-
1
-
-
34347392646
-
Glucose infusion in mice: a new model to induce beta-cell replication
-
Alonso L.C., Yokoe T., Zhang P., Scott D.K., Kim S.K., O'Donnell C.P., Garcia-Ocaña A. Glucose infusion in mice: a new model to induce beta-cell replication. Diabetes 2007, 56:1792-1801.
-
(2007)
Diabetes
, vol.56
, pp. 1792-1801
-
-
Alonso, L.C.1
Yokoe, T.2
Zhang, P.3
Scott, D.K.4
Kim, S.K.5
O'Donnell, C.P.6
Garcia-Ocaña, A.7
-
2
-
-
79960398834
-
2+ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells
-
2+ concentration, Slc39 (ZiP), and metallothionein gene expression in primary pancreatic islet β-cells. J.Biol. Chem. 2011, 286:25778-25789.
-
(2011)
J.Biol. Chem.
, vol.286
, pp. 25778-25789
-
-
Bellomo, E.A.1
Meur, G.2
Rutter, G.A.3
-
3
-
-
34250370060
-
Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE)
-
Bhinge A.A., Kim J., Euskirchen G.M., Snyder M., Iyer V.R. Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE). Genome Res. 2007, 17:910-916.
-
(2007)
Genome Res.
, vol.17
, pp. 910-916
-
-
Bhinge, A.A.1
Kim, J.2
Euskirchen, G.M.3
Snyder, M.4
Iyer, V.R.5
-
4
-
-
0024508097
-
Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion
-
Bonner-Weir S., Deery D., Leahy J.L., Weir G.C. Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes 1989, 38:49-53.
-
(1989)
Diabetes
, vol.38
, pp. 49-53
-
-
Bonner-Weir, S.1
Deery, D.2
Leahy, J.L.3
Weir, G.C.4
-
5
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler A.E., Janson J., Bonner-Weir S., Ritzel R., Rizza R.A., Butler P.C. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003, 52:102-110.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
6
-
-
0014095480
-
The plasma insulin response to glucose infusion in healthy subjects and in diabetes mellitus
-
Cerasi E., Luft R. The plasma insulin response to glucose infusion in healthy subjects and in diabetes mellitus. Acta Endocrinol. (Copenh.) 1967, 55:278-304.
-
(1967)
Acta Endocrinol. (Copenh.)
, vol.55
, pp. 278-304
-
-
Cerasi, E.1
Luft, R.2
-
7
-
-
77954323314
-
The stunned beta cell: a brief history
-
Ferrannini E. The stunned beta cell: a brief history. Cell Metab. 2010, 11:349-352.
-
(2010)
Cell Metab.
, vol.11
, pp. 349-352
-
-
Ferrannini, E.1
-
8
-
-
64649104150
-
Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function invivo
-
Fiaschi-Taesch N., Bigatel T.A., Sicari B., Takane K.K., Salim F., Velazquez-Garcia S., Harb G., Selk K., Cozar-Castellano I., Stewart A.F. Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function invivo. Diabetes 2009, 58:882-893.
-
(2009)
Diabetes
, vol.58
, pp. 882-893
-
-
Fiaschi-Taesch, N.1
Bigatel, T.A.2
Sicari, B.3
Takane, K.K.4
Salim, F.5
Velazquez-Garcia, S.6
Harb, G.7
Selk, K.8
Cozar-Castellano, I.9
Stewart, A.F.10
-
9
-
-
0026608764
-
Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus
-
Froguel P., Vaxillaire M., Sun F., Velho G., Zouali H., Butel M.O., Lesage S., Vionnet N., Clément K., Fougerousse F., et al. Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus. Nature 1992, 356:162-164.
-
(1992)
Nature
, vol.356
, pp. 162-164
-
-
Froguel, P.1
Vaxillaire, M.2
Sun, F.3
Velho, G.4
Zouali, H.5
Butel, M.O.6
Lesage, S.7
Vionnet, N.8
Clément, K.9
Fougerousse, F.10
-
10
-
-
9644266753
-
Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass
-
Georgia S., Bhushan A. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. J.Clin. Invest. 2004, 114:963-968.
-
(2004)
J.Clin. Invest.
