-
2
-
-
67650720510
-
Immune and inflammatory mechanisms of atherosclerosis
-
Galkina E, Ley K. Immune and inflammatory mechanisms of atherosclerosis. Annu Rev Immunol 2009; 27: 165-197.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 165-197
-
-
Galkina, E.1
Ley, K.2
-
4
-
-
78650698895
-
Functional and pathological roles of the 12- and 15-lipoxygenases
-
Dobrian AD, Lieb DC, Cole BK, Taylor-Fishwick DA, Chakrabarti SK, Nadler JL. Functional and pathological roles of the 12- and 15-lipoxygenases. Prog Lipid Res 2011; 50: 115-131.
-
(2011)
Prog Lipid Res
, vol.50
, pp. 115-131
-
-
Dobrian, A.D.1
Lieb, D.C.2
Cole, B.K.3
Taylor-Fishwick, D.A.4
Chakrabarti, S.K.5
Nadler, J.L.6
-
5
-
-
0033966938
-
Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2
-
Jisaka M, Kim RB, Boeglin WE, Brash AR. Identification of amino acid determinants of the positional specificity of mouse 8S-lipoxygenase and human 15S-lipoxygenase-2. J Biol Chem 2000; 275: 1287-1293.
-
(2000)
J Biol Chem
, vol.275
, pp. 1287-1293
-
-
Jisaka, M.1
Kim, R.B.2
Boeglin, W.E.3
Brash, A.R.4
-
6
-
-
84879692780
-
-
Cole BK, Lieb DC, Dobrian AD, Nadler JL. 12- and 15-lipoxygenases in adipose tissue inflammation. Prostaglandins Other Lipid Mediat
-
Cole BK, Lieb DC, Dobrian AD, Nadler JL. 12- and 15-lipoxygenases in adipose tissue inflammation. Prostaglandins Other Lipid Mediat 2013; 104-105: 84-92.
-
(2013)
, vol.104-105
, pp. 84-92
-
-
-
7
-
-
0033278323
-
Mammalian 15-lipoxygenases. Enzymatic properties and biological implications
-
Kuhn H, Borngraber S. Mammalian 15-lipoxygenases. Enzymatic properties and biological implications. Adv Exp Med Biol 1999; 447: 5-28.
-
(1999)
Adv Exp Med Biol
, vol.447
, pp. 5-28
-
-
Kuhn, H.1
Borngraber, S.2
-
8
-
-
0036669583
-
Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications
-
Kuhn H, Walther M, Kuban RJ. Mammalian arachidonate 15-lipoxygenases structure, function, and biological implications. Prostaglandins Other Lipid Mediat 2002; 68-69: 263-290.
-
(2002)
Prostaglandins Other Lipid Mediat
, vol.68-69
, pp. 263-290
-
-
Kuhn, H.1
Walther, M.2
Kuban, R.J.3
-
9
-
-
57049099790
-
12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet
-
Nunemaker CS, Chen M, Pei H et al. 12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by Western diet. Am J Physiol Endocrinol Metab 2008; 295: E1065-E1075.
-
(2008)
Am J Physiol Endocrinol Metab
, vol.295
-
-
Nunemaker, C.S.1
Chen, M.2
Pei, H.3
-
10
-
-
70349639659
-
12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice
-
Sears DD, Miles PD, Chapman J et al. 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice. PLoS One 2009; 4: e7250.
-
(2009)
PLoS One
, vol.4
-
-
Sears, D.D.1
Miles, P.D.2
Chapman, J.3
-
11
-
-
69749102190
-
12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes
-
Chakrabarti SK, Cole BK, Wen Y, Keller SR, Nadler JL. 12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes. Obesity (Silver Spring) 2009; 17: 1657-1663.
-
(2009)
Obesity (Silver Spring)
, vol.17
, pp. 1657-1663
-
-
Chakrabarti, S.K.1
Cole, B.K.2
Wen, Y.3
Keller, S.R.4
Nadler, J.L.5
-
12
-
-
78650788269
-
Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats
-
Chakrabarti SK, Wen Y, Dobrian AD et al. Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats. Am J Physiol Endocrinol Metab 2011; 300: E175-E187.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
-
-
Chakrabarti, S.K.1
Wen, Y.2
Dobrian, A.D.3
-
13
-
-
62749104401
-
Endoplasmic reticulum stress: another link between obesity and insulin resistance/inflammation?
