMANS; IMMUNOLOGIC MEMORY; INTERLEUKIN-10; INTERLEUKIN-17; LUNG; MICE; MICE, INBRED C57BL; RESPIRATORY TRACT INFECTIONS; SIGNAL TRANSDUCTION;

MUS; SENDAI VIRUS;

EID: 84868521662     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119133109     Document Type: Article

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