Essential role for IL-27 receptor signaling in prevention of Th1-mediated immunopathology during malaria infection

Journal of Immunology

Volumn 185, Issue 4, 2010, Pages 2482-2492

  Findlay, Emily Gwyer ^a   Greig, Rachel ^a   Stumhofer, Jason S ^c   Hafalla, Julius C R ^a   De Souza, J Brian ^a,b   Saris, Christiaan J ^d   Hunter, Christopher A ^c   Riley, Eleanor M ^a   Couper, Kevin N ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIBODY; GAMMA INTERFERON ANTIBODY; INTERLEUKIN 27; RECOMBINANT INTERLEUKIN 10; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; CYTOKINE; CYTOKINE RECEPTOR; GAMMA INTERFERON; IL27RA PROTEIN, MOUSE; INTERLEUKIN 10; INTERLEUKIN 17;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNOPATHOLOGY; LIVER INJURY; MOUSE; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM BERGHEI INFECTION; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T CELL DEPLETION; TH1 CELL; ANIMAL; BLOOD; C57BL MOUSE; CD8+ T LYMPHOCYTE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; LIVER; LYMPHOCYTE COUNT; MALARIA; MALE; METABOLISM; MOUSE MUTANT; PARASITEMIA; PARASITOLOGY; PATHOLOGY; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-17; LIVER; LYMPHOCYTE COUNT; MALARIA; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARASITEMIA; PLASMODIUM BERGHEI; RECEPTORS, CYTOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TH1 CELLS;

EID: 77956899787     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0904019     Document Type: Article

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