Two-sided roles of IL-27: Induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism

Journal of Immunology

Volumn 177, Issue 8, 2006, Pages 5377-5385

  Yoshimura, Takeru ^a,b   Takeda, Atsunobu ^a,b   Hamano, Shinjiro ^b   Miyazaki, Yoshiyuki ^a,c,d   Kinjyo, Ichiko ^a   Ishibashi, Tatsuro ^b   Yoshimura, Akihiko ^a   Yoshida, Hiroki ^a,c,d  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d SAGA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; CYTOKINE RECEPTOR; CYTOKINE RECEPTOR WSX 1; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 23; INTERLEUKIN 27; INTERLEUKIN 4; STAT1 PROTEIN; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE DIFFERENTIATION; MONONUCLEAR CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE ACTIVATION; TH1 CELL; WESTERN BLOTTING;

EID: 33749515631     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.8.5377     Document Type: Article

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