-
Boden G. Endoplasmic reticulum stress: another link between obesity and insulin resistance/inflammation? Diabetes 2009; 58: 518-519.
-
(2009)
Diabetes
, vol.58
, pp. 518-519
-
-
Boden, G.1
-
15
-
-
84872779944
-
Adipose tissue-specific deletion of 12/15-lipoxygenase protects mice from the consequences of a high-fat diet
-
Cole BK, Morris MA, Grzesik WJ, Leone KA, Nadler JL. Adipose tissue-specific deletion of 12/15-lipoxygenase protects mice from the consequences of a high-fat diet. Mediators Inflamm 2012; 2012: 851798.
-
(2012)
Mediators Inflamm
, vol.2012
, pp. 851798
-
-
Cole, B.K.1
Morris, M.A.2
Grzesik, W.J.3
Leone, K.A.4
Nadler, J.L.5
-
16
-
-
77149139835
-
Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice
-
Cole BK, Keller SR, Wu R, Carter JD, Nadler JL, Nunemaker CS. Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice. Hypertension 2010; 55: 715-721.
-
(2010)
Hypertension
, vol.55
, pp. 715-721
-
-
Cole, B.K.1
Keller, S.R.2
Wu, R.3
Carter, J.D.4
Nadler, J.L.5
Nunemaker, C.S.6
-
17
-
-
40349100270
-
Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus
-
Serhan CN, Chiang N. Endogenous pro-resolving and anti-inflammatory lipid mediators: a new pharmacologic genus. Br J Pharmacol 2008; 153(Suppl. 1): S200-S215.
-
(2008)
Br J Pharmacol
, vol.153
, Issue.SUPPL. 1
-
-
Serhan, C.N.1
Chiang, N.2
-
18
-
-
42649089790
-
Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators
-
Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol 2008; 8: 349-361.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 349-361
-
-
Serhan, C.N.1
Chiang, N.2
Van Dyke, T.E.3
-
19
-
-
41749090254
-
Anti-inflammatory and proresolving lipid mediators
-
Serhan CN, Yacoubian S, Yang R. Anti-inflammatory and proresolving lipid mediators. Annu Rev Pathol 2008; 3: 279-312.
-
(2008)
Annu Rev Pathol
, vol.3
, pp. 279-312
-
-
Serhan, C.N.1
Yacoubian, S.2
Yang, R.3
-
20
-
-
60549107724
-
Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions
-
Serhan CN, Yang R, Martinod K et al. Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions. J Exp Med 2009; 206: 15-23.
-
(2009)
J Exp Med
, vol.206
, pp. 15-23
-
-
Serhan, C.N.1
Yang, R.2
Martinod, K.3
-
21
-
-
24344510350
-
Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX
-
Chiang N, Arita M, Serhan CN. Anti-inflammatory circuitry: lipoxin, aspirin-triggered lipoxins and their receptor ALX. Prostaglandins Leukot Essent Fatty Acids 2005; 73: 163-177.
-
(2005)
Prostaglandins Leukot Essent Fatty Acids
, vol.73
, pp. 163-177
-
-
Chiang, N.1
Arita, M.2
Serhan, C.N.3
-
22
-
-
81455131791
-
Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype
-
Titos E, Rius B, Gonzalez-Periz A et al. Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype. J Immunol 2011; 187: 5408-5418.
-
(2011)
J Immunol
, vol.187
, pp. 5408-5418
-
-
Titos, E.1
Rius, B.2
Gonzalez-Periz, A.3
-
23
-
-
84861440668
-
12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance
-
Uderhardt S, Herrmann M, Oskolkova OV et al. 12/15-lipoxygenase orchestrates the clearance of apoptotic cells and maintains immunologic tolerance. Immunity 2012; 36: 834-846.
-
(2012)
Immunity
, vol.36
, pp. 834-846
-
-
Uderhardt, S.1
Herrmann, M.2
Oskolkova, O.V.3
-
24
-
-
70349740767
-
PRESS echo time behavior of triglyceride resonances at 1.5T: detecting omega-3 fatty acids in adipose tissue in vivo
-
Lundbom J, Heikkinen S, Fielding B, Hakkarainen A, Taskinen MR, Lundbom N. PRESS echo time behavior of triglyceride resonances at 1.5T: detecting omega-3 fatty acids in adipose tissue in vivo. J Magn Reson 2009; 201: 39-47.
