Stress-impaired transcription factor expression and insulin secretion in transplanted human islets

Journal of Clinical Investigation

Volumn 126, Issue 5, 2016, Pages 1857-1870

  Dai, Chunhua ^a   Kayton, Nora S ^a   Shostak, Alena ^a   Poffenberger, Greg ^a   Cyphert, Holly A ^a   Aramandla, Radhika ^a   Thompson, Courtney ^a   Papagiannis, Ioannis G ^a   Emfinger, Christopher ^a   Shiota, Masakazu ^a   Stafford, John M ^a,b   Greiner, Dale L ^c   Herrera, Pedro L ^d   Shultz, Leonard D ^e   Stein, Roland ^a   Powers, Alvin C ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; ANTIOXIDANT; INSULIN; SUPEROXIDE; TRANSCRIPTION FACTOR MAFB; TRANSCRIPTION FACTOR NKX6.1; HOMEODOMAIN PROTEIN; MAFB PROTEIN, HUMAN; NKX6-1 PROTEIN, HUMAN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GLUCOTOXICITY; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN RELEASE; INSULIN RESISTANCE; LIPOTOXICITY; MALE; METABOLIC STRESS; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; KNOCKOUT MOUSE; METABOLISM; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PATHOLOGY; TRANSPLANTATION; XENOGRAFT;

ANIMALS; GENE EXPRESSION REGULATION; HETEROGRAFTS; HOMEODOMAIN PROTEINS; HUMANS; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS TRANSPLANTATION; MAFB TRANSCRIPTION FACTOR; MICE; MICE, KNOCKOUT;

EID: 84987819908     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI83657     Document Type: Article

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