Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 8, 1996, Pages 3492-3496

  Verchere, C Bruce ^a,b   D'Alessio, David A ^a   Palmiter, Richard D ^a   Weir, Gordon C ^c   Bonner Weir, Susan ^c   Baskin, Denis G ^a,b   Kahn, Steven E ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

glucose; insulin; non insulin dependent diabetes mellitus

Indexed keywords

AMYLIN; AMYLOID; GLUCOSE;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DIABETOGENESIS; DISEASE PREDISPOSITION; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; ULTRASTRUCTURE;

AMYLOID; ANIMALS; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION; HUMANS; HYPERGLYCEMIA; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MICROSCOPY, IMMUNOELECTRON; RECOMBINANT PROTEINS;

EID: 0029978228     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.8.3492     Document Type: Article

References (34)

1. Westermark, P. (1972) Uppsala J. Med. Sci. 77, 91-94.
2. Clark, A., Cooper, G. J. S., Lewis, C. E., Morris, J. F., Willis, A. C., Reid, K. B. M. & Turner, R. C. (1987) Lancet ii, 231-234.
3. Clark, A., Saad, M. F., Nezzer, T., Uren, C., Knowler, W. C., Bennett, P. H. & Turner, R. C. (1990) Diabetologia 33, 285-289.
4. Westermark, P., Wernstedt, C., Wilander, E. & Sletten, K. (1986) Biochem. Biophys. Res. Commun. 140, 827-831.
5. Westermark, P., Wernstedt, C., Wilander, E., Hayden, D. W., O'Brien, T. D. & Johnson, K. H. (1987) Proc. Natl. Acad. Sci. USA 84, 3881-3885.
6. Cooper, G. J. S., Willis, A. C., Clark, A., Turner, R. C., Sim, R. B. & Reid, K. B. M. (1987) Proc. Natl. Acad. Sci. USA 84, 8628-8632.
7. Lukinius, A., Wilander, E., Westermark, G. T., Engstrom, U. & Westermark, P. (1989) Diabetologia 32, 240-244.
8. Kahn, S. E., D'Alessio, D. A., Schwartz, M. W., Fujimoto, W. Y., Ensinck, J. W., Taborsky, G. J., Jr., & Porte, D., Jr. (1990) Diabetes 39, 634-638.
9. Porte, D., Jr. (1991) Diabetes 40, 166-180.
10. Lorenzo, A., Razzaboni, B., Weir, G. C. & Yankner, B. A. (1994) Nature (London) 368, 756-760.
11. Howard, C. F., Jr. (1986) Diabetologia 29, 301-306.
12. Glenner, G. G., Eanes, E. D. & Wiley. C. A. (1988) Biochem. Biophys. Res. Commun. 155, 608-614.
13. Betsholtz, C., Christmanson, L., Engstrom, U., Rorsman, F., Jordan, K., O'Brien, T. D., Murtaugh, M., Johnson, K. H. & Westermark, P. (1990) Diabetes 39, 118-122.
14. D'Alessio, D. A., Verchere, C. B., Kahn, S. E., Hoagland, V., Baskin, D. G., Palmiter, R. D. & Ensinck, J. W. (1994) Diabetes 43, 1457-1461.
15. Fox, N., Schrementi, J., Nishi, M., Ohagi, S., Chan, S. J., Heisserman, J., Westermark, G. T., Leckstrom, A., Westermark, P. & Steiner, D. F. (1993) FEBS Lett. 323, 40-44.
16. Hoppener, J. W. M., Verbeek, J. S., de Koning, E. J. P., Oosterwijk, C., van Hulst, K. L., Visser-Vernooy, H. J., Hofhuis, F. M. A., van Gaalen, S., Berends, M. J. H., Hackeng, W. H. L., Jansz, H. S., Morris, J. F., Clark, A., Capel, P. J. A. & Lips, C. J. M. (1993) Diabetologia 36, 1258-1265.
17. Verchere, C. B., D'Alessio, D. A., Palmiter, R. D. & Kahn, S. E (1994) Diabetologia 37, 725-728.
18. Verchere, C. B., D'Alessio. D. A. & Kahn, S. E. (1996) in Lessons from Animal Diabetes VI, ed. Shrafrir, E. (Birkhauser, Boston, MA), in press.
19. Morgan, D. R. & Lazarow, A. (1963) Diabetes 12, 115-126.
20. Schwartz, P. (1970) Amyloidosis: Cause and Manifestation of Senile Dementia (Thomas, Springfield, IL).
21. Puchtler, H., Sweat, F. & Levine, M. (1962) J Histochem. Cytochem. 10, 355-364.
22. Games, D., Adams, D., Alessandrini, R., Barbour, R., Berthelette, P., et al. (1995) Nature (London) 373, 523-527.
23. Johnson, K. H., O'Brien, T. D., Hayden, D. W., Jordan, K., Ghobrial, H. K. G., Mahoney, W. C. & Westermark, P. (1988) Am. J. Pathol. 130, 1-8.
24. Clark, A., Edwards, C. A., Ostle, L. R., Sutton, R., Rothbard, J. B., Morris, J. F. & Turner. R. C. (1989) Cell Tissue Res. 257, 179-185.
25. Bell, E. T. (1959) Am. J. Pathol. 35, 801-805.
26. Kava, R., West, D. B., Lukasik, V. A. & Greenwood, M. R. C. (1989) Diabetes 38, 159-163.
27. Leiter, E. H., Chapman, H. D. & Coleman, D. L. (1989) Endocrinology 124, 912-922.
28. Lowell, B. B., S-Susulic, V., Hamann, A., Lawitts, J. A., Himms-Hagen, J., Boyer, B. B., Kozak, L. P. & Flier, J. S. (1993) Nature (London) 366, 740-742.
29. Kahn, S. E., Prigeon, R. L., McCulloch, D. K., Boyko, E. J., Bergman, R. N., Schwartz. M. W., Neifing, J. L., Ward, W. K., Beard, J. C., Palmer, J. P. & Porte, D., Jr. (1993) Diabetes 42, 1663-1672.
30. Sako, Y. & Grill, V. E. (1990) Endocrinology 127, 1580-1589.
31. de Koning, E. J. P., Morris, E. R., Hofhuis, F. M. A., Posthuma, G., Hoppener, J. W. M., Morris, J. F., Capel, P. J. A., Clark, A. & Verbeek, J. S. (1994) Proc. Natl. Acad. Sci. USA 91, 8467-8471.
32. Kaku, K., Fiedorek, F. T. J., Province, M. & Permutt, M. A. (1988) Diabetes 37, 707-713.
33. Surwit, R. S., Kuhn, C. M., Cochrane, C, McCubbin, J. A. & Feinglos, M. N. (1988) Diabetes 37, 1163-1167.
34. Leiter, E. H. (1989) FASEB J. 3, 2231-2241.