-
(2009)
J Magn Reson
, vol.201
, pp. 39-47
-
-
Lundbom, J.1
Heikkinen, S.2
Fielding, B.3
Hakkarainen, A.4
Taskinen, M.R.5
Lundbom, N.6
-
25
-
-
67649363782
-
Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins
-
Gonzalez-Periz A, Horrillo R, Ferre N et al. Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins. FASEB J 2009; 23: 1946-1957.
-
(2009)
FASEB J
, vol.23
, pp. 1946-1957
-
-
Gonzalez-Periz, A.1
Horrillo, R.2
Ferre, N.3
-
26
-
-
78650173914
-
Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects
-
Dobrian AD, Lieb DC, Ma Q et al. Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects. Biochem Biophys Res Commun 2010; 403: 485-490.
-
(2010)
Biochem Biophys Res Commun
, vol.403
, pp. 485-490
-
-
Dobrian, A.D.1
Lieb, D.C.2
Ma, Q.3
-
27
-
-
0028998879
-
A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II
-
Kim JA, Gu JL, Natarajan R, Berliner JA, Nadler JL. A leukocyte type of 12-lipoxygenase is expressed in human vascular and mononuclear cells. Evidence for upregulation by angiotensin II. Arterioscler Thromb Vasc Biol 1995; 15: 942-948.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 942-948
-
-
Kim, J.A.1
Gu, J.L.2
Natarajan, R.3
Berliner, J.A.4
Nadler, J.L.5
-
28
-
-
0027166718
-
Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies
-
Chen XS, Funk CD. Structure-function properties of human platelet 12-lipoxygenase: chimeric enzyme and in vitro mutagenesis studies. FASEB J 1993; 7: 694-701.
-
(1993)
FASEB J
, vol.7
, pp. 694-701
-
-
Chen, X.S.1
Funk, C.D.2
-
29
-
-
78751618979
-
Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in human obesity
-
Gealekman O, Guseva N, Hartigan C et al. Depot-specific differences and insufficient subcutaneous adipose tissue angiogenesis in human obesity. Circulation 2011; 123: 186-194.
-
(2011)
Circulation
, vol.123
, pp. 186-194
-
-
Gealekman, O.1
Guseva, N.2
Hartigan, C.3
-
30
-
-
84879130007
-
-
Claria J, Nguyen BT, Madenci A, Ozaki CK, Serhan CN. Diversity of lipid mediators in human adipose tissue depots. Am J Physiol Cell Physiol
-
Claria J, Nguyen BT, Madenci A, Ozaki CK, Serhan CN. Diversity of lipid mediators in human adipose tissue depots. Am J Physiol Cell Physiol 2013; 304: C1141-1149.
-
(2013)
, vol.304
-
-
-
31
-
-
84871608983
-
Production and function of IL-12 in islets and beta cells
-
Taylor-Fishwick DA, Weaver JR, Grzesik W et al. Production and function of IL-12 in islets and beta cells. Diabetologia 2013; 56: 126-135.
-
(2013)
Diabetologia
, vol.56
, pp. 126-135
-
-
Taylor-Fishwick, D.A.1
Weaver, J.R.2
Grzesik, W.3
-
32
-
-
84860488264
-
Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction
-
Weaver JR, Holman TR, Imai Y et al. Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction. Mol Cell Endocrinol 2012; 358: 88-95.
-
(2012)
Mol Cell Endocrinol
, vol.358
, pp. 88-95
-
-
Weaver, J.R.1
Holman, T.R.2
Imai, Y.3
-
33
-
-
76149125754
-
12-Lipoxygenase products reduce insulin secretion and {beta}-cell viability in human islets
-
Ma K, Nunemaker CS, Wu R, Chakrabarti SK, Taylor-Fishwick DA, Nadler JL. 12-Lipoxygenase products reduce insulin secretion and {beta}-cell viability in human islets. J Clin Endocrinol Metab 2010; 95: 887-893.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 887-893
-
-
Ma, K.1
Nunemaker, C.S.2
Wu, R.3
Chakrabarti, S.K.4
Taylor-Fishwick, D.A.5
Nadler, J.L.6
-
34
-
-
79961219253
-
Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase
-
Kenyon V, Rai G, Jadhav A et al. Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. J Med Chem 2011; 54: 5485-5497.
