IL-27 alleviates the bleomycin-induced pulmonary fibrosis by regulating the Th17 cell differentiation

BMC Pulmonary Medicine

Volumn 15, Issue 1, 2015, Pages

  Dong, Zhaoxing ^a   Lu, Xin ^a   Yang, Yanni ^a   Zhang, Tao ^a   Li, Yongxia ^a   Chai, Yanlin ^a   Lei, Wen ^a   Li, Changbo ^a   Ai, Li ^a   Tai, Wenlin ^a  

^a KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Animal model; Interleukin 27; Pulmonary fibrosis; Signaling pathway; Th17 cells

Indexed keywords

BLEOMYCIN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; CYTOKINE; EOSIN; GAMMA INTERFERON; HEMATOXYLIN; HYDROXYPROLINE; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 27; INTERLEUKIN 4; INTERLEUKIN 6; INTERLEUKIN RECEPTOR; JANUS KINASE; RECOMBINANT INTERLEUKIN 27; SMAD PROTEIN; SMAD1 PROTEIN; SMAD3 PROTEIN; STAT PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; STAT5 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; ANTINEOPLASTIC ANTIBIOTIC; CYTOKINE RECEPTOR; IL27 PROTEIN, MOUSE; IL27RA PROTEIN, MOUSE; INTERLEUKIN DERIVATIVE; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEOMYCIN-INDUCED PULMONARY FIBROSIS; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; GENE EXPRESSION; LUNG LAVAGE; LUNG PARENCHYMA; LYMPHOCYTE DIFFERENTIATION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPLEEN LYMPHOCYTE; STAINING; SURVIVAL; TH17 CELL; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; C57BL MOUSE; CELL DIFFERENTIATION; CHEMICALLY INDUCED; CYTOLOGY; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETICS; IMMUNOLOGY; LUNG; LUNG FIBROSIS; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN; T LYMPHOCYTE; WESTERN BLOTTING;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; BLOTTING, WESTERN; BRONCHOALVEOLAR LAVAGE FLUID; CELL DIFFERENTIATION; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; INTERLEUKINS; JANUS KINASES; LUNG; MALE; MICE; MICE, INBRED C57BL; PULMONARY FIBROSIS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, CYTOKINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SMAD PROTEINS; SPLEEN; STAT TRANSCRIPTION FACTORS; SUPPRESSOR OF CYTOKINE SIGNALING 3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; T-LYMPHOCYTES; TH17 CELLS; TRANSFORMING GROWTH FACTOR BETA;

EID: 84924049544     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/s12890-015-0012-4     Document Type: Article

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