-
1
-
-
79960202841
-
Type 2 diabetes across generations: From pathophysiology to prevention and management
-
Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet 2011;378:169-181
-
(2011)
Lancet
, vol.378
, pp. 169-181
-
-
Nolan, C.J.1
Damm, P.2
Prentki, M.3
-
2
-
-
0031913829
-
Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat
-
Pick A, Clark J, Kubstrup C, et al. Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. Diabetes 1998;47:358-364
-
(1998)
Diabetes
, vol.47
, pp. 358-364
-
-
Pick, A.1
Clark, J.2
Kubstrup, C.3
-
3
-
-
0038155702
-
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles
-
Brüning JC, Winnay J, Bonner-Weir S, Taylor SI, Accili D, Kahn CR. Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Cell 1997;88:561-572
-
(1997)
Cell
, vol.88
, pp. 561-572
-
-
Brüning, J.C.1
Winnay, J.2
Bonner-Weir, S.3
Taylor, S.I.4
Accili, D.5
Kahn, C.R.6
-
4
-
-
0038707331
-
Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea
-
Yoon KH, Ko SH, Cho JH, et al. Selective beta-cell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 2003;88:2300-2308
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 2300-2308
-
-
Yoon, K.H.1
Ko, S.H.2
Cho, J.H.3
-
5
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003;52:102-110
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
6
-
-
0023850277
-
Quantitative study of insulin secretion and clearance in normal and obese subjects
-
Polonsky KS, Given BD, Hirsch L, et al. Quantitative study of insulin secretion and clearance in normal and obese subjects. J Clin Invest 1988;81: 435-441
-
(1988)
J Clin Invest
, vol.81
, pp. 435-441
-
-
Polonsky, K.S.1
Given, B.D.2
Hirsch, L.3
-
7
-
-
84872035827
-
B-cell mass and turnover in humans: Effects of obesity and aging
-
Saisho Y, Butler AE, Manesso E, Elashoff D, Rizza RA, Butler PC. b-cell mass and turnover in humans: effects of obesity and aging. Diabetes Care 2013;36:111-117
-
(2013)
Diabetes Care
, vol.36
, pp. 111-117
-
-
Saisho, Y.1
Butler, A.E.2
Manesso, E.3
Elashoff, D.4
Rizza, R.A.5
Butler, P.C.6
-
8
-
-
77958040076
-
Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy
-
Butler AE, Cao-Minh L, Galasso R, et al. Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy. Diabetologia 2010;53:2167-2176
-
(2010)
Diabetologia
, vol.53
, pp. 2167-2176
-
-
Butler, A.E.1
Cao-Minh, L.2
Galasso, R.3
-
9
-
-
27744539718
-
Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: Evidence for inappropriate insulin secretion and pancreatic islet hyperplasia
-
Patti ME, McMahon G, Mun EC, et al. Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia. Diabetologia 2005;48:2236-2240
-
(2005)
Diabetologia
, vol.48
, pp. 2236-2240
-
-
Patti, M.E.1
McMahon, G.2
Mun, E.C.3
-
10
-
-
65749113590
-
Glucose toxicity: The leading actor in the pathogenesis and clinical history of type 2 diabetes-mechanisms and potentials for treatment
-
Giaccari A, Sorice G, Muscogiuri G. Glucose toxicity: the leading actor in the pathogenesis and clinical history of type 2 diabetes-mechanisms and potentials for treatment. Nutr Metab Cardiovasc Dis 2009;19:365-377
-
(2009)
Nutr Metab Cardiovasc Dis
, vol.19
, pp. 365-377
-
-
Giaccari, A.1
Sorice, G.2
Muscogiuri, G.3
-
11
-
-
0035130272
-
Beta-cell adaptation and decompensation during the progression of diabetes
-
Weir GC, Laybutt DR, Kaneto H, Bonner-Weir S, Sharma A. Beta-cell adaptation and decompensation during the progression of diabetes. Diabetes 2001;50(Suppl. 1):S154-S159
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Weir, G.C.1
Laybutt, D.R.2
Kaneto, H.3
Bonner-Weir, S.4
Sharma, A.5
-
12
-
-
84871941957
-
Diagnosis and classification of diabetes mellitus
-
American Diabetes Association.