-
(2011)
J Med Chem
, vol.54
, pp. 5485-5497
-
-
Kenyon, V.1
Rai, G.2
Jadhav, A.3
-
35
-
-
0032723345
-
Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice
-
Bleich D, Chen S, Zipser B, Sun D, Funk CD, Nadler JL. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice. J Clin Invest 1999; 103: 1431-1436.
-
(1999)
J Clin Invest
, vol.103
, pp. 1431-1436
-
-
Bleich, D.1
Chen, S.2
Zipser, B.3
Sun, D.4
Funk, C.D.5
Nadler, J.L.6
-
36
-
-
38449098081
-
Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes
-
McDuffie M, Maybee NA, Keller SR et al. Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes. Diabetes 2008; 57: 199-208.
-
(2008)
Diabetes
, vol.57
, pp. 199-208
-
-
McDuffie, M.1
Maybee, N.A.2
Keller, S.R.3
-
37
-
-
84874339055
-
Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-alox15(null) mice, leading to protection against type 1 diabetes development
-
Green-Mitchell SM, Tersey SA, Cole BK et al. Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-alox15(null) mice, leading to protection against type 1 diabetes development. PLoS One 2013; 8: e56763.
-
(2013)
PLoS One
, vol.8
-
-
Green-Mitchell, S.M.1
Tersey, S.A.2
Cole, B.K.3
-
38
-
-
84859553400
-
Islet beta-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model
-
Tersey SA, Nishiki Y, Templin AT et al. Islet beta-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model. Diabetes 2012; 61: 818-827.
-
(2012)
Diabetes
, vol.61
, pp. 818-827
-
-
Tersey, S.A.1
Nishiki, Y.2
Templin, A.T.3
-
39
-
-
0037192853
-
Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia
-
Laybutt DR, Sharma A, Sgroi DC, Gaudet J, Bonner-Weir S, Weir GC. Genetic regulation of metabolic pathways in beta-cells disrupted by hyperglycemia. J Biol Chem 2002; 277: 10912-10921.
-
(2002)
J Biol Chem
, vol.277
, pp. 10912-10921
-
-
Laybutt, D.R.1
Sharma, A.2
Sgroi, D.C.3
Gaudet, J.4
Bonner-Weir, S.5
Weir, G.C.6
-
40
-
-
0028874383
-
Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat
-
Tokuyama Y, Sturis J, DePaoli AM et al. Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. Diabetes 1995; 44: 1447-1457.
-
(1995)
Diabetes
, vol.44
, pp. 1447-1457
-
-
Tokuyama, Y.1
Sturis, J.2
DePaoli, A.M.3
-
41
-
-
77955658618
-
Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes
-
Igoillo-Esteve M, Marselli L, Cunha DA et al. Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes. Diabetologia 2010; 53: 1395-1405.
-
(2010)
Diabetologia
, vol.53
, pp. 1395-1405
-
-
Igoillo-Esteve, M.1
Marselli, L.2
Cunha, D.A.3
-
42
-
-
77950290798
-
{beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes
-
Hanley SC, Austin E, Assouline-Thomas B et al. {beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes. Endocrinology 2010; 151: 1462-1472.
-
(2010)
Endocrinology
, vol.151
, pp. 1462-1472
-
-
Hanley, S.C.1
Austin, E.2
Assouline-Thomas, B.3
-
43
-
-
0037002096
-
Pancreatic cell lineage analyses in mice
-
Herrera PL, Nepote V, Delacour A. Pancreatic cell lineage analyses in mice. Endocrine 2002; 19: 267-278.
-
(2002)
Endocrine
, vol.19
, pp. 267-278
-
-
Herrera, P.L.1
Nepote, V.2
Delacour, A.3
-
44
-
-
72449156523
-
Single pancreatic beta cells co-express multiple islet hormone genes in mice
-
Katsuta H, Akashi T, Katsuta R et al. Single pancreatic beta cells co-express multiple islet hormone genes in mice. Diabetologia 2010; 53: 128-138.
-
(2010)
Diabetologia
, vol.53
, pp. 128-138
-
-
Katsuta, H.1
Akashi, T.2
Katsuta, R.3
-
45
-
-
84866389264
-
Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure
-
Talchai C, Xuan S, Lin HV, Sussel L, Accili D. Pancreatic beta cell dedifferentiation as a mechanism of diabetic beta cell failure. Cell 2012; 150: 1223-1234.