, vol.114
, pp. 963-968
-
-
Georgia, S.1
Bhushan, A.2
-
11
-
-
26444479437
-
Granuphilin molecularly docks insulin granules to the fusion machinery
-
Gomi H., Mizutani S., Kasai K., Itohara S., Izumi T. Granuphilin molecularly docks insulin granules to the fusion machinery. J.Cell Biol. 2005, 171:99-109.
-
(2005)
J.Cell Biol.
, vol.171
, pp. 99-109
-
-
Gomi, H.1
Mizutani, S.2
Kasai, K.3
Itohara, S.4
Izumi, T.5
-
12
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G., Dubauskaite J., Melton D.A. Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 2002, 129:2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
13
-
-
0033857373
-
Glucose uptake, utilization, and signaling in GLUT2-null islets
-
Guillam M.T., Dupraz P., Thorens B. Glucose uptake, utilization, and signaling in GLUT2-null islets. Diabetes 2000, 49:1485-1491.
-
(2000)
Diabetes
, vol.49
, pp. 1485-1491
-
-
Guillam, M.T.1
Dupraz, P.2
Thorens, B.3
-
14
-
-
84881218353
-
Inactivation of specific β cell transcription factors in type 2 diabetes
-
Published online July 1, 2013
-
Guo S., Dai C., Guo M., Taylor B., Harmon J.S., Sander M., Robertson R.P., Powers A.C., Stein R. Inactivation of specific β cell transcription factors in type 2 diabetes. J.Clin. Invest. 2013, Published online July 1, 2013. 10.1172/JCI65390.
-
(2013)
J.Clin. Invest.
-
-
Guo, S.1
Dai, C.2
Guo, M.3
Taylor, B.4
Harmon, J.S.5
Sander, M.6
Robertson, R.P.7
Powers, A.C.8
Stein, R.9
-
15
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz S., Benner C., Spann N., Bertolino E., Lin Y.C., Laslo P., Cheng J.X., Murre C., Singh H., Glass C.K. Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell 2010, 38:576-589.
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
Cheng, J.X.7
Murre, C.8
Singh, H.9
Glass, C.K.10
-
16
-
-
0024354876
-
Similar reduction of first- and second-phase B-cell responses at three different glucose levels in type II diabetes and the effect of gliclazide therapy
-
Hosker J.P., Rudenski A.S., Burnett M.A., Matthews D.R., Turner R.C. Similar reduction of first- and second-phase B-cell responses at three different glucose levels in type II diabetes and the effect of gliclazide therapy. Metabolism 1989, 38:767-772.
-
(1989)
Metabolism
, vol.38
, pp. 767-772
-
-
Hosker, J.P.1
Rudenski, A.S.2
Burnett, M.A.3
Matthews, D.R.4
Turner, R.C.5
-
17
-
-
56449107474
-
BioVenn - a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams
-
Hulsen T., de Vlieg J., Alkema W. BioVenn - a web application for the comparison and visualization of biological lists using area-proportional Venn diagrams. BMC Genomics 2008, 9:488.
-
(2008)
BMC Genomics
, vol.9
, pp. 488
-
-
Hulsen, T.1
de Vlieg, J.2
Alkema, W.3
-
18
-
-
0033553462
-
Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes
-
Jonas J.C., Sharma A., Hasenkamp W., Ilkova H., Patanè G., Laybutt R., Bonner-Weir S., Weir G.C. Chronic hyperglycemia triggers loss of pancreatic beta cell differentiation in an animal model of diabetes. J.Biol. Chem. 1999, 274:14112-14121.
-
(1999)
J.Biol. Chem.
, vol.274
, pp. 14112-14121
-
-
Jonas, J.C.1
Sharma, A.2
Hasenkamp, W.3
Ilkova, H.4
Patanè, G.5
Laybutt, R.6
Bonner-Weir, S.7
Weir, G.C.8
-
19
-
-
0032716367
-
Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1
-
Jørgensen M.C., Vestergård Petersen H., Ericson J., Madsen O.D., Serup P. Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1. FEBS Lett. 1999, 461:287-294.
-
(1999)
FEBS Lett.