-
American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2013;36(Suppl. 1):S67-S74
-
(2013)
Diabetes Care
, vol.36
, Issue.SUPPL. 1
-
-
-
13
-
-
77957143556
-
25-Hydroxyvitamin D concentration correlates with insulin-sensitivity and BMI in obesity
-
Muscogiuri G, Sorice GP, Prioletta A, et al. 25-Hydroxyvitamin D concentration correlates with insulin-sensitivity and BMI in obesity. Obesity (Silver Spring) 2010;18:1906-1910
-
(2010)
Obesity (Silver Spring)
, vol.18
, pp. 1906-1910
-
-
Muscogiuri, G.1
Sorice, G.P.2
Prioletta, A.3
-
14
-
-
0004165071
-
-
Champaign, IL, Human Kinetics Books
-
Lohman TG, Roche AF, Martorelli R. Anthropometric Standardization Reference Manual. Champaign, IL, Human Kinetics Books, 1988, p. 177
-
(1988)
Anthropometric Standardization Reference Manual
, pp. 177
-
-
Lohman, T.G.1
Roche, A.F.2
Martorelli, R.3
-
15
-
-
0018520840
-
Glucose clamp technique: A method for quantifying insulin secretion and resistance
-
DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979;237:E214-E223
-
(1979)
Am J Physiol
, vol.237
-
-
Defronzo, R.A.1
Tobin, J.D.2
Andres, R.3
-
16
-
-
0038574573
-
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
-
Meier JJ, Gallwitz B, Siepmann N, et al. Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia. Diabetologia 2003;46:798-801
-
(2003)
Diabetologia
, vol.46
, pp. 798-801
-
-
Meier, J.J.1
Gallwitz, B.2
Siepmann, N.3
-
17
-
-
0033766716
-
Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide
-
Deacon CF, Nauck MA, Meier J, Hücking K, Holst JJ. Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide. J Clin Endocrinol Metab 2000;85:3575-3581
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 3575-3581
-
-
Deacon, C.F.1
Nauck, M.A.2
Meier, J.3
Hücking, K.4
Holst, J.J.5
-
18
-
-
0018818265
-
Preservation of the pylorus in pancreaticoduodenectomy a follow-up evaluation
-
Traverso LW, Longmire WP Jr. Preservation of the pylorus in pancreaticoduodenectomy a follow-up evaluation. Ann Surg 1980;192:306-310
-
(1980)
Ann Surg
, vol.192
, pp. 306-310
-
-
Traverso, L.W.1
Longmire Jr., W.P.2
-
19
-
-
84878253263
-
Removal of duodenum elicits GLP-1 secretion
-
Muscogiuri G, Mezza T, Prioletta A, et al. Removal of duodenum elicits GLP-1 secretion. Diabetes Care 2013;36:1641-1646
-
(2013)
Diabetes Care
, vol.36
, pp. 1641-1646
-
-
Muscogiuri, G.1
Mezza, T.2
Prioletta, A.3
-
20
-
-
68549125117
-
Impaired glucose-induced glucagon suppression after partial pancreatectomy
-
Schrader H, Menge BA, Breuer TG, et al. Impaired glucose-induced glucagon suppression after partial pancreatectomy. J Clin Endocrinol Metab 2009;94:2857-2863
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 2857-2863
-
-
Schrader, H.1
Menge, B.A.2
Breuer, T.G.3
-
21
-
-
0024508097
-
Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion
-
Bonner-Weir S, Deery D, Leahy JL, Weir GC. Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes 1989;38:49-53
-
(1989)
Diabetes
, vol.38
, pp. 49-53
-
-
Bonner-Weir, S.1
Deery, D.2
Leahy, J.L.3
Weir, G.C.4
-
22
-
-
0036578921
-
Beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass
-
Kulkarni RN, Holzenberger M, Shih DQ, et al. beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass. Nat Genet 2002;31:111-115
-
(2002)
Nat Genet
, vol.31
, pp. 111-115
-
-
Kulkarni, R.N.1
Holzenberger, M.2
Shih, D.Q.3
-
23
-
-
0033513455
-
Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
-
Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999;48:2270-2276
-
(1999)
Diabetes
, vol.48
, pp. 2270-2276
-
-
Xu, G.1
Stoffers, D.A.2
Habener, J.F.3
Bonner-Weir, S.4
-
24
-
-
0023746613
-
Patterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia
-
Norman JT, Bohman RE, Fischmann G, et al. Patterns of mRNA expression during early cell growth differ in kidney epithelial cells destined to undergo compensatory hypertrophy versus regenerative hyperplasia. Proc Natl Acad Sci U S A 1988;85:6768-6772
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 6768-6772
-
-
Norman, J.T.1
Bohman, R.E.2
Fischmann, G.3
-
25
-
-
0029081447
-
Mechanisms of nonneoplastic endocrine hyperplasia - A changing concept: A review focused on the thyroid gland
-
Studer H, Derwahl M. Mechanisms of nonneoplastic endocrine hyperplasia-a changing concept: a review focused on the thyroid gland. Endocr Rev 1995;16:411-426
-
(1995)
Endocr Rev
, vol.16
, pp. 411-426
-
-
Studer, H.1
Derwahl, M.2
-
26
-
-
0033524937
-
Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes
-
Kulkarni RN, Brüning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 1999;96:329-339
-
(1999)
Cell
, vol.96
, pp. 329-339
-
-
Kulkarni, R.N.1
Brüning, J.C.2
Winnay, J.N.3
Postic, C.4
Magnuson, M.A.5
Kahn, C.R.6
-
27
-
-
59149104922
-
Growth factor control of pancreatic islet regeneration and function
-
Assmann A, Hinault C, Kulkarni RN. Growth factor control of pancreatic islet regeneration and function. Pediatr Diabetes 2009;10:14-32
-
(2009)
Pediatr Diabetes
, vol.10
, pp. 14-32
-
-
Assmann, A.1
Hinault, C.2
Kulkarni, R.N.3
-
28
-
-
84856537444
-
Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulinresistant humans
-
Halperin F, Lopez X, Manning R, Kahn CR, Kulkarni RN, Goldfine AB. Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulinresistant humans. Diabetes 2012;61:301-309
-
(2012)
Diabetes
, vol.61
, pp. 301-309
-
-
Halperin, F.1
Lopez, X.2
Manning, R.3
Kahn, C.R.4
Kulkarni, R.N.5
Goldfine, A.B.6
-
29
-
-
33746412466
-
Hyperinsulinemic hypoglycemia after gastric bypass surgery is not accompanied by islet hyperplasia or increased beta-cell turnover
-
Meier JJ, Butler AE, Galasso R, Butler PC. Hyperinsulinemic hypoglycemia after gastric bypass surgery is not accompanied by islet hyperplasia or increased beta-cell turnover. Diabetes Care 2006;29:1554-1559
-
(2006)
Diabetes Care
, vol.29
, pp. 1554-1559
-
-
Meier, J.J.1
Butler, A.E.2
Galasso, R.3
Butler, P.C.4
-
30
-
-
84893238636
-
Birth and death of human b-cells in pancreas from cadaver donors, autopsies, surgical specimens, and islets transplanted into mice
-
Epub ahead of print
-