-
(2012)
Cell
, vol.150
, pp. 1223-1234
-
-
Talchai, C.1
Xuan, S.2
Lin, H.V.3
Sussel, L.4
Accili, D.5
-
46
-
-
45249089262
-
Oxidative stress: the vulnerable beta-cell
-
Lenzen S. Oxidative stress: the vulnerable beta-cell. Biochem Soc Trans 2008; 36: 343-347.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 343-347
-
-
Lenzen, S.1
-
47
-
-
59649115492
-
Pancreatic islets are very poor in rectifying oxidative DNA damage
-
Modak MA, Parab PB, Ghaskadbi SS. Pancreatic islets are very poor in rectifying oxidative DNA damage. Pancreas 2009; 38: 23-29.
-
(2009)
Pancreas
, vol.38
, pp. 23-29
-
-
Modak, M.A.1
Parab, P.B.2
Ghaskadbi, S.S.3
-
48
-
-
77956951626
-
Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic beta-cell dysfunction
-
Michalska M, Wolf G, Walther R, Newsholme P. Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic beta-cell dysfunction. Biosci Rep 2010; 30: 445-453.
-
(2010)
Biosci Rep
, vol.30
, pp. 445-453
-
-
Michalska, M.1
Wolf, G.2
Walther, R.3
Newsholme, P.4
-
49
-
-
0034684963
-
Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines
-
Janciauskiene S, Ahren B. Fibrillar islet amyloid polypeptide differentially affects oxidative mechanisms and lipoprotein uptake in correlation with cytotoxicity in two insulin-producing cell lines. Biochem Biophys Res Commun 2000; 267: 619-625.
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 619-625
-
-
Janciauskiene, S.1
Ahren, B.2
-
50
-
-
34250340017
-
Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line
-
Morgan D, Oliveira-Emilio HR, Keane D et al. Glucose, palmitate and pro-inflammatory cytokines modulate production and activity of a phagocyte-like NADPH oxidase in rat pancreatic islets and a clonal beta cell line. Diabetologia 2007; 50: 359-369.
-
(2007)
Diabetologia
, vol.50
, pp. 359-369
-
-
Morgan, D.1
Oliveira-Emilio, H.R.2
Keane, D.3
-
51
-
-
20444407654
-
Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist
-
Nakayama M, Inoguchi T, Sonta T et al. Increased expression of NAD(P)H oxidase in islets of animal models of Type 2 diabetes and its improvement by an AT1 receptor antagonist. Biochem Biophys Res Commun 2005; 332: 927-933.
-
(2005)
Biochem Biophys Res Commun
, vol.332
, pp. 927-933
-
-
Nakayama, M.1
Inoguchi, T.2
Sonta, T.3
-
52
-
-
0037645789
-
Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase
-
Oliveira HR, Verlengia R, Carvalho CR, Britto LR, Curi R, Carpinelli AR. Pancreatic beta-cells express phagocyte-like NAD(P)H oxidase. Diabetes 2003; 52: 1457-1463.
-
(2003)
Diabetes
, vol.52
, pp. 1457-1463
-
-
Oliveira, H.R.1
Verlengia, R.2
Carvalho, C.R.3
Britto, L.R.4
Curi, R.5
Carpinelli, A.R.6
-
53
-
-
33845194611
-
Expression of isoforms of NADPH oxidase components in rat pancreatic islets
-
Uchizono Y, Takeya R, Iwase M et al. Expression of isoforms of NADPH oxidase components in rat pancreatic islets. Life Sci 2006; 80: 133-139.
-
(2006)
Life Sci
, vol.80
, pp. 133-139
-
-
Uchizono, Y.1
Takeya, R.2
Iwase, M.3
-
54
-
-
27844494151
-
L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis
-
Cunningham GA, McClenaghan NH, Flatt PR, Newsholme P. L-Alanine induces changes in metabolic and signal transduction gene expression in a clonal rat pancreatic beta-cell line and protects from pro-inflammatory cytokine-induced apoptosis. Clin Sci (Lond) 2005; 109: 447-455.
-
(2005)
Clin Sci (Lond)
, vol.109
, pp. 447-455
-
-
Cunningham, G.A.1
McClenaghan, N.H.2
Flatt, P.R.3
Newsholme, P.4
-
55
-
-
21444439103
-
NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome
-
Inoguchi T, Nawata H. NAD(P)H oxidase activation: a potential target mechanism for diabetic vascular complications, progressive beta-cell dysfunction and metabolic syndrome. Curr Drug Targets 2005; 6: 495-501.