, vol.461
, pp. 287-294
-
-
Jørgensen, M.C.1
Vestergård Petersen, H.2
Ericson, J.3
Madsen, O.D.4
Serup, P.5
-
20
-
-
17644387563
-
Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth
-
Kushner J.A., Ciemerych M.A., Sicinska E., Wartschow L.M., Teta M., Long S.Y., Sicinski P., White M.F. Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth. Mol. Cell. Biol. 2005, 25:3752-3762.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 3752-3762
-
-
Kushner, J.A.1
Ciemerych, M.A.2
Sicinska, E.3
Wartschow, L.M.4
Teta, M.5
Long, S.Y.6
Sicinski, P.7
White, M.F.8
-
21
-
-
34247279657
-
Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis
-
Li C., Chen P., Vaughan J., Lee K.F., Vale W. Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis. Proc. Natl. Acad. Sci. USA 2007, 104:4206-4211.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 4206-4211
-
-
Li, C.1
Chen, P.2
Vaughan, J.3
Lee, K.F.4
Vale, W.5
-
22
-
-
39749147110
-
Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes
-
Muoio D.M., Newgard C.B. Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Nat. Rev. Mol. Cell Biol. 2008, 9:193-205.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 193-205
-
-
Muoio, D.M.1
Newgard, C.B.2
-
23
-
-
70349113136
-
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants
-
Nicolson T.J., Bellomo E.A., Wijesekara N., Loder M.K., Baldwin J.M., Gyulkhandanyan A.V., Koshkin V., Tarasov A.I., Carzaniga R., Kronenberger K., et al. Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants. Diabetes 2009, 58:2070-2083.
-
(2009)
Diabetes
, vol.58
, pp. 2070-2083
-
-
Nicolson, T.J.1
Bellomo, E.A.2
Wijesekara, N.3
Loder, M.K.4
Baldwin, J.M.5
Gyulkhandanyan, A.V.6
Koshkin, V.7
Tarasov, A.I.8
Carzaniga, R.9
Kronenberger, K.10
-
24
-
-
0021335764
-
Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell
-
Orci L., Ravazzola M., Amherdt M., Yanaihara C., Yanaihara N., Halban P., Renold A.E., Perrelet A. Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell. J.Cell Biol. 1984, 98:222-228.
-
(1984)
J.Cell Biol.
, vol.98
, pp. 222-228
-
-
Orci, L.1
Ravazzola, M.2
Amherdt, M.3
Yanaihara, C.4
Yanaihara, N.5
Halban, P.6
Renold, A.E.7
Perrelet, A.8
-
25
-
-
0038522555
-
Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass invivo in adult rats
-
Paris M., Bernard-Kargar C., Berthault M.F., Bouwens L., Ktorza A. Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass invivo in adult rats. Endocrinology 2003, 144:2717-2727.
-
(2003)
Endocrinology
, vol.144
, pp. 2717-2727
-
-
Paris, M.1
Bernard-Kargar, C.2
Berthault, M.F.3
Bouwens, L.4
Ktorza, A.5
-
26
-
-
0015446766
-
An ultrastructural analysis of the developing embryonic pancreas
-
Pictet R.L., Clark W.R., Williams R.H., Rutter W.J. An ultrastructural analysis of the developing embryonic pancreas. Dev. Biol. 1972, 29:436-467.
-
(1972)
Dev. Biol.
, vol.29
, pp. 436-467
-
-
Pictet, R.L.1
Clark, W.R.2
Williams, R.H.3
Rutter, W.J.4
-
27
-
-
0033534726
-
Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretion
-
Piston D.W., Knobel S.M., Postic C., Shelton K.D., Magnuson M.A. Adenovirus-mediated knockout of a conditional glucokinase gene in isolated pancreatic islets reveals an essential role for proximal metabolic coupling events in glucose-stimulated insulin secretion. J.Biol. Chem. 1999, 274:1000-1004.
-
(1999)
J.Biol. Chem.