Caballero F, Siniakowicz K, Hollister-Lock J, et al. Birth and death of human b-cells in pancreas from cadaver donors, autopsies, surgical specimens, and islets transplanted into mice. Cell Transplant 2 January 2013 [Epub ahead of print]
-
(2013)
Cell Transplant 2 January
-
-
Caballero, F.1
Siniakowicz, K.2
Hollister-Lock, J.3
-
31
-
-
82355161894
-
Altered insulin receptor signalling and b-cell cycle dynamics in type 2 diabetes mellitus
-
Folli F, Okada T, Perego C, et al. Altered insulin receptor signalling and b-cell cycle dynamics in type 2 diabetes mellitus. PLoS ONE 2011;6: e28050
-
(2011)
PLoS ONE
, vol.6
-
-
Folli, F.1
Okada, T.2
Perego, C.3
-
32
-
-
84866153904
-
Formation of a human b-cell population within pancreatic islets is set early in life
-
Gregg BE, Moore PC, Demozay D, et al. Formation of a human b-cell population within pancreatic islets is set early in life. J Clin Endocrinol Metab 2012;97:3197-3206
-
(2012)
J Clin Endocrinol Metab
, vol.97
, pp. 3197-3206
-
-
Gregg, B.E.1
Moore, P.C.2
Demozay, D.3
-
33
-
-
84877691201
-
Predominance of b-cell neogenesis rather than replication in humans with an impaired glucose tolerance and newly diagnosed diabetes
-
Yoneda S, Uno S, Iwahashi H, et al. Predominance of b-cell neogenesis rather than replication in humans with an impaired glucose tolerance and newly diagnosed diabetes. J Clin Endocrinol Metab 2013;98:2053-2061
-
(2013)
J Clin Endocrinol Metab
, vol.98
, pp. 2053-2061
-
-
Yoneda, S.1
Uno, S.2
Iwahashi, H.3
-
34
-
-
75749108616
-
Regenerating pancreatic beta-cells: Plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis
-
Juhl K, Bonner-Weir S, Sharma A. Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis. Curr Opin Organ Transplant 2010;15:79-85
-
(2010)
Curr Opin Organ Transplant
, vol.15
, pp. 79-85
-
-
Juhl, K.1
Bonner-Weir, S.2
Sharma, A.3
-
35
-
-
77958014883
-
Paracrinology of islets and the paracrinopathy of diabetes
-
Unger RH, Orci L. Paracrinology of islets and the paracrinopathy of diabetes. Proc Natl Acad Sci U S A 2010;107:16009-16012
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 16009-16012
-
-
Unger, R.H.1
Orci, L.2
-
36
-
-
63449087896
-
Insulin signaling in alpha cells modulates glucagon secretion in vivo
-
Kawamori D, Kurpad AJ, Hu J, et al. Insulin signaling in alpha cells modulates glucagon secretion in vivo. Cell Metab 2009;9:350-361
-
(2009)
Cell Metab
, vol.9
, pp. 350-361
-
-
Kawamori, D.1
Kurpad, A.J.2
Hu, J.3
-
37
-
-
79959756257
-
Pancreatic alpha cell mass in European subjects with type 2 diabetes
-
Henquin JC, Rahier J. Pancreatic alpha cell mass in European subjects with type 2 diabetes. Diabetologia 2011;54:1720-1725
-
(2011)
Diabetologia
, vol.54
, pp. 1720-1725
-
-
Henquin, J.C.1
Rahier, J.2
-
38
-
-
84881133721
-
Impact of obesity severity and duration on pancreatic b-and a-cell dynamics in normoglycemic non-human primates
-
Guardado-Mendoza R, Jimenez-Ceja L, Majluf-Cruz A, et al. Impact of obesity severity and duration on pancreatic b-and a-cell dynamics in normoglycemic non-human primates. Int J Obes (Lond) 2013;37:1071-1078
-
(2013)
Int J Obes (Lond)
, vol.37
