IL-27R deficiency delays the onset of colitis and protects from helminth-induced pathology in a model of chronic IBD

International Immunology

Volumn 20, Issue 6, 2008, Pages 739-752

  Villarino, Alejandro V ^a,d   Artis, David ^a   Bezbradica, Jelena S ^b,e   Miller, Omer ^d   Saris, Christiaan J M ^c   Joyce, Sebastian ^b   Hunter, Christopher A ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c AMGEN INC   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Colitis; Helminth infection; IFN ; IL 10; IL 27

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 27 RECEPTOR; INTERLEUKIN RECEPTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TBET;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHRONIC DISEASE; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ACTIVITY; DISEASE PREDISPOSITION; ENTERITIS; EXPERIMENTAL MODEL; HELMINTHIASIS; IMMUNE DEFICIENCY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTESTINE INFECTION; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RISK FACTOR; SURVIVAL TIME; TH1 CELL; TH2 CELL; TRICHURIS; TRICHURIS MURIS;

ANIMALS; CHRONIC DISEASE; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-10; MICE; MICE, KNOCKOUT; RECEPTORS, CYTOKINE; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH2 CELLS; TRANSCRIPTION FACTORS; TRICHURIASIS; TRICHURIS;

EID: 44849096815     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxn032     Document Type: Article

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