, vol.274
, pp. 1000-1004
-
-
Piston, D.W.1
Knobel, S.M.2
Postic, C.3
Shelton, K.D.4
Magnuson, M.A.5
-
28
-
-
79953734660
-
Control of pancreatic β cell regeneration by glucose metabolism
-
Porat S., Weinberg-Corem N., Tornovsky-Babaey S., Schyr-Ben-Haroush R., Hija A., Stolovich-Rain M., Dadon D., Granot Z., Ben-Hur V., White P., et al. Control of pancreatic β cell regeneration by glucose metabolism. Cell Metab. 2011, 13:440-449.
-
(2011)
Cell Metab.
, vol.13
, pp. 440-449
-
-
Porat, S.1
Weinberg-Corem, N.2
Tornovsky-Babaey, S.3
Schyr-Ben-Haroush, R.4
Hija, A.5
Stolovich-Rain, M.6
Dadon, D.7
Granot, Z.8
Ben-Hur, V.9
White, P.10
-
29
-
-
11144357764
-
Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors
-
Preitner F., Ibberson M., Franklin I., Binnert C., Pende M., Gjinovci A., Hansotia T., Drucker D.J., Wollheim C., Burcelin R., Thorens B. Gluco-incretins control insulin secretion at multiple levels as revealed in mice lacking GLP-1 and GIP receptors. J.Clin. Invest. 2004, 113:635-645.
-
(2004)
J.Clin. Invest.
, vol.113
, pp. 635-645
-
-
Preitner, F.1
Ibberson, M.2
Franklin, I.3
Binnert, C.4
Pende, M.5
Gjinovci, A.6
Hansotia, T.7
Drucker, D.J.8
Wollheim, C.9
Burcelin, R.10
Thorens, B.11
-
30
-
-
5644248079
-
Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes
-
Robertson R.P. Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes. J.Biol. Chem. 2004, 279:42351-42354.
-
(2004)
J.Biol. Chem.
, vol.279
, pp. 42351-42354
-
-
Robertson, R.P.1
-
31
-
-
77956562845
-
Glucose and aging control the quiescence period that follows pancreatic beta cell replication
-
Salpeter S.J., Klein A.M., Huangfu D., Grimsby J., Dor Y. Glucose and aging control the quiescence period that follows pancreatic beta cell replication. Development 2010, 137:3205-3213.
-
(2010)
Development
, vol.137
, pp. 3205-3213
-
-
Salpeter, S.J.1
Klein, A.M.2
Huangfu, D.3
Grimsby, J.4
Dor, Y.5
-
32
-
-
79959396928
-
Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels
-
Salpeter S.J., Klochendler A., Weinberg-Corem N., Porat S., Granot Z., Shapiro A.M., Magnuson M.A., Eden A., Grimsby J., Glaser B., Dor Y. Glucose regulates cyclin D2 expression in quiescent and replicating pancreatic β-cells through glycolysis and calcium channels. Endocrinology 2011, 152:2589-2598.
-
(2011)
Endocrinology
, vol.152
, pp. 2589-2598
-
-
Salpeter, S.J.1
Klochendler, A.2
Weinberg-Corem, N.3
Porat, S.4
Granot, Z.5
Shapiro, A.M.6
Magnuson, M.A.7
Eden, A.8
Grimsby, J.9
Glaser, B.10
Dor, Y.11
-
33
-
-
0033844629
-
Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates
-
Sander M., Paydar S., Ericson J., Briscoe J., Berber E., German M., Jessell T.M., Rubenstein J.L. Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates. Genes Dev. 2000, 14:2134-2139.
-
(2000)
Genes Dev.
, vol.14
, pp. 2134-2139
-
-
Sander, M.1
Paydar, S.2
Ericson, J.3
Briscoe, J.4
Berber, E.5
German, M.6
Jessell, T.M.7
Rubenstein, J.L.8
-
34
-
-
77955978501
-
Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors
-
Schaffer A.E., Freude K.K., Nelson S.B., Sander M. Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors. Dev. Cell 2010, 18:1022-1029.
-
(2010)
Dev. Cell
, vol.18
, pp. 1022-1029
-
-
Schaffer, A.E.1
Freude, K.K.2
Nelson, S.B.3
Sander, M.4
-
35
-
-
80054997189
-
Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance
-
Schaffer A.E., Yang A.J., Thorel F., Herrera P.L., Sander M. Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance. Mol. Endocrinol. 2011, 25:1904-1914.