-
(2005)
Curr Drug Targets
, vol.6
, pp. 495-501
-
-
Inoguchi, T.1
Nawata, H.2
-
56
-
-
34547830983
-
Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity
-
Newsholme P, Haber EP, Hirabara SM et al. Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity. J Physiol 2007; 583: 9-24.
-
(2007)
J Physiol
, vol.583
, pp. 9-24
-
-
Newsholme, P.1
Haber, E.P.2
Hirabara, S.M.3
-
57
-
-
77957301909
-
The endoplasmic reticulum stress response in the pancreatic beta-cell
-
Volchuk A, Ron D. The endoplasmic reticulum stress response in the pancreatic beta-cell. Diabetes Obes Metab 2010; 12(Suppl. 2): 48-57.
-
(2010)
Diabetes Obes Metab
, vol.12
, Issue.SUPPL. 2
, pp. 48-57
-
-
Volchuk, A.1
Ron, D.2
-
58
-
-
84892578338
-
-
Matti A, Kyathanahalli C, Kowluru A. Protein farnesylation is requisite for mitochondrial fuel-induced insulin release: further evidence to link reactive oxygen species generation to insulin secretion in pancreatic beta-cells. Islets
-
Matti A, Kyathanahalli C, Kowluru A. Protein farnesylation is requisite for mitochondrial fuel-induced insulin release: further evidence to link reactive oxygen species generation to insulin secretion in pancreatic beta-cells. Islets 2012; 4: 74-77.
-
(2012)
, vol.4
, pp. 74-77
-
-
-
59
-
-
80755184724
-
Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet
-
Syed I, Kyathanahalli CN, Jayaram B et al. Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1-JNK1/2 signaling pathway in mitochondrial dysregulation in the diabetic islet. Diabetes 2011; 60: 2843-2852.
-
(2011)
Diabetes
, vol.60
, pp. 2843-2852
-
-
Syed, I.1
Kyathanahalli, C.N.2
Jayaram, B.3
-
60
-
-
79952780609
-
Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation
-
Syed I, Kyathanahalli CN, Kowluru A. Phagocyte-like NADPH oxidase generates ROS in INS 832/13 cells and rat islets: role of protein prenylation. Am J Physiol Regul Integr Comp Physiol 2011; 300: R756-R762.
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.300
-
-
Syed, I.1
Kyathanahalli, C.N.2
Kowluru, A.3
-
61
-
-
84867332588
-
NADPH oxidase 2 plays a critical role in dysfunction and apoptosis of pancreatic beta-cells induced by very low-density lipoprotein
-
Jiao J, Dou L, Li M et al. NADPH oxidase 2 plays a critical role in dysfunction and apoptosis of pancreatic beta-cells induced by very low-density lipoprotein. Mol Cell Biochem 2012; 370: 103-113.
-
(2012)
Mol Cell Biochem
, vol.370
, pp. 103-113
-
-
Jiao, J.1
Dou, L.2
Li, M.3
-
62
-
-
78650852744
-
NADPH oxidase 2-derived reactive oxygen species mediate FFAs-induced dysfunction and apoptosis of beta-cells via JNK, p38 MAPK and p53 pathways
-
Yuan H, Zhang X, Huang X et al. NADPH oxidase 2-derived reactive oxygen species mediate FFAs-induced dysfunction and apoptosis of beta-cells via JNK, p38 MAPK and p53 pathways. PLoS One 2010; 5: e15726.
-
(2010)
PLoS One
, vol.5
-
-
Yuan, H.1
Zhang, X.2
Huang, X.3
-
63
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
-
Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007; 87: 245-313.
-
(2007)
Physiol Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
64
-
-
84875032358
-
Regulation of NOX-1 expression in beta cells: a positive feedback loop involving the Src-kinase signaling pathway
-
Weaver JR, Taylor-Fishwick DA. Regulation of NOX-1 expression in beta cells: a positive feedback loop involving the Src-kinase signaling pathway. Mol Cell Endocrinol 2013; 369: 35-41.
-
(2013)
Mol Cell Endocrinol
, vol.369
, pp. 35-41
-
-
Weaver, J.R.1
Taylor-Fishwick, D.A.2
-
65
-
-
1642412663
-
Autoimmune diabetes is blocked in Stat4-deficient mice
-
Yang Z, Chen M, Ellett JD et al. Autoimmune diabetes is blocked in Stat4-deficient mice. J Autoimmun 2004; 22: 191-200.
