Lipid-induced β-cell dysfunction in vivo in models of progressive β-cell failure

American Journal of Physiology - Endocrinology and Metabolism

Volumn 292, Issue 2, 2007, Pages

  Goh, Tracy T ^a   Mason, Timothy M ^a   Gupta, Neehar ^a   So, Abby ^a   Lam, Tony K T ^a   Lam, Loretta ^a   Lewis, Gary F ^a   Mari, Andrea ^b   Giacca, Adria ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b CNR   (Italy)

Author keywords

Free fatty acid; Hyperglycemic clamp; Insulin secretion; Obesity; Zucker diabetic fatty rat

Indexed keywords

C PEPTIDE; FATTY ACID; GLUCOSE; INSULIN; LEPTIN RECEPTOR; LIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETIC OBESITY; DISEASE COURSE; EXPERIMENTAL MODEL; FEMALE; GENE MUTATION; GLUCOSE BLOOD LEVEL; HETEROZYGOSITY; HYPERGLYCEMIA; IN VIVO STUDY; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; NONHUMAN; PANCREAS FUNCTION; PANCREAS INSUFFICIENCY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; RECEPTOR GENE; WILD TYPE; WISTAR RAT; ZUCKER DIABETIC FATTY RAT; ZUCKER RAT;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; DISEASE MODELS, ANIMAL; FATTY ACIDS, NONESTERIFIED; FEMALE; GLUCOSE CLAMP TECHNIQUE; HYPERGLYCEMIA; INSULIN; INSULIN RESISTANCE; INSULIN-SECRETING CELLS; LIPIDS; PANCREATIC DISEASES; RATS; RATS, WISTAR; RATS, ZUCKER;

EID: 33846855816     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00255.2006     Document Type: Article

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