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 1904-1914
-
-
Schaffer, A.E.1
Yang, A.J.2
Thorel, F.3
Herrera, P.L.4
Sander, M.5
-
36
-
-
84873514082
-
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity
-
Schaffer A.E., Taylor B.L., Benthuysen J.R., Liu J., Thorel F., Yuan W., Jiao Y., Kaestner K.H., Herrera P.L., Magnuson M.A., et al. Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity. PLoS Genet. 2013, 9:e1003274.
-
(2013)
PLoS Genet.
, vol.9
-
-
Schaffer, A.E.1
Taylor, B.L.2
Benthuysen, J.R.3
Liu, J.4
Thorel, F.5
Yuan, W.6
Jiao, Y.7
Kaestner, K.H.8
Herrera, P.L.9
Magnuson, M.A.10
-
37
-
-
21044433282
-
The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells
-
Schisler J.C., Jensen P.B., Taylor D.G., Becker T.C., Knop F.K., Takekawa S., German M., Weir G.C., Lu D., Mirmira R.G., Newgard C.B. The Nkx6.1 homeodomain transcription factor suppresses glucagon expression and regulates glucose-stimulated insulin secretion in islet beta cells. Proc. Natl. Acad. Sci. USA 2005, 102:7297-7302.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 7297-7302
-
-
Schisler, J.C.1
Jensen, P.B.2
Taylor, D.G.3
Becker, T.C.4
Knop, F.K.5
Takekawa, S.6
German, M.7
Weir, G.C.8
Lu, D.9
Mirmira, R.G.10
Newgard, C.B.11
-
38
-
-
43249122991
-
Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1
-
Schisler J.C., Fueger P.T., Babu D.A., Hohmeier H.E., Tessem J.S., Lu D., Becker T.C., Naziruddin B., Levy M., Mirmira R.G., Newgard C.B. Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1. Mol. Cell. Biol. 2008, 28:3465-3476.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 3465-3476
-
-
Schisler, J.C.1
Fueger, P.T.2
Babu, D.A.3
Hohmeier, H.E.4
Tessem, J.S.5
Lu, D.6
Becker, T.C.7
Naziruddin, B.8
Levy, M.9
Mirmira, R.G.10
Newgard, C.B.11
-
39
-
-
0028604486
-
STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells
-
Schnedl W.J., Ferber S., Johnson J.H., Newgard C.B. STZ transport and cytotoxicity. Specific enhancement in GLUT2-expressing cells. Diabetes 1994, 43:1326-1333.
-
(1994)
Diabetes
, vol.43
, pp. 1326-1333
-
-
Schnedl, W.J.1
Ferber, S.2
Johnson, J.H.3
Newgard, C.B.4
-
40
-
-
84865418540
-
Mitochondrial dysfunction in pancreatic β cells
-
Supale S., Li N., Brun T., Maechler P. Mitochondrial dysfunction in pancreatic β cells. Trends Endocrinol. Metab. 2012, 23:477-487.
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 477-487
-
-
Supale, S.1
Li, N.2
Brun, T.3
Maechler, P.4
-
41
-
-
84866389264
-
Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure
-
Talchai C., Xuan S., Lin H.V., Sussel L., Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell 2012, 150:1223-1234.
-
(2012)
Cell
, vol.150
, pp. 1223-1234
-
-
Talchai, C.1
Xuan, S.2
Lin, H.V.3
Sussel, L.4
Accili, D.5
-
42
-
-
0029417331
-
Pancreatic beta-cell-specifictargeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose
-
Terauchi Y., Sakura H., Yasuda K., Iwamoto K., Takahashi N., Ito K., Kasai H., Suzuki H., Ueda O., Kamada N., et al. Pancreatic beta-cell-specifictargeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. J.Biol. Chem. 1995, 270:30253-30256.
-
(1995)
J.Biol. Chem.