-
(2004)
J Autoimmun
, vol.22
, pp. 191-200
-
-
Yang, Z.1
Chen, M.2
Ellett, J.D.3
-
66
-
-
1642273986
-
The novel anti-inflammatory compound, lisofylline, prevents diabetes in multiple low-dose streptozotocin-treated mice
-
Yang Z, Chen M, Fialkow LB, Ellett JD, Wu R, Nadler JL. The novel anti-inflammatory compound, lisofylline, prevents diabetes in multiple low-dose streptozotocin-treated mice. Pancreas 2003; 26: e99-e104.
-
(2003)
Pancreas
, vol.26
-
-
Yang, Z.1
Chen, M.2
Fialkow, L.B.3
Ellett, J.D.4
Wu, R.5
Nadler, J.L.6
-
67
-
-
84859417816
-
Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis
-
Rong S, Cao Q, Liu M et al. Macrophage 12/15 lipoxygenase expression increases plasma and hepatic lipid levels and exacerbates atherosclerosis. J Lipid Res 2012; 53: 686-695.
-
(2012)
J Lipid Res
, vol.53
, pp. 686-695
-
-
Rong, S.1
Cao, Q.2
Liu, M.3
-
68
-
-
77953519631
-
Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study
-
Burdon KP, Rudock ME, Lehtinen AB et al. Human lipoxygenase pathway gene variation and association with markers of subclinical atherosclerosis in the diabetes heart study. Mediators Inflamm 2010; 2010: 170153.
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 170153
-
-
Burdon, K.P.1
Rudock, M.E.2
Lehtinen, A.B.3
-
69
-
-
80155193136
-
Current views on the functions of interleukin-17A-producing cells in atherosclerosis
-
Butcher M, Galkina E. Current views on the functions of interleukin-17A-producing cells in atherosclerosis. Thromb Haemost 2011; 106: 787-795.
-
(2011)
Thromb Haemost
, vol.106
, pp. 787-795
-
-
Butcher, M.1
Galkina, E.2
-
70
-
-
79251589063
-
Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes
-
Jagannathan-Bogdan M, McDonnell ME, Shin H et al. Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes. J Immunol 2011; 186: 1162-1172.
-
(2011)
J Immunol
, vol.186
, pp. 1162-1172
-
-
Jagannathan-Bogdan, M.1
McDonnell, M.E.2
Shin, H.3
-
71
-
-
84856104448
-
Roles of interleukin 17 in angiotensin II type 1 receptor-mediated insulin resistance
-
Ohshima K, Mogi M, Jing F et al. Roles of interleukin 17 in angiotensin II type 1 receptor-mediated insulin resistance. Hypertension 2012; 59: 493-499.
-
(2012)
Hypertension
, vol.59
, pp. 493-499
-
-
Ohshima, K.1
Mogi, M.2
Jing, F.3
-
72
-
-
74949108521
-
Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction
-
Madhur MS, Lob HE, McCann LA et al. Interleukin 17 promotes angiotensin II-induced hypertension and vascular dysfunction. Hypertension 2010; 55: 500-507.
-
(2010)
Hypertension
, vol.55
, pp. 500-507
-
-
Madhur, M.S.1
Lob, H.E.2
McCann, L.A.3
-
73
-
-
84857922610
-
The IL-17A/IL-17RA axis plays a proatherogenic role via the regulation of aortic myeloid cell recruitment
-
Butcher MJ, Gjurich BN, Phillips T, Galkina EV. The IL-17A/IL-17RA axis plays a proatherogenic role via the regulation of aortic myeloid cell recruitment. Circ Res 2012; 110: 675-687.
-
(2012)
Circ Res
, vol.110
, pp. 675-687
-
-
Butcher, M.J.1
Gjurich, B.N.2
Phillips, T.3
Galkina, E.V.4
-
74
-
-
33144489526
-
Novel human lipoxygenase inhibitors discovered using virtual screening with homology models
-
Kenyon V, Chorny I, Carvajal WJ, Holman TR, Jacobson MP. Novel human lipoxygenase inhibitors discovered using virtual screening with homology models. J Med Chem 2006; 49: 1356-1363.
-
(2006)
J Med Chem
, vol.49
, pp. 1356-1363
-
-
Kenyon, V.1
Chorny, I.2
Carvajal, W.J.3
Holman, T.R.4
Jacobson, M.P.5
|