IL-27 stimulates human NK-cell effector functions and primes NK cells for IL-18 responsiveness

European Journal of Immunology

Volumn 45, Issue 1, 2015, Pages 192-202

  Ziblat, Andrea ^a,b   Domaica, Carolina I ^a   Spallanzani, Raúl G ^a   Iraolagoitia, Ximena L Raffo ^a   Rossi, Lucas E ^a   Avila, Damián E ^a,c   Torres, Nicolás I ^a,b   Fuertes, Mercedes B ^a,b   Zwirner, Norberto W ^a,b  

^a Facultad de Ciencias Naturales e Instituto M Lillo   (Argentina)

^b UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^c UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

Author keywords

Cytotoxicity; IFN ; IL 18; IL 27; NK cells

Indexed keywords

CD69 ANTIGEN; FAS ANTIGEN; FAS LIGAND; FLUDARABINE; GAMMA INTERFERON; GLYCOPROTEIN GP 130; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 27; INTERLEUKIN 4; INTERLEUKIN 6; JANUS KINASE 2; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; PERFORIN; PHOSPHATIDYLINOSITOL 3 KINASE; STAT1 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; IL27 PROTEIN, HUMAN; IL2RA PROTEIN, HUMAN; IL6ST PROTEIN, HUMAN; INTERLEUKIN 18 PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; LECTIN; LEUKOCYTE ANTIGEN; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; T LYMPHOCYTE ANTIGEN;

ARTICLE; CANCER CELL LINE; CELL MATURATION; CELL MEDIATED CYTOTOXICITY; CELL SURFACE; CELL VIABILITY; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOKINE RESPONSE; DENDRITIC CELL; EFFECTOR CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOCYTOSIS; FLOW CYTOMETRY; HCT116 CELL LINE; HUMAN; HUMAN CELL; LYMPHOCYTE FUNCTION; NATURAL KILLER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAJI CELL LINE; SECRETORY PATHWAY; T 47D CELL; TARGET CELL; UPREGULATION; CELL PROLIFERATION; CELL SURVIVAL; CYTOLOGY; CYTOTOXICITY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CELL PROLIFERATION; CELL SURVIVAL; COCULTURE TECHNIQUES; CYTOKINE RECEPTOR GP130; CYTOTOXICITY, IMMUNOLOGIC; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HCT116 CELLS; HUMANS; INTERLEUKIN-18; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; INTERLEUKINS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; PRIMARY CELL CULTURE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 84921021371     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201444699     Document Type: Article

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