, vol.270
, pp. 30253-30256
-
-
Terauchi, Y.1
Sakura, H.2
Yasuda, K.3
Iwamoto, K.4
Takahashi, N.5
Ito, K.6
Kasai, H.7
Suzuki, H.8
Ueda, O.9
Kamada, N.10
-
43
-
-
24144473869
-
Very slow turnover of beta-cells in aged adult mice
-
Teta M., Long S.Y., Wartschow L.M., Rankin M.M., Kushner J.A. Very slow turnover of beta-cells in aged adult mice. Diabetes 2005, 54:2557-2567.
-
(2005)
Diabetes
, vol.54
, pp. 2557-2567
-
-
Teta, M.1
Long, S.Y.2
Wartschow, L.M.3
Rankin, M.M.4
Kushner, J.A.5
-
44
-
-
0032918044
-
A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse
-
Wang J., Takeuchi T., Tanaka S., Kubo S.K., Kayo T., Lu D., Takata K., Koizumi A., Izumi T. A mutation in the insulin 2 gene induces diabetes with severe pancreatic beta-cell dysfunction in the Mody mouse. J.Clin. Invest. 1999, 103:27-37.
-
(1999)
J.Clin. Invest.
, vol.103
, pp. 27-37
-
-
Wang, J.1
Takeuchi, T.2
Tanaka, S.3
Kubo, S.K.4
Kayo, T.5
Lu, D.6
Takata, K.7
Koizumi, A.8
Izumi, T.9
-
45
-
-
34248191270
-
Lineage tracing evidence for invitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells
-
Weinberg N., Ouziel-Yahalom L., Knoller S., Efrat S., Dor Y. Lineage tracing evidence for invitro dedifferentiation but rare proliferation of mouse pancreatic beta-cells. Diabetes 2007, 56:1299-1304.
-
(2007)
Diabetes
, vol.56
, pp. 1299-1304
-
-
Weinberg, N.1
Ouziel-Yahalom, L.2
Knoller, S.3
Efrat, S.4
Dor, Y.5
-
46
-
-
0142149134
-
Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin
-
Wicksteed B., Alarcon C., Briaud I., Lingohr M.K., Rhodes C.J. Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin. J.Biol. Chem. 2003, 278:42080-42090.
-
(2003)
J.Biol. Chem.
, vol.278
, pp. 42080-42090
-
-
Wicksteed, B.1
Alarcon, C.2
Briaud, I.3
Lingohr, M.K.4
Rhodes, C.J.5
-
47
-
-
0029951161
-
Conservation and diversification in homeodomain-DNA interactions: a comparative genetic analysis
-
Wilson D.S., Sheng G., Jun S., Desplan C. Conservation and diversification in homeodomain-DNA interactions: a comparative genetic analysis. Proc. Natl. Acad. Sci. USA 1996, 93:6886-6891.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 6886-6891
-
-
Wilson, D.S.1
Sheng, G.2
Jun, S.3
Desplan, C.4
-
48
-
-
33749351977
-
Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects
-
Yokoi N., Kanamori M., Horikawa Y., Takeda J., Sanke T., Furuta H., Nanjo K., Mori H., Kasuga M., Hara K., et al. Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects. Diabetes 2006, 55:2379-2386.
-
(2006)
Diabetes
, vol.55
, pp. 2379-2386
-
-
Yokoi, N.1
Kanamori, M.2
Horikawa, Y.3
Takeda, J.4
Sanke, T.5
Furuta, H.6
Nanjo, K.7
Mori, H.8
Kasuga, M.9
Hara, K.10
-
49
-
-
0036678101
-
Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3
-
Zhu X., Orci L., Carroll R., Norrbom C., Ravazzola M., Steiner D.F. Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3. Proc. Natl. Acad. Sci. USA 2002, 99:10299-10304.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10299-10304
-
-
Zhu, X.1
Orci, L.2
Carroll, R.3
Norrbom, C.4
Ravazzola, M.5
Steiner, D.F.6
-
50
-
-
77949716997
-
ERO1-beta, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis
-
Zito E., Chin K.T., Blais J., Harding H.P., Ron D. ERO1-beta, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis. J.Cell Biol. 2010, 188:821-832.
-
(2010)
J.Cell Biol.
, vol.188
, pp. 821-832
-
-
Zito, E.1
Chin, K.T.2
Blais, J.3
Harding, H.P.4
Ron, D.5
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