, pp. 1071-1078
-
-
Guardado-Mendoza, R.1
Jimenez-Ceja, L.2
Majluf-Cruz, A.3
-
39
-
-
84866389264
-
Pancreatic b cell dedifferentiation as a mechanism of diabetic b cell failure
-
Talchai C, Xuan S, Lin HV, Sussel L, Accili D. Pancreatic b cell dedifferentiation as a mechanism of diabetic b cell failure. Cell 2012;150:1223-1234
-
(2012)
Cell
, vol.150
, pp. 1223-1234
-
-
Talchai, C.1
Xuan, S.2
Lin, H.V.3
Sussel, L.4
Accili, D.5
-
40
-
-
12244268666
-
On the physiology of GIP and GLP-1
-
Holst JJ. On the physiology of GIP and GLP-1. Horm Metab Res 2004;36: 747-754
-
(2004)
Horm Metab Res
, vol.36
, pp. 747-754
-
-
Holst, J.J.1
-
41
-
-
84868193842
-
A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets
-
Marchetti P, Lupi R, Bugliani M, et al. A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets. Diabetologia 2012;55:3262-3272
-
(2012)
Diabetologia
, vol.55
, pp. 3262-3272
-
-
Marchetti, P.1
Lupi, R.2
Bugliani, M.3
-
42
-
-
12744259876
-
Beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1
-
Li Y, Cao X, Li LX, Brubaker PL, Edlund H, Drucker DJ. beta-Cell Pdx1 expression is essential for the glucoregulatory, proliferative, and cytoprotective actions of glucagon-like peptide-1. Diabetes 2005;54:482-491
-
(2005)
Diabetes
, vol.54
, pp. 482-491
-
-
Li, Y.1
Cao, X.2
Li, L.X.3
Brubaker, P.L.4
Edlund, H.5
Drucker, D.J.6
-
43
-
-
0036679173
-
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
-
Zhu X, Zhou A, Dey A, et al. Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. Proc Natl Acad Sci U S A 2002;99:10293-10298
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10293-10298
-
-
Zhu, X.1
Zhou, A.2
Dey, A.3
-
44
-
-
0345374580
-
Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets
-
Farilla L, Bulotta A, Hirshberg B, et al. Glucagon-like peptide 1 inhibits cell apoptosis and improves glucose responsiveness of freshly isolated human islets. Endocrinology 2003;144:5149-5158
-
(2003)
Endocrinology
, vol.144
, pp. 5149-5158
-
-
Farilla, L.1
Bulotta, A.2
Hirshberg, B.3
-
45
-
-
2942568445
-
Glucagon-like peptide-1 prevents beta cell glucolipotoxicity
-
Buteau J, El-Assaad W, Rhodes CJ, Rosenberg L, Joly E, Prentki M. Glucagon-like peptide-1 prevents beta cell glucolipotoxicity. Diabetologia 2004;47:806-815
-
(2004)
Diabetologia
, vol.47
, pp. 806-815
-
-
Buteau, J.1
El-Assaad, W.2
Rhodes, C.J.3
Rosenberg, L.4
Joly, E.5
Prentki, M.6
-
46
-
-
0037417984
-
Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice
-
Gelling RW, Du XQ, Dichmann DS, et al. Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice. Proc Natl Acad Sci U S A 2003;100:1438-1443
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 1438-1443
-
-
Gelling, R.W.1
Du, X.Q.2
Dichmann, D.S.3
-
47
-
-
85047687525
-
X-box binding protein 1 is essential for insulin regulation of pancreatic a-cell function
-
Akiyama M, Liew CW, Lu S, et al. X-box binding protein 1 is essential for insulin regulation of pancreatic a-cell function. Diabetes 2013;62:2439-2449
-
(2013)
Diabetes
, vol.62
, pp. 2439-2449
-
-
Akiyama, M.1
Liew, C.W.2
Lu, S.3
|